Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	chromatin binding	CITED2 TNRC18 CEBPA HOXC13 POLR2A SMARCC1 SMARCC2 MBD6 FOXA2 HCFC1 PHC1	2.04e-06	739	51	11	GO:0003682
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAM19 ADAMTS2 ADAMTS20 ADAMTS13	2.49e-04	120	51	4	GO:0004222
GeneOntologyCellularComponent	chromatin	CITED2 CEBPA HOXC13 POLR2A SMARCC1 SMARCC2 E2F1 POU3F1 FOXA2 HCFC1 PHC1 WDR43 KLF2	6.18e-05	1480	53	13	GO:0000785
GeneOntologyCellularComponent	Rb-E2F complex	CEBPA E2F1	9.40e-05	6	53	2	GO:0035189
GeneOntologyCellularComponent	npBAF complex	SMARCC1 SMARCC2	5.63e-04	14	53	2	GO:0071564
GeneOntologyCellularComponent	brahma complex	SMARCC1 SMARCC2	5.63e-04	14	53	2	GO:0035060
GeneOntologyCellularComponent	RSC-type complex	SMARCC1 SMARCC2	6.48e-04	15	53	2	GO:0016586
GeneOntologyCellularComponent	nBAF complex	SMARCC1 SMARCC2	7.40e-04	16	53	2	GO:0071565
GeneOntologyCellularComponent	extracellular matrix	COL4A4 LAMB4 ADAM19 ADAMTS2 ADAMTS20 ADAMTS13 HCFC1	1.28e-03	656	53	7	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL4A4 LAMB4 ADAM19 ADAMTS2 ADAMTS20 ADAMTS13 HCFC1	1.30e-03	658	53	7	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL4A4 LAMB4 ADAM19 ADAMTS2 ADAMTS20 HCFC1	2.16e-03	530	53	6	GO:0062023
Domain	DISINTEGRIN_1	ADAM19 ADAMTS2 ADAMTS20 ADAMTS13	4.90e-06	40	53	4	PS00427
Domain	Reprolysin	ADAM19 ADAMTS2 ADAMTS20 ADAMTS13	4.90e-06	40	53	4	PF01421
Domain	ADAM_MEPRO	ADAM19 ADAMTS2 ADAMTS20 ADAMTS13	4.90e-06	40	53	4	PS50215
Domain	DISINTEGRIN_2	ADAM19 ADAMTS2 ADAMTS20 ADAMTS13	4.90e-06	40	53	4	PS50214
Domain	Peptidase_M12B	ADAM19 ADAMTS2 ADAMTS20 ADAMTS13	4.90e-06	40	53	4	IPR001590
Domain	Disintegrin_dom	ADAM19 ADAMTS2 ADAMTS20 ADAMTS13	5.41e-06	41	53	4	IPR001762
Domain	SMARCC_C	SMARCC1 SMARCC2	7.90e-06	2	53	2	IPR032451
Domain	SMARCC_N	SMARCC1 SMARCC2	7.90e-06	2	53	2	IPR032450
Domain	SWIRM-assoc	SMARCC1 SMARCC2	7.90e-06	2	53	2	IPR032448
Domain	SWIRM-assoc_2	SMARCC1 SMARCC2	7.90e-06	2	53	2	PF16496
Domain	SWIRM-assoc_1	SMARCC1 SMARCC2	7.90e-06	2	53	2	PF16495
Domain	SWIRM-assoc_3	SMARCC1 SMARCC2	7.90e-06	2	53	2	PF16498
Domain	Peptidase_M12B_ADAM-TS	ADAMTS2 ADAMTS20 ADAMTS13	4.19e-05	24	53	3	IPR013273
Domain	MetalloPept_cat_dom	ADAM19 ADAMTS2 ADAMTS20 ADAMTS13	8.18e-05	81	53	4	IPR024079
Domain	-	ADAM19 ADAMTS2 ADAMTS20 ADAMTS13	8.18e-05	81	53	4	3.40.390.10
Domain	SWIRM	SMARCC1 SMARCC2	1.18e-04	6	53	2	PS50934
Domain	SPOC_C	DIDO1 SPOCD1	1.18e-04	6	53	2	IPR012921
Domain	SWIRM	SMARCC1 SMARCC2	1.18e-04	6	53	2	PF04433
Domain	SWIRM	SMARCC1 SMARCC2	1.18e-04	6	53	2	IPR007526
Domain	SPOC	DIDO1 SPOCD1	1.18e-04	6	53	2	PF07744
Domain	TFS2M	DIDO1 SPOCD1	1.64e-04	7	53	2	SM00510
Domain	TFIIS_M	DIDO1 SPOCD1	1.64e-04	7	53	2	PF07500
Domain	ZINC_PROTEASE	ADAM19 ADAMTS2 ADAMTS20 ADAMTS13	1.71e-04	98	53	4	PS00142
Domain	Peptidase_M12B_N	ADAM19 ADAMTS2 ADAMTS20	1.83e-04	39	53	3	IPR002870
Domain	Pep_M12B_propep	ADAM19 ADAMTS2 ADAMTS20	1.83e-04	39	53	3	PF01562
Domain	TFIIS_cen_dom	DIDO1 SPOCD1	2.19e-04	8	53	2	IPR003618
Domain	-	DIDO1 SPOCD1	2.19e-04	8	53	2	1.10.472.30
Domain	TFIIS_CENTRAL	DIDO1 SPOCD1	2.19e-04	8	53	2	PS51321
Domain	TSP_1	ADAMTS2 ADAMTS20 ADAMTS13	7.60e-04	63	53	3	PF00090
Domain	TSP1	ADAMTS2 ADAMTS20 ADAMTS13	8.32e-04	65	53	3	SM00209
Domain	TSP1_rpt	ADAMTS2 ADAMTS20 ADAMTS13	8.32e-04	65	53	3	IPR000884
Domain	TSP1	ADAMTS2 ADAMTS20 ADAMTS13	8.32e-04	65	53	3	PS50092
Domain	EGF-like_CS	JAG2 LAMB4 ADAM19 VWCE EPHA10	8.51e-04	261	53	5	IPR013032
Domain	EGF_2	JAG2 LAMB4 ADAM19 VWCE EPHA10	9.11e-04	265	53	5	PS01186
Domain	VWC_out	JAG2 VWCE	1.31e-03	19	53	2	SM00215
Domain	FN3	LRFN3 FNDC4 HCFC1 EPHA10	1.87e-03	185	53	4	SM00060
Domain	ADAM_spacer1	ADAMTS2 ADAMTS20	1.92e-03	23	53	2	IPR010294
Domain	ADAM_spacer1	ADAMTS2 ADAMTS20	1.92e-03	23	53	2	PF05986
Domain	FN3	LRFN3 FNDC4 HCFC1 EPHA10	2.44e-03	199	53	4	PS50853
Domain	SANT_dom	SMARCC1 SMARCC2	2.46e-03	26	53	2	IPR017884
Domain	ACR	ADAM19 ADAMTS13	2.65e-03	27	53	2	SM00608
Domain	ADAM_Cys-rich	ADAM19 ADAMTS13	2.65e-03	27	53	2	IPR006586
Domain	SANT	SMARCC1 SMARCC2	2.85e-03	28	53	2	PS51293
Domain	BRCT_dom	SMARCC1 SMARCC2	2.85e-03	28	53	2	IPR001357
Domain	FN3_dom	LRFN3 FNDC4 HCFC1 EPHA10	2.91e-03	209	53	4	IPR003961
Domain	-	SMARCC1 SMARCC2 E2F1 FOXA2	3.38e-03	218	53	4	1.10.10.10
Domain	Chromo/shadow_dom	SMARCC1 SMARCC2	3.94e-03	33	53	2	IPR000953
Domain	CHROMO	SMARCC1 SMARCC2	3.94e-03	33	53	2	SM00298
Domain	Myb_DNA-binding	SMARCC1 SMARCC2	4.43e-03	35	53	2	PF00249
Domain	VWFC_1	JAG2 VWCE	4.68e-03	36	53	2	PS01208
Domain	WHTH_DNA-bd_dom	SMARCC1 SMARCC2 E2F1 FOXA2	4.90e-03	242	53	4	IPR011991
Domain	VWC	JAG2 VWCE	5.20e-03	38	53	2	SM00214
Domain	MYB_LIKE	SMARCC1 SMARCC2	5.20e-03	38	53	2	PS50090
Domain	VWFC_2	JAG2 VWCE	5.20e-03	38	53	2	PS50184
Pathway	KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119	MBD6 HCFC1 PHC1	6.55e-05	26	43	3	M47923
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	SMARCC1 SMARCC2 PHC1	1.48e-04	34	43	3	MM15531
Pathway	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN	SMARCC1 SMARCC2 PHC1	1.91e-04	37	43	3	M27797
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS2 ADAMTS20 ADAMTS13	2.24e-04	39	43	3	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS2 ADAMTS20 ADAMTS13	2.24e-04	39	43	3	MM15165
Pubmed	Placing the HIRA histone chaperone complex in the chromatin landscape.	POLR2A SMARCC1 SMARCC2 E2F1	1.71e-07	31	55	4	23602572
Pubmed	Critical role of the BAF chromatin remodeling complex during murine neural crest development.	SMARCC1 SMARCC2 E2F1	2.08e-07	8	55	3	33750945
Pubmed	Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors.	SMARCC1 SMARCC2 HCFC1 PHC1	2.83e-07	35	55	4	22325351
Pubmed	Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling.	POLR2A SMARCC1 SMARCC2	3.12e-07	9	55	3	9845365
Pubmed	Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes.	POLR2A SMARCC1 SMARCC2	4.46e-07	10	55	3	11238380
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS2 ADAMTS20 ADAMTS13	8.15e-07	12	55	3	25770910
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	JAG2 GAS2L1 MYOF TNRC18 ARHGEF40 POLR2A MBD6 MYRF ANKRD33B HCFC1 ZNF503	1.05e-06	1105	55	11	35748872
Pubmed	Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.	POLR2A SMARCC1 SMARCC2	1.35e-06	14	55	3	8895581
Pubmed	A human RNA polymerase II complex containing factors that modify chromatin structure.	POLR2A SMARCC1 SMARCC2	2.07e-06	16	55	3	9710619
Pubmed	The Swi3 protein plays a unique role in regulating respiration in eukaryotes.	SMARCC1 SMARCC2	2.46e-06	2	55	2	27190130
Pubmed	BQ788 reveals glial ETB receptor modulation of neuronal cholinergic and nitrergic pathways to inhibit intestinal motility: Linked to postoperative ileus.	POLR2A E2F1	2.46e-06	2	55	2	37198101
Pubmed	Functional Intraregional and Interregional Heterogeneity between Myenteric Glial Cells of the Colon and Duodenum in Mice.	POLR2A E2F1	2.46e-06	2	55	2	36319118
Pubmed	The transcriptional co-regulator HCF-1 is required for INS-1 β-cell glucose-stimulated insulin secretion.	E2F1 HCFC1	2.46e-06	2	55	2	24250814
Pubmed	Circuit-specific enteric glia regulate intestinal motor neurocircuits.	POLR2A E2F1	2.46e-06	2	55	2	34593632
Pubmed	E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.	CEBPA E2F1	2.46e-06	2	55	2	11672531
Pubmed	Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain.	CITED2 E2F1 POU3F1 ZNF503	2.56e-06	60	55	4	35175194
Pubmed	Components of the human SWI/SNF complex are enriched in active chromatin and are associated with the nuclear matrix.	POLR2A SMARCC1 SMARCC2	4.19e-06	20	55	3	9128241
Pubmed	Cited2 is required for fetal lung maturation.	CITED2 CEBPA FOXA2	5.64e-06	22	55	3	18358466
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS2 ADAMTS20 ADAMTS13 FOXA2	6.26e-06	75	55	4	20637190
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	POLR2A SMARCC1 SMARCC2 HCFC1 PHC1	6.89e-06	167	55	5	20362541
Pubmed	Location of the velvet coat mutant in linkage group VI of the mouse.	HOXC13 ADAMTS20	7.36e-06	3	55	2	5075903
Pubmed	An emerging model for BAP1's role in regulating cell cycle progression.	E2F1 HCFC1	7.36e-06	3	55	2	21484256
Pubmed	Wwp2-mediated ubiquitination of the RNA polymerase II large subunit in mouse embryonic pluripotent stem cells.	POLR2A SMARCC1	7.36e-06	3	55	2	17526739
Pubmed	E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases.	E2F1 HCFC1	7.36e-06	3	55	2	19763085
Pubmed	C/EBPalpha is required for lung maturation at birth.	CEBPA FOXA2	7.36e-06	3	55	2	16467360
Pubmed	Unusual recombination values and the mapping of the lethal miniature in the house mouse.	HOXC13 ADAMTS20	7.36e-06	3	55	2	4670053
Pubmed	Regulation of Trib2 by an E2F1-C/EBPα feedback loop in AML cell proliferation.	CEBPA E2F1	7.36e-06	3	55	2	24516045
Pubmed	The pro-death role of Cited2 in stroke is regulated by E2F1/4 transcription factors.	CITED2 E2F1	7.36e-06	3	55	2	30967472
Pubmed	Alterations in BAP1 Are Associated with Cisplatin Resistance through Inhibition of Apoptosis in Malignant Pleural Mesothelioma.	E2F1 HCFC1	7.36e-06	3	55	2	33547197
Pubmed	BAF chromatin remodeling complex: cortical size regulation and beyond.	SMARCC1 SMARCC2	7.36e-06	3	55	2	23974113
Pubmed	LPAR1 regulates enteric nervous system function through glial signaling and contributes to chronic intestinal pseudo-obstruction.	POLR2A E2F1	7.36e-06	3	55	2	35166239
Pubmed	Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1).	E2F1 HCFC1	1.47e-05	4	55	2	23629655
Pubmed	XPC is an RNA polymerase II cofactor recruiting ATAC to promoters by interacting with E2F1.	POLR2A E2F1	1.47e-05	4	55	2	29973595
Pubmed	Host cell factor-1 recruitment to E2F-bound and cell-cycle-control genes is mediated by THAP11 and ZNF143.	E2F1 HCFC1	1.47e-05	4	55	2	25437553
Pubmed	Identification of a secondary promoter of CASP8 and its related transcription factor PURα.	POLR2A E2F1	1.47e-05	4	55	2	24819879
Pubmed	Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression.	POLR2A HCFC1	1.47e-05	4	55	2	30955890
Pubmed	Expression of ADAMTS-2, -3, -13, and -14 in culprit coronary lesions in patients with acute myocardial infarction or stable angina.	ADAMTS2 ADAMTS13	1.47e-05	4	55	2	22205175
Pubmed	Mammalian chromatin remodeling complex SWI/SNF is essential for enhanced expression of the albumin gene during liver development.	CEBPA SMARCC1	1.47e-05	4	55	2	16452305
Pubmed	The tumor suppressor hSNF5/INI1 modulates cell growth and actin cytoskeleton organization.	SMARCC1 SMARCC2	1.47e-05	4	55	2	15150092
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	CITED2 CEBPA SMARCC1 DIDO1 E2F1 POU3F1 PHC1 KLF2	1.50e-05	709	55	8	22988430
Pubmed	Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome.	SMARCC1 SMARCC2	2.45e-05	5	55	2	9693044
Pubmed	Regulating SWI/SNF subunit levels via protein-protein interactions and proteasomal degradation: BAF155 and BAF170 limit expression of BAF57.	SMARCC1 SMARCC2	2.45e-05	5	55	2	16199878
Pubmed	Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes.	SMARCC1 SMARCC2	2.45e-05	5	55	2	12244326
Pubmed	Members of the hSWI/SNF chromatin remodeling complex associate with and are phosphorylated by protein kinase B/Akt.	SMARCC1 SMARCC2	2.45e-05	5	55	2	16568092
Pubmed	The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activation in vivo.	SMARCC1 SMARCC2	2.45e-05	5	55	2	18086889
Pubmed	p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes.	SMARCC1 SMARCC2	2.45e-05	5	55	2	9584200
Pubmed	Identification and characterization of a 315-base pair enhancer, located more than 55 kilobases 5' of the apolipoprotein B gene, that confers expression in the intestine.	CEBPA FOXA2	2.45e-05	5	55	2	10859308
Pubmed	DIDO as a Switchboard that Regulates Self-Renewal and Differentiation in Embryonic Stem Cells.	POLR2A DIDO1	2.45e-05	5	55	2	28330622
Pubmed	IL-17 inhibits adipogenesis in part via C/EBPα, PPARγ and Krüppel-like factors.	CEBPA KLF2	2.45e-05	5	55	2	23332504
Pubmed	Transcription Factor KLF2 in Dendritic Cells Downregulates Th2 Programming via the HIF-1α/Jagged2/Notch Axis.	JAG2 KLF2	2.45e-05	5	55	2	27302755
Pubmed	Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.	POU3F1 ADARB2 ZNF503	3.55e-05	40	55	3	27657450
Pubmed	PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression.	E2F1 HCFC1	3.67e-05	6	55	2	20622854
Pubmed	Variations in the composition of mammalian SWI/SNF chromatin remodelling complexes.	SMARCC1 SMARCC2	3.67e-05	6	55	2	19650111
Pubmed	Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.	SMARCC1 SMARCC2	3.67e-05	6	55	2	16940996
Pubmed	The BRCT domain is a phospho-protein binding domain.	POLR2A E2F1	3.67e-05	6	55	2	14576433
Pubmed	Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression.	SMARCC1 SMARCC2	3.67e-05	6	55	2	21095589
Pubmed	FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination.	ATAD3B SMARCC2	3.67e-05	6	55	2	37348029
Pubmed	The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.	SMARCC1 SMARCC2	3.67e-05	6	55	2	16230384
Pubmed	Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes.	CEBPA E2F1	3.67e-05	6	55	2	20176812
Pubmed	BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer.	SMARCC1 SMARCC2	3.67e-05	6	55	2	10943845
Pubmed	Varying modulation of HIV-1 LTR activity by Baf complexes.	SMARCC1 SMARCC2	3.67e-05	6	55	2	21699904
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	CITED2 CEBPA SMARCC1 DIDO1 E2F1 POU3F1 PHC1 KLF2	3.80e-05	808	55	8	20412781
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	GOPC ADRM1 SMARCC1 SMARCC2 HCFC1 ZNF503	3.96e-05	399	55	6	35987950
Pubmed	Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter.	SMARCC1 SMARCC2	5.13e-05	7	55	2	16601680
Pubmed	BRIT1/MCPH1 links chromatin remodelling to DNA damage response.	SMARCC1 SMARCC2	5.13e-05	7	55	2	19525936
Pubmed	Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation.	CEBPA E2F1	5.13e-05	7	55	2	30109252
Pubmed	Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes.	SMARCC1 SMARCC2	5.13e-05	7	55	2	28369036
Pubmed	Target genes of the largest human SWI/SNF complex subunit control cell growth.	SMARCC1 SMARCC2	5.13e-05	7	55	2	21118156
Pubmed	Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development.	CEBPA FOXA2	5.13e-05	7	55	2	20842632
Pubmed	Proapoptotic function of the retinoblastoma tumor suppressor protein.	POLR2A E2F1	5.13e-05	7	55	2	19249677
Pubmed	E2F activation of S phase promoters via association with HCF-1 and the MLL family of histone H3K4 methyltransferases.	E2F1 HCFC1	5.13e-05	7	55	2	17612494
Pubmed	CHD7 cooperates with PBAF to control multipotent neural crest formation.	SMARCC1 SMARCC2	6.83e-05	8	55	2	20130577
Pubmed	CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner.	POLR2A E2F1	6.83e-05	8	55	2	20106982
Pubmed	The assembly of mammalian SWI/SNF chromatin remodeling complexes is regulated by lysine-methylation dependent proteolysis.	SMARCC1 SMARCC2	6.83e-05	8	55	2	36335117
Pubmed	Epigenetic regulation by BAF (mSWI/SNF) chromatin remodeling complexes is indispensable for embryonic development.	SMARCC1 SMARCC2	6.83e-05	8	55	2	26986003
Pubmed	The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid-inducible gene-I-like receptor signalling and is a potential prognostic biomarker for colon cancer.	SMARCC1 SMARCC2	6.83e-05	8	55	2	28940253
Pubmed	Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord.	CACNA1I FOXA2	6.83e-05	8	55	2	34478646
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	SMARCC1 SMARCC2 DIDO1 ADARB2 HCFC1	7.00e-05	271	55	5	32433965
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	POLR2A GART SMARCC1 SMARCC2 DIDO1 HCFC1 WDR43	7.40e-05	653	55	7	22586326
Pubmed	Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B.	SMARCC1 SMARCC2	8.78e-05	9	55	2	20086098
Pubmed	Mutation of the HEXIM1 gene results in defects during heart and vascular development partly through downregulation of vascular endothelial growth factor.	CEBPA POLR2A	8.78e-05	9	55	2	18079413
Pubmed	The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds.	SMARCC1 SMARCC2	8.78e-05	9	55	2	37805104
Pubmed	EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear.	SMARCC1 SMARCC2	8.78e-05	9	55	2	22513373
Pubmed	Quantitative gene expression profiling reveals a fetal hepatic phenotype of murine ES-derived hepatocytes.	CEBPA FOXA2	1.10e-04	10	55	2	15005571
Pubmed	Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway.	SMARCC1 SMARCC2	1.10e-04	10	55	2	16751102
Pubmed	Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes.	POLR2A HCFC1	1.10e-04	10	55	2	17998332
Pubmed	Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.	SMARCC1 SMARCC2	1.10e-04	10	55	2	12665591
Pubmed	A methylation-mediator complex in hormone signaling.	SMARCC1 SMARCC2	1.10e-04	10	55	2	14729568
Pubmed	Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance.	SMARCC1 SMARCC2	1.10e-04	10	55	2	34716243
Pubmed	ADAMTS: a novel family of extracellular matrix proteases.	ADAMTS2 ADAMTS13	1.10e-04	10	55	2	11167130
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	SMARCC1 SMARCC2 MBD6 PHC1	1.14e-04	157	55	4	30186101
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ATAD3B HOXC13 POLR2A SMARCC1 SMARCC2 DIDO1 HCFC1 WDR43	1.21e-04	954	55	8	36373674
Pubmed	A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.	SMARCC1 SMARCC2 HCFC1	1.26e-04	61	55	3	20305087
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	DIDO1 E2F1 MBD6 HCFC1 PHC1 ZNF503	1.30e-04	495	55	6	27705803
Pubmed	Functional selectivity of recombinant mammalian SWI/SNF subunits.	SMARCC1 SMARCC2	1.34e-04	11	55	2	11018012
Pubmed	mTORC1 activity is essential for erythropoiesis and B cell lineage commitment.	CEBPA KLF2	1.34e-04	11	55	2	31729420
Pubmed	Plasticity and expanding complexity of the hepatic transcription factor network during liver development.	CEBPA FOXA2	1.34e-04	11	55	2	16912278
Pubmed	Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure.	E2F1 FOXA2	1.34e-04	11	55	2	33103996
Pubmed	BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation.	SMARCC1 SMARCC2	1.34e-04	11	55	2	12917342
Pubmed	Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program.	SMARCC1 SMARCC2	1.34e-04	11	55	2	18003620
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS2 ADAMTS20 ADAMTS13	9.49e-06	19	40	3	50
GeneFamily	Fibronectin type III domain containing	LRFN3 FNDC4 EPHA10	5.29e-03	160	40	3	555
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	SMARCC1 SMARCC2	6.12e-03	53	40	2	532
GeneFamily	X-linked mental retardation\|Angiotensin receptors	IQSEC2 HCFC1	6.12e-03	53	40	2	103
Coexpression	PEREZ_TP53_TARGETS	JAG2 COL4A4 LAMB4 ARHGEF40 CEBPA HOXC13 ACSBG1 ADAMTS2 ADRM1 GLDC DIDO1 VWCE ARHGEF17 MYRF	9.70e-08	1201	54	14	M4391
Coexpression	RODRIGUES_NTN1_TARGETS_DN	MYOF CEBPA POU3F1 CACNA1I KLF2	2.04e-05	161	54	5	M11857
Coexpression	FOROUTAN_PRODRANK_TGFB_EMT_DN	CITED2 JAG2 GLDC FOXA2	2.50e-05	82	54	4	M42504
Coexpression	GSE30083_SP1_VS_SP4_THYMOCYTE_DN	ADAM19 ACSBG1 ADAMTS20 IGFLR1 KLF2	5.74e-05	200	54	5	M5030
Coexpression	GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_DN	CITED2 ADAM19 CEBPA IQSEC2 FAM89B	5.74e-05	200	54	5	M8575
Coexpression	FOROUTAN_TGFB_EMT_DN	CITED2 JAG2 GLDC FOXA2	7.36e-05	108	54	4	M42502
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	GOPC ACSBG1 E2F1 POU3F1 SYNGAP1	1.25e-06	152	55	5	669d8f12fdb110ed72f4e5348b7b5350144a061c
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GAS2L1 VPS13D E2F1 ARHGEF17	5.14e-05	165	55	4	94a5211072464fc24592bb107a853ce832e816fe
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	JAG2 LAMB4 POU3F1 ADARB2	5.77e-05	170	55	4	0cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	JAG2 LAMB4 POU3F1 ADARB2	5.77e-05	170	55	4	2d880223d01bde4bf777bd6f50b7d2768489075f
ToppCell	P07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KCNH6 ACSBG1 ADAMTS20 POU3F1	6.04e-05	172	55	4	8d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCell	Nasal_Brush-Epithelial-Basal_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	XIRP1 FNDC4 POU3F1 SPOCD1	6.60e-05	176	55	4	fc5787946f5a10056d326d070620575ae4081836
ToppCell	Nasal_Brush-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	XIRP1 FNDC4 POU3F1 SPOCD1	6.60e-05	176	55	4	5daaba0853afe7d20d4635169ccd4f96e735b938
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A4 ADAMTS2 ADAMTS20 ADARB2	7.36e-05	181	55	4	9842537f9a607d8557c43790008d175edab1f32c
ToppCell	Control-Epithelial_alveolar-AT_1-AT1-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL4A4 FOXA2 MYRF ANKRD33B	7.52e-05	182	55	4	a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOF CEBPA E2F1 IGFLR1	7.52e-05	182	55	4	3dec003bad0f3716cf8163861a9d4302a7d6df8c
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSBG1 ADAMTS20 POU3F1 ADARB2	7.68e-05	183	55	4	2cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSBG1 ADAMTS20 POU3F1 ADARB2	7.68e-05	183	55	4	98fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSBG1 ADAMTS20 POU3F1 ADARB2	7.85e-05	184	55	4	da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL4A4 MYOF FOXA2 MYRF	8.18e-05	186	55	4	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	droplet-Marrow-nan-24m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA G6PC3 GART WDR43	8.35e-05	187	55	4	f491ec986dd44e2dabdf4a75c3101e3b6c921872
ToppCell	droplet-Marrow-nan-24m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA G6PC3 GART WDR43	8.35e-05	187	55	4	96dc5dc4dbc1b33c2e66666e9027cfbf7972090b
ToppCell	droplet-Marrow-nan-21m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA G6PC3 GART WDR43	8.52e-05	188	55	4	f94dc08948a823f47882aa0714b9a60de4ff85d5
ToppCell	AT1-AT2_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	COL4A4 FOXA2 MYRF ANKRD33B	8.52e-05	188	55	4	be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCell	droplet-Marrow-nan-21m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA G6PC3 GART WDR43	8.52e-05	188	55	4	7c67330c36696a7772364af67c6df4e6406fa742
ToppCell	droplet-Marrow-BM-1m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA G6PC3 GART WDR43	8.70e-05	189	55	4	b81540e097e95158851e07bfd78640ed6e64c2cf
ToppCell	droplet-Marrow-BM-1m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA G6PC3 GART WDR43	8.70e-05	189	55	4	0fda1a3f1e87fadf5309c8267beaa4501983b1dd
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|Epithelial / Disease state, Lineage and Cell class	COL4A4 FNDC4 SPOCD1 MYRF	8.70e-05	189	55	4	4178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A4 ADAMTS2 ADAMTS20 ADARB2	8.70e-05	189	55	4	979b7fa947538aa7ca4a219263da2575869a2caa
ToppCell	MatrixFB-Fibroblast-C\|MatrixFB / shred on cell class and cell subclass (v4)	COL4A4 ADAMTS2 MYRF KLF2	8.88e-05	190	55	4	d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCell	MS-Treg-exh_CD4\|MS / Condition, Cell_class and T cell subcluster	GART FAM89B PANO1 SYNGAP1	9.25e-05	192	55	4	c6722bf142c84ccedd99c1a3344085aecb4cbab4
ToppCell	facs-Marrow-KLS-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPA GART SMARCC1 WDR43	9.62e-05	194	55	4	c9ebdcc2ea600975dade68a41fa65d1f8a5a5926
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A4 ADAMTS2 ADAMTS20 ADARB2	9.82e-05	195	55	4	98ca9f3aa36211dde1e6f7f3817b9418c95e583e
ToppCell	proximal-3-Hematologic-Plasma\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GLDC ANKRD33B EPHA10 KLF2	1.00e-04	196	55	4	1ca453582b5db8f1ea20a846e698c54edf0a1f25
ToppCell	proximal-Hematologic-Plasma-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GLDC ANKRD33B EPHA10 KLF2	1.00e-04	196	55	4	f6e842b18765c2d923706cabb5d17efeff1da5aa
ToppCell	proximal-Hematologic-Plasma\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GLDC ANKRD33B EPHA10 KLF2	1.00e-04	196	55	4	621f112a71f3d82fd75da8addfb16d86f590fe33
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	JAG2 E2F1 FOXA2 MYRF	1.02e-04	197	55	4	49689a03ab31e53386dbe15c77c09ca3a14ebf4e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	JAG2 MYOF POU3F1 WDR43	1.04e-04	198	55	4	fc00cb25cdc6c31b7f9d397bc9f9a8f4e9708003
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL4A4 MYOF FOXA2 MYRF	1.06e-04	199	55	4	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYOF XIRP1 CEBPA KLF2	1.06e-04	199	55	4	e7faf7d0cb43cf93149c446e5f718f84fa85477c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYOF XIRP1 CEBPA KLF2	1.06e-04	199	55	4	e245851a5bddf56f7e13a7fb7c5fda2fd275dae3
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2--L1-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL4A4 ADAMTS2 ADAMTS20 ADARB2	1.08e-04	200	55	4	f268cb1bb047e88913a828614b0a77871f5f8814
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL4A4 ADAMTS2 ADAMTS20 ADARB2	1.08e-04	200	55	4	5ff9ac97ef970b3b74ebb07f62a0a1f4176a10b4
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LRFN3 ARHGEF17 PHC1 WDR43	1.08e-04	200	55	4	36de49593cf6ff1c9229fcceb150c1d68658a360
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL4A4 MYOF FOXA2 MYRF	1.08e-04	200	55	4	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL4A4 ADAMTS2 ADAMTS20 ADARB2	1.08e-04	200	55	4	7345cc7dc24b9174541a3e68ecac8c4c092be400
Drug	Naringenine [480-41-1]; Down 200; 14.6uM; PC3; HT_HG-U133A	GAS2L1 MYOF VPS13D ARHGEF40 E2F1 ARHGEF17 KLF2	3.82e-07	195	54	7	4597_DN
Drug	Ondansetron Hydrochloride [103639-04-9]; Down 200; 12.2uM; PC3; HT_HG-U133A	CITED2 GAS2L1 MYOF VPS13D LRFN3 ARHGEF17 KLF2	4.10e-07	197	54	7	5796_DN
Drug	0297417-0002B [362658-29-5]; Down 200; 10uM; PC3; HT_HG-U133A	VPS13D ARHGEF40 SMARCC2 E2F1 IGFLR1 FOXA2	6.51e-06	194	54	6	6895_DN
Drug	Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; PC3; HT_HG-U133A	KCNH6 LAMB4 ACSBG1 POLR2A CACNA1I ARHGEF17	6.90e-06	196	54	6	4281_UP
Drug	Clindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; PC3; HT_HG-U133A	MYOF DCAF10 LRFN3 SMARCC2 E2F1 FOXA2	7.11e-06	197	54	6	5815_DN
Drug	Nifenazone [2139-47-1]; Down 200; 13uM; HL60; HG-U133A	MYOF VPS13D POLR2A IGFLR1 HCFC1 KLF2	7.53e-06	199	54	6	1439_DN
Drug	Vitamin K 3	CITED2 ADAM19 CEBPA GOPC GLDC LRFN3 GART FAM89B SMARCC2 E2F1 TSC22D2 MYRF	2.83e-05	1249	54	12	ctd:D024483
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	MYOF CEBPA POLR2A SMARCC2 ARHGEF17	7.68e-05	185	54	5	5585_DN
Drug	Lithocholic acid [434-13-9]; Up 200; 10.6uM; HL60; HT_HG-U133A	GAS2L1 MYOF ACSBG1 MYRF HCFC1	8.08e-05	187	54	5	2571_UP
Drug	17-AAG; Down 200; 1uM; PC3; HT_HG-U133A	JAG2 G6PC3 E2F1 TSC22D2 FOXA2	8.29e-05	188	54	5	1218_DN
Drug	0297417-0002B [362658-29-5]; Down 200; 10uM; MCF7; HT_HG-U133A	JAG2 CEBPA SMARCC2 E2F1 HCFC1	8.93e-05	191	54	5	6900_DN
Drug	15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A	VPS13D HOXC13 LRFN3 DIDO1 TSC22D2	9.16e-05	192	54	5	6990_DN
Drug	Nilutamide [63612-50-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A	LAMB4 POLR2A SMARCC2 ARHGEF17 HCFC1	9.61e-05	194	54	5	5362_UP
Drug	Pindolol [13523-86-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A	JAG2 MYOF VPS13D G6PC3 KLF2	9.85e-05	195	54	5	6834_DN
Drug	Lobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A	MYOF VPS13D ACSBG1 CACNA1I ADAMTS13	9.85e-05	195	54	5	2897_UP
Drug	Cholecalciferol [67-97-0]; Up 200; 10.4uM; MCF7; HT_HG-U133A	LAMB4 VPS13D ARHGEF40 CACNA1I ADAMTS13	9.85e-05	195	54	5	3298_UP
Drug	Dipyridamole [58-32-2]; Down 200; 8uM; HL60; HG-U133A	MYOF VPS13D POLR2A GART DIDO1	9.85e-05	195	54	5	2017_DN
Drug	Pirenzepine dihydrochloride [29868-97-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A	VPS13D CEBPA LRFN3 E2F1 HCFC1	1.01e-04	196	54	5	7226_DN
Drug	Naltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; PC3; HT_HG-U133A	LRFN3 IQSEC2 CACNA1I FOXA2 MYRF	1.01e-04	196	54	5	2047_UP
Drug	Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	VPS13D GART SMARCC2 DIDO1 HCFC1	1.01e-04	196	54	5	3416_DN
Drug	Methoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; MCF7; HT_HG-U133A	JAG2 MYOF G6PC3 LRFN3 HCFC1	1.01e-04	196	54	5	5007_DN
Drug	Folic acid [59-30-3]; Up 200; 9uM; MCF7; HT_HG-U133A	JAG2 IQSEC2 SMARCC2 CACNA1I ARHGEF17	1.01e-04	196	54	5	2783_UP
Drug	Mefenamic acid [61-68-7]; Down 200; 16.6uM; PC3; HT_HG-U133A	HOXC13 GART SMARCC2 DIDO1 FOXA2	1.01e-04	196	54	5	1821_DN
Drug	Nefopam hydrochloride [23327-57-3]; Up 200; 13.8uM; HL60; HT_HG-U133A	MYOF VPS13D ARHGEF40 E2F1 HCFC1	1.01e-04	196	54	5	2355_UP
Drug	Isometheptene mucate; Down 200; 8.2uM; HL60; HT_HG-U133A	GAS2L1 LAMB4 IQSEC2 E2F1 TSC22D2	1.03e-04	197	54	5	3145_DN
Drug	Tetracaone hydrochloride [136-47-0]; Up 200; 13.2uM; MCF7; HT_HG-U133A	MYOF LRFN3 IQSEC2 TSC22D2 MYRF	1.03e-04	197	54	5	2888_UP
Drug	Pyrithyldione [77-04-3]; Up 200; 24uM; MCF7; HT_HG-U133A	VPS13D POLR2A IQSEC2 CACNA1I HCFC1	1.03e-04	197	54	5	6801_UP
Drug	CP-320650-01 [172079-28-6]; Down 200; 10uM; PC3; HT_HG-U133A	GAS2L1 VPS13D IQSEC2 HCFC1 KLF2	1.03e-04	197	54	5	4557_DN
Drug	Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	MYOF VPS13D SMARCC2 ADAMTS13 HCFC1	1.03e-04	197	54	5	2821_UP
Drug	Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; MCF7; HT_HG-U133A	ARHGEF40 SMARCC2 ARHGEF17 MYRF HCFC1	1.03e-04	197	54	5	3209_UP
Drug	ICI 182,780; Down 200; 0.01uM; HL60; HT_HG-U133A	GAS2L1 MYOF ARHGEF40 E2F1 HCFC1	1.06e-04	198	54	5	6197_DN
Drug	Levamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; PC3; HT_HG-U133A	ACSBG1 FNDC4 POU3F1 FOXA2 HCFC1	1.06e-04	198	54	5	2094_UP
Drug	Bromopride [4093-35-0]; Up 200; 11.6uM; PC3; HT_HG-U133A	CEBPA ACSBG1 POLR2A ARHGEF17 HCFC1	1.06e-04	198	54	5	4278_UP
Drug	Iocetamic acid [16034-77-8]; Down 200; 6.6uM; HL60; HT_HG-U133A	KCNH6 GAS2L1 ACSBG1 TSC22D2 HCFC1	1.06e-04	198	54	5	3022_DN
Drug	Phenelzine sulfate [156-51-4]; Up 200; 17uM; PC3; HT_HG-U133A	COL4A4 ACSBG1 FNDC4 CACNA1I MYRF	1.06e-04	198	54	5	3802_UP
Drug	Dicumarol [66-76-2]; Up 200; 11.8uM; PC3; HT_HG-U133A	JAG2 MYOF CEBPA IQSEC2 ARHGEF17	1.06e-04	198	54	5	4323_UP
Drug	Disopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A	ADAM19 SMARCC2 E2F1 ARHGEF17 HCFC1	1.06e-04	198	54	5	7035_UP
Drug	Canrenoic acid potassium salt [2181-04-6]; Down 200; 10uM; PC3; HT_HG-U133A	CITED2 JAG2 MYOF DIDO1 HCFC1	1.06e-04	198	54	5	7135_DN
Drug	rosiglitazone; Down 200; 10uM; HL60; HT_HG-U133A	MYOF LAMB4 IQSEC2 E2F1 HCFC1	1.08e-04	199	54	5	2693_DN
Drug	Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; MCF7; HT_HG-U133A	MYOF G6PC3 GART TSC22D2 HCFC1	1.08e-04	199	54	5	4831_DN
Drug	Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A	VPS13D CEBPA E2F1 TSC22D2 ARHGEF17	1.08e-04	199	54	5	5458_DN
Drug	estradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A	VPS13D E2F1 TSC22D2 HCFC1 KLF2	1.08e-04	199	54	5	7000_DN
Drug	alpha-Santonin [481-06-1]; Down 200; 16.2uM; PC3; HT_HG-U133A	GAS2L1 HOXC13 DCAF10 IQSEC2 HCFC1	1.08e-04	199	54	5	4531_DN
Drug	wortmannin from Penicillium funiculosum; Down 200; 0.01uM; MCF7; HT_HG-U133A	JAG2 VPS13D CEBPA LRFN3 KLF2	1.11e-04	200	54	5	7002_DN
Disease	opportunistic bacterial infectious disease (implicated_via_orthology)	SMARCC1 SMARCC2	1.13e-04	9	53	2	DOID:0050340 (implicated_via_orthology)
Disease	Coffin-Siris syndrome (implicated_via_orthology)	SMARCC1 SMARCC2	1.13e-04	9	53	2	DOID:1925 (implicated_via_orthology)
Disease	tetralogy of Fallot (implicated_via_orthology)	CITED2 PHC1	2.84e-04	14	53	2	DOID:6419 (implicated_via_orthology)
Disease	macula measurement	COL4A4 E2F1 TSC22D2 SYNGAP1	3.74e-04	189	53	4	EFO_0008375
Disease	age of onset of asthma	ADAM19 CEBPA MYRF	3.93e-04	79	53	3	OBA_2001001
Disease	Mental Retardation, X-Linked 1	IQSEC2 HCFC1	1.52e-03	32	53	2	C2931498
Disease	eosinophil percentage of leukocytes	ADAM19 CEBPA ANKRD33B EPHA10 PHC1 KLF2	2.14e-03	746	53	6	EFO_0007991
Disease	Moyamoya disease	TSC22D2 MYRF	2.36e-03	40	53	2	MONDO_0016820
Disease	pulmonary function measurement, smoking behaviour measurement, FEV/FEC ratio	ADAM19 ARHGEF17	3.25e-03	47	53	2	EFO_0003892, EFO_0004713, EFO_0005671
Disease	sexual dimorphism measurement	ARHGEF40 G6PC3 POLR2A E2F1 ADAMTS13 SPOCD1 MYRF	3.49e-03	1106	53	7	EFO_0021796

Protein segments in the cluster

Peptide	Gene	Start	Entry
GPGLLCMAGHTGPEG	ARHGEF40	476	Q8TER5
CNTPGHGGSIDSGPM	ADAM19	681	Q9H013
SGPPGCPGDHGMPGL	COL4A4	1126	P53420
CPGDHGMPGLRGQPG	COL4A4	1131	P53420
GAPGSGCGPSGHVMA	ADAMTS13	236	Q76LX8
VPPADGTDCGPGMHC	ADAMTS20	526	P59510
GPPLDGTMCAPGKHC	ADAMTS2	531	O95450
GTGPEGGGARCMTPP	ANKRD33B	6	A6NCL7
CQAHLAMGGGPGPGT	ADARB2	196	Q9NS39
MSAGGPCPAAAGGGP	GOPC	1	Q9HD26
SFGPGGPCGTSPMDG	ARHGEF17	1696	Q96PE2
MATGAPCSAGPLLGP	HCFC1	1181	P51610
SEGLGMGAGPACPLP	MBD6	496	Q96DN6
GKTMPPGSHSPSGAG	PSMG3-AS1	216	Q96PY0
IDGCGSDAGPGMPGT	JAG2	586	Q9Y219
GMPGTAASGVCGPHG	JAG2	596	Q9Y219
PSSSHMGGPPAGVGL	IQSEC2	276	Q5JU85
TGPGSPSGHCMITGA	G6PC3	106	Q9BUM1
SQNSMGAGPCAPGHP	KCNH6	766	Q9H252
MNGLPSAEAPGGAGC	FAM89B	1	Q8N5H3
MFPFGPHSPGGDGSA	DCAF10	1	Q5QP82
HLGPAMSPSPGASGG	POU3F1	136	Q03052
PCGAPHAPFLGGTMI	LRFN3	526	Q9BTN0
GEPGSPPRMHCGADG	EPHA10	246	Q5JZY3
GSGPGHPPSGTRMCG	PANO1	111	I0J062
MALAGAPAGGPCAPA	E2F1	1	Q01094
APAGPGGAVMPGGAH	CEBPA	111	P49715
SSDEGSPCPGMGGPL	GAS2L1	601	Q99501
MGGPLDAPGSPLACT	GAS2L1	611	Q99501
MPSGCHSSPPSGLRG	FNDC4	1	Q9H6D8
GPAPGHEDCNGRMPS	CACNA1I	1086	Q9P0X4
LLDPEPGPGGGMAHG	IGFLR1	266	Q9H665
PGPHALGMSGLHGPN	DIDO1	1756	Q9BTC0
GAGYGCPHGDPSMLD	ACSBG1	6	Q96GR2
PGKAPSMDGLGSSCP	HOXC13	51	P31276
ASGVSPMECPPGGGA	LAMB4	1026	A4D0S4
GMGPHLSPSLSPLGG	FOXA2	101	Q9Y261
MGGSGPLSAVPGGPH	TSC22D2	486	O75157
GPGLAPLGAAGHPGM	SMARCC1	976	Q92922
MPGAVPGSGHPGVAG	SMARCC2	1061	Q8TAQ2
PPMPGALGASGSSGH	ADRM1	131	Q16186
RMSCGGGRPFCPPGH	ATAD3B	631	Q5T9A4
HAMGPGTVNGGHPPS	CITED2	71	Q99967
AMATPSPAGGCGGGL	TNRC18	1186	O15417
LFHMAADGPGPPGGH	SYNGAP1	931	Q96PV0
GASSMPGLSPDGPGA	SPOCD1	31	Q6ZMY3
MHGGGPPSGDSACPL	POLR2A	1	P24928
SGCCPGWAPSMGGGH	VWCE	51	Q96DN2
LGQLPSSGMGGGSCP	PHC1	291	P78364
GGPNTGGMGAYCPAP	GART	226	P22102
CSPGGMLSSAGGAPE	ZNF503	236	Q96F45
GMGHLRASGATPCPP	XIRP1	981	Q702N8
MAAGGGGSCDPLAPA	WDR43	1	Q15061
ACPGAPEPGGGSGML	VPS13D	416	Q5THJ4
FCIPHGGGGPGMGPI	GLDC	756	P23378
GAPGPAASCMRGPGG	KLF2	151	Q9Y5W3
HPNDLSGPSVPGMGG	MYOF	131	Q9NZM1
MPGSSGVHHLSPPGG	MYRF	66	Q9Y2G1