Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	postsynaptic specialization	PKP4 DAPK1 GRID1 ADCY1 CHRNE AURKA PTK2B DLGAP3 LRFN5 LRP4 NUMB NOS1 SHISA6	3.73e-05	503	141	13	GO:0099572
GeneOntologyCellularComponent	neuron to neuron synapse	CALCA PKP4 DAPK1 GRID1 ADCY1 AURKA PTK2B DLGAP3 LRFN5 LRP4 NUMB NOS1 SHISA6	5.55e-05	523	141	13	GO:0098984
GeneOntologyCellularComponent	postsynaptic density	PKP4 DAPK1 GRID1 ADCY1 AURKA PTK2B DLGAP3 LRFN5 LRP4 NUMB NOS1 SHISA6	5.69e-05	451	141	12	GO:0014069
GeneOntologyCellularComponent	asymmetric synapse	PKP4 DAPK1 GRID1 ADCY1 AURKA PTK2B DLGAP3 LRFN5 LRP4 NUMB NOS1 SHISA6	9.68e-05	477	141	12	GO:0032279
GeneOntologyCellularComponent	postsynapse	PKP4 LAMA2 DAPK1 GRID1 ADCY1 CHRNE CHRNG AURKA PTK2B DLGAP3 LRFN5 LRP4 NUMB WASF1 NOS1 AP3D1 SHISA6 SENP5	1.73e-04	1018	141	18	GO:0098794
HumanPheno	Enlarged naris	NSD1 NALCN UNC80	1.54e-05	6	48	3	HP:0009931
Domain	ARM-type_fold	USP34 STK36 PKP4 HUWE1 USP9Y CLHC1 URB1 NBEAL2 DIAPH3 WDFY3 AP3D1	4.74e-05	339	139	11	IPR016024
Domain	-	TRIM49 FGD2 TRIM49C NSD1 TRIM49D1 TRIM27 CXXC1 FGD4 SH3RF2 WDFY3 TRIM49B RNF111	1.36e-04	449	139	12	3.30.40.10
Domain	NPIP	NPIPB3 NPIPB5 NPIPB13	1.38e-04	14	139	3	IPR009443
Domain	RhoGEF	FGD2 ARHGEF38 PLEKHG4B FGD4 PLEKHG3	1.52e-04	68	139	5	SM00325
Domain	BBOX	TRIM49 TRIM49C TRIM49D1 TRIM27 TRIM49B	1.63e-04	69	139	5	SM00336
Domain	Znf_RING/FYVE/PHD	TRIM49 FGD2 TRIM49C NSD1 TRIM49D1 TRIM27 CXXC1 FGD4 SH3RF2 WDFY3 TRIM49B RNF111	1.67e-04	459	139	12	IPR013083
Domain	Butyrophylin	TRIM49 TRIM49C TRIM49D1 TRIM27 TRIM49B	1.74e-04	70	139	5	IPR003879
Domain	RhoGEF	FGD2 ARHGEF38 PLEKHG4B FGD4 PLEKHG3	1.74e-04	70	139	5	PF00621
Domain	DH_2	FGD2 ARHGEF38 PLEKHG4B FGD4 PLEKHG3	1.74e-04	70	139	5	PS50010
Domain	-	FGD2 ARHGEF38 PLEKHG4B FGD4 PLEKHG3	1.86e-04	71	139	5	1.20.900.10
Domain	DH-domain	FGD2 ARHGEF38 PLEKHG4B FGD4 PLEKHG3	1.86e-04	71	139	5	IPR000219
Domain	-	TRIM49 TRIM49C TRIM49D1 TRIM27 TRIM49B	1.86e-04	71	139	5	4.10.45.10
Domain	zf-B_box	TRIM49 TRIM49C TRIM49D1 TRIM27 TRIM49B	1.99e-04	72	139	5	PF00643
Domain	ConA-like_dom	TRIM49 TRIM49C LAMA2 TRIM49D1 TRIM27 NBEAL2 WDFY3 TRIM49B	2.38e-04	219	139	8	IPR013320
Domain	ZF_BBOX	TRIM49 TRIM49C TRIM49D1 TRIM27 TRIM49B	3.26e-04	80	139	5	PS50119
Domain	Znf_B-box	TRIM49 TRIM49C TRIM49D1 TRIM27 TRIM49B	3.46e-04	81	139	5	IPR000315
Domain	RING	TRIM49 TRIM49C NSD1 TRIM49D1 TRIM27 SH3RF2 NFX1 TRIM49B RNF111	4.71e-04	305	139	9	SM00184
Domain	SPRY	TRIM49 TRIM49C TRIM49D1 TRIM27 TRIM49B	4.81e-04	87	139	5	SM00449
Domain	UDPGT	UGT2A3 UGT2A1 UGT2B15	4.86e-04	21	139	3	PF00201
Domain	UDPGT	UGT2A3 UGT2A1 UGT2B15	4.86e-04	21	139	3	PS00375
Domain	UDP_glucos_trans	UGT2A3 UGT2A1 UGT2B15	4.86e-04	21	139	3	IPR002213
Domain	DUF4704	NBEAL2 WDFY3	5.42e-04	5	139	2	IPR031570
Domain	DUF4704	NBEAL2 WDFY3	5.42e-04	5	139	2	PF15787
Domain	SPRY	TRIM49 TRIM49C TRIM49D1 TRIM27 TRIM49B	6.86e-04	94	139	5	PF00622
Domain	SPRY_dom	TRIM49 TRIM49C TRIM49D1 TRIM27 TRIM49B	6.86e-04	94	139	5	IPR003877
Domain	B30.2/SPRY	TRIM49 TRIM49C TRIM49D1 TRIM27 TRIM49B	7.20e-04	95	139	5	IPR001870
Domain	B302_SPRY	TRIM49 TRIM49C TRIM49D1 TRIM27 TRIM49B	7.20e-04	95	139	5	PS50188
Domain	Znf_RING	TRIM49 TRIM49C NSD1 TRIM49D1 TRIM27 SH3RF2 NFX1 TRIM49B RNF111	7.58e-04	326	139	9	IPR001841
Domain	-	EVPL PLEC	8.09e-04	6	139	2	3.90.1290.10
Domain	PH_BEACH	NBEAL2 WDFY3	8.09e-04	6	139	2	PF14844
Domain	ARM-like	STK36 PKP4 HUWE1 USP9Y NBEAL2 WDFY3 MN1 AP3D1	9.48e-04	270	139	8	IPR011989
Domain	Plectin	EVPL PLEC	1.13e-03	7	139	2	PF00681
Domain	Plectin_repeat	EVPL PLEC	1.13e-03	7	139	2	IPR001101
Domain	PLEC	EVPL PLEC	1.13e-03	7	139	2	SM00250
Domain	FYVE	FGD2 FGD4 WDFY3	1.28e-03	29	139	3	PF01363
Domain	FYVE	FGD2 FGD4 WDFY3	1.28e-03	29	139	3	SM00064
Domain	PH_dom-like	FGD2 PLEKHG4B PTK2B SHC2 FGD4 PLEKHG3 NBEAL2 NUMB WDFY3 PLEKHA8	1.34e-03	426	139	10	IPR011993
Domain	PH-BEACH_dom	NBEAL2 WDFY3	1.50e-03	8	139	2	IPR023362
Domain	-	NBEAL2 WDFY3	1.50e-03	8	139	2	2.30.29.40
Domain	PH_BEACH	NBEAL2 WDFY3	1.50e-03	8	139	2	PS51783
Domain	ZF_RING_2	TRIM49 TRIM49C TRIM49D1 TRIM27 SH3RF2 NFX1 TRIM49B RNF111	1.77e-03	298	139	8	PS50089
Domain	BEACH	NBEAL2 WDFY3	1.91e-03	9	139	2	PS50197
Domain	Beach	NBEAL2 WDFY3	1.91e-03	9	139	2	PF02138
Domain	-	NBEAL2 WDFY3	1.91e-03	9	139	2	1.10.1540.10
Domain	Beach	NBEAL2 WDFY3	1.91e-03	9	139	2	SM01026
Domain	BEACH_dom	NBEAL2 WDFY3	1.91e-03	9	139	2	IPR000409
Domain	Znf_FYVE-rel	FGD2 FGD4 WDFY3	2.04e-03	34	139	3	IPR017455
Domain	Znf_FYVE	FGD2 FGD4 WDFY3	2.81e-03	38	139	3	IPR000306
Domain	ZF_FYVE	FGD2 FGD4 WDFY3	3.26e-03	40	139	3	PS50178
Domain	Znf_FYVE_PHD	FGD2 NSD1 CXXC1 FGD4 WDFY3	4.88e-03	147	139	5	IPR011011
Domain	Post-SET_dom	NSD1 EHMT2	6.16e-03	16	139	2	IPR003616
Domain	PostSET	NSD1 EHMT2	6.16e-03	16	139	2	SM00508
Domain	Nicotinic_acetylcholine_rcpt	CHRNE CHRNG	6.16e-03	16	139	2	IPR002394
Domain	POST_SET	NSD1 EHMT2	6.16e-03	16	139	2	PS50868
Domain	ZF_RING_1	TRIM49 TRIM49C TRIM27 SH3RF2 NFX1 TRIM49B RNF111	6.17e-03	291	139	7	PS00518
Domain	MMR_HSR1	ERAL1 GNL2	6.95e-03	17	139	2	PF01926
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	USP34 STK36 ZNF48 RPS6KA2 NOB1 NSD1 GRID1 PARVB HUWE1 BIRC6 ESRP2 RHPN1 URB1 EIF4ENIF1 NBEAL2 SCN5A NFX1 ZNF398 LRP4 WDFY3 PLEC SPEN AP3D1	2.56e-10	1105	146	23	35748872
Pubmed	Identification of a genomic reservoir for new TRIM genes in primate genomes.	TRIM49 TRIM49C TRIM49D1 TRIM49B	1.10e-06	19	146	4	22144910
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	USP34 BAG3 ZNF318 HUWE1 BIRC6 JMJD1C SALL1 EIF4ENIF1 EHMT2 DIAPH3 PLEC	1.70e-06	418	146	11	34709266
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PPAN ZNF48 PKP4 RBM26 NSD1 ZNF318 TRIM27 GATAD2B BLVRB AURKA URB1 EIF4ENIF1 IGFBP5 EHMT2 FGD4 PLEKHG3 NFX1 GNL2 NUMB SPEN	4.85e-06	1497	146	20	31527615
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	RBM26 ZNF318 JMJD1C EIF4ENIF1 ROBO1 DIAPH3 PLEC AP3D1	1.36e-05	256	146	8	33397691
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RPS6KA2 TRPM2 PRR5 ARHGEF38 PARVB PATL1 HUWE1 H6PD SELENON ADCY1 JMJD1C GALNT18 PLEKHG4B SHC2 PLEKHG3 NUP210 NUMB ARHGAP8 MTARC1	1.62e-05	1489	146	19	28611215
Pubmed	The sodium leak channel, NALCN, in health and disease.	NALCN UNC80	1.75e-05	2	146	2	24904279
Pubmed	Cardiac Involvement in LAMA2-Related Muscular Dystrophy and SELENON-Related Congenital Myopathy: A Case Series.	LAMA2 SELENON	1.75e-05	2	146	2	39177608
Pubmed	Calcitonin induces dephosphorylation of Pyk2 and phosphorylation of focal adhesion kinase in osteoclasts.	CALCA PTK2B	1.75e-05	2	146	2	12231407
Pubmed	Bipolar disorder with binge eating behavior: a genome-wide association study implicates PRR5-ARHGAP8.	PRR5 ARHGAP8	1.75e-05	2	146	2	29391396
Pubmed	Escobar syndrome is a prenatal myasthenia caused by disruption of the acetylcholine receptor fetal gamma subunit.	CHRNE CHRNG	1.75e-05	2	146	2	16826520
Pubmed	Identification and characterization of a gene encoding a putative mouse Rho GTPase activating protein gene 8, Arhgap8.	PRR5 ARHGAP8	1.75e-05	2	146	2	12559566
Pubmed	UNC80 mutation causes a syndrome of hypotonia, severe intellectual disability, dyskinesia and dysmorphism, similar to that caused by mutations in its interacting cation channel NALCN.	NALCN UNC80	1.75e-05	2	146	2	26545877
Pubmed	CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels.	CLPP ERAL1	1.75e-05	2	146	2	27797820
Pubmed	Primary structure of the human muscle acetylcholine receptor. cDNA cloning of the gamma and epsilon subunits.	CHRNE CHRNG	1.75e-05	2	146	2	7688301
Pubmed	The MN1 oncoprotein activates transcription of the IGFBP5 promoter through a CACCC-rich consensus sequence.	IGFBP5 MN1	1.75e-05	2	146	2	17242174
Pubmed	Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80.	NALCN UNC80	1.75e-05	2	146	2	19092807
Pubmed	Congenital myasthenic syndrome associated with epidermolysis bullosa caused by homozygous mutations in PLEC1 and CHRNE.	CHRNE PLEC	1.75e-05	2	146	2	21175599
Pubmed	Asymmetric transmitter binding sites of fetal muscle acetylcholine receptors shape their synaptic response.	CHRNE CHRNG	1.75e-05	2	146	2	23898191
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	MOK PKP4 PARVB SORBS1 JMJD1C B4GALT5 VPS13D KANK1 SPRY4 WDFY3 WASF1	1.77e-05	536	146	11	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	MOK PKP4 PARVB SORBS1 JMJD1C B4GALT5 VPS13D KANK1 SPRY4 WDFY3 WASF1	1.83e-05	538	146	11	10512203
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 AARS1 NSD1 ELP1 ZNF318 HUWE1 BIRC6 URB1 NUP210 GNL2 PLEC SPEN	2.17e-05	653	146	12	22586326
Pubmed	Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.	TRIM49 TRIM49C TRIM49B	3.18e-05	15	146	3	19703589
Pubmed	The familial dysautonomia disease gene IKBKAP is required in the developing and adult mouse central nervous system.	CALCA ELP1 NOS1	3.18e-05	15	146	3	28167615
Pubmed	Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8.	UGT2A1 UGT2B15	5.24e-05	3	146	2	12376738
Pubmed	Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel Complex, Cause Autosomal-Recessive Severe Infantile Encephalopathy.	NALCN UNC80	5.24e-05	3	146	2	26708753
Pubmed	IKAP expression levels modulate disease severity in a mouse model of familial dysautonomia.	CALCA ELP1	5.24e-05	3	146	2	22922231
Pubmed	Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies).	NALCN UNC80	5.24e-05	3	146	2	30167850
Pubmed	Prenatal development of transient receptor potential vanilloid 1-expressing primary sensory projections to sacral autonomic preganglionic neurons.	CALCA NOS1	5.24e-05	3	146	2	16973277
Pubmed	The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma.	ESRP2 RNF111	5.24e-05	3	146	2	26522722
Pubmed	FAK and PYK2 interact with SAP90/PSD-95-Associated Protein-3.	PTK2B DLGAP3	5.24e-05	3	146	2	16202977
Pubmed	A universal oligonucleotide probe for acetylcholine receptor genes. Selection and sequencing of cDNA clones for the mouse muscle beta subunit.	CHRNE CHRNG	5.24e-05	3	146	2	3782129
Pubmed	Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex.	NALCN UNC80	5.24e-05	3	146	2	21040849
Pubmed	Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex.	NALCN UNC80	5.24e-05	3	146	2	32620897
Pubmed	Caveolin-3 suppresses late sodium current by inhibiting nNOS-dependent S-nitrosylation of SCN5A.	SCN5A NOS1	5.24e-05	3	146	2	23541953
Pubmed	Analysis of a miR-148a Targetome in B Cell Central Tolerance.	NSD1 B4GALT5	5.24e-05	3	146	2	35634349
Pubmed	The acetylcholine receptor gamma-to-epsilon switch occurs in individual endplates.	CHRNE CHRNG	5.24e-05	3	146	2	15883046
Pubmed	UNC80 functions as a scaffold for Src kinases in NALCN channel function.	NALCN UNC80	5.24e-05	3	146	2	19535918
Pubmed	Divergent origins and concerted expansion of two segmental duplications on chromosome 16.	NPIPB3 NPIPB5	5.24e-05	3	146	2	11948212
Pubmed	Changes in mRNA expression of nicotinic acetylcholine receptor subunits during embryonic development of mouse masseter muscle.	CHRNE CHRNG	5.24e-05	3	146	2	12012784
Pubmed	Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3.	UGT2A3 UGT2A1	5.24e-05	3	146	2	19858781
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	USP34 AARS1 RBM26 PATL1 HUWE1 BIRC6 JMJD1C GATAD2B KANK1 EIF4ENIF1 GNL2 ROBO1	6.61e-05	733	146	12	34672954
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	USP34 IFT140 URB1 PLEKHG3 NBEAL2	8.39e-05	105	146	5	9628581
Pubmed	Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals.	CHRNE CHRNG	1.04e-04	4	146	2	22474383
Pubmed	Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H.	FGD2 FGD4	1.04e-04	4	146	2	17564959
Pubmed	The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation.	TRPM2 PTK2B	1.04e-04	4	146	2	30020827
Pubmed	Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex.	SCN5A NOS1	1.04e-04	4	146	2	18591664
Pubmed	Developmental changes in the nicotinic acetylcholine receptor in mouse tongue striated muscle.	CHRNE CHRNG	1.04e-04	4	146	2	11926244
Pubmed	Methylation of Aurora kinase A by MMSET reduces p53 stability and regulates cell proliferation and apoptosis.	AURKA EHMT2	1.04e-04	4	146	2	30013191
Pubmed	Prenatal development of peptidergic primary afferent projections to mouse lumbosacral autonomic preganglionic cell columns.	CALCA NOS1	1.04e-04	4	146	2	12888222
Pubmed	WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2.	DIAPH3 WASF1	1.04e-04	4	146	2	18516090
Pubmed	Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions.	LAMA2 HMCN2	1.04e-04	4	146	2	34504132
Pubmed	The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium.	NALCN UNC80	1.04e-04	4	146	2	32494638
Pubmed	Bipolar disorder with comorbid binge eating history: a genome-wide association study implicates APOB.	PRR5 ARHGAP8	1.74e-04	5	146	2	24882193
Pubmed	Properties of embryonic and adult muscle acetylcholine receptors transiently expressed in COS cells.	CHRNE CHRNG	1.74e-04	5	146	2	2383398
Pubmed	Inhibition of the catalytic activity of cell adhesion kinase beta by protein-tyrosine phosphatase-PEST-mediated dephosphorylation.	CALCA PTK2B	1.74e-04	5	146	2	11337490
Pubmed	Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation.	CALCA CYP2F1 IGFBP5	1.76e-04	26	146	3	27861515
Pubmed	Congenital Myasthenic Syndromes Overview	CHRNE LRP4 PLEC	1.76e-04	26	146	3	20301347
Pubmed	Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.	PKP4 SORBS1 PTK2B DLGAP3	1.86e-04	67	146	4	29254152
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	RPS6KA2 PLPPR3 GRID1 DLGAP3 NOS1 SHISA6	1.92e-04	197	146	6	36604605
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	USP34 TICRR CDS2 NOB1 NSD1 ZNF318 PATL1 HUWE1 AURKA URB1 SEPSECS ERAL1 NFX1 PLEC	2.00e-04	1084	146	14	11544199
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RPS6KA2 PKP4 NSD1 DAPK1 SORBS1 ZNF318 HUWE1 GATAD2B DLGAP3 EHMT2 WDFY3 WASF1 NOS1	2.22e-04	963	146	13	28671696
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	STK36 IFT140 SORBS1 VPS13D LRP4	2.29e-04	130	146	5	12421765
Pubmed	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	LAMA2 CHRNG SHISA6	2.44e-04	29	146	3	23396134
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	USP34 AARS1 BAG3 RBM26 ELP1 EVPL HUWE1 AURKA DLGAP3 SEPSECS ERAL1 NUP210 DIAPH3	2.48e-04	974	146	13	28675297
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	PCBP3 NOB1 PATL1 TRIM27 URB1 EIF4ENIF1 NFX1 MARF1 DIAPH3 PLEC SPEN	2.55e-04	724	146	11	36232890
Pubmed	Cell adhesion molecule L1 affects the rate of differentiation of enteric neurons in the developing gut.	CALCA NOS1	2.60e-04	6	146	2	19235728
Pubmed	Perrault Syndrome	CLPP ERAL1	2.60e-04	6	146	2	25254289
Pubmed	Distribution of transient receptor potential vanilloid 1 channel-expressing nerve fibers in mouse rectal and colonic enteric nervous system: relationship to peptidergic and nitrergic neurons.	CALCA NOS1	2.60e-04	6	146	2	20951772
Pubmed	Genetic basis of dilated cardiomyopathy.	BAG3 SCN5A	2.60e-04	6	146	2	27736720
Pubmed	Histone H2A ubiquitination inhibits the enzymatic activity of H3 lysine 36 methyltransferases.	NSD1 EHMT2	2.60e-04	6	146	2	24019522
Pubmed	The role of USP7 in the Shoc2-ERK1/2 signaling axis and Noonan-like syndrome with loose anagen hair.	HUWE1 TRIM27	2.60e-04	6	146	2	34553755
Pubmed	Evolution of nicotinic acetylcholine receptor subunits.	CHRNE CHRNG	2.60e-04	6	146	2	9580980
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	AARS1 RBM26 SORBS1 USP9Y VPS13D NBEAL2 KIF19 GNL2 AP3D1	2.65e-04	497	146	9	36774506
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP34 IFT140 PKP4 ZNF318 TRIM27 GATAD2B HMCN2 EIF4ENIF1 EHMT2 SCN5A GNL2 LRP4 WDFY3 UNC80	2.69e-04	1116	146	14	31753913
Pubmed	MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.	BAG3 BIRC6 AURKA IGFBP5 UGT2A3	3.22e-04	140	146	5	20819778
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	PKP4 CDS2 PLPPR3 SORBS1 EIF4ENIF1 WASF1	3.31e-04	218	146	6	33378226
Pubmed	Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.	PPAN JMJD1C NUP210 SPEN	3.34e-04	78	146	4	28611094
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP34 AARS1 PARVB SORBS1 HUWE1 USP9Y EHMT2 LRP4 ROBO1 LRRN2 SPARCL1 WDFY3 PLEC MPPED2 RNF111	3.47e-04	1285	146	15	35914814
Pubmed	Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.	PRR5 ARHGAP8	3.63e-04	7	146	2	22554406
Pubmed	Neuronal nitric oxide synthase expression in the mouse vomeronasal organ during prenatal development.	CALCA NOS1	3.63e-04	7	146	2	12270041
Pubmed	Development of nicotinic receptor clusters and innervation accompanying the change in muscle phenotype in the mouse esophagus.	CALCA NOS1	3.63e-04	7	146	2	9303529
Pubmed	Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites.	SORBS1 PTK2B	3.63e-04	7	146	2	15128873
Pubmed	A role for the calmodulin kinase II-related anchoring protein (αkap) in maintaining the stability of nicotinic acetylcholine receptors.	CHRNE LRP4	3.63e-04	7	146	2	22496563
Pubmed	The location and phenotype of proliferating neural-crest-derived cells in the developing mouse gut.	CALCA NOS1	3.63e-04	7	146	2	15714282
Pubmed	The origin and development of the vagal and spinal innervation of the external muscle of the mouse esophagus.	CALCA NOS1	3.63e-04	7	146	2	9853118
Pubmed	TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration.	TRPM2 PTK2B	3.63e-04	7	146	2	18542050
Pubmed	Rare De Novo Missense Variants in RNA Helicase DDX6 Cause Intellectual Disability and Dysmorphic Features and Lead to P-Body Defects and RNA Dysregulation.	PATL1 EIF4ENIF1	3.63e-04	7	146	2	31422817
Pubmed	Human chromosome 11 DNA sequence and analysis including novel gene identification.	TRIM49 TRIM49C TRIM49D1 LRP4	3.68e-04	80	146	4	16554811
Pubmed	Large-scale identification of genes implicated in kidney glomerulus development and function.	LAMA2 RHPN1 IGFBP5	3.94e-04	34	146	3	16498405
Pubmed	A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).	EHMT2 PSORS1C1	4.82e-04	8	146	2	23326239
Pubmed	Caveolin-3 deficiency causes muscle degeneration in mice.	LAMA2 NOS1	4.82e-04	8	146	2	11115849
Pubmed	Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine.	UGT2A1 UGT2B15	4.82e-04	8	146	2	10748067
Pubmed	Myenteric expression of nerve growth factor and the p75 neurotrophin receptor regulate axonal remodeling as a consequence of colonic inflammation in mice.	CALCA NOS1	4.82e-04	8	146	2	26073142
Pubmed	The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.	UGT2A1 UGT2B15	4.82e-04	8	146	2	18719240
Pubmed	Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.	SCN5A NOS1	4.82e-04	8	146	2	9412493
Pubmed	Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency.	CHRNE CHRNG	4.82e-04	8	146	2	26993635
Pubmed	The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling.	CALCA PRLH	4.82e-04	8	146	2	32723474
Pubmed	Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning.	CHRNE CHRNG	4.82e-04	8	146	2	18434415
Pubmed	Aberrant development of motor axons and neuromuscular synapses in MyoD-null mice.	CHRNE CHRNG	4.82e-04	8	146	2	12832540
Interaction	UGT2B15 interactions	UGT2A3 UGT2A1 UGT2B15	6.06e-06	6	137	3	int:UGT2B15
Cytoband	16p12.2	NPIPB4 NPIPB3 NPIPB5	2.26e-04	37	146	3	16p12.2
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM49 TRIM49C TRIM49D1 TRIM27 TRIM49B	1.44e-04	95	95	5	59
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	FGD2 ARHGEF38 FGD4 PLEKHG3	4.02e-04	66	95	4	722
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	FGD2 FGD4 WDFY3	5.68e-04	31	95	3	81
GeneFamily	Ring finger proteins	TRIM49 TRIM49C TRIM49D1 TRIM27 SH3RF2 TRIM49B RNF111	6.17e-04	275	95	7	58
GeneFamily	UDP glucuronosyltransferases	UGT2A3 UGT2A1 UGT2B15	6.24e-04	32	95	3	363
GeneFamily	EF-hand domain containing\|Plakins	EVPL PLEC	7.49e-04	8	95	2	939
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL2 WDFY3	9.60e-04	9	95	2	1230
GeneFamily	Cholinergic receptors nicotinic subunits	CHRNE CHRNG	3.12e-03	16	95	2	173
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	FGD2 PLEKHG4B FGD4 PLEKHG3 PLEKHA8	4.63e-03	206	95	5	682
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK1 CPE C8orf34 GALNT18 FREM2 KANK1 UGT2A3 DIAPH3 WDFY3	1.09e-08	186	145	9	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP34 NPIPB4 DAPK1 NPIPB3 NPIPB5 BIRC6 JMJD1C FGD4 RNF111	1.50e-08	193	145	9	779276e775cb2492e8dd36436295a536084a6415
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK1 CPE C8orf34 GALNT18 KANK1 UGT2A3 DIAPH3 WDFY3	2.04e-07	189	145	8	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PKP4 ARHGEF38 DAPK1 GALNT18 FREM2 KANK1 FGD4 MPPED2	2.49e-07	194	145	8	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PKP4 ARHGEF38 DAPK1 GALNT18 FREM2 KANK1 FGD4 MPPED2	2.69e-07	196	145	8	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CALCA C8orf34 HMCN2 LRRN2 RESP18 WASF1 PLEKHA8	1.69e-06	174	145	7	742c73c9e090848b464323cb17579b86658c6792
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CALCA C8orf34 HMCN2 LRRN2 RESP18 WASF1 PLEKHA8	1.69e-06	174	145	7	7fed9722e64c60843092f2ba71256e3043011ef6
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RPS6KA2 CPE CHRNE FREM2 IGFBP5 SH3RF2 PCDH15	1.69e-06	174	145	7	4da79da7a09ee1e345102c5331675ebcdbe56171
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SORBS1 SALL1 IGFBP5 SCN5A PCDH15 NOS1 SHISA6	1.82e-06	176	145	7	05ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCBP3 ARHGEF38 GALNT18 FREM2 KANK1 FGD4 MPPED2	2.20e-06	181	145	7	aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK1 CPE C8orf34 GALNT18 UGT2A3 DIAPH3 WDFY3	2.28e-06	182	145	7	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	MOK HUWE1 NPIPB5 BIRC6 URB1 NFX1 SPEN	2.63e-06	186	145	7	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CALCA CPE ADCY1 KCNH6 IGFBP5 NUP210 KIF19	2.63e-06	186	145	7	dfd67d67c103c942de6c8acef8d81e57a9886154
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	NSD1 HUWE1 NPIPB5 BIRC6 URB1 SPEN RNF111	3.13e-06	191	145	7	9454f642c3621370fa23640b631301346b300950
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CALCA CPE ADCY1 KCNH6 IGFBP5 NUP210 KIF19	3.47e-06	194	145	7	ccff0b5814f5de2d42720018e7f5dc5dcdafb568
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 GRID1 CPE SORBS1 LDLRAD3 NALCN SPARCL1	3.47e-06	194	145	7	ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	EVPL ADCY1 HMCN2 LRP4 WDFY3 NOS1 UNC80	3.59e-06	195	145	7	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	EVPL ADCY1 HMCN2 LRP4 WDFY3 NOS1 UNC80	3.59e-06	195	145	7	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MOK CFAP47 PLPPR3 C8orf34 PLEKHG4B RHPN1 SYT8	3.84e-06	197	145	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 PLPPR3 LDLRAD3 ADCY1 NALCN ERAL1 SPARCL1	3.84e-06	197	145	7	6806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KANK1 LRFN5 SPRY4 KIF19 PCDH15 NOS1 UNC80	4.11e-06	199	145	7	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KANK1 LRFN5 SPRY4 KIF19 PCDH15 NOS1 UNC80	4.11e-06	199	145	7	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / Treatment groups by lineage, cell group, cell type	PKP4 BAG3 CPE GALNT18 IGFBP5 ROBO1 PLEC	4.25e-06	200	145	7	b036f5e22c95a3b14391785b6e91aa183b9bc9a8
ToppCell	Macroglial-Astrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	RPS6KA2 DAPK1 CPE SORBS1 GALNT18 FGD4 SPARCL1	4.25e-06	200	145	7	941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	PKP4 BAG3 PARVB GALNT18 B4GALT5 SPRY4 SPARCL1	4.25e-06	200	145	7	6f531a418ff25b59a543800cf4bce7b72404ce08
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RPS6KA2 PKP4 PARVB GALNT18 B4GALT5 SPRY4 SPARCL1	4.25e-06	200	145	7	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	Macroglial-Astrocytes-GFAP---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CFAP47 DAPK1 CPE SORBS1 IGFBP5 SPARCL1 PLEC	4.25e-06	200	145	7	88d66550781a3c9102ff7455f5cff6fb072943cd
ToppCell	Macroglial-Astrocytes-GFAP-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CFAP47 DAPK1 CPE SORBS1 IGFBP5 SPARCL1 PLEC	4.25e-06	200	145	7	d6a059b0ef763c281c60b1ac76da6079ea822f80
ToppCell	Macroglial-Astrocytes-GFAP--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CFAP47 DAPK1 CPE SORBS1 IGFBP5 SPARCL1 PLEC	4.25e-06	200	145	7	16269fa4adb28fc6ed032bbdba8781237dd0d249
ToppCell	Macroglial-Astrocytes-GFAP----L1-2\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CFAP47 DAPK1 CPE SORBS1 IGFBP5 SPARCL1 PLEC	4.25e-06	200	145	7	c6f43bbbd5df5f2c19ae385f1a6b6a330abede2f
ToppCell	Macroglial-Astrocytes-GFAP\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CFAP47 DAPK1 CPE SORBS1 IGFBP5 SPARCL1 PLEC	4.25e-06	200	145	7	79634b1086934412ae92f259ab43554ce545008f
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP11B1 TRPM2 DPPA2 GRID1 WASF1 SHISA6	6.38e-06	139	145	6	27dd36f5ef03fa97f0fdb19fbd259cb60e7962b3
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP11B1 TRPM2 DPPA2 GRID1 WASF1 SHISA6	6.38e-06	139	145	6	2a54627947f8c6597c041f4785f8a4e52d0edfba
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CPE KANK1 HMCN2 IGFBP5 SH3RF2 SPARCL1	1.42e-05	160	145	6	8624f101828efd32cdd38a65df8d94d690720a63
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CPE KANK1 HMCN2 IGFBP5 SH3RF2 SPARCL1	1.42e-05	160	145	6	9de3dd6b9d4b51314d60b3b01f4132bcfa2dfc18
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	CDS2 DAPK1 VPS13D NALCN PCDH15 PLEC	1.47e-05	161	145	6	347edb0de10850b7d16c40945751033289289c9b
ToppCell	Basal_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	TRIM49 GALNT18 SYT8 UGT2A1 LRP4 TRIM49B	1.75e-05	166	145	6	23c04d1fba0c1733ccd0e4378fae2edde4fd0a7b
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	PKP4 CPE PTK2B IGFBP5 LRP4 SHISA6	1.88e-05	168	145	6	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	facs\|World / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BAG3 RAB20 BIRC6 MARF1 NUMB PLEC	2.07e-05	171	145	6	bb71e816dde44fda6af0ad98d979be9f8740fda6
ToppCell	facs\|World / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BAG3 RAB20 BIRC6 MARF1 NUMB PLEC	2.07e-05	171	145	6	5bcb96ed7fc15548f2dc9cf47482f890640cb39c
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	CALCA CPE ADCY1 NALCN SCN5A UNC80	2.36e-05	175	145	6	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK1 CPE C8orf34 GALNT18 UGT2A3 DIAPH3	2.36e-05	175	145	6	284fdc7a9d303636a637041846850d19d114861a
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	CALCA CPE ADCY1 NALCN SCN5A UNC80	2.36e-05	175	145	6	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK1 CPE C8orf34 GALNT18 DIAPH3 WDFY3	2.44e-05	176	145	6	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	PPAN NSD1 NPIPB3 HUWE1 NPIPB5 URB1	2.44e-05	176	145	6	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA2 HMCN2 IGFBP5 LRFN5 SPARCL1 MN1	2.52e-05	177	145	6	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	PPAN NSD1 NPIPB3 HUWE1 NPIPB5 URB1	2.52e-05	177	145	6	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CALCA PARVB ADCY1 IGFBP5 SPARCL1 MPPED2	2.52e-05	177	145	6	8e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	NPIPB11 PKP4 KANK1 EHMT2 NFX1 CFAP53	2.52e-05	177	145	6	eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	AARS1 GRID1 VPS13D NALCN MARF1 WDFY3	2.52e-05	177	145	6	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NPIPB11 PKP4 ADCK1 EHMT2 NFX1 CFAP53	2.60e-05	178	145	6	9d575902d3dbe33437c9d4200df093a741269803
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	NPIPB11 PKP4 ADCK1 EHMT2 NFX1 CFAP53	2.60e-05	178	145	6	536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	C8orf34 KANK1 SALL1 HMCN2 IGFBP5 ROBO1	2.60e-05	178	145	6	3c973aac16988e88f5677d3d695dd772ccfd6570
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	GRID1 CPE SORBS1 RAB20 LDLRAD3 SPARCL1	2.68e-05	179	145	6	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	RA-07._Pericyte\|RA / Chamber and Cluster_Paper	GRID1 ADCY1 DLGAP3 IGFBP5 SPARCL1 SHISA6	2.85e-05	181	145	6	8dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	PCBP3 CALCA CPE KCNH6 NALCN UNC80	2.94e-05	182	145	6	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LDLRAD3 FREM2 KANK1 SPRY4 PCDH15 LRP4	2.94e-05	182	145	6	8a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LDLRAD3 FREM2 KANK1 SPRY4 PCDH15 LRP4	2.94e-05	182	145	6	e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK1 CPE C8orf34 IGFBP5 DIAPH3 WDFY3	3.04e-05	183	145	6	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 GRID1 FREM2 PCDH15 ROBO1 UNC80	3.13e-05	184	145	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 GRID1 FREM2 PCDH15 ROBO1 UNC80	3.13e-05	184	145	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 GRID1 FREM2 PCDH15 ROBO1 UNC80	3.13e-05	184	145	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CPE IGFBP5 PCDH15 ROBO1 MPPED2 UNC80	3.23e-05	185	145	6	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	LAMA2 IGFBP5 PCDH15 ROBO1 SPARCL1 UNC80	3.23e-05	185	145	6	9f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell	Anterior_Cingulate_gyrus_(CgG)\|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NPIPB3 C8orf34 IGFBP5 PCDH15 ROBO1 DIAPH3	3.33e-05	186	145	6	32af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CPE IGFBP5 PCDH15 ROBO1 MPPED2 UNC80	3.43e-05	187	145	6	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PKP4 CPE SORBS1 GALNT18 SPARCL1 NOS1	3.43e-05	187	145	6	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	Differ-KC\|World / shred by cell class for mouse tongue	CYP2F1 GALNT18 ESRP2 BLVRB PTK2B ALOX12	3.43e-05	187	145	6	08f70e5103c6dd96f439f0cceda878963d26850d
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 NPIPB4 HUWE1 BIRC6 JMJD1C SPEN	3.53e-05	188	145	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	21-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	CALCA CPE ADCY1 KCNH6 IGFBP5 UNC80	3.53e-05	188	145	6	e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	PKP4 DAPK1 GALNT18 KANK1 WDFY3 MPPED2	3.64e-05	189	145	6	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CALCA CPE ADCY1 KCNH6 IGFBP5 UNC80	3.75e-05	190	145	6	40d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CALCA CPE ADCY1 KCNH6 IGFBP5 UNC80	3.75e-05	190	145	6	f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CALCA CPE ADCY1 KCNH6 IGFBP5 UNC80	3.75e-05	190	145	6	a9a705455019e28d655636de73b07540798f82e6
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	FGD2 GPR34 TRPM2 DAPK1 PTK2B MPPED2	3.86e-05	191	145	6	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DAPK1 CPE C8orf34 GALNT18 KANK1 DIAPH3	3.86e-05	191	145	6	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6KA2 PKP4 RBM26 CPE RESP18 UNC80	3.86e-05	191	145	6	3387b95a3f2445c672d407922fdce3a91eabaef8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRID1 CPE SORBS1 LDLRAD3 NALCN SPARCL1	3.97e-05	192	145	6	24e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCell	LV-08._Macrophage\|LV / Chamber and Cluster_Paper	FGD2 GPR34 TRPM2 DAPK1 PTK2B MPPED2	3.97e-05	192	145	6	7be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	RPS6KA2 ARHGEF38 USP9Y C8orf34 FREM2 KANK1	3.97e-05	192	145	6	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	Neuroendocrine\|World / Class top	CALCA CPE ADCY1 IGFBP5 RESP18 UNC80	3.97e-05	192	145	6	0199da3ef9ddb6673e9aa41f346f374838aec182
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RPS6KA2 DAPK1 PCDH15 ROBO1 NOS1 SHISA6	4.09e-05	193	145	6	d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RPS6KA2 DAPK1 PCDH15 ROBO1 NOS1 SHISA6	4.09e-05	193	145	6	3ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RPS6KA2 DAPK1 PCDH15 ROBO1 NOS1 SHISA6	4.09e-05	193	145	6	658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	FGD2 TRPM2 DAPK1 RAB20 FGD4 MPPED2	4.33e-05	195	145	6	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PKP4 ARHGEF38 DAPK1 GALNT18 KANK1 FGD4	4.33e-05	195	145	6	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6KA2 NSD1 CPE HUWE1 RESP18 UNC80	4.33e-05	195	145	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CALCA PARVB IGFBP5 SPARCL1 MPPED2 UNC80	4.33e-05	195	145	6	f7d9adadd37209ce1a38e5d621607b9c9270fed8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 GRID1 CPE SORBS1 LDLRAD3 SPARCL1	4.45e-05	196	145	6	b8759e6231e0254797d6c30930407b79440c57bb
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TICRR CALCA CHRNE KCNH6 SALL1 UNC80	4.45e-05	196	145	6	95544097577f20ed7f4144bd940471cde0617554
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF38 DAPK1 GALNT18 FREM2 KANK1 FGD4	4.45e-05	196	145	6	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CALCA TRPM2 CHRNE KCNH6 FREM2 SALL1	4.45e-05	196	145	6	72b6a68ee760599ea86cd2d712bfd17b7b4ee417
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CPE PARVB LDLRAD3 SPARCL1 MN1 NOS1	4.58e-05	197	145	6	b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA2 PLPPR3 SORBS1 LDLRAD3 NALCN SHISA6	4.58e-05	197	145	6	ee8f7def9d5af7b1e636830a4ea1da158d02f25a
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_capillary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PARVB SORBS1 GALNT18 SHC2 PCDH15 SPARCL1	4.71e-05	198	145	6	1d30a1f73b6d6d838f49751402a29c5ef54aa81f
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGEF38 DAPK1 C8orf34 FREM2 KANK1 FGD4	4.85e-05	199	145	6	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGEF38 DAPK1 C8orf34 FREM2 KANK1 FGD4	4.85e-05	199	145	6	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGEF38 DAPK1 C8orf34 FREM2 KANK1 FGD4	4.85e-05	199	145	6	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGEF38 DAPK1 C8orf34 FREM2 KANK1 FGD4	4.85e-05	199	145	6	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IFT140 PARVB SORBS1 GALNT18 SHC2 SPARCL1	4.85e-05	199	145	6	dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
Disease	free androgen index	CYP11B1 ZNF318 JMJD1C GRAMD1B GPR83 URB1 EHMT2 UGT2A1 UGT2B15 MTARC1	1.35e-05	374	141	10	EFO_0007005
Disease	liver fat measurement	PARVB PLEC SPEN MTARC1	5.33e-05	43	141	4	EFO_0010821
Disease	congenital myasthenic syndrome (implicated_via_orthology)	CHRNE CHRNG SYT8	5.71e-05	16	141	3	DOID:3635 (implicated_via_orthology)
Disease	response to bevacizumab, chemotherapy-induced hypertension	PARVB GRAMD1B	6.78e-05	3	141	2	EFO_0005942, EFO_0005943
Disease	X-linked Aarskog syndrome (implicated_via_orthology)	FGD2 FGD4	1.35e-04	4	141	2	DOID:6683 (implicated_via_orthology)
Disease	Charcot-Marie-Tooth disease type 4H (implicated_via_orthology)	FGD2 FGD4	1.35e-04	4	141	2	DOID:0110192 (implicated_via_orthology)
Disease	Charcot-Marie-Tooth disease (implicated_via_orthology)	AARS1 FGD2 FGD4	2.01e-04	24	141	3	DOID:10595 (implicated_via_orthology)
Disease	Myasthenic Syndromes, Congenital	CHRNG LRP4 PLEC	2.01e-04	24	141	3	C0751882
Disease	Perrault syndrome	CLPP ERAL1	3.36e-04	6	141	2	cv:C0685838
Disease	refractive error, age at onset, Myopia	PCBP3 LAMA2 GALNT18 LRFN5 MPPED2 SHISA6	3.42e-04	193	141	6	EFO_0004847, HP_0000545, MONDO_0004892
Disease	Acute Myeloid Leukemia, M1	NSD1 DAPK1 EHMT2 SPRY4 MN1	3.44e-04	125	141	5	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	NSD1 DAPK1 EHMT2 SPRY4 MN1	3.44e-04	125	141	5	C1879321
Disease	leucine measurement	AARS1 DAPK1 CXXC1 EIF4ENIF1	4.21e-04	73	141	4	EFO_0009770
Disease	Gonadal dysgenesis XX type deafness	CLPP ERAL1	4.69e-04	7	141	2	C0685838
Disease	heart function measurement	BAG3 SCN5A PLEC	5.73e-04	34	141	3	EFO_0004311
Disease	Muscular Dystrophy	LAMA2 SELENON	6.23e-04	8	141	2	C0026850
Disease	progression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian carcinoma	DAPK1 GRID1 MN1	8.61e-04	39	141	3	EFO_0001075, EFO_0004920, GO_0097328, MONDO_0009354
Disease	acute necrotizing pancreatitis (implicated_via_orthology)	CALCA NOS1	9.95e-04	10	141	2	DOID:0080998 (implicated_via_orthology)
Disease	urinary 6‑hydroxymelatonin sulfate to creatinine ratio	LDLRAD3 GALNT18	9.95e-04	10	141	2	EFO_0021488
Disease	refractive error	PCBP3 LAMA2 GALNT18 CHRNG ESRP2 LRFN5 SHISA6	1.01e-03	326	141	7	MONDO_0004892
Disease	Congenital muscular dystrophy	LAMA2 SELENON	1.45e-03	12	141	2	cv:C0699743
Disease	Leukemia, Myelocytic, Acute	NSD1 DAPK1 EHMT2 SPRY4 MN1	1.49e-03	173	141	5	C0023467
Disease	migraine disorder	NSD1 SORBS1 PTK2B KANK1 EHMT2 LRFN5 MPPED2	1.69e-03	357	141	7	MONDO_0005277
Disease	X-11444 measurement	BIRC6 UGT2B15	1.71e-03	13	141	2	EFO_0021237
Disease	congestive heart failure (biomarker_via_orthology)	CYP11B1 SCN5A NOS1 ALOX12	1.76e-03	107	141	4	DOID:6000 (biomarker_via_orthology)
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	CLPP ADCY1 PCDH15	1.88e-03	51	141	3	cv:CN043650
Disease	Hypermetropia, Myopia	PCBP3 RPS6KA2 LAMA2 GRAMD1B SHISA6	2.19e-03	189	141	5	HP_0000540, HP_0000545
Disease	Peripheral Nervous System Diseases	DAPK1 AURKA ALOX12	2.22e-03	54	141	3	C4721453
Disease	delta-6 desaturase measurement	GRAMD1B DIAPH3	2.29e-03	15	141	2	EFO_0007765
Disease	Polydactyly	IFT140 FREM2 SALL1 LRP4	2.44e-03	117	141	4	C0152427
Disease	isoleucine measurement	AARS1 LAMA2 EIF4ENIF1	2.46e-03	56	141	3	EFO_0009793
Disease	Myasthenic Syndromes, Congenital, Slow Channel	CHRNG LRP4	2.60e-03	16	141	2	C0751885
Disease	Inguinal hernia	IFT140 H6PD TRIM27 HMCN2 PSORS1C1 ROBO1	2.63e-03	287	141	6	HP_0000023
Disease	cortical thickness	RPS6KA2 LAMA2 LINC01548 ZNF318 JMJD1C GATAD2B SEPSECS VPS13D LRP4 ROBO1 DIAPH3 PLEC MPPED2	2.68e-03	1113	141	13	EFO_0004840
Disease	Congenital Myasthenic Syndromes, Postsynaptic	CHRNG LRP4	2.94e-03	17	141	2	C0751883
Disease	sex interaction measurement, ulcerative colitis	EHMT2 PSORS1C1	2.94e-03	17	141	2	EFO_0000729, EFO_0008343
Disease	renal cell carcinoma (is_marker_for)	MOK AURKA KANK1 ALOX12	3.37e-03	128	141	4	DOID:4450 (is_marker_for)
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	DAPK1 JMJD1C B4GALT5 ALOX12	3.66e-03	131	141	4	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	DAPK1 JMJD1C B4GALT5 ALOX12	3.66e-03	131	141	4	C4552091
Disease	Juvenile arthritis	DAPK1 JMJD1C B4GALT5 ALOX12	3.66e-03	131	141	4	C3495559
Disease	Juvenile psoriatic arthritis	DAPK1 JMJD1C B4GALT5 ALOX12	3.66e-03	131	141	4	C3714758
Disease	Congenital Myasthenic Syndromes, Presynaptic	CHRNG LRP4	3.68e-03	19	141	2	C0751884
Disease	cumulative dose response to bevacizumab	PARVB GRAMD1B	3.68e-03	19	141	2	EFO_0005944
Disease	renovascular hypertension (biomarker_via_orthology)	LAMA2 NOS1	3.68e-03	19	141	2	DOID:1591 (biomarker_via_orthology)
Disease	urate measurement	MOK USP34 NSD1 ZNF318 BIRC6 CXXC1 JMJD1C B4GALT5 LRP4 SPARCL1 MPPED2	3.89e-03	895	141	11	EFO_0004531
Disease	bipolar disorder, schizophrenia, response to lithium ion	ADCY1 GRAMD1B	4.07e-03	20	141	2	GO_0010226, MONDO_0004985, MONDO_0005090
Disease	Juvenile-Onset Still Disease	DAPK1 JMJD1C B4GALT5 ALOX12	4.08e-03	135	141	4	C0087031
Disease	cup-to-disc ratio measurement	DAPK1 PLPPR3 MTAP SALL1 PLEKHG3 PSORS1C1 MN1	4.73e-03	430	141	7	EFO_0006939

Protein segments in the cluster

Peptide	Gene	Start	Entry
RDPELPEVIHMLQHQ	PKP4	526	Q99569
IVHRNDHLPTIFMPS	ERVPABLB-1	321	P60509
QLREHHEPVMIYQPR	DAPK1	1241	P53355
LPQISHLLNHVPRQM	ADCK1	421	Q86TW2
HNPSQRPMLREVLEH	AURKA	366	O14965
QPPPHQSIIIERMHS	BIRC6	1771	Q9NR09
RMHVRPLAPAAVQDT	CHRNG	356	P07510
QILPEMPHQTDIHRS	ARHGEF38	561	Q9NXL2
HRMRFITNHSDQPPQ	GPR34	21	Q9UPC5
VPPRLQAVTDDHIRM	BLVRB	121	P30043
RSHLFPMASHPQTRI	C8orf34	81	Q49A92
MTELRQRVAHEPVAP	CDS2	1	O95674
LMPHRISSHFLQQPR	GCSAM	151	Q8N6F7
RPPEIQHFRMSDDVH	EHMT2	201	Q96KQ7
MERHQPRLHHPAQGS	DIAPH3	1	Q9NSV4
HLPVLFRHLLPMLQR	B4GALT5	176	O43286
RPHAHLRVPHLEEVM	GRAMD1B	566	Q3KR37
RTPTTHAMSPRLRHV	CHRNE	331	Q04844
LQEPHHTLEAMLRPR	AP3D1	496	O14617
AFHPQRMIISRHLPS	NPIPB3	576	Q92617
QLHPQQMIISRHLPS	NPIPB3	641	Q92617
FHPQRMIISRHLPSV	NPIPB3	661	Q92617
GRFHPQQMIISRHLP	NPIPB3	701	Q92617
PFHPQLHPQQMIISR	NPIPB3	721	Q92617
LHPQQMIISRHLPSV	NPIPB3	726	Q92617
HPQRMIISRHLPSVS	NPIPB3	746	Q92617
VVPMILQQRAERPSH	RAB20	201	Q9NX57
PMYRHRVHAQRPNLI	RBM26	446	Q5T8P6
VLLARHGRQHTIMPS	MTAP	56	Q13126
HPRAVPSNIDKMRHD	NSD1	1776	Q96L73
VQRFADIIPMNLPHR	CYP2F1	356	P24903
DIIPMNLPHRVTRDT	CYP2F1	361	P24903
KTPAFHPQRMIISRH	NPIPB12	451	F8W0I5
HPQRMIISRHLPSVS	NPIPB12	456	F8W0I5
RFHHQPMIISRHLPS	NPIPB12	496	F8W0I5
QLHPQQMIISRHLPS	NPIPB12	561	F8W0I5
FHPQRMIISRHLPSV	NPIPB12	581	F8W0I5
GRFHPQRMIISRHLP	NPIPB12	621	F8W0I5
PFHPQLHPQQMIISR	NPIPB12	641	F8W0I5
LHPQQMIISRHLPSV	NPIPB12	646	F8W0I5
PPLITRHTHEMRVLE	LRFN5	286	Q96NI6
VSVPQRIMARHLHPI	NUP210	1551	Q8TEM1
INQSRFQPPHVHMVD	MPPED2	31	Q15777
QAPMFRPDTTHLHPQ	PATL1	346	Q86TB9
LPLRVAVHSMSPCHR	LINC01548	46	A6NM66
NNLMTLPVHRLQHPV	LDLRAD3	201	Q86YD5
LHMHFSRNPKVLNPR	NOB1	306	Q9ULX3
LPMSLLHDRIRPHNL	GNL2	116	Q13823
VHFEPHMRPRRPHQI	MTARC1	181	Q5VT66
RRHFQLTVMEPPHIE	HMCN2	3491	Q8NDA2
IHPRAFHHLPQMETL	LRRN2	326	O75325
TLRSMPALHRAPVFH	JMJD1C	1196	Q15652
PIHGHLLFNNTRPVM	FREM2	1576	Q5SZK8
HRNSSPRMPHLAVAT	KCNH6	911	Q9H252
MARHSVHHQAQRPPR	FAM90A27P	1	A6NNH2
MPRESVLPHLQVQHL	EVPL	1926	Q92817
LVHHPDMPENSRVLR	ERAL1	101	O75616
LQHHMLEPVQRIPRY	FGD4	341	Q96M96
HSFPPMNRDHRRIIH	NFX1	1021	Q12986
PVTNVSPMHLQHIRE	KANK1	251	Q14678
AFHPQRMISRHLPSV	NPIPB5	576	A8MRT5
PFHPQLHPQQMIISR	NPIPB5	636	A8MRT5
LHPQQMIISRHLPSV	NPIPB5	641	A8MRT5
HPERMIISRHLPSVS	NPIPB5	661	A8MRT5
RFHPQQMIISRHLPS	NPIPB5	701	A8MRT5
QLHPQQMIISRHLPS	NPIPB5	766	A8MRT5
FHPQQMIISRHLPSV	NPIPB5	786	A8MRT5
GRFHPQRMIISRHLP	NPIPB5	826	A8MRT5
PFHPQLHPQQMIISR	NPIPB5	846	A8MRT5
LHPQQMIISRHLPSV	NPIPB5	851	A8MRT5
MPRGNLEVVHHRALV	ELP1	711	O95163
PTHARIIVRHMAAPL	LAMA2	1281	P24043
NTAHPRIISAPEMRQ	IGFBP5	171	P24593
RLNPHPNILMLHEVV	MOK	56	Q9UQ07
TIMRHHTLRQAPQPQ	GATAD2B	501	Q8WXI9
KHPIIPIHNSLERQM	PLEKHA8	201	Q96JA3
HLSRRQPDMVPLGHH	ALOX12	596	P18054
PAFHPQRMIISRHLP	NPIPB4	621	C9JG80
PFHPQLHPQQMIISR	NPIPB4	641	C9JG80
HHQPMIISRHLPSVS	NPIPB4	666	C9JG80
RFHPQRMIISRHLPS	NPIPB4	706	C9JG80
QLHPQQMIISRHLPS	NPIPB4	771	C9JG80
FHPQRMIISRHLPSV	NPIPB4	791	C9JG80
GRFHPQRMIISRHLP	NPIPB4	831	C9JG80
PFHPQLHPQQMIISR	NPIPB4	851	C9JG80
LHPQQMIISRHLPSV	NPIPB4	856	C9JG80
AVDRHQVIMHPLKPR	GPR83	166	Q9NYM4
NIPTTHPLMVRHADH	HUWE1	2511	Q7Z6Z7
LSHHPQPQFGRRMES	PCBP3	21	P57721
MHPSQHARRPEDVRT	NOS1	341	P29475
MHFRAPIRLPEHVTV	PARVB	191	Q9HBI1
LGPHQAERISDHRMP	KIF19	911	Q2TAC6
FHPQRMIISRDLPSV	NPIPB11	591	E5RHQ5
PFHPQLHPQQMIISR	NPIPB11	651	E5RHQ5
LHPQQMIISRHLPSV	NPIPB11	656	E5RHQ5
RFHPQPMIISRHLPS	NPIPB11	716	E5RHQ5
QLHPQQMIISRHLPS	NPIPB11	781	E5RHQ5
FHPQPMIISRHLPSV	NPIPB11	801	E5RHQ5
PFHPQLHPQQMIISR	NPIPB11	861	E5RHQ5
LHPQQMIISRHLPSV	NPIPB11	866	E5RHQ5
RVLDRDPPMNIHSIV	PCDH15	101	Q96QU1
IQKMEHASRLHPQEP	RESP18	126	Q5W5W9
LSTHQVLPQNIHPMR	CFAP53	491	Q96M91
LPAHVAQHFLMSNPR	ADCY1	841	Q08828
HPINPRVALRHMERC	CXXC1	491	Q9P0U4
RHLHRTRPPDTHQDM	LINC00315	66	P59091
VTDVPFQRMHAPHRA	TMEM132E-DT	41	A2RUQ5
HPRPARFADQQHMDV	DLGAP3	11	O95886
LRSIHSAMERTPPHL	GALNT18	171	Q6P9A2
IHSTRIHIMPSLNPD	CPE	146	P16870
QQVDSLHPHRMSLEP	CYP11B1	101	P15538
DVVDLLRHQPHFRMP	MARF1	1266	Q9Y4F3
VTHPHLPRALMRSTT	IGHE	301	P01854
LTLQHHMLEPVQRIP	FGD2	236	Q7Z6J4
TDAMHIPHLFVQRNP	GRID1	106	Q9ULK0
PPLHRHNVFKRHSMR	PTK2B	766	Q14289
IHPMPVHLQQRLCAE	H6PD	651	O95479
HTVVDRPQQPMTHRE	BAG3	296	O95817
THYSVHRAMPPLRVQ	SALL1	751	Q9NSC2
HRAMPPLRVQHSCPI	SALL1	756	Q9NSC2
THDNMPVRPHNFVRE	CFAP47	3151	Q6ZTR5
GCHHIPQMVSRRPLR	IFT140	746	Q96RY7
IRAPQVHSEVLMPNR	C18orf63	401	Q68DL7
RLHRHAYPEQRQDMP	DPPA2	121	Q7Z7J5
FHPQRMIISRHLPSV	NPIPB13	581	A6NJU9
PFHPQLHPQQMIISR	NPIPB13	641	A6NJU9
LHPQQMIISRHLPSV	NPIPB13	646	A6NJU9
HPQRMIISRHLPSVS	NPIPB13	666	A6NJU9
RFHPQRMIISRHLPS	NPIPB13	706	A6NJU9
IHRLENRSMHPYSEP	MN1	411	Q10571
TSLEMNNPHAIPRRH	NUMB	251	P49757
DMHSLPHVINPVESR	PIGS	296	Q96S52
DMLAHARRPIAQRHP	SYT8	361	Q8NBV8
MSHSRLQHPLTILPI	SPRY4	26	Q9C004
CRETFPQRHMRPNRH	TRIM27	56	P14373
PQRHMRPNRHLANVT	TRIM27	61	P14373
ILHRSESVLLHMPQP	TRIM49	251	P0CI25
APLHPRIVQLSHVMD	PLEKHG3	901	A1L390
LARAHARVPPAIVQM	PRR5	166	P85299
SRMRLKLVPNHHFDP	NBEAL2	1836	Q6ZNJ1
LEMSPLAPVNSHERR	SCN5A	461	Q14524
KAHRPPREMNIHRAL	SHISA6	201	Q6ZSJ9
LRREFHMQHPSTCPA	ESRP2	161	Q9H6T0
HRHLMVRLNSVGQPV	METTL22	31	Q9BUU2
RLVHRTMAQPPVHDY	RHPN1	321	Q8TCX5
QGLREEVPPILQHHM	URB1	591	O60287
EIEIMRGLRHPNIVH	STK36	51	Q9NRP7
RPAHQLHPGLVQRML	EIF4ENIF1	821	Q9NRA8
LERDHRPHVSMPQNA	CALCA	126	P01258
MSVHQIRKHAVLPPI	CLHC1	1	Q8NHS4
MRHSLPNSRIMIHQP	CLPP	166	Q16740
LIHDIPLPEHRSNTM	SENP5	371	Q96HI0
RHRLTHMEPQDFSFP	ZNF48	376	Q96MX3
PLAMHQRHFQKPVRI	TICRR	326	Q7Z2Z1
RSVSPQLNLVHMHPE	UNC80	2066	Q8N2C7
MHLRRLFTELCHPPR	WDFY3	26	Q8IZQ1
DHSLHPPLQRMFERL	WDFY3	916	Q8IZQ1
VPRDVRIMVHPHVTA	SPEN	3191	Q96T58
RIMVHPHVTAVSEQP	SPEN	3196	Q96T58
PRRRPIMSNHTATHI	AARS1	596	P49588
PAQRLHPHEVMQRME	RNF111	741	Q6ZNA4
PHRSQKMSQLHRVPF	SPEM2	161	Q0P670
PATRQVIANHHMPSI	SHC2	236	P98077
DDPARRHMTIHVPLD	PLPPR3	386	Q6T4P5
RRHRMHEQQFAHPPL	PPAN	126	Q9NQ55
HERAQEAMRRHQKPP	PLEKHG4B	621	Q96PX9
PAAPRLQMHHVAQVL	TRPM2	551	O94759
QHPMDRVLTHSELAP	SPARCL1	601	Q14515
ILHRSESVLLHMPQP	TRIM49C	251	P0CI26
SALIRHQMIHTGERP	ZNF398	496	Q8TD17
IIHRLLSMFHPRPFV	SELENON	251	Q9NZV5
PHSRRALSPEMHAVT	SORBS1	971	Q9BX66
TRPPHVNPDRLCHME	PSORS1C1	36	Q9UIG5
HRHSMEIRTPDINPA	PRLH	26	P81277
ETGHMQHQPDRRRQP	ROBO1	1281	Q9Y6N7
IARPHQIIMSPAIER	USP9Y	1976	O00507
LHPHVPGVTNLQVMR	PLEC	36	Q15149
CRMPPSHELDHQRLL	ARHGAP8	41	P85298
ILHRSESVLLHMPQP	TRIM49D1	251	C9J1S8
MRLSRIHHDQPVKPL	UGT2A3	441	Q6UWM9
ASPFRLVPNVRIHMD	SH3RF2	111	Q8TEC5
ERLLHTPHNPISLAM	SEPSECS	361	Q9HD40
MPLVKRNIDPRHLCH	WASF1	1	Q92558
ILHRSESVLLHMPQP	TRIM49B	251	A6NDI0
LHIPAVMQHIIPFRT	USP34	256	Q70CQ2
LSRIHHDQPMKPLDR	UGT2B15	446	P54855
MRLSRIHHDQPVKPL	UGT2A1	441	P0DTE4
RLPHTAALSQFHMPR	ZNF318	751	Q5VUA4
NHAMRLPPEGILHNV	VPS13D	1841	Q5THJ4
DPHQRLTAMQVLKHP	RPS6KA2	656	Q15349
LHFPMDIHTLHPQRQ	LRP4	681	O75096
ESPFRRVMHAPTLQI	NALCN	906	Q8IZF0