Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC39A10 SLC39A12 SLC20A1 SLC20A2 SLC2A13 SLC39A5	3.52e-05	119	103	6	GO:0015294
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC39A10 SLC39A12 SLC39A5	3.67e-05	13	103	3	GO:0140410
GeneOntologyMolecularFunction	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	DPYSL2 CAD CRMP1	7.11e-05	16	103	3	GO:0016812
GeneOntologyMolecularFunction	symporter activity	SLC39A10 SLC39A12 SLC20A1 SLC20A2 SLC2A13 SLC39A5	1.28e-04	150	103	6	GO:0015293
GeneOntologyMolecularFunction	zinc ion transmembrane transporter activity	SLC39A10 SLC39A12 SLC39A5	2.49e-04	24	103	3	GO:0005385
GeneOntologyMolecularFunction	dihydropyrimidinase activity	DPYSL2 CRMP1	3.90e-04	6	103	2	GO:0004157
GeneOntologyMolecularFunction	bicarbonate transmembrane transporter activity	SLC39A10 SLC39A12 SLC39A5	5.93e-04	32	103	3	GO:0015106
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC39A10 SLC39A12 CLCN6 SLC20A1 SLC20A2 SLC2A13 SLC39A5	8.63e-04	296	103	7	GO:0015291
GeneOntologyBiologicalProcess	zinc ion import across plasma membrane	SLC39A10 SLC39A12 SLC39A5	1.94e-05	11	103	3	GO:0071578
GeneOntologyCellularComponent	USH2 complex	PDZD7 USH2A	1.49e-04	4	105	2	GO:1990696
GeneOntologyCellularComponent	stereocilia ankle link	PDZD7 USH2A	3.70e-04	6	105	2	GO:0002141
GeneOntologyCellularComponent	stereocilia ankle link complex	PDZD7 USH2A	3.70e-04	6	105	2	GO:0002142
Domain	Amidohydro_1	DPYSL2 CAD CRMP1	1.90e-05	10	103	3	PF01979
Domain	Metal-dep_hydrolase_composite	DPYSL2 CAD CRMP1	1.90e-05	10	103	3	IPR011059
Domain	Amidohydro-rel	DPYSL2 CAD CRMP1	2.60e-05	11	103	3	IPR006680
Domain	Phos_transporter	SLC20A1 SLC20A2	3.01e-05	2	103	2	IPR001204
Domain	PHO4	SLC20A1 SLC20A2	3.01e-05	2	103	2	PF01384
Domain	ZIP	SLC39A10 SLC39A12 SLC39A5	5.67e-05	14	103	3	IPR003689
Domain	Zip	SLC39A10 SLC39A12 SLC39A5	5.67e-05	14	103	3	PF02535
Domain	Cdc42_effect	CDC42EP4 CDC42EP5	2.98e-04	5	103	2	IPR029273
Domain	BORG_CEP	CDC42EP4 CDC42EP5	2.98e-04	5	103	2	PF14957
Domain	Metal_Hydrolase	DPYSL2 CAD CRMP1	3.03e-04	24	103	3	IPR032466
Domain	Hydantoinase/dihydroPyrase	DPYSL2 CRMP1	4.45e-04	6	103	2	IPR011778
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	RAF1 ZSWIM8 TUT4 BICRA PATZ1 ZNF316 FBRS WRNIP1 BCKDHA LGALS3BP PJA2 ARID1B ZNF608 SH3TC1 NAT10 CLMP NOVA2	4.13e-08	1116	105	17	31753913
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CACNA1A RAF1 DPYSL2 VPS18 CAD RPS10 WRNIP1 CLASP2 CRMP1 CKB CLCN6 GUCY1A2 SNAP91 TLN1 SCN2A RPS10P5 SNTA1 SDHA	2.75e-07	1431	105	18	37142655
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	EPS15 CAD SMNDC1 RPS10 BCKDHA PSMD8 CLASP2 SLC39A10 IPO4 CEMIP2 LGALS3BP PJA2 ABCB10 SLC20A1 TLN1 NAT10 AKAP11 SDHA	4.81e-07	1487	105	18	33957083
Pubmed	The LZT proteins; the LIV-1 subfamily of zinc transporters.	SLC39A10 SLC39A12 SLC39A5	1.48e-06	8	105	3	12659941
Pubmed	EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking.	EPS15 SNAP91 CLINT1	2.22e-06	9	105	3	12538641
Pubmed	Human transcription factor protein interaction networks.	CAD BICRA TLX3 RPS10 FBRS PSMB7 PUM2 PSMD8 LGALS3BP CKB FHAD1 ARID1B ZNF608 NAT10 SP9 SIX5	6.04e-06	1429	105	16	35140242
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ARSJ BICRA ZNF316 FBRS CLASP2 COMTD1 EML3 ARHGEF10L HEYL MEGF8 SH3TC1 TLN1 ZNF324B SDHA	6.14e-06	1105	105	14	35748872
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	RAF1 RANBP2 DPYSL2 PSMB7 WRNIP1 PSMD8 IPO4 CKB PTPRO UFD1 RPS10P5 SNTA1 SDHA	7.80e-06	974	105	13	28675297
Pubmed	The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia.	NOVA1 NOVA2	9.03e-06	2	105	2	9789075
Pubmed	Phosphate-dependent FGF23 secretion is modulated by PiT2/Slc20a2.	SLC20A1 SLC20A2	9.03e-06	2	105	2	29551636
Pubmed	Phosphorylation of CRMP2 (collapsin response mediator protein 2) is involved in proper dendritic field organization.	DPYSL2 CRMP1	9.03e-06	2	105	2	22279220
Pubmed	Sodium-dependent phosphate cotransporters and phosphate-induced calcification of vascular smooth muscle cells: redundant roles for PiT-1 and PiT-2.	SLC20A1 SLC20A2	9.03e-06	2	105	2	23968976
Pubmed	Slc20a1 and Slc20a2 regulate neuronal plasticity and cognition independently of their phosphate transport ability.	SLC20A1 SLC20A2	9.03e-06	2	105	2	38195526
Pubmed	Mapping of the minimal inorganic phosphate transporting unit of human PiT2 suggests a structure universal to PiT-related proteins from all kingdoms of life.	SLC20A1 SLC20A2	9.03e-06	2	105	2	21586110
Pubmed	Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains.	NOVA1 NOVA2	9.03e-06	2	105	2	10368286
Pubmed	Loss of CRMP1 and CRMP2 results in migration defects of Purkinje cells in the X lobule of the mouse cerebellum.	DPYSL2 CRMP1	9.03e-06	2	105	2	35219721
Pubmed	Two highly conserved glutamate residues critical for type III sodium-dependent phosphate transport revealed by uncoupling transport function from retroviral receptor function.	SLC20A1 SLC20A2	9.03e-06	2	105	2	12205090
Pubmed	Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls.	NOVA1 NOVA2	9.03e-06	2	105	2	20558669
Pubmed	An RNA map predicting Nova-dependent splicing regulation.	NOVA1 NOVA2	9.03e-06	2	105	2	17065982
Pubmed	Functional characterization of SLC39 family members ZIP5 and ZIP10 in overexpressing HEK293 cells reveals selective copper transport activity.	SLC39A10 SLC39A5	9.03e-06	2	105	2	36454509
Pubmed	CLIP identifies Nova-regulated RNA networks in the brain.	NOVA1 NOVA2	9.03e-06	2	105	2	14615540
Pubmed	A family of retroviruses that utilize related phosphate transporters for cell entry.	SLC20A1 SLC20A2	9.03e-06	2	105	2	7966619
Pubmed	Eps15 homology domain-NPF motif interactions regulate clathrin coat assembly during synaptic vesicle recycling.	EPS15 SNAP91	9.03e-06	2	105	2	12807910
Pubmed	HITS-CLIP yields genome-wide insights into brain alternative RNA processing.	NOVA1 NOVA2	9.03e-06	2	105	2	18978773
Pubmed	Inorganic phosphate regulates Glvr-1 and -2 expression: role of calcium and ERK1/2.	SLC20A1 SLC20A2	9.03e-06	2	105	2	19232318
Pubmed	Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survival.	SLC20A1 SLC20A2	9.03e-06	2	105	2	32080237
Pubmed	Inhibition of ubiquitin-specific protease 13-mediated degradation of Raf1 kinase by Spautin-1 has opposing effects in naïve and primed pluripotent stem cells.	RAF1 USP13	9.03e-06	2	105	2	34688658
Pubmed	The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain.	NOVA1 NOVA2	9.03e-06	2	105	2	10811881
Pubmed	Deciphering PiT transport kinetics and substrate specificity using electrophysiology and flux measurements.	SLC20A1 SLC20A2	9.03e-06	2	105	2	17494632
Pubmed	Nova regulates brain-specific splicing to shape the synapse.	NOVA1 NOVA2	9.03e-06	2	105	2	16041372
Pubmed	Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters.	SLC20A1 SLC20A2	9.03e-06	2	105	2	8041748
Pubmed	Characterization of transport mechanisms and determinants critical for Na+-dependent Pi symport of the PiT family paralogs human PiT1 and PiT2.	SLC20A1 SLC20A2	9.03e-06	2	105	2	16790504
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	RANBP2 PATZ1 TRO WRNIP1 PSMD8 ALX4 LGALS3BP FOXD4L1 SH3TC1 SIX5 NOVA1 NOVA2	1.11e-05	857	105	12	25609649
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	ZSWIM8 RANBP2 GATD3 VPS18 CAD SMNDC1 RPS10 PSMB7 PSMD8 IPO4 CKB PJA2 UFD1 RPS10P5 SDHA	1.17e-05	1335	105	15	29229926
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	EPS15 DPYSL2 TUT4 WWOX SMNDC1 WRNIP1 PUM2 CLASP2 CEMIP2 ARID1B SLC20A1	1.40e-05	733	105	11	34672954
Pubmed	Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10-p63 axis in epithelial homeostasis.	SLC39A10 SLC39A12 SLC39A5	1.76e-05	17	105	3	29078349
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RANBP2 CAD RPS10 WRNIP1 PSMD8 CLASP2 IPO4 TLN1 NAT10 CLINT1	2.43e-05	638	105	10	33239621
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	RAF1 RANBP2 CAD RPS10 PSMB7 WRNIP1 BCKDHA PSMD8 IPO4 LGALS3BP ERGIC1 UFD1 RPS10P5 SDHA	2.58e-05	1257	105	14	37317656
Pubmed	Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4.	DPYSL2 CRMP1	2.70e-05	3	105	2	32156571
Pubmed	Expression of collapsin response mediator proteins 1, 2 and 5 is differentially regulated in newly generated and mature neurons of the adult olfactory system.	DPYSL2 CRMP1	2.70e-05	3	105	2	15926912
Pubmed	PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome.	PDZD7 USH2A	2.70e-05	3	105	2	20440071
Pubmed	Biallelic variants in genes previously associated with dominant inheritance: CACNA1A, RET and SLC20A2.	CACNA1A SLC20A2	2.70e-05	3	105	2	34267336
Pubmed	CRMP1 and CRMP2 have synergistic but distinct roles in dendritic development.	DPYSL2 CRMP1	2.70e-05	3	105	2	27480924
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ZSWIM8 RANBP2 DPYSL2 CAD RPS10 IPO4 CKB TLN1 NAT10 SDHA	2.96e-05	653	105	10	22586326
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	RAF1 MYH4 RANBP2 VPS18 SMNDC1 RPS10 BCKDHA PSMD8 CLASP2 IPO4 EML3 LGALS3BP NAT10 AKAP11	3.26e-05	1284	105	14	17353931
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TOB2 TRO PUM2 SLC39A10 PJA2 MEGF8 TBC1D1 TLN1	3.41e-05	407	105	8	12693553
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	RANBP2 DPYSL2 CAD RPS10 PSMB7 BCKDHA CKB UFD1 CLINT1	3.61e-05	534	105	9	35032548
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	RAF1 GATD3 TUT4 CAD WWOX NADK2 PSMB7 PUM2 BCKDHA LGALS3BP CKB ABCB10 NAT10 AKAP11 SDHA	4.36e-05	1496	105	15	32877691
Pubmed	Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways.	MYH4 DPYSL2 CUBN CKB SDHA	5.20e-05	132	105	5	22496890
Pubmed	The alternative splicing factor Nova2 regulates vascular development and lumen formation.	NOVA1 NOVA2	5.40e-05	4	105	2	26446569
Pubmed	Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.	ARID1B SCN2A	5.40e-05	4	105	2	26637798
Pubmed	The Ulip family phosphoproteins--common and specific properties.	DPYSL2 CRMP1	5.40e-05	4	105	2	9652388
Pubmed	Individual USH2 proteins make distinct contributions to the ankle link complex during development of the mouse cochlear stereociliary bundle.	PDZD7 USH2A	5.40e-05	4	105	2	26401052
Pubmed	Usher Syndrome Type II	PDZD7 USH2A	5.40e-05	4	105	2	20301515
Pubmed	Characterization of a gamma-adaptin ear-binding motif in enthoprotin.	EPS15 CLINT1	5.40e-05	4	105	2	14675752
Pubmed	Localization of PDZD7 to the stereocilia ankle-link associates this scaffolding protein with the Usher syndrome protein network.	PDZD7 USH2A	5.40e-05	4	105	2	23055499
Pubmed	Ubiquitin-recognition protein Ufd1 couples the endoplasmic reticulum (ER) stress response to cell cycle control.	USP13 UFD1	5.40e-05	4	105	2	21571647
Pubmed	Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous system.	DPYSL2 CRMP1	5.40e-05	4	105	2	10664068
Pubmed	Whirlin and PDZ domain-containing 7 (PDZD7) proteins are both required to form the quaternary protein complex associated with Usher syndrome type 2.	PDZD7 USH2A	5.40e-05	4	105	2	25406310
Pubmed	A functional coupling between CRMP1 and Nav1.7 for retrograde propagation of Semaphorin3A signaling.	DPYSL2 CRMP1	5.40e-05	4	105	2	28254884
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	RANBP2 CAD RPS10 WRNIP1 PSMD8 IPO4 CKB PJA2 SDHA	6.05e-05	571	105	9	37167062
Pubmed	Proteomic analysis of the NOS2 interactome in human airway epithelial cells.	ZSWIM8 CAD PSMB7 PSMD8 LGALS3BP	6.42e-05	138	105	5	23438482
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	PUM2 CLCN6 ZNF608 TBC1D1 TLN1 AKAP11	6.47e-05	225	105	6	12168954
Pubmed	Global landscape of HIV-human protein complexes.	RANBP2 PUM2 IPO4 EML3 LGALS3BP ERGIC1 ABCB10 SDHA	7.66e-05	457	105	8	22190034
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	CACNA1A MBOAT1 PATZ1 PDZD7 GUCY1A2 SIX5	7.85e-05	233	105	6	37704626
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	FBRS WRNIP1 MUC19 CKB ARID1B UFD1 NAT10	7.90e-05	339	105	7	30415952
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	RANBP2 CAD RPS10 IPO4 ABCB10 RPS10P5 SDHA	8.65e-05	344	105	7	36282215
Pubmed	Rescuing Z+ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing.	NOVA1 NOVA2	8.97e-05	5	105	2	19221030
Pubmed	Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly.	EPS15 SNAP91	8.97e-05	5	105	2	10430869
Pubmed	Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo.	DPYSL2 CRMP1	8.97e-05	5	105	2	16611631
Pubmed	Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice.	PDZD7 USH2A	8.97e-05	5	105	2	24334608
Pubmed	The Borg family of Cdc42 effector proteins Cdc42EP1-5.	CDC42EP4 CDC42EP5	8.97e-05	5	105	2	27913681
Pubmed	Spinal Muscular Atrophy	SMNDC1 ERGIC1	8.97e-05	5	105	2	20301526
Pubmed	p80 ROKalpha binding protein is a novel splice variant of CRMP-1 which associates with CRMP-2 and modulates RhoA-induced neuronal morphology.	DPYSL2 CRMP1	8.97e-05	5	105	2	12482610
Pubmed	A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.	DPYSL2 CRMP1	8.97e-05	5	105	2	8973361
Pubmed	Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain.	DPYSL2 CRMP1	8.97e-05	5	105	2	15834957
Pubmed	Identification of novel transcription-regulating genes expressed during murine molar development.	RPS10 RPS10P5 EMX2	9.23e-05	29	105	3	22639370
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	WWOX RPS10 CLASP2 CRMP1 SNAP91 RPS10P5	1.06e-04	246	105	6	15345747
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	RAF1 RANBP2 GATD3 CAD PSMB7 BCKDHA IPO4 LGALS3BP CKB TLN1 UFD1 NAT10 CLINT1 SDHA	1.11e-04	1440	105	14	30833792
Pubmed	Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones.	LRAT SRD5A3 CUBN	1.13e-04	31	105	3	15583024
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	RANBP2 PSMB7 WRNIP1 LMBR1 PSMD8 IPO4 PJA2 ABCB10 TLN1 CLINT1 SDHA	1.33e-04	942	105	11	31073040
Pubmed	Metallothionein-3 is a component of a multiprotein complex in the mouse brain.	DPYSL2 CKB	1.34e-04	6	105	2	17018872
Pubmed	Phylogenetic conservation of a limb-specific, cis-acting regulator of Sonic hedgehog ( Shh).	LMBR1 ALX4	1.34e-04	6	105	2	14727139
Pubmed	A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing.	NOVA1 NOVA2	1.34e-04	6	105	2	10829067
Pubmed	Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.	CACNA1A NRXN3	1.34e-04	6	105	2	12827191
Pubmed	Identification of mouse brain proteins associated with isoform 3 of metallothionein.	DPYSL2 CKB	1.34e-04	6	105	2	15802640
Pubmed	Numb promotes an increase in skeletal muscle progenitor cells in the embryonic somite.	ALX4 HEYL	1.34e-04	6	105	2	19785007
Pubmed	An alternative splicing program promotes adipose tissue thermogenesis.	NOVA1 NOVA2	1.34e-04	6	105	2	27635635
Pubmed	Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.	DPYSL2 CRMP1	1.34e-04	6	105	2	10956643
Pubmed	Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1.	SLC20A1 SLC20A2	1.34e-04	6	105	2	19882669
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	ZSWIM8 CAD RPS10 PSMB7 LGALS3BP PJA2 CLCN6 UFD1 CLINT1	1.42e-04	639	105	9	23443559
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZSWIM8 CLASP2 SNAP91 CLINT1	1.44e-04	87	105	4	12465718
Pubmed	Global proteomics of Ubqln2-based murine models of ALS.	EPS15 USP13 RPS10 PJA2 UFD1 CLINT1	1.46e-04	261	105	6	33277362
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	CDC42EP4 WWOX BCKDHA SLC39A10 CEMIP2 ERGIC1 ABCB10 SLC20A1 SLC20A2 AKAP11 CLINT1	1.46e-04	952	105	11	38569033
Pubmed	ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.	RAF1 DPYSL2 CAD LGALS3BP SDHA	1.53e-04	166	105	5	35687106
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	MYH4 RANBP2 CAD PSMD8 IPO4 LGALS3BP PJA2 ABCB10 SDHA	1.55e-04	647	105	9	26618866
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	EPS15 DPYSL2 TUT4 SRD5A3 WWOX BICRA LMBR1 CLASP2 ALX4 ERGIC1 ZNF608 SH3TC1 TBC1D1 NAT10	1.57e-04	1489	105	14	28611215
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1A EPS15 RANBP2 DPYSL2 CAD PATZ1 CLASP2 IPO4 CRMP1 SNAP91 NAT10	1.62e-04	963	105	11	28671696
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	USP13 RANBP2 CAD BICRA ZNF608 NAT10	1.82e-04	272	105	6	31010829
Pubmed	Gene-environment interaction in the etiology of mathematical ability using SNP sets.	ARID1B GUCY1A2	1.88e-04	7	105	2	20978832
Cytoband	2p22-p21	CAD PUM2	1.44e-04	8	105	2	2p22-p21
GeneFamily	Fibronectin type III domain containing\|USH2 complex	PDZD7 USH2A	8.08e-05	4	67	2	1244
GeneFamily	CDC42 effector proteins	CDC42EP4 CDC42EP5	1.34e-04	5	67	2	1164
GeneFamily	Solute carriers	SLC39A10 SLC22A12 SLC39A12 SLC20A1 SLC20A2 SLC2A13 SLC39A5	6.34e-04	395	67	7	752
GeneFamily	NKL subclass homeoboxes and pseudogenes	HMX3 TLX3 EMX2	1.97e-03	67	67	3	519
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBML5	MUC19 PDZD7 COMTD1 CRMP1 NRXN3 PTPRO SPOCK3 SCN2A EMX2 USH2A NOVA1 NOVA2	3.71e-07	465	105	12	M39066
Coexpression	KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP	EPS15 DPYSL2 RPS10 PUM2 PSMD8 CLASP2 CRMP1 CKB CLCN6 SNAP91 SLC20A1 CLINT1 SNTA1 SDHA	1.96e-06	755	105	14	M2105
Coexpression	KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP	CACNA1A EPS15 DPYSL2 RPS10 PUM2 PSMD8 CRMP1 PJA2 CLCN6 AKAP11 SNTA1 SDHA	1.82e-05	680	105	12	M2107
Coexpression	LEE_AGING_CEREBELLUM_UP	EPS15 LGALS3BP PTPRO TBC1D1 SNTA1	2.25e-05	84	105	5	M1599
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	POMT2 SRD5A3 RPS10 SLC39A10 IPO4 ERGIC1 ABCB10 CLCN6 SLC20A1 SLC20A2 TLN1 RPS10P5	2.53e-05	703	105	12	MM1055
Coexpression	LEE_AGING_CEREBELLUM_UP	EPS15 LGALS3BP PTPRO TBC1D1 SNTA1	2.67e-05	87	105	5	MM1023
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRN	GPR155 DPYSL2 COMTD1 CRMP1 SNAP91 PTPRO EMX2 NOVA1	6.23e-05	335	105	8	M39065
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VPS18 ARSJ TRO SLC20A1 SCN2A SLC2A13	5.12e-06	185	105	6	87151ab95530e70d61328b336518df58db584acb
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARSJ MBOAT1 KCNK13 NRXN3 TBC1D1 SCN2A	5.12e-06	185	105	6	3d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCell	Frontal_cortex-Neuronal\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CRMP1 PJA2 NRXN3 SNAP91 SCN2A AKAP11	7.77e-06	199	105	6	f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Interneuron\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	ARSJ CEMIP2 NRXN3 SP9	3.50e-05	78	105	4	8ad496ccbffb62a50f195c3789a95d8c80e2272d
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FREM3 NRXN3 SPOCK3 SP9 SLC2A13	3.99e-05	161	105	5	b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KCNK13 LMAN1L PTPRO SPOCK3 SP9	4.36e-05	164	105	5	08819970174a3eb4eee8e1e675075828665b845e
ToppCell	facs-Lung-Endomucin-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHAD1 CLCN6 PTPRO SLC20A2 SLC39A5	4.61e-05	166	105	5	a2ce44702a0cd5fa5872cac3302d3c451205feef
ToppCell	facs-Lung-Endomucin-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHAD1 CLCN6 PTPRO SLC20A2 SLC39A5	4.61e-05	166	105	5	0f641302a6b71c4badaaf20f51162bfc2386b167
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR155 RPS10 CUBN HEYL USH2A	5.77e-05	174	105	5	f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC39A10 LGALS3BP ARHGEF10L CKB SNTA1	6.26e-05	177	105	5	26bad614560609d318bfc9c235a698bca4e1c22c
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDC42EP4 EML3 SLC39A12 SIX5 EMX2	6.43e-05	178	105	5	4813d6509738f088c12ebf395b70d496af04649a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARSJ MBOAT1 KCNK13 CEMIP2 SCN2A	7.14e-05	182	105	5	f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1A CRMP1 SPOCK3 SLC20A1 SCN2A	7.14e-05	182	105	5	1923932a9c60e9ec33db69ded441210d1fb07bec
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1A CRMP1 SPOCK3 SLC20A1 SCN2A	7.14e-05	182	105	5	69ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NLRP11 MUC19 CUBN SLC22A12 USH2A	7.32e-05	183	105	5	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TOB2 TUT4 ZNF608 TLN1 CLINT1	7.51e-05	184	105	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DPYSL2 CRMP1 HEYL NRXN3 GUCY1A2	7.71e-05	185	105	5	a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARSJ MBOAT1 KCNK13 ZNF608 SCN2A	7.71e-05	185	105	5	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMX3 CLASP2 CRMP1 SNAP91 SCN2A	7.91e-05	186	105	5	15f2e5905486e33f6f7b3b3e9758a0559e8c61ee
ToppCell	Cerebellum-Neuronal\|Cerebellum / BrainAtlas - Mouse McCarroll V32	USP13 TRO CRMP1 PJA2 SLC2A13	8.11e-05	187	105	5	61b9d6eb131a674598aa8409d7fa909c8765442d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A TRO NRXN3 SNAP91 SCN2A	8.11e-05	187	105	5	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARSJ MBOAT1 KCNK13 TBC1D1 SCN2A	8.11e-05	187	105	5	2d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCell	21-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	CACNA1A CRMP1 SPOCK3 SCN2A NOVA1	8.32e-05	188	105	5	e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A TOB2 HEYL TBC1D1 TLN1	8.53e-05	189	105	5	d69b7a01dd4d6ad043bb6210e9ab34b49578389c
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A TOB2 HEYL TBC1D1 TLN1	8.53e-05	189	105	5	2b5f1b4f173a224342ea4f10b193ee33b7662699
ToppCell	3'-Adult-Distal_Rectal-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A TOB2 HEYL TBC1D1 TLN1	8.53e-05	189	105	5	43e131458d8a4b120f7a5fb3d0c5650abded15f6
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron\|World / Primary Cells by Cluster	CEMIP2 NRXN3 ZNF608 SPOCK3 SP9	8.96e-05	191	105	5	4dd9c8117c4499ed9bde127baf2598603a82080d
ToppCell	15-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	CACNA1A KCNK13 CRMP1 SPOCK3 SCN2A	8.96e-05	191	105	5	76311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TLX3 CLASP2 CRMP1 SPOCK3 SCN2A	8.96e-05	191	105	5	73b15ffa60d592c43aaa575f1b1479d49a66dfe8
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CRMP1 PJA2 NRXN3 SCN2A SLC2A13	9.18e-05	192	105	5	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ARSJ HEYL SLC20A1 CLMP NOVA1	9.18e-05	192	105	5	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	21-Trachea-Epithelial-Epithelial\|Trachea / Age, Tissue, Lineage and Cell class	CRMP1 SNAP91 SP9 EMX2 NOVA1	9.41e-05	193	105	5	9a8bb44a37f3202e3123a6680bd5545dc91a6d40
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRMP1 GUCY1A2 SNAP91 SCN2A SLC2A13	9.41e-05	193	105	5	461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRMP1 GUCY1A2 SNAP91 SCN2A SLC2A13	9.41e-05	193	105	5	0dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDC42EP4 COL27A1 SNAP91 CLMP NOVA1	9.64e-05	194	105	5	f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRAT HEYL NRXN3 CLCA1 GUCY1A2	9.64e-05	194	105	5	415801a3dfacf05f2b603fb424df3d045190a812
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRAT HEYL NRXN3 CLCA1 GUCY1A2	9.64e-05	194	105	5	256cb33ec90328f2704921fb0fe0fd9812e138b0
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDC42EP4 NADK2 CKB PJA2 NOVA1	9.64e-05	194	105	5	8b81f039f5b25d35a4d5a41b27d4d9360ba22f15
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRAT HEYL NRXN3 CLCA1 GUCY1A2	9.64e-05	194	105	5	7942bc83c1bdca687795b91aa232824d603f9b09
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDC42EP4 COL27A1 SNAP91 CLMP NOVA1	9.87e-05	195	105	5	1be9502577267ca2a04656a99d57e3e2f124d92e
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRO CRMP1 SNAP91 SCN2A SLC2A13	9.87e-05	195	105	5	ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF10L ADK SCN2A CLINT1 EMX2	1.01e-04	196	105	5	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	frontal_cortex-Neuronal\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TRO PJA2 NRXN3 SNAP91 SCN2A	1.01e-04	196	105	5	de7d10da862f98894ce47244fbc992f4a12d63bb
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMX3 CRMP1 SNAP91 SPOCK3 SCN2A	1.04e-04	197	105	5	a1ae1aa797762a3768e14434c7e5cd19c595ecb3
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1A NRXN3 SNAP91 SCN2A SLC2A13	1.06e-04	198	105	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1A NRXN3 SNAP91 SCN2A SLC2A13	1.06e-04	198	105	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMX3 TLX3 CLASP2 CRMP1 SPOCK3	1.06e-04	198	105	5	6483d412b6c0aab58b3348f99231caa5daf65025
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1A NRXN3 SNAP91 SCN2A SLC2A13	1.06e-04	198	105	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A PTPRO SCN2A SLC2A13 NOVA1	1.11e-04	200	105	5	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A PTPRO SCN2A SLC2A13 NOVA1	1.11e-04	200	105	5	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Interneuron\|3m / Sample Type, Dataset, Time_group, and Cell type.	CRMP1 NRXN3 ZNF608 SPOCK3 SP9	1.11e-04	200	105	5	a313b9a8bde1ea80a6eae183b76fba46b86558b4
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1A NRXN3 SNAP91 SCN2A SLC2A13	1.11e-04	200	105	5	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A PTPRO SCN2A SLC2A13 NOVA1	1.11e-04	200	105	5	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Interneuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	CRMP1 NRXN3 ZNF608 SPOCK3 SCN2A	1.11e-04	200	105	5	f5c63ef52bd7a898cf009b8bf9b2f7f4890d1c9b
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A PTPRO SCN2A SLC2A13 NOVA1	1.11e-04	200	105	5	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A PTPRO SCN2A SLC2A13 NOVA1	1.11e-04	200	105	5	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal\|6m / Sample Type, Dataset, Time_group, and Cell type.	CLASP2 CRMP1 SNAP91 PTPRO SCN2A	1.11e-04	200	105	5	cedbc47b1defb5973cf7ab6baaa2d6f2fd481f88
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Cortical_neuron\|6m / Sample Type, Dataset, Time_group, and Cell type.	CLASP2 CRMP1 SNAP91 PTPRO SCN2A	1.11e-04	200	105	5	6f7ff0533339fcc9d316f2c77334a79c1409ec4f
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A PTPRO SCN2A SLC2A13 NOVA1	1.11e-04	200	105	5	961858738ce35db8760c8c2e136f8369bc444ccf
Drug	Tranexamic acid [1197-18-8]; Up 200; 25.4uM; PC3; HT_HG-U133A	POMT2 TUT4 TRO CRMP1 NRXN3 CLCA1 MEGF8 SPOCK3	3.59e-06	200	103	8	5762_UP
Disease	Usher syndrome type 2A (is_implicated_in)	PDZD7 USH2A	1.16e-05	2	101	2	DOID:0110838 (is_implicated_in)
Disease	USHER SYNDROME, TYPE IIA	PDZD7 USH2A	1.16e-05	2	101	2	276901
Disease	USHER SYNDROME, TYPE IIA	PDZD7 USH2A	1.16e-05	2	101	2	C1848634
Disease	Usher syndrome type 2A	PDZD7 USH2A	1.16e-05	2	101	2	cv:C1848634
Disease	Usher syndrome type 2	PDZD7 USH2A	3.47e-05	3	101	2	C0339534
Disease	Usher Syndrome, Type II	PDZD7 USH2A	1.15e-04	5	101	2	C1568249
Disease	response to antidepressant	HMX3 MUC19 ALX4 NRXN3 TBC1D1	3.56e-04	176	101	5	GO_0036276
Disease	major depressive episode	FREM3 CEMIP2 SLC39A12	5.66e-04	47	101	3	EFO_0007634
Disease	triacylglycerol 58:12 measurement	MBOAT1 NRXN3	7.49e-04	12	101	2	EFO_0010439
Disease	Crohn's disease	GATD3 SMNDC1 MUC19 NRXN3 TBC1D1 AKAP11 SLC2A13	8.17e-04	441	101	7	EFO_0000384
Disease	lysophosphatidylcholine 14:0 measurement	CAD GUCY1A2	1.18e-03	15	101	2	EFO_0010356
Disease	synophrys measurement	ALX4 SLC39A12 ZNF608	1.66e-03	68	101	3	EFO_0007906
Disease	cardiomyopathy (implicated_via_orthology)	RAF1 MYH4 SDHA	1.88e-03	71	101	3	DOID:0050700 (implicated_via_orthology)
Disease	reaction time measurement	GPR155 DPYSL2 WWOX MUC19 PJA2 SNAP91 PTPRO TBC1D1	1.92e-03	658	101	8	EFO_0008393
Disease	glucose measurement	LMAN1L ABCB10 MEGF8 SNAP91 SPOCK3 SP9	1.99e-03	380	101	6	EFO_0004468
Disease	C-reactive protein measurement	ZSWIM8 TOB2 CAD WWOX ZNF316 AGBL5 EML3 HEYL ZNF608 TBC1D1 SP9	2.80e-03	1206	101	11	EFO_0004458
Disease	Colorectal Carcinoma	DPYSL2 VPS18 CAD CUBN ARHGEF10L ABCB10 GUCY1A2 SH3TC1	2.86e-03	702	101	8	C0009402
Disease	medial orbital frontal cortex volume measurement	NRXN3 SPOCK3	3.31e-03	25	101	2	EFO_0010315

Protein segments in the cluster

Peptide	Gene	Start	Entry
TFLSAAAKAQGFGDA	ALX4	46	Q9H161
GGLLFSSRFDSGNLA	AGBL5	6	Q8NDL9
SGALVAFAFTGNSKG	CACNA1A	1321	O00555
VSNGDAADAAFSGAR	ARHGEF10L	91	Q9HCE6
DTNGAGDAFVGGFLS	ADK	311	P55263
GDAFVGGFLSQLVSD	ADK	316	P55263
EAFARAGFFGATGLS	ABCB10	391	Q9NRK6
LAADSGIGQEGASFA	AKAP11	1671	Q9UKA4
AAAGSAAGGFQRFAG	ARID1B	476	Q8NFD5
SGVIDLFGDAFGSSA	SNAP91	636	O60641
ISNGFGFKDAVFDGS	RAF1	11	P04049
ADLASSNSGDFAFGS	RANBP2	2851	P49792
GNSLGAAIGSALSGF	PUM2	556	Q8TB72
AIAAGIFNDLGSGSN	PSMB7	201	Q99436
STGGSADLFGGFADF	CLINT1	336	Q14677
ADLFGGFADFGSAAA	CLINT1	341	Q14677
GFENATQALGRAAFG	LGALS3BP	66	Q08380
GGVFDVSNADRLGFS	CKB	331	P12277
VDGGTSFEFNDGAIA	NADK2	411	Q4G0N4
AAGGLFLSTLNFSGE	NLRP11	401	P59045
ADDFFQGTKAALAGG	DPYSL2	86	Q16555
VENFLDGLGNSFSGS	GPR155	241	Q7Z3F1
AAAKGALEGAAGFAL	HMX3	71	A6NHT5
GNASLSTFGFVGAAL	LMBR1	336	Q8WVP7
GGFFGVSAATGTLAD	LMAN1L	226	Q9HAT1
RGFDTFFGSLLGSGD	ARSJ	191	Q5FYB0
GFGAAKNLSTFAVDG	GATD3B	136	A0A0B4J2D5
AGKGDAAFGFEVSDS	MUC19	261	Q7Z5P9
GGAAFLSGALQAGFE	PDZD7	896	Q9H5P4
GAFNALGGADRLTSN	ERGIC1	166	Q969X5
GFILFNSGDGNDFIA	NRXN3	906	Q9Y4C0
GANGSADSQGLLFFR	MEGF8	2626	Q7Z7M0
TGGTGFFDARALAVD	HEYL	101	Q9NQ87
NFTLFSSGAAGEDKG	LRAT	21	O95237
LARDNEFSGGVGAFA	KCNK13	381	Q9HB14
GALGSFALAAAANGY	NOVA2	351	Q9UNW9
FALAAAANGYLGAGA	NOVA2	356	Q9UNW9
LVAAAAAAGAAGGFL	NOVA2	381	Q9UNW9
AAAGAAGGFLTAEKL	NOVA2	386	Q9UNW9
SAALGLAIAGAVAFG	NAT10	291	Q9H0A0
GAGTFVNFASLERDG	PTPRO	856	Q16827
FESVFSAQLGDGGAA	PATZ1	66	Q9HBE1
GAAQFQGGELALSAF	SRD5A3	116	Q9H8P0
RFISDGSGSGTGFQA	CUBN	1831	O60494
AAGLLGANSASFSQA	DERPC	281	P0CG12
FVSAGAAAGVAAAFG	CLCN6	241	P51797
ASLAALSNGAFGGLG	FBRS	181	Q9HAH7
FSGNSAVFTAGKAAG	FHAD1	641	B1AJZ9
LGSAALGAAFATGLF	COMTD1	16	Q86VU5
GRAGDAFGDTSFLNS	CDC42EP4	41	Q9H3Q1
FADNGIGLTFASDGS	CEMIP2	801	Q9UHN6
GTAAAAAARGGGFLF	COL27A1	11	Q8IZC6
VGRGGDAFGDTSFLS	CDC42EP5	36	Q6NZY7
TLADAVNNAAGFGFS	MBOAT1	301	Q6ZNC8
GFGAAKNLSTFAVDG	GATD3	136	P0DPI2
LSDNFAATAAASGGG	FOXD4L1	361	Q9NU39
PFLNGFHSAAAAAAG	EMX2	46	Q04743
GAFERGVGALAFSAA	EML3	356	Q32P44
GVGALAFSAADQGAF	EML3	361	Q32P44
GNESFGGGFADFSTL	EPS15	716	P42566
GGGFADFSTLSKVNN	EPS15	721	P42566
GFADLNLAEFAGSGS	FAM102A	101	Q5T9C2
ANSAFIAARGSFDGS	GRK1	11	Q15835
LNGNSVFGGAGAASA	BICRA	301	Q9NZM4
LNSLGFSFGHGLTAA	SLC22A12	236	Q96S37
AFSVGANDVANSFGT	SLC20A1	36	Q8WUM9
AFSVGANDVANSFGT	SLC20A2	21	Q08357
NFSDGLAIGAAFSAG	SLC39A10	681	Q9ULF5
HNFADGLAIGAAFSS	SLC39A12	551	Q504Y0
ALAAAAGGDSFAPFF	IPO4	841	Q8TEX9
ADDFFQGTRAALVGG	CRMP1	86	Q14194
ASEGDAHAGFNFAAT	BCKDHA	241	P12694
GSLAAATAATNGYFG	NOVA1	386	P51513
AVGGTLQDFFNGFDA	GUCY1A2	191	P33402
AAVSALAGGALNGVF	SLC2A13	131	Q96QE2
GFAILEGGSFNLSSN	FREM3	836	P0C091
ASLNEGAQFLGAGFL	USH2A	1711	O75445
SSDDGASLLFLDFGG	SNTA1	456	Q13424
GDGFFSSAFQARLSG	POMT2	311	Q9UKY4
GAGLRAAFGLSEAGF	SDHA	71	P31040
AEAAAQGSIFLAGTG	SIX5	296	Q8N196
AVGLASALADFQGSG	SH3TC1	306	Q8TE82
AFLFSGAQTAEAEGG	MYH4	621	Q9Y623
GGLFSNSAAAAAAAA	SP9	106	P0CG40
LTDGLAIGAAFSDGF	SLC39A5	396	Q6ZMH5
AIGAAFSDGFSSGLS	SLC39A5	401	Q6ZMH5
GRVAFASNFLAGDAS	CLMP	81	Q9H6B4
NGLIDAFGALSSGNG	CLCA1	466	A8K7I4
GAGALNAGSYASLED	CLASP2	396	O75122
EAGAGSATEFQFRGG	RPS10	141	P46783
RFFEAAAGSGSSAGA	MISP3	101	Q96FF7
AEAGAGSATEFQFRG	RPS10P5	151	Q9NQ39
AGFSDGASISFNGAP	TRO	731	Q12816
SAGFGGALSTAADFG	TRO	1106	Q12816
SGRFGQDFSTFLEAG	TLN1	1271	Q9Y490
FIGRAAEGAEAQGFS	VPS18	231	Q9P253
AEGAEAQGFSGLFAA	VPS18	236	Q9P253
QDGGLRSSGFFSSFE	TBC1D1	251	Q86TI0
AASAESRDFSGAGGI	SCN2A	466	Q99250
SRDFSGAGGIGVFSE	SCN2A	471	Q99250
GANSGIGFETAKSFA	WWOX	131	Q9NZC7
AAFALGGLGSGFASN	CAD	556	P27708
ASFAGLGAPFEDAGS	TLX3	61	O43711
VAAAGGRSDGGNFLD	SPOCK3	26	Q9BQ16
ADAAEAATAFGASGG	WRNIP1	191	Q96S55
SSLALGAEASTFGGF	ZSWIM8	626	A7E2V4
AGGRFVAFSGEGQSL	UFD1	286	Q92890
RGSALLEFAGGTSFG	ZNF316	971	A6NFI3
ISQGGDFAAFLLQGA	WDR93	201	Q6P2C0
SGAGATAALADGLKF	ZNF608	71	Q9ULD9
NGTAAITFAGYGNAE	SMNDC1	101	O75940
AAAVNGAAGFSSSGP	PSMD8	66	P48556
FGSSKNGFGFRDSDL	TUT4	996	Q5TAX3
SLGDEAAAAGAFAQA	TTC34	476	A8MYJ7
SLFDGFADGLGVAEA	PJA2	551	O43164
GSPSLFFDAADGQGS	TOB2	266	Q14106
AASAGASVFGASGLD	USP13	711	Q92995
AFGNASDLKAASGGR	ZNF324B	206	Q6AW86