Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainLRRC37_N

LRRC37A LRRC37A3 LRRC37A2

2.63e-084363IPR032754
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

2.63e-084363PF14914
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

2.63e-084363IPR029423
DomainLRRC37

LRRC37A LRRC37A3 LRRC37A2

2.63e-084363PF15779
DomainLRRC37A/B-like

LRRC37A LRRC37A3 LRRC37A2

2.63e-084363IPR015753
DomainSAM_2

STIM2 SAMD11

3.10e-0343362PF07647
DomainLRR_8

LRRC37A LRRC37A3 LRRC37A2

4.31e-03171363PF13855
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A LRRC37A3 LRRC37A2

4.81e-09438322419166
Pubmed

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.

RIN3 CR1 ABCA7 INPP5D

7.79e-083738424162737
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A LRRC37A3 LRRC37A2

1.44e-071038323064749
Pubmed

CR1, ABCA7, and APOE genes affect the features of cognitive impairment in Alzheimer's disease.

CR1 ABCA7

3.48e-06338224530172
Pubmed

Functional genomics identifies drivers of medulloblastoma dissemination.

CDK20 LHX1

3.48e-06338222875024
Pubmed

Validating GWAS Variants from Microglial Genes Implicated in Alzheimer's Disease.

CR1 ABCA7

6.96e-06438228477215
Pubmed

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

CR1 ABCA7

3.24e-05838221460840
Pubmed

Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells.

LHX1 POU3F1

4.16e-05938225868900
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

AP1G2 DGLUCY NBR1 PDZD11 USP19

5.05e-0537138515747579
Pubmed

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

CR1 ABCA7

6.35e-051138221460841
Pubmed

Leukaemia disease genes: large-scale cloning and pathway predictions.

BHLHE41 ZFP36

6.35e-051138210610183
Pubmed

Cyclin-dependent kinases: a family portrait.

CDK20 CDK12

7.62e-051238219884882
Pubmed

Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon.

LHX1 POU3F1

1.38e-041638219890917
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF629 ABLIM1 IL17RA ZNF319 USP42 CDK12 WDR33

2.87e-04120338729180619
Pubmed

Transcriptional control of motor pool formation and motor circuit connectivity by the LIM-HD protein Isl2.

LHX1 POU3F1

3.43e-042538237869988
Pubmed

TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling.

LHX1 TET3

4.32e-042838227760115
Pubmed

Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.

RIN3 TET3

5.65e-043238221546767
Pubmed

WW domains provide a platform for the assembly of multiprotein networks.

RPRD2 CDK12 WDR33

6.41e-0415438316055720
Pubmed

Global control of motor neuron topography mediated by the repressive actions of a single hox gene.

LHX1 POU3F1

7.15e-043638220826310
Pubmed

Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.

ABLIM1 NBR1

9.74e-04423827584044
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ABLIM1 ZNF319 TET3 USP19

9.96e-0440738412693553
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

RPRD2 STIM2 WDR33

1.01e-0318038335198878
Cytoband17q21.31

LRRC37A NBR1 LRRC37A2

4.43e-058238317q21.31
GeneFamilyCyclin dependent kinases

CDK20 CDK12

8.44e-0426302496
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL10RA IL17RA

2.20e-0342302602
GeneFamilyUbiquitin specific peptidases

USP42 USP19

3.88e-0356302366
GeneFamilySterile alpha motif domain containing

STIM2 SAMD11

9.33e-0388302760
CoexpressionMORI_PRE_BI_LYMPHOCYTE_DN

IL10RA ABLIM1 NBR1 ZFP36

5.49e-0680384M6455
CoexpressionMORI_PRE_BI_LYMPHOCYTE_DN

IL10RA ABLIM1 NBR1 ZFP36

6.99e-0685384MM590
CoexpressionWANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP

IL10RA AP1G2 RPRD2 LRRC37A ABCA7 LRRC37A2

1.98e-05392386M2131
CoexpressionRODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN

BHLHE41 MMRN2 ABLIM1 ZNF319 FGD4 WDR33 LRRC37A2

1.40e-04807387M16651
CoexpressionGSE22886_UNSTIM_VS_IL2_STIM_NKCELL_UP

IL10RA DGLUCY LRRC37A3 WDR33

1.83e-04196384M4530
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_MICROGLIA

IL10RA BHLHE41 IL17RA ZFP36 INPP5D

1.89e-04371385M39022
CoexpressionGSE45382_UNTREATED_VS_TGFB_TREATED_MACROPHAGES_UP

DGLUCY IL17RA PDZD11 INPP5D

1.91e-04198384M9803
CoexpressionGSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP

C11orf21 HRG IL17RA USP19

1.91e-04198384M5299
CoexpressionGSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP

IL10RA BHLHE41 POU3F1 PDZD11

1.94e-04199384M7756
CoexpressionGSE3982_EOSINOPHIL_VS_MAST_CELL_UP

IL10RA RIN3 ABCA7 USP19

1.94e-04199384M5397
CoexpressionGSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP

IL10RA C11orf21 TET3 ZFP36

1.94e-04199384M4460
CoexpressionGSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_UP

IL10RA RIN3 ZFP36 INPP5D

1.98e-04200384M9895
ToppCellLV-08._Macrophage|LV / Chamber and Cluster_Paper

IL10RA RIN3 IL17RA CR1 TET3 INPP5D

1.38e-081923867be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

IL10RA RIN3 IL17RA CR1 TET3 INPP5D

1.56e-08196386cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|lung / Disease (COVID-19 only), tissue and cell type

IL10RA IL17RA CR1 FGD4 TET3 INPP5D

1.60e-081973863896729740d151f0eb845f1961c7b969bfbdd28d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal|GW26 / Sample Type, Dataset, Time_group, and Cell type.

IL10RA BHLHE41 RIN3 IL17RA ZFP36 INPP5D

1.76e-0820038616caefcc5bdca82d904462c6fd0ffa80d96fa474
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal-BMP_responsible_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

IL10RA BHLHE41 RIN3 IL17RA ZFP36 INPP5D

1.76e-08200386cd0d69f973ca3204b500d12031b403a1f4593431
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL10RA RIN3 CR1 TET3 INPP5D

5.56e-071893852586f4088721c5debec86c2b211b739fd33713eb
ToppCellLV-08._Macrophage|World / Chamber and Cluster_Paper

IL10RA RIN3 CR1 TET3 INPP5D

5.86e-07191385e7a0bc46ba9ba772636a583f3387748418e18832
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

C11orf21 RIN3 IL17RA CR1 TET3

5.86e-0719138547a2afc4102199b4bc76bd01b2967c8016186462
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

IL10RA RIN3 CR1 TET3 INPP5D

6.01e-07192385a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellChildren_(3_yrs)-Immune-monocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

IL10RA RIN3 IL17RA CR1 INPP5D

6.17e-0719338558e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

IL10RA RIN3 CR1 TET3 INPP5D

6.17e-0719338512bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellLA-08._Macrophage|World / Chamber and Cluster_Paper

IL10RA RIN3 CR1 TET3 INPP5D

6.33e-07194385c1805572bcc11b1cd29083329d7b5911489fb758
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

RIN3 CR1 FGD4 TET3 INPP5D

6.33e-07194385ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

IL10RA RIN3 CR1 TET3 INPP5D

6.49e-071953855e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellCOVID-19-Myeloid-Monocytes|COVID-19 / group, cell type (main and fine annotations)

IL10RA RIN3 IL17RA FGD4 TET3

6.66e-0719638504d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCellFetal_29-31_weeks-Immune-monocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IL10RA RIN3 IL17RA CR1 INPP5D

6.83e-071973858b9a88fb671d5c2b25d291c851e2b8a478f2610c
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL10RA IL17RA CR1 TET3 INPP5D

6.83e-07197385e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL10RA RIN3 IL17RA CR1 INPP5D

7.00e-07198385ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IL10RA BHLHE41 RIN3 FGD4 INPP5D

7.18e-07199385b0a906586e58009f5ed9272fc29ba28e49c85ee6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IL10RA BHLHE41 FGD4 ZFP36 INPP5D

7.18e-07199385e245851a5bddf56f7e13a7fb7c5fda2fd275dae3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-BMP_responsible_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 RIN3 IL17RA ZFP36 INPP5D

7.36e-0720038526251ed8c7fa7e87973d6f59bd398c88ad025395
ToppCellChildren_(3_yrs)-Immune-monocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

IL10RA RIN3 CR1 TET3 INPP5D

7.36e-07200385881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 RIN3 IL17RA ZFP36 INPP5D

7.36e-07200385fe22f7c97f4e37dfa7881d0f1d9245c1237d873b
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MMRN2 LRRC37A TET3 LRRC37A2

1.14e-051643841aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Endothelial-endothelial_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN2 HRG RIN3 ZNF319

1.41e-051733842a5ea28c65dd4ee03ba3d0bfe0c819b1d583f8da
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Endothelial|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN2 HRG RIN3 ZNF319

1.41e-051733846a7e4fa2d9d00f50decc89b535d8a68ec96de58a
ToppCell18-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

C11orf21 TET3 ABCA7 INPP5D

1.47e-05175384cc476b4244442418b8f21721a82a36209b556b36
ToppCell18-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

C11orf21 TET3 ABCA7 INPP5D

1.47e-051753847130b816e0c02309c161d8e9ad7cb4bc2469e251
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL10RA C11orf21 RIN3 IL17RA

1.61e-05179384ce95b601bf17ae8167d382a105384b9e65e9407f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA C11orf21 RIN3 INPP5D

1.68e-051813848657d35cd3dff6c89d0fde67d7e7e81e1d6c8884
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RIN3 INPP5D RECQL4

1.91e-0518738473931a5ea73799095daff100b5f18853c57c74dc
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

WDR81 MMRN2 ADAM33 ZFP36

1.95e-05188384c90669b51e1902fe7726555290c91c92a911df83
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RIN3 IL17RA INPP5D

2.03e-051903847c402aa47f1bd7decacc366c1ed1a37e39b95c73
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RIN3 CR1 INPP5D

2.08e-05191384baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCellRA-08._Macrophage|World / Chamber and Cluster_Paper

RIN3 FGD4 TET3 INPP5D

2.16e-051933845fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RIN3 CR1 INPP5D

2.21e-051943841dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RIN3 TET3 INPP5D

2.21e-05194384c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RIN3 CR1 INPP5D

2.21e-051943840866ab6792cee274a71991d5c37a37f574ff446e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA IL17RA CR1 INPP5D

2.25e-0519538491a3c439f10c03c5d51d904f512b6a08040edc76
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RIN3 CR1 INPP5D

2.25e-051953842d485373bfd9bb4bb9236bf0b31d03e132c8018f
ToppCellChildren_(3_yrs)-Immune-monocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

IL10RA RIN3 IL17RA INPP5D

2.25e-0519538481a28289eda1a8a1a31b7357106f64ac5000e172
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IL10RA BHLHE41 IL17RA INPP5D

2.25e-05195384b6bf75669f267ecdc96818c7022db852e37a9fe1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RIN3 CR1 INPP5D

2.25e-0519538434a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCellcellseq-Immune-Immune_Myeloid-iMON|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL10RA RIN3 IL17RA CR1

2.30e-051963845842d6fa0c066815d7d8c7e59b192bfc72960707
ToppCellAdult-Immune-monocyte|Adult / Lineage, Cell type, age group and donor

IL10RA RIN3 IL17RA INPP5D

2.30e-051963843ef193c5180de3137daf886492e74fc574bc9767
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RIN3 TET3 INPP5D

2.30e-05196384cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RIN3 CR1 INPP5D

2.30e-051963844370473693d2dd4a8c451a4c477eb79baa33ae12
ToppCellAdult-Immune-monocyte-D122|Adult / Lineage, Cell type, age group and donor

IL10RA RIN3 IL17RA INPP5D

2.30e-0519638416b0acb6157534938ca83d4e909471e33a7d3c52
ToppCellcellseq-Immune-Immune_Myeloid-iMON-iMON|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL10RA RIN3 IL17RA CR1

2.30e-051963848608be3c3e7fd776c5f2fae207cd0b801e138349
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-gdT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL10RA C11orf21 RIN3 INPP5D

2.34e-05197384b803c07072a7860497d07a3be358a28a24359cbf
ToppCellFetal_29-31_weeks-Immune-monocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IL10RA RIN3 IL17RA INPP5D

2.34e-0519738448a8169a4d33c6a68d66bcd936861c75cb4b60ef
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RIN3 CR1 INPP5D

2.39e-0519838496883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Myeloid-Microglia|GW16 / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 IL17RA ZFP36 INPP5D

2.39e-05198384901cd39cb84f1907f2f5d27221979c854bd3b40e
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Myeloid|GW16 / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 IL17RA ZFP36 INPP5D

2.39e-05198384cc292aa8518d5ef8940e2327f2f07d584a996d90
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Myeloid-Microglia|GW26 / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 IL17RA ZFP36 INPP5D

2.39e-05198384c0d33629438504a1545e07f0e5af2e76f50fd55b
ToppCellFetal_29-31_weeks-Immune|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IL10RA RIN3 CR1 INPP5D

2.39e-051983845dff131356b8c22743bd27b2b21f86ee6e4a0a0d
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Myeloid|GW26 / Sample Type, Dataset, Time_group, and Cell type.

BHLHE41 IL17RA ZFP36 INPP5D

2.39e-051983842b93995f66c7352acc25d6c71d025b847881dacd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL10RA RIN3 IL17RA INPP5D

2.39e-05198384623f9d64c9e800d2d7f623392bf2f22b563f0249
ToppCellImmune-monocyte|World / Lineage, Cell type, age group and donor

IL10RA RIN3 IL17RA INPP5D

2.39e-05198384d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IL10RA BHLHE41 FGD4 INPP5D

2.44e-05199384e7faf7d0cb43cf93149c446e5f718f84fa85477c
ToppCellParenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL10RA RIN3 CR1 INPP5D

2.44e-05199384ac866ae110967c5867ff4601939b79861d43df54
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

BHLHE41 IL17RA FGD4 INPP5D

2.48e-0520038421bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellTracheal-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL10RA RIN3 CR1 INPP5D

2.48e-05200384ad7ae5106141669b353800fece833b3cd5bdccee
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL10RA RIN3 CR1 INPP5D

2.48e-052003848872d5fa101d413fb43b4231d476878678543035
ToppCellParenchymal-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL10RA RIN3 CR1 INPP5D

2.48e-05200384fd72fe6565e2f4885481991492d58c323ab1ad40
ToppCellmild-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IL17RA FGD4 TET3 ZFP36

2.48e-05200384934c2efc780318c66d667ca75be0de350361d351
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

BHLHE41 IL17RA FGD4 INPP5D

2.48e-05200384a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellTracheal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IL10RA C11orf21 RIN3 INPP5D

2.48e-0520038472e1cc0b222df3ab76164524676e91628e237995
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

BHLHE41 IL17RA FGD4 INPP5D

2.48e-05200384dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

BHLHE41 IL17RA FGD4 INPP5D

2.48e-05200384a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

BHLHE41 IL17RA FGD4 INPP5D

2.48e-052003843bba5219453322198e8fdb0921d5f8c403598751
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

BHLHE41 IL17RA FGD4 INPP5D

2.48e-0520038433036d21c1c82109284473a515c4f890b33fdd5c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IL10RA WDR81 RIN3 INPP5D

2.48e-0520038480e0483d5ab0c6213aae0ec62619f57e6ec0e4c2
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

IL10RA RIN3 CR1 INPP5D

2.48e-05200384fc061de0db2e8b5ca47f5e2a1e861018e7f1b582
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Npw|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

POU3F1 ADAM33 IL17RA

1.22e-04113383165de4316059222f33d1e51aeff4554037c0b937
ToppCelldroplet-Liver-nan-3m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA RPRD2 INPP5D

1.72e-0412738339fa20a55de3af1a62ab5dfa4877879db3935ac2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BHLHE41 IL17RA FGD4

2.81e-041503836c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCelldroplet-Lung-nan-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA IL17RA ZFP36

2.87e-04151383c743dc8758416a4f562d60c8fd2df7e659ab6951
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BHLHE41 IL17RA INPP5D

2.87e-041513832f9b3e14c2fa6e2b1976ca6ab2031b63bf5e3e64
ToppCelldroplet-Lung-nan-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA IL17RA ZFP36

2.98e-04153383f6ef14d949107c08cb3690e26ec91e194cb43518
ToppCelldroplet-Lung-nan-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA IL17RA ZFP36

2.98e-041533836dcab3d50ab50051955204dc4e4a64c1ca855bcd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF629 LHX1 AP1G2

3.10e-041553838b524c65fa5c901f70c7caae4ec7fd2859eaf227
ToppCellprimary_visual_cortex-Non-neuronal-macrophage-Macrophage-Microglia_Siglech|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IL10RA ZFP36 INPP5D

3.10e-04155383f59ca572556c17c606604da1b0331710d4751e54
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

C11orf21 ABLIM1 STIM2

3.10e-041553837aba8ef53c9170ad8ed955c904c8991097ab1e32
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF629 LHX1 AP1G2

3.10e-041553837fe8b8c0c8a9e3190cfd52d3934509e6780e1717
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA AP1G2 IL17RA

3.28e-04158383b0508a600994090c6aafd8d779437190a33ad821
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL17RA FGD4 INPP5D

3.28e-04158383f61ebe3a316e4259387cd9da83707f15e6473cae
ToppCellfacs-Lung-EPCAM-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA AP1G2 IL17RA

3.28e-04158383a816cc095452308d06f87b77467e2a8c6361fd2a
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

POU3F1 ADAM33 IL17RA

3.34e-04159383a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL10RA IL17RA INPP5D

3.46e-04161383d1f2e5245c7c247b684f48f9f877e149a3ee7c06
ToppCellfacs-Lung-EPCAM-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA IL17RA FGD4

3.52e-04162383484ea4ac40de672dcbd2583a52cb7f385c918814
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA IL17RA FGD4

3.52e-04162383bba144ac5332bab9eba2ccf599703c781a7f88f1
ToppCellfacs-Lung-nan-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA IL17RA FGD4

3.52e-041623833fd6aaf0fbaffc7ab38aa25e46c37ef511e1e704
ToppCellfacs-Lung-nan-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA IL17RA FGD4

3.52e-041623838134f73eb76693f4f1845f643042fdc1e81c274c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAM33 PDZD11 RECQL4

3.65e-041643834ef776d1bab4103d42d3a4f22cdfb49e8d2bc5a0
ToppCellfacs-Lung-nan-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA IL17RA FGD4

3.72e-04165383720649f330382ea2a68c64a5344160a048afb8f1
ToppCellfacs-Trachea-nan-18m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA IL17RA INPP5D

3.78e-041663837f8b4cf63c3e292ae421f111edaa4572717f4db1
ToppCelldroplet-Lung-LUNG-1m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA IL17RA ZFP36

3.78e-04166383dd5944101ef58a9a29aa3eb5c17690119572b8f1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HRG RIN3 INPP5D

3.78e-0416638363dc58864268b4e7779e4c45155022556fc634f9
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RA IL17RA ZFP36

3.78e-041663838e5e8de51b4dacdadaa5a08279df30b5c7ed3628
Diseasefamily history of Alzheimer’s disease

CR1 ABCA7 INPP5D

9.78e-0571373EFO_0009268
DiseaseAcute Confusional Senile Dementia

CR1 ABCA7 INPP5D

2.62e-0499373C0546126
DiseasePresenile dementia

CR1 ABCA7 INPP5D

2.62e-0499373C0011265
DiseaseAlzheimer's Disease, Focal Onset

CR1 ABCA7 INPP5D

2.62e-0499373C0750900
DiseaseAlzheimer Disease, Early Onset

CR1 ABCA7 INPP5D

2.62e-0499373C0750901
DiseaseAlzheimer Disease, Late Onset

CR1 ABCA7 INPP5D

2.62e-0499373C0494463
Diseaserheumatoid arthritis

ZNF629 C11orf21 RIN3 TET3 CDK12

2.66e-04462375EFO_0000685
DiseaseFamilial Alzheimer Disease (FAD)

CR1 ABCA7 INPP5D

2.70e-04100373C0276496
DiseaseAlzheimer's Disease

CR1 ABCA7 INPP5D

2.78e-04101373C0002395
DiseaseAlzheimer disease, family history of Alzheimer’s disease

CR1 ABCA7 INPP5D

4.50e-04119373EFO_0009268, MONDO_0004975
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

ZNF629 C11orf21 TET3

1.26e-03170373EFO_0000685, EFO_0007791, EFO_0007837
Diseaseprimary ovarian insufficiency (implicated_via_orthology)

USP42 WDR33

1.53e-0346372DOID:5426 (implicated_via_orthology)
Diseaseeosinophil count

C11orf21 AP1G2 RIN3 IL17RA ZNF319 TET3 INPP5D

2.22e-031488377EFO_0004842
Diseaseeosinophil percentage of leukocytes

RIN3 IL17RA TET3 ABCA7 INPP5D

2.27e-03746375EFO_0007991
DiseaseAlzheimer disease, gastroesophageal reflux disease

ZNF629 RIN3 INPP5D

2.91e-03228373EFO_0003948, MONDO_0004975
DiseaseAlzheimer disease

WDR81 CR1 ABCA7 INPP5D

3.10e-03485374MONDO_0004975
Diseasebasophil count, eosinophil count

C11orf21 RIN3 INPP5D

3.41e-03241373EFO_0004842, EFO_0005090
DiseaseMammary Neoplasms, Human

HRG ADAM33 LRRC37A LRRC37A2

4.11e-03525374C1257931
DiseaseMammary Carcinoma, Human

HRG ADAM33 LRRC37A LRRC37A2

4.11e-03525374C4704874
DiseaseMammary Neoplasms

HRG ADAM33 LRRC37A LRRC37A2

4.17e-03527374C1458155
DiseaseBreast Carcinoma

HRG ADAM33 LRRC37A LRRC37A2

4.48e-03538374C0678222
Diseasemonocyte count

C11orf21 ZNF777 RIN3 IL17RA FGD4 INPP5D

5.60e-031320376EFO_0005091
Diseaselate-onset Alzheimers disease

CR1 ABCA7 INPP5D

5.81e-03292373EFO_1001870
DiseaseEczema

C11orf21 RIN3 INPP5D

6.85e-03310373HP_0000964
Diseaseneutrophil count

RPRD2 RIN3 IL17RA WDR33 ABCA7 INPP5D

6.98e-031382376EFO_0004833

Protein segments in the cluster

PeptideGeneStartEntry
GPPHIHDFHVDRPLE

CDK20

316

Q8IZL9
SQPEAEPPGHLPHEH

CDK12

1306

Q9NYV4
EPPGHLPHEHQALRP

CDK12

1311

Q9NYV4
FVAHPQDPHHPSEKP

ABLIM1

81

O14639
HEVAPLGAPHPQHPH

BHLHE41

436

Q9C0J9
DVQHPPHLDPSPGGA

AP1G2

636

O75843
PLDPENSHEPSSHPE

ADAM33

776

Q9BZ11
HPPLEHHECHFPNKP

ABCA7

46

Q8IZY2
VHHLPKPIPDGDPNH

IL17RA

161

Q96F46
PPEHHEVTVSPPGHH

LRRC37A3

386

O60309
PDERDHSHGPPLPQG

HRG

301

P04196
PPEHHEVTVSPPGHH

LRRC37A2

386

A6NM11
PPEHHEVTVSPPGHH

LRRC37A

386

A6NMS7
PPRPAEHLEPSHDAG

MMRN2

671

Q9H8L6
PPAWIPPHERVHHPD

PDZD11

21

Q5EBL8
GPNEHPATLDDHPEP

FGD4

746

Q96M96
HEAQLEPSPPPHLGA

POU3F1

196

Q03052
GLEHPLPGHHPSSEA

LHX1

326

P48742
ALGHHSPPEPEVPGE

IL10RA

421

Q13651
QPPPEILHGEHTLSH

CR1

1651

P17927
PHPESHVTHNPSPTE

GFY

241

I3L273
THFNHEPPEETDGPP

DGLUCY

341

Q7Z3D6
EHHLPPSPLEHGTPF

RPRD2

1191

Q5VT52
HVTPHAPGPPDHPNQ

RIN3

321

Q8TB24
QVHEGHHVVDEAPPP

NBR1

81

Q14596
EPDLHGPAPVPTNLH

RECQL4

661

O94761
ELPHHGKHRPEEGPP

INPP5D

1166

Q92835
EDPPWHDPPHHLPSH

SAMD11

221

Q96NU1
PPATAHEPVDHPALH

C11orf21

71

Q9P2W6
PEHHPGHGDRLSPGE

USP42

996

Q9H9J4
PPRAGHSEHHPDLGP

USP19

1221

O94966
HPQHTPHSLPSPDPD

STIM2

546

Q9P246
HNPSEDLAAPGHPPV

ZFP36

166

P26651
PSQAVPTDAHHPTPH

TET3

1341

O43151
PQHHAEPPPALAEHT

ZNF319

21

Q9P2F9
GHEHFRDTPRPDHPP

WDR33

1191

Q9C0J8
RDTPRPDHPPHDGHS

WDR33

1196

Q9C0J8
PDHPPHDGHSPASRE

WDR33

1201

Q9C0J8
GHSNPLDHQIPLDPP

ZNF629

81

Q9UEG4
SPHHQEAPVHSPEAP

ZNF777

121

Q9ULD5
GGEPPHVPHHISDVL

WDR81

431

Q562E7