Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin binding	SHROOM4 LMOD3 MYO3A COBLL1 PPP1R9B MYO16 TULP1	2.30e-04	479	52	7	GO:0003779
GeneOntologyMolecularFunction	actin filament binding	SHROOM4 MYO3A PPP1R9B MYO16 TULP1	3.06e-04	227	52	5	GO:0051015
GeneOntologyMolecularFunction	histone binding	PWWP2A BRD2 SRCAP HDGFL2 CBX8	6.19e-04	265	52	5	GO:0042393
GeneOntologyCellularComponent	postsynaptic density	ROCK2 DLGAP2 DLGAP1 PPP1R9B SLITRK3 LRRTM3	8.58e-04	451	52	6	GO:0014069
GeneOntologyCellularComponent	asymmetric synapse	ROCK2 DLGAP2 DLGAP1 PPP1R9B SLITRK3 LRRTM3	1.15e-03	477	52	6	GO:0032279
GeneOntologyCellularComponent	stereocilium tip	MYO3A PKHD1L1	1.36e-03	22	52	2	GO:0032426
GeneOntologyCellularComponent	postsynaptic specialization	ROCK2 DLGAP2 DLGAP1 PPP1R9B SLITRK3 LRRTM3	1.50e-03	503	52	6	GO:0099572
GeneOntologyCellularComponent	neuron to neuron synapse	ROCK2 DLGAP2 DLGAP1 PPP1R9B SLITRK3 LRRTM3	1.83e-03	523	52	6	GO:0098984
GeneOntologyCellularComponent	pole plasm	ANKRD34A HELZ	2.36e-03	29	52	2	GO:0045495
GeneOntologyCellularComponent	germ plasm	ANKRD34A HELZ	2.36e-03	29	52	2	GO:0060293
GeneOntologyCellularComponent	P granule	ANKRD34A HELZ	2.36e-03	29	52	2	GO:0043186
Domain	SAPAP	DLGAP2 DLGAP1	7.56e-05	5	52	2	IPR005026
Domain	GKAP	DLGAP2 DLGAP1	7.56e-05	5	52	2	PF03359
Domain	WH2	LMOD3 COBLL1	8.90e-04	16	52	2	PF02205
Domain	PWWP	PWWP2A HDGFL2	1.40e-03	20	52	2	SM00293
Domain	WH2_dom	LMOD3 COBLL1	1.54e-03	21	52	2	IPR003124
Domain	PWWP	PWWP2A HDGFL2	1.85e-03	23	52	2	PF00855
Domain	PWWP_dom	PWWP2A HDGFL2	1.85e-03	23	52	2	IPR000313
Domain	PWWP	PWWP2A HDGFL2	2.02e-03	24	52	2	PS50812
Domain	WH2	LMOD3 COBLL1	2.02e-03	24	52	2	PS51082
Domain	AT_hook	ASH1L SRCAP	2.55e-03	27	52	2	SM00384
Domain	AT_hook_DNA-bd_motif	ASH1L SRCAP	2.55e-03	27	52	2	IPR017956
Domain	SH2	RIN3 SH2D2A CLNK	3.56e-03	110	52	3	SM00252
Domain	SH2	RIN3 SH2D2A CLNK	3.65e-03	111	52	3	PS50001
Domain	SH2	RIN3 SH2D2A CLNK	3.75e-03	112	52	3	IPR000980
Domain	-	RIN3 SH2D2A CLNK	3.75e-03	112	52	3	3.30.505.10
Domain	BROMODOMAIN_1	BRD2 ASH1L	4.76e-03	37	52	2	PS00633
Domain	Myosin_head_motor_dom	MYO3A MYO16	5.01e-03	38	52	2	IPR001609
Domain	Bromodomain	BRD2 ASH1L	5.01e-03	38	52	2	PF00439
Domain	MYOSIN_MOTOR	MYO3A MYO16	5.01e-03	38	52	2	PS51456
Domain	Myosin_head	MYO3A MYO16	5.01e-03	38	52	2	PF00063
Domain	MYSc	MYO3A MYO16	5.01e-03	38	52	2	SM00242
Domain	BROMODOMAIN_2	BRD2 ASH1L	5.82e-03	41	52	2	PS50014
Domain	BROMO	BRD2 ASH1L	6.10e-03	42	52	2	SM00297
Domain	Bromodomain	BRD2 ASH1L	6.10e-03	42	52	2	IPR001487
Domain	-	BRD2 ASH1L	6.10e-03	42	52	2	1.20.920.10
Pathway	REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES	DLGAP2 DLGAP1 SLITRK3 LRRTM3	1.94e-05	67	34	4	MM15327
Pathway	REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES	DLGAP2 DLGAP1 SLITRK3 LRRTM3	5.45e-05	87	34	4	M27617
Pathway	REACTOME_NEUREXINS_AND_NEUROLIGINS	DLGAP2 DLGAP1 LRRTM3	6.06e-05	32	34	3	MM15326
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	DLGAP2 DLGAP1 RIN3 SYNJ2 SCARF2 TULP1 SOS1	6.75e-07	329	53	7	17474147
Pubmed	Genomic structure, chromosomal localization, and embryonic expression of the mouse homolog of PRCC, a gene associated with papillary renal cell carcinoma.	PRCC SH2D2A	2.28e-06	2	53	2	11435707
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TRERF1 ROCK2 DIP2B MYO3A BRD2 ZFP91 HELZ TNKS1BP1 SOS1	2.36e-06	774	53	9	15302935
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	ROCK2 CCDC8 CFAP91 SOWAHA PRCC COBLL1 ANKRD34A WDR83 HELZ TNKS1BP1 TULP1	4.00e-06	1321	53	11	27173435
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	DIP2B DLGAP1 NYAP2 SRGAP1 MYO16	2.08e-05	218	53	5	33378226
Pubmed	Learning and reaction times in mouse touchscreen tests are differentially impacted by mutations in genes encoding postsynaptic interacting proteins SYNGAP1, NLGN3, DLGAP1, DLGAP2 and SHANK2.	DLGAP2 DLGAP1	2.27e-05	5	53	2	33347690
Pubmed	Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse.	DLGAP2 DLGAP1	2.27e-05	5	53	2	15024750
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	DLGAP2 DLGAP1 SYNJ2 SOS1	2.55e-05	111	53	4	22558309
Pubmed	Defective central tolerance induction in NOD mice: genomics and genetics.	ASH1L SH2D2A	4.76e-05	7	53	2	15780994
Pubmed	SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.	DLGAP2 DLGAP1	4.76e-05	7	53	2	9115257
Pubmed	Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family.	DLGAP2 DLGAP1	4.76e-05	7	53	2	10527873
Pubmed	DAP-1, a novel protein that interacts with the guanylate kinase-like domains of hDLG and PSD-95.	DLGAP2 DLGAP1	4.76e-05	7	53	2	9286858
Pubmed	Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities.	DLGAP2 DLGAP1	6.34e-05	8	53	2	19640847
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ATMIN DIP2B SYNJ2 VSTM2L SBF2 ASH1L PPP1R9B SLITRK3 PRKRIP1 TET3	7.28e-05	1489	53	10	28611215
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	BRD2 SRCAP HDGFL2 CBX8	8.26e-05	150	53	4	28242625
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRERF1 VGF ROCK2 DIP2B DLGAP2 DLGAP1 NYAP2 PPP1R9B	9.86e-05	963	53	8	28671696
Pubmed	Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.	ASH1L SRCAP	2.05e-04	14	53	2	28263302
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ATMIN RIN3 BRD2 SBF2 ANKRD34A TNKS1BP1 PRKRIP1 SRCAP	2.52e-04	1105	53	8	35748872
Pubmed	Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.	LMOD3 ASH1L	2.70e-04	16	53	2	16096065
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	NYAP2 BRD2 PRCC PPP1R9B PRKRIP1	2.76e-04	378	53	5	34315543
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	BRD2 SRGAP1 SBF2 TNKS1BP1 HDGFL2 CBX8	2.99e-04	601	53	6	33658012
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DIP2B CCDC8 SYNJ2 SRGAP1 COBLL1 HELZ TNKS1BP1	3.18e-04	861	53	7	36931259
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	PWWP2A BRD2 ZFP91 SRCAP HDGFL2 CBX8	3.18e-04	608	53	6	36089195
Pubmed	Identification of tooth-specific downstream targets of Runx2.	ROCK2 SOS1	3.43e-04	18	53	2	11722849
Pubmed	Phospho-tyrosine dependent protein-protein interaction network.	RIN3 VSTM2L WDR83 SH2D2A CLNK	4.01e-04	410	53	5	25814554
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	PWWP2A BRD2 ZFP91 PPP1R9B SRCAP CBX8	4.35e-04	645	53	6	25281560
Pubmed	Identification of novel ARF binding proteins by two-hybrid screening.	ZFP91 PPP1R9B	4.70e-04	21	53	2	16582619
Pubmed	NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons.	NYAP2 MYO16	5.16e-04	22	53	2	21946561
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	ROCK2 DIP2B DLGAP2 DLGAP1	5.88e-04	251	53	4	27507650
Pubmed	Proteomic profiling of Myc-associated proteins.	RIN3 HELZ SEC31B	7.13e-04	114	53	3	21150319
Pubmed	ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.	ZNF750 TNKS1BP1	7.23e-04	26	53	2	25228645
Pubmed	A human MAP kinase interactome.	DLGAP1 SYNJ2 COBLL1 HELZ SOS1	8.62e-04	486	53	5	20936779
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ROCK2 SHROOM4 PWWP2A COBLL1 SBF2	9.19e-04	493	53	5	15368895
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	PWWP2A CCDC8 SOWAHA BRD2 CBX8	9.36e-04	495	53	5	27705803
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ARHGAP5 CCDC8 BRD2 SBF2 HELZ PPP1R9B CBX8	1.02e-03	1049	53	7	27880917
Pubmed	Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.	DLGAP2 DLGAP1 PPP1R9B	1.07e-03	131	53	3	28634551
Pubmed	Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.	RIN3 TET3	1.10e-03	32	53	2	21546767
Pubmed	Human transcription factor protein interaction networks.	TRERF1 CCDC8 BRD2 PRCC ZFP91 WDR83 HELZ SRCAP	1.36e-03	1429	53	8	35140242
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TRERF1 ZNF750 BRD2 ASH1L SRCAP PKHD1L1	1.40e-03	808	53	6	20412781
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SOWAHA BRD2 ZFP91 ASH1L HELZ SRCAP SOS1	1.46e-03	1116	53	7	31753913
Interaction	ARHGAP26 interactions	ARHGAP5 NYAP2 SRGAP1 MYO16 TULP1 SOS1	7.18e-07	120	53	6	int:ARHGAP26
Interaction	RAPGEF4 interactions	DLGAP1 SRGAP1 PPP1R9B SOS1	8.97e-06	50	53	4	int:RAPGEF4
Interaction	VASP interactions	DIP2B ARHGAP5 SYNJ2 COBLL1 PPP1R9B TNKS1BP1 HS1BP3	1.14e-05	294	53	7	int:VASP
Interaction	NCKAP1 interactions	ROCK2 DLGAP1 RIN3 NYAP2 PPP1R9B MYO16	2.25e-05	218	53	6	int:NCKAP1
Interaction	DLG3 interactions	DLGAP2 DLGAP1 COBLL1 ZFP91 PPP1R9B	2.40e-05	131	53	5	int:DLG3
Interaction	PACSIN3 interactions	CCDC8 RIN3 COBLL1 CLNK SOS1	2.40e-05	131	53	5	int:PACSIN3
Cytoband	3q26.1	OTOL1 SLITRK3	4.85e-04	28	53	2	3q26.1
Cytoband	1q21.1	PRCC ANKRD34A	2.37e-03	62	53	2	1q21.1
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP5 SRGAP1	4.21e-03	50	35	2	721
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	CCDC8 PPP1R9B MYO16	5.10e-03	181	35	3	694
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ROCK2 SBF2 SOS1	7.30e-03	206	35	3	682
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 VGF DLGAP2 NYAP2 EGR3	2.51e-06	182	53	5	d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 VGF DLGAP2 NYAP2 EGR3	2.51e-06	182	53	5	6cde859edfe7607bd7ada89d20258413d06f4207
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ROCK2 DLGAP1 SYNJ2 HELZ SOS1	3.26e-06	192	53	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	ROCK2 DLGAP1 SYNJ2 HELZ SOS1	3.35e-06	193	53	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Transverse-T_cell-Tfh\|T_cell / Region, Cell class and subclass	DLGAP1 SRGAP1 CLNK TET3 CBX8	3.89e-06	199	53	5	33ffea12b8228e0b5bd8942531c3b21d24224725
ToppCell	primary_visual_cortex\|World / Per Region, Lineage, Cell class, Cell type, Cell subtype	VGF EGR3 IL17RA TET3	2.40e-05	141	53	4	605d7b28e99c943f64b4095855a6f9f70e92cb09
ToppCell	facs-Lung-Endomucin-24m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRGAP1 COBLL1 PRKRIP1 HDGFL2	4.13e-05	162	53	4	497ae9f86a5e7946d0fde932b35719a382a6b691
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RIN3 SCARF2 CLNK TET3	4.13e-05	162	53	4	64353d33af0e82ebb7cf2bba74d52ca0586a58fc
ToppCell	facs-Lung-Endomucin-24m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRGAP1 COBLL1 PRKRIP1 HDGFL2	4.13e-05	162	53	4	7b2949eba2b4aea239d96ed82aafab13b07624eb
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RIN3 SCARF2 CLNK TET3	4.23e-05	163	53	4	9f5facfa1864eb63e2f8022ad7379d9252b7a254
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIN3 ANKRD34A SH2D2A CLNK	4.76e-05	168	53	4	2765d98f0b7f6861d662937535e051d41dba3500
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LMOD3 SRGAP1 COBLL1 MYO16	5.71e-05	176	53	4	95d5a4fdff1b9c715636684d22e06f8727ac0e7a
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LMOD3 SRGAP1 COBLL1 MYO16	6.09e-05	179	53	4	3b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LMOD3 SRGAP1 COBLL1 MYO16	6.36e-05	181	53	4	7704f236831cffe4f2a75d4c461eb88b4177e206
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SRGAP1 PPP1R9B IL17RA TET3	7.07e-05	186	53	4	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VGF MYO3A NYAP2 MYO16	7.07e-05	186	53	4	310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	VGF NYAP2 VSTM2L ANKRD34A	7.68e-05	190	53	4	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	Adult-Immune-monocyte-D175\|Adult / Lineage, Cell type, age group and donor	TRERF1 RIN3 EGR3 IL17RA	7.83e-05	191	53	4	cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VGF MYO3A NYAP2 MYO16	7.83e-05	191	53	4	fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGF DLGAP2 DLGAP1 SLITRK3	8.15e-05	193	53	4	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGF DLGAP2 DLGAP1 SLITRK3	8.15e-05	193	53	4	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGF DLGAP2 DLGAP1 SLITRK3	8.15e-05	193	53	4	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROCK2 ARHGAP5 ASH1L TET3	8.32e-05	194	53	4	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 SRGAP1 LRRTM3 MYO16	8.32e-05	194	53	4	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 SRGAP1 LRRTM3 MYO16	8.32e-05	194	53	4	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGF DLGAP2 NYAP2 EGR3	8.49e-05	195	53	4	ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell	COVID-19-Myeloid-Monocytes\|COVID-19 / group, cell type (main and fine annotations)	RIN3 SBF2 IL17RA TET3	8.65e-05	196	53	4	04d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RIN3 SBF2 IL17RA TET3	8.65e-05	196	53	4	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRERF1 ANKRD34A SH2D2A CLNK	9.00e-05	198	53	4	90863377ed36afc30bc1a068612ad1adc77af5a8
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRERF1 RIN3 EGR3 CLNK	9.00e-05	198	53	4	fa5c15a656d4132950092919600e270f1fd79abf
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DLGAP1 BRD2 SH2D2A CLNK	9.00e-05	198	53	4	d021d0edb6aba2f15c51a3ec4e08c7233d0c1962
ToppCell	Transverse-T_cell-Tfh\|Transverse / Region, Cell class and subclass	DLGAP1 SRGAP1 TET3 CBX8	9.18e-05	199	53	4	cbef8f95edf2e86e16c448a76068d7ed8f6b7748
ToppCell	Transverse-(1)_T_cell-(16)_Tfh\|Transverse / shred on region, Cell_type, and subtype	DLGAP1 SRGAP1 TET3 CBX8	9.18e-05	199	53	4	aa31e26d48066f865ca33251a33a28934c0a7a44
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD56bright\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRERF1 RIN3 SH2D2A CLNK	9.36e-05	200	53	4	1db27223e307efca97502fca40ec5e4f8eea512b
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-gdT\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TRERF1 RIN3 VSTM2L CLNK	9.36e-05	200	53	4	9996803c35444d32b76ab78b716674c3743f155a
Disease	colorectal cancer	DIP2B DLGAP2 DLGAP1 RIN3 PTCHD3 SYNJ2 SRGAP1 SBF2 MYO16	1.18e-06	604	53	9	MONDO_0005575
Disease	testosterone measurement	SHROOM4 DIP2B DLGAP1 NYAP2 COBLL1 SBF2 TNKS1BP1 SRCAP MYO16 CBX8 SOS1	1.35e-05	1275	53	11	EFO_0004908
Disease	body mass index, fasting blood insulin measurement	NYAP2 PTCHD3 COBLL1	2.87e-05	33	53	3	EFO_0004340, EFO_0004466
Disease	body fat percentage, fasting blood insulin measurement	NYAP2 COBLL1	4.73e-05	6	53	2	EFO_0004466, EFO_0007800
Disease	leptin measurement, type 2 diabetes mellitus	NYAP2 COBLL1	3.74e-04	16	53	2	EFO_0005000, MONDO_0005148
Disease	body mass index, type 2 diabetes mellitus	NYAP2 COBLL1	3.74e-04	16	53	2	EFO_0004340, MONDO_0005148
Disease	monounsaturated fatty acids; 16:1, 18:1 measurement	NYAP2 COBLL1 SEC31B	3.78e-04	78	53	3	EFO_0022187
Disease	body fat percentage, type 2 diabetes mellitus	NYAP2 COBLL1	4.23e-04	17	53	2	EFO_0007800, MONDO_0005148
Disease	BMI-adjusted fasting blood insulin measurement	NYAP2 COBLL1	4.75e-04	18	53	2	EFO_0008037
Disease	body mass index, high density lipoprotein cholesterol measurement	NYAP2 COBLL1	5.31e-04	19	53	2	EFO_0004340, EFO_0004612
Disease	triglyceride measurement, body mass index	NYAP2 COBLL1	5.31e-04	19	53	2	EFO_0004340, EFO_0004530
Disease	colorectal cancer, inflammatory bowel disease	DLGAP2 PTCHD3	5.31e-04	19	53	2	EFO_0003767, MONDO_0005575
Disease	Neurodevelopmental Disorders	DLGAP1 ASH1L SRCAP	6.33e-04	93	53	3	C1535926
Disease	triglyceride measurement, body fat percentage	NYAP2 COBLL1	6.50e-04	21	53	2	EFO_0004530, EFO_0007800
Disease	body fat percentage, high density lipoprotein cholesterol measurement	NYAP2 COBLL1	9.25e-04	25	53	2	EFO_0004612, EFO_0007800
Disease	eosinophil count	TRERF1 DIP2B RIN3 SBF2 TNKS1BP1 IL17RA TET3 MYO16 TULP1	1.22e-03	1488	53	9	EFO_0004842
Disease	severe acute respiratory syndrome, COVID-19	DLGAP2 DLGAP1 RIN3 SYNJ2 SCARF2	1.23e-03	447	53	5	EFO_0000694, MONDO_0100096
Disease	HbA1c measurement	DIP2B NYAP2 COBLL1 SBF2 ASH1L SOS1	1.29e-03	675	53	6	EFO_0004541
Disease	rheumatoid arthritis	DLGAP2 DLGAP1 RIN3 CLNK TET3	1.42e-03	462	53	5	EFO_0000685
Disease	platelet crit	PWWP2A DIP2B RIN3 NYAP2 SH2D2A HDGFL2 CBX8	1.51e-03	952	53	7	EFO_0007985
Disease	autoimmune thyroid disease	SH2D2A CLNK TULP1	1.52e-03	126	53	3	EFO_0006812
Disease	non-high density lipoprotein cholesterol measurement	DIP2B NYAP2 COBLL1 HELZ HDGFL2 TULP1	1.70e-03	713	53	6	EFO_0005689
Disease	gluteofemoral adipose tissue measurement	NYAP2 COBLL1 TULP1	1.74e-03	132	53	3	EFO_0803317

Protein segments in the cluster

Peptide	Gene	Start	Entry
PREKKPPRPPKKKYQ	ASH1L	1976	Q9NR48
PTRPFNRKRFAPPKP	ALPK3	676	Q96L96
DKKERRAPPPVPKKP	DLGAP1	906	O14490
RKEERKVPPPIPKKP	DLGAP2	981	Q9P1A6
APARRKPKAKAPLPP	COBLL1	11	Q53SF7
LPKPPRHPPKPLKRL	ANKRD34A	231	Q69YU3
KKPPRFLQRNPIPQP	CFAP91	461	Q7Z4T9
PAADLIPPPLKPRKV	IL17RA	366	Q96F46
PPIQKPKILRPALLP	SBF2	866	Q86WG5
KTLKPVPRNRPPPLV	LMOD3	516	Q0VAK6
SPRKQPPPKPKRDPN	MYO16	1291	Q9Y6X6
LPRKRLPQLYKPPTP	DIP2B	1136	Q9P265
RRQPPPKPKRDPSTK	NYAP2	136	Q9P242
YSKKIPPPKPKRNPN	NYAP2	186	Q9P242
RAPPKPRPPPEQAKK	HELZ	1901	P42694
KKPPRGRKPAEKPLP	HDGFL2	271	Q7Z4V5
EKPLPKPRGRKPKPE	HDGFL2	281	Q7Z4V5
PPRPKKEPQTLVIPK	PRKRIP1	11	Q9H875
TPPRYPQKLLLPKPK	ATMIN	286	O43313
KPPVAAKPVIPRKPA	HS1BP3	331	Q53T59
AKPVIPRKPAVPPKA	HS1BP3	336	Q53T59
PKPRKELPDPSQRPL	CBX8	201	Q9HC52
LPQPPLTLKPIRPRK	EGR3	246	Q06889
PPQPPKKPKEPRVRR	CCDC8	66	Q9H0W5
PKPRPGPEQKPKLTK	PTCHD3	6	Q3KNS1
KPFPPPNIPIKFEKI	OTOL1	351	A6NHN0
RTAKQPPVPPPRKKR	RIN3	451	Q8TB24
IPQPPPRKIKRPKRK	PWWP2A	286	Q96N64
PNVPPKPQKHRKSRP	SRGAP1	481	Q7Z6B7
KPPALRPKPAVLPKT	SRGAP1	1051	Q7Z6B7
KRKKNAPPEPVPPPR	VGF	481	O15240
PPLGLPKPKKRKEPV	PRCC	131	Q92733
QLLRPKPPIPAKPQL	SH2D2A	241	Q9NP31
PPLVPKVPPRRKKSA	SYNJ2	1326	O15056
PKPTFKPKLPRPKHE	LRRTM3	376	Q86VH5
KPKLPRPKHESKPPL	LRRTM3	381	Q86VH5
KQPKPTKQPRTPRPP	SLITRK3	331	O94933
LLGARKKAFPPPRPP	SHROOM4	1091	Q9ULL8
ERNHKVPPPIKPKPV	ARHGAP5	1031	Q13017
APLIPPLKKPPKWIR	SEC31B	371	Q9NQW1
LKRLPKVPEPPRPKG	SRCAP	121	Q6ZRS2
IEPRNPKPLPRFPKK	SOS1	1016	Q07889
PRAPRPPQPKKSKKA	BRD2	576	P25440
ASVRKNKIPLPPPRP	CLNK	151	Q7Z7G1
SPDPPPKPLRVRNKE	TULP1	171	O00294
ERKPKKPHYIPRPPG	ZNF750	6	Q32MQ0
FVVLRKKPRPPEPEP	SOWAHA	76	Q2M3V2
RRKPPPPDPATKPKV	SCARF2	656	Q96GP6
AKPPVKPKPRALPAK	TNKS1BP1	36	Q9C0C2
KPKPRALPAKPALPA	TNKS1BP1	41	Q9C0C2
KKIPKKPPAPDPFAR	ROCK2	1346	O75116
FPVHPPSRKPIPKKR	PKHD1L1	3011	Q86WI1
PVPRLPDRPPKEKKK	TET3	566	O43151
PKPRPPELPQKRLKT	WDR83	6	Q9BRX9
SPRLPKRRKKPPIQY	ZFP91	296	Q96JP5
PAPPPPKPGKELRKR	VSTM2L	181	Q96N03
KKKFRHRPEPLFIPP	TRERF1	651	Q96PN7
KIPRNPPPKLRQPEL	MYO3A	241	Q8NEV4
EPKILRPPRRPRKPK	MYO3A	1486	Q8NEV4
ARPPPKPREVRKIKP	PPP1R9B	286	Q96SB3