Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	(R)-limonene 6-monooxygenase activity	CYP2C19 CYP2C9	6.22e-05	2	158	2	GO:0052741
GeneOntologyMolecularFunction	(S)-limonene 6-monooxygenase activity	CYP2C19 CYP2C9	6.22e-05	2	158	2	GO:0018675
GeneOntologyMolecularFunction	(S)-limonene 7-monooxygenase activity	CYP2C19 CYP2C9	6.22e-05	2	158	2	GO:0018676
GeneOntologyMolecularFunction	limonene monooxygenase activity	CYP2C19 CYP2C9	6.22e-05	2	158	2	GO:0019113
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	RASGRF1 ECT2L PLEKHG2 ARHGEF11 PLEKHG6 RAPGEF3 MCF2L DOCK6 FGD6	9.58e-05	231	158	9	GO:0005085
GeneOntologyMolecularFunction	calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	SLC8A2 SLC8A3	1.86e-04	3	158	2	GO:1905060
GeneOntologyMolecularFunction	natriuretic peptide receptor activity	NPR1 NPR2	1.86e-04	3	158	2	GO:0016941
GeneOntologyMolecularFunction	arachidonate 11,12-epoxygenase activity	CYP2C19 CYP2C9	3.69e-04	4	158	2	GO:0008405
GeneOntologyMolecularFunction	linoleic acid epoxygenase activity	CYP2C19 CYP2C9	3.69e-04	4	158	2	GO:0071614
GeneOntologyMolecularFunction	fatty acid omega-1 hydroxylase activity	CYP2C19 CYP2C9	6.13e-04	5	158	2	GO:0120502
GeneOntologyMolecularFunction	long-chain fatty acid omega-1 hydroxylase activity	CYP2C19 CYP2C9	6.13e-04	5	158	2	GO:0120319
GeneOntologyMolecularFunction	arachidonate 14,15-epoxygenase activity	CYP2C19 CYP2C9	6.13e-04	5	158	2	GO:0008404
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RASGRF1 ARHGAP17 ECT2L PLEKHG2 ARHGEF11 OPHN1 TBC1D8 PLEKHG6 RAPGEF3 MCF2L DOCK6 FGD6	7.28e-04	507	158	12	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RASGRF1 ARHGAP17 ECT2L PLEKHG2 ARHGEF11 OPHN1 TBC1D8 PLEKHG6 RAPGEF3 MCF2L DOCK6 FGD6	7.28e-04	507	158	12	GO:0030695
GeneOntologyMolecularFunction	lysophosphatidic acid acyltransferase activity	MBOAT1 AGPAT3 ABHD4	8.71e-04	24	158	3	GO:0042171
GeneOntologyMolecularFunction	lysophospholipid acyltransferase activity	MBOAT1 AGPAT3 ABHD4	8.71e-04	24	158	3	GO:0071617
GeneOntologyMolecularFunction	telomerase RNA binding	TEP1 XRN1 DKC1	9.84e-04	25	158	3	GO:0070034
GeneOntologyMolecularFunction	telomerase activity	TEP1 DKC1	1.27e-03	7	158	2	GO:0003720
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor	CYP2C19 CYP2C9	1.69e-03	8	158	2	GO:0033695
GeneOntologyMolecularFunction	caffeine oxidase activity	CYP2C19 CYP2C9	1.69e-03	8	158	2	GO:0034875
GeneOntologyBiologicalProcess	mesenchyme migration	ACTA1 ACTA2 ACTC1	4.28e-06	5	157	3	GO:0090131
GeneOntologyCellularComponent	actin-based cell projection	TPRN ACTA1 ACTA2 ACTC1 NLGN1 ZSWIM6 PLEKHG6 RAPGEF3 USH2A UTRN	5.23e-05	278	158	10	GO:0098858
GeneOntologyCellularComponent	lamellipodium	CARMIL3 ACTA1 ACTA2 ACTC1 STXBP2 RAPGEF3 CSPG4 MCF2L FGD6	6.56e-05	230	158	9	GO:0030027
Domain	RhoGEF	RASGRF1 ECT2L PLEKHG2 ARHGEF11 PLEKHG6 MCF2L FGD6	1.44e-06	68	154	7	SM00325
Domain	RhoGEF	RASGRF1 ECT2L PLEKHG2 ARHGEF11 PLEKHG6 MCF2L FGD6	1.75e-06	70	154	7	PF00621
Domain	DH_2	RASGRF1 ECT2L PLEKHG2 ARHGEF11 PLEKHG6 MCF2L FGD6	1.75e-06	70	154	7	PS50010
Domain	-	RASGRF1 ECT2L PLEKHG2 ARHGEF11 PLEKHG6 MCF2L FGD6	1.93e-06	71	154	7	1.20.900.10
Domain	DH-domain	RASGRF1 ECT2L PLEKHG2 ARHGEF11 PLEKHG6 MCF2L FGD6	1.93e-06	71	154	7	IPR000219
Domain	DH_1	RASGRF1 ECT2L PLEKHG2 ARHGEF11 PLEKHG6 MCF2L	1.31e-05	63	154	6	PS00741
Domain	Calx_beta	FRAS1 SLC8A2 SLC8A3	2.99e-05	8	154	3	SM00237
Domain	ACTINS_1	ACTA1 ACTA2 ACTC1	2.99e-05	8	154	3	PS00406
Domain	Calx_beta	FRAS1 SLC8A2 SLC8A3	4.45e-05	9	154	3	IPR003644
Domain	Calx-beta	FRAS1 SLC8A2 SLC8A3	4.45e-05	9	154	3	PF03160
Domain	Actin	ACTR10 ACTA1 ACTA2 ACTC1	1.18e-04	31	154	4	IPR004000
Domain	Actin	ACTR10 ACTA1 ACTA2 ACTC1	1.18e-04	31	154	4	PF00022
Domain	ACTIN	ACTR10 ACTA1 ACTA2 ACTC1	1.18e-04	31	154	4	SM00268
Domain	Na_Ca_Ex	SLC8A2 SLC8A3	2.02e-04	3	154	2	IPR004836
Domain	ANF_RECEPTORS	NPR1 NPR2	2.02e-04	3	154	2	PS00458
Domain	Na_Ca_Ex_C-exten	SLC8A2 SLC8A3	2.02e-04	3	154	2	IPR032452
Domain	Na_Ca_ex_C	SLC8A2 SLC8A3	2.02e-04	3	154	2	PF16494
Domain	ANPR/GUC	NPR1 NPR2	2.02e-04	3	154	2	IPR001170
Domain	Actin_CS	ACTA1 ACTA2 ACTC1	2.85e-04	16	154	3	IPR004001
Domain	ACTINS_2	ACTA1 ACTA2 ACTC1	3.43e-04	17	154	3	PS00432
Domain	Ubiquitin_3	USP11 USP4	4.01e-04	4	154	2	PF14836
Domain	Ub_USP-typ	USP11 USP4	4.01e-04	4	154	2	IPR028135
Domain	Actin/actin-like_CS	ACTA1 ACTA2 ACTC1	4.10e-04	18	154	3	IPR020902
Domain	ACTINS_ACT_LIKE	ACTA1 ACTA2 ACTC1	4.83e-04	19	154	3	PS01132
Domain	NACHT	TEP1 NLRP13 NLRP5	8.63e-04	23	154	3	PS50837
Domain	NACHT_NTPase	TEP1 NLRP13 NLRP5	8.63e-04	23	154	3	IPR007111
Domain	Spectrin	DST MCF2L UTRN	8.63e-04	23	154	3	PF00435
Domain	Na_trans_cytopl	SCN1A SCN3A	9.91e-04	6	154	2	PF11933
Domain	DUSP	USP11 USP4	9.91e-04	6	154	2	PF06337
Domain	Na_trans_cytopl	SCN1A SCN3A	9.91e-04	6	154	2	IPR024583
Domain	DUSP	USP11 USP4	9.91e-04	6	154	2	SM00695
Domain	DUSP	USP11 USP4	1.38e-03	7	154	2	PS51283
Domain	-	USP11 USP4	1.38e-03	7	154	2	3.30.2230.10
Domain	Ski_Sno	DACH1 DACH2	1.38e-03	7	154	2	PF02437
Domain	-	DACH1 DACH2	1.38e-03	7	154	2	3.10.260.20
Domain	Transform_Ski	DACH1 DACH2	1.38e-03	7	154	2	IPR003380
Domain	Pept_C19_DUSP	USP11 USP4	1.38e-03	7	154	2	IPR006615
Domain	Spectrin_repeat	DST MCF2L UTRN	1.72e-03	29	154	3	IPR002017
Pathway	REACTOME_RHO_GTPASE_CYCLE	ANKFY1 USP9X ACTC1 MTMR1 ARHGAP17 PLEKHG2 ARHGEF11 COPS2 OPHN1 WDR91 DST PLEKHG6 MCF2L DOCK6	1.58e-05	450	114	14	M27078
Pathway	REACTOME_MUSCLE_CONTRACTION	NPR1 NPR2 ACTA1 ACTA2 ACTC1 SLC8A2 SLC8A3 SCN1A SCN3A	3.92e-05	203	114	9	M5485
Pathway	REACTOME_RHO_GTPASE_CYCLE	ANKFY1 USP9X ACTC1 MTMR1 ARHGAP17 PLEKHG2 ARHGEF11 COPS2 OPHN1 DST PLEKHG6 MCF2L DOCK6	5.39e-05	439	114	13	MM15595
Pathway	WP_OCTADECANOID_FORMATION_FROM_LINOLEIC_ACID	CYP2C19 CYP2C9 ALOX15	1.07e-04	12	114	3	M48064
Pathway	REACTOME_CDC42_GTPASE_CYCLE	ARHGAP17 PLEKHG2 ARHGEF11 OPHN1 MCF2L DOCK6	1.12e-04	94	114	6	MM15598
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	DNAJB11 DSC1 CILP USP11 USP9X ACTA1 ACTA2 MTMR1 HP1BP3 LRCH3 DAP3 LRPPRC PBRM1 N4BP2 ANKIB1 PSME3 RPL7A	6.26e-09	639	158	17	23443559
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DNAJB11 ANKFY1 COPG1 INPP5B ARHGAP17 ECT2L PLEKHG2 ARHGEF11 NSRP1 OPHN1 HP1BP3 LRCH3 PLEKHG6 DKC1 PSME3 MCF2L PATJ DOCK6 FGD6 UTRN	7.57e-09	916	158	20	32203420
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	DNAJB11 DSC1 COPG1 TPRN ACTA1 ACTA2 ACTC1 NSRP1 HP1BP3 LRCH3 NSUN5 LRPPRC METTL13 SF3B1 DST UTP15 TADA2B DKC1 TOP2A RPL7A	1.36e-08	949	158	20	36574265
Pubmed	Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.	ACTA1 ACTA2 ACTC1	9.20e-08	3	158	3	7780165
Pubmed	Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax.	FLT4 ACTA2 PTPRC CSPG4	9.32e-07	17	158	4	21515254
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	HPSE2 PRAMEF13 EDNRA HP1BP3 ABHD4 PBRM1 DST SCMH1 PRAMEF14 UTRN HERC4	9.44e-07	363	158	11	14691545
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DNAJB11 ANKFY1 DSC1 COPG1 USP11 ZBED5 NSUN5 LRPPRC METTL13 SF3B1 DST PSME4 UTP15 CLIC1 XRN1 ANKIB1 DKC1 PSME3 UTRN TOP2A RPL7A	9.47e-07	1353	158	21	29467282
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	HEXB DNAJB11 COPG1 USP11 USP9X ACTR10 ACTA2 ACTC1 MTMR1 AIP COPS2 DAP3 LRPPRC SF3B1 DST STXBP2 CLIC1 PATJ RPL7A	1.30e-06	1149	158	19	35446349
Pubmed	Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	9971772
Pubmed	Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	10074138
Pubmed	Virus assembly and plasma membrane domains: which came first?	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	22989508
Pubmed	HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	1540415
Pubmed	HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	11709093
Pubmed	Genetic factors associated with drug-resistance of epilepsy: relevance of stratification by patient age and aetiology of epilepsy.	CYP2C19 CYP2C9 SCN1A	1.82e-06	6	158	3	20064729
Pubmed	Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	10049817
Pubmed	Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	12009869
Pubmed	Alternative utrophin mRNAs contribute to phenotypic differences between dystrophin-deficient mice and Duchenne muscular dystrophy.	ACTA2 CSPG4 UTRN	1.82e-06	6	158	3	29772070
Pubmed	HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	23811015
Pubmed	Retroviral assembly and budding occur through an actin-driven mechanism.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	19883584
Pubmed	Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	21917091
Pubmed	HIV-1 Gag protein associates with F-actin present in microfilaments.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	8661406
Pubmed	A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	23017337
Pubmed	Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	23875777
Pubmed	Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.	ACTA1 ACTA2 ACTC1	1.82e-06	6	158	3	9841925
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	DNAJB11 USP11 ACTA1 ACTA2 DAP3 NSUN5 LRPPRC METTL13 PBRM1 SF3B1 DKC1 RPL7A	2.53e-06	486	158	12	30940648
Pubmed	The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.	ACTA1 ACTA2 ACTC1	3.18e-06	7	158	3	22535526
Pubmed	Selective targeting of ITK blocks multiple steps of HIV replication.	ACTA1 ACTA2 ACTC1	3.18e-06	7	158	3	18443296
Pubmed	The trinity of the cortical actin in the initiation of HIV-1 infection.	ACTA1 ACTA2 ACTC1	3.18e-06	7	158	3	22640593
Pubmed	HIV-1 replication from after cell entry to the nuclear periphery.	ACTA1 ACTA2 ACTC1	3.18e-06	7	158	3	17504171
Pubmed	siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.	ACTA1 ACTA2 ACTC1	3.18e-06	7	158	3	22465675
Pubmed	Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.	ACTA1 ACTA2 ACTC1	3.18e-06	7	158	3	9384381
Pubmed	A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.	ACTA1 ACTA2 ACTC1	3.18e-06	7	158	3	30289203
Pubmed	Functional proteomics mapping of a human signaling pathway.	NPR1 FLT4 TPRN YES1 ZBED5 PBRM1 SF3B1 DST PTPRC SLC12A4 ZNF41 CSPG4 UTRN	3.38e-06	591	158	13	15231748
Pubmed	Lymphatic function is required prenatally for lung inflation at birth.	FLT4 ABCA3 ACTA2 CSPG4	4.06e-06	24	158	4	24733830
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	DNAJB11 USP9X ACTA1 ACTC1 YES1 HP1BP3 LRPPRC PBRM1 SF3B1 DST STXBP2 CLIC1 NUP210 DKC1 UTRN TOP2A RPL7A	4.62e-06	1024	158	17	24711643
Pubmed	Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report.	FLT4 ACTA2 CSPG4	5.07e-06	8	158	3	19910638
Pubmed	Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.	ACTA1 ACTA2 ACTC1	5.07e-06	8	158	3	20096780
Pubmed	Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.	ACTA1 ACTA2 ACTC1	5.07e-06	8	158	3	14694110
Pubmed	Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.	ACTA1 ACTA2 ACTC1	5.07e-06	8	158	3	20147394
Pubmed	Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I.	ACTA1 ACTC1 AIP	5.07e-06	8	158	3	12721663
Pubmed	Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.	ACTA1 ACTA2 ACTC1	5.07e-06	8	158	3	23260110
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	DSC1 ACTA1 NSRP1 HP1BP3 GTF2E1 SF3B1 DST CLIC1 CYB5R3 XRN1 DKC1 PSME3 UTRN HERC4 TOP2A RPL7A	6.06e-06	934	158	16	33916271
Pubmed	Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo.	ACTA2 PTPRC CSPG4	7.57e-06	9	158	3	38395882
Pubmed	Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.	ACTA1 ACTA2 ACTC1	7.57e-06	9	158	3	10556093
Pubmed	Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.	ACTA1 ACTA2 ACTC1	7.57e-06	9	158	3	12297046
Pubmed	Msx1 and Msx2 are expressed in sub-populations of vascular smooth muscle cells.	ACTA2 PTPRC CSPG4	7.57e-06	9	158	3	18627106
Pubmed	Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.	ACTA1 ACTA2 ACTC1	7.57e-06	9	158	3	8892894
Pubmed	HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.	ACTA1 ACTA2 ACTC1	7.57e-06	9	158	3	18775311
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	GGA2 ACTR10 IFT46 PLEKHG2 AIP ARHGEF11 YES1 GSK3A AP4E1 HDAC3 STXBP2 N4BP2 XRN1 DKC1 TOP2A	8.82e-06	853	158	15	28718761
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ACTA1 ACTA2 ACTC1 HP1BP3 CCDC148 DAP3 LRPPRC SF3B1 DST STXBP2 SLC12A4 N4BP2 CSPG4 CYB5R3 XRN1 DKC1 ATP11C MCF2L TOP2A RPL7A	9.37e-06	1442	158	20	35575683
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	COPG1 USP11 USP9X HP1BP3 LRPPRC PBRM1 SF3B1 DST UTP15 NUP210 XRN1 UTRN RPL7A	9.85e-06	653	158	13	22586326
Pubmed	Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.	CYP2C19 FMO1 CYP2C9 APEH	1.02e-05	30	158	4	20529763
Pubmed	Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.	ACTA1 ACTA2 ACTC1	1.08e-05	10	158	3	1907279
Pubmed	Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment.	CYP2C19 CYP2C9 SCN1A	1.08e-05	10	158	3	20602612
Pubmed	Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.	ACTA1 ACTA2 ACTC1	1.08e-05	10	158	3	21749862
Pubmed	Non-viral cellular substrates for human immunodeficiency virus type 1 protease.	ACTA1 ACTA2 ACTC1	1.08e-05	10	158	3	1991513
Pubmed	Gelsolin activity controls efficient early HIV-1 infection.	ACTA1 ACTA2 ACTC1	1.08e-05	10	158	3	23575248
Pubmed	FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1.	FLT4 ACTA2 CSPG4	1.08e-05	10	158	3	19398761
Pubmed	Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor.	FLT4 ACTA2 CSPG4	1.08e-05	10	158	3	21282641
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	COPG1 USP11 USP9X PBRM1 SF3B1 TADA2B USP4 PSME3	1.30e-05	235	158	8	30258100
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	DNAJB11 FRAS1 POGLUT3 DYNC2H1 WFS1 USP11 APEH MTMR1 AIP YES1 NSRP1 HP1BP3 TBC1D8 DAP3 LRPPRC SF3B1 UTP15 N4BP2 NUP210 RPL7A	1.46e-05	1487	158	20	33957083
Pubmed	CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.	ACTA1 ACTA2 ACTC1	1.48e-05	11	158	3	30962377
Pubmed	N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.	ACTA1 ACTA2 ACTC1	1.48e-05	11	158	3	23294842
Pubmed	c-kit+ cells minimally contribute cardiomyocytes to the heart.	ACTA2 PTPRC CSPG4	1.48e-05	11	158	3	24805242
Pubmed	FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity.	ACTA1 ACTA2 ACTC1	1.48e-05	11	158	3	22207710
Pubmed	Quantitative proteomic analysis of lentiviral vectors using 2-DE.	ACTA1 ACTA2 ACTC1	1.48e-05	11	158	3	19639585
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	ANKFY1 DSC1 NRDC COPG1 DYNC2H1 USP11 COPS2 STAMBP LRPPRC TADA2B DKC1 ZNF770 USP4 PSME3 DEDD UTRN	1.50e-05	1005	158	16	19615732
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	DYNC2H1 USP11 ACTA2 ACTC1 APEH IFT46 MSH4 LRPPRC PBRM1 RPL7A	1.53e-05	398	158	10	35016035
Pubmed	Functional specialization of beta-arrestin interactions revealed by proteomic analysis.	ACTA1 ACTC1 ARHGAP17 ARHGEF11 YES1 SF3B1 CLIC1 DKC1 RPL7A	1.59e-05	317	158	9	17620599
Pubmed	SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.	ACTA1 ACTA2 ACTC1	1.96e-05	12	158	3	31042497
Pubmed	HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.	ACTA1 ACTA2 ACTC1	1.96e-05	12	158	3	23071112
Pubmed	Preferential involvement of Na⁺/Ca²⁺ exchanger type-1 in the brain damage caused by transient focal cerebral ischemia in mice.	SLC8A2 SLC8A3	2.05e-05	2	158	2	23137542
Pubmed	The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate.	NPR1 NPR2	2.05e-05	2	158	2	30696704
Pubmed	Na+/Ca2+ exchanger mediates cold Ca2+ signaling conserved for temperature-compensated circadian rhythms.	SLC8A2 SLC8A3	2.05e-05	2	158	2	33931447
Pubmed	Important amino acid residues that confer CYP2C19 selective activity to CYP2C9.	CYP2C19 CYP2C9	2.05e-05	2	158	2	18511451
Pubmed	Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts.	ACTA1 ACTC1	2.05e-05	2	158	2	20706863
Pubmed	Developmental expression of human hepatic CYP2C9 and CYP2C19.	CYP2C19 CYP2C9	2.05e-05	2	158	2	14634042
Pubmed	CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract.	CYP2C19 CYP2C9	2.05e-05	2	158	2	10908295
Pubmed	A role of chondroitin sulfate glycosaminoglycan binding site in alpha4beta1 integrin-mediated melanoma cell adhesion.	ITGA4 CSPG4	2.05e-05	2	158	2	9488735
Pubmed	Oxygenation mechanism in conversion of aldehyde to carboxylic acid catalyzed by a cytochrome P-450 isozyme.	CYP2C19 CYP2C9	2.05e-05	2	158	2	1847130
Pubmed	Chimeric natriuretic peptide ACNP stimulates both natriuretic peptide receptors, the NPRA and NPRB.	NPR1 NPR2	2.05e-05	2	158	2	23186809
Pubmed	Cytochromes P450 catalyze oxidation of alpha,beta-unsaturated aldehydes.	CYP2C19 CYP2C9	2.05e-05	2	158	2	17599801
Pubmed	Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms.	CYP2C19 CYP2C9	2.05e-05	2	158	2	15385837
Pubmed	[Effect of original and generic clopidogrel on prognosis in relation to different gene polymorphisms].	CYP2C19 CYP2C9	2.05e-05	2	158	2	25518510
Pubmed	Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism.	SLC8A2 SLC8A3	2.05e-05	2	158	2	19667209
Pubmed	Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.	SCN1A SCN3A	2.05e-05	2	158	2	24990319
Pubmed	Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism.	CYP2C19 CYP2C9	2.05e-05	2	158	2	15842554
Pubmed	Rapid identification of the hepatic cytochrome P450 2C19 activity using a novel and noninvasive [13C]pantoprazole breath test.	CYP2C19 CYP2C9	2.05e-05	2	158	2	19136640
Pubmed	Mouse Cyp2c expression and zonation structure in the liver begins in the early neonatal stage.	CYP2C19 CYP2C9	2.05e-05	2	158	2	35748067
Pubmed	Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development.	CYP2C19 CYP2C9	2.05e-05	2	158	2	32587777
Pubmed	A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.	ACTA1 ACTC1	2.05e-05	2	158	2	3023046
Pubmed	Genetic polymorphisms of cytochrome P450 enzymes 2C9 and 2C19 in a healthy Iranian population.	CYP2C19 CYP2C9	2.05e-05	2	158	2	17201743
Pubmed	CYP2C9 (2&3) and CYP2C19 (2&3) polymorphisms among children with nonlesional epilepsy: a single-center study.	CYP2C19 CYP2C9	2.05e-05	2	158	2	32683556
Pubmed	Evaluation of phenytoin dosage regimens based on genotyping of CYP2C subfamily in routinely treated Japanese patients.	CYP2C19 CYP2C9	2.05e-05	2	158	2	15855721
Pubmed	The effects of CYP2C9 and CYP2C19 genetic polymorphisms on the pharmacokinetics and pharmacodynamics of glipizide in Chinese subjects.	CYP2C19 CYP2C9	2.05e-05	2	158	2	19847408
Pubmed	Proteasome activators, PA28γ and PA200, play indispensable roles in male fertility.	PSME4 PSME3	2.05e-05	2	158	2	27003159
Pubmed	CYP2C9 and CYP2C19 polymorphic forms are related to increased indisulam exposure and higher risk of severe hematologic toxicity.	CYP2C19 CYP2C9	2.05e-05	2	158	2	17504998
Pubmed	Cytochrome P450 2C epoxygenases mediate photochemical stress-induced death of photoreceptors.	CYP2C19 CYP2C9	2.05e-05	2	158	2	24519941
Pubmed	Mouse liver CYP2C39 is a novel retinoic acid 4-hydroxylase. Its down-regulation offers a molecular basis for liver retinoid accumulation and fibrosis in aryl hydrocarbon receptor-null mice.	CYP2C19 CYP2C9	2.05e-05	2	158	2	14623888
Pubmed	ATP potentiates competitive inhibition of guanylyl cyclase A and B by the staurosporine analog, Gö6976: reciprocal regulation of ATP and GTP binding.	NPR1 NPR2	2.05e-05	2	158	2	21828054
Interaction	RAC1 interactions	RASGRF1 USP9X ACTA1 ACTC1 MTMR1 ARHGAP17 PLEKHG2 ITGA4 ARHGEF11 YES1 PCDH17 OPHN1 LRCH3 HDAC3 LRPPRC DST PLEKHG6 SLC12A4 CYB5R3 MCF2L DOCK6 UTRN TOP2A	6.09e-06	1063	154	23	int:RAC1
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF1 ECT2L PLEKHG2 ARHGEF11 MCF2L FGD6	3.15e-06	66	111	6	722
GeneFamily	Actins	ACTA1 ACTA2 ACTC1	4.44e-06	6	111	3	929
GeneFamily	Guanylate cyclase receptors	NPR1 NPR2	7.69e-04	7	111	2	343
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN3A	1.31e-03	9	111	2	1203
Coexpression	HE_LIM_SUN_FETAL_LUNG_C7_COL20A1_POS_SCHWANN_CELL	FRAS1 ADAMTSL1 DPY19L3 GPR17 ACTC1 UTP15	4.91e-06	72	158	6	M45791
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000	GABRB2 USP9X ITGA4 YES1 EDNRA DACH2 SCN3A ATP11C	1.22e-05	151	150	8	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	GABRB2 SZT2 USP9X ACTA1 ACTA2 DACH1 ACTC1 ITGA4 EDNRA PCDH17 TTC6 TSPAN1 SLC8A3 DST DACH2 SCN3A ATP11C PATJ	1.61e-05	806	150	18	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 NPR1 FLT4 DACH1 ITGA4 YES1 PCDH17 ATP11C	3.62e-07	187	158	8	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	facs-Heart-LA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP5B ACTA2 PLEKHG2 EDNRA PDE8B CSPG4 SCN3A NXF3	4.26e-07	191	158	8	9c5d88f0d3c834c2419ec3da74652175153ba9df
ToppCell	facs-Heart-LA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP5B ACTA2 PLEKHG2 EDNRA PDE8B CSPG4 SCN3A NXF3	4.26e-07	191	158	8	a7494191a92984e5f53610bbbedd6714e9169e1c
ToppCell	Control_saline-Endothelial-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	NPR1 FLT4 DACH1 ITGA4 PCDH17 DST MCF2L DOCK6	6.03e-07	200	158	8	e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NPR1 DACH1 ST3GAL1 YES1 PCDH17 CYB5R3 MCF2L DOCK6	6.03e-07	200	158	8	58a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCell	Control_saline-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	NPR1 FLT4 DACH1 ITGA4 PCDH17 DST MCF2L DOCK6	6.03e-07	200	158	8	3372c488a39fe812fa94e4f0564594186fea3db5
ToppCell	mild-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MBOAT1 INPP5B DACH1 YES1 SLC8A3 PATJ ALOX15	2.67e-06	171	158	7	5c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NPR1 ACTA2 HPSE2 EDNRA CSPG4 SCN3A UTRN	3.11e-06	175	158	7	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NPR1 ACTA2 HPSE2 EDNRA CSPG4 SCN3A UTRN	3.11e-06	175	158	7	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 DACH1 PLEKHG2 ITGA4 EDNRA CSPG4 UTRN	3.35e-06	177	158	7	4943d040eee0f9dceaddc7498171281d170e271f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 DACH1 PLEKHG2 ITGA4 EDNRA CSPG4 UTRN	3.35e-06	177	158	7	3f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 INPP5B ACTA2 EDNRA SLC8A2 CSPG4 SCN3A	3.61e-06	179	158	7	8da6863edc756540bb097cc7221c1408640d9bb4
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 INPP5B ACTA2 EDNRA SLC8A2 CSPG4 SCN3A	3.61e-06	179	158	7	f39c13c99a07d009cc677e363ffe089089c64916
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 PLEKHG2 EDNRA PCDH17 CSPG4 SCN3A UTRN	4.48e-06	185	158	7	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 PLEKHG2 EDNRA PCDH17 CSPG4 SCN3A UTRN	4.48e-06	185	158	7	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRB2 ACTA2 EDNRA PDE8B CSPG4 DOCK6 UTRN	4.64e-06	186	158	7	888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GABRB2 ACTA2 DACH1 EDNRA PDE8B CSPG4 DOCK6	5.34e-06	190	158	7	4eb92aef1ee868f4537483d19014d947b7684612
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GABRB2 ACTA2 DACH1 EDNRA PDE8B CSPG4 DOCK6	5.34e-06	190	158	7	7be4341e2909101d756f14031c21e705eb45e69a
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NPR1 FLT4 ADAMTSL1 TBC1D8 MCF2L DOCK6 UTRN	5.72e-06	192	158	7	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 NPR1 FLT4 DACH1 ITGA4 YES1 PCDH17	5.72e-06	192	158	7	c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ACTA2 EDNRA SLC8A2 PDE8B CSPG4 SCN3A	5.92e-06	193	158	7	1043b28503bfaa0d5a82ec358bc86cbde73ea8f2
ToppCell	LPS-antiTNF-Endothelial-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPR1 FLT4 DACH1 YES1 PCDH17 MCF2L DOCK6	5.92e-06	193	158	7	02f633b016ab19bfa65bfd0cf32f000549a62148
ToppCell	LPS-antiTNF-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPR1 FLT4 DACH1 YES1 PCDH17 MCF2L DOCK6	5.92e-06	193	158	7	5122b1ffba42de190061be34ecdc6176f84e56a3
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ACTA2 EDNRA SLC8A2 PDE8B CSPG4 SCN3A	5.92e-06	193	158	7	0266a4fdf436d83ec1d9392abba8c6ec5166970a
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMO1 COPG1 WFS1 CARMIL3 MRPL33 SF3B1 DST	6.12e-06	194	158	7	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRC8C DACH1 PCDH17 DST DACH2 MCF2L DOCK6	6.12e-06	194	158	7	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 ACTA2 DACH1 HPSE2 EDNRA DST DACH2	6.33e-06	195	158	7	d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA3 NLGN1 TTC6 PATJ UTRN NLRP13	7.10e-06	130	158	6	6434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	FRAS1 NPR1 FLT4 DACH1 ITGA4 PCDH17 DST	7.23e-06	199	158	7	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NPR1 FLT4 ADAMTSL1 YES1 PCDH17 MCF2L DOCK6	7.23e-06	199	158	7	1c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCell	Control_saline-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control_saline / Treatment groups by lineage, cell group, cell type	NPR1 DACH1 ST3GAL1 ITGA4 YES1 PCDH17 CYB5R3	7.47e-06	200	158	7	041a34080120c9f613373c20dcc366292f558040
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NPR1 FLT4 DACH1 ITGA4 YES1 PCDH17 CYB5R3	7.47e-06	200	158	7	b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NPR1 FLT4 DACH1 PCDH17 CYB5R3 MCF2L DOCK6	7.47e-06	200	158	7	89a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCell	LPS_anti-TNF-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NPR1 FLT4 DACH1 PCDH17 DST MCF2L DOCK6	7.47e-06	200	158	7	1d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCell	LPS_anti-TNF-Endothelial-Endothelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NPR1 FLT4 DACH1 PCDH17 DST MCF2L DOCK6	7.47e-06	200	158	7	60d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	HPSE2 TTC6 SGCZ SLC8A3 TMEM132D USH2A	1.04e-05	139	158	6	64c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Cpne7\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LRRIQ4 PCDH17 STXBP2 PLEKHG6 RAPGEF3 FGD6	1.55e-05	149	158	6	8638b3819193d11411df58964069fec583f617f4
ToppCell	LPS-antiTNF-Endothelial-Mes-Like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLT4 AGPAT3 METTL13 DACH2 RAPGEF3 FASTKD3	2.16e-05	158	158	6	50df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 HPSE2 TTC6 SGCZ TMEM132D USH2A	2.23e-05	159	158	6	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 HPSE2 EDNRA PCDH17 CSPG4 SCN3A	2.75e-05	165	158	6	9de841c1c95967c562720feba930246debc626fd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 HPSE2 EDNRA PCDH17 CSPG4 SCN3A	2.75e-05	165	158	6	a612a7d3a5415ecacc3df8fbff0ce498f982aad0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 HPSE2 EDNRA PCDH17 CSPG4 SCN3A	2.75e-05	165	158	6	cdc94a640ec01c6892521bcd6f0ee0a66ff23866
ToppCell	LPS-antiTNF-Endothelial-Mes-Like-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLT4 PCDH17 DACH2 RAPGEF3 FASTKD3 UTRN	2.85e-05	166	158	6	3b750d4023a0a09d86113aae5a97d84391f7b482
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA1 ACTA2 ACTC1 ECT2L HPSE2 NLGN1	2.85e-05	166	158	6	390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA1 ACTA2 ACTC1 ECT2L HPSE2 NLGN1	2.85e-05	166	158	6	9a341dc7b756252caeaac1e934384911c880a634
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF1 EXD1 TTC6 SGCZ PATJ NLRP5	2.94e-05	167	158	6	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NPR1 FLT4 SGK3 DST SCN3A UTRN	2.94e-05	167	158	6	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NPR1 FLT4 SGK3 DST SCN3A UTRN	2.94e-05	167	158	6	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NPR1 FLT4 SGK3 DST SCN3A UTRN	2.94e-05	167	158	6	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NPR1 FLT4 SGK3 DST SCN3A UTRN	2.94e-05	167	158	6	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 DSC1 AWAT1 TTC6 PATJ FGD6	3.25e-05	170	158	6	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HPSE2 EDNRA RAPGEF3 PDE8B CSPG4 ATP11C	3.71e-05	174	158	6	8393f0b43c767839c1630bcb952d62b42efc788d
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 MBOAT1 INPP5B CDKL4 NLGN1 ALOX15	3.83e-05	175	158	6	1b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCell	Pericytes-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTSL1 ACTA2 ACTC1 HPSE2 EDNRA STXBP2	3.83e-05	175	158	6	ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 MBOAT1 INPP5B CDKL4 NLGN1 ALOX15	3.83e-05	175	158	6	a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCell	Control\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 NPR1 DACH1 ITGA4 PCDH17 DACH2	4.08e-05	177	158	6	b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCell	droplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ACTA2 EDNRA SLC8A2 CSPG4 SCN3A	4.08e-05	177	158	6	dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCell	droplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL1 ACTA2 EDNRA SLC8A2 CSPG4 SCN3A	4.21e-05	178	158	6	416f85e51f45ec7949451fd47611a84e33e87245
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 WFS1 DST SCN3A DOCK6 UTRN	4.21e-05	178	158	6	ad3de3e03a401dac64431a541899445262246347
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 ACTA2 HPSE2 EDNRA CSPG4 SCN3A	4.34e-05	179	158	6	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRRC8C NPR1 FLT4 PCDH17 RAPGEF3 MCF2L	4.48e-05	180	158	6	755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPR1 FLT4 DACH1 ITGA4 YES1 PCDH17	4.48e-05	180	158	6	30cf3c7ee29694eaccb89bf8053a82037d5c9f1d
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DACH1 YES1 PCDH17 RAPGEF3 MCF2L UTRN	4.62e-05	181	158	6	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NPR1 GPR17 DACH1 YES1 PCDH17 MCF2L	4.62e-05	181	158	6	2c660fcf0404c155955b67ab2958d6e6b0e30024
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ADAMTSL1 ACTA2 PLEKHG2 ITGA4 EDNRA CSPG4	4.76e-05	182	158	6	da61e7cb2537c567968d8bd8baf537ecdff0ab18
ToppCell	droplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DACH1 YES1 PCDH17 RAPGEF3 MCF2L UTRN	4.76e-05	182	158	6	81279877b920b5a1bc991a07d3031d6458700fe3
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTA1 ACTA2 EDNRA PDE8B CSPG4 SCN3A	4.76e-05	182	158	6	c84f44391932080df31c8765e363c3dff64b2bd1
ToppCell	Cerebellum-Endothelial-MURAL\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ADAMTSL1 ACTA2 PLEKHG2 ITGA4 EDNRA CSPG4	4.76e-05	182	158	6	b2f03f61aebb5920595fed8b9d6799a09353419b
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 WFS1 DST SCN3A DOCK6 UTRN	4.91e-05	183	158	6	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	facs-Heart-RA-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTA2 PLEKHG2 EDNRA PDE8B CSPG4 SCN3A	4.91e-05	183	158	6	0f02136359787bd78146617990968baa47a65d86
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NPR1 DACH1 PCDH17 DACH2 RAPGEF3 MCF2L	4.91e-05	183	158	6	c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCell	facs-Heart-RA-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTA2 PLEKHG2 EDNRA PDE8B CSPG4 SCN3A	4.91e-05	183	158	6	2f0dcc65ad4d90ef946919b4462280fdd20c5ea0
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1-Excitatory_Neuron.Slc17a7.Parm1.Tshz2_(Deep_layer_pyramidal_cells--layer_5)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ARL9 MSH4 FBXO47 NLRP5	5.00e-05	57	158	4	d80eb5ade3c90344b67811e7f313c7d0720715f0
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	ABCA3 RASGRF1 NLGN1 TTC6 SCN1A PATJ	5.06e-05	184	158	6	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	10x5'v1-week_12-13-Endothelial-stroma-sinusoidal_EC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NPR1 FLT4 WFS1 PCDH17 CCDC148 DOCK6	5.37e-05	186	158	6	e8ead5634686ebaa6a230eea69795d923ce9939d
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 ABCA3 NLGN1 CDCP1 PATJ UTRN	5.37e-05	186	158	6	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 NLGN1 CCDC148 WDR91 TMEM132D PATJ	5.37e-05	186	158	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	facs-Heart-LA-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP5B ACTA2 EDNRA PDE8B CSPG4 SCN3A	5.53e-05	187	158	6	a12f383b02b07af32cc53a154685df8dba8fbd3f
ToppCell	facs-Heart-LA-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP5B ACTA2 EDNRA PDE8B CSPG4 SCN3A	5.53e-05	187	158	6	c40c152fa14e6afc9188549534b64ccbaded56b3
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRC8C ADAMTSL1 YES1 PCDH17 MMEL1 ATP11C	5.70e-05	188	158	6	524d1d928c9386acf20e53d31894107dd7290dc7
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPR1 FLT4 DACH1 ITGA4 YES1 PCDH17	5.70e-05	188	158	6	73f6ec915934154f435a376cb274b058ff7c5f35
ToppCell	facs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C FLT4 DACH1 PCDH17 RAPGEF3 MCF2L	5.70e-05	188	158	6	ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPR1 FLT4 PCDH17 RAPGEF3 MCF2L DOCK6	5.70e-05	188	158	6	0026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRC8C ADAMTSL1 YES1 PCDH17 MMEL1 ATP11C	5.70e-05	188	158	6	1b57995d70cf81212e8d46dfaf44dbaf9c7bc4d5
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 DACH1 PCDH17 RAPGEF3 MCF2L DOCK6	5.70e-05	188	158	6	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRC8C ADAMTSL1 YES1 PCDH17 MMEL1 ATP11C	5.70e-05	188	158	6	cd2d1f8e43c252dd8730a5758458ef63e7ffc836
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 DYNC2H1 DACH1 CCDC148 SCN3A PATJ	5.70e-05	188	158	6	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRC8C ADAMTSL1 YES1 PCDH17 MMEL1 ATP11C	5.70e-05	188	158	6	f5a2f324f3f6c5078d57130392d3f1ba74f29094
ToppCell	facs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C FLT4 DACH1 PCDH17 RAPGEF3 MCF2L	5.70e-05	188	158	6	e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCell	facs-Heart-LV-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C FLT4 DACH1 PCDH17 RAPGEF3 MCF2L	5.70e-05	188	158	6	0fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCell	5'-Airway_Nasal-Endothelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRC8C ADAMTSL1 YES1 PCDH17 MMEL1 ATP11C	5.70e-05	188	158	6	6c9d5e4014f807149328ff4eabd5e86dfe18094d
ToppCell	facs-Heart-RA-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C FLT4 YES1 RAPGEF3 MCF2L UTRN	5.87e-05	189	158	6	1be5067c1e45af7d09c1fd6955952cb9e031a3a0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 DYNC2H1 DACH1 CDCP1 CCDC148 SCN3A	5.87e-05	189	158	6	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRAS1 CARMIL3 PCDH17 SGCZ ATP11C UTRN	5.87e-05	189	158	6	f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C FLT4 YES1 RAPGEF3 MCF2L UTRN	5.87e-05	189	158	6	30dc1725d43a60017fb12d706f1f85a33de4947e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 DYNC2H1 DACH1 CDCP1 CCDC148 SCN3A	5.87e-05	189	158	6	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLT4 ADAMTSL1 DACH1 PCDH17 MCF2L DOCK6	5.87e-05	189	158	6	e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCell	Control-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPR1 DACH1 YES1 PCDH17 ATP11C MCF2L	5.87e-05	189	158	6	5d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C FLT4 PCDH17 RAPGEF3 MCF2L UTRN	5.87e-05	189	158	6	393ec5954a12d6cf67bb435dcc34ff0b14c81e9f
ToppCell	facs-Heart-LV-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8C FLT4 PCDH17 RAPGEF3 MCF2L UTRN	5.87e-05	189	158	6	bec57459ad4bab15b2532b57722549fec2e771fb
Drug	plakin	DSC1 ACTA1 ACTA2 ACTC1 COPS2 DST UTRN	1.67e-06	82	158	7	CID000018752
Disease	Moyamoya disease (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	6.80e-06	8	148	3	DOID:13099 (implicated_via_orthology)
Disease	autosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	6.80e-06	8	148	3	DOID:0110550 (implicated_via_orthology)
Disease	Baraitser-Winter syndrome 1 (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	6.80e-06	8	148	3	DOID:0081112 (implicated_via_orthology)
Disease	thoracic aortic aneurysm (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	6.80e-06	8	148	3	DOID:14004 (implicated_via_orthology)
Disease	intestinal atresia (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	1.45e-05	10	148	3	DOID:10486 (implicated_via_orthology)
Disease	patent ductus arteriosus (implicated_via_orthology)	ACTA1 ACTA2 ACTC1	1.45e-05	10	148	3	DOID:13832 (implicated_via_orthology)
Disease	Refractive Errors	RASGRF1 ACTC1	7.47e-05	3	148	2	C0034951
Disease	X-21258 measurement	CYP2C19 CYP2C9	7.47e-05	3	148	2	EFO_0800802
Disease	Ametropia	RASGRF1 ACTC1	7.47e-05	3	148	2	C1527310
Disease	heel bone mineral density, urate measurement	INPP5B ST3GAL1 TBC1D8 SGCZ PDE8B UTRN	3.24e-04	182	148	6	EFO_0004531, EFO_0009270
Disease	triacylglycerol 50:4 measurement	DACH1 MRPL33 NLGN1	4.55e-04	30	148	3	EFO_0010411
Disease	triacylglycerol 52:5 measurement	AGPAT3 DACH1 NLGN1	7.19e-04	35	148	3	EFO_0010417
Disease	triacylglycerol 52:4 measurement	AGPAT3 DACH1 NLGN1	7.82e-04	36	148	3	EFO_0010416
Disease	Myoclonic Epilepsy	HEXB SCN1A	8.79e-04	9	148	2	C0014550
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN3A	1.10e-03	10	148	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN3A	1.10e-03	10	148	2	DOID:0080422 (implicated_via_orthology)
Disease	response to hydrochlorothiazide, diastolic blood pressure change measurement	TTC6 SGCZ	1.10e-03	10	148	2	EFO_0005202, EFO_0006945
Disease	PR domain zinc finger protein 1 measurement	APEH USP4	1.33e-03	11	148	2	EFO_0801904
Disease	X-11308 measurement	CYP2C19 CYP2C9	1.33e-03	11	148	2	EFO_0800693
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN3A	1.60e-03	12	148	2	DOID:0060170 (implicated_via_orthology)
Disease	thymol sulfate measurement	CYP2C19 CYP2C9	1.60e-03	12	148	2	EFO_0021170
Disease	acute myeloid leukemia (implicated_via_orthology)	SF3B1 TOP2A	1.60e-03	12	148	2	DOID:9119 (implicated_via_orthology)
Disease	Acute kidney injury	HEXB CYP2C19 CYP2C9 RAPGEF3	1.70e-03	101	148	4	C2609414
Disease	Acute Kidney Insufficiency	HEXB CYP2C19 CYP2C9 RAPGEF3	1.70e-03	101	148	4	C1565662
Disease	Kidney Failure, Acute	HEXB CYP2C19 CYP2C9 RAPGEF3	1.70e-03	101	148	4	C0022660
Disease	body weight	ACP7 DPY19L3 RASGRF1 COPG1 INPP5B ST3GAL1 NLGN1 ZSWIM6 SGK3 TRIM66 SGCZ DACH2 SCMH1 ULK4 PATJ	1.73e-03	1261	148	15	EFO_0004338
Disease	brain ischemia (biomarker_via_orthology)	SLC8A2 SLC8A3 CSPG4 ALOX15	1.76e-03	102	148	4	DOID:2316 (biomarker_via_orthology)
Disease	lysosomal storage disease (implicated_via_orthology)	HEXB GGA2	2.86e-03	16	148	2	DOID:3211 (implicated_via_orthology)
Disease	migraine without aura, susceptibility to, 4	HPSE2 STXBP2	2.86e-03	16	148	2	MONDO_0011847
Disease	Bipolar Disorder	GABRB2 RASGRF1 WFS1 ST3GAL1 NLGN1 GSK3A PBRM1 ULK4	2.89e-03	477	148	8	C0005586
Disease	Malignant neoplasm of breast	ABCA3 DYNC2H1 ACTA2 EDNRA SGK3 DAP3 SLC8A3 PBRM1 PTPRC CLIC1 N4BP2 FASTKD3 TOP2A	3.02e-03	1074	148	13	C0006142
Disease	immature granulocyte count	ITGA4 REEP3	3.23e-03	17	148	2	EFO_0803542
Disease	matrix metalloproteinase 12 measurement	DYNC2H1 DACH1	3.63e-03	18	148	2	EFO_0010590
Disease	migraine disorder, systolic blood pressure	HPSE2 STXBP2	3.63e-03	18	148	2	EFO_0006335, MONDO_0005277
Disease	schizophrenia, inflammatory bowel disease	ZSWIM6 ITGA4	3.63e-03	18	148	2	EFO_0003767, MONDO_0005090
Disease	intrahepatic cholangiocarcinoma (is_marker_for)	TEP1 PBRM1	4.04e-03	19	148	2	DOID:4928 (is_marker_for)
Disease	alpha-tocopherol measurement	SCN3A USH2A	4.47e-03	20	148	2	EFO_0007898
Disease	muscular dystrophy (implicated_via_orthology)	SGCZ UTRN	4.93e-03	21	148	2	DOID:9884 (implicated_via_orthology)
Disease	red blood cell density measurement	POGLUT3 MRPL33 ARHGEF11 EDNRA PBRM1 DST PTPRC PDE8B CYB5R3 ULK4 HERC4	4.94e-03	880	148	11	EFO_0007978

Protein segments in the cluster

Peptide	Gene	Start	Entry
LHRTLYAKEILPKIS	CCDC148	561	Q8NFR7
TQVLIKLIKPYTRIH	COPS2	356	P61201
KLIKPYTRIHIPFIS	COPS2	361	P61201
LAPLKLVRHKKIYVF	CSPG4	1236	Q6UVK1
QSKRGILTLKYPIEH	ACTA1	61	P68133
LLAKPCYIVISKRHI	CDCP1	51	Q9H5V8
YLIIRTLGKLIPRHQ	CDKL4	211	Q5MAI5
KVPLKGCLLRTYVLH	GJA10	146	Q969M2
IVHPVKSLKLRRPLY	GPR17	161	Q13304
QSKRGILTLKYPIEH	ACTA2	61	P62736
RLTKYPLLLESIIKH	ARHGEF11	881	O15085
RLPEAKKYLHQLIAA	ARL9	101	Q6T311
LVYLERRPKVKHILK	C17orf78	81	Q8N4C9
LLHTPLIIKELSKVY	ABCA3	1376	Q99758
SIKYPDRVKHLILVD	ABHD4	156	Q8TB40
HVLLKTRRILKCSYP	ANKIB1	651	Q9P2G1
PLHLSRILKKTVYNE	EDNRA	321	P25101
HRLLIENIPDSKYVK	ECT2L	851	Q008S8
EKRKAEALLYQILPH	NPR2	826	P20594
IITRHDLLPYVTLKR	DEDD	91	O75618
ELLLKSVHLYNPKRI	DPY19L3	506	Q6ZPD9
EKRKAEALLYQILPH	NPR1	841	P16066
LHTVYTKLKRLEITP	DACH1	226	Q9UI36
LHTVYTKLKRLDISP	DACH2	106	Q96NX9
LHRLLAEIRYLVEKP	ACTR10	316	Q9NZ32
DIKHVVLYPLVAKSL	AIP	91	O00170
RKAVLALYKFHLIAP	AP4E1	186	Q9UPM8
VAIRKYIIHKYPSLE	HP1BP3	181	Q5SSJ5
RESLRKLKEIVYPSI	MTMR1	381	Q13613
ILHVKQEKPYGRLLI	REC8	526	O95072
IKYPLRLIDREIISH	CYB5R3	41	P00387
PKYIHNLLKAVEIRK	NSRP1	101	Q9H0G5
REHTILIANVKPYLK	PCDH17	1006	O14917
ASYRKINTHILKVPE	PDCD1LG2	121	Q9BQ51
RLGAIHSLVYKLPEK	OPHN1	481	O60890
RDITYEPIKVALKTH	KCTD19	356	Q17RG1
LRPHLAKVLVYELLL	NSUN5	66	Q96P11
LYIHRVTLRKLLPGV	ACP7	91	Q6ZNF0
SKTEYPLHKAIKVER	ANKFY1	216	Q9P2R3
KAYVRVLDLHKKPFL	NUP210	996	Q8TEM1
PYLRGELLKHTKLDI	NXF3	406	Q9H4D5
YKDALVLHKVLLETR	PBRM1	746	Q86U86
QLRKHIEYRLKVSLP	LRCH3	661	Q96II8
VREPKTIQLYKHLNL	FRAS1	3416	Q86XX4
KLTYVPEHIRKLQSL	LRRIQ4	386	A6NIV6
PEHIRKLQSLKELYI	LRRIQ4	391	A6NIV6
TAPLKLTYAEKLHRL	DST	666	Q03001
HLQVAPKYLSFLEKR	EXD1	211	Q8NHP7
RLHLFLLKVPAKVES	CARMIL3	51	Q8ND23
RLVLKGPDHLYLETK	ADAMTSL1	216	Q8N6G6
PIIYSIKTKEIHRAI	OR51M1	301	Q9H341
AITHKRPLVYLGLKV	PDE8B	566	O95263
IVDLHFPLALYKKLL	HERC4	811	Q5GLZ8
YLGPLLFVKLRKRHL	ALOX15	56	P16050
KYKVLPRIHDVLCKL	LRPPRC	851	P42704
LLDNPHKEPIRLRYK	GGA2	571	Q9UJY4
HLRETLPKIPYVKAI	GABRB2	291	P47870
KLKSEVVSPRYLLVR	NLRP5	416	P59047
KDQLYLHIGLKPRVK	NLGN1	621	Q8N2Q7
PLIYSLRKKDVKRAI	OR13H1	286	Q8NG92
LLYKRLIGPKVLAVH	HPSE2	446	Q8WWQ2
IKTDVHSPLKYRVLG	MMEL1	736	Q495T6
LRTVTEKIYYLKLHP	GARIN1B	166	Q96KD3
VIGILELLKYHPRVL	HDAC3	151	O15379
LEKIYELLPHITFKA	EIF4E3	191	Q8N5X7
KEGHLVKTDIPRYII	MAST1	311	Q9Y2H9
QRITKYPLLLHAVLK	PLEKHG6	311	Q3KR16
KIVIPILKYVRGEHL	DYNC2H1	1191	Q8NCM8
SRYTPQLIDLDHKLK	IFT46	86	Q9NQC8
ARHFTKAKLTIPILY	GSK3A	206	P49840
LRYALLLLLKHPEVT	CYP2C19	306	P33261
IPILEAHRDYKKLAA	DOCK6	1711	Q96HP0
YKHPDIFKDKRVLVI	FMO1	176	Q01740
THIRDYFPITILKTK	AWAT1	76	Q58HT5
IKKAYRKLALQLHPD	DNAJB11	41	Q9UBS4
QHRLAIKVKPSFLEY	MBOAT1	171	Q6ZNC8
HKLSLDSYLLKPVQR	MCF2L	756	O15068
HSRVTVAIPLKYEVK	ITGA4	761	P13612
EPDTLHTRLKYKILQ	DSC1	271	Q08554
LLLPTKERLKYIHKI	FBXO47	126	Q5MNV8
HPDAKYAKVKLIRLV	INPP5B	411	P32019
PRKCAHILTKILYLI	COPG1	41	Q9Y678
LHLISVSKLILPYVK	CCDC168	541	Q8NDH2
LRYALLLLLKHPEVT	CYP2C9	306	P11712
VLHKYIKPREKVLVI	METTL13	41	Q8N6R0
LIDTSRHYLPVKIIL	HEXB	206	P07686
RHYLPVKIILKTLDA	HEXB	211	P07686
VYPLEKLLTSHKRLV	DKC1	286	O60832
YLHSIKIVYRDLKPE	SGK3	276	Q96BR1
KVLHIPYRDSVLTKL	KIF28P	301	B7ZC32
LHRKKTLVPALYKVI	FAM126B	31	Q8IXS8
VNYLTPIKHLRKSLK	PRAMEF13	186	Q5VWM6
PIKHLRKSLKIIYLN	PRAMEF13	191	Q5VWM6
VRKPALELLHYLKNT	DAP3	101	P51398
VLTEVPAALKRLAKY	GTF2E1	6	P29083
VLHKPLDKLLIRYEK	SZT2	741	Q5T011
LILQRKIHKEPYIRE	USH2A	5061	O75445
ILINRPAKKHLELYD	UTP15	351	Q8TED0
LTLHTVKKYFLPIIE	USP9X	266	Q93008
LLLLHTRYNKIKAIP	UTRN	1836	P46939
AIHYIPKTVRKGDVL	TMEM132D	291	Q14C87
PARYVTVKTIIIKDH	TADA2B	366	Q86TJ2
REHLITLKLKAKYPA	FANCL	146	Q9NW38
VNYLTPIKHLRKSLK	PRAMEF14	186	Q5SWL7
PIKHLRKSLKIIYLN	PRAMEF14	191	Q5SWL7
TATQLLKLAHKYRPE	RPL7A	91	P62424
DYHRKALAVLEKTLP	ARHGAP17	221	Q68EM7
AFPLIIKLGKYVVRH	FASTKD3	311	Q14CZ7
KIRVKQDKILIYHPA	ST3GAL1	236	Q11201
LIYLKHTLELVDPLK	MSH4	421	O15457
PVRKIAIKILVHSLF	SCN3A	116	Q9NY46
FLLPLYVKEIHSRKD	SGCZ	86	Q96LD1
YVKEIHSRKDSPLVL	SGCZ	91	Q96LD1
LIYRKFLHPLLSSKE	REEP3	86	Q6NUK4
LTLLDHLVFKKIPYE	RASGRF1	1046	Q13972
VLLKLDEDLHVKYPR	SLC12A4	696	Q9UP95
KLGPALKLSYHIDRL	SCMH1	641	Q96GD3
PLRKIAIKILVHSLF	SCN1A	116	P35498
HLLYVAEKKRPKAES	APEH	161	P13798
YPVSKKLLQEIHSLL	BRS3	206	P32247
QSKRGILTLKYPIEH	ACTC1	61	P68032
DPSLYKHESKLVLRK	CILP	351	O75339
LPKLHIVQVVCKKYR	CLIC1	181	O00299
LVHYPESQKLLRKKA	CNGB1	1066	Q14028
LLIEYRKKLLHEFPK	ATP11C	721	Q8NB49
RAKLVSKIAKYPHVE	PSME3	186	P61289
KHYVPIKRNLSDLLE	POGLUT3	411	Q7Z4H8
IEVSEKYRLHLNLPK	PIH1D2	276	Q8WWB5
KYRLHLNLPKLIDTE	PIH1D2	281	Q8WWB5
LPHKVRKLYSALERL	RAPGEF3	776	O95398
SLPKILVVHLKRFSY	USP4	816	Q13107
LKALHINPAYIKARI	TTC6	271	Q86TZ1
VAAAKGLPVLKYHLL	AGPAT3	191	Q9NRZ7
PVLYEQLKREKLRVH	TEP1	626	Q99973
RLREKLTLLHYDPVV	MRPL33	36	O75394
LQKYSKLLPIHTLRL	PATJ	556	Q8NI35
YKLDDLVRPYVHKIL	SF3B1	561	O75533
IEKLPKHRDYKSAVI	STAMBP	71	O95630
KIKLLYRLHIPPALT	TBC1D8	916	O95759
VVKTLKEIHLAFLPY	STXBP2	126	Q15833
HKKYLSVQALEAPRL	FLT4	666	P35916
LALKHYLLKPVQRIP	FGD6	1006	Q6ZV73
HYLEVLFRIIKPRKV	XRN1	66	Q8IZH2
VRVTVKPHLLYRPLE	XRN1	1076	Q8IZH2
NKLYRVVPIRKIHAL	NRDC	426	O43847
ELLHRLLKYLEPKLT	PSME4	1481	Q14997
FLRRLGVYPTKKHLI	NSMCE3	201	Q96MG7
EKVFPSISKLKRHYL	ZNF770	481	Q6IQ21
KKTQLEHILLRPDTY	TOP2A	36	P11388
YIKARPHQSRLLKIL	ZBED5	401	Q49AG3
YRIRKPDQVKLHLPI	ZSWIM6	281	Q9HCJ5
LLSHVKVLIKERGYE	ZNF41	196	P51814
TLKKRYPTVHEIEVI	TPRN	541	Q4KMQ1
SFLLKPVQRILKYHL	PLEKHG2	231	Q9H7P9
EHKIPYVRLERLKIC	TRIM66	856	O15016
LEDIYRPTIHKLKTS	WDR91	76	A4D1P6
EPIHADILLETYKRK	PTPRC	631	P08575
PEILIIHLKRFSYTK	USP11	821	P51784
KILHLPTYSVDKLLF	ULK4	441	Q96C45
HFLTLLVVPAIKKDY	TSPAN1	116	O60635
DLPLRLKVVKYPLHA	WFS1	281	O76024
KLRHDKLVPLYAVVS	YES1	326	P07947
YIPEHIKKLTSLERL	LRRC8C	651	Q8TDW0
YQELPVTKILHSLLK	NLRP13	336	Q86W25
IYVIPAGESRKIKHL	SLC8A2	181	Q9UPR5
VYVIPDGETRKIKHL	SLC8A3	186	P57103
RIKPAVIKYLISHSF	N4BP2	1741	Q86UW6