Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent protein folding chaperone	HYOU1 CCT8L2 CCT8L1P HSPA8 HSPA9	1.73e-05	40	162	5	GO:0140662
MousePheno	abnormal chorioallantoic fusion	SUPT20HL1 SUPT20HL2 PTK2 PIGQ IPO9 UBR5 TMED2 CRB2	2.19e-06	90	133	8	MP:0002824
MousePheno	abnormal allantois morphology	SUPT20HL1 SUPT20HL2 PTK2 PIGQ IPO9 UBR5 TMED2 CRB2	1.13e-05	112	133	8	MP:0001726
MousePheno	abnormal placenta development	SUPT20HL1 ASH1L SUPT20HL2 PTK2 PIGQ IPO9 UBR5 TMED2 CRB2	2.18e-05	160	133	9	MP:0001712
MousePheno	abnormal placenta physiology	SUPT20HL1 ASH1L SUPT20HL2 PTK2 PIGQ IPO9 UBR5 TMED2 NIPBL CRB2	2.50e-05	204	133	10	MP:0010038
MousePheno	abnormal extraembryonic tissue physiology	SUPT20HL1 UBR4 ASH1L SUPT20HL2 TEK BIRC6 PTK2 PIGQ IPO9 UBR5 TMED2 NIPBL CRB2	2.50e-05	345	133	13	MP:0004264
Domain	-	STK36 RIPOR2 CIP2A SCYL3 TOGARAM1 TMCO6 HEATR5A AP3B1 IPO9 TELO2 UTP20 PRKDC NIPBL	4.64e-08	222	156	13	1.25.10.10
Domain	ARM-type_fold	STK36 RIPOR2 CIP2A UBR4 SCYL3 TOGARAM1 TMCO6 HEATR5A AP3B1 URB1 IPO9 TELO2 UTP20 PRKDC NIPBL	1.68e-07	339	156	15	IPR016024
Domain	ARM-like	STK36 RIPOR2 CIP2A SCYL3 TOGARAM1 TMCO6 HEATR5A AP3B1 IPO9 TELO2 UTP20 PRKDC NIPBL	4.47e-07	270	156	13	IPR011989
Domain	LMBR1	LMBR1 LMBR1L LMBRD1	2.27e-06	4	156	3	PF04791
Domain	LMBR1-like_membr_prot	LMBR1 LMBR1L LMBRD1	2.27e-06	4	156	3	IPR006876
Domain	HEAT	STK36 SCYL3 TOGARAM1 UTP20 PRKDC NIPBL	8.72e-06	58	156	6	IPR000357
Domain	HEAT_REPEAT	SCYL3 TOGARAM1 HEATR5A UTP20 PRKDC NIPBL	2.60e-05	70	156	6	PS50077
Domain	ACTININ_2	FLNA SYNE1 LCP1 PLS1	3.66e-05	23	156	4	PS00020
Domain	ACTININ_1	FLNA SYNE1 LCP1 PLS1	3.66e-05	23	156	4	PS00019
Domain	Actinin_actin-bd_CS	FLNA SYNE1 LCP1 PLS1	3.66e-05	23	156	4	IPR001589
Domain	LIMR	LMBR1 LMBR1L	6.93e-05	2	156	2	IPR008075
Domain	-	HYOU1 HSPA8 HSPA9	1.19e-04	12	156	3	2.60.34.10
Domain	HSP70_peptide-bd	HYOU1 HSPA8 HSPA9	1.19e-04	12	156	3	IPR029047
Domain	-	HYOU1 HSPA8 HSPA9	1.54e-04	13	156	3	1.20.1270.10
Domain	Heat_shock_70_CS	HYOU1 HSPA8 HSPA9	1.54e-04	13	156	3	IPR018181
Domain	HSP70_C	HYOU1 HSPA8 HSPA9	1.54e-04	13	156	3	IPR029048
Domain	Cadherin_2	PCDHB6 PCDHB2 PCDHA13 PCDH20 PCDH10	2.10e-04	65	156	5	PF08266
Domain	Cadherin_N	PCDHB6 PCDHB2 PCDHA13 PCDH20 PCDH10	2.10e-04	65	156	5	IPR013164
Domain	HSP70	HYOU1 HSPA8 HSPA9	2.96e-04	16	156	3	PF00012
Domain	Cadherin_CS	PCDHB6 PCDHB2 PCDHA13 PCDH20 DCHS1 PCDH10	3.08e-04	109	156	6	IPR020894
Domain	HSP70_2	HYOU1 HSPA8 HSPA9	3.57e-04	17	156	3	PS00329
Domain	HSP70_1	HYOU1 HSPA8 HSPA9	3.57e-04	17	156	3	PS00297
Domain	HSP70_3	HYOU1 HSPA8 HSPA9	3.57e-04	17	156	3	PS01036
Domain	CADHERIN_1	PCDHB6 PCDHB2 PCDHA13 PCDH20 DCHS1 PCDH10	3.73e-04	113	156	6	PS00232
Domain	Cadherin	PCDHB6 PCDHB2 PCDHA13 PCDH20 DCHS1 PCDH10	3.73e-04	113	156	6	PF00028
Domain	CADHERIN_2	PCDHB6 PCDHB2 PCDHA13 PCDH20 DCHS1 PCDH10	3.92e-04	114	156	6	PS50268
Domain	-	PCDHB6 PCDHB2 PCDHA13 PCDH20 DCHS1 PCDH10	3.92e-04	114	156	6	2.60.40.60
Domain	CA	PCDHB6 PCDHB2 PCDHA13 PCDH20 DCHS1 PCDH10	4.10e-04	115	156	6	SM00112
Domain	Hsp_70_fam	HYOU1 HSPA8 HSPA9	4.25e-04	18	156	3	IPR013126
Domain	Cadherin-like	PCDHB6 PCDHB2 PCDHA13 PCDH20 DCHS1 PCDH10	4.30e-04	116	156	6	IPR015919
Domain	MFS_1	SLC17A2 SLC22A17 SLC18A3 SLC22A10 SLC16A11	4.64e-04	77	156	5	PF07690
Domain	MFS	SLC17A2 SLC22A17 SLC18A3 SLC22A10 SLC16A11	4.64e-04	77	156	5	IPR011701
Domain	Cadherin	PCDHB6 PCDHB2 PCDHA13 PCDH20 DCHS1 PCDH10	4.71e-04	118	156	6	IPR002126
Domain	HEAT	STK36 SCYL3 UTP20 PRKDC	6.85e-04	48	156	4	PF02985
Domain	MFS_dom	SLC17A2 SLC22A17 SLC18A3 CLN3 SLC22A10 SLC16A11	9.19e-04	134	156	6	IPR020846
Domain	ZnF_UBR1	UBR4 UBR5	1.42e-03	7	156	2	SM00396
Domain	ZF_UBR	UBR4 UBR5	1.42e-03	7	156	2	PS51157
Domain	zf-UBR	UBR4 UBR5	1.42e-03	7	156	2	PF02207
Domain	Znf_UBR	UBR4 UBR5	1.42e-03	7	156	2	IPR003126
Domain	BIR	NAIP BIRC6	1.88e-03	8	156	2	PF00653
Domain	BIR_REPEAT_2	NAIP BIRC6	1.88e-03	8	156	2	PS50143
Domain	BIR	NAIP BIRC6	1.88e-03	8	156	2	SM00238
Domain	Calx_beta	ADGRV1 SLC8A3	1.88e-03	8	156	2	SM00237
Domain	-	NAIP BIRC6	1.88e-03	8	156	2	1.10.1170.10
Domain	BIR_rpt	NAIP BIRC6	1.88e-03	8	156	2	IPR001370
Domain	BIR_REPEAT_1	NAIP BIRC6	1.88e-03	8	156	2	PS01282
Domain	MFS	SLC17A2 SLC22A17 SLC18A3 SLC22A10 SLC16A11	2.13e-03	108	156	5	PS50850
Domain	CH	FLNA SYNE1 LCP1 PLS1	2.13e-03	65	156	4	SM00033
Domain	Calx_beta	ADGRV1 SLC8A3	2.40e-03	9	156	2	IPR003644
Domain	rSAM	ELP3 TYW1B	2.40e-03	9	156	2	IPR007197
Domain	Radical_SAM	ELP3 TYW1B	2.40e-03	9	156	2	PF04055
Domain	Calx-beta	ADGRV1 SLC8A3	2.40e-03	9	156	2	PF03160
Domain	CH	FLNA SYNE1 LCP1 PLS1	2.80e-03	70	156	4	PF00307
Domain	-	FLNA SYNE1 LCP1 PLS1	2.95e-03	71	156	4	1.10.418.10
Domain	VIT	VWA5B2 ITIH6	2.99e-03	10	156	2	PS51468
Domain	VIT	VWA5B2 ITIH6	2.99e-03	10	156	2	IPR013694
Domain	CH	FLNA SYNE1 LCP1 PLS1	3.26e-03	73	156	4	PS50021
Domain	CH-domain	FLNA SYNE1 LCP1 PLS1	3.59e-03	75	156	4	IPR001715
Domain	LAM_G_DOMAIN	HSPG2 LAMA4 CRB2	3.89e-03	38	156	3	PS50025
Domain	UBX	UBXN4 UBXN2A	4.33e-03	12	156	2	SM00166
Domain	Laminin_G_2	HSPG2 LAMA4 CRB2	4.50e-03	40	156	3	PF02210
Domain	UBX_dom	UBXN4 UBXN2A	5.09e-03	13	156	2	IPR001012
Domain	UBX	UBXN4 UBXN2A	5.09e-03	13	156	2	PF00789
Domain	UBX	UBXN4 UBXN2A	5.09e-03	13	156	2	PS50033
Domain	Cadherin_C	PCDHB6 PCDHB2 PCDH10	5.17e-03	42	156	3	IPR032455
Domain	Cadherin_C_2	PCDHB6 PCDHB2 PCDH10	5.17e-03	42	156	3	PF16492
Domain	LamG	HSPG2 LAMA4 CRB2	5.89e-03	44	156	3	SM00282
Domain	Dynein_HC_stalk	DNHD1 DNAH3	5.91e-03	14	156	2	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH3	5.91e-03	14	156	2	IPR013602
Domain	DHC_N2	DNHD1 DNAH3	5.91e-03	14	156	2	PF08393
Domain	MT	DNHD1 DNAH3	5.91e-03	14	156	2	PF12777
Domain	Tyr_kinase_cat_dom	TEK PTK2 TYRO3 MUSK	6.34e-03	88	156	4	IPR020635
Domain	TyrKc	TEK PTK2 TYRO3 MUSK	6.34e-03	88	156	4	SM00219
Domain	DHC_fam	DNHD1 DNAH3	6.78e-03	15	156	2	IPR026983
Domain	Dynein_heavy	DNHD1 DNAH3	6.78e-03	15	156	2	PF03028
Domain	Dynein_heavy_dom	DNHD1 DNAH3	6.78e-03	15	156	2	IPR004273
Domain	AAA	DNAH3 ABCA2 FIGNL2 NAIP PEX1	7.24e-03	144	156	5	SM00382
Domain	AAA+_ATPase	DNAH3 ABCA2 FIGNL2 NAIP PEX1	7.24e-03	144	156	5	IPR003593
Domain	-	HSPG2 LAMA4 ADGRV1 CRB2	8.28e-03	95	156	4	2.60.120.200
Pubmed	Identification of a putative lysosomal cobalamin exporter altered in the cblF defect of vitamin B12 metabolism.	LMBR1 LMBR1L LMBRD1	1.01e-07	3	163	3	19136951
Pubmed	LMBRD1: the gene for the cblF defect of vitamin B₁₂ metabolism.	LMBR1 LMBR1L LMBRD1	1.01e-07	3	163	3	20446115
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	FLNA HYOU1 CIP2A UBR4 PEX1 LMBR1 LRRC40 AP3B1 FANCD2 URB1 IPO9 LMBR1L UBR5 TELO2 NUP210 UTP20 PRKDC VARS1 CAPN15	1.06e-07	942	163	19	31073040
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	FLNA UBR4 LCP1 CREG1 BIRC6 ARPC1B IPO9 PRKDC VARS1 HSPA9 SEC23B	7.60e-07	344	163	11	30333137
Pubmed	Functional proteomics mapping of a human signaling pathway.	A2M HSPG2 FLNA EVC2 PSAP CPXM2 HLA-B UBR4 ASH1L LAMA4 HIPK3 PIGQ SUSD1 UBR5	8.55e-07	591	163	14	15231748
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	FLNA HYOU1 CIP2A UBR4 LRRC40 AP3B1 IPO9 TELO2 NUP210 PKN2 PRKDC VARS1 HSPA8 HSPA9	2.09e-06	638	163	14	33239621
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNA HYOU1 UBR4 LCP1 LARP4 BIRC6 URB1 UBR5 NUP210 UTP20 PRKDC NIPBL HSPA9 SEC23B	2.73e-06	653	163	14	22586326
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	HLA-B CIP2A BIRC6 ARPC1B FANCD2 URB1 UBR5 TELO2 PRKDC VARS1 HSPA8 HSPA9 SEC23B	3.29e-06	571	163	13	37167062
Pubmed	Protein profile of exosomes from trabecular meshwork cells.	A2M HSPG2 FLNA LAMA4 HSPA8	3.43e-06	49	163	5	21362503
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	A2M FLNA HYOU1 CIP2A UBR4 LCP1 AP3B1 ELP3 FANCD2 SEPSECS UBR5 TELO2 NUP210 PRKDC PLS1 VARS1 SNTA1	3.65e-06	974	163	17	28675297
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 HSPG2 FLNA STK36 ABCA2 SZT2 CTC1 UBR4 AKNA TMCO6 PANX1 BIRC6 MXRA7 ARHGEF10L TLNRD1 URB1 CLN3 PRKDC	4.83e-06	1105	163	18	35748872
Pubmed	Evidence that the transcriptional repressor ICER is regulated via the N-end rule for ubiquitination.	UBR4 PRKDC VARS1 HSPA9	8.72e-06	28	163	4	35227662
Pubmed	Defining the membrane proteome of NK cells.	FLNA ABCA2 HYOU1 HLA-B UBR4 AKNA LRRC40 PANX1 MSH3 AP3B1 LARP4 BIRC6 IPO9 UBR5 NUP210 PRKDC LMBRD1 HSPA8	1.03e-05	1168	163	18	19946888
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	VWA5B2 DNAH3 SYNE1 UBR4 AKNA SLC18A3 MAST1 HSF1	1.53e-05	233	163	8	37704626
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	FLNA PSAP HYOU1 UBR4 AP3B1 ELP3 BIRC6 ARPC1B FANCD2 IPO9 TELO2 NFRKB PRKDC HSF1 PLS1 VARS1 HSPA8 HSPA9 SEC23B RABGGTA	1.70e-05	1455	163	20	22863883
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FLNA EXO5 STRIP1 FANCD2 ZBTB7A SLC41A3 CLN3 NFRKB UTP20 PKN2 PRKDC HSF1 NIPBL HSPA8	1.85e-05	774	163	14	15302935
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNA UBR4 LRRC40 MSH3 LARP4 ELP3 BIRC6 ARPC1B PTK2 URB1 IPO9 UBR5 UTP20 PKN2 PRKDC NIPBL VARS1 HSPA8 HSPA9	2.09e-05	1353	163	19	29467282
Pubmed	Targeting an Achilles' heel of cancer with a WRN helicase inhibitor.	FANCD2 PRKDC	2.18e-05	2	163	2	24036544
Pubmed	Characterization of interleukin 2 stimulated 65-kilodalton phosphoprotein in human T cells.	LCP1 PLS1	2.18e-05	2	163	2	2111166
Pubmed	The transcriptional coactivator PGC1α protects against hyperthermic stress via cooperation with the heat shock factor HSF1.	PPARGC1A HSF1	2.18e-05	2	163	2	26890141
Pubmed	Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish.	HSPA8 IQCG	2.18e-05	2	163	2	24787902
Pubmed	Feedback regulation of heat shock factor 1 (Hsf1) activity by Hsp70-mediated trimer unzipping and dissociation from DNA.	HSF1 HSPA8	2.18e-05	2	163	2	32490574
Pubmed	Identification of I-plastin, a human fimbrin isoform expressed in intestine and kidney.	LCP1 PLS1	2.18e-05	2	163	2	8139549
Pubmed	Antibody-mediated protection against Cryptococcus neoformans pulmonary infection is dependent on B cells.	FCGR2A PRKDC	2.18e-05	2	163	2	15664957
Pubmed	METTL3-mediated HSPA9 m6A modification promotes malignant transformation and inhibits cellular senescence by regulating exosomal mortalin protein in cervical cancer.	METTL3 HSPA9	2.18e-05	2	163	2	38253218
Pubmed	Heat shock factor-1 and the heat shock cognate 70 protein associate in high molecular weight complexes in the cytoplasm of NIH-3T3 cells.	HSF1 HSPA8	2.18e-05	2	163	2	7639722
Pubmed	Fancd2 functions in a double strand break repair pathway that is distinct from non-homologous end joining.	FANCD2 PRKDC	2.18e-05	2	163	2	16135554
Pubmed	Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1α Transcriptional Axis.	PPARGC1A HSF1	2.18e-05	2	163	2	26344102
Pubmed	Analysis of HSPA8 and HSPA9 mRNA expression and promoter methylation in the brain and blood of Alzheimer's disease patients.	HSPA8 HSPA9	2.18e-05	2	163	2	23948933
Pubmed	The m6A methyltransferase METTL3 modifies PGC-1α mRNA promoting mitochondrial dysfunction and oxLDL-induced inflammation in monocytes.	METTL3 PPARGC1A	2.18e-05	2	163	2	34375639
Pubmed	A plant alkaloid, veratridine, potentiates cancer chemosensitivity by UBXN2A-dependent inhibition of an oncoprotein, mortalin-2.	UBXN2A HSPA9	2.18e-05	2	163	2	26188124
Pubmed	L-plastin is essential for alveolar macrophage production and control of pulmonary pneumococcal infection.	LCP1 PLS1	2.18e-05	2	163	2	24595139
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CASP8AP2 HYOU1 MRPL12 SYNE1 CIP2A UBR4 GATB LRRC40 AP3B1 LCMT2 MXRA7 URB1 UBXN4 UBR5 TELO2 NUP210 TMED2 PKN2 HSPA8 HSPA9	2.32e-05	1487	163	20	33957083
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHB6 PCDHB2 PCDHA13 PCDH20 PCDH10	2.64e-05	74	163	5	10817752
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHB6 PCDHB2 PCDHA13 PCDH20 PCDH10	3.20e-05	77	163	5	10835267
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHB6 PCDHB2 PCDHA13 PCDH20 PCDH10	3.85e-05	80	163	5	10716726
Pubmed	Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes.	UBR4 BIRC6 UBR5 HSPA8	4.11e-05	41	163	4	32723828
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DNHD1 FLNA HYOU1 SYNE1 UBR4 LRRC40 MSH3 AP3B1 FANCD2 JARID2 URB1 IPO9 NUP210 UTP20 PRKDC NIPBL VARS1 HSPA8 HSPA9	4.23e-05	1425	163	19	30948266
Pubmed	IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.	FLNA ELP3 PRKDC	4.41e-05	15	163	3	18303054
Pubmed	Identification of potential protein interactors of Lrrk2.	PRKDC HSPA8 HSPA9	4.41e-05	15	163	3	17400507
Pubmed	TRIM6 promotes colorectal cancer cells proliferation and response to thiostrepton by TIS21/FoxM1.	A2M FLNA HSPA8 HSPA9	4.98e-05	43	163	4	31992359
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	FLNA RIPOR2 PSAP HYOU1 CTC1 ASH1L PEX1 AP3B1 LCMT2 PPARGC1A URB1 SEPSECS TYW1B NFRKB LMBRD1 TRIM37	5.45e-05	1084	163	16	11544199
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	A2M HYOU1 CIP2A UBR4 ARPC1B IPO9 UBR5 NUP210 PRKDC HSPA8 HSPA9 SEC23B	5.88e-05	647	163	12	26618866
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	FLNA UBR5 NUP210 NFRKB UTP20 PRKDC NIPBL	6.36e-05	210	163	7	16565220
Pubmed	Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.	SUPT20HL1 PCDHB6 GATB PEX1 SUPT20HL2 LARP4 ZBTB7A PKN2 PRKDC LCOR	6.41e-05	457	163	10	32968282
Pubmed	Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis.	PIGQ KCNT1	6.53e-05	3	163	2	24463883
Pubmed	Assessment of Three New Loci from Genome-wide Association Study in Essential Tremor in Chinese population.	PPARGC1A CTNNA3	6.53e-05	3	163	2	28801652
Pubmed	Sequential expression and differential localization of I-, L-, and T-fimbrin during differentiation of the mouse intestine and yolk sac.	LCP1 PLS1	6.53e-05	3	163	2	7655078
Pubmed	The Roles of Actin-Binding Domains 1 and 2 in the Calcium-Dependent Regulation of Actin Filament Bundling by Human Plastins.	LCP1 PLS1	6.53e-05	3	163	2	28694070
Pubmed	METTL3-Mediated RNA m6A Modification Regulates the Angiogenic Behaviors of Retinal Endothelial Cells by Methylating MMP2 and TIE2.	METTL3 TEK	6.53e-05	3	163	2	37819742
Pubmed	Human plastin genes. Comparative gene structure, chromosome location, and differential expression in normal and neoplastic cells.	LCP1 PLS1	6.53e-05	3	163	2	8428952
Pubmed	Interactions of a PPARGC1A Variant and a PNPLA3 Variant Affect Nonalcoholic Steatohepatitis in Severely Obese Taiwanese Patients.	PPARGC1A PNPLA3	6.53e-05	3	163	2	27015186
Pubmed	Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.	FANCD2 POLQ	6.53e-05	3	163	2	25642963
Pubmed	HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability.	ATRIP TELO2	6.53e-05	3	163	2	17384638
Pubmed	Genome-wide association study in essential tremor identifies three new loci.	PPARGC1A CTNNA3	6.53e-05	3	163	2	27797806
Pubmed	UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD.	UBR4 UBR5	6.53e-05	3	163	2	32558906
Pubmed	Heat shock transcription factor 1 binds selectively in vitro to Ku protein and the catalytic subunit of the DNA-dependent protein kinase.	PRKDC HSF1	6.53e-05	3	163	2	9325337
Pubmed	Ubiquitin-like (UBX)-domain-containing protein, UBXN2A, promotes cell death by interfering with the p53-Mortalin interactions in colon cancer cells.	UBXN2A HSPA9	6.53e-05	3	163	2	24625977
Pubmed	Heat shock transcription factor 1 is SUMOylated in the activated trimeric state.	HSF1 HSPA8	6.53e-05	3	163	2	33493517
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 MUSK	6.53e-05	3	163	2	10878022
Pubmed	UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK.	PRKDC POLQ	6.53e-05	3	163	2	16520097
Pubmed	Modification of two distinct COOH-terminal domains is required for murine p53 activation by bacterial Hsp70.	PRKDC HSPA8	6.53e-05	3	163	2	8940078
Pubmed	Molecular cloning and characterization of plastin, a human leukocyte protein expressed in transformed human fibroblasts.	LCP1 PLS1	6.53e-05	3	163	2	3211125
Pubmed	Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2.	JARID2 PRKDC	6.53e-05	3	163	2	25645357
Pubmed	The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.	SUPT20HL1 SUPT20HL2	6.53e-05	3	163	2	24220028
Pubmed	Tyro3-mediated phosphorylation of ACTN4 at tyrosines is FAK-dependent and decreases susceptibility to cleavage by m-Calpain.	PTK2 TYRO3	6.53e-05	3	163	2	29274473
Pubmed	Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.	FLNA PSAP ARPC1B IPO9 HSPA8 HSPA9	7.63e-05	149	163	6	26370502
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	HYOU1 SCYL3 PEX1 PANX1 MXRA7 UBXN4 SLC41A3 NUP210 TMED2 SEC23B	7.80e-05	468	163	10	31056421
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	FLNA LCP1 PLS1	7.83e-05	18	163	3	12119179
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	SYNE1 ADGRV1 CTNNA3 PLS1 HSPA8 HSPA9	8.52e-05	152	163	6	34299191
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	CASP8AP2 UBR4 ASH1L HEATR5A PCDH10 KCNT1	8.84e-05	153	163	6	10718198
Pubmed	Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.	ATRIP TELO2 PRKDC	9.27e-05	19	163	3	20801936
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CASP8AP2 SYNE1 TOGARAM1 ADGRV1 BIRC6 URB1 UBR5	9.79e-05	225	163	7	12168954
Pubmed	Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data.	FLNA SYNE1 LCP1 HSPA8	1.06e-04	52	163	4	26499835
Pubmed	Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins.	PKN2 PRKDC HSPA8	1.09e-04	20	163	3	22504172
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	UBR4 ELP3 PPOX FANCD2 JARID2 UBR5 PRKDC HSPA8 HSPA9	1.13e-04	396	163	9	26687479
Pubmed	Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.	FLNA HLA-B MRPL12 NUP210 PRKDC HSPA9	1.13e-04	160	163	6	23798571
Pubmed	The Effect of the NFκB-USP9X-Cx43 Axis on the Dynamic Balance of Bone Formation/Degradation during Ossification of the Posterior Longitudinal Ligament of the Cervical Spine.	A2M FLNA HSPA8 HSPA9	1.23e-04	54	163	4	35391932
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	FLNA HYOU1 MRPL12 UBR4 LRRC40 AP3B1 LARP4 ELP3 BIRC6 UBR5 PKN2 PRKDC HSF1 NIPBL VARS1 HSPA8 HSPA9 SEC23B	1.23e-04	1415	163	18	28515276
Pubmed	IAPs: more than just inhibitors of apoptosis proteins.	NAIP BIRC6	1.30e-04	4	163	2	18414036
Pubmed	A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.	UBR4 UBR5	1.30e-04	4	163	2	16055722
Pubmed	Molecular chaperones as HSF1-specific transcriptional repressors.	HSF1 HSPA8	1.30e-04	4	163	2	9499401
Pubmed	Common and distinct roles for the binding partners Rabenosyn-5 and Vps45 in the regulation of endocytic trafficking in mammalian cells.	PTK2 HSPA8	1.30e-04	4	163	2	19931244
Pubmed	FGL2-targeting T cells exhibit antitumor effects on glioblastoma and recruit tumor-specific brain-resident memory T cells.	FCGR2A PRKDC	1.30e-04	4	163	2	36759517
Pubmed	Androgen-induced cell migration: role of androgen receptor/filamin A association.	FLNA PTK2	1.30e-04	4	163	2	21359179
Pubmed	Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival.	HSPA8 HSPA9	1.30e-04	4	163	2	14993262
Pubmed	LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance.	EPOR ZBTB7A	1.30e-04	4	163	2	23134786
Pubmed	αvβ5 Integrin/FAK/PGC-1α Pathway Confers Protective Effects on Retinal Pigment Epithelium.	PTK2 PPARGC1A	1.30e-04	4	163	2	26244551
Pubmed	HCLK2 is required for activity of the DNA damage response kinase ATR.	ATRIP TELO2	1.30e-04	4	163	2	19097996
Pubmed	Alpha-2-macroglobulin gene, oxidized low-density lipoprotein receptor-1 locus, and sporadic Alzheimer's disease.	A2M OPRL1	1.30e-04	4	163	2	18191876
Pubmed	Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity.	LCP1 PLS1	1.30e-04	4	163	2	14756805
Pubmed	FcγRIIb and BAFF differentially regulate peritoneal B1 cell survival.	FCGR2A PRKDC	1.30e-04	4	163	2	22516957
Pubmed	Differential localization of villin and fimbrin during development of the mouse visceral endoderm and intestinal epithelium.	LCP1 PLS1	1.30e-04	4	163	2	2686960
Pubmed	The substrate recognition domains of the N-end rule pathway.	UBR4 UBR5	1.30e-04	4	163	2	19008229
Pubmed	Fidgetin-like 2 depletion enhances cell migration by regulating GEF-H1, RhoA, and FAK.	FIGNL2 PTK2	1.30e-04	4	163	2	36523161
Pubmed	Identification of Filamin A as a BRCA1-interacting protein required for efficient DNA repair.	FLNA PRKDC	1.30e-04	4	163	2	20305393
Pubmed	Structural studies of UBXN2A and mortalin interaction and the putative role of silenced UBXN2A in preventing response to chemotherapy.	UBXN2A HSPA9	1.30e-04	4	163	2	26634371
Pubmed	Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases.	MAST1 SNTA1	1.30e-04	4	163	2	10404183
Pubmed	White Adipose Tissue Depots Respond to Chronic Beta-3 Adrenergic Receptor Activation in a Sexually Dimorphic and Depot Divergent Manner.	PPARGC1A HSPA9	1.30e-04	4	163	2	34943961
Pubmed	Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells.	PTK2 HSPA8 HSPA9	1.46e-04	22	163	3	15657067
Interaction	PDGFRB interactions	A2M HYOU1 UBR4 SCYL3 TEK PTK2 FANCD2 NUP210 PRKDC HSF1 LCOR	1.69e-06	228	156	11	int:PDGFRB
Interaction	HLA-B interactions	ABCA2 HLA-B PCDH20 FANCD2 TELO2 CLN3 PRKDC LCOR VARS1 HSPA8 MUSK	2.66e-06	239	156	11	int:HLA-B
GeneFamily	Solute carriers	SLC17A2 SLC34A3 SLC22A17 SLC9C1 SLC8A3 SLC25A43 SLC41A3 SLC18A3 SLC22A10 SLC36A3 SLC16A11 SLC51A	3.47e-06	395	106	12	752
GeneFamily	Heat shock 70kDa proteins	HYOU1 HSPA8 HSPA9	1.25e-04	17	106	3	583
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR4 UBR5	7.01e-04	7	106	2	785
GeneFamily	Ring finger proteins\|Baculoviral IAP repeat containing\|Caspase recruitment domain containing	NAIP BIRC6	9.32e-04	8	106	2	419
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	TEK TYRO3 MUSK	1.65e-03	40	106	3	321
GeneFamily	Non-clustered protocadherins	PCDH20 PCDH10	2.16e-03	12	106	2	21
GeneFamily	UBX domain containing	UBXN4 UBXN2A	2.55e-03	13	106	2	364
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	UBR4 HEATR5A ARHGEF10L STRIP1 JARID2 CCT8L2 UBR5 NFRKB	3.74e-08	135	163	8	3351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	SZT2 UBR4 HEATR5A ARHGEF10L STRIP1 JARID2 CCT8L2 NFRKB	8.06e-08	149	163	8	768877bade04ca0321593b8470b5011ad8270431
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PADI4 RIPOR2 HLA-B LCP1 SLC8A3 FCGR2A GPSM3	3.03e-06	169	163	7	2e15a9317da4017757d184f7cc91bd66b072ac51
ToppCell	droplet-Marrow-nan-21m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA PADI4 PSAP LCP1 ARPC1B PIGQ GPSM3	5.31e-06	184	163	7	d071f53ad9e957dc0f8ae9c53aaa31cfebcf815e
ToppCell	COVID-19_Severe-gd_T\|COVID-19_Severe / Disease condition and Cell class	A2M FLNA RIPOR2 HLA-B SYNE1 AKNA LCP1	5.31e-06	184	163	7	791f1bcb954aadc63d4117c400537d036f68734d
ToppCell	droplet-Marrow-nan-21m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA PADI4 PSAP LCP1 ARPC1B PIGQ GPSM3	5.90e-06	187	163	7	20b25b0d08550a1e8e997c5ce67d8e34bf7fc398
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	LMBR1 HEATR5A MSH3 ADGRV1 LRRC58 BIRC6 PRKDC	7.26e-06	193	163	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA PSAP LCP1 ARPC1B ARHGEF10L SUSD1 PNPLA3	7.26e-06	193	163	7	222829c30ebe47f0ed1e035897e3cd4be10b2a11
ToppCell	Monocytes\|World / lung cells shred on cell class, cell subclass, sample id	PADI4 RIPOR2 PSAP HLA-B NAIP LCP1 GPSM3	7.26e-06	193	163	7	d66d3927f8fbe1544b5cfa5ee91a7f4a0ef1e810
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-Activated_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPOR2 HLA-B AKNA LCP1 ARPC1B GPSM3 HSPA8	7.51e-06	194	163	7	e3705346755cbf65fc276d4d4fbee936ed6bb7bf
ToppCell	Control-CD8+_Tem\|Control / Disease condition and Cell class	A2M FLNA HLA-B SYNE1 AKNA LCP1 MXRA7	7.76e-06	195	163	7	7503b3e032f95b350a2782d28e4d412a8dc9ebcc
ToppCell	COVID-19_Severe-CD8+_Tem\|COVID-19_Severe / Disease condition and Cell class	A2M FLNA HLA-B SYNE1 AKNA LCP1 MXRA7	7.76e-06	195	163	7	ff7ae62393e1c858a10592db8e6d9f36b8bae396
ToppCell	T_cells-GZMK+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	A2M FLNA HLA-B SYNE1 AKNA LCP1 ZBTB7A	7.76e-06	195	163	7	003ea7ddec6c1c98d2f6470bb51ebd97450eb936
ToppCell	COVID-19_Severe-Lymphoid_T/NK-gd_T\|COVID-19_Severe / Disease group, lineage and cell class	A2M FLNA RIPOR2 HLA-B SYNE1 AKNA LCP1	7.76e-06	195	163	7	9990440bda7fac5d00ef80444fab07459be625e1
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLNA RIPOR2 HLA-B LCP1 FCGR2A GPSM3 PRKDC	8.03e-06	196	163	7	fe8d3f45a64323947c36b127355d5940eb56c0ca
ToppCell	Transplant_Alveoli_and_parenchyma-Immune-Neutrophils\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	PSAP HLA-B NAIP LCP1 JARID2 FCGR2A GPSM3	8.03e-06	196	163	7	376c5a459a484205fbb0db34936e4a6146d1f622
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	A2M FLNA RIPOR2 HLA-B SYNE1 AKNA LCP1	8.03e-06	196	163	7	418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	A2M FLNA RIPOR2 HLA-B SYNE1 AKNA LCP1	8.03e-06	196	163	7	581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	A2M FLNA RIPOR2 HLA-B SYNE1 AKNA LCP1	8.03e-06	196	163	7	6beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	A2M FLNA RIPOR2 HLA-B SYNE1 AKNA LCP1	8.03e-06	196	163	7	c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLNA RIPOR2 HLA-B LCP1 FCGR2A GPSM3 PRKDC	8.03e-06	196	163	7	526d037bb12d81f1c235c60ddc787fbad0bbad77
ToppCell	10x3'2.3-week_14-16-Myeloid_monocytic-monocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FLNA PADI4 PSAP NAIP LCP1 ARPC1B HIPK3	8.57e-06	198	163	7	eae8c29d68cc94bfbd15e487ad855639c2a4fcc9
ToppCell	10x3'2.3-week_14-16-Myeloid_monocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FLNA PADI4 PSAP NAIP LCP1 ARPC1B HIPK3	8.57e-06	198	163	7	2f94fb4a1719d5adddb4fd3dfaf099ee2b642011
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FLNA PSAP HLA-B LCP1 CREG1 ARPC1B FCGR2A	8.57e-06	198	163	7	2e470249edc7cf85bed550795ff84cbef22895c0
ToppCell	10x3'2.3-week_14-16-Myeloid_monocytic-monocyte-promonocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FLNA PADI4 PSAP NAIP LCP1 ARPC1B HIPK3	8.57e-06	198	163	7	ff634a17195d06a8614ed1c6564937d10ca5c00d
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PADI4 RIPOR2 PSAP NAIP LCP1 ARPC1B GPSM3	8.57e-06	198	163	7	6d547122b8c4ddbdd0d3dae3bce4a125740d5457
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPOR2 HLA-B LCP1 ARPC1B NUP210 GPSM3 HSPA8	8.86e-06	199	163	7	b01328a80db5bb088c44564cea0f6729b1a9805b
ToppCell	10x5'v1-week_12-13-Myeloid_monocytic\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FLNA PADI4 PSAP HLA-B NAIP LCP1 ARPC1B	8.86e-06	199	163	7	3d6fa56da7b6bc1e045f80ddfe460d2d5715567e
ToppCell	5'-GW_trimst-2-LymphNode\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPOR2 HLA-B LCP1 ARPC1B NUP210 GPSM3 HSPA8	8.86e-06	199	163	7	4a9ca133125dc25a06e7b1cfea15ecffa449c20e
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPOR2 HLA-B LCP1 ARPC1B NUP210 GPSM3 HSPA8	8.86e-06	199	163	7	45d0d275ffb4183e3e71f4701e121ef9853ebd10
ToppCell	10x5'v1-week_12-13-Myeloid_monocytic-monocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FLNA PADI4 PSAP HLA-B NAIP LCP1 ARPC1B	8.86e-06	199	163	7	3a50ca40f6147fac7ce0d201717781d3939bbebe
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPOR2 HLA-B LCP1 ARPC1B NUP210 GPSM3 HSPA8	8.86e-06	199	163	7	da20998253ad08a4a127a98b991b26237edb61a2
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PSAP NAIP LCP1 CREG1 ARPC1B FCGR2A GPSM3	9.15e-06	200	163	7	62868b0ba312e8b5ff3b2477a04d31aeac497b2b
ToppCell	Control-PLT_3\|Control / Disease Group and Platelet Clusters	FLNA PSAP HLA-B ARPC1B FCGR2A GPSM3	1.30e-05	140	163	6	82ea671f61d55f6896d903c5876b042e2f3385d6
ToppCell	PND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PADI4 RIPOR2 SYNE1 AKNA LCP1 PIGQ	1.85e-05	149	163	6	4de52569611e63a780cde9bd111d6d9c11a05a11
ToppCell	PND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PADI4 RIPOR2 SYNE1 AKNA LCP1 PIGQ	1.85e-05	149	163	6	c957ac23ad6343eacce7e6be4a6d3ac043af4f86
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 ABCA2 LMBR1 ADGRV1 GFRA1 DCHS1	2.66e-05	159	163	6	7ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	DNAH3 HEATR5A ARHGEF10L PNPLA3 POLQ KLB	2.96e-05	162	163	6	7d43d59531cbefe3ac94953b7faf7156b2a31441
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	A2M PCDHB6 PCDHB2 GFRA1 SLITRK6 PCDH10	3.17e-05	164	163	6	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M ABCA2 EVC2 SYNE1 LCP1 SLC16A11	3.17e-05	164	163	6	a5227971a71345854e0538e42da684de87febda0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 HLA-B LCP1 SLC8A3 FCGR2A GPSM3	3.17e-05	164	163	6	2c929996a19bbe29949010928001c277b5494a42
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PADI4 RIPOR2 HLA-B LCP1 FCGR2A GPSM3	3.39e-05	166	163	6	6a65dff1333f39ec8c584e6df04b8c1e7f1c8946
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Hematologic-proerythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 SYNE1 LCP1 ARPC1B PIGQ GPSM3	3.39e-05	166	163	6	a1211afc1197d078eb3db0d0f788ecaf4419aa5b
ToppCell	COVID-19_Mild-PLT_3\|COVID-19_Mild / Disease Group and Platelet Clusters	FLNA PSAP HLA-B ARPC1B FCGR2A GPSM3	3.87e-05	170	163	6	5ac1252ae3c026a506cfe26e3d119276fe364661
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 PADI4 LAMA4 TEK CTNNA3 TRIM37	4.13e-05	172	163	6	a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	EXO5 NAIP ADGRV1 CREG1 SCNN1D SLC16A11	4.27e-05	173	163	6	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M FLNA ABCA2 SYNE1 AKNA TXNDC2	4.70e-05	176	163	6	5914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCell	droplet-Marrow-nan-21m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA PADI4 SYNE1 LCP1 PIGQ GPSM3	4.70e-05	176	163	6	f7d8eb90489a6d22240179abeb0aa16ac24615d3
ToppCell	ILEUM-inflamed-(9)_Enteric_neurons\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PCDHB2 SLC22A17 GFRA1 DCHS1 SLITRK6 PCDH10	5.00e-05	178	163	6	d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 SYNE1 ASH1L UBXN2A PKN2 HSPA8	5.00e-05	178	163	6	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	LA-17._Lymphocyte\|World / Chamber and Cluster_Paper	RIPOR2 HLA-B AKNA LCP1 SLC8A3 NUP210	5.00e-05	178	163	6	34ec499d03cc198cfefa19a724d4c81974052f65
ToppCell	ILEUM-inflamed-(9)_Neuro_cell\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PCDHB2 SLC22A17 GFRA1 DCHS1 SLITRK6 PCDH10	5.00e-05	178	163	6	611504b0a9e6318b18fba83787b03f9245c82252
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CASP8AP2 EVC2 TEK ATRIP DCHS1 FRMD5	5.33e-05	180	163	6	baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CASP8AP2 EVC2 TEK ATRIP DCHS1 FRMD5	5.33e-05	180	163	6	2d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CASP8AP2 EVC2 TEK ATRIP DCHS1 FRMD5	5.33e-05	180	163	6	0f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 HSPG2 MXRA7 MAST1 SLC36A3 MUSK	5.49e-05	181	163	6	35eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 HSPG2 MXRA7 MAST1 SLC36A3 MUSK	5.49e-05	181	163	6	e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCell	LA-17._Lymphocyte\|LA / Chamber and Cluster_Paper	RIPOR2 HLA-B AKNA LCP1 SLC8A3 NUP210	5.49e-05	181	163	6	3fd9f805fa46141b0fa7023ee5d8688d338635d5
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Neutrophils\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PADI4 RIPOR2 NAIP LCP1 FCGR2A GPSM3	5.66e-05	182	163	6	243c783675df495ea4112dbf710712c44ea6b4f1
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	A2M HSPG2 CPXM2 LAMA4 TEK DCHS1	5.66e-05	182	163	6	d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Neutrophils-Neutrophils\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PADI4 RIPOR2 NAIP LCP1 FCGR2A GPSM3	5.66e-05	182	163	6	18790a394dc32b3cef99cdbf826392c520e38b4a
ToppCell	droplet-Marrow-nan-21m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 PSAP LCP1 ARPC1B PIGQ GPSM3	5.84e-05	183	163	6	71ea92cd20683230af314ff883b2624bd68382e1
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A17 PCDH20 GFRA1 SLITRK6 SNTA1 CHST3	5.84e-05	183	163	6	8330c39184ce076e1f95fd3725b68af551d89db0
ToppCell	Monocytes-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	PADI4 RIPOR2 PSAP HLA-B NAIP GPSM3	6.02e-05	184	163	6	d15405bf2a121570f6044546e98927b10ecc4354
ToppCell	wk_20-22-Epithelial-PNS-intermediate_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HSPG2 ABCA2 FIGNL2 CTNNA3 PCDH10 CHST3	6.02e-05	184	163	6	4e3ba64692868563a579902aa9c6f88cab5bce26
ToppCell	facs-Bladder-nan-18m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 RIPOR2 PSAP ARPC1B HSPA8 FRMD5	6.20e-05	185	163	6	3e00879466e626aa8604efecfc4678d64f54dbfc
ToppCell	facs-Bladder-nan-18m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 RIPOR2 PSAP ARPC1B HSPA8 FRMD5	6.20e-05	185	163	6	3dc5812c961ff209f197ff4cbfb90009c0537550
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	A2M ASH1L BIRC6 URB1 PRKDC POLQ	6.39e-05	186	163	6	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LCP1 GPSM3 PLS1 DKKL1 FRMD5 IQCG	6.39e-05	186	163	6	02fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L ZBTB7A UBXN4 UBXN2A PKN2 NIPBL	6.58e-05	187	163	6	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	Endothelial-A-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	A2M HSPG2 CPXM2 LAMA4 TEK DCHS1	6.58e-05	187	163	6	febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCell	LPS-IL1RA+antiTNF-Myeloid\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PADI4 RIPOR2 NAIP LCP1 FCGR2A GPSM3	6.58e-05	187	163	6	4e0bbef6ba0d1b3e1f8d900d4a9dbd41f09a7bc5
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	A2M HSPG2 CPXM2 LAMA4 TEK DCHS1	6.58e-05	187	163	6	be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCell	Monocytes-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	RIPOR2 HLA-B NAIP LCP1 ARPC1B GPSM3	6.77e-05	188	163	6	756375cf9c9cccc4fb4a7f5e4756fa3fc36a7892
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-Monocytes\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PADI4 AKNA LCP1 IGFLR1 NUP210 GPSM3	6.98e-05	189	163	6	a010f3e4da6e9bb23b0b9a7f82ad5cee4e607ecd
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPOR2 HLA-B LCP1 ARPC1B NUP210 GPSM3	6.98e-05	189	163	6	5c92516c3745ccbd480b15bb2b9077ab1d9ee5a0
ToppCell	Control-B_intermediate-6\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	FLNA PSAP HLA-B UBR4 ARPC1B FCGR2A	6.98e-05	189	163	6	11cb9a16f1de8f60af2073ed7ea6d4f41c02f299
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 LAMA4 TEK TLNRD1 DCHS1 TRIM37	6.98e-05	189	163	6	ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RIPOR2 PSAP NAIP LCP1 JARID2 FCGR2A	7.18e-05	190	163	6	57800d807785b9d539b47945a0a74631f5e88a06
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	A2M HSPG2 TEK ARPC1B TLNRD1 ITIH6	7.18e-05	190	163	6	d4aefae2d3164db6a9e953c54af0151501e9d1da
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L LARP4 ZBTB7A UBXN2A PKN2 LCOR	7.39e-05	191	163	6	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	A2M HYOU1 BIRC6 URB1 PRKDC POLQ	7.39e-05	191	163	6	9454f642c3621370fa23640b631301346b300950
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PADI4 RIPOR2 PSAP NAIP LCP1 GPSM3	7.39e-05	191	163	6	5d6ef70cc15ec5e983a953e547e40f9c06e355fb
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PADI4 RIPOR2 HLA-B LCP1 FCGR2A PRKDC	7.39e-05	191	163	6	47156e5f1d790707f42f6283104a44b33af613e5
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RIPOR2 PSAP NAIP LCP1 FCGR2A GPSM3	7.39e-05	191	163	6	1c7d31684654ca6a046d8cc816af1fdc42369c57
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RIPOR2 PSAP NAIP LCP1 FCGR2A GPSM3	7.39e-05	191	163	6	d60d81d2045c6e624bbc8b17e13a32f7921d969f
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L LARP4 ZBTB7A UBXN2A PKN2 LCOR	7.39e-05	191	163	6	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L LARP4 ZBTB7A UBXN2A PKN2 LCOR	7.39e-05	191	163	6	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PADI4 RIPOR2 NAIP LCP1 JARID2 FCGR2A	7.39e-05	191	163	6	47a2afc4102199b4bc76bd01b2967c8016186462
ToppCell	PND07\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA PSAP LRRC58 ARPC1B SLITRK6 HSPA8	7.61e-05	192	163	6	8171a60df481195c39a7f740effcae8e4deb6ca7
ToppCell	COVID-19-kidney-Myeloid\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PADI4 RIPOR2 HLA-B LCP1 FCGR2A GPSM3	7.61e-05	192	163	6	0b9d22a222f1201e375f8e55cace9ef939febae4
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	A2M HSPG2 LAMA4 ARPC1B GFRA1 SLITRK6	7.83e-05	193	163	6	e1de67ddada87229f5db0ec193a6da8745a86a64
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal-choroid_plexus/mesenchymal-like_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	A2M HSPG2 LAMA4 ARPC1B GFRA1 SLITRK6	7.83e-05	193	163	6	b6f5a85210e60798205eaf5884cdb540f549d08a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLNA SYNE1 AKNA LCP1 MXRA7 ZBTB7A	8.06e-05	194	163	6	24837a27b0041fe8c348225fa8b09b127d743603
ToppCell	Monocytes-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	PADI4 RIPOR2 HLA-B NAIP ARPC1B GPSM3	8.06e-05	194	163	6	ed14fbb3b4622798f8e02dc91bbe464a6fed8310
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PADI4 RIPOR2 HLA-B LCP1 FCGR2A GPSM3	8.06e-05	194	163	6	4eef50c38e6edb2ef2cdcd14eb50805f6cd65bc8
ToppCell	3'-Distal_airway-Immune_Myeloid\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA PSAP LCP1 ARPC1B FCGR2A SUSD1	8.29e-05	195	163	6	4df004b8ca7669a57d85c6dffef5b82b4ea1dfdf
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA PSAP LCP1 ARPC1B FCGR2A SUSD1	8.29e-05	195	163	6	9e49e59a20b1bbd6167d594c33ab6bdfe2c1ebaf
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA PSAP LCP1 ARPC1B FCGR2A SUSD1	8.29e-05	195	163	6	412a9fcf9f075d97fae254bbd89774e4b1face07
ToppCell	control-Lymphocytic-CD8_T_cells\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	FLNA HLA-B SYNE1 AKNA LCP1 MXRA7	8.29e-05	195	163	6	55b9052336cab3e769a126ecaeef267d8e7bcaa8
Disease	brain ischemia (biomarker_via_orthology)	EPOR NAIP TEK GFRA1 SLC8A3 HSPA8 HSPA9	1.17e-06	102	155	7	DOID:2316 (biomarker_via_orthology)
Disease	mitral valve prolapse (is_implicated_in)	FLNA HLA-B DCHS1	1.17e-05	9	155	3	DOID:988 (is_implicated_in)
Disease	Tinnitus, wellbeing measurement	PSAP CTC1 GATB PTK2 CAPN15 CHST3	1.20e-05	96	155	6	EFO_0007869, HP_0000360
Disease	androsterone sulfate measurement	CPXM2 BIRC6 ZBTB7A SLC51A	2.66e-05	33	155	4	EFO_0021117
Disease	Massive Hepatic Necrosis	PANX1 PRKDC	2.74e-05	2	155	2	C0001364
Disease	obsolete_red blood cell distribution width	SLC17A2 GALP LCP1 IGFLR1 AP3B1 BIRC6 PTK2 PIGQ SUSD1 NUP210 NFRKB MAST1 UBXN2A PKN2 PNPLA3 PLS1 HSPA8 MUSK FRMD5 SEC23B	2.77e-05	1347	155	20	EFO_0005192
Disease	phosphatidylcholine 36:3 measurement	KIF2B MUSK IQCG	6.18e-05	15	155	3	EFO_0010381
Disease	Spondyloepiphyseal Dysplasia	HSPG2 FLNA CHST3	7.57e-05	16	155	3	C0038015
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	HSPG2 FLNA CHST3	7.57e-05	16	155	3	C3541456
Disease	Schwartz-Jampel Syndrome, Type 1	HSPG2 FLNA CHST3	7.57e-05	16	155	3	C4551479
Disease	Schwartz-Jampel Syndrome	HSPG2 FLNA CHST3	7.57e-05	16	155	3	C0036391
Disease	Melnick-Needles Syndrome	HSPG2 FLNA CHST3	7.57e-05	16	155	3	C0025237
Disease	Van Buchem disease	HSPG2 FLNA CHST3	9.16e-05	17	155	3	C0432272
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 FLNA CHST3	1.30e-04	19	155	3	DOID:2256 (is_implicated_in)
Disease	Osteochondrodysplasias	HSPG2 FLNA CHST3	1.30e-04	19	155	3	C0029422
Disease	Dyschondroplasias	HSPG2 FLNA CHST3	1.30e-04	19	155	3	C0013366
Disease	Multiple Epiphyseal Dysplasia	HSPG2 FLNA CHST3	1.52e-04	20	155	3	C0026760
Disease	triacylglycerol 52:2 measurement	LCP1 SEPSECS CTNNA3 MUSK	2.03e-04	55	155	4	EFO_0010414
Disease	Ovarian Serous Adenocarcinoma	STK36 TEK MAST1	2.33e-04	23	155	3	C1335177
Disease	level of leukocyte immunoglobulin-like receptor subfamily B member 4 in blood serum	PSAP CHST3	2.71e-04	5	155	2	OBA_2042200
Disease	level of prosaposin in blood serum	PSAP CHST3	2.71e-04	5	155	2	OBA_2044552
Disease	Myasthenia Gravis	HLA-B MUSK	4.06e-04	6	155	2	C0026896
Disease	angiopoietin-1 receptor, soluble measurement	HLA-B TEK	4.06e-04	6	155	2	EFO_0008023
Disease	Myasthenia Gravis, Ocular	HLA-B MUSK	4.06e-04	6	155	2	C0751340
Disease	Myasthenia Gravis, Generalized	HLA-B MUSK	4.06e-04	6	155	2	C0751339
Disease	X-23641 measurement	PSTK PNPLA3	5.66e-04	7	155	2	EFO_0800854
Disease	Huntington's disease (implicated_via_orthology)	LCP1 PPARGC1A PLS1	6.31e-04	32	155	3	DOID:12858 (implicated_via_orthology)
Disease	Parkinson's disease (is_implicated_in)	A2M PPARGC1A HSPA8 HSPA9	7.00e-04	76	155	4	DOID:14330 (is_implicated_in)
Disease	Disproportionate short stature	HSPG2 FLNA EVC2 CHST3	7.36e-04	77	155	4	C0878659
Disease	leukocyte immunoglobulin-like receptor subfamily B member 4 measurement	PSAP CHST3	7.52e-04	8	155	2	EFO_0801768
Disease	Pena-Shokeir syndrome type I	SLC18A3 MUSK	7.52e-04	8	155	2	C1276035
Disease	neutropenia (is_implicated_in)	AP3B1 FCGR2A	7.52e-04	8	155	2	DOID:1227 (is_implicated_in)
Disease	Lung diseases	A2M AP3B1 ADRA2B PRKDC	7.72e-04	78	155	4	C0024115
Disease	SPINOCEREBELLAR ATAXIA 17	HYOU1 HSPA8	9.63e-04	9	155	2	C1846707
Disease	free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	HLA-B LCP1 BIRC6 SLC8A3 TYW1B PNPLA3 MUSK	1.15e-03	303	155	7	EFO_0004612, EFO_0020945
Disease	aseptic loosening, revision of total knee arthroplasty	CPXM2 KIF2B CTNNA3	1.40e-03	42	155	3	EFO_0010725, EFO_0020972
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	LCP1 PNPLA3 MUSK	1.40e-03	42	155	3	EFO_0008317, EFO_0008596, EFO_0020945
Disease	Parkinson's disease (implicated_via_orthology)	OPRL1 HIPK3 PPARGC1A HSF1 HSPA9	1.47e-03	157	155	5	DOID:14330 (implicated_via_orthology)
Disease	triacylglycerol 56:6 measurement	LCP1 PNPLA3 MUSK	1.50e-03	43	155	3	EFO_0010433
Disease	immunoglobulin isotype switching measurement	HLA-B UBR4 LAMA4	1.61e-03	44	155	3	EFO_0010128
Disease	complement C1q tumor necrosis factor-related protein 1 measurement	PSAP CHST3	1.75e-03	12	155	2	EFO_0801493
Disease	granulins measurement	PSAP CHST3	1.75e-03	12	155	2	EFO_0008141
Disease	cirrhosis of liver	HLA-B PNPLA3	2.06e-03	13	155	2	EFO_0001422
Disease	birth weight, pelvic organ prolapse	LAMA4 AP3B1 UBE3D	2.19e-03	49	155	3	EFO_0004344, EFO_0004710
Disease	Tobacco Dependence	LCP1 CHRNA3	2.39e-03	14	155	2	C0040332
Disease	Nicotine Dependence	LCP1 CHRNA3	2.39e-03	14	155	2	C0028043
Disease	Nicotine Use Disorder	LCP1 CHRNA3	2.39e-03	14	155	2	C0376384
Disease	liver neoplasm	HLA-B PNPLA3	2.75e-03	15	155	2	EFO_1001513
Disease	gamma-glutamylphenylalanine measurement	TEK CTNNA3	2.75e-03	15	155	2	EFO_0021142
Disease	level of Triacylglycerol (53:3) in blood serum	LCP1 MUSK	2.75e-03	15	155	2	OBA_2045165
Disease	high density lipoprotein cholesterol measurement, metabolic syndrome	LCP1 MUSK	2.75e-03	15	155	2	EFO_0000195, EFO_0004612
Disease	non-alcoholic fatty liver disease	SLC17A2 AKNA LCP1 PNPLA3 LMBRD1	2.80e-03	182	155	5	EFO_0003095
Disease	peripheral arterial disease	LCP1 CHRNA3 SLC8A3	2.90e-03	54	155	3	EFO_0004265
Disease	Metastatic melanoma	PTK2 MAST1 PRKDC	2.90e-03	54	155	3	C0278883
Disease	Antithrombotic agent use measurement	HLA-B LCP1 OPRL1	3.05e-03	55	155	3	EFO_0009925
Disease	ecosanoids measurement	SLC22A10 PNPLA3 MUSK	3.05e-03	55	155	3	EFO_0020044
Disease	linoleic acid measurement	HLA-B LCP1 FER1L4 PNPLA3 MUSK	3.08e-03	186	155	5	EFO_0006807
Disease	lung small cell carcinoma (is_marker_for)	CHRNA3 PTK2	3.13e-03	16	155	2	DOID:5409 (is_marker_for)
Disease	level of triacylglycerol (56:6) in blood serum	PNPLA3 MUSK	3.13e-03	16	155	2	OBA_2020007
Disease	diacylglycerol 36:2 measurement	LCP1 MUSK	3.13e-03	16	155	2	EFO_0010355
Disease	antihyperlipidemic drug use measurement	LCP1 OPRL1 PNPLA3 MUSK	3.22e-03	115	155	4	EFO_0803367
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	HLA-B LCP1 BIRC6 OPRL1 TYW1B MUSK	3.47e-03	276	155	6	EFO_0004612, EFO_0020943
Disease	omega-3 polyunsaturated fatty acid measurement	HLA-B LCP1 TYW1B MUSK	3.53e-03	118	155	4	EFO_0010119
Disease	respiratory symptom change measurement, response to placebo	PPARGC1A PKN2	3.54e-03	17	155	2	EFO_0008344, EFO_0010068
Disease	glycoprotein measurement	HLA-B ADGRV1 LCP1 PNPLA3	3.64e-03	119	155	4	EFO_0004555
Disease	free cholesterol to total lipids in medium HDL percentage	HLA-B LCP1 MUSK	3.91e-03	60	155	3	EFO_0022282
Disease	phosphatidylcholine 36:4 measurement	RIPOR2 MUSK	3.97e-03	18	155	2	EFO_0010382
Disease	diacylglycerol 36:3 measurement	LCP1 MUSK	3.97e-03	18	155	2	EFO_0020062
Disease	non-alcoholic fatty liver disease (is_implicated_in)	PPARGC1A PNPLA3	3.97e-03	18	155	2	DOID:0080208 (is_implicated_in)
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	HLA-B LCP1 PNPLA3	4.09e-03	61	155	3	EFO_0008317, EFO_0008596, EFO_0020946
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	HLA-B LCP1 OPRL1 TYW1B MUSK	4.19e-03	200	155	5	EFO_0004611, EFO_0020945
Disease	APOE carrier status, dementia	RIPOR2 SLITRK6 MUSK	4.29e-03	62	155	3	EFO_0007659, MONDO_0001627
Disease	peripheral neuropathy, response to docetaxel trihydrate	TRPC7 CTNNA3	4.42e-03	19	155	2	EFO_0003100, GO_1902519
Disease	diacylglycerol 38:5 measurement	PNPLA3 MUSK	4.42e-03	19	155	2	EFO_0020067
Disease	diacylglycerol 38:3 measurement	PNPLA3 MUSK	4.42e-03	19	155	2	EFO_0020065
Disease	angiopoietin-1 receptor measurement	HLA-B TEK	4.42e-03	19	155	2	EFO_0010600
Disease	triglycerides:total lipids ratio, high density lipoprotein cholesterol measurement	HLA-B LCP1 OPRL1 TYW1B MUSK	4.74e-03	206	155	5	EFO_0004612, EFO_0020947
Disease	coagulation factor V measurement	SUSD1 MUSK	4.90e-03	20	155	2	EFO_0008087

Protein segments in the cluster

Peptide	Gene	Start	Entry
SAAEQELLLTLPSLE	NAIP	1066	Q13075
ELLLTLPSLESLEVS	NAIP	1071	Q13075
LTTTDLAALLPEALG	BPIFB3	311	P59826
PDRLSLQLALTELET	ARHGEF10L	481	Q9HCE6
NPLLLSSTTELIEEI	ASH1L	581	Q9NR48
LPSVLLELLSQSCLI	BIRC6	4356	Q9NR09
LLLLGTLTDLSADLE	CTC1	111	Q2NKJ3
VLLLSFALIILPSIS	CREB3L3	326	Q68CJ9
LLLSLLPVARASEAE	CHRNA3	21	P32297
AVATLASETLPLLAL	ARPC1B	236	O15143
PLTVLLLLASADSQA	FCGR2A	21	P12318
LSTITLTILADNIPE	ADGRV1	3716	Q8WXG9
PIALLPLSDTLSSLV	COQ6	256	Q9Y2Z9
AADILVATLIIPFSL	ADRA2B	56	P18089
VLLPASLASTSLAIL	GLYCAM1	6	Q8IVK1
VTPSALAELLDLLDS	GATB	446	O75879
DSITCLLSELPQLSL	DNHD1	2096	Q96M86
LLEDLAVSLTVPSPL	CASP8AP2	1436	Q9UKL3
FVTLDSNIPLDLLTL	CFAP44	121	Q96MT7
LVLLLLVLLPTDASV	A2M	11	P01023
LLDSITVPVARASIL	AP3B1	486	O00203
TATPALALVLLAVTL	CPXM2	6	Q8N436
LSLPDVLRISAVLED	IQCG	56	Q9H095
DIATLLIPAITTADA	HSPG2	2006	P98160
LDIVLILTSAILLGS	GSG1L2	131	A8MUP6
LTVLVLLPLESATAL	SLC34A3	201	Q8N130
LLPLESATALLERLS	SLC34A3	206	Q8N130
PALSSEALVRVLVLD	PCDHB2	541	Q9Y5E7
EAQPTTLADAIILLT	CAPN15	946	O75808
FLSLTLSDLPVIDIL	EXO5	276	Q9H790
TLTISLLDTSNLELP	PADI4	266	Q9UM07
LRAASPIITLVALDE	NUP210	1021	Q8TEM1
LLLPSALSEQTEALI	MSH3	426	P20585
LDRETTPALLLLVEA	DCHS1	1501	Q96JQ0
SPSDSCLLLLDVLVL	PCDH20	171	Q8N6Y1
SSLLLAPALQLLLDT	SLC16A11	176	Q8NCK7
SLLSLQTELLLDLVA	GPSM3	56	Q9Y4H4
SLLLEILLLESQASL	NFRKB	381	Q6P4R8
STTVLVLRLPDLALN	CRB2	501	Q5IJ48
ILLLVEATSVLLPTD	ENTPD8	26	Q5MY95
LLLPFSIISNEILLS	LMBR1	76	Q8WVP7
IALITSALLPVDIFL	LMBRD1	56	Q9NUN5
ILELSISLPAETELT	FER1L4	1301	A9Z1Z3
IAPVLELADSSALLP	KCNT1	691	Q5JUK3
SSIALLAEAPTLPLI	BMP15	31	O95972
VLLLLLSTLVIPSAA	DKKL1	16	Q9UK85
VDTLLSPTALIDSIL	HSF1	321	Q00613
SISTSLPVLDLIDAI	PLS1	546	Q14651
ISTSLPVLDLIDAIQ	LCP1	546	P13796
VPLARSLQISEELLS	LCOR	151	Q96JN0
LVPLLELACTDTHTL	OR4C45	176	A6NMZ5
ILDTLSPRLATALSE	PNPLA3	316	Q9NST1
LILEEIFTSLARLPT	NIPBL	1451	Q6KC79
TALLSIQDLLLEELS	EVC2	986	Q86UK5
AALRAPLDLTTILVS	LINGO3	516	P0C6S8
SLDLTLILIIALGSV	PCDH10	711	Q9P2E7
PLLLISLAFAQEISI	PANX1	46	Q96RD7
PLVELACSDTSLLEL	OR6C4	181	Q8NGE1
DVTDVLLLDVTPLSL	HSPA9	431	P38646
LLLDVTPLSLGIETL	HSPA9	436	P38646
LLIDADLRITPAETL	HIPK3	506	Q9H422
PRTVLLLLSAALALT	HLA-B	6	P01889
PASLLELRALQTLSL	LRRC58	136	Q96CX6
EALPTEAQLLISSLL	MAST1	611	Q9Y2H9
LSDLALTLPTDAVSI	METTL3	86	Q86U44
EPALTATATVLLSLV	PCDHA13	656	Q9Y5I0
ANLLAVLTETLDSLP	PPARGC1A	86	Q9UBK2
LGPVELALTSILTLL	SLC51A	46	Q86UW1
LSEELIASRLVPLLL	SCYL3	281	Q8IZE3
SDSFLDTTVPLLVLI	CTNNA3	386	Q9UI47
LLVLLLSLAETPASA	GALP	11	Q9UBC7
LLLLIILTESDLDIA	FRMD5	516	Q7Z6J6
VLLADLLALSDTLAV	HYOU1	21	Q9Y4L1
RLVSAALVILSELPA	HEATR5A	1721	Q86XA9
LAALDTLNPADISLV	DNAH3	2771	Q8TD57
PLLVLVVTALSTLLS	GFRA1	446	P56159
IPINISETDLSLLTA	FLNA	1971	P21333
TSLVLLDLISEVPLR	POLQ	721	O75417
AATLAVSPLLLVTIL	GPR148	61	Q8TDV2
EASLLPLLSRELSSL	IGFLR1	231	Q9H665
ELLLAPALLEQLTCT	ABCA2	226	Q9BZC7
VLRLSLSSESELPSL	AKNA	1166	Q7Z591
SPSDLVELVARILAL	ELP3	341	Q9H9T3
LTTDPDLILEVLRSS	LARP4	166	Q71RC2
AISLLLLPEELELLS	ITIH6	996	Q6UXX5
VILADLNLSVSPFLL	IPO9	481	Q96P70
SDLDPLILTLSLILV	EPOR	246	P19235
STLLDALVLRNIEPI	KLB	176	Q86Z14
SVLLISELEALLPAR	FIGNL2	486	A6NMB9
PSVLLAVELLSLLAD	ATRIP	601	Q8WXE1
LLASTLLALLVSPAR	CREG1	16	O75629
LLLLSLGLVLAEASE	RNASE11	6	Q8TAA1
SLLELLELLLDASAL	SCNN1D	706	P51172
LELLLDASALTLVLG	SCNN1D	711	P51172
VSRLEILNVLSDSLP	PEX1	1011	O43933
IDLETILLLNPALDS	KIF2B	71	Q8N4N8
LSDLLIENTSLTVPI	FANCD2	231	Q9BXW9
LTVPILDVLSSLRLD	FANCD2	241	Q9BXW9
TALDVLLELVVLNPS	FANCD2	491	Q9BXW9
SLTDDLRLLPALTVL	LRRC40	96	Q9H9A6
LTTPRLTLSELDDII	LAMA4	541	Q16363
LLLLDVTPLSLGIET	HSPA8	391	P11142
PTLSTISALLDELRD	JARID2	1076	Q92833
SPALSSEALVRLLVL	PCDHB6	536	Q9Y5E3
FNLALADTLVLLTLP	OPRL1	91	P41146
SPSLNVSLLLTLSIL	MT-ND2	146	P03891
ESELSPFLITLILAV	TAS2R39	26	P59534
APTLADLAAVTALLL	VARS1	156	P26640
PLSAIAQLLSILTEV	SZT2	811	Q5T011
ALADAIIELQLLPAS	SZT2	2381	Q5T011
LLSLEESSELLHLVP	UTP20	571	O75691
TDPLVSLENVLLTAL	TRMT13	456	Q9NUP7
AATSSLLDIDPLILI	TRIM37	606	O94972
LVDTALLPTLAFLVD	SLC18A3	396	Q16572
VLLSLAEDVLTVSPA	SNTA1	31	Q13424
LESQLILATAEPLCL	SUPT20HL1	196	Q3ZLR7
TILRSLTDAVPLSVL	SLITRK6	596	Q9H5Y7
STEDLPEVILTLSLI	SLC9C1	11	Q4G0N8
ILPSELSLQLAEVAL	SYNE1	5391	Q8NF91
AAILSTLLAAEVIPT	SLC22A17	426	Q8WUG5
LLPFSIISNEVLLSL	LMBR1L	81	Q6UX01
LLLPLLILCTVSVAS	IGLV3-27	6	P01718
ILSEDALLRISIPLD	SLC22A10	66	Q63ZE4
ILEQLAELLPSVSSV	RABGGTA	551	Q92696
LRTLLATVDETIPLL	PTK2	961	Q05397
PICLLLASLLSLVSA	PIGQ	211	Q9BRB3
PAISLADSTDLRVLL	STRIP1	206	Q5VSL9
ELTISALSLALLVPV	SLC26A10	201	Q8NG04
SVLLSLPAARLLEDL	TELO2	776	Q9Y4R8
ASLGDLITLSILALV	SLC41A3	226	Q96GZ6
AEVLATLPSLAIQSL	CCT8L1P	141	A6NM43
AEVLATLPSLAIQSL	CCT8L2	141	Q96SF2
LAGTLSLSLTAPLEL	SLC25A43	21	Q8WUT9
SLSLTAPLELATVLA	SLC25A43	26	Q8WUT9
IIIEELSLVAASPTL	PKN2	291	Q16513
ALLPTLAVDELDTVL	URB1	1186	O60287
LVSQILDRAEPLLSS	RIPOR2	861	Q9Y4F9
PVLLDSSSILADRIL	SEC23B	636	Q15437
VSSSALALIIPALLE	SLC36A3	401	Q495N2
LSDQPLLTSDLLSLL	STK36	1071	Q9NRP7
IASLTLLEISDLNEL	MRPL12	71	P52815
LESQLILATAEPLCL	SUPT20HL2	196	P0C7V6
STAAVLLADILPTLV	CLN3	96	Q13286
ELLEDPNISASLILS	CIP2A	61	Q8TCG1
DPALILAENASLLSL	CHST3	66	Q7LGC8
SGLLEISAVPLSDLL	C12orf29	176	Q8N999
TLLLVSELGLDSEVL	PPOX	71	P50336
LRALSSELPVVISLT	SUSD1	566	Q6UWL2
SLEVTDLLLTALENP	PSTK	236	Q8IV42
LTLPSATCLELLLIL	UBE3D	351	Q7Z6J8
LVLSSNVPLLALEFL	TXNDC2	41	Q86VQ3
LLISSLLTLFTPLAA	SLC17A2	126	O00624
SLATALPVLRLLDET	UBXN2A	216	P68543
LVADLLLLSSEARPV	TLNRD1	46	Q9H1K6
TSLLSLDLIEPLLQL	TMCO6	376	Q96DC7
LILINSLPLVSDAET	TEK	26	Q02763
SSILSILLEEVSPEL	PSAP	366	P07602
ERLVSLLLNPAVLST	PRKDC	1526	P78527
ELLVLLAALLATVSG	TMED2	6	Q15363
LVLDLAQARSTLVLP	VWA5B2	106	Q8N398
LILPESLSLLTFEDV	ZNF75D	226	P51815
ASPSLDVLITLLSLG	SEPSECS	316	Q9HD40
RASTALLLPILLTTE	TOGARAM1	231	Q9Y4F4
SPTLLLAEAVLTYLE	LCMT2	181	O60294
IRTLLPLLLESSTES	UBR4	1311	Q5T4S7
LDLELAPSASVVLLP	UBXN4	381	Q92575
LLAALASLLLPESAA	TYRO3	26	Q06418
LAEAVTSLDLPVAII	TYW1B	51	Q6NUM6
DILSAARLLEIPAVS	ZBTB7A	106	O95365
LELSPAQLLLLLASE	UBR5	2421	O95071
LSLSSEDPVLTALEL	TRPC7	231	Q9HCX4
LGSSAPEILLSLIEV	SLC8A3	141	P57103
ELLAALPALATALAL	MXRA7	6	P84157
SAAVTLTTLPSELLL	MUSK	531	O15146