Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	MLL3/4 complex	NCOA6 KDM6A UTY	1.54e-05	12	88	3	GO:0044666
HumanPheno	Positive Romberg sign	FLVCR1 TWNK RFC1 PLS1	2.10e-05	30	29	4	HP:0002403
Domain	Perilipin	PLIN4 PLIN2	2.08e-04	5	86	2	IPR004279
Domain	Perilipin	PLIN4 PLIN2	2.08e-04	5	86	2	PF03036
Domain	-	LILRA3 CD300LD FN1 PTPRK KALRN TSPOAP1 LRFN5 CRLF3 PKHD1 LSAMP SLAMF7	2.26e-04	663	86	11	2.60.40.10
Domain	FN3	FN1 PTPRK KALRN TSPOAP1 LRFN5 CRLF3	3.14e-04	199	86	6	PS50853
Domain	Ig-like_fold	LILRA3 CD300LD FN1 PTPRK KALRN TSPOAP1 LRFN5 CRLF3 PKHD1 LSAMP SLAMF7	3.86e-04	706	86	11	IPR013783
Domain	FN3_dom	FN1 PTPRK KALRN TSPOAP1 LRFN5 CRLF3	4.08e-04	209	86	6	IPR003961
Domain	VWFC_1	FSTL1 MUC2 SSPOP	6.03e-04	36	86	3	PS01208
Domain	VWFC_2	FSTL1 MUC2 SSPOP	7.08e-04	38	86	3	PS50184
Domain	VWF_dom	FSTL1 MUC2 SSPOP	9.50e-04	42	86	3	IPR001007
Domain	TIL	MUC2 SSPOP	1.34e-03	12	86	2	PF01826
Domain	C8	MUC2 SSPOP	1.34e-03	12	86	2	PF08742
Domain	Unchr_dom_Cys-rich	MUC2 SSPOP	1.58e-03	13	86	2	IPR014853
Domain	C8	MUC2 SSPOP	1.58e-03	13	86	2	SM00832
Domain	FN3	FN1 PTPRK KALRN TSPOAP1 CRLF3	1.65e-03	185	86	5	SM00060
Domain	TIL_dom	MUC2 SSPOP	1.84e-03	14	86	2	IPR002919
Domain	TPR_8	TMTC2 KDM6A UTY	1.87e-03	53	86	3	PF13181
Domain	VWD	MUC2 SSPOP	2.41e-03	16	86	2	SM00216
Domain	VWF_type-D	MUC2 SSPOP	2.41e-03	16	86	2	IPR001846
Domain	VWFD	MUC2 SSPOP	2.41e-03	16	86	2	PS51233
Domain	VWD	MUC2 SSPOP	2.41e-03	16	86	2	PF00094
Domain	CTCK_1	MUC2 SSPOP	3.06e-03	18	86	2	PS01185
Domain	IG	LILRA3 CD300LD PTPRK KALRN LRFN5 LSAMP SLAMF7	3.28e-03	421	86	7	SM00409
Domain	Ig_sub	LILRA3 CD300LD PTPRK KALRN LRFN5 LSAMP SLAMF7	3.28e-03	421	86	7	IPR003599
Domain	VWC_out	MUC2 SSPOP	3.41e-03	19	86	2	SM00215
Domain	RhoGEF	KALRN FGD4 AKAP13	3.81e-03	68	86	3	SM00325
Domain	RhoGEF	KALRN FGD4 AKAP13	4.13e-03	70	86	3	PF00621
Domain	DH_2	KALRN FGD4 AKAP13	4.13e-03	70	86	3	PS50010
Domain	DH-domain	KALRN FGD4 AKAP13	4.30e-03	71	86	3	IPR000219
Domain	-	KALRN FGD4 AKAP13	4.30e-03	71	86	3	1.20.900.10
Domain	JmjC	KDM6A UTY	5.42e-03	24	86	2	PF02373
Domain	Cys_knot_C	MUC2 SSPOP	5.87e-03	25	86	2	IPR006207
Domain	CTCK_2	MUC2 SSPOP	5.87e-03	25	86	2	PS01225
Pubmed	Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.	KALRN FGD4 NGFR AKAP13	2.89e-06	38	90	4	11756498
Pubmed	Human transcription factor protein interaction networks.	TRIM33 NCOA6 ZFHX4 ZNF644 ENTR1 BCORL1 ZNF507 TWNK TNIP1 MSL1 TNRC6C RFC1 ANKHD1 KDM6A NPAT	3.77e-06	1429	90	15	35140242
Pubmed	NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.	KALRN FGD4 NGFR AKAP13	4.79e-06	43	90	4	12376548
Pubmed	Cetuximab directly inhibits P-glycoprotein function in vitro independently of EGFR binding.	EGFR ABCB1	6.62e-06	2	90	2	25930120
Pubmed	An H-YDb epitope is encoded by a novel mouse Y chromosome gene.	KDM6A UTY	6.62e-06	2	90	2	8944031
Pubmed	Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function.	PTPRK EGFR	6.62e-06	2	90	2	16263724
Pubmed	Quantitative trait loci linked to thalamus and cortex gray matter volumes in BXD recombinant inbred mice.	FGD4 TNFRSF17	6.62e-06	2	90	2	17406662
Pubmed	Oxidative inhibition of receptor-type protein-tyrosine phosphatase kappa by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes.	PTPRK EGFR	6.62e-06	2	90	2	16849327
Pubmed	Osimertinib (AZD9291), a Mutant-Selective EGFR Inhibitor, Reverses ABCB1-Mediated Drug Resistance in Cancer Cells.	EGFR ABCB1	6.62e-06	2	90	2	27649127
Pubmed	Plakophilin-2 promotes tumor development by enhancing ligand-dependent and -independent epidermal growth factor receptor dimerization and activation.	EGFR PKP2	6.62e-06	2	90	2	25113560
Pubmed	FSTL1 promotes alveolar epithelial cell aging and worsens pulmonary fibrosis by affecting SENP1-mediated DeSUMOylation.	SENP1 FSTL1	6.62e-06	2	90	2	37369969
Pubmed	EGFR mediates docetaxel resistance in human castration-resistant prostate cancer through the Akt-dependent expression of ABCB1 (MDR1).	EGFR ABCB1	6.62e-06	2	90	2	24888374
Pubmed	Calcium-activated chloride channel regulator 1 (CLCA1) forms non-covalent oligomers in colonic mucus and has mucin 2-processing properties.	CLCA1 MUC2	6.62e-06	2	90	2	31570526
Pubmed	Sex-specific differences in expression of histone demethylases Utx and Uty in mouse brain and neurons.	KDM6A UTY	6.62e-06	2	90	2	18434530
Pubmed	PTPRK, an EGFR Phosphatase, Is Decreased in CeD Biopsies and Intestinal Organoids.	PTPRK EGFR	6.62e-06	2	90	2	36611909
Pubmed	Target sequencing and CRISPR/Cas editing reveal simultaneous loss of UTX and UTY in urothelial bladder cancer.	KDM6A UTY	6.62e-06	2	90	2	27533081
Pubmed	Positive and negative selection on mammalian Y chromosomes.	KDM6A UTY	6.62e-06	2	90	2	15758204
Pubmed	Lysine demethylases KDM6A and UTY: The X and Y of histone demethylation.	KDM6A UTY	6.62e-06	2	90	2	31097364
Pubmed	A secreted protein microarray platform for extracellular protein interaction discovery.	CD300LD NGFR LSAMP SLAMF7	9.55e-06	51	90	4	21982860
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	FN1 TLN2 PLS1	1.33e-05	18	90	3	12119179
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZFHX4 ZNF644 BCORL1 ZNF507 TNIP1 ANKHD1 LUZP1 NPAT	1.34e-05	418	90	8	34709266
Pubmed	Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).	KALRN FGD4 NGFR AKAP13	1.83e-05	60	90	4	12787561
Pubmed	Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.	NCOA6 KDM6A UTY	1.85e-05	20	90	3	19047629
Pubmed	S3-12, Adipophilin, and TIP47 package lipid in adipocytes.	PLIN4 PLIN2	1.98e-05	3	90	2	15731108
Pubmed	Epithelial to mesenchymal transition promotes breast cancer progression via a fibronectin-dependent STAT3 signaling pathway.	FN1 EGFR	1.98e-05	3	90	2	23653350
Pubmed	Renal UTX-PHGDH-serine axis regulates metabolic disorders in the kidney and liver.	KDM6A PHGDH	1.98e-05	3	90	2	35788583
Pubmed	Receptor type protein tyrosine phosphatase-kappa mediates cross-talk between transforming growth factor-beta and epidermal growth factor receptor signaling pathways in human keratinocytes.	PTPRK EGFR	1.98e-05	3	90	2	19864455
Pubmed	Transforming growth factor {beta} (TGF-{beta})-Smad target gene protein tyrosine phosphatase receptor type kappa is required for TGF-{beta} function.	PTPRK EGFR	1.98e-05	3	90	2	15899872
Pubmed	The UTX gene escapes X inactivation in mice and humans.	KDM6A UTY	1.98e-05	3	90	2	9499428
Pubmed	Population Pharmacokinetics, Pharmacogenomics, and Adverse Events of Osimertinib and its Two Active Metabolites, AZ5104 and AZ7550, in Japanese Patients with Advanced Non-small Cell Lung Cancer: a Prospective Observational Study.	EGFR ABCB1	1.98e-05	3	90	2	36637703
Pubmed	EGFR transcriptionally upregulates UTX via STAT3 in non-small cell lung cancer.	EGFR KDM6A	1.98e-05	3	90	2	34661759
Pubmed	Concomitance of P-gp/LRP Expression with EGFR Mutations in Exons 19 and 21 in Non-Small Cell Lung Cancers.	EGFR ABCB1	1.98e-05	3	90	2	26632382
Pubmed	Pharmacogenetics of ABCG2 and adverse reactions to gefitinib.	EGFR ABCB1	1.98e-05	3	90	2	17148776
Pubmed	Activation of epidermal growth factor receptor gene is involved in transforming growth factor-beta-mediated fibronectin expression in a chondrocyte progenitor cell line.	FN1 EGFR	1.98e-05	3	90	2	20198308
Pubmed	SLAMF7 regulates the inflammatory response in macrophages during polymicrobial sepsis.	INPP5D SLAMF7	1.98e-05	3	90	2	36749634
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	TRIM33 SH3RF1 ZNF644 ENTR1 BCORL1 ZNF507 TNIP1 CGNL1 LUZP1	2.22e-05	588	90	9	38580884
Pubmed	Immune cell inhibition by SLAMF7 is mediated by a mechanism requiring src kinases, CD45, and SHIP-1 that is defective in multiple myeloma cells.	INPP5D SLAMF7	3.96e-05	4	90	2	25312647
Pubmed	Perilipin family (PLIN) proteins in human skeletal muscle: the effect of sex, obesity, and endurance training.	PLIN4 PLIN2	3.96e-05	4	90	2	22667335
Pubmed	Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30.	FN1 EGFR	3.96e-05	4	90	2	19342448
Pubmed	[Differential expressions of MDR-1, RRM-1, EGFR and ERCC-1 in primary tumors and metastatic lymph nodes of NSCLC patients].	EGFR ABCB1	3.96e-05	4	90	2	23948418
Pubmed	Groucho/transducin-like enhancer of split (TLE) family members interact with the yeast transcriptional co-repressor SSN6 and mammalian SSN6-related proteins: implications for evolutionary conservation of transcription repression mechanisms.	KDM6A UTY	3.96e-05	4	90	2	9854018
Pubmed	X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.	KDM6A UTY	3.96e-05	4	90	2	32732223
Pubmed	Deletion and expression analysis of AZFa genes on the human Y chromosome revealed a major role for DBY in male infertility.	KDM6A UTY	3.96e-05	4	90	2	10767340
Pubmed	Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance.	PLIN4 PLIN2	6.59e-05	5	90	2	18487449
Pubmed	Ethnicity-Based Variations in Focal Adhesion Kinase Signaling in Glioblastoma Gene Expression: A Study of the Puerto Rican Hispanic Population.	EGFR NGFR	6.59e-05	5	90	2	38732165
Pubmed	Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins.	PLIN4 PLIN2	6.59e-05	5	90	2	19638644
Pubmed	Perilipin family members preferentially sequester to either triacylglycerol-specific or cholesteryl-ester-specific intracellular lipid storage droplets.	PLIN4 PLIN2	6.59e-05	5	90	2	22685330
Pubmed	Bile acid regulates MUC2 transcription in colon cancer cells via positive EGFR/PKC/Ras/ERK/CREB, PI3K/Akt/IkappaB/NF-kappaB and p38/MSK1/CREB pathways and negative JNK/c-Jun/AP-1 pathway.	EGFR MUC2	6.59e-05	5	90	2	20198339
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	TCTN3 TTBK2 PUS10 CNTRL SPATA22 ANKHD1 IFI16 GRHL2 KDM6A	7.31e-05	686	90	9	29987050
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	TRIM33 RC3H2 AARS1 ZFHX4 BCORL1 KDM6A PLS1	8.06e-05	398	90	7	35016035
Pubmed	Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly.	PCSK2 CNTRL	9.87e-05	6	90	2	15337773
Pubmed	Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins.	ENTR1 TNIP1 ANKHD1	1.03e-04	35	90	3	27812135
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TRIM33 NCOA6 AARS1 INPP5D ZNF644 BCORL1 ZNF507 RFC1 IFI16 KDM6A PHGDH	1.31e-04	1103	90	11	34189442
Pubmed	UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling.	KDM6A UTY	1.38e-04	7	90	2	29551674
Pubmed	Area identity shifts in the early cerebral cortex of Emx2-/- mutant mice.	NGFR LSAMP	1.38e-04	7	90	2	10862700
Pubmed	Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.	NCOA6 KDM6A	1.84e-04	8	90	2	17178841
Pubmed	Beta1 integrins are required for the invasion of the caecum and proximal hindgut by enteric neural crest cells.	FN1 NGFR	1.84e-04	8	90	2	19633172
Pubmed	Chromosomal location of the murine anion exchanger genes encoding AE2 and AE3.	FN1 ABCB1	1.84e-04	8	90	2	7894173
Pubmed	UTX deficiency in neural stem/progenitor cells results in impaired neural development, fetal ventriculomegaly, and postnatal death.	KDM6A UTY	1.84e-04	8	90	2	36412518
Pubmed	TWE-PRIL reverse signalling suppresses sympathetic axon growth and tissue innervation.	NGFR TNFRSF17	1.84e-04	8	90	2	30337376
Pubmed	Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL.	CLCA1 FN1	1.84e-04	8	90	2	27010197
Pubmed	ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking.	EGFR INPP5D	2.36e-04	9	90	2	21275903
Pubmed	UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development.	KDM6A UTY	2.36e-04	9	90	2	23028370
Pubmed	Alpha-Catulin, a New Player in a Rho Dependent Apical Constriction That Contributes to the Mouse Neural Tube Closure.	FN1 NGFR	2.36e-04	9	90	2	32258033
Pubmed	UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity.	KDM6A UTY	2.36e-04	9	90	2	22949634
Pubmed	Expression of mRNA and protein-protein interaction of the antiviral endoribonuclease RNase L in mouse spleen.	AARS1 FN1	2.36e-04	9	90	2	24780566
Pubmed	The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity.	FN1 GRHL2	2.36e-04	9	90	2	21081122
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	SH3RF1 DCTN5 KALRN TNRC6C LUZP1	2.64e-04	218	90	5	33378226
Pubmed	Identification of two clusters of mouse insulin-like growth factor binding protein genes on chromosomes 1 and 11.	FN1 EGFR	2.94e-04	10	90	2	7525452
Pubmed	Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.	NCOA6 KDM6A UTY	3.01e-04	50	90	3	37974198
Pubmed	Interaction network of human early embryonic transcription factors.	TRIM33 NCOA6 ZFHX4 ZNF644 BCORL1 KDM6A	3.09e-04	351	90	6	38297188
Pubmed	Evaluation of candidate markers for the peritubular myoid cell lineage in the developing mouse testis.	FN1 NGFR	3.59e-04	11	90	2	16183868
Pubmed	Co-expression of Tbx6 and Sox2 identifies a novel transient neuromesoderm progenitor cell state.	FN1 NGFR	3.59e-04	11	90	2	29084802
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	NCOA6 SENP1 CGNL1 RFC1 UTY	3.65e-04	234	90	5	36243803
Pubmed	Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes.	MSL1 KDM6A	4.30e-04	12	90	2	23210685
Pubmed	The expression and function of fatty acid transport protein-2 and -4 in the murine placenta.	PLIN4 PLIN2	4.30e-04	12	90	2	22028793
Pubmed	Noses and neurons: induction, morphogenesis, and neuronal differentiation in the peripheral olfactory pathway.	FN1 NGFR	4.30e-04	12	90	2	16193510
Pubmed	Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.	KDM6A UTY	5.07e-04	13	90	2	14660691
Pubmed	UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program.	KDM6A UTY	5.07e-04	13	90	2	22192413
Pubmed	Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.	NCOA6 KDM6A	5.07e-04	13	90	2	17761849
Pubmed	Pharmacogenomic variations in treatment protocols for childhood acute lymphoblastic leukemia.	RFC1 ABCB1	5.07e-04	13	90	2	19774638
Pubmed	Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.	EGFR ENTR1 TNIP1	5.15e-04	60	90	3	34761192
Pubmed	Ligand-activated peroxisome proliferator activated receptor gamma alters placental morphology and placental fatty acid uptake in mice.	PLIN4 PLIN2	5.91e-04	14	90	2	17463056
Pubmed	Polymorphisms in the BRCA1 and ABCB1 genes modulate menopausal hormone therapy associated breast cancer risk in postmenopausal women.	EGFR ABCB1	5.91e-04	14	90	2	19672706
Pubmed	Loss of Gli3 and Shh function disrupts olfactory axon trajectories.	FN1 NGFR	5.91e-04	14	90	2	15065125
Pubmed	Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality.	FN1 TLN2	5.91e-04	14	90	2	19652092
Pubmed	Signal peptide prediction based on analysis of experimentally verified cleavage sites.	LILRA3 FSTL1 EGFR CD177 SLAMF7	6.31e-04	264	90	5	15340161
Pubmed	SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.	ZNF644 PKP2 RFC1 PHGDH	6.37e-04	150	90	4	30154076
Pubmed	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	AKAP13 MUC2	6.80e-04	15	90	2	23583980
Pubmed	Mitochondrial DNA Maintenance Defects Overview	DGUOK TWNK	6.80e-04	15	90	2	29517884
Pubmed	The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex.	NCOA6 KDM6A	6.80e-04	15	90	2	17925232
Pubmed	ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.	ADAMTS10 FN1	6.80e-04	15	90	2	38871984
Pubmed	A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain.	EGFR PLIN2	6.80e-04	15	90	2	38942786
Pubmed	Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes.	FN1 PTPRK LSAMP	7.76e-04	69	90	3	15142957
Pubmed	Loss of alpha3beta1 integrin function results in an altered differentiation program in the mouse submandibular gland.	FN1 TLN2	7.76e-04	16	90	2	11307167
Pubmed	KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis.	KDM6A UTY	7.76e-04	16	90	2	35212626
Pubmed	Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation.	FN1 NGFR	7.76e-04	16	90	2	21067603
Pubmed	H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.	NCOA6 KDM6A	7.76e-04	16	90	2	24368734
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	TRIM33 NCOA6 ZNF644 BCORL1 MSL1 SPATA22 RFC1 LUZP1 NPAT	8.22e-04	954	90	9	36373674
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	PTPRK KALRN LRFN5 LSAMP	8.49e-04	162	90	4	25826454
Cytoband	12p11.21	FGD4 OVOS2	8.56e-04	22	90	2	12p11.21
Cytoband	2p13	OTX1 DGUOK	9.36e-04	23	90	2	2p13
GeneFamily	Fibronectin type III domain containing	FN1 PTPRK KALRN TSPOAP1 LRFN5 CRLF3	1.62e-05	160	61	6	555
GeneFamily	Perilipins	PLIN4 PLIN2	1.11e-04	5	61	2	678
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	LILRA3 CD177 LAMP3 NGFR SLAMF7 TNFRSF17 ABCB1	3.51e-04	394	61	7	471
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	KALRN FGD4 AKAP13	1.44e-03	66	61	3	722
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM6A UTY	2.95e-03	24	61	2	485
GeneFamily	CD molecules\|Tumor necrosis factor receptor superfamily\|Death inducing signaling complex	NGFR TNFRSF17	4.29e-03	29	61	2	782
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500	SPTLC3 TTBK2 ZIK1 CLCA1 ZFHX4 EGFR LSAMP INSYN2B IFI16 UTY	1.02e-05	429	87	10	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	SPTLC3 CLCA1 FSTL1 ZFHX4 EGFR KALRN ENTR1 TLN2 AKAP13 MSL1 TNRC6C IFI16 GRHL2	2.36e-05	806	87	13	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_1000	SPTLC3 TTBK2 ZIK1 CLCA1 ZFHX4 EGFR FLVCR1 AK4 LSAMP TMTC2 INSYN2B IFI16 KDM6A	4.09e-05	850	87	13	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#4_top-relative-expression-ranked_500	TTBK2 ZIK1 ZFHX4 EGFR LSAMP IFI16 UTY	7.01e-05	247	87	7	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#5_top-relative-expression-ranked_1000	SPTLC3 CLCA1 EGFR AKAP13 GRHL2	8.23e-05	108	87	5	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k5
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPTLC3 SH3RF1 PTPRK EGFR FGD4 LAMP3 TMTC2 CGNL1 GRHL2	2.80e-10	199	90	9	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPTLC3 SH3RF1 PTPRK EGFR FGD4 LAMP3 TMTC2 CGNL1 GRHL2	2.80e-10	199	90	9	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SH3RF1 PTPRK EGFR FGD4 LAMP3 TMTC2 CGNL1 GRHL2	7.23e-09	199	90	8	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	SH3RF1 PTPRK EGFR LAMP3 TMTC2 CGNL1 GRHL2	1.28e-07	192	90	7	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SH3RF1 PTPRK EGFR LAMP3 TMTC2 CGNL1 GRHL2	1.42e-07	195	90	7	9406866f99555198a9be311fbd65751b70f35446
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SH3RF1 PTPRK EGFR FGD4 LAMP3 CGNL1 GRHL2	1.63e-07	199	90	7	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PLIN4 PTPRK LAMP3 CGNL1 GRHL2 PLS1	9.63e-07	162	90	6	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTBK2 TNIP1 SLAMF7 KLRG1 PHGDH ABCB1	9.98e-07	163	90	6	a24db9d266a40f3bffe4f18d277bc269791b4560
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD177 FLVCR1 TWNK DCLRE1A SLAMF7 NPAT	1.07e-06	165	90	6	1d0f60bf47a40ac916f0fcb5532a968742a0edbb
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TSPOAP1 BSPRY LAMP3 PKP2 TWNK SLAMF7	1.11e-06	166	90	6	c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	SH3RF1 PTPRK EGFR PKHD1 CGNL1 GRHL2	2.51e-06	191	90	6	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SH3RF1 PTPRK EGFR LAMP3 CGNL1 GRHL2	2.51e-06	191	90	6	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	SH3RF1 PTPRK EGFR LAMP3 CGNL1 GRHL2	2.58e-06	192	90	6	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	PCW_05-06-Epithelial-Epithelial_airway\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FGD4 BSPRY PKHD1 GRHL2 WDR49 PLS1	2.66e-06	193	90	6	af6ec2c2ba92aef3e41531c3c7215b3300437bd9
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SH3RF1 PTPRK FGD4 PKHD1 LAMP3 GRHL2	2.66e-06	193	90	6	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SH3RF1 PTPRK EGFR LAMP3 TMTC2 CGNL1	2.74e-06	194	90	6	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	Control-Epithelial\|Control / Disease state, Lineage and Cell class	SH3RF1 PTPRK EGFR LAMP3 CGNL1 GRHL2	2.82e-06	195	90	6	1798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FSTL1 FN1 ZFHX4 LRFN5 NGFR CGNL1	3.08e-06	198	90	6	9541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	SH3RF1 PTPRK EGFR FGD4 TMTC2 KDM6A	3.08e-06	198	90	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SH3RF1 PTPRK FGD4 TMTC2 CGNL1 GRHL2	3.27e-06	200	90	6	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD177 INPP5D FLVCR1 NGFR SLAMF7	1.68e-05	157	90	5	d8e283414a770f05d71f0455d0822e9a9660b115
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD177 INPP5D FLVCR1 NGFR SLAMF7	1.68e-05	157	90	5	165e98bf944572cafbc06ef43c9eab7bd6bea1c2
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	INPP5D ZNF644 ZNF507 AKAP13 NHLRC2	1.95e-05	162	90	5	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	droplet-Bladder-nan-3m-Hematologic-macrophage\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD300LD INPP5D NRROS SLAMF7 TNFRSF17	1.95e-05	162	90	5	0cee9ef405765f3f82d0cd7b8adc88f6e9fdbb5c
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SPTLC3 ZFHX4 NGFR CGNL1 SSPOP	2.01e-05	163	90	5	961c3a1303108afd680365466045f3460a30a7b0
ToppCell	Basal_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	IGLV3-9 NCOA6 OTX1 CD177 NGFR	2.07e-05	164	90	5	b15a26130a1ea1b370b6e3be21f02a0d6aaf6b3c
ToppCell	droplet-Fat-Gat\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD300LD CD177 TSPOAP1 NGFR PLIN2	2.07e-05	164	90	5	c7ad946829c655038b33748dddd7d68c15489034
ToppCell	droplet-Fat-Gat-18m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD300LD CD177 TSPOAP1 NGFR PLIN2	2.07e-05	164	90	5	3aae702a23fbf1d36a6f18596c23e985581de815
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PLIN4 PTPRK CGNL1 GRHL2 PLS1	2.20e-05	166	90	5	89e2b8453180983533faccb4275867861876d7ee
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	BCORL1 LAMP3 KDM6A LUZP1 PLIN2	2.33e-05	168	90	5	3fb79aaa858057c82645a90bd139fc4f096323c7
ToppCell	facs-Marrow-KLS-3m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRBD1 SLAMF7 TNFRSF17 SSPOP PLS1	2.39e-05	169	90	5	b798b91567d2f49082e2d8a337169f241c8d2080
ToppCell	facs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD300LD INPP5D NRROS SLAMF7 PLIN2	2.46e-05	170	90	5	e4856e768d0088e42fbdb8e6039f5bc3daa0afdb
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF7 TNFRSF17 PLS1 PHGDH ABCB1	2.75e-05	174	90	5	3f4277763e312b46ebd4401ea4a2f5d4c850c768
ToppCell	droplet-Lung-nan-21m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF7 TNFRSF17 PLS1 PHGDH ABCB1	2.75e-05	174	90	5	fad66d1a8407574b6a835e0bdb824a53afa58650
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLAMF7 TNFRSF17 PLS1 PHGDH ABCB1	2.83e-05	175	90	5	28b29f844fa46fe579ddc19039fb2d9dc5f48f3b
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-plasma_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLAMF7 TNFRSF17 PLS1 PHGDH ABCB1	2.83e-05	175	90	5	ac96ca9ca309b0d72a2f5af6a3b02c7f80755750
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF7 TNFRSF17 PLS1 PHGDH ABCB1	2.91e-05	176	90	5	606704098bfdf8bfef740a3544a372fae1e75969
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF7 TNFRSF17 PLS1 PHGDH ABCB1	2.91e-05	176	90	5	acb9e29773030f6452a069f8f7e53eab68ab7bd3
ToppCell	droplet-Spleen-SPLEEN-1m-Lymphocytic-plasma_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FSTL1 PKP2 TNFRSF17 SSPOP ABCB1	3.07e-05	178	90	5	b902059c3f861108fc64cbdc05e6f44378f5be2c
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SH3RF1 PTPRK EGFR CGNL1 PLS1	3.15e-05	179	90	5	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SH3RF1 FGD4 TMTC2 GRHL2 ABCB1	3.32e-05	181	90	5	aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell	COPD-Epithelial-Basal\|World / Disease state, Lineage and Cell class	SH3RF1 PTPRK EGFR NGFR GRHL2	3.32e-05	181	90	5	6d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPRK EGFR LAMP3 CGNL1 GRHL2	3.50e-05	183	90	5	6847c1252d6bb105524f812658112517fd351eab
ToppCell	COPD-Epithelial-Basal\|COPD / Disease state, Lineage and Cell class	SH3RF1 PTPRK EGFR NGFR GRHL2	3.50e-05	183	90	5	0f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 KALRN PKHD1 TLN2 SSPOP	3.59e-05	184	90	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	PCSK2 PTPRK EGFR LAMP3 GRHL2	3.59e-05	184	90	5	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 KALRN PKHD1 TLN2 SSPOP	3.59e-05	184	90	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 KALRN PKHD1 TLN2 SSPOP	3.59e-05	184	90	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TSPOAP1 FGD4 BSPRY PKHD1 PLS1	3.69e-05	185	90	5	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FGD4 PKHD1 LAMP3 GRHL2 PLS1	3.78e-05	186	90	5	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FGD4 PKHD1 AK4 CGNL1 PLIN2	3.88e-05	187	90	5	3ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PTPRK EGFR LAMP3 CGNL1 GRHL2	3.98e-05	188	90	5	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FGD4 PKHD1 GRHL2 WDR49 PLS1	4.08e-05	189	90	5	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	BSPRY PKHD1 GRHL2 WDR49 PLS1	4.08e-05	189	90	5	c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FSTL1 EGFR KALRN LRFN5 IFI16	4.19e-05	190	90	5	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FSTL1 EGFR KALRN LRFN5 IFI16	4.19e-05	190	90	5	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FGD4 BSPRY PKHD1 GRHL2 PLS1	4.29e-05	191	90	5	72dbd2e0fabfca8d6f604df35277d3574739a0b3
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PTPRK FGD4 PKHD1 LAMP3 GRHL2	4.29e-05	191	90	5	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TSPOAP1 INPP5D SLAMF7 IFI16 ABCB1	4.29e-05	191	90	5	9b8b64a36e27a2523b8730c7922fd7ad865a021e
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TSPOAP1 INPP5D SLAMF7 KLRG1 ABCB1	4.29e-05	191	90	5	6345c1aa0fd2f9f2154a44f9393bf7c72bb1f44e
ToppCell	Control-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	SH3RF1 PTPRK EGFR LAMP3 CGNL1	4.40e-05	192	90	5	1bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	FSTL1 PTPRK EGFR DCLRE1A PLS1	4.40e-05	192	90	5	8899d81306770adda893b5e146df1253971754c5
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	BSPRY PKHD1 LAMP3 GRHL2 PLS1	4.40e-05	192	90	5	39804d9ddc67c1b41887752df2503389eae44a1a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PTPRK PKHD1 AKAP13 CGNL1 GRHL2	4.40e-05	192	90	5	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	FSTL1 PTPRK EGFR DCLRE1A PLS1	4.40e-05	192	90	5	5fda9a465c9f77c7fa1a3ea07a2b0374bbc23b2a
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FGD4 BSPRY PKHD1 GRHL2 PLS1	4.40e-05	192	90	5	d3634574b2e8d2ded6446969361b70761b331aea
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FGD4 BSPRY PKHD1 GRHL2 PLS1	4.40e-05	192	90	5	b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FGD4 PKHD1 CGNL1 GRHL2 WDR49	4.40e-05	192	90	5	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PTPRK FGD4 PKHD1 LAMP3 GRHL2	4.40e-05	192	90	5	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FGD4 BSPRY PKHD1 GRHL2 PLS1	4.40e-05	192	90	5	1aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SH3RF1 PTPRK FGD4 PKHD1 AKAP13	4.40e-05	192	90	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FGD4 LSAMP AKAP13 ANKHD1 KDM6A	4.51e-05	193	90	5	779276e775cb2492e8dd36436295a536084a6415
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SH3RF1 FGD4 PKHD1 AKAP13 GRHL2	4.62e-05	194	90	5	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SH3RF1 FGD4 PKHD1 AKAP13 GRHL2	4.62e-05	194	90	5	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FGD4 BSPRY PKHD1 LAMP3 GRHL2	4.62e-05	194	90	5	413112ee8df7407fd418d57c2ff11aad3a6ec259
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SH3RF1 PTPRK FGD4 PKHD1 CGNL1	4.62e-05	194	90	5	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FGD4 BSPRY PKHD1 GRHL2 PLS1	4.62e-05	194	90	5	acd5ba9a097595d4caab4f05440531c65a4aa7bc
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SH3RF1 FGD4 PKHD1 CGNL1 GRHL2	4.62e-05	194	90	5	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FSTL1 ZFHX4 KALRN LRFN5 LSAMP	4.62e-05	194	90	5	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	PCW_05-06-Epithelial\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FGD4 BSPRY PKHD1 GRHL2 PLS1	4.62e-05	194	90	5	47a1369c22fcbfe00b08376eb610a61c355548db
ToppCell	Control-Multiplet\|Control / Disease state, Lineage and Cell class	SH3RF1 PTPRK EGFR LAMP3 GRHL2	4.74e-05	195	90	5	618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SH3RF1 FGD4 PKHD1 CGNL1 GRHL2	4.74e-05	195	90	5	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	Control-Multiplet-Multiplet\|Control / Disease state, Lineage and Cell class	SH3RF1 PTPRK EGFR LAMP3 GRHL2	4.74e-05	195	90	5	06ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCSK2 SPTLC3 LAMP3 AKAP13 CGNL1	4.85e-05	196	90	5	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FSTL1 FN1 LSAMP TMTC2 PHGDH	4.85e-05	196	90	5	cbfe01ba8071864e19b37028236ae35789f630fe
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	BSPRY PKHD1 LAMP3 GRHL2 PLS1	4.85e-05	196	90	5	0a34a0009f479384f1994c6f977f942699a132c8
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FSTL1 FN1 LRFN5 TLN2 LSAMP	4.85e-05	196	90	5	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	RA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	SH3RF1 FN1 LRFN5 TMTC2 PLIN2	4.85e-05	196	90	5	e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FSTL1 FN1 EGFR KALRN LRFN5	4.97e-05	197	90	5	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FSTL1 FN1 EGFR KALRN LRFN5	4.97e-05	197	90	5	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FSTL1 FN1 EGFR KALRN LRFN5	4.97e-05	197	90	5	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FN1 LRFN5 LSAMP TMTC2 SPATA22	4.97e-05	197	90	5	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	distal-3-Endothelial-Bronchial_Vessel_2\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TTBK2 AARS1 INPP5D AK4 DCLRE1A	5.09e-05	198	90	5	f701d06e3d7fd2192afae3698c5ec3c355e96da3
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-B_(AT2)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	PCSK2 LAMP3 AKAP13 PHGDH PLIN2	5.09e-05	198	90	5	391f59e232269f6ae9f8792d21a60ad534e03c4d
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FSTL1 FN1 KALRN LRFN5 LSAMP	5.09e-05	198	90	5	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FGD4 INPP5D TLN2 AKAP13 LUZP1	5.22e-05	199	90	5	b0a906586e58009f5ed9272fc29ba28e49c85ee6
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	INPP5D SLAMF7 IFI16 KLRG1 ABCB1	5.34e-05	200	90	5	7a9c3f51d4a8fda5f1b7e0be6fcf9c1c92fffe99
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	INPP5D SLAMF7 IFI16 KLRG1 ABCB1	5.34e-05	200	90	5	66fb892bda1d29e67a65717e85f2ec221f520b2a
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Chrna6\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	OTX1 FN1 TMTC2 PLS1	1.21e-04	125	90	4	fac8a9bff83abb8976013ff7d2b4ce0b68fbb70a
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PLIN4 SSPOP PLS1 CHRNE	1.49e-04	132	90	4	dc6edfa821a1cdc645668b0af5ba5ff80dee10bd
Disease	Kabuki syndrome (implicated_via_orthology)	KDM6A UTY	2.40e-05	3	84	2	DOID:0060473 (implicated_via_orthology)
Disease	Mitochondrial DNA depletion syndrome 15 (hepatocerebral type)	DGUOK TWNK	4.79e-05	4	84	2	cv:C4310690
Disease	Rectal Carcinoma	EGFR MUC2	1.67e-04	7	84	2	C0007113
Disease	Rectal Neoplasms	EGFR MUC2	1.67e-04	7	84	2	C0034885
Disease	Colorectal Carcinoma	PCSK2 FN1 EGFR KALRN PUS10 PKHD1 KDM6A WDR49 ABCB1	1.74e-04	702	84	9	C0009402
Disease	alcohol use disorder (implicated_via_orthology)	PCSK2 EGFR KDM6A UTY CHRNE	2.42e-04	195	84	5	DOID:1574 (implicated_via_orthology)
Disease	Mitochondrial DNA Deletion Syndromes	DGUOK TWNK	2.85e-04	9	84	2	cv:CN043632
Disease	Autosomal Recessive Polycystic Kidney Disease	EGFR PKHD1	2.85e-04	9	84	2	C0085548
Disease	platelet glycoprotein ib alpha chain measurement	AK4 CHRNE	3.55e-04	10	84	2	EFO_0020645
Disease	Aortic Valve Insufficiency	FSTL1 FN1	4.33e-04	11	84	2	C0003504
Disease	renal cell carcinoma (is_marker_for)	FN1 EGFR KDM6A ABCB1	4.98e-04	128	84	4	DOID:4450 (is_marker_for)
Disease	bipolar disorder, response to lithium ion	EGFR LAMP3	7.13e-04	14	84	2	GO_0010226, MONDO_0004985
Disease	red blood cell density measurement	TRIM33 KALRN FLVCR1 PKHD1 AKAP13 CGNL1 RFC1 PLS1 PHGDH	8.94e-04	880	84	9	EFO_0007978
Disease	cutaneous Leishmaniasis	CRLF3 LAMP3	9.36e-04	16	84	2	EFO_0005046
Disease	Malignant neoplasm of breast	NCOA6 FN1 EGFR KALRN ZNF644 BCORL1 TNIP1 PHGDH ABCB1 WDR53	9.42e-04	1074	84	10	C0006142
Disease	Adrenocortical carcinoma	EGFR ABCB1	1.19e-03	18	84	2	C0206686
Disease	sphingomyelin measurement	SPTLC3 SENP1 TNRC6C KLRG1 CHRNE	1.21e-03	278	84	5	EFO_0010118
Disease	Systemic Scleroderma	FSTL1 TNIP1	1.33e-03	19	84	2	C0036421
Disease	Esophageal Neoplasms	EGFR AKAP13 ABCB1	1.45e-03	78	84	3	C0014859
Disease	Malignant neoplasm of esophagus	EGFR AKAP13 ABCB1	1.45e-03	78	84	3	C0546837
Disease	multiple sclerosis	PTPRK TSPOAP1 PUS10 AKAP13 NRROS SLAMF7 PHGDH	1.54e-03	594	84	7	MONDO_0005301
Disease	pulse pressure measurement	RC3H2 SENP1 FN1 ZFHX4 CNTRL TLN2 AKAP13 DCLRE1A SSPOP LUZP1 PLIN2	1.95e-03	1392	84	11	EFO_0005763
Disease	Charcot-Marie-Tooth disease (implicated_via_orthology)	AARS1 FGD4	2.12e-03	24	84	2	DOID:10595 (implicated_via_orthology)
Disease	periodontal measurement	PKP2 IFI16	2.12e-03	24	84	2	EFO_0007780
Disease	low density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram	CGNL1 GRHL2	2.12e-03	24	84	2	EFO_0004611, EFO_0006329, EFO_0007871
Disease	Deafness	TMTC2 PLS1	2.30e-03	25	84	2	C0011053
Disease	Alzheimer disease	EGFR INPP5D PKHD1 TLN2 TNIP1 CHRNE	2.64e-03	485	84	6	MONDO_0004975

Protein segments in the cluster

Peptide	Gene	Start	Entry
GTIKGQATQAQNECR	CNTRL	626	Q7Z7A1
TVNGSEQGSLTVQCA	CD300LD	26	Q6UXZ3
QRTTQAAGGNVTSCL	BCORL1	666	Q5H9F3
NTQSQGKTSACEVSG	AKAP13	1071	Q12802
AGTQKACTAQSLGNL	DGUOK	81	Q16854
GTKGCSTVGAQNSQK	CD177	261	Q8N6Q3
KCSAQCAGGSQVQAV	ADAMTS10	836	Q9H324
AQAGGQKCTVSINVL	CHRNE	266	Q04844
NKVGVNNTVTTTAGN	RC3H2	461	Q9HBD1
GSRTCSFQKQVAGNS	TSPOAP1	1276	O95153
SQTNGAQIQGCSVTL	LRFN5	571	Q96NI6
QTVALVGNSGCGKST	ABCB1	421	P08183
QGTSSNNKNVLSVGT	NPAT	1211	Q14207
CDNVGSVENGKTNSV	MAP10	256	Q9P2G4
KTNSVVTCSGAGNGR	MAP10	266	Q9P2G4
SGKGTVCQRIAQNFG	AK4	16	P27144
GKANNNVGTGTCDKV	KDM6A	786	O15550
NSASAIGCTVVNIGA	PLS1	201	Q14651
NNTKGQCGTCTNTTS	MUC2	4616	Q02817
AVCISTNGAVFVNGK	CRLF3	351	Q8IUI8
GNDTDKTQGAQTCVA	FGD4	76	Q96M96
ASKQNDLGGCNGTSS	KALRN	2311	O60229
NATQASGNCGTRKSN	LAMP3	266	Q9UQV4
KKGATTQNSEICSGQ	TWNK	656	Q96RR1
SSQQKTSGCFKNDGQ	OVOS2	1056	Q6IE36
GGSGASSQAACLKQI	MSL1	211	Q68DK7
TKNCTTLAGTGDTNN	NHLRC2	506	Q8NBF2
AKCRQQQQSGSGTKS	OTX1	91	P32242
DSVVVNSGKQSNSGA	NCOA6	1306	Q14686
VGSTASKNSNLNVCN	PUS10	96	Q3MIT2
ISNRGENSCKATGQV	EGFR	491	P00533
KGKGQASQTQCNSSS	GRHL2	436	Q6ISB3
SNSFVQTCGAINKNG	KLRG1	156	Q96E93
QTCGAINKNGLQASS	KLRG1	161	Q96E93
NVQNSCAYKVGVASG	BSPRY	291	Q5W0U4
AQGNNQACNSTSEVK	CGNL1	596	Q0VF96
CGQGASLTVVKQNAD	ENTR1	371	Q96C92
LGNGVSCQETAVTQT	FN1	336	P02751
TCDGKNQKGAQTQTE	FSTL1	266	Q12841
TACATAVLGNQLGTA	FLVCR1	236	Q9Y5Y0
TASGNKVSRQSVLCG	DCTN5	16	Q9BTE1
QVTQAANSGCSKAIG	LUZP1	551	Q86V48
NQLCSQTKGSFVNGV	IFI16	676	Q16666
GFNCTTSQGKVALGS	MAN2A2	1091	P49641
VASSQNSSCGDGIQQ	DCLRE1A	76	Q6PJP8
AVCKNVNAGGQSGSL	CCDC168	6651	Q8NDH2
NRSGTATAASQGVCK	NRROS	21	Q86YC3
TSGGNVTIQCDSQVA	LILRA3	136	Q8N6C8
TARITCGGNNIGSKN	IGLV3-9	36	A0A075B6K5
VNAGQNATFQCIATG	PTPRK	206	Q15262
GTKNTVCSGVTGAVN	PLIN4	351	Q96Q06
GVTSAVNVAKGAAQT	PLIN4	656	Q96Q06
NGNVGTGTCDKVNNI	UTY	736	O14607
NESCKQSGLSSLVNG	TRIM33	846	Q9UPN9
CAATQASNSGGKNDG	TNRC6C	481	Q9HCJ0
QCQLQAGSANASAGS	SSPOP	121	A2VEC9
DGKNSCPVSSGAQQQ	SPATA22	141	Q8NHS9
GNYTCVAANKLGVTN	LSAMP	286	Q13449
KTIIGQQGDQSCANK	RFC1	596	P35251
NTGVACPASQNKVQA	SPATA31A6	516	Q5VVP1
KNGNSCASQIIGSDT	SENP1	236	Q9P0U3
CTDNVKTGIANTLGN	INPP5D	506	Q92835
CSQGQGGFTVKTSQL	PKHD1	2491	P08F94
SNGSQSRNCTKNGIV	SPTLC3	21	Q9NUV7
LNFNCSTVVIGNGTA	SRBD1	586	Q8N5C6
NCSSKDLQSSQGGQQ	SH3RF1	106	Q7Z6J0
CNSESSSGGKSQELN	ANKHD1	1601	Q8IWZ3
NTISGCFNEVKQSGA	CLCA1	416	A8K7I4
AVAGQQQASVTAGKV	TNIP1	276	Q15025
RQENGQSTSKLCGTT	ZFHX4	11	Q86UP3
GGQATNKTSNCVVLK	MTRFR	71	Q9H3J6
VSAQATGKNVGCLQE	AARS1	936	P49588
GSGLVFSCQDKQNTV	NGFR	131	P08138
ECNGKTVTNGKQNAN	TMTC2	336	Q8N394
QNVSVGVSQSKAGSS	ZIK1	81	Q3SY52
GSNGFIAVNLSSCKQ	TTBK2	531	Q6IQ55
RKNTAVTGGANLVSC	WDR49	381	Q8IV35
LTQTGQCGNQIGAKF	TUBB8B	6	A6NNZ2
GNSFSCGNSQCVTKV	TMPRSS9	156	Q7Z410
GLQSNKNGTCVTNLT	SLAMF7	136	Q9NQ25
KRGTCTKQGGNTNAS	WDR53	291	Q7Z5U6
GKCSQHQGLSAVATA	nan	106	Q6ZVQ6
GCDIQNSVGSNIKSD	ZNF644	201	Q9H582
NGLNQCFTTTQGKAS	ZNF726	131	A6NNF4
ADGKCVQEGNKSSVQ	ZNF507	741	Q8TCN5
LSALQAGNKGTQACI	TLN2	1966	Q9Y4G6
AGNKGTQACITAATA	TLN2	1971	Q9Y4G6
STQIVANAKGAVTGA	PLIN2	101	Q99541
VITQGTSLKNAGNCL	PHGDH	356	O43175
QSQGNGSCSVKRHEV	TCTN3	406	Q6NUS6
CNASVTNSVKGTNAI	TNFRSF17	41	Q02223
NIQTDNNKSIGCFGS	PKP2	636	Q99959
IGNSNTGEKCQTVTL	ZNF836	61	Q6ZNA1
SASKSAPGCQEQTAN	INSYN2B	346	A6NMK8
VSAAANNNICGVGVA	PCSK2	216	P16519