Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

1.06e-08261246GO:0005248
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

1.63e-08141245GO:0031402
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

5.05e-07261245GO:0031420
GeneOntologyMolecularFunctionsodium channel activity

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

8.18e-07521246GO:0005272
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN11A SLC13A3 SLC13A2 SCN1A SCN2A SCN3A SCN8A SCN9A

1.16e-051711248GO:0015081
GeneOntologyMolecularFunctionL-isoleucine transmembrane transporter activity

SLC43A2 SLC43A1

1.14e-0431242GO:0015188
GeneOntologyMolecularFunctionsodium:dicarboxylate symporter activity

SLC13A3 SLC13A2

1.14e-0431242GO:0017153
GeneOntologyMolecularFunctioncoumarin 7-hydroxylase activity

CYP2A6 CYP2A13

1.14e-0431242GO:0008389
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SCN11A TRPA1 SLC13A3 SLC13A2 SLC46A3 SCN1A SCN2A SCN3A GHITM SCN8A SCN9A

1.54e-0446512411GO:0046873
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR5P3 OR10A7 TRPA1 P2RY12 GPR33 OR10P1 ESR1 OR6C65 TEK OR10J1 OR51A7 INTS6 ADRA2C GPR61 ADGRG2 PTCH2 TAS2R30 OR13C7 FCAMR NOTCH1

2.48e-04135312420GO:0004888
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SCN11A TRPA1 SLC13A3 SLC13A2 RHCE SLC46A3 SCN1A SCN2A SCN3A GHITM SCN8A SCN9A

5.36e-0462712412GO:0022890
GeneOntologyMolecularFunctionsuccinate transmembrane transporter activity

SLC13A3 SLC13A2

5.65e-0461242GO:0015141
GeneOntologyMolecularFunctionalpha-ketoglutarate transmembrane transporter activity

SLC13A3 SLC13A2

5.65e-0461242GO:0015139
GeneOntologyMolecularFunctionL-leucine transmembrane transporter activity

SLC43A2 SLC43A1

5.65e-0461242GO:0015190
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP1A1 CYP2A6 CYP2A13

6.13e-04271243GO:0008391
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH3 MYH7B MYO1F DYNC1H1 KIF2C

8.52e-041181245GO:0003774
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SCN11A TRPA1 ANO1 SLC13A3 SLC13A2 RHCE SLC46A3 SCN1A SCN2A SCN3A GHITM SCN8A SCN9A

8.73e-0475812413GO:0015318
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SCN11A TRPA1 ANO1 SLC13A3 SLC13A2 SLC46A3 SCN1A SCN2A SCN3A GHITM SCN8A SCN9A

8.85e-0466412412GO:0008324
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC43A2 SCN11A TRPA1 SLC43A1 ANO1 SLC13A3 SLC13A2 ABCA8 RHCE SLC46A3 SLC35B4 SCN1A SCN2A SCN3A GHITM SCN8A SCN9A

1.00e-03118012417GO:0022857
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR5P3 OR10A7 P2RY12 GPR33 OR10P1 ESR1 OR6C65 OR10J1 OR51A7 ADRA2C GPR61 ADGRG2 TAS2R30 OR13C7

1.19e-0388412414GO:0004930
GeneOntologyMolecularFunctionsteroid hydroxylase activity

CYP1A1 CYP2A6 CYP2A13

1.22e-03341243GO:0008395
GeneOntologyMolecularFunctionaromatase activity

CYP1A1 CYP2A6 CYP2A13

1.32e-03351243GO:0070330
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SCN11A TRPA1 ANO1 SCN1A SCN2A SCN3A SCN8A SCN9A

1.37e-033431248GO:0005261
GeneOntologyMolecularFunctionbranched-chain amino acid transmembrane transporter activity

SLC43A2 SLC43A1

1.67e-03101242GO:0015658
GeneOntologyMolecularFunctiontransporter activity

SLC43A2 SCN11A TRPA1 SLC43A1 ANO1 SLC13A3 SLC13A2 ABCA8 RHCE SLC46A3 SLC35B4 SCN1A SCN2A SCN3A GHITM SCN8A SCN9A

2.57e-03128912417GO:0005215
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

7.37e-08361256GO:0086010
GeneOntologyBiologicalProcesscardiac muscle cell contraction

AKAP6 SCN11A MYH7B SCN1A SCN2A SCN3A SCN8A SCN9A

9.61e-08931258GO:0086003
GeneOntologyBiologicalProcessneuronal action potential

SCN11A TRPA1 SCN1A SCN2A SCN3A SCN8A SCN9A

1.06e-07631257GO:0019228
GeneOntologyBiologicalProcessactin-mediated cell contraction

AKAP6 SCN11A MYH7B SCN1A SCN2A SCN3A SCN8A SCN9A

1.07e-061271258GO:0070252
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

2.04e-06621256GO:0086002
GeneOntologyBiologicalProcessactin filament-based movement

AKAP6 SCN11A MYH7B SCN1A SCN2A SCN3A SCN8A SCN9A

4.31e-061531258GO:0030048
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN11A TRPA1 SCN1A SCN2A SCN3A SCN8A SCN9A

5.42e-061121257GO:0019226
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception of pain

SCN11A TRPA1 ANO1 SCN1A SCN9A

6.04e-06431255GO:0062149
GeneOntologyBiologicalProcesscardiac muscle contraction

AKAP6 SCN11A MYH7B SCN1A SCN2A SCN3A SCN8A SCN9A

8.22e-061671258GO:0060048
GeneOntologyBiologicalProcessresponse to pain

SCN11A TRPA1 OSM SCN3A SCN9A

1.42e-05511255GO:0048265
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

1.48e-05871256GO:0086001
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception of pain

SCN11A TRPA1 ANO1 SCN1A

1.73e-05261254GO:0050966
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception

SCN11A TRPA1 ANO1 SCN1A SCN9A

2.45e-05571255GO:0050974
GeneOntologyBiologicalProcessphenylpropanoid metabolic process

CYP1A1 CYP2A6 CYP2A13

2.53e-05101253GO:0009698
GeneOntologyBiologicalProcesscoumarin metabolic process

CYP1A1 CYP2A6 CYP2A13

2.53e-05101253GO:0009804
GeneOntologyBiologicalProcessaction potential

AKAP6 SCN11A TRPA1 SCN1A SCN2A SCN3A SCN8A SCN9A

3.14e-052011258GO:0001508
GeneOntologyBiologicalProcessnegative regulation of L-leucine import across plasma membrane

SLC43A2 SLC43A1

3.64e-0521252GO:1905533
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN11A SLC13A3 SLC13A2 SCN1A SCN2A SCN3A SCN8A SCN9A

4.01e-052081258GO:0035725
GeneOntologyBiologicalProcessbehavioral response to pain

SCN11A OSM SCN3A SCN9A

4.05e-05321254GO:0048266
GeneOntologyBiologicalProcesssensory perception of pain

SCN11A TRPA1 ACP3 ANO1 SCN1A SCN9A

4.33e-051051256GO:0019233
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR5P3 SCN11A OR10A7 TRPA1 OR10P1 ANO1 OR6C65 OR10J1 OR51A7 SCN1A SCN9A TAS2R30 OR13C7

5.36e-0558212513GO:0050906
GeneOntologyBiologicalProcessstriated muscle contraction

AKAP6 SCN11A MYH7B SCN1A SCN2A SCN3A SCN8A SCN9A

5.41e-052171258GO:0006941
GeneOntologyBiologicalProcesssensory perception of temperature stimulus

SCN11A TRPA1 ANO1 SCN9A

8.09e-05381254GO:0050951
GeneOntologyBiologicalProcessdetection of mechanical stimulus

SCN11A TRPA1 ANO1 SCN1A SCN9A

9.27e-05751255GO:0050982
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

AKAP6 OR5P3 SCN11A OR10A7 UBQLN2 P2RY12 GPR33 OR10P1 ESR1 ANXA7 ACP3 ANO1 OR6C65 OR10J1 ADCY8 OR51A7 ADRA2C GPR61 ADGRG2 TAS2R30 OR13C7

9.45e-05139512521GO:0007186
GeneOntologyBiologicalProcessmembrane depolarization

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

9.56e-051211256GO:0051899
GeneOntologyBiologicalProcessregulation of L-leucine import across plasma membrane

SLC43A2 SLC43A1

1.09e-0431252GO:1905532
GeneOntologyBiologicalProcessnegative regulation of amine transport

SLC43A2 P2RY12 SLC43A1 ADRA2C

1.32e-04431254GO:0051953
GeneOntologyBiologicalProcesscirculatory system process

AKAP6 SCN11A TRPA1 MYH7B SH3GL2 SLC13A3 TEK BCR ADRA2C SCN1A SCN2A SCN3A SCN8A SCN9A

1.45e-0473312514GO:0003013
GeneOntologyBiologicalProcessblood circulation

AKAP6 SCN11A TRPA1 MYH7B SH3GL2 TEK BCR ADRA2C SCN1A SCN2A SCN3A SCN8A SCN9A

1.57e-0464812513GO:0008015
GeneOntologyBiologicalProcessmuscle contraction

AKAP6 SCN11A TRPA1 MYH7B ADRA2C SCN1A SCN2A SCN3A SCN8A SCN9A

1.65e-0440012510GO:0006936
GeneOntologyBiologicalProcesspositive regulation of insulin secretion involved in cellular response to glucose stimulus

TRPA1 ANO1 ADCY8 HCFC1

2.58e-04511254GO:0035774
GeneOntologyBiologicalProcesssodium ion transport

SCN11A SLC13A3 SLC13A2 SCN1A SCN2A SCN3A SCN8A SCN9A

2.76e-042751258GO:0006814
GeneOntologyBiologicalProcessretinal cone cell differentiation

CASZ1 DIO3 NOTCH1

3.08e-04221253GO:0042670
GeneOntologyBiologicalProcessepoxygenase P450 pathway

CYP1A1 CYP2A6 CYP2A13

3.08e-04221253GO:0019373
GeneOntologyBiologicalProcesscardiac vascular smooth muscle cell development

PBRM1 NOTCH1

3.60e-0451252GO:0060948
GeneOntologyBiologicalProcessL-leucine import across plasma membrane

SLC43A2 SLC43A1

3.60e-0451252GO:1903801
GeneOntologyBiologicalProcessbehavioral response to chemical pain

SCN11A SCN9A

3.60e-0451252GO:0061366
GeneOntologyBiologicalProcessbehavioral response to formalin induced pain

SCN11A SCN9A

3.60e-0451252GO:0061368
GeneOntologyBiologicalProcessisoleucine transport

SLC43A2 SLC43A1

3.60e-0451252GO:0015818
GeneOntologyBiologicalProcesspositive regulation of peptide hormone secretion

TRPA1 ANXA7 ANO1 ADCY8 ARHGEF7 HCFC1

3.93e-041571256GO:0090277
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

AKAP6 SCN11A UBQLN1 TRPA1 P2RY12 ANO1 SLC13A3 SLC13A2 RHCE SLC46A3 SCN1A SCN2A SCN3A GHITM SCN8A SCN9A

4.33e-04101712516GO:0098660
GeneOntologyBiologicalProcessdetection of stimulus

OR5P3 SCN11A OR10A7 TRPA1 OR10P1 ANO1 OR6C65 OR10J1 OR51A7 SCN1A SCN9A TAS2R30 OR13C7

4.44e-0472212513GO:0051606
GeneOntologyBiologicalProcesspositive regulation of peptide secretion

TRPA1 ANXA7 ANO1 ADCY8 ARHGEF7 HCFC1

4.50e-041611256GO:0002793
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

AKAP6 SCN11A UBQLN1 TRPA1 P2RY12 SLC13A3 SLC13A2 RHCE SLC46A3 SCN1A SCN2A SCN3A GHITM SCN8A SCN9A

4.67e-0492212515GO:0098662
GeneOntologyBiologicalProcessheart contraction

AKAP6 SCN11A MYH7B SCN1A SCN2A SCN3A SCN8A SCN9A

4.72e-042981258GO:0060047
GeneOntologyBiologicalProcessmuscle system process

AKAP6 SCN11A TRPA1 MYH7B ADRA2C SCN1A SCN2A SCN3A SCN8A SCN9A NOTCH1

5.02e-0454712511GO:0003012
GeneOntologyBiologicalProcessdetection of temperature stimulus involved in sensory perception of pain

SCN11A ANO1 SCN9A

5.10e-04261253GO:0050965
GeneOntologyBiologicalProcessepidermal cell fate specification

PTCH2 NOTCH1

5.38e-0461252GO:0009957
GeneOntologyBiologicalProcesssuccinate transmembrane transport

SLC13A3 SLC13A2

5.38e-0461252GO:0071422
GeneOntologyBiologicalProcesssuccinate transport

SLC13A3 SLC13A2

5.38e-0461252GO:0015744
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

AKAP6 SCN11A UBQLN1 TRPA1 P2RY12 ANO1 SLC13A3 SLC13A2 SLC46A3 SCN1A SCN2A SCN3A GHITM SCN8A SCN9A

5.84e-0494212515GO:0098655
GeneOntologyBiologicalProcessheart process

AKAP6 SCN11A MYH7B SCN1A SCN2A SCN3A SCN8A SCN9A

5.99e-043091258GO:0003015
GeneOntologyBiologicalProcessregulation of nucleotide-excision repair

ARID1B PBRM1 ACTL6B

7.08e-04291253GO:2000819
GeneOntologyBiologicalProcessalpha-ketoglutarate transport

SLC13A3 SLC13A2

7.50e-0471252GO:0015742
GeneOntologyBiologicalProcessnegative regulation of photoreceptor cell differentiation

CASZ1 NOTCH1

7.50e-0471252GO:0046533
GeneOntologyBiologicalProcesssensory perception

OR5P3 SCN11A OR10A7 TRPA1 OR10P1 ACP3 ANO1 OR6C65 OR10J1 OR51A7 SCN1A RP1L1 SCN8A SCN9A TAS2R30 OR13C7

7.64e-04107212516GO:0007600
GeneOntologyBiologicalProcessdetection of temperature stimulus involved in sensory perception

SCN11A ANO1 SCN9A

7.83e-04301253GO:0050961
GeneOntologyBiologicalProcesspositive regulation of insulin secretion

TRPA1 ANXA7 ANO1 ADCY8 HCFC1

8.25e-041201255GO:0032024
GeneOntologyBiologicalProcesscardiac endothelial cell differentiation

PBRM1 NOTCH1

9.96e-0481252GO:0003348
GeneOntologyBiologicalProcessregulation of photoreceptor cell differentiation

CASZ1 NOTCH1

9.96e-0481252GO:0046532
GeneOntologyBiologicalProcessmulticellular organismal response to stress

SCN11A TRPA1 OSM SCN3A SCN9A

1.03e-031261255GO:0033555
GeneOntologyBiologicalProcessdetection of temperature stimulus

SCN11A ANO1 SCN9A

1.04e-03331253GO:0016048
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

4.99e-10171266GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

1.80e-08291266GO:0034706
GeneOntologyCellularComponentaxon

SCN11A TRPA1 ESR1 VPS16 BCR ADCY8 NCDN ADRA2C ARHGEF7 SCN1A SCN2A SCN3A SCN8A SCN9A HCFC1 DYNC1H1

9.19e-0589112616GO:0030424
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A SCN8A

2.26e-04201263GO:0033268
GeneOntologyCellularComponentcell body

SCN11A PSD2 P2RY12 ESR1 SH3GL2 VPS16 ADCY8 NCDN ADRA2C ARHGEF7 SCN1A SCN3A SCN8A HCFC1 DYNC1H1

4.79e-0492912615GO:0044297
GeneOntologyCellularComponentneuronal cell body

SCN11A PSD2 ESR1 SH3GL2 VPS16 ADCY8 NCDN ADRA2C ARHGEF7 SCN1A SCN3A SCN8A HCFC1 DYNC1H1

5.16e-0483512614GO:0043025
GeneOntologyCellularComponentcation channel complex

AKAP6 SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

5.64e-042351267GO:0034703
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A SCN8A

6.97e-04291263GO:0043194
GeneOntologyCellularComponentSWI/SNF complex

ARID1B PBRM1 ACTL6B

7.71e-04301263GO:0016514
GeneOntologyCellularComponentcytoplasmic microtubule

CYP2A6 CYP2A13 FAM161B DYNC1H1 KIF2C

1.28e-031331265GO:0005881
GeneOntologyCellularComponentglutamatergic synapse

SCN11A PSD2 SH3GL2 ANO1 BCR ADCY8 NCDN ADRA2C SCN2A SCN8A PRICKLE2 NOTCH1 KIF2C

1.32e-0381712613GO:0098978
GeneOntologyCellularComponentT-tubule

AKAP6 ESR1 SCN1A SCN2A

1.33e-03791264GO:0030315
GeneOntologyCellularComponentbBAF complex

ARID1B ACTL6B

1.57e-03101262GO:0140092
HumanPhenoClonic seizure

PIGP PEX3 SCN1A SCN2A SCN3A SCN8A SCN9A

8.61e-0681487HP:0020221
HumanPhenoPes valgus

ANO1 WDR19 SCN1A SCN2A SCN9A SMG9

1.15e-0556486HP:0008081
HumanPhenoComplex febrile seizure

SCN1A SCN2A SCN8A SCN9A

1.16e-0516484HP:0011172
HumanPhenoGeneralized clonic seizure

PIGP SCN1A SCN2A SCN8A SCN9A

1.36e-0534485HP:0011169
HumanPhenoMultifocal epileptiform discharges

PIGP SCN1A SCN2A SCN8A SCN9A ACTL6B

3.01e-0566486HP:0010841
HumanPhenoFocal clonic seizure

PEX3 SCN1A SCN2A SCN8A SCN9A

3.93e-0542485HP:0002266
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN2A SCN9A

4.26e-058483HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN2A SCN9A

4.26e-058483HP:0200048
HumanPhenoFocal hemiclonic seizure

SCN1A SCN2A SCN8A SCN9A

7.59e-0525484HP:0006813
HumanPhenoAplastic/hypoplastic fingernail

CCDC22 PIGP BCR ARID1B SCN2A NOTCH1

1.03e-0482486HP:0008384
HumanPhenoSimple febrile seizure

SCN1A SCN2A SCN3A SCN8A

1.04e-0427484HP:0011171
HumanPhenoShort distal phalanx of finger

CCDC22 BCR WDR19 ARID1B GLI1 ACTL6B NOTCH1

1.06e-04119487HP:0009882
HumanPhenoLimited neck range of motion

SCN1A SCN2A SCN9A

1.23e-0411483HP:0000466
HumanPhenoAplasia/Hypoplasia of the distal phalanges of the hand

CCDC22 BCR WDR19 ARID1B GLI1 ACTL6B NOTCH1

1.37e-04124487HP:0009835
HumanPhenoCortical dysplasia

RTTN SCN1A SCN2A SCN9A DYNC1H1

1.60e-0456485HP:0002539
HumanPhenoEpilepsia partialis continua

SCN1A SCN2A SCN9A

1.63e-0412483HP:0012847
HumanPhenoFocal automatism seizure

SCN1A SCN2A SCN8A

1.63e-0412483HP:0032898
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN2A SCN9A

2.10e-0413483HP:0007058
HumanPhenoAbnormal fingernail morphology

CCDC22 PIGP BCR WDR19 ARID1B GLI1 SCN2A SCN9A NOTCH1

2.39e-04230489HP:0001231
HumanPhenoGlobal brain atrophy

PIGP VPS16 SCN1A SCN2A SCN9A SMG9 ACTL6B

2.68e-04138487HP:0002283
HumanPhenoGeneralized tonic seizure

PIGP SCN1A SCN2A SCN8A SCN9A

3.02e-0464485HP:0010818
HumanPhenoFacial tics

SCN1A SCN2A SCN9A

3.30e-0415483HP:0011468
HumanPhenoPhotosensitive tonic-clonic seizure

SCN1A SCN2A SCN9A

3.30e-0415483HP:0007207
HumanPhenoAnonychia

PIGP BCR ARID1B SCN2A NOTCH1

3.49e-0466485HP:0001798
HumanPhenoInfection-related seizure

PIGP SLC13A3 SCN1A SCN2A SCN3A SCN8A SCN9A

3.63e-04145487HP:0032892
HumanPhenoSeizure precipitated by febrile infection

PIGP SLC13A3 SCN1A SCN2A SCN3A SCN8A SCN9A

3.63e-04145487HP:0032894
HumanPhenoFebrile seizure (within the age range of 3 months to 6 years)

PIGP SLC13A3 SCN1A SCN2A SCN3A SCN8A SCN9A

3.63e-04145487HP:0002373
HumanPhenoDysgenesis of the hippocampus

SCN1A SCN2A SCN9A

4.04e-0416483HP:0025101
HumanPhenoImpulsivity

VPS16 SCN1A SCN2A SCN3A SCN8A SCN9A ACTL6B

4.28e-04149487HP:0100710
HumanPhenoShort phalanx of finger

CCDC22 PIGP BCR WDR19 ARID1B GLI1 SCN2A ACTL6B RERE NOTCH1

4.47e-043064810HP:0009803
HumanPhenoFocal motor status epilepticus

SCN1A SCN2A SCN9A

4.87e-0417483HP:0032663
HumanPhenoBifid ribs

CASZ1 PTCH2 RERE

4.87e-0417483HP:0000892
HumanPhenoAtypical absence status epilepticus

SCN1A SCN2A SCN9A

4.87e-0417483HP:0011151
HumanPhenoAbsent fingernail

PIGP BCR SCN2A NOTCH1

4.95e-0440484HP:0001817
HumanPhenoAplasia/Hypoplasia of the nails

CCDC22 PIGP BCR ARID1B GLI1 SCN2A ACTL6B RERE NOTCH1

5.61e-04258489HP:0008386
HumanPhenoVisually-induced seizure

SCN1A SCN2A SCN9A

5.80e-0418483HP:0020216
HumanPhenoGeneralized non-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

5.80e-0418483HP:0032860
HumanPhenoCompulsive behaviors

VPS16 BCR ARID1B SCN1A SCN2A SCN8A SCN9A

6.10e-04158487HP:0000722
HumanPhenoAplasia/Hypoplasia of the phalanges of the hand

CCDC22 PIGP BCR WDR19 ARID1B GLI1 SCN2A ACTL6B RERE NOTCH1

6.21e-043194810HP:0009767
HumanPhenoEEG with focal epileptiform discharges

PIGP SCN1A SCN2A SCN8A SCN9A ACTL6B

7.54e-04118486HP:0011185
HumanPhenoAbnormality of central nervous system electrophysiology

CCDC22 PIGP PEX3 RTTN CASZ1 ARID1B SCN1A SCN2A SCN3A SCN8A SCN9A SMG9 ACTL6B RERE HCFC1 NOTCH1

7.70e-047384816HP:0030178
HumanPhenoNon-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

8.00e-0420483HP:0032671
HumanPhenoNeonatal electro-clinical non-motor seizure

SCN2A SCN8A

8.54e-045482HP:0032812
HumanPhenoNeonatal seizure with electrographic correlate

SCN2A SCN8A

8.54e-045482HP:0032808
HumanPhenoNeonatal electro-clinical seizure

SCN2A SCN8A

8.54e-045482HP:0032809
HumanPhenoNeonatal electro-clinical seizure with behavior arrest

SCN2A SCN8A

8.54e-045482HP:0032823
HumanPhenoFocal head nodding automatism seizure

SCN2A SCN8A

8.54e-045482HP:0032906
HumanPhenoAllodynia

SCN11A SCN9A

8.54e-045482HP:0012533
HumanPhenoTalipes valgus

SCN1A SCN2A SCN9A

9.27e-0421483HP:0004684
HumanPhenoDysesthesia

SCN11A CHST14 SCN9A

9.27e-0421483HP:0012534
HumanPhenoDelayed myelination

PIGP NCDN ARID1B SCN1A SCN2A SMG9 ACTL6B RERE HCFC1

1.01e-03280489HP:0012448
HumanPhenoFocal impaired awareness seizure

SCN1A SCN2A SCN3A SCN8A SCN9A RERE

1.06e-03126486HP:0002384
HumanPhenoReflex seizure

SCN1A SCN2A SCN9A

1.07e-0322483HP:0020207
HumanPhenoAbnormal distal phalanx morphology of finger

CCDC22 BCR WDR19 ARID1B GLI1 ACTL6B NOTCH1

1.08e-03174487HP:0009832
DomainNa_channel_asu

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

1.34e-11101216IPR001696
DomainNa_trans_assoc

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

1.34e-11101216IPR010526
DomainNa_trans_assoc

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

1.34e-11101216PF06512
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN8A SCN9A

6.27e-1161215PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN8A SCN9A

6.27e-1161215IPR024583
DomainIQ

DCAF6 MYH7B SCN1A SCN2A SCN3A MYO1F SCN8A SCN9A

5.32e-08811218SM00015
DomainIQ_motif_EF-hand-BS

DCAF6 MYH7B SCN1A SCN2A SCN3A MYO1F SCN8A SCN9A

1.22e-07901218IPR000048
DomainIQ

DCAF6 MYH7B SCN1A SCN2A SCN3A MYO1F SCN8A SCN9A

1.58e-07931218PS50096
DomainChannel_four-helix_dom

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

1.81e-06571216IPR027359
Domain-

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

1.81e-065712161.20.120.350
DomainIon_trans_dom

SCN11A TRPA1 SCN1A SCN2A SCN3A SCN8A SCN9A

9.33e-061141217IPR005821
DomainIon_trans

SCN11A TRPA1 SCN1A SCN2A SCN3A SCN8A SCN9A

9.33e-061141217PF00520
DomainARM-type_fold

CAND2 UBQLN2 UBQLN1 RTTN MROH5 MEI1 NCDN NCAPD2 EFR3B PRKDC EIF4G3

1.29e-0533912111IPR016024
DomainUbiquilin-1/2

UBQLN2 UBQLN1

4.16e-0521212IPR028430
DomainIQ

SCN1A SCN3A MYO1F SCN8A SCN9A

9.72e-05711215PF00612
DomainCyt_P450_E_grp-I_CYP2A-like

CYP2A6 CYP2A13

2.48e-0441212IPR008067
DomainARM-like

CAND2 RTTN MROH5 MEI1 ARID1B NCAPD2 EFR3B PRKDC

3.78e-042701218IPR011989
DomainNa/sul_symport

SLC13A3 SLC13A2

4.11e-0451212IPR001898
DomainNa_sulph_symp

SLC13A3 SLC13A2

4.11e-0451212PF00939
DomainVWA_2

INTS6L INTS6

4.11e-0451212PF13519
DomainHEAT

CAND2 NCAPD2 PRKDC EIF4G3

5.43e-04581214IPR000357
Domain-

CAND2 RTTN MROH5 ARID1B NCAPD2 EFR3B PRKDC

6.12e-0422212171.25.10.10
DomainUbiquilin

UBQLN2 UBQLN1

6.14e-0461212IPR015496
DomainDH_1

ARHGEF28 BCR ARHGEF7 ARHGEF6

7.43e-04631214PS00741
DomainRhoGEF

ARHGEF28 BCR ARHGEF7 ARHGEF6

9.91e-04681214SM00325
DomainRhoGEF

ARHGEF28 BCR ARHGEF7 ARHGEF6

1.11e-03701214PF00621
DomainDH_2

ARHGEF28 BCR ARHGEF7 ARHGEF6

1.11e-03701214PS50010
DomainINT_SG_DDX_CT_C

INTS6L INTS6

1.14e-0381212PF15300
DomainINT_SG_DDX_CT_C

INTS6L INTS6

1.14e-0381212IPR029307
DomainDH-domain

ARHGEF28 BCR ARHGEF7 ARHGEF6

1.17e-03711214IPR000219
Domain-

ARHGEF28 BCR ARHGEF7 ARHGEF6

1.17e-037112141.20.900.10
DomainSTI1

UBQLN2 UBQLN1

1.81e-03101212SM00727
DomainSTI1_HS-bd

UBQLN2 UBQLN1

1.81e-03101212IPR006636
DomainGDS_CDC24_CS

BCR ARHGEF7 ARHGEF6

2.04e-03391213IPR001331
DomainBAH

PBRM1 RERE

2.20e-03111212SM00439
DomainBAH

PBRM1 RERE

2.20e-03111212PF01426
DomainBAH

PBRM1 RERE

2.20e-03111212PS51038
DomainBAH_dom

PBRM1 RERE

2.20e-03111212IPR001025
DomainAAA+_ATPase

DNAH3 ABCF1 ABCA8 ORC4 DYNC1H1

2.47e-031441215IPR003593
DomainAAA

DNAH3 ABCF1 ABCA8 ORC4 DYNC1H1

2.47e-031441215SM00382
DomainUBQ

UBQLN2 UBQLN1 OASL

2.71e-03431213SM00213
DomainCyt_P450_E_grp-I

CYP1A1 CYP2A6 CYP2A13

3.09e-03451213IPR002401
Domainubiquitin

UBQLN2 UBQLN1 OASL

3.49e-03471213PF00240
DomainDynein_heavy_chain_D4_dom

DNAH3 DYNC1H1

3.60e-03141212IPR024317
DomainDynein_HC_stalk

DNAH3 DYNC1H1

3.60e-03141212IPR024743
DomainDynein_heavy_dom-2

DNAH3 DYNC1H1

3.60e-03141212IPR013602
DomainDHC_N2

DNAH3 DYNC1H1

3.60e-03141212PF08393
DomainMT

DNAH3 DYNC1H1

3.60e-03141212PF12777
DomainAAA_8

DNAH3 DYNC1H1

3.60e-03141212PF12780
DomainATPase_dyneun-rel_AAA

DNAH3 DYNC1H1

3.60e-03141212IPR011704
DomainAAA_5

DNAH3 DYNC1H1

3.60e-03141212PF07728
DomainHEAT

CAND2 NCAPD2 PRKDC

3.71e-03481213PF02985
DomainDHC_fam

DNAH3 DYNC1H1

4.14e-03151212IPR026983
Domain-

ARID3A ARID1B

4.14e-031512121.10.150.60
DomainBRIGHT

ARID3A ARID1B

4.14e-03151212SM00501
DomainARID_dom

ARID3A ARID1B

4.14e-03151212IPR001606
DomainARID

ARID3A ARID1B

4.14e-03151212PS51011
DomainARID

ARID3A ARID1B

4.14e-03151212PF01388
DomainDynein_heavy_dom

DNAH3 DYNC1H1

4.14e-03151212IPR004273
DomainDynein_heavy

DNAH3 DYNC1H1

4.14e-03151212PF03028
DomainCyt_P450_CS

CYP1A1 CYP2A6 CYP2A13

4.91e-03531213IPR017972
DomainUBIQUITIN_2

UBQLN2 UBQLN1 OASL

5.17e-03541213PS50053
DomainCYTOCHROME_P450

CYP1A1 CYP2A6 CYP2A13

6.02e-03571213PS00086
Domain-

CYP1A1 CYP2A6 CYP2A13

6.32e-035812131.10.630.10
DomainUbiquitin_dom

UBQLN2 UBQLN1 OASL

6.32e-03581213IPR000626
Domainp450

CYP1A1 CYP2A6 CYP2A13

6.32e-03581213PF00067
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

5.13e-0831956M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

6.28e-0832956M27455
PathwayREACTOME_L1CAM_INTERACTIONS

SCN11A SH3GL2 SCN1A SCN2A SCN3A SCN8A SCN9A

1.71e-05121957M872
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN3A SCN8A

3.50e-0528954M45519
PathwayREACTOME_CARDIAC_CONDUCTION

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

2.43e-04130956M27454
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

SCN2A SCN3A SCN9A TAS2R30

2.77e-0447954M42524
PathwayWP_RETT_SYNDROME

SCN1A SCN2A SCN8A ACTL6B

3.00e-0448954M39759
PathwayWP_THYROID_HORMONES_PRODUCTION_AND_PERIPHERAL_DOWNSTREAM_SIGNALING_EFFECTS

ADCY8 MAP4K5 DIO3 ACTL6B NOTCH1

4.07e-0493955M39791
PathwayREACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS

SLC13A3 SLC13A2

4.43e-045952MM15099
PathwayREACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS

SLC13A3 SLC13A2

4.43e-045952M27354
PathwayKEGG_MEDICUS_ENV_FACTOR_NNK_TO_DNA_ADDUCTS

CYP2A6 CYP2A13

4.43e-045952M47808
PathwayREACTOME_XENOBIOTICS

CYP1A1 CYP2A6 CYP2A13

4.76e-0423953M5372
PathwayREACTOME_XENOBIOTICS

CYP1A1 CYP2A6 CYP2A13

6.12e-0425953MM14846
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

1.84e-139128616382098
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN3A SCN8A SCN9A

3.73e-126128523652591
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A SCN8A

1.75e-104128417537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A SCN8A

1.75e-104128435031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A SCN8A

1.75e-104128429578003
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN3A SCN8A SCN9A

7.84e-1013128515123669
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN3A SCN9A

8.73e-10512848812438
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN11A SCN3A SCN8A SCN9A

8.73e-105128422875929
Pubmed

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.

SCN11A TRPA1 SCN3A SCN8A

2.61e-096128423711479
Pubmed

Significant determinants of mouse pain behaviour.

SCN11A TRPA1 SCN3A SCN9A

1.21e-088128425101983
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A SCN8A

2.17e-089128415746173
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN3A SCN9A

4.87e-083128319284629
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A SCN9A

4.87e-083128333895391
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

4.87e-083128323859570
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

4.87e-083128312610651
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

4.87e-083128318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

4.87e-083128317544618
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A SCN8A

4.87e-083128332845893
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A SCN8A

4.87e-083128328518218
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A SCN8A

4.87e-083128317928448
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

4.87e-083128314973256
Pubmed

Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia.

SCN11A SCN8A SCN9A

4.87e-083128315302875
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A SCN8A

8.47e-0812128430175250
Pubmed

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.

ARID1B SCN1A SCN2A

1.94e-074128326637798
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

1.94e-074128335801810
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A SCN8A

1.94e-074128321156207
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

1.94e-07412838974318
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A SCN3A

4.84e-07512831679748
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

4.84e-075128324337656
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN3A SCN8A

4.84e-075128317724025
Pubmed

Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.

SCN11A SCN8A SCN9A

9.66e-076128316029194
Pubmed

Are voltage-dependent ion channels involved in the endothelial cell control of vasomotor tone?

SCN11A SCN2A SCN8A

9.66e-076128317513486
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A SCN8A

1.69e-067128325818041
Pubmed

Transport of Iodothyronines by Human L-Type Amino Acid Transporters.

SLC43A2 SLC43A1 DIO3

1.69e-067128326305885
Pubmed

Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development.

ESR1 ARID1B PBRM1

1.69e-067128321445275
Pubmed

Pain without nociceptors? Nav1.7-independent pain mechanisms.

SCN11A SCN3A SCN9A

1.69e-067128324440715
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A SCN3A

1.05e-051212838169823
Pubmed

OSM is overexpressed in knee osteoarthritis and Notch signaling is involved in the effects of OSM on MC3T3-E1 cell proliferation and differentiation.

OSM NOTCH1

1.34e-052128225845347
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

1.34e-052128220346423
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

1.34e-052128237901435
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

1.34e-052128226410685
Pubmed

Suppressed hepatocyte proliferation via a ROS-HNE-P21 pathway is associated with nicotine- and cotinine-enhanced alcoholic fatty liver in mice.

CYP2A6 CYP2A13

1.34e-052128230876690
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

1.34e-052128210827969
Pubmed

CYP2A5 induction and hepatocellular stress: an adaptive response to perturbations of heme homeostasis.

CYP2A6 CYP2A13

1.34e-052128221395539
Pubmed

Species differences in coumarin metabolism: a molecular modelling evaluation of CYP2A interactions.

CYP2A6 CYP2A13

1.34e-052128212162851
Pubmed

Molecular characterization of the murine Coh locus: an amino acid difference at position 117 confers high and low coumarin 7-hydroxylase activity in P450coh.

CYP2A6 CYP2A13

1.34e-05212821302041
Pubmed

Structural alteration of mouse P450coh by mutation of glycine-207 to proline: spin equilibrium, enzyme kinetics, and heat sensitivity.

CYP2A6 CYP2A13

1.34e-05212828395817
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

1.34e-052128219694741
Pubmed

Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.

SCN2A SCN8A

1.34e-052128235348308
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

1.34e-052128211245985
Pubmed

Absence of cytochrome P450 2A5 enhances alcohol-induced liver injury in mice.

CYP2A6 CYP2A13

1.34e-052128225804444
Pubmed

Effect of pyrazole, cobalt and phenobarbital on mouse liver cytochrome P-450 2a-4/5 (Cyp2a-4/5) expression.

CYP2A6 CYP2A13

1.34e-05212821520280
Pubmed

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.

SCN2A SCN8A

1.34e-052128215760941
Pubmed

Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model.

CYP2A6 CYP2A13

1.34e-052128223917075
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

1.34e-05212821317301
Pubmed

Genomic Landscape of Experimental Bladder Cancer in Rodents and Its Application to Human Bladder Cancer: Gene Amplification and Potential Overexpression of Cyp2a5/CYP2A6 Are Associated with the Invasive Phenotype.

CYP2A6 CYP2A13

1.34e-052128227902773
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

1.34e-052128223016767
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

1.34e-052128227153334
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

1.34e-052128224990319
Pubmed

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

SCN3A SCN9A

1.34e-052128225172946
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

1.34e-052128231439038
Pubmed

A new Drosophila model of Ubiquilin knockdown shows the effect of impaired proteostasis on locomotive and learning abilities.

UBQLN2 UBQLN1

1.34e-052128229247619
Pubmed

Circadian Regulation of Hepatic Cytochrome P450 2a5 by Peroxisome Proliferator-Activated Receptor γ.

CYP2A6 CYP2A13

1.34e-052128230154104
Pubmed

Towards a molecular understanding of the overlapping and distinct roles of UBQLN1 and UBQLN2 in lung cancer progression and metastasis.

UBQLN2 UBQLN1

1.34e-052128235063704
Pubmed

Joint effects of the CYP1A1 MspI, ERalpha PvuII, and ERalpha XbaI polymorphisms on the risk of breast cancer: results from a population-based case-control study in Shanghai, China.

CYP1A1 ESR1

1.34e-052128216492926
Pubmed

Mechanism-based inhibition of cytochrome P450 (CYP)2A6 by chalepensin in recombinant systems, in human liver microsomes and in mice in vivo.

CYP2A6 CYP2A13

1.34e-052128221418183
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

1.34e-052128231943325
Pubmed

Human CYP2A6 is induced by estrogen via estrogen receptor.

CYP2A6 ESR1

1.34e-052128217646279
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

1.34e-052128215249644
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

1.34e-052128227690330
Pubmed

Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model.

CYP2A6 CYP2A13

1.34e-052128219923441
Pubmed

Effects of lipopolysaccharide-stimulated inflammation and pyrazole-mediated hepatocellular injury on mouse hepatic Cyp2a5 expression.

CYP2A6 CYP2A13

1.34e-052128212499123
Pubmed

Sodium channel slow inactivation interferes with open channel block.

SCN8A SCN9A

1.34e-052128227174182
Pubmed

Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.

SCN2A SCN8A

1.34e-052128218601978
Pubmed

Function and regulation of the Cyp2a5/CYP2A6 genes in response to toxic insults in the liver.

CYP2A6 CYP2A13

1.34e-052128222497566
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

1.34e-052128223965409
Pubmed

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.

SCN2A SCN8A

1.34e-052128219465131
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

1.34e-052128230693367
Pubmed

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

SCN2A SCN8A

1.34e-052128223735284
Pubmed

The role of CYP2A5 in liver injury and fibrosis: chemical-specific difference.

CYP2A6 CYP2A13

1.34e-052128226363552
Pubmed

Mouse liver P450Coh: genetic regulation of the pyrazole-inducible enzyme and comparison with other P450 isoenzymes.

CYP2A6 CYP2A13

1.34e-05212822712571
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

1.34e-052128229649454
Pubmed

Evaluation of inhibition selectivity for human cytochrome P450 2A enzymes.

CYP2A6 CYP2A13

1.34e-052128222696418
Pubmed

Nicotine enhances alcoholic fatty liver in mice: Role of CYP2A5.

CYP2A6 CYP2A13

1.34e-052128230222954
Pubmed

Up-regulation of CYP2A5 expression by porphyrinogenic agents in mouse liver.

CYP2A6 CYP2A13

1.34e-05212827543189
Pubmed

Expression of Gli1 correlates with the transition of breast cancer cells to estrogen-independent growth.

ESR1 GLI1

1.34e-052128219191023
Pubmed

Cytochrome P2A13 and P1A1 gene polymorphisms are associated with the occurrence of uterine leiomyoma.

CYP1A1 CYP2A13

1.34e-052128216835796
Pubmed

Lung cancer risk in relation to nicotinic acetylcholine receptor, CYP2A6 and CYP1A1 genotypes in the Bangladeshi population.

CYP1A1 CYP2A6

1.34e-052128223178447
Pubmed

Characterization and regulation of sex-specific mouse steroid hydroxylase genes.

CYP2A6 CYP2A13

1.34e-05212822372744
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

1.34e-052128233096315
Pubmed

Interaction of the double-strand break repair kinase DNA-PK and estrogen receptor-alpha.

ESR1 PRKDC

1.34e-052128220219974
Pubmed

Metabolic effects of CYP2A6 and CYP2A13 on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced gene mutation--a mammalian cell-based mutagenesis approach.

CYP2A6 CYP2A13

1.34e-052128221473878
Pubmed

The CYP2A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis.

CYP2A6 CYP2A13

1.34e-05212827581481
Pubmed

Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver.

CYP2A6 CYP2A13

1.34e-052128228298240
Pubmed

Sodium channel expression within chronic multiple sclerosis plaques.

SCN2A SCN8A

1.34e-052128217805013
Pubmed

Genetic polymorphisms for a phenobarbital-inducible cytochrome P-450 map to the Coh locus in mice.

CYP2A6 CYP2A13

1.34e-05212826309775
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

1.34e-052128226311622
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

1.34e-052128233411788
Pubmed

Role of CYP2A5 in the bioactivation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.

CYP2A6 CYP2A13

1.34e-052128222262919
Pubmed

Modulation of cytochrome P450 2A5 activity by lipopolysaccharide: low-dose effects and non-monotonic dose-response relationship.

CYP2A6 CYP2A13

1.34e-052128225635819
InteractionTMEM108 interactions

CAND2 ECHDC1 ANXA7 SH3GL2 ARHGEF6

7.34e-07311125int:TMEM108
InteractionSCN11A interactions

SCN11A SCN1A SCN8A SCN9A

1.18e-06151124int:SCN11A
InteractionSCN4B interactions

SCN1A SCN2A SCN8A

9.17e-0681123int:SCN4B
Cytoband2q24

SCN3A SCN9A

4.17e-041112822q24
CytobandEnsembl 112 genes in cytogenetic band chr2q24

SCN1A SCN2A SCN3A SCN9A

4.57e-041271284chr2q24
Cytoband12q13.2

OR10A7 OR10P1 OR6C65

5.00e-0455128312q13.2
Cytoband2q24.3

SCN1A SCN2A

9.02e-041612822q24.3
GeneFamilySodium voltage-gated channel alpha subunits

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

1.22e-1299261203
GeneFamilyUbiquilin family

UBQLN2 UBQLN1

2.54e-045922783
CoexpressionGSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_DN

DCAF6 MAN2A2 MEI1 TEK PLXDC2 ARHGEF7 PRICKLE2 NOTCH1

6.53e-062001288M8007
DrugZonisamide

SCN11A SCN1A SCN2A SCN3A SCN9A

2.70e-08171255DB00909
Drugbenzyl selenocyanate

CYP1A1 CYP2A6 CYP2A13

1.60e-0651253ctd:C054108
Drugdiphenyl

CYP1A1 CYP2A13 ESR1

1.60e-0651253ctd:C010574
DrugN-methyl-N-2-(methylsulfinyl)ethylpropionic acid amide

CYP1A1 CYP2A6 CYP2A13

1.60e-0651253ctd:C062567
DrugTetrodotoxin

CYP1A1 SCN2A SCN3A SCN8A SCN9A

2.60e-06401255ctd:D013779
DrugAPETx1, Anthopleura elegantissima

SCN2A SCN3A SCN8A

3.19e-0661253ctd:C475726
Drugfenpropathrin

CYP1A1 SCN2A SCN3A

3.19e-0661253ctd:C044267
DrugN'-nitrosoanabasine

CYP1A1 CYP2A6 CYP2A13

3.19e-0661253ctd:C010257
Drugcarbamazepine

CYP2A6 ESR1 SLC13A3 SLC13A2 ADCY8 SCN2A SCN3A SCN9A

6.71e-061791258CID000002554
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN2A SCN3A SCN8A

8.87e-0681253ctd:C489827
DrugN-nitrosoguvacoline

CYP1A1 CYP2A6 CYP2A13

1.32e-0591253CID000062103
Drug3-(methylnitrosamino)propionaldehyde

CYP1A1 CYP2A6 CYP2A13

1.32e-0591253CID000098533
Drugacenaphthylene

CYP1A1 CYP2A6 CYP2A13

1.32e-0591253ctd:C042553
Drugdecamethrin

CYP1A1 CYP2A6 ESR1 SCN1A SCN2A SCN3A SCN8A

1.64e-051461257ctd:C017180
Drugcyfluthrin

ESR1 BCR SCN2A SCN3A

1.85e-05291254ctd:C052570
Drugpropargyl ether

CYP2A6 CYP2A13

2.99e-0521252ctd:C531209
DrugHempa

CYP2A6 CYP2A13

2.99e-0521252ctd:D006492
Drugnicotine imine

CYP2A6 CYP2A13

2.99e-0521252ctd:C034629
Drugalpha-nicotyrine

CYP2A6 CYP2A13

2.99e-0521252ctd:C008615
Drugpoly(maleic acid

SLC13A3 SLC13A2

2.99e-0521252CID000011848
DrugN-nitrosoguvacoline

CYP2A6 CYP2A13

2.99e-0521252ctd:C036676
Drugd 6-20

CYP1A1 CYP2A6 CYP2A13

4.44e-05131253CID000161569
DrugSkatole

CYP1A1 CYP2A6 CYP2A13

4.44e-05131253ctd:D012862
Drugalizarin

CYP1A1 CYP2A6 ESR1

4.44e-05131253ctd:C010078
DrugMnPN

CYP1A1 CYP2A6 CYP2A13

5.63e-05141253CID000062163
Drugquinalphos

CYP1A1 ESR1 ACP3

5.63e-05141253CID000026124
DrugN'-nitrosonornicotine

CYP1A1 CYP2A6 CYP2A13

7.00e-05151253ctd:C008655
DrugHCFC-141b

CYP1A1 CYP2A6 HCFC1

8.59e-05161253CID000015586
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN3A SCN9A

8.94e-0531252ctd:C561228
Drugn-propyl disulfide

CYP1A1 CYP2A6

8.94e-0531252ctd:C041288
Drug2'-methoxyacetophenone

CYP2A6 CYP2A13

8.94e-0531252CID000068481
Drugdipropyl sulfide

CYP1A1 CYP2A6

8.94e-0531252ctd:C087894
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

7.85e-13101196DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

7.85e-13101196DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN1A SCN2A SCN3A SCN8A SCN9A

3.43e-12121196DOID:0060170 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN11A SLC13A3 SLC13A2 SCN1A SCN2A SCN3A SCN8A SCN9A PRICKLE2 DYNC1H1

1.27e-0916311910DOID:1826 (implicated_via_orthology)
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN9A

1.74e-06221194DOID:2030 (implicated_via_orthology)
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A SCN9A

5.28e-0691193C3502809
DiseaseEarly Infantile Epileptic Encephalopathy 6

SCN1A SCN9A

1.61e-0521192C4551549
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A SCN9A

1.78e-05131193C0751122
DiseaseNeoplasm of uncertain or unknown behavior of breast

ESR1 ARID1B PBRM1 NOTCH1

2.27e-05411194C0496956
DiseaseBreast adenocarcinoma

ESR1 ARID1B PBRM1 NOTCH1

2.27e-05411194C0858252
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

PIGP SCN1A SCN2A

3.45e-05161193C0393706
Diseaseamyotrophic lateral sclerosis type 15 (implicated_via_orthology)

UBQLN2 UBQLN1

4.83e-0531192DOID:0060206 (implicated_via_orthology)
DiseaseB Virus Infection

SCN8A SCN9A

4.83e-0531192C0037140
DiseaseBenign familial infantile epilepsy

SCN2A SCN8A

4.83e-0531192cv:C5575231
DiseasePostherpetic neuralgia

SCN8A SCN9A

4.83e-0531192C0032768
DiseaseHerpesviridae Infections

SCN8A SCN9A

4.83e-0531192C0019372
DiseasePrimary Erythermalgia

SCN11A SCN9A

4.83e-0531192C0014805
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN11A SCN9A

4.83e-0531192C1833661
Diseasecaffeine metabolite measurement

CYP1A1 CYP2A6 MAP4K5

5.91e-05191193EFO_0007872
DiseaseEpilepsy

ARID1B SCN1A SCN2A SCN8A SCN9A

8.20e-051091195C0014544
DiseaseIntellectual Disability

AKAP6 PIGP RTTN SCN1A SCN3A SCN8A TRAPPC4 ACTL6B DYNC1H1

8.62e-054471199C3714756
DiseaseX-21286 measurement

CYP1A1 CYP2A6

9.63e-0541192EFO_0800804
Diseasealcohol use disorder (implicated_via_orthology)

PSD2 ARID1B PBRM1 MAP4K5 ACTL6B NOTCH1

1.44e-041951196DOID:1574 (implicated_via_orthology)
Diseasescavenger receptor class F member 1 measurement

SLC43A2 PRPF8

1.60e-0451192EFO_0008276
Diseasechordin-like protein 1 measurement

ARHGEF7 RTL9

1.60e-0451192EFO_0020257
DiseaseCortical visual impairment

PIGP TRAPPC4

1.60e-0451192C4048268
DiseaseVisual Cortex Disorder

PIGP TRAPPC4

1.60e-0451192C0234398
DiseaseKohlschutter-Tonz syndrome (implicated_via_orthology)

SLC13A3 SLC13A2

1.60e-0451192DOID:0111668 (implicated_via_orthology)
DiseaseFamilial benign neonatal epilepsy

SCN2A SCN8A

2.39e-0461192C0220669
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

3.34e-0471192C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

3.34e-0471192C0751057
DiseaseCongenital Pain Insensitivity

SCN11A SCN9A

3.34e-0471192C0002768
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN11A SCN9A

3.34e-0471192C0020075
Diseaseable to hear with hearing aids

CYP1A1 ARHGEF28

3.34e-0471192EFO_0009720
DiseaseEpilepsy, Cryptogenic

ARID1B SCN1A SCN2A SCN8A

3.45e-04821194C0086237
DiseaseAwakening Epilepsy

ARID1B SCN1A SCN2A SCN8A

3.45e-04821194C0751111
DiseaseAura

ARID1B SCN1A SCN2A SCN8A

3.45e-04821194C0236018
Diseaseserine measurement

MAP4K5 SCN3A DYNC1H1

3.81e-04351193EFO_0009774
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A SCN9A

4.44e-0481192C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A SCN9A

4.44e-0481192C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A SCN9A

4.44e-0481192C0338479
Diseasealcohol-related neurodevelopmental disorder (implicated_via_orthology)

SLC13A3 SLC13A2

4.44e-0481192DOID:0050667 (implicated_via_orthology)
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A SCN9A

4.44e-0481192C0751120
DiseaseScoliosis, unspecified

TRAPPC4 NOTCH1

4.44e-0481192C0036439
DiseaseMyoclonic Encephalopathy

SCN1A SCN9A

4.44e-0481192C0438414
DiseaseMyoclonic Absence Epilepsy

SCN1A SCN9A

4.44e-0481192C0393703
DiseaseNeurodevelopmental Disorders

ARID1B SCN1A SCN2A SCN8A

5.57e-04931194C1535926
DiseaseFebrile Convulsions

SCN1A SCN2A

5.70e-0491192C0009952
DiseaseMyoclonic Epilepsy

SCN1A SCN9A

5.70e-0491192C0014550
Diseasebitter beverage consumption measurement

CYP1A1 CYP2A6 MAP4K5

6.55e-04421193EFO_0010089
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A SCN9A

7.11e-04101192C0917800
Diseaseblood phosphate measurement

CYP1A1 TIGAR ESR1 BCAS1 EIF4G3

7.15e-041741195EFO_0010972
Diseasecoffee consumption measurement, tea consumption measurement

CYP1A1 CYP2A6 MAP4K5

7.51e-04441193EFO_0006781, EFO_0010091
Diseasesodium measurement

CYP1A1 CYP2A6 MAP4K5 SCN2A

8.17e-041031194EFO_0009282
Diseaseearly infantile epileptic encephalopathy (implicated_via_orthology)

IDH3B SCN8A

8.66e-04111192DOID:0050709 (implicated_via_orthology)
DiseaseMyoclonic Astatic Epilepsy

SCN1A SCN9A

8.66e-04111192C0393702
DiseaseProstatic Neoplasms

CYP1A1 CYP2A6 DCAF6 PIGP CHST14 ESR1 BCAS1 CASZ1 PRKDC

8.98e-046161199C0033578
DiseaseMalignant neoplasm of prostate

CYP1A1 CYP2A6 DCAF6 PIGP CHST14 ESR1 BCAS1 CASZ1 PRKDC

8.98e-046161199C0376358
Diseasecannabis dependence measurement

MEI1 SEMA3D SCN9A

9.69e-04481193EFO_0008457
Diseaseparaxanthine measurement

CYP1A1 CYP2A6

1.04e-03121192EFO_0021178
Diseasefrontotemporal dementia (implicated_via_orthology)

UBQLN2 UBQLN1

1.04e-03121192DOID:9255 (implicated_via_orthology)
Diseasegallbladder cancer (is_implicated_in)

CYP1A1 GLI1

1.22e-03131192DOID:3121 (is_implicated_in)
Diseasefactor VII measurement

MYH7B MAP4K5 SCN2A

1.44e-03551193EFO_0004619
DiseaseMMR-related febrile seizures

SCN1A SCN2A

1.64e-03151192EFO_0006519
Diseaseglucose homeostasis measurement, glucose effectiveness measurement

MYH7B MAP4K5

1.64e-03151192EFO_0006833, EFO_0006896
Diseasecoffee consumption, cups of coffee per day measurement

CYP1A1 MAP4K5

1.87e-03161192EFO_0004330, EFO_0006782
Diseaseprotein C measurement

MYH7B MAP4K5

2.11e-03171192EFO_0004633
Diseasesusceptibility to cold sores measurement

ABCF1 ANO1 TNXB

2.33e-03651193EFO_0008402
DiseaseFeeding difficulties

PIGP TRAPPC4

2.37e-03181192C0232466
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

2.37e-03181192HP_0002373
DiseaseMalignant neoplasm of liver

ESR1 ANXA7 PRICKLE2 HCFC1

2.66e-031421194C0345904
DiseaseLiver neoplasms

ESR1 ANXA7 PRICKLE2 HCFC1

2.66e-031421194C0023903
Diseasebreast size

ESR1 SERPINA2 MAP4K5

2.76e-03691193EFO_0004884
Diseaseneurodegenerative disease (implicated_via_orthology)

UBQLN2 UBQLN1 PTCH2 DYNC1H1

2.87e-031451194DOID:1289 (implicated_via_orthology)
Diseasecerebellum white matter volume change measurement, age at assessment

ABCA8 SMLR1

2.92e-03201192EFO_0008007, EFO_0021498
DiseaseContact Dermatitis

CYP1A1 OSM KIF2C

2.99e-03711193C0011616
DiseaseContact hypersensitivity

CYP1A1 OSM KIF2C

2.99e-03711193C0162351
Diseasechronic myeloid leukemia (is_implicated_in)

CYP1A1 BCR

3.22e-03211192DOID:8552 (is_implicated_in)
Diseaseprothrombin time measurement

PLXDC2 MAP4K5

3.22e-03211192EFO_0008390
DiseaseBipolar Disorder

ESR1 BCR ADCY8 ADRA2C PBRM1 SCN2A SCN8A

3.27e-034771197C0005586
DiseaseC-reactive protein measurement

AKAP6 CYP2A6 ARHGEF28 SERPINA2 OR10J1 ADCY8 MAP4K5 RP1L1 OASL RERE QSER1 EIF4G3

3.51e-03120611912EFO_0004458
Diseaseplatelet component distribution width

CYP1A1 SCN11A TCP11L1 RTTN RHCE ZNF490 SLC35B4 ANKRD28 TNXB

3.56e-037551199EFO_0007984
Diseaseautism spectrum disorder

SERPINA2 ADCY8 RP1L1 ARHGEF6

3.73e-031561194EFO_0003756
Diseasewaist-hip ratio

CAND2 SLC43A1 SLC13A3 ADCY8 SEMA3D OSM PBRM1 SCN2A EFR3B ANKRD28 RERE SCAI

4.00e-03122611912EFO_0004343

Protein segments in the cluster

PeptideGeneStartEntry
SLLPSSRVMPMTIQF

ADCY8

731

P40145
SLARALFMEPTLLML

ABCF1

461

Q8NE71
LMLFSNVLIMLSASP

ARHGEF6

471

Q15052
NVLIMLSASPRMSGF

ARHGEF6

476

Q15052
LLRMMLGIFQFTSTS

CYP2A6

201

P11509
QESLLLLMSPSMAFR

BCR

821

P11274
LLMSPSMAFRVHSRN

BCR

826

P11274
MMARLAAAALKPSAT

CASZ1

876

Q86V15
PSMRLKLIASNSTME

ACTL6B

371

O94805
ATLVMPFSLANELMA

ADRA2C

101

P18825
ISTMILPFMATSQLQ

GPR33

76

Q49SQ1
SRTSVLPAQMMALTF

ADGRG2

616

Q8IZP9
LALILATMMPVSSSS

ANKRD28

976

O15084
NVLLMLSASPRMSGF

ARHGEF7

506

Q14155
TLNQLLTSPSPMMRS

ARID1B

501

Q8NFD5
MILATRSFPQLRATM

ANXA7

366

P20073
TRNTITVPASFMLRM

DCAF6

816

Q58WW2
TVPASFMLRMLASLN

DCAF6

821

Q58WW2
LLPLAMSARFRLAMS

CCDC22

56

O60826
GVFVLTPSLAMMNIR

GKN3P

11

P0CG01
MNPARSALALLAMAQ

QSER1

1036

Q2KHR3
MLFPISMSATEFLLA

CYP1A1

1

P04798
MPILLFLIDTSASMN

INTS6L

1

Q5JSJ4
MPILLFLIDTSASMN

INTS6

1

Q9UL03
MPNMTSIREFILLGF

OR6C65

1

A6NJZ3
RTFSFLMNRMTSPRN

ARHGEF28

621

Q8N1W1
MLLMLALNRVTASHP

ORC4

281

O43929
MVSNPATRMLKTAAA

HCFC1

601

P51610
EMQALASTLLFIMFP

OR10A7

196

Q8NGE5
ASMVQTSLAMRLPFC

OR13C7

156

P0DN81
EMAKSSLRMRTPSNL

PBRM1

291

Q86U86
QMMSYQGLPSTRLAT

NOTCH1

2361

P46531
LTLMPLAMLSSSALF

GPR61

91

Q9BZJ8
CFTSLMNTLMTSLPA

NCDN

541

Q9UBB6
MTMRSLLRTPFLCGL

MCFD2

1

Q8NI22
SAIAISRTPVLMNFM

GHITM

141

Q9H3K2
MQNTLTRFMRLPLIS

ECHDC1

136

Q9NTX5
PPFMARMSAFQRLVT

DIO3

171

P55073
MTFTSLTLPNMFGDL

SLC43A2

161

Q8N370
SVSSIRQLMPFFMTL

DOP1B

2236

Q9Y3R5
LPNMFGNLRSTLMAL

SLC43A1

156

O75387
MPAVFMLASSSALQC

EXOC3-AS1

1

Q8N2X6
RTLMLLAQMSRISPS

IFNA1;

36

P01562
LAQMSRISPSSCLMD

IFNA1;

41

P01562
FQLLLLHPSATAMMD

MYH7B

31

A7E2Y1
PFSEASMMGLLTNLA

ESR1

336

P03372
MGLSLSSLPTMLRVF

OR51A7

71

Q8NH64
SSLPTMLRVFLFNAM

OR51A7

76

Q8NH64
NMTVLSMLPTLREAL

PEX3

66

P56589
NMMSALPSNFLDRLL

EFR3B

446

Q9Y2G0
RALDMLQMASSPIAS

FAM161B

321

Q96MY7
PNMAVGNMSVLLRSL

GLI1

1081

P08151
RISMAAALAMNSSPS

ANO1

541

Q5XXA6
FMFLLSLPNMILTNR

P2RY12

151

Q9H244
ELCNMPSMRGSLATL

MEI1

141

Q5TIA1
MALMQELYSTPASRL

OASL

1

Q15646
RTLMSAMTNLAALFP

ACP3

111

P15309
PLSLQMDMLSLSSQT

PRICKLE2

371

Q7Z3G6
MDMLSLSSQTPSLNR

PRICKLE2

376

Q7Z3G6
VLVTPTSVAMAFRML

SERPINA2

76

P20848
MLFLSMNLTISAGPA

FCAMR

161

Q8WWV6
MALLFPLLAALVMTS

IFNW1

1

P05000
NPTAMLLSASNMLRH

IDH3B

321

O43837
LLRMMLGSFQFTATS

CYP2A13

201

Q16696
VQTSPIHLAFSMMRL

DNAH3

1906

Q8TD57
AARTPATLFAVMFAM

ATL2

471

Q8NHH9
PSERSVMQAQSLMLL

C1QTNF8

196

P60827
TMPYLLRRANLTSML

MAN2A2

296

P49641
LSPVAFRGATMQMLK

DONSON

436

Q9NYP3
KTMTLFSALRALPDM

DYNC1H1

2601

Q14204
RMLPRNCQMLLFSAT

DDX19A

261

Q9NUU7
ESKPRTSLMAFLRQM

BCAS1

436

O75363
MLTFIMVARLATLCP

CAND2

1126

O75155
VMLPCTLATSLAFML

SLC13A2

501

Q13183
ASTAMMLPIANAILK

SLC13A3

146

Q8WWT9
QMSSPTFLRALMTAV

EIF4G3

1456

O43432
MAMDSSLQARLFPGL

KIF2C

1

Q99661
LLFGINMMSTSPLDS

PIGP

96

P57054
LHPMRALFLMSKSNF

MAP4K5

221

Q9Y4K4
RMLSSLVGMSQPISL

OR10J1

91

P30954
TRENTLMFMHLSPIL

MT-ND4

431

P03905
LRYSTLLSPRACMAM

OR10P1

131

Q8NGE3
SFLTATLMLMGAVSR

MROH5

421

Q6ZUA9
IRNLMAFATASMAQP

RPP25

46

Q9BUL9
MSIPLHSLRFNNTMR

RTL9

1

Q8NET4
MSTALFLLSLDMPIS

RTTN

501

Q86VV8
NMTLTMLANFVPLTL

TAS2R30

176

P59541
MANFAISSIRPHLMQ

TCP11L1

226

Q9NUJ3
LMSVTPNTGMSLFII

TIGAR

226

Q9NQ88
LNIAMPLHMIFRSGS

SLC35B4

86

Q969S0
PLHMIFRSGSLIANM

SLC35B4

91

Q969S0
ALTFALLMSARMGIF

SLC35B4

166

Q969S0
PRLTSNEKLMLASMF

TRAPPC4

101

Q9Y296
STLTAFLMMGNLSPV

LINC00869

56

P0C866
SINNMAAFLMAALVP

PTCH2

506

Q9Y6C5
STTLMMFLARVPFLF

SLC46A3

346

Q7Z3Q1
RMLTATQYIAPLMAN

PLXDC2

191

Q6UX71
RTLLFALMMSLPALF

SCN9A

1631

Q15858
SKLRSQVMSMARPQL

SMG9

471

Q9H0W8
LKNSAFSFAAMLMRP

WDR19

1206

Q8NEZ3
IRTLLFALMMSLPAL

SCN3A

1641

Q9NY46
MASLTSDPLARLQMF

RERE

1406

Q9P2R6
MLMSFLRKETSLPVA

OR5P3

81

Q8WZ94
LSLVLALLFPSMASM

OSM

11

P13725
IRTLLFALMMSLPAL

SCN1A

1656

P35498
ARSQDFHLFPALMML

SEMA3D

11

O95025
LAMSSVLSAFMRELP

SMLR1

36

H3BR10
LSLLSPFAFMLGMAQ

ABCA8

361

O94911
MLTMSVTLSPLRSQD

AKAP6

1

Q13023
MLRGISQLPAVATMS

ADAMDEC1

1

O15204
NFLAMAAQLPMSIRI

ARID3A

481

Q99856
LPSMLMFAVIVASSG

CHST14

41

Q8NCH0
AMLPTFLLMNLLSLA

NCAPD2

916

Q15021
TLPMMSTLYRLANQL

PRPF8

231

Q6P2Q9
PLLSIIQTFSMMLGD

TRPA1

901

O75762
MRRNSSLSFQMERPL

ZNF490

1

Q9ULM2
FSIRLATMSAMSVLI

RHCE

111

P18577
VIFVAMLGMLSPSSR

TM9SF4

361

Q92544
PGRVSASTQIMRALM

RP1L1

1076

Q8IWN7
SENVLSRLSLMAMPN

PSD2

231

Q9BQI7
NPASRAKLSMINTMS

SH3GL2

61

Q99962
LSAMSNPRAMQALLQ

UBQLN1

451

Q9UMX0
PDISLAMLSASIMYA

SERINC4

336

A6NH21
FMTLRNQPMALSLYR

VPS16

591

Q9H269
MMPAQYALTSSLVLL

TNXB

1

P22105
IRTLLFALMMSLPAL

SCN2A

1646

Q99250
NPLMAFLFVSGLSSM

SCAI

481

Q8N9R8
GIRTLLFALMMSLPA

SCN8A

1636

Q9UQD0
MKMRQQASFLPATLT

TEK

116

Q02763
SLATNFLLEMTSMSP

PRKDC

2556

P78527
VRIMMTSSLGLSFLL

TMEM225

66

Q6GV28
TMFCTTNSLPMDLLL

ZBED5

26

Q49AG3
LLFALMMSLPSLFNI

SCN11A

1486

Q9UI33
LSLLMTNLFPGMSVE

TTC16

476

Q8NEE8
DTLSAMSNPRAMQAL

UBQLN2

441

Q9UHD9
RQFPKQSLMLMATSN

TRBV20-1

51

A0A075B6N2
SFLMSSLLRKVMLPE

NLRP14

286

Q86W24
LMQTSEQAFLRMLFP

MYO1F

531

O00160