Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	motile cilium assembly	DNHD1 CFAP43 CEP128 FSIP2 POC1B ULK4	5.21e-06	88	103	6	GO:0044458
GeneOntologyBiologicalProcess	sperm flagellum assembly	DNHD1 CFAP43 CEP128 FSIP2 POC1B	8.79e-06	56	103	5	GO:0120316
GeneOntologyBiologicalProcess	male gamete generation	DNHD1 ZBTB16 PNLDC1 CFAP43 RNF17 CEP128 AR SLC4A2 FANCA FSIP2 PSME4 POC1B VPS13B CFAP97	2.56e-05	762	103	14	GO:0048232
GeneOntologyBiologicalProcess	cilium movement	DNHD1 CAMSAP3 CFAP43 NPHP4 CEP128 FSIP2 POC1B ULK4	4.98e-05	261	103	8	GO:0003341
GeneOntologyBiologicalProcess	spermatid development	DNHD1 CFAP43 RNF17 CEP128 FSIP2 PSME4 POC1B VPS13B	5.12e-05	262	103	8	GO:0007286
GeneOntologyBiologicalProcess	spermatid differentiation	DNHD1 CFAP43 RNF17 CEP128 FSIP2 PSME4 POC1B VPS13B	6.65e-05	272	103	8	GO:0048515
GeneOntologyBiologicalProcess	spermatogenesis	DNHD1 ZBTB16 PNLDC1 CFAP43 RNF17 CEP128 AR SLC4A2 FSIP2 PSME4 POC1B VPS13B CFAP97	8.49e-05	744	103	13	GO:0007283
GeneOntologyBiologicalProcess	forebrain anterior/posterior pattern specification	FEZF2 WNT1	1.47e-04	4	103	2	GO:0021797
MousePheno	abnormal amacrine cell morphology	FOXN4 FAT3 NEUROD1 MEGF10 AGTPBP1	1.04e-06	31	84	5	MP:0005240
MousePheno	oligozoospermia	DNHD1 RAPGEF6 ZBTB16 CFAP43 NPHP4 CEP128 AR FSIP2 POC1B VPS13B EPB41L2 AGTPBP1	2.95e-06	384	84	12	MP:0002687
MousePheno	decreased germ cell number	DNHD1 RAPGEF6 ZBTB16 CFAP43 RNF17 NPHP4 CEP128 AR SLC4A2 FANCA FSIP2 POC1B VPS13B EPB41L2 AGTPBP1	1.27e-05	687	84	15	MP:0002209
MousePheno	abnormal sperm number	DNHD1 RAPGEF6 ZBTB16 CFAP43 RNF17 NPHP4 CEP128 AR SLC4A2 FSIP2 POC1B VPS13B EPB41L2 AGTPBP1	1.90e-05	624	84	14	MP:0002673
MousePheno	abnormal spermatogenesis	DNHD1 RAPGEF6 ZBTB16 PNLDC1 CFAP43 RNF17 NPHP4 CEP128 AR SLC4A2 FANCA FSIP2 PSME4 POC1B VPS13B EPB41L2 AGTPBP1	2.37e-05	910	84	17	MP:0001156
MousePheno	decreased male germ cell number	DNHD1 RAPGEF6 ZBTB16 CFAP43 RNF17 NPHP4 CEP128 AR SLC4A2 FSIP2 POC1B VPS13B EPB41L2 AGTPBP1	2.51e-05	640	84	14	MP:0004901
MousePheno	abnormal gametogenesis	DNHD1 RAPGEF6 ZBTB16 PNLDC1 CFAP43 RNF17 NPHP4 CEP128 AR SLC4A2 FANCA FSIP2 PSME4 POC1B VAV1 VPS13B EPB41L2 AGTPBP1	5.26e-05	1070	84	18	MP:0001929
MousePheno	abnormal gametes	DNHD1 RAPGEF6 ZBTB16 CFAP43 RNF17 NPHP4 CEP128 AR SLC4A2 FSIP2 PSME4 POC1B VPS13B EPB41L2 AGTPBP1	5.97e-05	785	84	15	MP:0001124
MousePheno	asthenozoospermia	DNHD1 RAPGEF6 ZBTB16 CFAP43 NPHP4 CEP128 FSIP2 PSME4 POC1B AGTPBP1	6.02e-05	362	84	10	MP:0002675
MousePheno	abnormal male reproductive system physiology	DNHD1 RAPGEF6 ZBTB16 CNTNAP1 CAMSAP3 DDO PNLDC1 CFAP43 RNF17 NPHP4 CEP128 AR SLC4A2 FANCA FSIP2 PSME4 POC1B VPS13B EPB41L2 AGTPBP1	8.96e-05	1329	84	20	MP:0003698
MousePheno	abnormal germ cell morphology	DNHD1 RAPGEF6 ZBTB16 CFAP43 RNF17 NPHP4 CEP128 AR SLC4A2 FANCA FSIP2 PSME4 POC1B VPS13B EPB41L2 AGTPBP1	1.39e-04	946	84	16	MP:0002208
MousePheno	abnormal sperm motility	DNHD1 RAPGEF6 ZBTB16 CFAP43 NPHP4 CEP128 FSIP2 PSME4 POC1B AGTPBP1	1.40e-04	401	84	10	MP:0002674
MousePheno	abnormal foam cell morphology	DNHD1 RAPGEF6 ZBTB16 CFAP43 RNF17 NPHP4 CEP128 AR SLC4A2 FANCA FSIP2 PSME4 POC1B VPS13B EPB41L2 AGTPBP1	1.53e-04	954	84	16	MP:0009840
MousePheno	abnormal male germ cell morphology	DNHD1 RAPGEF6 ZBTB16 CFAP43 RNF17 NPHP4 CEP128 AR SLC4A2 FSIP2 PSME4 POC1B VPS13B EPB41L2 AGTPBP1	1.63e-04	859	84	15	MP:0006362
MousePheno	absent pancreatic islets	NEUROD1 NEUROG3	2.12e-04	4	84	2	MP:0009173
MousePheno	abnormal somatic sensory system morphology	FEZF2 FOXN4 FAT3 CAMSAP3 SOSTDC1 CACHD1 NPHP4 AR PIKFYVE NEUROD1 NEUROG2 MEGF10 AGTPBP1	2.67e-04	702	84	13	MP:0000959
MousePheno	abnormal sperm physiology	DNHD1 RAPGEF6 ZBTB16 CFAP43 NPHP4 CEP128 FSIP2 PSME4 POC1B AGTPBP1	3.36e-04	447	84	10	MP:0004543
MousePheno	abnormal somatic nervous system morphology	ZBTB16 FEZF2 FOXN4 FAT3 CAMSAP3 SOSTDC1 CACHD1 NPHP4 AR PIKFYVE NEUROD1 DHX35 ECEL1 NEUROG2 MEGF10 AGTPBP1	3.46e-04	1025	84	16	MP:0002752
MousePheno	testicular atrophy	RAPGEF6 ZBTB16 AR AGTPBP1	4.29e-04	59	84	4	MP:0003205
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RAPGEF6 KHNYN NOB1 DDX56 NUP214 CFAP43 ANKHD1 NPHP4 AHDC1 FANCA PIKFYVE HIVEP3 PSME4 TRIB3 ADAMTS7 COQ4 PCNX4 NPRL3 ULK4 MYRF	9.46e-11	1105	104	20	35748872
Pubmed	Basic helix-loop-helix transcription factors cooperate to specify a cortical projection neuron identity.	FEZF2 NEUROD1 NEUROG2 NEUROG3	7.38e-08	14	104	4	18160702
Pubmed	neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS.	NEUROD1 NEUROG2 NEUROG3	5.16e-07	6	104	3	9000438
Pubmed	Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells.	WNT1 NEUROD1 NEUROG2	9.01e-07	7	104	3	14716020
Pubmed	Mash1 activates a cascade of bHLH regulators in olfactory neuron progenitors.	NEUROD1 NEUROG2 NEUROG3	9.01e-07	7	104	3	9108377
Pubmed	Myf5 is a novel early axonal marker in the mouse brain and is subjected to post-transcriptional regulation in neurons.	WNT1 NEUROD1 NEUROG2	3.07e-06	10	104	3	10603349
Pubmed	Cranial nerve development requires co-ordinated Shh and canonical Wnt signaling.	WNT1 NEUROD1 NEUROG2	7.27e-06	13	104	3	25799573
Pubmed	Neurogenin 3 and neurogenic differentiation 1 are retained in the cytoplasm of multiple endocrine neoplasia type 1 islet and pancreatic endocrine tumor cells.	NEUROD1 NEUROG3	8.86e-06	2	104	2	19307926
Pubmed	TRPM8-androgen receptor association within lipid rafts promotes prostate cancer cell migration.	AR TRPM8	8.86e-06	2	104	2	31501416
Pubmed	m6A-induced TRIB3 regulates Hippo pathway through interacting with LATS1 to promote the progression of lung adenocarcinoma.	LATS1 TRIB3	8.86e-06	2	104	2	38372068
Pubmed	Neurogenin2 directs granule neuroblast production and amplification while NeuroD1 specifies neuronal fate during hippocampal neurogenesis.	NEUROD1 NEUROG2	8.86e-06	2	104	2	19274100
Pubmed	Unraveling androgen receptor interactomes by an array-based method: discovery of proto-oncoprotein c-Rel as a negative regulator of androgen receptor.	REL AR	8.86e-06	2	104	2	17011549
Pubmed	Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation.	NEUROD1 NEUROG2	8.86e-06	2	104	2	22491944
Pubmed	Neuronal repair after spinal cord injury by in vivo astrocyte reprogramming mediated by the overexpression of NeuroD1 and Neurogenin-2.	NEUROD1 NEUROG2	8.86e-06	2	104	2	39135103
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	UBE2L6 SMC4 BAZ1B DDX56 DIS3 DARS2 GEMIN4 CPSF2	8.95e-06	341	104	8	32971831
Pubmed	Neurog2 controls the leading edge of neurogenesis in the mammalian retina.	NEUROD1 NEUROG2 NEUROG3	2.05e-05	18	104	3	20144606
Pubmed	The Mediator Subunit, Med23 Is Required for Embryonic Survival and Regulation of Canonical WNT Signaling During Cranial Ganglia Development.	SOSTDC1 NEUROD1 NEUROG2	2.05e-05	18	104	3	33192541
Pubmed	Expression of neurogenin3 reveals an islet cell precursor population in the pancreas.	NEUROD1 NEUROG2 NEUROG3	2.05e-05	18	104	3	10903178
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	RAPGEF6 MBNL1 NOB1 BAZ1B ZDHHC17 ANKHD1 DIS3 NEUROD1 PSME4 KCNH1 CPSF2 NFAT5 VPS13B	2.17e-05	1084	104	13	11544199
Pubmed	Neurog2 Deficiency Uncovers a Critical Period of Cell Fate Plasticity and Vulnerability among Neural-Crest-Derived Somatosensory Progenitors.	NEUROD1 TRPM8 NEUROG2	2.43e-05	19	104	3	31801063
Pubmed	Neurogenin 2 has an essential role in development of the dentate gyrus.	NEUROD1 NEUROG2 NEUROG3	2.43e-05	19	104	3	18448566
Pubmed	[Effect of osmotic response element binding protein on mucus secretion with hypertonicity in human airway epithelial cells].	NFAT5 MUC5AC	2.65e-05	3	104	2	21418859
Pubmed	SHANK2 is a frequently amplified oncogene with evolutionarily conserved roles in regulating Hippo signaling.	LATS1 ARHGEF7	2.65e-05	3	104	2	32661924
Pubmed	Neurogenin3 activates the islet differentiation program while repressing its own expression.	NEUROD1 NEUROG3	2.65e-05	3	104	2	14576336
Pubmed	Reversible expansion of pancreatic islet progenitors derived from human induced pluripotent stem cells.	NEUROD1 NEUROG3	2.65e-05	3	104	2	32065490
Pubmed	Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.	TRPM8 MUC5AC	2.65e-05	3	104	2	36675209
Pubmed	Expression of insulinoma-associated 2 (INSM2) in pancreatic islet cells is regulated by the transcription factors Ngn3 and NeuroD1.	NEUROD1 NEUROG3	2.65e-05	3	104	2	21343251
Pubmed	Androgen-receptor-interacting nuclear proteins.	RNF17 AR	2.65e-05	3	104	2	10961928
Pubmed	Islet cell differentiation in liver by combinatorial expression of transcription factors neurogenin-3, BETA2, and RIPE3b1.	NEUROD1 NEUROG3	2.65e-05	3	104	2	17239820
Pubmed	Induction of pancreatic islet cell differentiation by the neurogenin-neuroD cascade.	NEUROD1 NEUROG3	2.65e-05	3	104	2	17924961
Pubmed	Upregulation of DARS2 by HBV promotes hepatocarcinogenesis through the miR-30e-5p/MAPK/NFAT5 pathway.	DARS2 NFAT5	2.65e-05	3	104	2	29052520
Pubmed	Phylotypic expression of the bHLH genes Neurogenin2, Neurod, and Mash1 in the mouse embryonic forebrain.	NEUROD1 NEUROG2	2.65e-05	3	104	2	20058311
Pubmed	Involvement of Ngn2, Tbr and NeuroD proteins during postnatal olfactory bulb neurogenesis.	NEUROD1 NEUROG2	2.65e-05	3	104	2	19200230
Pubmed	Testosterone-androgen receptor: The steroid link inhibiting TRPM8-mediated cold sensitivity.	AR TRPM8	2.65e-05	3	104	2	32277850
Pubmed	Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.	NEUROD1 NEUROG3	2.65e-05	3	104	2	10757813
Pubmed	BTB/POZ zinc finger protein ZBTB16 inhibits breast cancer proliferation and metastasis through upregulating ZBTB28 and antagonizing BCL6/ZBTB27.	ZBTB16 BCL6B	2.65e-05	3	104	2	32517789
Pubmed	Polymorphic variations in the neurogenic differentiation-1, neurogenin-3, and hepatocyte nuclear factor-1alpha genes contribute to glucose intolerance in a South Indian population.	NEUROD1 NEUROG3	2.65e-05	3	104	2	15277395
Pubmed	Mash1 is required for generic and subtype differentiation of hypothalamic neuroendocrine cells.	NEUROD1 NEUROG2 NEUROG3	2.85e-05	20	104	3	16469766
Pubmed	beta-Catenin regulates intercellular signalling networks and cell-type specific transcription in the developing mouse midbrain-rhombomere 1 region.	APCDD1 WNT1 NEUROG2	2.85e-05	20	104	3	20532162
Pubmed	Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer.	ZBTB16 AR	5.29e-05	4	104	2	23798432
Pubmed	Gene dosage changes in KCTD13 result in penile and testicular anomalies via diminished androgen receptor function.	ZBTB16 AR	5.29e-05	4	104	2	36196997
Pubmed	Requirement of multiple basic helix-loop-helix genes for retinal neuronal subtype specification.	NEUROD1 NEUROG2	5.29e-05	4	104	2	15105417
Pubmed	Geminin regulates neuronal differentiation by antagonizing Brg1 activity.	NEUROD1 NEUROG2	5.29e-05	4	104	2	16024661
Pubmed	Identification of palmitoyltransferase and thioesterase enzymes that control the subcellular localization of axon survival factor nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2).	LYPLA2 ZDHHC17	5.29e-05	4	104	2	25271157
Pubmed	NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway.	NPHP4 LATS1	5.29e-05	4	104	2	21555462
Pubmed	ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.	USP51 USP27X	5.29e-05	4	104	2	27132940
Pubmed	The Growth arrest specific 1 (Gas1) gene is transcriptionally regulated by NeuroD1 via two distal E-boxes.	NEUROD1 NEUROG2	5.29e-05	4	104	2	29395133
Pubmed	Bile salt-stimulated carboxyl ester lipase influences lipoprotein assembly and secretion in intestine: a process mediated via ceramide hydrolysis.	NEUROD1 NEUROG3	5.29e-05	4	104	2	11733511
Pubmed	Inactivation of AR/TMPRSS2-ERG/Wnt signaling networks attenuates the aggressive behavior of prostate cancer cells.	WNT1 AR	5.29e-05	4	104	2	21680704
Pubmed	Regulation of neuroD2 expression in mouse brain.	NEUROD1 NEUROG2	5.29e-05	4	104	2	14697366
Pubmed	GDF11 controls the timing of progenitor cell competence in developing retina.	FOXN4 NEUROD1 NEUROG2	5.69e-05	25	104	3	15976303
Pubmed	A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation.	NEUROD1 NEUROG2 NEUROG3	6.42e-05	26	104	3	32857951
Pubmed	DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells.	ZBTB16 BCL6B NEUROG3	8.06e-05	28	104	3	24850856
Pubmed	Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14.	MUC5AC MUC7	8.80e-05	5	104	2	12507512
Pubmed	Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12.	MUC5AC MUC7	8.80e-05	5	104	2	12135769
Pubmed	Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos.	WNT1 AR	8.80e-05	5	104	2	3594566
Pubmed	The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF.	ZBTB16 REL	8.80e-05	5	104	2	25865065
Pubmed	Visualization of bHLH transcription factor interactions in living mammalian cell nuclei and developing chicken neural tube by FRET.	NEUROD1 NEUROG2	8.80e-05	5	104	2	16775630
Pubmed	Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex.	NEUROG2 NEUROG3	8.80e-05	5	104	2	19168665
Pubmed	Complex regulation of human androgen receptor expression by Wnt signaling in prostate cancer cells.	WNT1 AR	8.80e-05	5	104	2	16474850
Pubmed	Disruption of the basal body protein POC1B results in autosomal-recessive cone-rod dystrophy.	NPHP4 POC1B	8.80e-05	5	104	2	25018096
Pubmed	JMJD1C Exhibits Multiple Functions in Epigenetic Regulation during Spermatogenesis.	ZBTB16 BCL6B PSME4	8.97e-05	29	104	3	27649575
Pubmed	Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos.	FANCA TRIB3 NEUROG2	9.94e-05	30	104	3	31789450
Pubmed	Generation of functional multipotent adult stem cells from GPR125+ germline progenitors.	ZBTB16 BCL6B MUC5AC	9.94e-05	30	104	3	17882221
Pubmed	pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development.	WNT1 NEUROD1 NEUROG3	9.94e-05	30	104	3	17257418
Pubmed	BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.	ZBTB16 BAZ1B NUP214	1.10e-04	31	104	3	23086144
Pubmed	Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.	SOSTDC1 NEUROD1 NEUROG3	1.21e-04	32	104	3	27292642
Pubmed	Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth.	AR SACS	1.32e-04	6	104	2	34429451
Pubmed	A bipotential precursor population for pancreas and liver within the embryonic endoderm.	NEUROD1 NEUROG3	1.32e-04	6	104	2	11222142
Pubmed	Combinatorial receptor codes for odors.	OR56A5 OR56A4	1.32e-04	6	104	2	10089886
Pubmed	A peptide aptamer to antagonize BCL-6 function.	ZBTB16 BCL6B	1.32e-04	6	104	2	16331266
Pubmed	Nef-mediated lipid raft exclusion of UbcH7 inhibits Cbl activity in T cells to positively regulate signaling.	ARHGEF7 VAV1	1.32e-04	6	104	2	16356860
Pubmed	Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor.	UBE2L6 AR	1.32e-04	6	104	2	10085091
Pubmed	IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas.	NEUROD1 NEUROG3	1.32e-04	6	104	2	16511571
Pubmed	Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis.	NEUROD1 NEUROG2	1.32e-04	6	104	2	9806930
Pubmed	Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA.	NEUROD1 TRPM8 NEUROG2	1.33e-04	33	104	3	30917309
Pubmed	Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.	FAT3 ARHGEF7 NFAT5	1.33e-04	33	104	3	24204828
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	VPS37A ZBTB16 MRPL42 MBNL1 CAMSAP3 DDX56 AHDC1 AR HIVEP3 GTF2H2 PCNX4 SLC9A7 NFAT5 VPS13B	1.42e-04	1489	104	14	28611215
Pubmed	Fgf15-mediated control of neurogenic and proneural gene expression regulates dorsal midbrain neurogenesis.	WNT1 NEUROD1 NEUROG2	1.45e-04	34	104	3	21172336
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RAPGEF6 CAMSAP3 ZDHHC17 ANKHD1 DIS3 SLC4A2 FANCA PSME4 ARHGEF7	1.49e-04	650	104	9	38777146
Pubmed	Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon.	FEZF2 WNT1 NEUROG2	1.73e-04	36	104	3	18094027
Pubmed	Coupling of cell migration with neurogenesis by proneural bHLH factors.	NEUROD1 NEUROG2	1.84e-04	7	104	2	16432194
Pubmed	Regulation of Neurogenesis in Mouse Brain by HMGB1.	WNT1 NEUROD1 NEUROG2	1.87e-04	37	104	3	32708917
Pubmed	Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling.	ARL13B NEUROG2 NEUROG3	2.03e-04	38	104	3	25936505
Pubmed	The zinc finger transcription factor RP58 negatively regulates Rnd2 for the control of neuronal migration during cerebral cortical development.	NEUROD1 NEUROG2	2.45e-04	8	104	2	24084125
Pubmed	Dual requirement for Pax6 in retinal progenitor cells.	NEUROD1 NEUROG2	2.45e-04	8	104	2	19004853
Pubmed	Neurog2 Acts as a Classical Proneural Gene in the Ventromedial Hypothalamus and Is Required for the Early Phase of Neurogenesis.	NEUROG2 NEUROG3	2.45e-04	8	104	2	32273485
Pubmed	High-density molecular map of the central span of the mouse X chromosome.	AR PHKA1	2.45e-04	8	104	2	1675191
Pubmed	Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.	AR PHKA1	2.45e-04	8	104	2	2034279
Pubmed	The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling.	WNT1 NEUROG2	2.45e-04	8	104	2	23648512
Pubmed	Expression of mouse Foxi class genes in early craniofacial development.	NEUROD1 NEUROG2	2.45e-04	8	104	2	15376323
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZDHHC17 DIS3 PIKFYVE MYRF	2.56e-04	102	104	4	10231032
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	MBNL1 NOB1 SMC4 DDX56 TBC1D8B DIS3 GTF2H2 CPSF2 VAV1	2.61e-04	701	104	9	30196744
Pubmed	Placentation defects are highly prevalent in embryonic lethal mouse mutants.	CAMSAP3 ARHGEF7 COQ4 DHX35	2.66e-04	103	104	4	29539633
Pubmed	Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation.	FOXN4 NEUROD1 NEUROG2	2.74e-04	42	104	3	30485816
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	KNTC1 ANKHD1 NPHP4 PSME4 COQ4 ARL13B GEMIN4 MUC5AC	3.00e-04	564	104	8	21565611
Pubmed	Identification of disease-relevant modulators of the SHH pathway in the developing brain.	ARL13B ULK4	3.14e-04	9	104	2	34463328
Pubmed	Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network.	NEUROD1 NEUROG3	3.14e-04	9	104	2	18560595
Pubmed	Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: HuGE review.	AR DCLRE1C	3.14e-04	9	104	2	14726805
Pubmed	DNA cross-link repair safeguards genomic stability during premeiotic germ cell development.	ZBTB16 FANCA	3.14e-04	9	104	2	31367016
GeneFamily	Olfactory receptors, family 56	OR56A5 OR56A4	4.65e-04	9	66	2	167
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FAT3 DDO SVEP1 HIVEP3 ADAMTS7 MEGF10	2.98e-06	170	104	6	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT3 NEUROD1 MLIP PTPRO KCNH1 EPB41L2	3.88e-06	178	104	6	ccea3c8908d72f5fecd151a133048c8e9758304c
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	FEZF2 MRPL42 SMC4 NEUROD1 ECEL1 NEUROG2	7.35e-06	199	104	6	399e73d45638848e68edda120316ceff04d98680
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Cortical_neuron\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	FAT3 NEUROD1 ADAMTS7 PTPRO FBXL2 NEUROG2	7.56e-06	200	104	6	7bba2ff09349c8db3d1ccf53520b12cbf7b0abac
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	FEZF2 MRPL42 SMC4 NEUROD1 ECEL1 NEUROG2	7.56e-06	200	104	6	c792d1dbbe27ebd60f4770834f30882c1a625be5
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Pcdh11x_(Neuron.Gad1Gad2.Synpr-Pcdh11x)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SOSTDC1 FANCA TRPM8 MUC5AC	1.11e-05	59	104	4	439a9d56eeecccd70a4defb430e228329655cb80
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Pcdh11x_(Neuron.Gad1Gad2.Synpr-Pcdh11x)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SOSTDC1 FANCA TRPM8 MUC5AC	1.11e-05	59	104	4	50432c7b52fd197e8856ba0296c34cf66a2faaf5
Disease	NAD(P)H dehydrogenase [quinone] 1 measurement	NOB1 NFAT5	3.40e-05	3	100	2	EFO_0803303
Disease	chronic kidney disease	MBNL1 CPS1 NPHP4 DHX35 CPSF2 NFAT5	1.53e-04	235	100	6	EFO_0003884
Disease	Respiratory Distress Syndrome, Newborn	ABCA3 MEGF10	1.69e-04	6	100	2	C0035220
Disease	diastolic blood pressure, social deprivation	ST7L ULK4	1.69e-04	6	100	2	EFO_0006336, EFO_0009696
Disease	glucose intolerance (is_implicated_in)	NEUROD1 NEUROG3	3.14e-04	8	100	2	DOID:10603 (is_implicated_in)
Disease	Distal arthrogryposis	ECEL1 TNNI2	4.03e-04	9	100	2	cv:C0265213
Disease	glioblastoma (implicated_via_orthology)	USP51 USP27X	4.03e-04	9	100	2	DOID:3068 (implicated_via_orthology)
Disease	gallstones	CPS1 POC1B NFAT5 MUC5AC	5.08e-04	108	100	4	EFO_0004210
Disease	diastolic blood pressure, alcohol drinking	ST7L POC1B NPRL3 ULK4	7.09e-04	118	100	4	EFO_0004329, EFO_0006336
Disease	Renal dysplasia and retinal aplasia (disorder)	NPHP4 POC1B	7.34e-04	12	100	2	C0403553
Disease	uric acid measurement	FAT3 BAZ1B CPS1 AR FANCA MLIP NFAT5 EPB41L2	1.12e-03	610	100	8	EFO_0004761
Disease	distal arthrogryposis (implicated_via_orthology)	ECEL1 TNNI2	1.16e-03	15	100	2	DOID:0050646 (implicated_via_orthology)
Disease	urolithiasis	CPS1 VPS13B EPB41L2	1.29e-03	63	100	3	MONDO_0024647
Disease	metabolite measurement, diet measurement	CPS1 PDXDC2P MYRF	1.83e-03	71	100	3	EFO_0004725, EFO_0008111
Disease	diet measurement, HOMA-B	FAT3 NFAT5	1.87e-03	19	100	2	EFO_0004469, EFO_0008111
Disease	Adenocarcinoma of prostate	AR FANCA	2.08e-03	20	100	2	C0007112
Disease	alanine measurement	CPS1 KCNH1 PDXDC2P	3.15e-03	86	100	3	EFO_0009765
Disease	Cerebral Astrocytoma	AR LATS1	3.24e-03	25	100	2	C0750935
Disease	Intracranial Astrocytoma	AR LATS1	3.24e-03	25	100	2	C0750936
Disease	Astrocytoma	AR LATS1	3.24e-03	25	100	2	C0004114
Disease	Grade I Astrocytoma	AR LATS1	3.24e-03	25	100	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	AR LATS1	3.24e-03	25	100	2	C0205768
Disease	Mixed oligoastrocytoma	AR LATS1	3.24e-03	25	100	2	C0547065
Disease	Neonatal diabetes mellitus	NEUROD1 NEUROG3	3.24e-03	25	100	2	C0158981
Disease	Pilocytic Astrocytoma	AR LATS1	3.24e-03	25	100	2	C0334583
Disease	Juvenile Pilocytic Astrocytoma	AR LATS1	3.24e-03	25	100	2	C0280783
Disease	Diffuse Astrocytoma	AR LATS1	3.24e-03	25	100	2	C0280785
Disease	Childhood Cerebral Astrocytoma	AR LATS1	3.24e-03	25	100	2	C0338070
Disease	cholelithiasis	CPS1 NFAT5 VPS13B	3.36e-03	88	100	3	EFO_0004799

Protein segments in the cluster

Peptide	Gene	Start	Entry
PKHHILILPAVDSYQ	CATR1	21	Q13166
YERLHLLLMPPKHHP	SLC4A2	1136	P04920
LLLMPPKHHPDVTYV	SLC4A2	1141	P04920
PKDDLYPLLHPTMHC	CFAP43	246	Q8NDM7
ELHHFPPTSPLKDYG	CEP128	121	Q6ZU80
KAAHEYHPGSKPPLP	CNTNAP1	1321	P78357
IPRSADHPPKLYHSA	CFAP97	411	Q9P2B7
PHEGKHTPLYERSLP	C9orf129	71	Q5T035
SHPDPLHLGALPYAV	CPSF2	61	Q9P2I0
LVALLHKHLPGHPYV	BAZ1B	1436	Q9UIG0
PPLHTDIIHYENIPK	CACHD1	531	Q5VU97
YLVAHPTLIDPKGHA	CACHD1	846	Q5VU97
YPGLPSHPQHELVKR	CTH	291	P32929
EHPFNHSKEPLPLAV	ABCA3	136	Q99758
SKPAPLTPAYHTLPH	ARHGEF7	611	Q14155
HHNDFYRKPLPPLAV	ARL13B	401	Q3SXY8
KYHLGSPHIIPKSPL	DNHD1	1606	Q96M86
PHAKSERPSHPLYEP	AHDC1	186	Q5TGY3
SPDLHPTIYHAKGLL	AGTPBP1	986	Q9UPW5
PHDVDSLPHLRKFSP	CAMSAP3	801	Q9P1Y5
APARPGHAQPHVVYK	ADAMTS7	171	Q9UKP4
YPPAKSLLHPQTLSH	MLIP	391	Q5VWP3
PEPGELLTHLYSHLK	ITPKC	306	Q96DU7
ILHHLIPPALNPIVY	OR56A4	281	Q8NGH8
LPKNSHIPCHYDLLP	MEGF10	1101	Q96KG7
HVPKHLPPALYKLHL	PODN	231	Q7Z5L7
LPHVKVHAYFAPVTP	FBXL2	391	Q9UKC9
PQLLAHLVSHYPTIP	OR1B1	81	Q8NGR6
TPLHISGFHLPYKPK	NOB1	121	Q9ULX3
PDKHRYAPHLPIARD	NEUROG2	256	Q9H2A3
IADHSLYALEPPAPH	NEUROG3	141	Q9Y4Z2
KHLLHQNPSVPPYES	LATS1	561	O95835
HLLAHTAPHPKLAPT	PHKA1	666	P46020
HPAVVKPHLGHVPDY	DDX56	481	Q9NY93
KDSHALPPYITVLPH	FSIP2	5101	Q5CZC0
HHTFYRLVSPEQPPK	EPB41L2	491	O43491
VLKYAGHPPFEHSPI	PER3	326	P56645
PLGYPIYSSKPLHIH	PCNX4	1156	Q63HM2
PAVPAVTLYKHDPAL	PDXDC2P	306	Q6P474
LPHKIHYAASSLIPP	NPRL3	231	Q12980
EAPKTPPHIILHYCV	KCNH1	201	O95259
PSLLPHAAPFAKSHL	NUP214	1026	P35658
IGKPAHLIVSLYEHP	KNTC1	1766	P50748
YKHHPALSPIARGPS	MUC5AC	36	P98088
PHPHARIKLENPLDY	AR	381	P10275
LDIYPRTPHPHEEKV	POC1B	326	Q8TC44
VKVPPYHDQHITLPV	NFAT5	506	O94916
PEHPLPRLKYTHDQL	ECEL1	696	O95672
QYTLKPHPALEPAFH	NPHP4	186	O75161
VSHEPKQHRTAPYPP	PTPRO	211	Q16827
LIPHTYPDTPIHTQK	DDO	51	Q99489
ILHHLIPPALNPIVY	OR56A5	281	P0C7T3
PHYPGLLAHQKPFIR	MUC7	46	Q8TAX7
HVPPHPADQKEYLIS	PIKFYVE	536	Q9Y2I7
PLVCHPHALLVYPTL	GNPTG	166	Q9UJJ9
KHLPTLDHPIIPADY	CPS1	1291	P31327
AHVLIHTGEKPYPCP	BCL6B	401	Q8N143
LRHKVPYPETFHPEV	DCLRE1C	401	Q96SD1
LHIHPASVLYAEKPP	DHX35	636	Q9H5Z1
VHILHPPLVPGKYRS	FANCA	491	O15360
GLPYKHLITHHQEPP	CFAP107	76	Q8N1D5
PVKHSLIPVYIHVLP	FAT3	2686	Q8TDW7
PLYSHHLPTSPLQKG	COQ4	36	Q9Y3A0
YRSDEHHPPILPPKA	APCDD1	271	Q8J025
CKYLHPPPHLKTQLE	MBNL1	66	Q9NR56
TIRLPHVKYICPHAP	LYPLA2	46	O95372
HVKYICPHAPRIPVT	LYPLA2	51	O95372
AAPVSLPLPAHLHVF	KLHDC7B	311	Q96G42
PELQDEIHYPPKLHC	KHNYN	76	O15037
HPLIKKYIHSPLPSA	SACS	861	Q9NZJ4
LAADKFPHPAPYPHK	FEZF2	221	Q8TBJ5
YTKPDAIHPHPLLQR	OSGIN1	41	Q9UJX0
HSSQELHPKHYPKPI	FOXN4	181	Q96NZ1
SHYKELLTHHLSPPP	GTF2H2C;	226	Q6P1K8
APHPSDIHLLYTEPK	DARS2	506	Q6PI48
EGPHTHLKPPDYSVA	RAPGEF6	1521	Q8TEU7
ALPAAVHTYHVELKP	PRLHR	191	P49683
YHTVPLPPKGRVLIH	TMEM126B	171	Q8IUX1
AHLLLQKIYHIDPVP	PNLDC1	366	Q8NA58
VTPHPPYHLGAVAKT	SVEP1	2646	Q4LDE5
EFSEHALLRKHPAPP	DIS3	681	Q9Y2L1
SLPLAYPHPHFALLA	ANKHD1	1846	Q8IWZ3
EKNTTLHYHPPILPK	RNF17	661	Q9BXT8
LHYHPPILPKEMTDV	RNF17	666	Q9BXT8
KQNYLAEHCPPLHIP	TNNI2	41	P48788
GSRTPHIPYKLLHLI	USP51	421	Q70EK9
GNPSPHVPYKLLHLV	USP27X	136	A6NNY8
PPEKHLGIYSVLPNH	ZBTB16	326	Q05516
PVLKHHDPSLPYLEQ	TBC1D8B	821	Q0IIM8
SHYKELLTHHVSPPP	GTF2H2	226	Q13888
AVLEPYARLPPHKHV	TRIB3	106	Q96RU7
YARLPPHKHVARPTE	TRIB3	111	Q96RU7
SLQEKAAHPHPPEPY	WDR97	1501	A6NE52
YHPSVDIPYEHTKPI	MRPL42	61	Q9Y6G3
KPYVHGPPQDLSVHL	VAV1	656	P15498
HALLLPDQPPYHLKA	UBE2L6	36	O14933
HPVAQTPLHEKPYLP	HIVEP3	1126	Q5T1R4
LALVFALHHYKPTPL	SMC4	1201	Q9NTJ3
PTFHHVSVYPKKELP	ST7L	496	Q8TDW4
VTKNDPYKPHPHDLV	REL	66	Q04864
IFLPTSLPPELHHKG	PSME4	216	Q14997
ILYSHVVKPVPAHPS	SOSTDC1	31	Q6X4U4
PLLHPEEIKPQSHYN	ZDHHC17	26	Q8IUH5
HKPPSPHDLVYFEKS	WNT1	281	P04628
PPSTVKTYHYLVDPH	VPS13B	3986	Q7Z7G8
HSVPHPPELVLYSLV	TRPM8	761	Q7Z2W7
HNYLKPILTHSGPPL	SLC9A7	606	Q96T83
EKPVISVYPPIRHHL	VPS37A	76	Q8NEZ2
HILLEPDPVPAYALK	ULK4	996	Q96C45
AHKYLPALDEFPHPP	GEMIN4	186	P57678
HHKSLEPLASPAVPF	MYRF	951	Q9Y2G1
HVKPPPHAYSAALEP	NEUROD1	241	Q13562