Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionArp2/3 complex binding

WASF1 WASF3

8.13e-0516172GO:0071933
GeneOntologyMolecularFunctionprotein kinase A regulatory subunit binding

WASF1 WASF3

2.02e-0425172GO:0034237
GeneOntologyMolecularFunctionprotein kinase A binding

WASF1 WASF3

1.10e-0358172GO:0051018
GeneOntologyBiologicalProcesspositive regulation of Arp2/3 complex-mediated actin nucleation

WASF1 WASF3

1.79e-058172GO:2000601
GeneOntologyBiologicalProcesspositive regulation of actin nucleation

WASF1 WASF3

5.78e-0514172GO:0051127
GeneOntologyBiologicalProcessmodification of postsynaptic actin cytoskeleton

WASF1 WASF3

1.75e-0424172GO:0098885
GeneOntologyBiologicalProcesspositive regulation of myelination

DICER1 WASF3

2.56e-0429172GO:0031643
GeneOntologyBiologicalProcessregulation of Arp2/3 complex-mediated actin nucleation

WASF1 WASF3

2.93e-0431172GO:0034315
GeneOntologyBiologicalProcessactin filament polymerization

WASF1 SPTAN1 WASF3

4.76e-04190173GO:0030041
GeneOntologyBiologicalProcessregulation of actin nucleation

WASF1 WASF3

5.14e-0441172GO:0051125
GeneOntologyBiologicalProcessmodification of postsynaptic structure

WASF1 WASF3

5.40e-0442172GO:0099010
GeneOntologyCellularComponentpostsynapse

PPP1R2 GRM5 WASF1 KCNH1 DICER1 SPTAN1 WASF3

8.05e-061018177GO:0098794
GeneOntologyCellularComponentSCAR complex

WASF1 WASF3

4.09e-0512172GO:0031209
GeneOntologyCellularComponentglial cell projection

GRM5 WASF3

6.59e-0447172GO:0097386
DomainSCAR/WAVE_fam

WASF1 WASF3

2.34e-063172IPR028288
DomainWH2

WASF1 WASF3

7.05e-0514172SM00246
DomainWH2

WASF1 WASF3

9.29e-0516172PF02205
DomainWH2_dom

WASF1 WASF3

1.62e-0421172IPR003124
DomainWH2

WASF1 WASF3

2.13e-0424172PS51082
DomainTPR_8

TMTC3 FKBP5

1.05e-0353172PF13181
DomainTPR_1

TMTC3 FKBP5

2.98e-0390172PF00515
DomainTPR_1

TMTC3 FKBP5

2.98e-0390172IPR001440
DomainTPR

TMTC3 FKBP5

6.02e-03129172SM00028
DomainTPR_repeat

TMTC3 FKBP5

6.38e-03133172IPR019734
DomainTPR-contain_dom

TMTC3 FKBP5

8.05e-03150172IPR013026
DomainTPR

TMTC3 FKBP5

9.67e-03165172PS50005
DomainTPR_REGION

TMTC3 FKBP5

9.67e-03165172PS50293
Domain-

TMTC3 FKBP5

1.49e-022071721.25.40.10
DomainTPR-like_helical_dom

TMTC3 FKBP5

1.86e-02233172IPR011990
PathwayBIOCARTA_ACTINY_PATHWAY

WASF1 WASF3

2.98e-0510122MM1528
PathwayBIOCARTA_ACTINY_PATHWAY

WASF1 WASF3

4.36e-0512122M7825
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_TO_RAC_SIGNALING_PATHWAY

WASF1 WASF3

1.25e-0420122M47737
PathwayKEGG_MEDICUS_REFERENCE_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY

WASF1 WASF3

1.97e-0425122M47716
PathwayKEGG_MEDICUS_PATHOGEN_SHIGELLA_IPGD_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY

WASF1 WASF3

2.66e-0429122M47717
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY

WASF1 WASF3

2.85e-0430122M47738
PathwayREACTOME_RHO_GTPASES_ACTIVATE_WASPS_AND_WAVES

WASF1 WASF3

3.67e-0434122MM15265
PathwayREACTOME_RHO_GTPASES_ACTIVATE_WASPS_AND_WAVES

WASF1 WASF3

4.12e-0436122M27549
PathwayKEGG_ADHERENS_JUNCTION

WASF1 WASF3

1.69e-0373122M638
PathwayKEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS

WASF1 WASF3

2.90e-0396122M16121
PathwayREACTOME_SIGNALING_BY_VEGF

WASF1 WASF3

3.33e-03103122MM14752
PathwayREACTOME_SIGNALING_BY_VEGF

WASF1 WASF3

3.52e-03106122M27077
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

WASF1 WASF3

4.06e-03114122MM14814
PathwayREACTOME_PARASITE_INFECTION

WASF1 WASF3

4.20e-03116122M29843
PathwayWP_FRAGILE_X_SYNDROME

GRM5 DICER1

4.56e-03121122M39804
PathwayREACTOME_MATERNAL_TO_ZYGOTIC_TRANSITION_MZT

DPPA4 DICER1

5.09e-03128122M48019
PathwayREACTOME_RHO_GTPASE_CYCLE

WASF1 SPTAN1 WASF3

5.35e-03439123MM15595
Pubmed

Rapid WAVE dynamics in dendritic spines of cultured hippocampal neurons is mediated by actin polymerization.

WASF1 WASF3

2.25e-07217216190876
Pubmed

The Association Between WAVE1 and -3 and the ARP2/3 Complex in PC 3 Cells.

WASF1 WASF3

2.25e-07217226977009
Pubmed

SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development.

WASF1 WASF3

6.74e-0731729732292
Pubmed

WAVE/Scars in platelets.

WASF1 WASF3

6.74e-07317215280206
Pubmed

Characterization of the WAVE1 knock-out mouse: implications for CNS development.

WASF1 WASF3

6.74e-07317212716942
Pubmed

Genomic organization and expression profile of the human and mouse WAVE gene family.

WASF1 WASF3

6.74e-07317212856283
Pubmed

Expression and subcellular localization of WAVE isoforms in the megakaryocyte/platelet lineage.

WASF1 WASF3

6.74e-07317215670045
Pubmed

Neutrophils establish rapid and robust WAVE complex polarity in an actin-dependent fashion.

WASF1 WASF3

1.35e-06417219200726
Pubmed

The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery.

WASF1 WASF3

1.35e-06417217664349
Pubmed

FBP11 regulates nuclear localization of N-WASP and inhibits N-WASP-dependent microspike formation.

WASF1 WASF3

2.25e-06517214697212
Pubmed

WAVE2 is required for directed cell migration and cardiovascular development.

WASF1 WASF3

2.25e-06517212879075
Pubmed

HIV-1 reprograms the migration of macrophages.

WASF1 WASF3

3.37e-06617225527710
Pubmed

HIV-1 Nef drives macrophages into hiding.

WASF1 WASF3

3.37e-06617225745180
Pubmed

Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex.

WASF1 WASF3

6.29e-06817210381382
Pubmed

Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex.

WASF1 WASF3

6.29e-06817211146629
Pubmed

Neurodevelopmental disorder-associated CYFIP2 regulates membraneless organelles and eIF2α phosphorylation via protein interactors and actin cytoskeleton.

WASF1 WASF3

8.08e-06917238981622
Pubmed

WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination.

WASF1 WASF3

1.75e-051317216723544
Pubmed

USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling.

DICER1 FKBP5

1.75e-051317228363942
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

DICER1 ZC3H15 C16orf96 SPTAN1 SERPINB2

1.94e-0572417536232890
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

PPP1R2 DICER1 ZC3H15 FKBP5

4.92e-0543217423455922
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

PTPRG KCNH1 DICER1

7.55e-0517117320201926
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PPP1R2 PTPRG WASF1 FKBP5 SPTAN1

1.13e-04104917527880917
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

PPP1R2 WASF1 ZC3H15 SPTAN1

2.30e-0464517425281560
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

GRM5 WASF1 SPTAN1

2.34e-0425117327507650
Pubmed

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.

WASF1 SPTY2D1

3.17e-045417226288249
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

GRM5 WASF1 SPTAN1

3.26e-0428117328706196
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

PPP1R2 TMTC3 DICER1 FKBP5

3.74e-0473317434672954
Pubmed

Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.

GRM5 FKBP5

4.88e-046717220398908
Pubmed

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.

WASF1 WASF3

4.88e-046717221875946
InteractionTMTC1 interactions

TMTC3 DPPA4

3.00e-0510172int:TMTC1
InteractionCDK5 interactions

PPP1R2 GRM5 WASF1 FKBP5

4.27e-05242174int:CDK5
GeneFamilyWiskott-Aldrich Syndrome protein family

WASF1 WASF3

4.82e-051612214
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TMTC3 FKBP5

2.54e-03115122769
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R2 GRM5

6.16e-03181122694
ToppCellMonocytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

WASF1 FKBP5 SERPINB2

2.79e-05158173c3096b3a914a1a15ebe3664613e94b951f8555fc
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRG KCNH1 FKBP5

3.47e-0517017367d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRG KCNH1 FKBP5

3.47e-051701738e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

GRM5 DICER1

8.44e-04114172656072c25258d4c00f24f6ba17de6a5db891e7be
ToppCelldroplet-Heart-nan-18m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTAN1 WASF3

1.03e-03126172de09142c12fd2ad6ecc3e7707015582f751eb426
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM5 KCNH1

1.27e-031401727ca49bd7ba9381e75c10f888775df17e5d46804d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM5 KCNH1

1.27e-031401721a31bc33d5723b9bc528cc0047ca5f4c80531c7a
ToppCellpdx-Tumor_cells-T9|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ZC3H15 SPTAN1

1.34e-031441720b94d978262a826c9254145aa98c6c30240243f9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRM5 DPPA4

1.51e-03153172499670e716fc85ce76630fc813cec86f8419f2a1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GRM5 C16orf96

1.51e-03153172d6526d17826470534b766df144c74e73eb83fdad
ToppCell356C-Myeloid-Dendritic-pDC|356C / Donor, Lineage, Cell class and subclass (all cells)

WASF1 DPPA4

1.57e-03156172d9d87368e43b24952e70f31f38425e15b716ff5b
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FKBP5 WASF3

1.59e-031571728c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FKBP5 WASF3

1.59e-03157172ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FKBP5 WASF3

1.59e-03157172008f938a338f43c3251dcac574f1b4f689926c71
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh|GI_large-bowel / Manually curated celltypes from each tissue

PPP1R2 FKBP5

1.71e-031631724104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCellMultiple_Sclerosis-Other-HSPC|Multiple_Sclerosis / Disease, Lineage and Cell Type

DPPA4 C16orf96

1.73e-031641726af5529507d695b347adee4be5ead70f56c9cf55
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WASF1 DPPA4

1.75e-03165172e2a70dd5870fe8708bf630ed3e6eb3f295df0cdf
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

PTPRG SPTAN1

1.82e-0316817200646601548b0fee42ae16bfa5e93603bc7c5129
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

GRM5 DPPA4

1.82e-03168172dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCellMonocytes-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

DPPA4 FKBP5

1.82e-031681729ea3c682ce4e98f1a3303f99b4c63c2cf8863abc
ToppCell343B-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PTPRG DPPA4

1.84e-03169172632aa3ab39ec87bafcefec6cddf71129a054d3b0
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

PTPRG FKBP5

1.84e-031691726373562ab3b1765060212a6a53d6543e7e942e80
ToppCellBL-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPRG KCNH1

1.86e-03170172b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTD1 SERPINB2

1.86e-0317017245de83a2231208b8e1f21061d0b91644b4a3ba93
ToppCellmild-Others-CD34+_GATA2+_cells|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

WASF1 DPPA4

1.90e-03172172379f6f271e653d5e404851e51a189bd582bb0f43
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPRG KCNH1

1.95e-03174172b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRG KCNH1

1.95e-03174172f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPRG KCNH1

1.95e-03174172cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PTPRG KCNH1

1.95e-0317417271730503be3d9c839c4c9e950145e2101d682a1c
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

PTPRG KCNH1

1.95e-03174172ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

WASF1 FKBP5

1.97e-031751726374ab186d7ccf7f6dfb858267edba8962789e15
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DTD1 FKBP5

1.99e-03176172437cfc5e06416bb0fc76d1f9dc106f74e279e880
ToppCell3'_v3-Lung-Hematopoietic_progenitors|Lung / Manually curated celltypes from each tissue

WASF1 DPPA4

2.04e-03178172c7895ba2e2e93b26da91faa2a3bf9d070dd4c3bd
ToppCell3'_v3-Lung-Hematopoietic_progenitors-HSC-MPP|Lung / Manually curated celltypes from each tissue

WASF1 DPPA4

2.06e-031791722c03b82ec9b4dee2501752b8d83e7028f0aaed77
ToppCellPBMC-Convalescent-Hematopoietic|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

DPPA4 WASF3

2.06e-031791723b1616e974ea7792ff5c37da3b0281f28edfbb56
ToppCellCOVID-19_Convalescent-PLT_1|World / Disease Group and Platelet Clusters

PTPRG CWF19L2

2.06e-03179172d0f2764c6fc5d61fd69e9231b3603a80ac373f65
ToppCellPBMC-Convalescent-Hematopoietic|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DPPA4 WASF3

2.06e-0317917235271a4396a533f6d960ce55d171a32d9d2fd1a4
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

PTPRG FKBP5

2.06e-03179172dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellmild-Myeloid-pDC|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

WASF1 DPPA4

2.08e-0318017238614155fa537d0defda914c531c697be0ef06d8
ToppCellmoderate-Myeloid-pDC|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

WASF1 DPPA4

2.08e-03180172a0751ad5e42a21cb107d900abfa9ee967a0069fc
ToppCellmoderate-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

WASF1 DPPA4

2.08e-031801721d8df7df03a71f49d6683554d3c948ce90dda42e
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

PTPRG FKBP5

2.10e-031811722b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRG SERPINB2

2.10e-03181172ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DPPA4 FKBP5

2.13e-03182172b86690c109cdc16844a6cd2216c1bf2bf28efd45
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|lymph-node_spleen / Manually curated celltypes from each tissue

DPPA4 C16orf96

2.15e-031831726c55fd737ed31f5b1aa41dc4dba7240521c19022
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

TMTC3 WASF1

2.17e-03184172ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellBAL-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WASF1 DPPA4

2.20e-03185172f4588468e8654363f48adbe427dff10f16f1c7fe
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPPA4 FKBP5

2.20e-031851727d6954bb04368ec62b284ba6c3021a15fbdfdee6
ToppCellBAL-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WASF1 DPPA4

2.20e-031851723cb816fc9541c04b4436e21d984216cfbbacff98
ToppCellBAL-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

WASF1 DPPA4

2.20e-03185172c2e70405969616c28fb6379ee318e17bbcef7b49
ToppCellMild-Lymphoid-pDC|Mild / Condition, Lineage, Cell class and cell subclass

WASF1 DPPA4

2.22e-031861727fa82972c726025d6402e5eb7bf0db3b699eba4c
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DPPA4 FKBP5

2.22e-03186172855c2e5a8a6cf94c7de31982e0e2416f924439d3
ToppCellBAL-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

WASF1 DPPA4

2.22e-03186172d2fbf53aac905c9896272ec5c2db28ee1a60f4be
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WASF1 KCNH1

2.22e-03186172bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRG FKBP5

2.22e-03186172db4d9ac89cc1e55062ba888b3410b773340595dd
ToppCellMild-Lymphoid-pDC-|Mild / Condition, Lineage, Cell class and cell subclass

WASF1 DPPA4

2.22e-031861721d05e73ae2ec0cc27f79e4fa40d6b21790059f80
ToppCellBAL-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

WASF1 DPPA4

2.22e-0318617279aedd5aed72509a4925e9f6cb43bc0c798c86f5
ToppCellBAL-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

WASF1 DPPA4

2.22e-03186172b031f4e6867b6200b85f43276a34749bf5f4603f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WASF1 KCNH1

2.24e-03187172f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

FKBP5 WASF3

2.24e-031871724ea486991f66c29728d127171a07b81404ec0b78
ToppCellMild_COVID-19-Myeloid-pDC|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

WASF1 DPPA4

2.24e-0318717299c3c4a7b9179dce7982dc6516d561c952abc80e
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRG FKBP5

2.24e-0318717286250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WASF1 KCNH1

2.27e-0318817250c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic_-_developing-thymocyte|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DPPA4 FKBP5

2.27e-03188172bcfc426b60d8e5a23a2360bfb68b32868fec9fbf
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

GRM5 KCNH1

2.27e-03188172e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCell390C-Lymphocytic-CD4_T-cell|390C / Donor, Lineage, Cell class and subclass (all cells)

PPP1R2 FKBP5

2.27e-031881720da6d6d3c28e9d99159b1a24a345a2250e8e1995
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WASF1 WASF3

2.29e-031891724dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WASF1 WASF3

2.29e-031891720d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WASF1 KCNH1

2.29e-03189172a75226616340045b581d08429d2e123e041dee55
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FKBP5 SERPINB2

2.29e-0318917255aba1ebc012006a5db3ff9c92589cb3d9f7c68a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FKBP5 WASF3

2.29e-03189172c734e5693808a0333139e87bd5be2597a9252afe
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WASF1 KCNH1

2.29e-03189172c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCellSupraBC-Differ-KC|World / shred by cell class for mouse tongue

PPP1R2 SERPINB2

2.29e-031891726412741b88e241304033b41effca0c77a374d907
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R2 PTPRG

2.31e-03190172f98e2d45fab7d9e16629d7f13cc2ccfb939ef4dd
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FKBP5 WASF3

2.31e-03190172445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FKBP5 SPTAN1

2.31e-0319017291ba66d4b56c59523485b17738e93f14bb00afa4
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

FKBP5 WASF3

2.31e-0319017212992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WASF1 KCNH1

2.31e-0319017249e09cdb843b3d889a06a811aa5affae68b25a75
ToppCell(1)_T_cells-(1)_T_CD4_fh|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PPP1R2 FKBP5

2.31e-03190172120ca702600373c208a3d032fede0a040736e5cf
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FKBP5 WASF3

2.31e-031901722e592323085ba9c019d678ac2a784462ab470ed9
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

PTPRG FKBP5

2.31e-031901727f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

GRM5 WASF1

2.31e-031901727dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WASF1 KCNH1

2.31e-03190172d594da827e3c16644952b9589cc12b947ce36279
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

PTPRG FKBP5

2.34e-03191172ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FKBP5 WASF3

2.34e-03191172cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellhematopoetic_progenitors-CD34+_MEP_1|World / Lineage and Cell class

DTD1 DPPA4

2.34e-0319117291327184ca40bfb8c9e904991b1be503aaccd7bc
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R2 PTPRG

2.34e-031911725020fe6c3452e7fab57847f5043d28ebbc5aa381
ToppCellfacs-Heart-LA-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R2 PTPRG

2.34e-03191172827be47d3574c6c5b021c6f1c1670834344f10cb
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R2 PTPRG

2.34e-03191172a15f0fb4bd7dd77ef5f931b6fc9d68697deec1d1
ToppCellwk_20-22-Hematologic_Lymphocytic-B-Late_pre-B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PPP1R2 WASF1

2.34e-031911722b05be1888cccd03a32341bcb1de4a899d4179fd
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

PTPRG FKBP5

2.34e-03191172d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

FKBP5 WASF3

2.34e-0319117270c067c54084bfb02c29bab085f4defd477194fb
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FKBP5 WASF3

2.34e-03191172806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FKBP5 WASF3

2.34e-03191172c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell(1)_T_CD4_fh|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PPP1R2 FKBP5

2.34e-0319117266ddff9a99092cb384b9fb2a3ba95ddbebed67cc
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

FKBP5 WASF3

2.36e-03192172356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellPBMC-Control-cDC_6|Control / Compartment, Disease Groups and Clusters

PPP1R2 SPTY2D1

2.36e-0319217241a7201febb7d88a39e4ee64df04cce18c691df8
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PPP1R2 WASF3

2.36e-03192172d43caf42ec744e895137f31ef65a990e250669d2
ToppCellEndothelial-A|World / shred on cell class and cell subclass (v4)

PPP1R2 PTPRG

2.36e-031921729919cdc0ce833894525dba429f251ea1b094fbd8
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRG FKBP5

2.36e-031921721ccc47792edf9ee23501c8e2165d11271636b66a
Diseasehair color

TMTC3 GRM5 KCNH1

7.07e-04311173EFO_0003924
DiseaseHIV-1 infection

GRM5 SPTY2D1

1.44e-0398172EFO_0000180
DiseaseDupuytren Contracture

PTPRG WASF3

1.74e-03108172EFO_0004229
Diseaseskin pigmentation measurement

TMTC3 GRM5

2.78e-03137172EFO_0007009
Diseaseunipolar depression, bipolar disorder

GRM5 WASF3

3.59e-03156172EFO_0003761, MONDO_0004985
DiseaseEndometriosis

DICER1 FKBP5

3.81e-03161172C0014175
DiseaseEndometrioma

DICER1 FKBP5

3.81e-03161172C0269102
Diseaseepilepsy (implicated_via_orthology)

TMTC3 KCNH1

3.91e-03163172DOID:1826 (implicated_via_orthology)
Diseasehair colour measurement

TMTC3 GRM5 KCNH1

4.93e-03615173EFO_0007822
Diseaselymphocyte percentage of leukocytes

PPP1R2 TMTC3 FKBP5

6.12e-03665173EFO_0007993
DiseaseMajor Depressive Disorder

GRM5 FKBP5

8.47e-03243172C1269683
Diseasephysical activity measurement

GRM5 CWF19L2

8.60e-03245172EFO_0008002

Protein segments in the cluster

PeptideGeneStartEntry
SWTKNEDEKEKTFTK

PTPRG

386

P23470
MEKAKGKEWTSTEKS

DPPA4

11

Q7L190
KSNTDKWEKDEMTKD

DICER1

1391

Q9UPY3
EKAKESWEMDTKEKL

FKBP5

251

Q13451
ELKMDDDEVWSKKSN

GRM5

491

P41594
KKAIMESDEEWSMNK

CWF19L2

786

Q2TBE0
KSEDWNKVSKAESME

KCNH1

846

O95259
VDEELSKKSQKWDEM

PPP1R2

36

P41236
EDESGKHWSKSVMDK

DTD1

56

Q8TEA8
HEDSWKKAMEELSKD

C16orf96

846

A6NNT2
LNKWTSKDKMAEDEV

SERPINB2

291

P05120
MESSWKEQQKEEAKS

SPTY2D1

641

Q68D10
DSDELKSWVNEKMKT

SPTAN1

581

Q13813
WKEKMLQDTEDKRKE

WASF3

161

Q9UPY6
WKEKMLQDTEDKRKE

WASF1

161

Q92558
EKDTMDNWDEKKLEE

ZC3H15

146

Q8WU90
DDKKDNEAEIWMKKA

TMTC3

681

Q6ZXV5