Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

BRIP1 ATAD5 ZGRF1 MSH5 RFC1 ERCC6L2 HFM1

2.40e-051271347GO:0008094
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-6 BRIP1 ZCWPW2 ATAD5 ZGRF1 LARS1 ZNFX1 MSH5 RFC1 DDX10 ERVK-8 ERCC6L2 HFM1 PARN TRMT1L

2.90e-0564513415GO:0140640
GeneOntologyMolecularFunctionDNA clamp unloader activity

ATAD5 RFC1

4.47e-0521342GO:0061860
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 BRIP1 ATAD5 ZGRF1 MSH5 RFC1 ERVK-8 ERCC6L2 HFM1

7.04e-052621349GO:0140097
GeneOntologyMolecularFunctionhelicase activity

BRIP1 ZCWPW2 ZGRF1 ZNFX1 DDX10 ERCC6L2 HFM1

9.63e-051581347GO:0004386
GeneOntologyMolecularFunctioncell adhesion molecule binding

FLNA ANK3 CAPG POSTN NEO1 FBN1 CDH20 NRXN1 TENM3 DMD PALLD CDH8 PHLDB2

2.00e-0459913413GO:0050839
GeneOntologyMolecularFunctionATP-dependent activity

BRIP1 ZCWPW2 ATAD5 ZGRF1 ZNFX1 MSH5 RFC1 ABCB1 DDX10 ERCC6L2 HFM1 ATP2B3 SLC27A4

2.55e-0461413413GO:0140657
GeneOntologyBiologicalProcessDNA damage response

ERVK-6 SHLD2 TICRR BRIP1 MAPT ATAD5 ZGRF1 MSH5 RFC1 NDUFS6 TAF9B ERVK-8 ERCC6L2 SMARCB1 BOD1L1 ATM SPRTN FH NEK11

1.02e-0595913119GO:0006974
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-6 RFC1 ERVK-8 PINX1 PARN ATM

1.48e-05831316GO:0006278
GeneOntologyBiologicalProcesschromosome organization

SHLD2 FLNA BRIP1 CENPC MAPT ZGRF1 MSH5 RFC1 AKAP8L RESF1 SMARCB1 PINX1 HFM1 PARN ATM

3.10e-0568613115GO:0051276
GeneOntologyBiologicalProcessDNA clamp unloading

ATAD5 RFC1

4.00e-0521312GO:0090618
GeneOntologyBiologicalProcessDNA repair

ERVK-6 SHLD2 TICRR BRIP1 ZGRF1 MSH5 RFC1 ERVK-8 ERCC6L2 SMARCB1 BOD1L1 ATM SPRTN FH

6.59e-0564813114GO:0006281
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-8 SMARCB1

6.84e-05131313GO:0015074
GeneOntologyBiologicalProcesscardiac muscle thin filament assembly

NRAP NEB

1.20e-0431312GO:0071691
GeneOntologyCellularComponentaxonal growth cone

FLNA MAPT NEO1 NRXN1 PALLD

1.04e-05451355GO:0044295
GeneOntologyCellularComponentZ disc

FLNA NRAP ANK3 NEB XIRP2 DMD PALLD

5.71e-051511357GO:0030018
GeneOntologyCellularComponentI band

FLNA NRAP ANK3 NEB XIRP2 DMD PALLD

1.04e-041661357GO:0031674
GeneOntologyCellularComponentElg1 RFC-like complex

ATAD5 RFC1

1.24e-0431352GO:0031391
GeneOntologyCellularComponentmyofibril

FLNA NRAP ANK3 NEB XIRP2 DMD PALLD ALPP

4.05e-042731358GO:0030016
GeneOntologyCellularComponentanchoring junction

FLNA NRAP ANK3 ASH1L ABCB1 NEDD9 DOCK5 FAT2 CDH20 NRXN1 XIRP2 ANO7 DMD PALLD CDH8 PHLDB2

5.68e-0497613516GO:0070161
GeneOntologyCellularComponentcontractile muscle fiber

FLNA NRAP ANK3 NEB XIRP2 DMD PALLD ALPP

6.03e-042901358GO:0043292
GeneOntologyCellularComponentexternal side of apical plasma membrane

ABCB1 SLC38A1

6.11e-0461352GO:0098591
GeneOntologyCellularComponentneuromuscular junction

ANK3 PCLO POSTN NRXN1 LRP4

8.05e-041121355GO:0031594
GeneOntologyCellularComponentsarcomere

FLNA NRAP ANK3 NEB XIRP2 DMD PALLD

1.19e-032491357GO:0030017
MousePhenoincreased Harderian gland tumor incidence

BRIP1 ATAD5 PINX1

8.34e-0661063MP:0012437
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

NEPRO NRAS ATAD5 ACAD9 MKRN1 ZMYM2 GON4L SRP72 SRBD1 SPECC1 AKAP8L MYEF2 DDX10 TOMM70 PIGT PTPN13 UBP1 CTR9 GNL2 ANKRD11 PARN TRMT1L FHIP1A EDRF1

3.95e-0914971362431527615
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

FLNA BRIP1 CENPC ATAD5 ZMYM2 SRP72 ZDBF2 RFC1 NDUFS6 DDX10 EFTUD2 TAF3 TAF9B GNL2 ANKRD11 PINX1 PARN BOD1L1 PLRG1

6.57e-099541361936373674
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

FLG FLNA CENPC ZNF658 PCLO BIVM ASH1L SRP72 SRBD1 NEB AKAP8L ABCB1 ZBED4 NRXN1 CTR9 BOD1L1 ATM DMD ATP2B3 SLC27A4 ZNF292 VAT1

4.59e-0814421362235575683
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

ANK3 ACAD9 NEB AKAP8L XIRP2 ERCC6L2 GNL2 ANKRD11 SMARCB1 ATM PLRG1 HYDIN ZNF292

8.69e-084971361336774506
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ATAD5 ZMYM2 ZNFX1 ZDBF2 RFC1 NEB MYEF2 SLC38A1 PIGT UBP1 SMARCB1 HFM1 WDFY3 ATP2B3

2.31e-076381361431182584
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

FLNA NEPRO NRAS CENPC ZMYM2 RFC1 SRBD1 AKAP8L DDX10 EFTUD2 CTR9 GNL2 PINX1 PARN BOD1L1 PLRG1 SLC27A4

3.52e-079891361736424410
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FLNA ZGRF1 GON4L LINGO2 RFC1 NEB EFTUD2 FAT2 DMD

3.86e-07234136936243803
Pubmed

Functional proteomics mapping of a human signaling pathway.

FLNA ANK3 VPS8 ASH1L ZMYM2 SRP72 ZZEF1 NEDD9 MAST4 TENM3 CTR9 PLCL2 SPRTN

6.21e-075911361315231748
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DOCK3 ANK3 CEP290 ASH1L HECTD4 LARS1 ZMYM2 ZNFX1 BTBD1 SPECC1 AKAP8L PTPN13 FBN1 CTR9 LRP4 ATM WDFY3 TBC1D23 ZNF292

6.70e-0712851361935914814
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

FLNA NRAS ANK3 PCLO ASH1L LARS1 SAXO1 ZZEF1 MYEF2 EFTUD2 TOMM70 ZNF561 FH HYDIN VAT1

6.86e-078071361530575818
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

FLNA TRAF1 ACAD9 PCLO LARS1 SRP72 RFC1 DDX10 EFTUD2 SLC38A1 TOMM70 CTR9 GNL2 BOD1L1 ATM FH ATP2B3 PLRG1 SLC27A4 VAT1

7.45e-0714251362030948266
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

BRIP1 CENPC ATAD5 ZMYM2 RFC1 SRBD1 DDX10 TAF3 GNL2 SMARCB1 PINX1 BOD1L1 ZNF292

8.53e-076081361336089195
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

SHLD2 FLNA TICRR ANK3 ACAD9 CAPG ASH1L ZNF429 MSH5 PTPN13 RESF1 PTPRR UBP1 CTR9 PLCL2 BOD1L1 ZMAT1

1.24e-0610841361711544199
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

C12orf56 GON4L SRP72 ZNFX1 ZZEF1 AKAP8L DOCK5 TOMM70 CTR9 PARN PLRG1 PALLD SLC27A4

1.78e-066501361338777146
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

CASP8AP2 ASH1L LARS1 ZNFX1 MYEF2 BOD1L1 CFAP97

2.52e-06153136710718198
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

CASP8AP2 TICRR ATAD5 CEP290 ZMYM2 RFC1 SRBD1 NDUFS6 EFTUD2 DOCK5 TAF9B ZBED4 UBP1 CTR9 ANKRD11 SMARCB1 PLRG1 SLC27A4

3.19e-0612941361830804502
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ANK3 CENPC ATAD5 CEP290 AKAP8L SLC38A1 POSTN TOMM70 PTPN13 PTPRR CTR9 PLCL2 GNL2 PINX1 DMD VAT1

3.71e-0610491361627880917
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

NRAP MKRN1 GON4L SRP72 BTBD1 NEB NEDD9 TOMM70 NEO1 XIRP2 PALLD

4.45e-064971361123414517
Pubmed

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.

NRAS ANK3 RFC1 AKAP8L DDX10 TOMM70 SMARCB1 FH PLRG1 PHLDB2

4.54e-064031361035253629
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

FLG HECTD4 ZMYM2 SRP72 AKAP8L MYEF2 EFTUD2 TAF3 PTPN13 ZBED4 NRXN1 GNL2 SMARCB1 ATM PLRG1 ZNF292

5.48e-0610821361638697112
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

FLNA NEPRO LARS1 SRP72 RFC1 SRBD1 EFTUD2 GNL2 SMARCB1 TRMT1L PLRG1 PALLD

5.82e-066151361231048545
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ANK3 RASA3 SPECC1 AKAP8L SLC38A1 PTPN13 TENM3 DMD PHLDB2 VAT1

6.66e-064211361036976175
Pubmed

Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function.

CEP290 ABCB1 PTPRR ALPP

7.39e-0632136412493773
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

FBN1 RESF1 NRXN1 DMD ZNF292

8.99e-0671136533541421
Pubmed

Competition is a driving force in topographic mapping.

EPHA6 TENM3 CDH8

9.43e-0611136322065784
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

TICRR NEPRO ATAD5 LARS1 SRP72 RFC1 SRBD1 AKAP8L DDX10 GNL2 PINX1 TRMT1L PLRG1

9.50e-067591361335915203
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

ZNFX1 RESF1 NRXN1 CTR9 PLCL2 LRP4

1.28e-05130136612421765
Pubmed

Serum Antibodies to N-Glycolylneuraminic Acid Are Elevated in Duchenne Muscular Dystrophy and Correlate with Increased Disease Pathology in Cmah-/-mdx Mice.

DMD CMAHP

1.52e-052136234294193
Pubmed

A human-specific deletion in mouse Cmah increases disease severity in the mdx model of Duchenne muscular dystrophy.

DMD CMAHP

1.52e-052136220668298
Pubmed

Filaggrin and Periostin Expression Is Altered in Eosinophilic Esophagitis and Normalized With Treatment.

FLG POSTN

1.52e-052136228644349
Pubmed

Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy.

DMD CMAHP

1.52e-052136229912990
Pubmed

Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states.

FBN1 DMD

1.52e-052136217237794
Pubmed

DOCK3 regulates normal skeletal muscle regeneration and glucose metabolism.

DOCK3 DMD

1.52e-052136237742307
Pubmed

Transcriptional signatures of synaptic vesicle genes define myotonic dystrophy type I neurodegeneration.

MAPT DMD

1.52e-052136233955002
Pubmed

DOCK3 is a dosage-sensitive regulator of skeletal muscle and Duchenne muscular dystrophy-associated pathologies.

DOCK3 DMD

1.52e-052136232766788
Pubmed

Duchenne-like myopathy in double-mutant mdx mice expressing exaggerated mast cell activity.

FBN1 DMD

1.52e-05213627561939
Pubmed

Histone methyltransferase Ash1L mediates activity-dependent repression of neurexin-1α.

ASH1L NRXN1

1.52e-052136227229316
Pubmed

hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ.

BRIP1 MSH5

1.52e-052136226055704
Pubmed

Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.

DMD CMAHP

1.52e-052136230281092
Pubmed

Increasing LRP4 diminishes neuromuscular deficits in a mouse model of Duchenne muscular dystrophy.

LRP4 DMD

1.52e-052136233987657
Pubmed

Direct and Indirect Effects of Filamin A on Tau Pathology in Neuronal Cells.

FLNA MAPT

1.52e-052136236399251
Pubmed

Mutational analysis of FLASH and PTPN13 genes in colorectal carcinomas.

CASP8AP2 PTPN13

1.52e-052136218038312
Pubmed

Periostin Is Required for the Maintenance of Muscle Fibers during Muscle Regeneration.

POSTN DMD

1.52e-052136233807264
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

FLNA SRP72 RFC1 AKAP8L MYEF2 DDX10 GNL2 PINX1 PARN TRMT1L

2.17e-054831361036912080
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PCLO NRXN1 CTR9 WDFY3 ZNF292

2.43e-0587136512465718
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

ATAD5 LARS1 ZMYM2 GON4L SRP72 RFC1 SMARCB1 PARN PLRG1

2.65e-05394136927248496
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MAPT ATAD5 ASH1L ZZEF1 AKAP8L MYEF2 TAF3 RESF1 TAF9B GNL2 SMARCB1 LRP4 WDFY3 PHLDB2 ARAP2

3.32e-0511161361531753913
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

GALNTL6 CFAP47 TICRR PCLO CEP290 ZZEF1 DOCK5 CDH20 ZBED4 FBXO43 BOD1L1 ATM

3.43e-057361361229676528
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MAPT RASSF2 SPECC1 PTPN13 RESF1 MAST4 ANKRD11 BOD1L1 PALLD EDRF1 CFAP97 PHLDB2 ARAP2

3.53e-058611361336931259
Pubmed

STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.

FLNA RFC1 SRBD1 DDX10 EFTUD2 GNL2 PINX1 TRMT1L

3.66e-05316136831665637
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

ACAD9 CEP290 SRP72 AKAP8L DDX10 TOMM70 PIGT PTPN13 FBN1 GNL2 PHLDB2 SLC27A4

4.33e-057541361233060197
Pubmed

Human transcription factor protein interaction networks.

FLG NEPRO ATAD5 LARS1 ZMYM2 GON4L SRP72 RFC1 AKAP8L DDX10 TAF3 FBN1 RESF1 TAF9B GNL2 SMARCB1 TRMT1L

4.49e-0514291361735140242
Pubmed

A comparison of the bone and growth phenotype of mdx, mdx:Cmah-/- and mdx:Utrn+/- murine models with the C57BL/10 wild-type mouse.

DMD CMAHP

4.54e-053136231754018
Pubmed

Possible involvement of mitogen- and stress-activated protein kinase 1, MSK1, in metaphase-II arrest through phosphorylation of EMI2 in mouse oocytes.

FAT2 FBXO43

4.54e-053136221924255
Pubmed

Rac activation and inactivation control plasticity of tumor cell movement.

DOCK3 NEDD9

4.54e-053136218984162
Pubmed

A conserved interaction that is essential for the biogenesis of histone locus bodies.

CASP8AP2 GON4L

4.54e-053136225339177
Pubmed

Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.

ANK3 MAPT

4.54e-053136227356871
Pubmed

The FANCJ helicase unfolds DNA-protein crosslinks to promote their repair.

BRIP1 SPRTN

4.54e-053136236608669
Pubmed

Implications of increased S100β and Tau5 proteins in dystrophic nerves of two mdx mouse models for Duchenne muscular dystrophy.

MAPT DMD

4.54e-053136232240725
Pubmed

Chromatin-Remodeling Complex SWI/SNF Controls Multidrug Resistance by Transcriptionally Regulating the Drug Efflux Pump ABCB1.

ABCB1 SMARCB1

4.54e-053136227503929
Pubmed

LL5beta directs the translocation of filamin A and SHIP2 to sites of phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3) accumulation, and PtdIns(3,4,5)P3 localization is mutually modified by co-recruited SHIP2.

FLNA PHLDB2

4.54e-053136220236936
Pubmed

Structural Analysis of the SANT/Myb Domain of FLASH and YARP Proteins and Their Complex with the C-Terminal Fragment of NPAT by NMR Spectroscopy and Computer Simulations.

CASP8AP2 GON4L

4.54e-053136232722282
Pubmed

Prognostic evaluation of CapG, gelsolin, P-gp, GSTP1, and Topo-II proteins in non-small cell lung cancer.

CAPG ABCB1

4.54e-053136222190510
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

CASP8AP2 CENPC ATAD5 CAPG RFC1 TAF3 PHPT1 CTR9 SMARCB1 PARN BOD1L1 ATM TRMT1L PLRG1

4.62e-0510141361432416067
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

FLNA ACAD9 VPS8 LARS1 SRP72 RFC1 SPECC1 AKAP8L EFTUD2 TOMM70 PIGT GNL2 LRP4 ATM TRMT1L SLC27A4 ALPP

4.94e-0514401361730833792
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

FLNA LARS1 ZMYM2 EFTUD2 CTR9 BOD1L1 TRMT1L PALLD

5.17e-05332136832786267
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

FLG ANK3 ACAD9 CEP290 LARS1 EFTUD2 DOCK5 POSTN PIGT PTPN13 NRXN1 CTR9 PLCL2 EDRF1 FYB2 PHLDB2

6.19e-0513211361627173435
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

ZMYM2 SRBD1 MYEF2 DDX10 GNL2 PARN TRMT1L PLRG1

6.24e-05341136832971831
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

ATAD5 ZMYM2 SRBD1 AKAP8L UBP1 CTR9

7.26e-05177136626206133
Pubmed

Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology.

DDX10 LRP4 HYDIN

7.39e-0521136326234751
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

SHLD2 BRIP1 ATAD5 AKAP8L SMARCB1 PARN BOD1L1 ATM TRMT1L

7.76e-05453136929656893
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNA CENPC RASA3 LARS1 RFC1 SRBD1 AKAP8L MYEF2 DDX10 EFTUD2 CTR9 WDFY3 PLRG1 PALLD PHLDB2 SLC27A4

8.19e-0513531361629467282
Pubmed

Surveillance of different recombination defects in mouse spermatocytes yields distinct responses despite elimination at an identical developmental stage.

MSH5 ATM

9.06e-054136216055729
Pubmed

A genome-wide survey of RAS transformation targets.

NRAS DDX10

9.06e-054136210655059
Pubmed

ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin.

ATAD5 RFC1

9.06e-054136223277426
Pubmed

Four and half lim protein 2 (FHL2) stimulates osteoblast differentiation.

FLNA PALLD

9.06e-054136216355270
Pubmed

Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.

NEB XIRP2

9.06e-054136223985323
Pubmed

Are the so-called low penetrance breast cancer genes, ATM, BRIP1, PALB2 and CHEK2, high risk for women with strong family histories?

BRIP1 ATM

9.06e-054136218557994
Pubmed

Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo.

FLNA NEB

9.06e-054136216902413
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

FLNA ZMYM2 RFC1 DDX10 EFTUD2 GNL2 TRMT1L

1.00e-04271136732433965
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

ZCWPW2 CEP290 RFC1 TAF3 SMARCB1 BOD1L1 TRMT1L PLRG1 HYDIN

1.01e-04469136927634302
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

ATAD5 SRP72 SPECC1 MYEF2 GNL2 ATM TRMT1L PLRG1

1.10e-04370136822922362
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

ZMYM2 SRP72 ZDBF2 MYEF2 CTR9 SMARCB1 BOD1L1

1.28e-04282136723667531
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

FLG ATAD5 SRP72 RFC1 AKAP8L DDX10 EFTUD2 CTR9 GNL2 SMARCB1

1.41e-046051361028977666
Pubmed

MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms.

DOCK3 DMD

1.51e-045136224789910
Pubmed

Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases.

ASH1L ZNF292

1.51e-045136228191889
Pubmed

An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.

ANK3 DMD

1.51e-045136219109891
Pubmed

An anthropoid-specific segmental duplication on human chromosome 1q22.

ASH1L GON4L

1.51e-045136216545939
Pubmed

Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants.

MSH5 ATM

1.51e-045136215640358
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

FLNA LARS1 SRP72 RFC1 AKAP8L DDX10 EFTUD2 TAF3 TAF9B CTR9 GNL2 SMARCB1 TRMT1L FH PLRG1

2.09e-0413181361530463901
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

VPS8 GON4L TOMM70 ZBED4 TENM3 PLCL2 BOD1L1 ARAP2

2.10e-04407136812693553
Pubmed

BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands.

TICRR BRIP1

2.25e-046136230295604
Pubmed

Human SNF5/INI1, a component of the human SWI/SNF chromatin remodeling complex, promotes nucleotide excision repair by influencing ATM recruitment and downstream H2AX phosphorylation.

SMARCB1 ATM

2.25e-046136219805520
Pubmed

Molecular characterization and gene content of breakpoint boundaries in patients with neurofibromatosis type 1 with 17q11.2 microdeletions.

ATAD5 LRRC37B

2.25e-046136211468690
Pubmed

Dysregulation of NRAP degradation by KLHL41 contributes to pathophysiology in nemaline myopathy.

NRAP NEB

2.25e-046136230986853
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CASP8AP2 ANK3 CENPC ATAD5 ACAD9 NDUFS6 DDX10 EFTUD2 NEO1 PTPN13 CTR9 GNL2 ANKRD11 ATM PLRG1 EDRF1

2.40e-0414871361633957083
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

FLNA BRIP1 MAPT ZMYM2 RFC1 AKAP8L EFTUD2 TAF3 CTR9 ATM PHLDB2

2.43e-047741361115302935
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CASP8AP2 FLNA ZGRF1 ZMYM2 ZDBF2 AKAP8L PTPN13 RESF1

2.51e-04418136834709266
Pubmed

Nucleolar proteome dynamics.

RFC1 DDX10 EFTUD2 GNL2 PARN ATM TRMT1L PLRG1

2.55e-04419136815635413
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

CENPC ATAD5 ASH1L RFC1 DDX10 TAF3 PTPN13 TAF9B SMARCB1

2.61e-04533136930554943
InteractionH3C1 interactions

BRIP1 ANK3 CENPC MAPT ATAD5 CEP290 ASH1L ZMYM2 SRP72 RFC1 SRBD1 NEB ZZEF1 DDX10 EFTUD2 TAF3 XIRP2 CTR9 GNL2 PINX1 PARN ATM PALLD ZNF292

4.11e-0990113224int:H3C1
InteractionNUP43 interactions

CASP8AP2 FLNA NEPRO BRIP1 CENPC ASH1L ZMYM2 GON4L ZDBF2 RFC1 TAF3 FBN1 RESF1 TAF9B GNL2 ANKRD11 PARN BOD1L1 TRMT1L ZNF292

4.55e-0962513220int:NUP43
InteractionFLNC interactions

FLG FLNA NRAP ANK3 MAPT LARS1 XIRP2 FBXO43 PLRG1 PHLDB2

3.33e-0623413210int:FLNC
InteractionPOLR1G interactions

NEPRO CENPC ATAD5 RFC1 DDX10 TAF3 TAF9B CTR9 GNL2 ANKRD11 PINX1 PARN TRMT1L ZNF292

4.08e-0648913214int:POLR1G
InteractionSNRNP40 interactions

CASP8AP2 FLNA NEPRO BRIP1 CENPC ATAD5 GON4L ZDBF2 RFC1 SRBD1 EFTUD2 TAF9B GNL2 PINX1 TRMT1L PLRG1

4.33e-0663713216int:SNRNP40
InteractionNIFK interactions

NEPRO CENPC ATAD5 SRP72 RFC1 DDX10 EFTUD2 TAF3 GNL2 ANKRD11 PINX1 PARN TRMT1L

5.25e-0643113213int:NIFK
InteractionZNF330 interactions

NEPRO CENPC ATAD5 RFC1 SRBD1 DDX10 TAF3 CTR9 GNL2 ANKRD11 PINX1 PARN ZNF292

7.59e-0644613213int:ZNF330
InteractionFBXO22 interactions

ANK3 ACAD9 NEB AKAP8L EFTUD2 XIRP2 ERCC6L2 GNL2 ANKRD11 SMARCB1 ATM PLRG1 HYDIN ZNF292

1.26e-0554013214int:FBXO22
InteractionSMC5 interactions

FLNA BRIP1 CENPC ATAD5 ZMYM2 SRP72 ZDBF2 RFC1 NDUFS6 DDX10 EFTUD2 TAF3 TAF9B GNL2 ANKRD11 PINX1 PARN BOD1L1 PLRG1

2.81e-05100013219int:SMC5
InteractionH3-3A interactions

BRIP1 CENPC MAPT ATAD5 ASH1L ZMYM2 RFC1 SRBD1 DDX10 TAF3 GNL2 SMARCB1 PINX1 BOD1L1 FH ZNF292

3.21e-0574913216int:H3-3A
InteractionH2BC9 interactions

CASP8AP2 PCLO CEP290 ASH1L NEB TOMM70 XIRP2 UBP1 WDFY3 SPRTN ATP2B3 PALLD

3.78e-0544613212int:H2BC9
InteractionRPL31 interactions

NEPRO CENPC MAPT ATAD5 MKRN1 SRP72 RFC1 DDX10 EFTUD2 TAF3 GNL2 ANKRD11 PINX1 PARN TRMT1L

4.00e-0568013215int:RPL31
InteractionRPS6 interactions

NEPRO CENPC MAPT PCLO LARS1 SRP72 RFC1 AKAP8L MYEF2 DDX10 EFTUD2 GVINP1 GNL2 PINX1 PARN TRMT1L SPRTN

5.78e-0587413217int:RPS6
InteractionMAGEA9 interactions

BRIP1 ATAD5 ASH1L ZDBF2 TAF3 TAF9B CTR9 TRMT1L

6.94e-052081328int:MAGEA9
InteractionTERF2IP interactions

BRIP1 CENPC ATAD5 ZMYM2 RFC1 DDX10 TAF9B ANKRD11 PINX1 PARN BOD1L1 WDFY3 ZNF292

6.98e-0555213213int:TERF2IP
InteractionMAGEB2 interactions

NEPRO ASH1L SRP72 RFC1 SRBD1 MYEF2 DDX10 GNL2 PARN TRMT1L

1.03e-0434913210int:MAGEB2
InteractionPARP1 interactions

NEPRO CENPC MAPT ATAD5 RFC1 SRBD1 DDX10 EFTUD2 TAF3 PTPN13 UBP1 CTR9 GNL2 SMARCB1 PINX1 PARN ATM TRMT1L SPRTN SLC27A4 ZNF292

1.28e-04131613221int:PARP1
InteractionAGR2 interactions

FLNA NRAP NRAS ANK3 PCLO ASH1L LARS1 SAXO1 ZZEF1 MYEF2 EFTUD2 TOMM70 ANKRD11 ZNF561 FH HYDIN VAT1

1.30e-0493413217int:AGR2
Cytoband11q22-q23

DDX10 ATM

1.30e-046136211q22-q23
Cytoband3q12.2

TOMM70 TBC1D23

3.09e-04913623q12.2
CoexpressionZHANG_BREAST_CANCER_PROGENITORS_UP

CASP8AP2 NRAS RFC1 EFTUD2 SLC38A1 TOMM70 NEO1 ERCC6L2 FH CFAP97 ARAP2

1.30e-0543413211M15150
CoexpressionZHANG_BREAST_CANCER_PROGENITORS_UP

CASP8AP2 NRAS RFC1 EFTUD2 SLC38A1 TOMM70 NEO1 ERCC6L2 FH CFAP97 ARAP2

1.74e-0544813211MM1044
CoexpressionHELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP

CRISPLD2 FLNA MAPT AAMDC PCLO MSH5 ABCB1 NEDD9 FBN1 NRXN1 ALPP

2.27e-0546113211M14127
CoexpressionCHEBOTAEV_GR_TARGETS_DN

CRISPLD2 RASA3 MYEF2 LRP4 PALLD PHLDB2

4.00e-051241326M7876
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

ANK3 MAPT RASSF2 AAMDC MKRN1 HECTD4 MSH5 SPECC1 NEO1 PIGT CDH20 TAF9B LRP4 TBC1D23 ZMAT1 PHLDB2 VAT1

4.00e-05110213217M2369
CoexpressionRODRIGUES_THYROID_CARCINOMA_DN

ANK3 ZMYM2 ERCC6L2 DMD PHLDB2

4.72e-05781325M9814
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

ANK3 MAPT RASSF2 AAMDC MKRN1 HECTD4 MSH5 SPECC1 NEO1 PIGT CDH20 TAF9B LRP4 TBC1D23 ZMAT1 PHLDB2 VAT1

5.12e-05112413217MM1070
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2A

CFAP47 SLC16A9 RASSF2 SPECC1 FAT2 CFAP126 NRXN1 ZMAT1 PALLD HYDIN NEK11 ARAP2

5.34e-0560013212M39055
CoexpressionCHEBOTAEV_GR_TARGETS_DN

CRISPLD2 RASA3 MYEF2 LRP4 PALLD PHLDB2

5.67e-051321326MM470
CoexpressionGSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP

MKRN1 VPS8 ZZEF1 PTPN13 MAST4 CMAHP ARAP2

7.15e-052001327M9889
CoexpressionGSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_DN

CRISPLD2 TRAF1 ATAD5 CEP290 SPECC1 ABCB1 ARAP2

7.15e-052001327M7177
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

CASP8AP2 NEPRO NRAS CENPC ATAD5 PCLO CEP290 ZDBF2 ZBED4 ANKRD11 LRP4 PINX1 ATM TRMT1L

5.42e-0653213114Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_500

DOCK3 CASP8AP2 ZGRF1 SRBD1 HFM1 ATM EDRF1

1.55e-051291317gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k4_500
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

CASP8AP2 TICRR TRAF1 CENPC ATAD5 CEP290 ZMYM2 RFC1 TAF3 RESF1 ZBED4 GVINP1 PTPRR CTR9 PLCL2 GNL2 BOD1L1 ATM CMAHP CFAP97 ZNF292

2.66e-05125213121facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

CASP8AP2 TICRR CENPC ATAD5 ZGRF1 CEP290 ZMYM2 ZDBF2 RFC1 DDX10 ZBED4 GNL2 PINX1 BOD1L1 ATM DMD FH CMAHP CFAP97 SLC27A4 ZNF292

2.82e-05125713121facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_NeuroEpith_central_2500_K4

DOCK3 CASP8AP2 TICRR CENPC RASSF2 ATAD5 MKRN1 BIVM CEP290 ZMYM2 ZDBF2 RFC1 MYEF2 SLC38A1 TAF9B ZBED4 NRXN1 PTPRR BOD1L1 ATM WDFY3 DMD

3.24e-05137013122facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

CASP8AP2 ATAD5 AAMDC PCLO CEP290 HECTD4 ZDBF2 NEB NEDD9 NRXN1 LRP4 DMD CDH8 SLC27A4

5.34e-0565413114Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

DOCK3 CASP8AP2 TICRR CENPC ATAD5 ZGRF1 CEP290 ZMYM2 ZDBF2 RFC1 DDX10 ZBED4 GNL2 PINX1 BOD1L1 ATM DMD FH CMAHP CFAP97 SLC27A4 ZNF292

8.27e-05145913122facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

CEP290 ASH1L SRP72 RFC1 NEB ABCB1 DDX10 RESF1 MAST4 TAF9B ANKRD11 WDFY3 ZMAT1 CFAP97 VAT1

9.28e-0577813115gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000

CRISPLD2 CASP8AP2 CENPC ATAD5 AAMDC PCLO CEP290 ZDBF2 MYEF2 SLC38A1 PTPN13 TAF9B ATM DMD SPRTN ZMAT1 ZNF292

1.21e-0498613117Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500

DOCK3 CASP8AP2 TICRR BRIP1 ZGRF1 SRBD1 DDX10 HFM1 ATM EDRF1

1.41e-0438513110gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

ATAD5 ZGRF1 CEP290 ZMYM2 BTBD1 AKAP8L TAF3 GNL2 BOD1L1 WDFY3 DMD CDH8 ZNF292

1.42e-0462913113Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

CASP8AP2 ATAD5 PCLO CEP290 ASH1L ZMYM2 GON4L ZDBF2 PIGT ERCC6L2 BOD1L1 DMD CDH8 SLC27A4 ZNF292

1.91e-0483113115Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasMESO-15 amniotic fluid MSC_vs_MESO-15 blastocyst-Confounder_removed-fold2.0_adjp0.05

DOCK3 BRIP1 SLC16A9 ATAD5 ACAD9 CEP290 LARS1 ZDBF2 MYEF2 DDX10 SLC38A1 NEDD9 NEO1 PTPN13 CFAP126 CDH20 TAF9B BOD1L1 PALLD EDRF1 CFAP97

2.79e-04147913121PCBC_ratio_MESO-15 amniotic fluid MSC_vs_MESO-15 blastocyst_cfr-2X-p05
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

CASP8AP2 TICRR EPHA6 CENPC RASSF2 ATAD5 CEP290 ZMYM2 ZDBF2 ZBED4 NRXN1 PTPRR BOD1L1 ATM DMD CMAHP ZNF292

2.85e-04106013117facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 CFAP47 EPHA6 ANK3 PCLO SLC38A1 DMD ZMAT1 FHIP1A ARAP2

3.13e-10189134107659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

NRAP ANK3 SLC38A1 MAST4 XIRP2 DMD FHIP1A PALLD FYB2 PHLDB2

3.13e-10189134100a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

NRAP ANK3 SLC38A1 MAST4 XIRP2 DMD FHIP1A PALLD PHLDB2

6.54e-09190134993c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 NRAP ANK3 MAST4 XIRP2 DMD FHIP1A PALLD FYB2

7.50e-091931349dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

RFC1 SPECC1 NEDD9 ANKRD11 BOD1L1 FH PALLD CFAP97 ZNF292

9.79e-091991349a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TICRR BRIP1 ATAD5 ZGRF1 POSTN FBN1 TENM3 FBXO43

1.02e-071871348e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TICRR BRIP1 ATAD5 ZGRF1 POSTN FBN1 TENM3 FBXO43

1.02e-071871348cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellCOPD-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

ZCWPW2 ANK3 SLC38A1 MAST4 CMAHP HYDIN PHLDB2 ARAP2

1.06e-071881348186fe1ea328c942910190a4240262c0d8642ea3b
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

DOCK3 NRAP ANK3 MAST4 PLCL2 FHIP1A PALLD FYB2

1.25e-071921348ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 NRAP ANK3 MAST4 XIRP2 DMD PALLD FYB2

1.41e-07195134875fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

PCLO CEP290 RFC1 SPECC1 ANKRD11 BOD1L1 CFAP97 ZNF292

1.65e-071991348c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CENPC ASH1L RESF1 ANKRD11 BOD1L1 ATM ARAP2 ZNF292

1.71e-07200134812f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CRISPLD2 FLNA ANK3 POSTN FBN1 LRP4 DMD PALLD

1.71e-07200134809537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 CASP8AP2 TICRR BRIP1 ATAD5 ZGRF1 ZNF732

8.19e-071691347e7514956b2e4298222ec443f98b2f5289451786e
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 NRAP ANK3 MAST4 XIRP2 DMD PALLD

1.34e-061821347287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNTL6 PCLO NEB NRXN1 XIRP2 DMD HYDIN

1.45e-0618413472cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNTL6 PCLO NEB NRXN1 XIRP2 DMD HYDIN

1.45e-061841347ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALNTL6 PCLO NEB NRXN1 XIRP2 DMD HYDIN

1.45e-0618413472b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

NRAP ANK3 MAST4 XIRP2 DMD PALLD FYB2

1.45e-061841347ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 ANK3 POSTN LRP4 HFM1 DMD PALLD

1.50e-0618513476712512100ccef456d2e2bd201d0987986c92ac9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARSJ ANK3 ABCB1 SLC38A1 PTPN13 PLCL2 FYB2

1.50e-061851347d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

NRAP ANK3 MAST4 XIRP2 DMD PALLD FYB2

1.50e-0618513476baccb26f999145e51b91d94315bf8d4655bef31
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARSJ ANK3 ABCB1 SLC38A1 PTPN13 PLCL2 FYB2

1.61e-061871347e3095455d2f255854f339f6b05fa87852af0700f
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 FLNA EPHA6 MAPT TENM3 PALLD PHLDB2

1.73e-061891347f7e2ee5047792ab9ef6472fa88e2d193cdea6fa0
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 FLNA EPHA6 MAPT TENM3 PALLD PHLDB2

1.73e-06189134763449d9f1e78ff2bc8786eb88a0d177fe30c7f4d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CRISPLD2 RASA3 SPECC1 DDX10 FBN1 TENM3 DMD

1.79e-0619013471121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CRISPLD2 RASA3 SPECC1 DDX10 FBN1 TENM3 DMD

1.79e-061901347048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 EPHA6 PCLO SLC38A1 DMD ZMAT1 FHIP1A

1.92e-061921347b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 CFAP47 EPHA6 SLC38A1 DMD FHIP1A ARAP2

2.06e-061941347f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 NRAP ANK3 DMD FHIP1A PALLD FYB2

2.13e-061951347f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA SPECC1 POSTN FBN1 TENM3 DMD PALLD

2.13e-06195134749c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA SPECC1 POSTN FBN1 TENM3 DMD PALLD

2.13e-061951347dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP47 ZCWPW2 ANK3 MAST4 CMAHP HYDIN FYB2

2.20e-061961347af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP47 ZCWPW2 ANK3 MAST4 CMAHP HYDIN FYB2

2.20e-0619613476d02d494196e3f857d53eea46d9419690d43beca
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 CEP290 MYEF2 DMD HYDIN FYB2 NEK11

2.28e-06197134774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CRISPLD2 FLNA SPECC1 FBN1 TENM3 DMD PALLD

2.28e-06197134780e153790cef37b743e22a7370ff5b3a6abf147d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CRISPLD2 RASA3 DDX10 FBN1 TENM3 DMD PALLD

2.35e-061981347a860246bcea847249a78fd2e86ed8e04371060db
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

CEP290 SPECC1 MYEF2 TAF3 PTPN13 ANKRD11 BOD1L1

2.35e-06198134776d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

RFC1 ANKRD11 BOD1L1 FH CFAP97 PHLDB2 ZNF292

2.43e-06199134719674e1eaeb51e4196d847cb62aa437c852951d3
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CRISPLD2 FLNA POSTN FBN1 LRP4 DMD PALLD

2.43e-06199134738cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

DOCK3 FLNA POSTN FBN1 LRP4 DMD PALLD

2.52e-0620013479d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DOCK3 FLNA ANK3 POSTN FBN1 DMD PALLD

2.52e-06200134787827041663013f5e7273168dc8709d69840e7ce
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

CRISPLD2 DOCK5 POSTN FBN1 LRP4 DMD PALLD

2.52e-062001347a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

DOCK3 CRISPLD2 FLNA POSTN FBN1 DMD PALLD

2.52e-0620013475ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DOCK3 FLNA ANK3 POSTN FBN1 DMD PALLD

2.52e-062001347c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DOCK3 FLNA ANK3 POSTN FBN1 DMD PALLD

2.52e-0620013478988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DOCK3 FLNA POSTN FBN1 LRP4 DMD PALLD

2.52e-06200134708bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK3 CRISPLD2 SLC16A9 FAT2 DMD PALLD

7.03e-0615313461524557514668f515ac1bbe847611f564b265b42
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A9 MAPT RASSF2 DOCK5 NRXN1 PLCL2

7.86e-061561346d72c2f5f72d269e29033f8728d924e0d4c8772c7
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A9 MAPT RASSF2 ZGRF1 DOCK5 NRXN1

8.45e-061581346d3446fc98eff09c3626b47a2c90d07cd985378b5
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A9 MAPT RASSF2 ZGRF1 DOCK5 NRXN1

8.45e-061581346df614450e10629dc9115d7365397663e82f9e48f
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

GALNTL6 EPHA6 NRXN1 XIRP2 DMD CDH8

8.76e-0615913465335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

TRAF1 ANK3 ASH1L SLC38A1 ATM ARAP2

9.75e-061621346b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZGRF1 ZNFX1 CFAP126 MAST4 TAF9B

1.18e-0598134595162072f3afc95e46f29db3d79ebd930bc09726
ToppCellLA-16._Neuronal|LA / Chamber and Cluster_Paper

ANK3 DOCK5 POSTN NRXN1 TENM3 ARAP2

1.20e-051681346c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCB1 SLC38A1 FAT2 PTPN13 PLCL2 FYB2

1.28e-051701346928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CRISPLD2 FBN1 TENM3 DMD ATP2B3 PALLD

1.33e-051711346972fab891135bd755d5526cbc5a963200067b0a6
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

ANK3 SLC38A1 FAT2 PTPN13 RESF1 ALPP

1.33e-05171134661318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CRISPLD2 FBN1 TENM3 DMD ATP2B3 PALLD

1.33e-0517113462a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAPT ATAD5 RFC1 POSTN NRXN1 DMD

1.37e-05172134603a0aff6b7971093a4347b5ed12546d78374c56f
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

ANK3 DOCK5 PTPN13 NRXN1 TENM3 ARAP2

1.42e-0517313466fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCellCF-Myeloid-Neutrophil|Myeloid / Disease state, Lineage and Cell class

RASSF2 ZNF429 NEDD9 DOCK5 RESF1 ZNF292

1.51e-0517513468020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 FLNA ZNF658 MYEF2 POSTN DMD

1.61e-051771346e65c0568dc5852108e9802273499bc7cf88fafab
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRISPLD2 ARSJ EPHA6 CDH20 CDH8 PHLDB2

1.66e-051781346b863fc85d2449f25e6cea289459a7bb1f89583fd
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRISPLD2 ARSJ EPHA6 CDH20 CDH8 PHLDB2

1.72e-051791346c815eb9f760fe4ca7a5e49beb224659f0b864f22
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CASP8AP2 TICRR BRIP1 ATAD5 ZGRF1 ZNF732

1.72e-05179134688d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellLV|World / Chamber and Cluster_Paper

VPS8 ABCB1 MAST4 XIRP2 PLCL2 FYB2

1.77e-0518013465ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRISPLD2 ARSJ EPHA6 CDH20 CDH8 PHLDB2

1.77e-0518013468923a42a6db9c6e9f3ce2ca9530e620dfea700ba
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRISPLD2 ARSJ CDH20 DMD CDH8 NEK11

1.77e-051801346b7513b9816a9cb9f3caaddb2a9fed0be1c7f9805
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRISPLD2 ARSJ CDH20 DMD CDH8 NEK11

1.77e-051801346f96c5be4705e3d338c0393d2885ac8d5beccd6fd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TICRR BRIP1 ATAD5 ZGRF1 ZNF732 FBXO43

1.77e-051801346401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 ABCB1 SLC38A1 PTPN13 PLCL2 FYB2

1.77e-051801346023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCellRA-16._Neuronal|RA / Chamber and Cluster_Paper

ANK3 DOCK5 PTPN13 NRXN1 TENM3 ARAP2

1.77e-0518013465842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCellRA-16._Neuronal|World / Chamber and Cluster_Paper

ANK3 DOCK5 PTPN13 NRXN1 TENM3 ARAP2

1.83e-0518113467d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 ABCB1 SLC38A1 PTPN13 PLCL2 FYB2

1.83e-051811346aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

TRAF1 ANK3 ASH1L SLC38A1 ATM ARAP2

1.83e-051811346f2315414e714ac86211546a935660c4be6e85f1b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TDRD15 ANK3 SLC38A1 PTPN13 PLCL2 FYB2

1.83e-051811346b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DOCK3 CFAP47 EPHA6 DMD FHIP1A ARAP2

1.95e-051831346c5b10571599dc26476170b54b53f09c23e6b3117
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARSJ ANK3 SLC38A1 PTPN13 PLCL2 FYB2

1.95e-051831346b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRISPLD2 FLNA POSTN DMD PALLD PHLDB2

1.95e-051831346af8d86f15a549064530d94bd47081daf59d58ecd
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK3 NRAP XIRP2 DMD PALLD FYB2

2.01e-051841346e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 ANK3 POSTN LRP4 DMD PALLD

2.07e-0518513463b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellControl-T_cells-CD8+_T_cells|Control / group, cell type (main and fine annotations)

RASA3 ABCB1 SLC38A1 RESF1 PLCL2 ATM

2.07e-05185134602ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARSJ ABCB1 NEDD9 WDFY3 HYDIN NEK11

2.13e-0518613465c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

ZCWPW2 ANK3 PTPN13 MAST4 CMAHP FHIP1A

2.13e-0518613469798428691408e17ff2af2fe2d1b345f074d67e4
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

ARSJ NEDD9 FHIP1A FYB2 PHLDB2 ARAP2

2.13e-05186134609d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellCOPD-Epithelial-Club|World / Disease state, Lineage and Cell class

ZCWPW2 ANK3 PTPN13 MAST4 CMAHP FHIP1A

2.13e-0518613463006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARSJ ANK3 SLC38A1 PTPN13 MAST4 FHIP1A

2.13e-051861346e83718fabb057100835d3357df407f283d23fe16
ToppCellCF|World / Disease state, Lineage and Cell class

TRAF1 RASSF2 NEDD9 DOCK5 RESF1 ZNF292

2.20e-051871346eec4d4e4a658e3a61c05745167a1a5e3d39bb43e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARSJ ANK3 ABCB1 SLC38A1 PLCL2 FYB2

2.20e-0518713462d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

ANK3 FAT2 PTPN13 MAST4 LRP4 FHIP1A

2.20e-0518713468407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 ANK3 ZMYM2 ZDBF2 ERCC6L2 PALLD

2.26e-0518813466468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 ANK3 ZMYM2 ZDBF2 ERCC6L2 PALLD

2.26e-0518813467a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 ANK3 ZMYM2 ZDBF2 ERCC6L2 PALLD

2.26e-0518813469cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK3 PCLO SLC38A1 DMD ZMAT1 FHIP1A

2.26e-0518813460d86044bc340e3efb90d0022dd299873639d831c
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK3 EPHA6 SLC38A1 DMD ZMAT1 FHIP1A

2.26e-0518813463cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 ABCB1 SLC38A1 PTPN13 PLCL2 FYB2

2.33e-0518913463a295c215b5c18e7c673f92b7af5be523421682c
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

MAST4 XIRP2 PLCL2 DMD PALLD FYB2

2.33e-0518913465e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 ABCB1 SLC38A1 PTPN13 PLCL2 FYB2

2.33e-051891346fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

ANK3 FAT2 PTPN13 PTPRR FHIP1A FYB2

2.33e-05189134684d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
DiseaseCREST syndrome (is_implicated_in)

CENPC FBN1

1.90e-0521292DOID:0060218 (is_implicated_in)
Diseaseprogression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian carcinoma

ARSJ EPHA6 DMD ARAP2

2.55e-05391294EFO_0001075, EFO_0004920, GO_0097328, MONDO_0009354
Diseasecarotid artery intima media thickness

TDRD15 VPS8 LINGO2 SRBD1 DOCK5 FBN1 PINX1 PALLD CDH8 NEK11

3.01e-0545012910EFO_0007117
Diseaseinfluenza A (H1N1)

CEP290 LINGO2 PTPRR DMD ARAP2

4.10e-05871295EFO_1001488
Diseaseleukemia (implicated_via_orthology)

NRAS ASH1L ATM

7.52e-05191293DOID:1240 (implicated_via_orthology)
DiseaseBone Marrow failure syndromes

SRP72 ERCC6L2

1.13e-0441292C2931245
DiseaseBone marrow failure syndrome 2

SRP72 ERCC6L2

1.13e-0441292C3810350
DiseaseBone marrow failure syndrome 1

SRP72 ERCC6L2

1.13e-0441292C3808553
Diseasehepatocellular carcinoma (is_implicated_in)

NRAS ABCB1 EFTUD2 SLC38A1 PTPN13 PINX1

1.49e-041811296DOID:684 (is_implicated_in)
DiseaseDuchenne and Becker Muscular Dystrophy

POSTN DMD

1.88e-0451292C3542021
DiseaseBecker Muscular Dystrophy

POSTN DMD

1.88e-0451292C0917713
DiseaseProgeria

ANK3 SPRTN

1.88e-0451292C0033300
DiseaseMuscular Dystrophy, Duchenne

POSTN DMD

2.81e-0461292C0013264
Diseaseskin pigmentation measurement

MYEF2 FBN1 CDH20 ANKRD11 HYDIN

3.48e-041371295EFO_0007009
Diseaseperipheral neuropathy

GALNTL6 XIRP2

3.93e-0471292EFO_0003100
Diseaserefractive error

ANK3 ZZEF1 SLC38A1 FBN1 PTPRR ATM ALPP

5.96e-043261297MONDO_0004892
Diseasemitral valve prolapse (is_implicated_in)

FLNA FBN1

6.69e-0491292DOID:988 (is_implicated_in)
Diseaseplasma renin activity measurement

TENM3 XIRP2

6.69e-0491292EFO_0006828
DiseaseNeurodevelopmental Disorders

ASH1L ANKRD11 WDFY3 ZNF292

7.54e-04931294C1535926
DiseaseAbnormality of refraction

DOCK3 BRIP1 ANK3 MAPT RASSF2 PCLO ZZEF1 FBN1 PTPRR PINX1

7.70e-0467312910HP_0000539
Diseasemean fractional anisotropy measurement

ZZEF1 DOCK5 ANKRD11 WDFY3

8.16e-04951294EFO_0008399
Diseasestatus epilepticus (biomarker_via_orthology)

ANK3 ABCB1 ATM DMD

9.89e-041001294DOID:1824 (biomarker_via_orthology)
Diseaseneurotic disorder

MAPT PCLO TENM3 PLCL2

1.03e-031011294EFO_0004257
Diseasemean corpuscular hemoglobin concentration

TICRR BRIP1 HECTD4 GON4L RFC1 NEB SPECC1 SLC38A1 NEO1 PLCL2 PINX1 HFM1 CMAHP

1.13e-03110512913EFO_0004528
Diseasebody weight

GALNTL6 ARSJ EPHA6 ATAD5 HECTD4 GON4L LINGO2 ZZEF1 SLC38A1 MAST4 NRXN1 PTPRR DMD NEK11

1.27e-03126112914EFO_0004338
DiseaseIGF-1 measurement

DOCK3 TICRR EPHA6 LINGO2 RESF1 PINX1 HFM1 CMAHP

1.41e-034881298EFO_0004627
Diseaseserum alanine aminotransferase measurement

BRIP1 NRAS RASA3 PCLO HECTD4 LINGO2 ABCB1 FBN1 CDH20 RESF1 PINX1

1.54e-0386912911EFO_0004735
Diseasepulse pressure measurement, social deprivation

FBN1 PLCL2

1.67e-03141292EFO_0005763, EFO_0009696
Diseaseleukemia

BRIP1 NRAS ATM

1.81e-03551293C0023418
Diseasehepcidin:ferritin ratio

FBN1 CMAHP ALPP

1.81e-03551293EFO_0007901
DiseaseAnilide use measurement

MAPT MSH5

1.92e-03151292EFO_0009938
Diseaseurate measurement

DOCK3 SHLD2 SLC16A9 ASH1L HECTD4 GON4L NEO1 NRXN1 LRP4 HFM1 CMAHP

1.95e-0389512911EFO_0004531
Diseasecolorectal cancer (is_implicated_in)

BRIP1 NRAS PTPN13 ATM

2.00e-031211294DOID:9256 (is_implicated_in)
DiseasePontoneocerebellar hypoplasia

PCLO TBC1D23

2.19e-03161292cv:C1261175
Diseasesystolic blood pressure, alcohol drinking

SLC16A9 HECTD4 FBN1 PINX1

2.45e-031281294EFO_0004329, EFO_0006335
Diseasecyclic adenosine monophosphate measurement

MAST4 ARAP2

2.47e-03171292EFO_0010473
Diseasebacteriemia

DOCK3 PALLD

2.47e-03171292EFO_0003033
Diseaselevel of Sterol ester (27:1/20:3) in blood serum

NRXN1 PARN

3.09e-03191292OBA_2045199
Diseasecommon carotid intimal medial thickness

TDRD15 ERCC6L2 PINX1

3.19e-03671293EFO_0004860
Diseaselung non-small cell carcinoma (is_implicated_in)

MSH5 ABCB1 ATM FH

3.29e-031391294DOID:3908 (is_implicated_in)
Diseaseascending aortic diameter

ATAD5 FBN1 PTPRR HYDIN

3.38e-031401294EFO_0021787
Diseasewellbeing measurement

PCLO LINGO2 MSH5 POSTN PTPRR PLCL2 LRP4 SPRTN CMAHP

3.45e-036921299EFO_0007869
DiseaseBREAST CANCER

BRIP1 ATM

3.77e-03211292114480
DiseaseSplenomegaly

NRAS MAPT

4.14e-03221292C0038002
Diseasebreast cancer, COVID-19

MAPT GON4L

4.14e-03221292MONDO_0007254, MONDO_0100096
Diseaseproprotein convertase subtilisin/kexin type 9 measurement

TDRD15 DDX10

4.14e-03221292EFO_0009312

Protein segments in the cluster

PeptideGeneStartEntry
KVPSSTVEYLKKHGI

AAMDC

76

Q9H7C9
SEHGLDNKIYPKNTK

ATAD5

1431

Q96QE3
KGSYETSKHEKQPPV

ASH1L

511

Q9NR48
HKYKSGIKSTETQPS

CFAP97

221

Q9P2B7
KEQTEKHKSVPGYLS

ANKRD11

921

Q6UB99
TCTKPAGKDLHVKYN

NEDD9

266

Q14511
KSYPETVLKHLKGVN

CCDC7

1086

Q96M83
EVSKQSLFYGKKQPH

GVINP1

826

Q7Z2Y8
QKAKYLPKLASGEHI

ACAD9

161

Q9H845
KEKLIYLEHSPNSEG

SPECC1

251

Q5M775
VLYKPHGKNKTAGET

BIVM

286

Q86UB2
IYANVHKTKKNDDPS

ARAP2

76

Q8WZ64
YESTRKENLPISGHK

FLG

86

P20930
EILSKGQHLYKEKPA

DMD

2381

P11532
LSKSEDPVHYKSLVG

CASP8AP2

1196

Q9UKL3
YEGLEKPESKTSIHN

ATP2B3

1126

Q16720
HFKYVGTKLPKQTAD

AKAP8L

416

Q9ULX6
DTKQAHELAKSYGIP

NRAS

126

P01111
KFKKTKYGSQEHPIG

RASA3

801

Q14644
VHTSGEKQKLKATDY

RASSF2

226

P50749
YPKGIHVETLETEKK

PARN

221

O95453
DSYSKSGHKPDNIKG

ABCB1

376

P08183
EILAKTPYGHEKKNL

ANO7

261

Q6IWH7
NPTVTHTKEPETYKK

SLC16A9

256

Q7RTY1
GTRSPHIETYLKKEK

GNL2

231

Q13823
KEDNPSGHTYTLVSK

MAGEB1

166

P43366
KAGELISEKKYRQHP

NRAP

951

Q86VF7
GELSVPEKYKSIHQI

EDRF1

571

Q3B7T1
VGYHGSEIKTPTLDK

ARSJ

91

Q5FYB0
KHISAPEKTYKGGSL

PCLO

3551

Q9Y6V0
KEKGPQNATDSYVHK

PLRG1

66

O43660
TVTGPLDYESKTKHV

FAT2

2226

Q9NYQ8
GKGKSESELPHKLYV

OR2M2

306

Q96R28
GKDVESYLQPKAKRH

PINX1

221

Q96BK5
KSERHGVQSLSKYKP

CRISPLD2

361

Q9H0B8
KNIKLYPGTGSKSDH

FAM214A

296

Q32MH5
HPKVYINLDKETKTG

NDUFS6

96

O75380
PEALKHQGYDTKSDI

NEK11

201

Q8NG66
VSYKISREHKGDTNP

HERVK_113

916

P63132
HKRASEKYKDNPSIS

LRRC37B

931

Q96QE4
GKHKNSIDLEYVPRK

LINGO2

571

Q7L985
YKSLPKLVHAKEGFQ

NRXN1

1036

Q9ULB1
PLYKLQKTECGSHTK

PRSS54

196

Q6PEW0
KYSKAGKEQHPVKVV

HECTD4

3331

Q9Y4D8
VSYKISREHKGDTNP

ERVK-6

916

Q9BXR3
KSGKPVFIYKHSQDI

PTPRR

36

Q15256
DHTGKSKIPKIYFGT

BRIP1

236

Q9BX63
QKYKNHIGTEIAPEK

HFM1

126

A2PYH4
KDGKQISPKSDHYTI

PALLD

1036

Q8WX93
LSKTYNVDKHVPDSG

ALPP

101

P05187
KKEKGPTLLYEHPET

FBXO43

96

Q4G163
EKTPSEDKLSVKHKY

BOD1L1

731

Q8NFC6
HPKGAKTQEKGAYES

ATM

291

Q13315
EKHDPLKNTQAKYGS

FHIP1A

41

Q05DH4
YKLTGESPIHQKKAA

HYDIN

3206

Q4G0P3
KDYINKHPGDAEKIT

DOCK3

1566

Q8IZD9
QNKSKKGIFPETYIH

DOCK5

51

Q9H7D0
VKHGELKVYKTLDTP

CENPC

851

Q03188
HYESKTKGTEKIIAE

CEP290

2191

O15078
KTGLKAHEPTYFTVD

FLNA

781

P21333
HFTKKKPVAGTYSLQ

FBN1

2816

P35555
KKSYTLKVEGANPHL

CDH20

346

Q9HBT6
PHIGYDKAAKIAKTA

FH

461

P07954
YGTKGLKKVVHETPA

BTBD1

436

Q9H0C5
SKSYKSKEPHELVGS

GON4L

1881

Q3T8J9
IAKGHLKKVTEQYPD

CTR9

396

Q6PD62
TTKKGFTPLHVAAKY

ANK3

561

Q12955
KPTKESISSHEGYTQ

CFAP126

26

Q5VTH2
HINKTTDLKTDYFKP

DRC7

491

Q8IY82
SEEKLSPSYGSDKKH

MAST4

1446

O15021
HKTSTGAPAAIKKLY

CAPG

126

P40121
VHEKAKYSTPATLEQ

DDX10

276

Q13206
HTDLDPGSKKIKYIL

CDH8

86

P55286
TYKEKVDADTLPHTK

ERCC6L2

1176

Q5T890
SKVYSKEITITNHGK

CFAP47

156

Q6ZTR5
ELPKLHNTYVGASEK

PTPN13

746

Q12923
HGIKFKPNQYTKIDT

EPHA6

136

Q9UF33
YEHSKPLKQEEATAT

MKRN1

106

Q9UHC7
ESHPSVYKVASGLKE

MSH5

236

O43196
YKDKHLVKSAEPGEQ

GALNTL6

31

Q49A17
HKVYEEKTKLPSSVE

TAF3

506

Q5VWG9
LDDAKIYSSHAKKPN

TAF9B

51

Q9HBM6
KKQKTDVSTEHPPFY

TRMT1L

621

Q7Z2T5
TTHQDDYPIKGLVKT

SAXO1

171

Q8IYX7
EGPKSKKYHSNNLVE

TDRD15

701

B5MCY1
HPYSKDKNSGAGEKK

MYEF2

81

Q9P2K5
YPHKVKTAQVSDERK

RFC1

266

P35251
LPNKDVYKKHSSLGQ

RESF1

1341

Q9HCM1
LGKEYTEKTPISEHA

LARS1

1131

Q9P2J5
KNTEKEPYSNHVFKV

FYB2

396

Q5VWT5
TKYSSQKVIGTPHAK

NEPRO

341

Q6NW34
SLEIIHKYEPSKEGQ

PLCL2

381

Q9UPR0
NGSHKYKGNSKDVKP

NEO1

1146

Q92859
KSTVPHFTEEEKYQK

SHLD2

126

Q86V20
KTKPNTKDHGYTTLA

SMARCB1

71

Q12824
YHQSKGDPTAKKGTS

VPS8

1341

Q8N3P4
YSLVDPEKAKALSKH

SRP72

491

O76094
QHAISTEKIKAKYPD

PHPT1

101

Q9NRX4
KKQHKEGLYLSDTLP

PHLDB2

886

Q86SQ0
EELEHVSAPYKTGSK

SRBD1

306

Q8N5C6
EKVPSYPKSTDHLEK

CCDC54

196

Q8NEL0
SHPSDKYIKETNTKN

CMAHP

261

Q9Y471
IGSQKPYRSEEKIKH

C12orf56

316

Q8IXR9
TAESKAEHKKLPQPY

XIRP2

2701

A4UGR9
SQLYAPVKTHKGEKS

ZNF561

266

Q8N587
KGYHKLLTKSVAETP

TICRR

956

Q7Z2Z1
NVGTKTYLTNHPAKK

WDFY3

1946

Q8IZQ1
YVHTLTITSKGKENK

PIGT

396

Q969N2
TITSKGKENKPSYIH

PIGT

401

Q969N2
PELHKTGTYKFQKTE

SLC27A4

586

Q6P1M0
SKKKHPELITFKYGN

TBC1D23

646

Q9NUY8
VSYKISREHKGDTNP

ERVK-8

916

P63133
IEENKPYSLKRGKHV

ZNF292

2351

O60281
KKTDESYHGRQKGPS

ZDBF2

2306

Q9HCK1
SKLQSPKHAYVKDDT

TRAF1

391

Q13077
AKTDHGAEIVYKSPV

MAPT

701

P10636
IEGKDTHYFIKTTTP

TENM3

2541

Q9P273
AHAQTEVAKKYGLKP

TOMM70

591

O94826
HQKTCGGTYIKIKEP

SPRTN

201

Q9H040
LENHPSVLKYEKIKG

ZNFX1

1091

Q9P2E3
SYKSPLIGHQKTDAE

ZNF658

476

Q5TYW1
EYKQVGSHPSFLKEV

ZMYM2

501

Q9UBW7
HEQKKSSKRTLPADY

UBP1

286

Q9NZI7
HTTDYVDEIKKISPK

VAT1

241

Q99536
YPLGKKHLISKDTEA

ZGRF1

766

Q86YA3
TLTQDKKIHTGEKPY

ZNF429

411

Q86V71
SPKGVEAAKELYTHL

ZZEF1

821

O43149
DLTLHKKVSAGEKPY

ZNF57

126

Q68EA5
VGHYSITLKPEKCKN

ZCWPW2

156

Q504Y3
NKYKTIHTGDKTPKC

ZNF732

546

B4DXR9
KPKIEHTYTGGVDSD

EFTUD2

446

Q15029
TEVIHGEPIIKKYTK

POSTN

721

Q15063
LQTHEKTHTGEKPYK

ZNF433

381

Q8N7K0
SHLEKKKCDEYIPGT

SLC38A1

56

Q9H2H9
EKQLPHSKKTYDSFQ

ZMAT1

291

Q5H9K5
SYKSPLIGHQKTDAE

ZNF658B

236

Q4V348
EKFYDSHPVAKKITS

ZBED4

646

O75132
GGPDHNYTKEKIKIV

LRP4

1796

O75096
KAGEILSEKKYRQHP

NEB

1706

P20929