Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	DNER FLG2 STAB1 SNED1 FBLN1 MEGF6 MEGF8 OTOF TKT LOXL2 LRP4 ADGRE5 MYL10 FBN3 NOTCH4	7.62e-06	749	104	15	GO:0005509
GeneOntologyMolecularFunction	Notch binding	DNER SNED1 NOTCH4	3.67e-04	27	104	3	GO:0005112
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	4.13e-04	120	104	5	GO:0004222
GeneOntologyMolecularFunction	endopeptidase activity	PCSK5 HGFAC TMPRSS11E ADAMTS10 ADAMTS6 ADAMTS9 PCSK6 ADAMTS16 ADAMTS20	4.14e-04	430	104	9	GO:0004175
GeneOntologyMolecularFunction	polysaccharide binding	CLEC18A CLEC18B CLEC18C	5.55e-04	31	104	3	GO:0030247
GeneOntologyBiologicalProcess	extracellular matrix organization	CARMIL2 ADAMTSL3 ADAMTS10 FBLN1 ADAMTS6 ADAMTS9 LOXL2 WNT3A ADAMTS16 ADAMTS20	1.93e-05	377	103	10	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	CARMIL2 ADAMTSL3 ADAMTS10 FBLN1 ADAMTS6 ADAMTS9 LOXL2 WNT3A ADAMTS16 ADAMTS20	1.97e-05	378	103	10	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	CARMIL2 ADAMTSL3 ADAMTS10 FBLN1 ADAMTS6 ADAMTS9 LOXL2 WNT3A ADAMTS16 ADAMTS20	2.02e-05	379	103	10	GO:0045229
GeneOntologyBiologicalProcess	animal organ morphogenesis	ERBB4 RPGRIP1L HYAL1 WNT6 NTN3 GATA6 NDP GATA5 ZFPM1 IRX4 LHX9 ENAM GRXCR2 MEGF8 ADAMTS9 WNT3A ADAMTS16 LRP4	5.26e-05	1269	103	18	GO:0009887
GeneOntologyBiologicalProcess	tube development	PCSK5 FNDC3B RPGRIP1L THSD7A HYAL1 WNT6 GATA6 CARD10 NDP GATA5 STAB1 MEGF8 ADAMTS9 LOXL2 WNT3A SCAPER ADAMTS16 COBL NOTCH4	5.86e-05	1402	103	19	GO:0035295
GeneOntologyBiologicalProcess	pattern specification process	PCSK5 ERBB4 RPGRIP1L WNT6 GATA5 IRX4 MEGF8 WNT3A PCSK6 LRP4 COBL	6.42e-05	526	103	11	GO:0007389
GeneOntologyBiologicalProcess	circulatory system development	PCSK5 ERBB4 RPGRIP1L THSD7A HYAL1 SPEG GATA6 CARD10 NDP GATA5 ZFPM1 IRX4 STAB1 MEGF8 ADAMTS6 ADAMTS9 LOXL2 WNT3A NOTCH4	8.53e-05	1442	103	19	GO:0072359
GeneOntologyCellularComponent	extracellular matrix	WNT6 NTN3 NDP ADAMTSL3 SSPOP ADAMTS10 ENAM SNED1 FBLN1 FCGBP MEGF6 ADAMTS6 ADAMTS9 LOXL2 PCSK6 ADAMTS16 ADAMTS20 FBN3	2.68e-09	656	102	18	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	WNT6 NTN3 NDP ADAMTSL3 SSPOP ADAMTS10 ENAM SNED1 FBLN1 FCGBP MEGF6 ADAMTS6 ADAMTS9 LOXL2 PCSK6 ADAMTS16 ADAMTS20 FBN3	2.81e-09	658	102	18	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	NTN3 NDP SSPOP ADAMTS10 FBLN1 MEGF6 ADAMTS9 LOXL2 PCSK6 ADAMTS20	2.66e-04	530	102	10	GO:0062023
MousePheno	abnormal heart atrium morphology	PCSK5 RPGRIP1L SPEG GATA5 IRX4 FBLN1 MEGF8 PCSK6 PLAGL1	7.56e-06	232	81	9	MP:0003105
MousePheno	atrial septal defect	PCSK5 RPGRIP1L FBLN1 MEGF8 PCSK6 PLAGL1	1.16e-05	88	81	6	MP:0010403
MousePheno	abnormal interatrial septum morphology	PCSK5 RPGRIP1L FBLN1 MEGF8 PCSK6 PLAGL1	3.56e-05	107	81	6	MP:0000282
MousePheno	muscular ventricular septal defect	RPGRIP1L FBLN1 MEGF8 ADAMTS6 PLAGL1	8.22e-05	77	81	5	MP:0010420
MousePheno	abnormal interventricular septum muscular part morphology	RPGRIP1L FBLN1 MEGF8 ADAMTS6 PLAGL1	9.29e-05	79	81	5	MP:0010498
MousePheno	abnormal heart right atrium morphology	RPGRIP1L SPEG GATA5 IRX4	1.30e-04	45	81	4	MP:0003922
MousePheno	abnormal interventricular septum morphology	PCSK5 RPGRIP1L GATA5 FBLN1 MEGF8 ADAMTS6 LOXL2 PCSK6 PLAGL1	1.57e-04	342	81	9	MP:0000281
MousePheno	absent sacral vertebrae	PCSK5 WNT3A	1.97e-04	4	81	2	MP:0004656
MousePheno	dextrocardia	PCSK5 RPGRIP1L MEGF8 PCSK6	2.13e-04	51	81	4	MP:0000644
MousePheno	double outlet right ventricle	PCSK5 RPGRIP1L FBLN1 MEGF8 ADAMTS6 PCSK6	2.31e-04	150	81	6	MP:0000284
MousePheno	abnormal glossopharyngeal nerve morphology	ERBB4 FBLN1 MEGF8	2.67e-04	22	81	3	MP:0001073
Domain	EGF	PCSK5 HGFAC CLEC18A CLEC18B HYAL1 DNER CLEC18C STAB1 SNED1 FBLN1 FCGBP MEGF6 MEGF8 PCSK6 LRP4 ADGRE5 FBN3 NOTCH4	4.80e-16	235	101	18	SM00181
Domain	EGF-like_dom	PCSK5 HGFAC CLEC18A CLEC18B HYAL1 DNER CLEC18C STAB1 SNED1 FBLN1 FCGBP MEGF6 MEGF8 PCSK6 LRP4 ADGRE5 FBN3 NOTCH4	1.33e-15	249	101	18	IPR000742
Domain	EGF_1	HGFAC CLEC18A CLEC18B HYAL1 NTN3 DNER CLEC18C SSPOP ITGB7 STAB1 SNED1 FBLN1 MEGF6 MEGF8 LRP4 FBN3 NOTCH4	3.36e-14	255	101	17	PS00022
Domain	EGF_2	HGFAC CLEC18A CLEC18B HYAL1 NTN3 DNER CLEC18C SSPOP ITGB7 STAB1 SNED1 FBLN1 MEGF6 MEGF8 LRP4 FBN3 NOTCH4	6.31e-14	265	101	17	PS01186
Domain	Growth_fac_rcpt_	PCSK5 ELAPOR2 ERBB4 NTN3 DNER STAB1 FBLN1 MEGF6 MEGF8 PCSK6 LRP4 ADGRE5 FBN3 NOTCH4	1.22e-13	156	101	14	IPR009030
Domain	EGF_3	HGFAC CLEC18A CLEC18B HYAL1 DNER CLEC18C SSPOP STAB1 SNED1 FBLN1 MEGF6 MEGF8 LRP4 ADGRE5 FBN3 NOTCH4	1.47e-13	235	101	16	PS50026
Domain	EGF-like_CS	HGFAC CLEC18A CLEC18B HYAL1 NTN3 DNER CLEC18C ITGB7 STAB1 SNED1 FBLN1 MEGF6 MEGF8 LRP4 FBN3 NOTCH4	7.40e-13	261	101	16	IPR013032
Domain	PLAC	PCSK5 ADAMTSL3 ADAMTS10 ADAMTS6 PCSK6 ADAMTS16	6.24e-11	14	101	6	PF08686
Domain	PLAC	PCSK5 ADAMTSL3 ADAMTS10 ADAMTS6 PCSK6 ADAMTS16	5.51e-10	19	101	6	PS50900
Domain	PLAC	PCSK5 ADAMTSL3 ADAMTS10 ADAMTS6 PCSK6 ADAMTS16	5.51e-10	19	101	6	IPR010909
Domain	EGF_CA	DNER STAB1 SNED1 FBLN1 MEGF6 MEGF8 LRP4 ADGRE5 FBN3 NOTCH4	1.13e-09	122	101	10	SM00179
Domain	EGF-like_Ca-bd_dom	DNER STAB1 SNED1 FBLN1 MEGF6 MEGF8 LRP4 ADGRE5 FBN3 NOTCH4	1.33e-09	124	101	10	IPR001881
Domain	TSP_1	THSD7A ADAMTSL3 SSPOP ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	1.67e-09	63	101	8	PF00090
Domain	TSP1	THSD7A ADAMTSL3 SSPOP ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	2.16e-09	65	101	8	SM00209
Domain	TSP1_rpt	THSD7A ADAMTSL3 SSPOP ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	2.16e-09	65	101	8	IPR000884
Domain	TSP1	THSD7A ADAMTSL3 SSPOP ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	2.16e-09	65	101	8	PS50092
Domain	EGF_Ca-bd_CS	DNER SNED1 FBLN1 MEGF6 MEGF8 LRP4 ADGRE5 FBN3 NOTCH4	2.65e-09	97	101	9	IPR018097
Domain	Peptidase_M12B_ADAM-TS	ADAMTSL3 ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	2.68e-09	24	101	6	IPR013273
Domain	EGF_CA	DNER SNED1 FBLN1 MEGF6 MEGF8 LRP4 ADGRE5 FBN3 NOTCH4	3.19e-09	99	101	9	PS01187
Domain	ASX_HYDROXYL	DNER SNED1 FBLN1 MEGF6 MEGF8 LRP4 ADGRE5 FBN3 NOTCH4	3.48e-09	100	101	9	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	DNER SNED1 FBLN1 MEGF6 MEGF8 LRP4 ADGRE5 FBN3 NOTCH4	5.86e-09	106	101	9	IPR000152
Domain	ADAM_spacer1	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	1.30e-07	23	101	5	IPR010294
Domain	ADAM_spacer1	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	1.30e-07	23	101	5	PF05986
Domain	hEGF	DNER SNED1 MEGF6 FBN3 NOTCH4	3.73e-07	28	101	5	PF12661
Domain	EGF	HGFAC DNER STAB1 SNED1 MEGF6 LRP4 FBN3 NOTCH4	4.10e-07	126	101	8	PF00008
Domain	EGF_CA	FBLN1 MEGF6 MEGF8 LRP4 ADGRE5 FBN3 NOTCH4	4.15e-07	86	101	7	PF07645
Domain	-	CLEC18A CLEC18B CLEC18C R3HDML	1.05e-06	15	101	4	3.40.33.10
Domain	CAP	CLEC18A CLEC18B CLEC18C R3HDML	1.05e-06	15	101	4	PF00188
Domain	CAP_domain	CLEC18A CLEC18B CLEC18C R3HDML	1.05e-06	15	101	4	IPR014044
Domain	SCP	CLEC18A CLEC18B CLEC18C R3HDML	1.05e-06	15	101	4	SM00198
Domain	Allrgn_V5/Tpx1	CLEC18A CLEC18B CLEC18C R3HDML	1.05e-06	15	101	4	IPR001283
Domain	Peptidase_M12B_N	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	2.08e-06	39	101	5	IPR002870
Domain	Pep_M12B_propep	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	2.08e-06	39	101	5	PF01562
Domain	DISINTEGRIN_1	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	2.37e-06	40	101	5	PS00427
Domain	Reprolysin	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	2.37e-06	40	101	5	PF01421
Domain	ADAM_MEPRO	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	2.37e-06	40	101	5	PS50215
Domain	DISINTEGRIN_2	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	2.37e-06	40	101	5	PS50214
Domain	Peptidase_M12B	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	2.37e-06	40	101	5	IPR001590
Domain	Disintegrin_dom	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	2.69e-06	41	101	5	IPR001762
Domain	GF_recep_IV	PCSK5 ERBB4 PCSK6	3.03e-06	6	101	3	PF14843
Domain	GF_recep_IV	PCSK5 ERBB4 PCSK6	3.03e-06	6	101	3	IPR032778
Domain	Fol_N	DNER SNED1 FCGBP	2.45e-05	11	101	3	IPR003645
Domain	FOLN	DNER SNED1 FCGBP	2.45e-05	11	101	3	SM00274
Domain	Pept_M12B_GON-ADAMTSs	ADAMTS9 ADAMTS20	2.90e-05	2	101	2	IPR012314
Domain	GON	ADAMTS9 ADAMTS20	2.90e-05	2	101	2	PF08685
Domain	GON	ADAMTS9 ADAMTS20	2.90e-05	2	101	2	PS51046
Domain	Laminin_EGF	NTN3 STAB1 MEGF6 MEGF8	3.71e-05	35	101	4	PF00053
Domain	EGF_Lam	NTN3 STAB1 MEGF6 MEGF8	3.71e-05	35	101	4	SM00180
Domain	Laminin_EGF	NTN3 STAB1 MEGF6 MEGF8	5.16e-05	38	101	4	IPR002049
Domain	MetalloPept_cat_dom	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	7.74e-05	81	101	5	IPR024079
Domain	-	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	7.74e-05	81	101	5	3.40.390.10
Domain	GATA_N	GATA6 GATA5	8.66e-05	3	101	2	IPR008013
Domain	GATA-N	GATA6 GATA5	8.66e-05	3	101	2	PF05349
Domain	Furin_repeat	PCSK5 ERBB4 PCSK6	1.18e-04	18	101	3	IPR006212
Domain	FU	PCSK5 ERBB4 PCSK6	1.18e-04	18	101	3	SM00261
Domain	ZINC_PROTEASE	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	1.91e-04	98	101	5	PS00142
Domain	EPHD	PHF7 G2E3 KMT2D	2.19e-04	22	101	3	PS51805
Domain	EGF_extracell	DNER ITGB7 STAB1 MEGF6	3.11e-04	60	101	4	IPR013111
Domain	EGF_2	DNER ITGB7 STAB1 MEGF6	3.11e-04	60	101	4	PF07974
Domain	cEGF	FBLN1 LRP4 FBN3	3.65e-04	26	101	3	IPR026823
Domain	cEGF	FBLN1 LRP4 FBN3	3.65e-04	26	101	3	PF12662
Domain	Peptidase_S8_Asp-AS	PCSK5 PCSK6	4.28e-04	6	101	2	IPR023827
Domain	ZnF_U1	ZNF407 SCAPER ZFHX2	5.06e-04	29	101	3	SM00451
Domain	Znf_U1	ZNF407 SCAPER ZFHX2	5.06e-04	29	101	3	IPR003604
Domain	EGF_LAM_2	NTN3 STAB1 MEGF8	5.60e-04	30	101	3	PS50027
Domain	EGF_LAM_1	NTN3 STAB1 MEGF8	5.60e-04	30	101	3	PS01248
Domain	PrprotnconvertsP	PCSK5 PCSK6	5.97e-04	7	101	2	IPR002884
Domain	P_proprotein	PCSK5 PCSK6	5.97e-04	7	101	2	PF01483
Domain	S8_pro-domain	PCSK5 PCSK6	5.97e-04	7	101	2	IPR032815
Domain	-	PCSK5 PCSK6	5.97e-04	7	101	2	3.30.70.850
Domain	S8_pro-domain	PCSK5 PCSK6	5.97e-04	7	101	2	PF16470
Domain	Peptidase_S8_His-AS	PCSK5 PCSK6	1.02e-03	9	101	2	IPR022398
Domain	Integin_beta_N	ITGB7 MEGF8	1.02e-03	9	101	2	IPR033760
Domain	Peptidase_S8_Ser-AS	PCSK5 PCSK6	1.02e-03	9	101	2	IPR023828
Domain	PSI_integrin	ITGB7 MEGF8	1.02e-03	9	101	2	PF17205
Domain	TYR_PHOSPHATASE_1	DUSP2 DUSP22 PTPN13 PTPRA	1.22e-03	86	101	4	PS00383
Domain	Peptidase_S8_subtilisin-rel	PCSK5 PCSK6	1.27e-03	10	101	2	IPR015500
Domain	SUBTILASE_ASP	PCSK5 PCSK6	1.27e-03	10	101	2	PS00136
Domain	SUBTILASE_HIS	PCSK5 PCSK6	1.27e-03	10	101	2	PS00137
Domain	SUBTILASE_SER	PCSK5 PCSK6	1.27e-03	10	101	2	PS00138
Domain	TYR_PHOSPHATASE_2	DUSP2 DUSP22 PTPN13 PTPRA	1.27e-03	87	101	4	PS50056
Domain	TYR_PHOSPHATASE_dom	DUSP2 DUSP22 PTPN13 PTPRA	1.27e-03	87	101	4	IPR000387
Domain	-	PCSK5 PCSK6	1.54e-03	11	101	2	3.40.50.200
Domain	Peptidase_S8/S53_dom	PCSK5 PCSK6	1.54e-03	11	101	2	IPR000209
Domain	Peptidase_S8	PCSK5 PCSK6	1.54e-03	11	101	2	PF00082
Domain	-	DUSP2 DUSP22 PTPN13 PTPRA	1.56e-03	92	101	4	3.90.190.10
Domain	C-type_lectin_CS	CLEC18A CLEC18B CLEC18C	1.62e-03	43	101	3	IPR018378
Domain	Galactose-bd-like	PCSK5 NTN3 SSPOP PCSK6	1.69e-03	94	101	4	IPR008979
Domain	EGF_3	STAB1 MEGF8	1.84e-03	12	101	2	PF12947
Domain	TIL	SSPOP FCGBP	1.84e-03	12	101	2	PF01826
Domain	ZnF_GATA	GATA6 GATA5	1.84e-03	12	101	2	SM00401
Domain	EGF_dom	STAB1 MEGF8	1.84e-03	12	101	2	IPR024731
Domain	C8	SSPOP FCGBP	1.84e-03	12	101	2	PF08742
Domain	-	CLEC18A CLEC18B CLEC18C STAB1	1.90e-03	97	101	4	3.10.100.10
Domain	Prot-tyrosine_phosphatase-like	DUSP2 DUSP22 PTPN13 PTPRA	2.05e-03	99	101	4	IPR029021
Domain	C-type_lectin-like/link	CLEC18A CLEC18B CLEC18C STAB1	2.05e-03	99	101	4	IPR016186
Domain	Unchr_dom_Cys-rich	SSPOP FCGBP	2.17e-03	13	101	2	IPR014853
Domain	C8	SSPOP FCGBP	2.17e-03	13	101	2	SM00832
Domain	TIL_dom	SSPOP FCGBP	2.53e-03	14	101	2	IPR002919
Domain	CTDL_fold	CLEC18A CLEC18B CLEC18C STAB1	2.72e-03	107	101	4	IPR016187
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD7A ADAMTSL3 SSPOP ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	1.18e-11	39	69	8	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD7A ADAMTSL3 SSPOP ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	1.18e-11	39	69	8	MM15165
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	THSD7A ADAMTSL3 SSPOP ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20 NOTCH4	3.68e-11	68	69	9	M27303
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	THSD7A ADAMTSL3 SSPOP ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20 NOTCH4	2.98e-08	143	69	9	M27275
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD7A ADAMTSL3 SSPOP ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	5.57e-08	109	69	8	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD7A ADAMTSL3 SSPOP ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	6.43e-08	111	69	8	M27416
Pathway	REACTOME_DISEASES_OF_METABOLISM	THSD7A HYAL1 ADAMTSL3 SSPOP ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20 NOTCH4	3.49e-07	250	69	10	M27554
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	ITGB7 FBLN1 ADAMTS9 LOXL2 ADAMTS16 LRP4 FBN3	6.43e-04	300	69	7	M610
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	THSD7A ADAMTSL3 SSPOP ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	7.51e-11	75	105	8	20637190
Pubmed	Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity.	CLEC18A CLEC18B CLEC18C	2.67e-08	3	105	3	26170455
Pubmed	The C-type lectin-like domain superfamily.	CLEC18A CLEC18B CLEC18C	2.67e-08	3	105	3	16336259
Pubmed	Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.	CLEC18A CLEC18B CLEC18C	2.67e-08	3	105	3	33603190
Pubmed	The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation.	CLEC18A CLEC18B CLEC18C	1.07e-07	4	105	3	16709836
Pubmed	Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation.	ERBB4 FBLN1 ADAMTS9 ADAMTS20	1.81e-07	17	105	4	22183742
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	PCSK5 CARD10 FBLN1 MEGF6 MEGF8 PCSK6	1.64e-06	118	105	6	21078624
Pubmed	Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.	MEGF6 MEGF8 LRP4	2.22e-06	9	105	3	9693030
Pubmed	ADAMTS: a novel family of extracellular matrix proteases.	ADAMTS10 ADAMTS6 ADAMTS9	3.16e-06	10	105	3	11167130
Pubmed	Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.	HYAL1 IRX4 FBLN1 ADAMTS9	5.35e-06	38	105	4	18267097
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS10 ADAMTS9 ADAMTS20	5.77e-06	12	105	3	25770910
Pubmed	Homozygosity mapping of a Weill-Marchesani syndrome locus to chromosome 19p13.3-p13.2.	ADAMTS10 FBN3	9.03e-06	2	105	2	11941487
Pubmed	Cell-surface processing of extracellular human immunodeficiency virus type 1 Vpr by proprotein convertases.	PCSK5 PCSK6	9.03e-06	2	105	2	18061232
Pubmed	Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.	ADAMTS9 ADAMTS20	9.03e-06	2	105	2	12514189
Pubmed	Identification of an isoform with an extremely large Cys-rich region of PC6, a Kex2-like processing endoprotease.	PCSK5 PCSK6	9.03e-06	2	105	2	8335106
Pubmed	Upregulated lnc‑HRK‑2:1 prompts nucleus pulposus cell senescence in intervertebral disc degeneration.	HRK ST8SIA5	9.03e-06	2	105	2	33174041
Pubmed	Abnormal Peyer patch development and B-cell gut homing drive IgA deficiency in Kabuki syndrome.	ITGB7 KMT2D	9.03e-06	2	105	2	31816409
Pubmed	ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions.	ADAMTS10 ADAMTS6	9.03e-06	2	105	2	27779234
Pubmed	Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4.	PCSK5 PCSK6	9.03e-06	2	105	2	8468318
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	IQCN ITGB7 IRX4 SNED1 PTPN13 PTPRA	1.26e-05	168	105	6	30631154
Pubmed	The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.	WNT6 GATA6 WNT3A PCSK6 NOTCH4	1.37e-05	100	105	5	24859004
Pubmed	ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.	DPYSL2 ADAMTS9 ADAMTS16	1.46e-05	16	105	3	30579834
Pubmed	The interaction of LOXL2 with GATA6 induces VEGFA expression and angiogenesis in cholangiocarcinoma.	GATA6 LOXL2	2.70e-05	3	105	2	31322171
Pubmed	Perception of differentiation cues by GATA factors in primitive endoderm lineage determination of mouse embryonic stem cells.	GATA6 GATA5	2.70e-05	3	105	2	16162334
Pubmed	A new Adamts9 conditional mouse allele identifies its non-redundant role in interdigital web regression.	ADAMTS9 ADAMTS20	2.70e-05	3	105	2	24753090
Pubmed	Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases.	PCSK5 PCSK6	2.70e-05	3	105	2	8670066
Pubmed	Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation.	GATA6 GATA5	2.70e-05	3	105	2	9566909
Pubmed	Maturation of HIV envelope glycoprotein precursors by cellular endoproteases.	PCSK5 PCSK6	2.70e-05	3	105	2	11063880
Pubmed	Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate.	ADAMTS9 ADAMTS20	2.70e-05	3	105	2	37169079
Pubmed	Function of GATA factors in the adult mouse liver.	GATA6 ZFPM1	2.70e-05	3	105	2	24367609
Pubmed	GATA6 and FOXA2 regulate Wnt6 expression during extraembryonic endoderm formation.	WNT6 GATA6	2.70e-05	3	105	2	22607194
Pubmed	GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development.	GATA6 GATA5	2.70e-05	3	105	2	9119112
Pubmed	ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression.	FBLN1 ADAMTS9 ADAMTS20	2.94e-05	20	105	3	19922873
Pubmed	Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse.	GATA6 GATA5 IRX4	2.94e-05	20	105	3	11245568
Pubmed	Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells.	WNT6 WNT3A LRP4	3.42e-05	21	105	3	19806668
Pubmed	The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium.	WNT6 GATA6 WNT3A	3.42e-05	21	105	3	11914369
Pubmed	GATA6 Regulates Aortic Valve Remodeling, and Its Haploinsufficiency Leads to Right-Left Type Bicuspid Aortic Valve.	GATA6 FBLN1 ADAMTS9	4.53e-05	23	105	3	29567669
Pubmed	Loss of Gata5 in mice leads to bicuspid aortic valve.	GATA6 GATA5 NOTCH4	5.17e-05	24	105	3	21633169
Pubmed	CDMP1/GDF5 has specific processing requirements that restrict its action to joint surfaces.	PCSK5 PCSK6	5.40e-05	4	105	2	16829522
Pubmed	Friend of GATA and GATA-6 modulate the transcriptional up-regulation of hepcidin in hepatocytes during inflammation.	GATA6 ZFPM1	5.40e-05	4	105	2	24179092
Pubmed	Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases.	PCSK5 PCSK6	5.40e-05	4	105	2	8615794
Pubmed	Neurotrophin secretion: current facts and future prospects.	PCSK5 PCSK6	5.40e-05	4	105	2	12787574
Pubmed	Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.	ADAMTS9 ADAMTS16	5.40e-05	4	105	2	16507336
Pubmed	Lung Krüppel-like factor contains an autoinhibitory domain that regulates its transcriptional activation by binding WWP1, an E3 ubiquitin ligase.	GATA6 GATA5	5.40e-05	4	105	2	11375995
Pubmed	Wnt2 is a direct downstream target of GATA6 during early cardiogenesis.	GATA6 GATA5	5.40e-05	4	105	2	16621466
Pubmed	BMP-mediated induction of GATA4/5/6 blocks somitic responsiveness to SHH.	GATA6 GATA5	5.40e-05	4	105	2	25294942
Pubmed	The proprotein convertases furin and PACE4 play a significant role in tumor progression.	PCSK5 PCSK6	5.40e-05	4	105	2	10900462
Pubmed	GATA- and Smad1-dependent enhancers in the Smad7 gene differentially interpret bone morphogenetic protein concentrations.	GATA6 GATA5	5.40e-05	4	105	2	12944489
Pubmed	Canonical Wnt signalling induces satellite-cell proliferation during adult skeletal muscle regeneration.	WNT6 WNT3A	5.40e-05	4	105	2	18697834
Pubmed	Retroviral envelope glycoprotein processing: structural investigation of the cleavage site.	PCSK5 PCSK6	5.40e-05	4	105	2	9521771
Pubmed	GATA6 is a crucial regulator of Shh in the limb bud.	GATA6 GATA5 ZFPM1	6.61e-05	26	105	3	24415953
Pubmed	Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure.	ADAMTS6 ADAMTS16	8.97e-05	5	105	2	29625437
Pubmed	A role for WNT proteins in induction of dermomyotome.	WNT6 WNT3A	8.97e-05	5	105	2	9356179
Pubmed	Genome-wide association study identifies two susceptibility loci for osteosarcoma.	TASOR2 ADAMTS6	8.97e-05	5	105	2	23727862
Pubmed	Common variants at 12q14 and 12q24 are associated with hippocampal volume.	HRK MSRB3	8.97e-05	5	105	2	22504421
Pubmed	ADAMTS9 and ADAMTS20 are differentially affected by loss of B3GLCT in mouse model of Peters plus syndrome.	ADAMTS9 ADAMTS20	8.97e-05	5	105	2	31600785
Pubmed	Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7.	PCSK5 PCSK6	8.97e-05	5	105	2	18664504
Pubmed	Processing of prothyrotropin-releasing hormone by the family of prohormone convertases.	PCSK5 PCSK6	8.97e-05	5	105	2	9242664
Pubmed	Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates.	PCSK5 PCSK6	8.97e-05	5	105	2	11380615
Pubmed	Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchymal stem cells.	ADAMTS9 ADAMTS16	8.97e-05	5	105	2	22562232
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	RALGDS SPEG G2E3 ADAMTS9 KLHL8	1.05e-04	153	105	5	10718198
Pubmed	NOTCH maintains developmental cardiac gene network through WNT5A.	WNT6 IRX4 WNT3A	1.24e-04	32	105	3	30347193
Pubmed	The zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expression.	GATA6 GATA5	1.34e-04	6	105	2	15539431
Pubmed	Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties.	WNT6 WNT3A	1.34e-04	6	105	2	7556445
Pubmed	Proteolytic cleavage of versican during cardiac cushion morphogenesis.	FBLN1 ADAMTS9	1.34e-04	6	105	2	16691565
Pubmed	Identification of the paired basic convertases implicated in HIV gp160 processing based on in vitro assays and expression in CD4(+) cell lines.	PCSK5 PCSK6	1.34e-04	6	105	2	8940009
Pubmed	Murine subtilisin-like proteinase SPC6 is expressed during embryonic implantation, somitogenesis, and skeletal formation.	PCSK5 PCSK6	1.34e-04	6	105	2	9291583
Pubmed	The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases.	PCSK5 PCSK6	1.34e-04	6	105	2	16135528
Pubmed	Amyotrophic Lateral Sclerosis Overview	ERBB4 SETX C9orf72	1.37e-04	33	105	3	20301623
Pubmed	WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis.	WNT6 WNT3A LRP4	1.63e-04	35	105	3	30940800
Pubmed	Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element.	GATA6 GATA5	1.88e-04	7	105	2	15987774
Pubmed	WNT-3a modulates platelet function by regulating small GTPase activity.	RALGDS WNT3A	1.88e-04	7	105	2	22705156
Pubmed	Proteolytic processing in the secretory pathway.	PCSK5 PCSK6	1.88e-04	7	105	2	10409610
Pubmed	The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.	PCSK5 PCSK6	1.88e-04	7	105	2	7819324
Pubmed	GATA factors and androgen receptor collaborate to transcriptionally activate the Rhox5 homeobox gene in Sertoli cells.	GATA6 GATA5	1.88e-04	7	105	2	18212046
Pubmed	Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling.	CLEC18A CLEC18B CLEC18C	1.93e-04	37	105	3	22432025
Pubmed	Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis.	WNT6 ZFPM1 WNT3A	1.93e-04	37	105	3	18800919
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	PCSK5 MEGF8 ADAMTS6 PCSK6	2.46e-04	100	105	4	25807483
Pubmed	Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human.	PCSK5 PCSK6	2.50e-04	8	105	2	7782070
Pubmed	Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.	PCSK5 PCSK6	2.50e-04	8	105	2	9885250
Pubmed	Cellular localization and role of prohormone convertases in the processing of pro-melanin concentrating hormone in mammals.	PCSK5 PCSK6	2.50e-04	8	105	2	10037747
Pubmed	Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation.	ADAMTS9 ADAMTS20	2.50e-04	8	105	2	21041365
Pubmed	The secreted metalloprotease ADAMTS20 is required for melanoblast survival.	ADAMTS9 ADAMTS20	2.50e-04	8	105	2	18454205
Pubmed	Gata6 restricts Isl1 to the posterior of nascent hindlimb buds through Isl1 cis-regulatory modules.	GATA6 GATA5	2.50e-04	8	105	2	29197504
Pubmed	The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer.	GATA6 GATA5	2.50e-04	8	105	2	14662776
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	DPYSL2 DNER WDR25 MSRB3 FBLN1 TXNDC5 MEGF8 LOXL2 SCAPER RNFT1 LRP4 ADGRE5	2.77e-04	1201	105	12	35696571
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	WNT6 GATA6 GATA5 KIF20A WNT3A LRP4 NOTCH4	3.11e-04	424	105	7	21731673
Pubmed	Regulation of BMP-dependent chondrogenesis in early limb mesenchyme by TGFbeta signals.	GATA6 GATA5	3.21e-04	9	105	2	20501701
Pubmed	The activation and physiological functions of the proprotein convertases.	PCSK5 PCSK6	3.21e-04	9	105	2	18343183
Pubmed	Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.	FBLN1 MEGF6	3.21e-04	9	105	2	12122015
Pubmed	The prohormone theory and the proprotein convertases: it is all about serendipity.	PCSK5 PCSK6	3.21e-04	9	105	2	21805236
Pubmed	The proprotein convertases, 20 years later.	PCSK5 PCSK6	3.21e-04	9	105	2	21805237
Pubmed	The biology and therapeutic targeting of the proprotein convertases.	PCSK5 PCSK6	3.21e-04	9	105	2	22679642
Pubmed	Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo.	GATA6 GATA5	3.21e-04	9	105	2	9738004
Pubmed	The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions.	PCSK5 PCSK6	3.21e-04	9	105	2	23775089
Pubmed	SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.	PCSK5 PCSK6	3.21e-04	9	105	2	8698813
Pubmed	Lmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hem.	LHX9 WNT3A	3.21e-04	9	105	2	20498066
Pubmed	Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis.	GATA6 GATA5	3.21e-04	9	105	2	10364163
Pubmed	Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds.	WNT6 WNT3A	4.00e-04	10	105	2	8275860
Pubmed	Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.	PCSK5 PCSK6	4.00e-04	10	105	2	16163737
Interaction	CYSRT1 interactions	PCSK5 CLEC18A RALGDS KRTAP13-3 CCDC187 CARD10 GATA5 WDR25 IQCN ADAMTSL3 ZNF835 ZFHX2	7.76e-06	511	99	12	int:CYSRT1
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS10 ADAMTS6 ADAMTS9 ADAMTS16 ADAMTS20	1.11e-08	19	74	5	50
GeneFamily	Proprotein convertase subtilisin/kexin family	PCSK5 PCSK6	5.84e-04	9	74	2	973
GeneFamily	C-type lectin domain family	CLEC18A CLEC18B CLEC18C	9.38e-04	47	74	3	494
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	GATA6 GATA5	1.68e-03	15	74	2	82
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF354A ZNF618 ZNF316 ZNF407 ZFPM1 ZNF835 SCAPER ZFHX2 PLAGL1	2.57e-03	718	74	9	28
GeneFamily	Wnt family\|Endogenous ligands	WNT6 WNT3A	2.70e-03	19	74	2	360
Coexpression	NABA_MATRISOME	PCSK5 HGFAC CLEC18A CLEC18B HYAL1 WNT6 NTN3 CLEC18C FLG2 ADAMTSL3 SSPOP ADAMTS10 SNED1 FBLN1 MEGF6 MEGF8 ADAMTS6 ADAMTS9 LOXL2 WNT3A PCSK6 ADAMTS16 ADAMTS20 FBN3	1.88e-12	1026	105	24	M5889
Coexpression	NABA_MATRISOME	PCSK5 HGFAC CLEC18A CLEC18B HYAL1 WNT6 NTN3 CLEC18C FLG2 ADAMTSL3 SSPOP ADAMTS10 SNED1 FBLN1 MEGF6 MEGF8 ADAMTS6 ADAMTS9 LOXL2 WNT3A PCSK6 ADAMTS16 ADAMTS20	9.72e-12	1008	105	23	MM17056
Coexpression	NABA_MATRISOME_ASSOCIATED	PCSK5 HGFAC CLEC18A CLEC18B HYAL1 WNT6 CLEC18C FLG2 ADAMTSL3 ADAMTS10 MEGF6 MEGF8 ADAMTS6 ADAMTS9 LOXL2 WNT3A PCSK6 ADAMTS16 ADAMTS20	1.05e-10	738	105	19	MM17058
Coexpression	NABA_MATRISOME_ASSOCIATED	PCSK5 HGFAC CLEC18A CLEC18B HYAL1 WNT6 CLEC18C FLG2 ADAMTSL3 ADAMTS10 MEGF6 MEGF8 ADAMTS6 ADAMTS9 LOXL2 WNT3A PCSK6 ADAMTS16 ADAMTS20	1.41e-10	751	105	19	M5885
Coexpression	NABA_ECM_REGULATORS	PCSK5 HYAL1 ADAMTSL3 ADAMTS10 ADAMTS6 ADAMTS9 LOXL2 PCSK6 ADAMTS16 ADAMTS20	4.28e-08	238	105	10	M3468
Coexpression	NABA_ECM_REGULATORS	PCSK5 HYAL1 ADAMTSL3 ADAMTS10 ADAMTS6 ADAMTS9 LOXL2 PCSK6 ADAMTS16 ADAMTS20	5.01e-08	242	105	10	MM17062
Coexpression	CUI_TCF21_TARGETS_2_DN	FNDC3B DPYSL2 THSD7A SPEG CARD10 DCAF5 PREX2 MSRB3 LOXL2 RNFT1 ADAMTS16 AGFG1 ADGRE5 NOTCH4	8.03e-06	854	105	14	M1533
Coexpression	CUI_TCF21_TARGETS_2_DN	FNDC3B DPYSL2 THSD7A SPEG CARD10 DCAF5 PREX2 MSRB3 LOXL2 RNFT1 ADAMTS16 AGFG1 ADGRE5 NOTCH4	1.25e-05	888	105	14	MM1018
Coexpression	HOLLERN_SQUAMOUS_BREAST_TUMOR	SLC46A2 HYAL1 KRTAP13-3 WNT6 GATA6 IRX4 LRP4	1.86e-05	204	105	7	MM966
Coexpression	HOLLERN_SQUAMOUS_BREAST_TUMOR	SLC46A2 HYAL1 WNT6 GATA6 IRX4 LRP4	7.11e-05	173	105	6	M650
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_GRIA2_POS_ARTERIAL_ENDO_CELL	PCSK5 THSD7A GATA6 PREX2 ADAMTS6	1.01e-04	115	105	5	M45752
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MID_AIRWAY_SMC_2_CELL	SPEG DUSP2 TACC2 MSRB3 ADAMTS6 ADGRE5	1.16e-04	189	105	6	M45678
Coexpression	GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_DN	SETX WNT6 DUSP2 ITGB7 STAB1 OTOF	1.37e-04	195	105	6	M5142
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MYL4_POS_SMC_CELL	SPEG TACC2 MSRB3 ADAMTS6 FBN3	1.45e-04	124	105	5	M45673
Coexpression	GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_DN	RALGDS DPYSL2 DUSP2 GATA5 TXNDC5 TAS1R1	1.57e-04	200	105	6	M5980
Coexpression	GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_DN	RALGDS SETX ZNF354A PTPN13 ADAMTS6 TAS1R1	1.57e-04	200	105	6	M2917
Coexpression	ZENG_GU_ICB_CONTROL_METAGENE_31_PRECICTIVE_ICB_RESISTANCE	WNT6 ZNF316 CCDC187 IRX4 PCSK6 ADAMTS20	1.62e-04	201	105	6	MM17086
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5	CLEC18A ERBB4 CLEC18B WNT6 NTN3 GATA6 CLEC18C GATA5 LHX9 ADAMTS9 WNT3A	4.24e-06	416	100	11	ratio_EB_vs_SC_1000_K5
CoexpressionAtlas	JC_hmvEC_top-relative-expression-ranked_1000_k-means-cluster#4	ELAPOR2 CARD10 ADAMTSL3 STAB1 SNED1 TXNDC5 OTOF ADAMTS6 LOXL2 NOTCH4	3.43e-05	428	100	10	JC_hmvEC_1000_K4
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000_k-means-cluster#4	CLEC18A CLEC18B WNT6 DNER CLEC18C GATA5 LHX9 WNT3A ADAMTS20 FBN3	3.78e-05	433	100	10	Arv_EB-LF_1000_K4
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#3	ERBB4 CLEC18B WNT6 GATA5 LHX9 ADAMTS9 WNT3A	5.13e-05	204	100	7	ratio_EB_vs_SC_500_K3
CoexpressionAtlas	DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#1_top-relative-expression-ranked_200	G2E3 LHX9 ADAMTS9	6.57e-05	17	100	3	gudmap_developingGonad_e12.5_testes_k1_200
CoexpressionAtlas	ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_100	CLEC18A CLEC18B WNT6 CLEC18C ADAMTS9	1.11e-04	100	100	5	PCBC_ratio_ECTO_vs_SC_100
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_500	CLEC18A CLEC18B WNT6 DNER GATA5 LHX9 WNT3A ADAMTS16 ADAMTS20 FBN3	1.17e-04	496	100	10	PCBC_EB_500
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500	ERBB4 CLEC18B WNT6 GATA6 GATA5 LHX9 MSRB3 ADAMTS9 WNT3A PLAGL1	1.21e-04	498	100	10	PCBC_ratio_EB_vs_SC_500
CoexpressionAtlas	Ectoderm Differentiated Cells-method_NA_vs_Ectoderm Differentiated Cells-method_plasmid-Confounder_removed-fold2.0_adjp0.05	CLEC18A CLEC18B CLEC18C WNT3A LRP4	1.22e-04	102	100	5	PCBC_ratio_ECTO_from-ESC_vs_ECTO_from-plasmid_cfr-2X-p05
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3	HGFAC CLEC18A ERBB4 CLEC18B WNT6 NTN3 DNER CLEC18C GATA5 SSPOP LHX9 ADAMTS6 ADAMTS9 WNT3A PLAGL1	1.80e-04	1094	100	15	ratio_EB_vs_SC_2500_K3
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000	CLEC18A ERBB4 THSD7A CLEC18B WNT6 NTN3 GATA6 CLEC18C GATA5 LHX9 MSRB3 ADAMTS9 WNT3A PLAGL1	2.29e-04	994	100	14	PCBC_ratio_EB_vs_SC_1000
CoexpressionAtlas	ECTO blastocyst_vs_ECTO cord blood-Confounder_removed-fold2.0_adjp0.05	CLEC18A CLEC18B CLEC18C FBLN1 ADAMTS9 FBN3	2.74e-04	189	100	6	PCBC_ratio_ECTO blastocyst_vs_ECTO cord blood_cfr-2X-p05
CoexpressionAtlas	gudmap_RNAseq_e15.5_Podocytes_2500_K0	THSD7A SPEG DUSP2 NTN3 CARD10 GATA5 R3HDML STAB1 SNED1 FBLN1 ADAMTS9 PTRH1 ADAMTS16 PLAGL1 NOTCH4	2.88e-04	1143	100	15	gudmap_RNAseq_e15.5_Podocytes_2500_K0
CoexpressionAtlas	ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#1	CLEC18A CLEC18B WNT6 CLEC18C SSPOP ADAMTS9 WNT3A	3.54e-04	279	100	7	ratio_ECTO_vs_SC_500_K1
CoexpressionAtlas	ratio_induced-Ectoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#3	CLEC18A CLEC18B WNT6 CLEC18C CAMK1G SSPOP LHX9 ADAMTS9 WNT3A	3.85e-04	471	100	9	ratio_ECTO_vs_SC_1000_K3
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	DPYSL2 RPGRIP1L ZNF618 GATA6 LHX9 ADAMTS9 TKT PCSK6 ADAMTS16 ADGRE5 KLHL8 C9orf72	3.92e-04	803	100	12	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_1000
CoexpressionAtlas	Ectoderm Differentiated Cells-reprogram_NA_vs_Ectoderm Differentiated Cells-reprogram_OSKM-L-Confounder_removed-fold2.0_adjp0.05	CLEC18A CLEC18B CLEC18C WNT3A	3.93e-04	73	100	4	PCBC_ratio_ECTO_from-ESC_vs_ECTO_from-OSKM-L_cfr-2X-p05
CoexpressionAtlas	Ectoderm Differentiated Cells-method_NA_vs_Ectoderm Differentiated Cells-method_mRNA-Confounder_removed-fold2.0_adjp0.05	CLEC18A CLEC18B CLEC18C WNT3A	3.93e-04	73	100	4	PCBC_ratio_ECTO_from-ESC_vs_ECTO_from-mRNA_cfr-2X-p05
CoexpressionAtlas	ECTO blastocyst_vs_ECTO UCB CD34+Z-Confounder_removed-fold2.0_adjp0.05	CLEC18A CLEC18B CLEC18C FBLN1 WNT3A LRP4 COBL	3.94e-04	284	100	7	PCBC_ratio_ECTO blastocyst_vs_ECTO UCB CD34+Z_cfr-2X-p05
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC ERBB4 THSD7A DNER PREX2 ADAMTS6 LRP4 FBN3	2.55e-08	200	105	8	7e51715525fdb001b7042b2bfcb9de81ecb5e4ee
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A DNER PREX2 ADAMTS6 FBN3	2.57e-07	182	105	7	420a8fd30543e37a66ba0786215d056d308660d0
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 HGFAC ERBB4 THSD7A DNER PREX2 ADAMTS6	2.87e-07	185	105	7	08fad1e3c3cc5f1c3eb6629a49c094b628e75a92
ToppCell	COPD-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	THSD7A HYAL1 GATA6 PREX2 MSRB3 ADAMTS9 NOTCH4	3.09e-07	187	105	7	be42ee71d3412bb1f52593d8814de85c354a0efa
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 THSD7A GATA6 ZFPM1 PREX2 ADGRE5 NOTCH4	3.20e-07	188	105	7	5bc1537e079c7435196c163bff5f639ea392a33a
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA6 ZFPM1 STAB1 MSRB3 MEGF6 ZFHX2 PLAGL1	3.44e-07	190	105	7	6f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 THSD7A GATA6 PREX2 MSRB3 MEGF6 NOTCH4	3.57e-07	191	105	7	b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A DNER PREX2 ADAMTS6 FBN3	3.69e-07	192	105	7	3abee376c37c3646da33ac381aa63d50a01607a6
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC3B THSD7A ADAMTSL3 FBLN1 TXNDC5 LOXL2 PCSK6	3.69e-07	192	105	7	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC3B THSD7A ADAMTSL3 FBLN1 TXNDC5 LOXL2 PCSK6	3.69e-07	192	105	7	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	COPD-Endothelial-VE_Arterial\|COPD / Disease state, Lineage and Cell class	THSD7A HYAL1 GATA6 PREX2 MSRB3 ADAMTS9 NOTCH4	3.83e-07	193	105	7	1c701b6ab5f0f0239634adac94fa1c92bf3c36f4
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PCSK5 THSD7A PREX2 MSRB3 ADAMTS6 ADAMTS9 NOTCH4	4.39e-07	197	105	7	ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ERBB4 THSD7A PREX2 ADAMTS6 LRP4 ADGRE5 FBN3	4.86e-07	200	105	7	501a3b93624df463458a35d3e6648d4ccc941724
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2-L1-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ERBB4 THSD7A PREX2 ADAMTS6 LRP4 ADGRE5 FBN3	4.86e-07	200	105	7	d1f36a8232411933b1494168ec912fd0e5246428
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC ERBB4 THSD7A DNER PREX2 ADAMTS6 FBN3	4.86e-07	200	105	7	75649534a98bc738fca62d071de0978dc61eb24f
ToppCell	Endothelial-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	THSD7A CARD10 NDP ADAMTSL3 MSRB3 ADAMTS9	2.84e-06	167	105	6	6a03d16165e0b003092c39972928981abd4a75aa
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 HGFAC SETX THSD7A HYAL1 CARD10	3.48e-06	173	105	6	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A CARD10 ADAMTS6 FBN3	3.72e-06	175	105	6	e78bf0c33a741bb97e987e41ac33da9e623a08ec
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 THSD7A DNER PREX2 ADAMTS6 FBN3	4.10e-06	178	105	6	3c973aac16988e88f5677d3d695dd772ccfd6570
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	THSD7A CARD10 PREX2 MSRB3 ADAMTS9 PCSK6	4.10e-06	178	105	6	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCSK5 THSD7A PREX2 ADAMTS6 ADAMTS9 NOTCH4	4.23e-06	179	105	6	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A DNER PREX2 ADAMTS6	4.23e-06	179	105	6	97ba67a856680f24846244c0b92c886cc0e79537
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCSK5 THSD7A PREX2 ADAMTS6 ADAMTS9 NOTCH4	4.23e-06	179	105	6	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SPEG TACC2 NDP GATA5 MSRB3 ADAMTS6	4.51e-06	181	105	6	25915e2500430a902db37d79a749ce2990b69810
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 THSD7A DNER PREX2 ADAMTS6 FBN3	4.51e-06	181	105	6	062f00736eed96e4f4327615d093558dd7d82b20
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A DNER PREX2 FBN3	4.51e-06	181	105	6	35bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A DNER PREX2 ADAMTS6	4.66e-06	182	105	6	7dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 THSD7A GATA6 TACC2 STAB1 ENAM	4.66e-06	182	105	6	ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 THSD7A GATA6 TACC2 STAB1 ENAM	4.66e-06	182	105	6	47ff6b4002a4167412c79210651316d1342503f9
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 ADAMTS10 SNED1 FBLN1 MEGF6 LRP4	4.81e-06	183	105	6	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A DNER PREX2 ADAMTS6	4.81e-06	183	105	6	e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 THSD7A DNER PREX2 ADAMTS6 ADAMTS9	4.81e-06	183	105	6	5e361be3ae3fe05098968e58427630127bd12675
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 THSD7A DNER PREX2 ADAMTS6 FBN3	4.96e-06	184	105	6	32473dbdb2de66391157c5814ef34e790806e4f2
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A DNER PREX2 ADAMTS6	5.12e-06	185	105	6	027020754dbf71b0034791f9a34ae795e3b85f81
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A DNER ADAMTS6 FBN3	5.12e-06	185	105	6	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A DNER PREX2 ADAMTS6	5.12e-06	185	105	6	bdfa8c284bbc5e85c806327fbb7778cf16242a38
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 THSD7A ADAMTS6 LRP4 ADGRE5 FBN3	5.12e-06	185	105	6	0b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCell	droplet-Thymus-nan-18m-Myeloid-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HCAR2 ZNF354A HYAL1 ZNF316 MEGF6 COBL	5.44e-06	187	105	6	ed69e7cbd6fb59363b0e26f24887fc49405397ce
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	PCSK5 THSD7A PREX2 ADAMTS6 ADAMTS9 NOTCH4	5.44e-06	187	105	6	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 THSD7A PREX2 MSRB3 MEGF6 NOTCH4	5.44e-06	187	105	6	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	THSD7A PREX2 MSRB3 ADAMTS6 ADAMTS9 NOTCH4	5.61e-06	188	105	6	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THSD7A ZNF618 STAB1 SNED1 LOXL2 PCSK6	5.96e-06	190	105	6	e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCell	Control-Epithelial-ATII\|Control / Disease state, Lineage and Cell class	ELAPOR2 ERBB4 GATA6 TACC2 PTPN13 COBL	5.96e-06	190	105	6	d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THSD7A ZNF618 STAB1 SNED1 LOXL2 PCSK6	5.96e-06	190	105	6	f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 THSD7A GATA6 PREX2 ADAMTS6 NOTCH4	5.96e-06	190	105	6	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THSD7A ZNF618 STAB1 SNED1 LOXL2 PCSK6	5.96e-06	190	105	6	b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel\|Adult / Lineage, Cell type, age group and donor	THSD7A CARD10 ADAMTSL3 MSRB3 ADAMTS9 PCSK6	5.96e-06	190	105	6	91bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 THSD7A GATA6 PREX2 MEGF6 NOTCH4	5.96e-06	190	105	6	d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 SPEG GATA5 SNED1 FBLN1 LRP4	6.14e-06	191	105	6	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 HGFAC ERBB4 DNER PREX2 TXNDC5	6.14e-06	191	105	6	7b386512284dfaa0e95358b28ee82632ee965e64
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 THSD7A GATA6 PREX2 ADAMTS6 NOTCH4	6.14e-06	191	105	6	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A ADAMTSL3 FBLN1 TXNDC5 LOXL2 PCSK6	6.33e-06	192	105	6	5e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 THSD7A GATA6 PREX2 MEGF6 NOTCH4	6.33e-06	192	105	6	285a9d332a1e07b94f222d4b518dd56928b9e075
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 THSD7A DNER PREX2 ADAMTS6 FBN3	6.33e-06	192	105	6	6a252e298f8a454623fa9c1c893a7a45a886d694
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A ADAMTSL3 FBLN1 TXNDC5 LOXL2 PCSK6	6.33e-06	192	105	6	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	Fibroblasts-CD55+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SPEG TACC2 NDP SNED1 PCSK6 ADAMTS16	6.52e-06	193	105	6	8f4bf9a2fbedae35432dad96730b00c70185874c
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA6 ADAMTSL3 ADAMTS10 FBLN1 TXNDC5 PCSK6	6.92e-06	195	105	6	690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCell	IPF-Endothelial-VE_Peribronchial\|IPF / Disease state, Lineage and Cell class	THSD7A PREX2 MSRB3 ADAMTS9 LOXL2 NOTCH4	6.92e-06	195	105	6	2c3ad3cb79f11119ac69c413a938d21199145040
ToppCell	mild-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF618 OXCT2 ADAMTS10 ENAM TXNDC5 NOTCH4	6.92e-06	195	105	6	1e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCell	facs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA6 ADAMTSL3 ADAMTS10 FBLN1 TXNDC5 PCSK6	6.92e-06	195	105	6	5c05e2bcea3d5d7ebe6325f7187ccf83301053d8
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THSD7A GATA6 CARD10 PREX2 MSRB3 NOTCH4	7.12e-06	196	105	6	915e4a7422058be246b54760df31e8a607310625
ToppCell	facs-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 FNDC3B FBLN1 TXNDC5 LOXL2 PCSK6	7.55e-06	198	105	6	0dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell	Tracheal-NucSeq-Endothelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THSD7A CARD10 PREX2 MSRB3 ADAMTS9 NOTCH4	7.55e-06	198	105	6	77e31b6edeeb5ccd5cd3f080898c96bf9ab9f98d
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	THSD7A CARD10 PREX2 MSRB3 ADAMTS9 LOXL2	7.77e-06	199	105	6	d359f3e1595ba8d8a3dc9eb2e8f2b61f3247c7a1
ToppCell	Skin-Endothelial\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	DPYSL2 THSD7A PREX2 ADAMTS9 LOXL2 NOTCH4	7.77e-06	199	105	6	6b3ef5d8f87cdfe5401d05f19339ddfcd9cda476
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	THSD7A HYAL1 PREX2 ADAMTS6 ADAMTS9 NOTCH4	7.77e-06	199	105	6	6a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCell	Neuronal-Inhibitory-iA\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC ERBB4 THSD7A DNER PREX2 ADAMTS6	7.99e-06	200	105	6	5ef4a3dc18a44292184a59ced916183c0699b01e
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC ERBB4 THSD7A DNER PREX2 FBN3	7.99e-06	200	105	6	913487e065dd580c9cbcbb3c3fc76a8d446f8856
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CCDC184-L1-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC ERBB4 THSD7A ADAMTS6 LRP4 FBN3	7.99e-06	200	105	6	140aff451cd58e1d544ee668e49e37e577f6f068
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CCDC184\|Neuronal / cells hierarchy compared to all cells using T-Statistic	HGFAC ERBB4 THSD7A ADAMTS6 LRP4 FBN3	7.99e-06	200	105	6	85bfa7f4dd07a4d4a88330e88f5886fd1ecfdeeb
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-1\|TCGA-Stomach / Sample_Type by Project: Shred V9	HRK CCDC187 SSPOP MEGF6 OTOF	9.30e-06	119	105	5	5d5fcddb5723e7a94bfcf56e165a980fa450b789
ToppCell	Mild/Remission-B_naive-13\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DUSP2 LINC00526 MSRB3 OTOF COBL	2.19e-05	142	105	5	49873a2d9b1ae4bdbf253d1c09bf8845cc0cc917
ToppCell	Mild/Remission-B_naive-13\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DUSP2 LINC00526 MSRB3 OTOF COBL	2.42e-05	145	105	5	7827aef87f834cd0d19780417757c9386e19b22e
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERBB4 DNER NDP GRXCR2 MEGF6	2.67e-05	148	105	5	5e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	WNT6 ADAMTSL3 FBLN1 GUCY2C IL17RE	3.13e-05	153	105	5	151c469b26f9adf04dd6f117f03bef760cc3d45d
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	THSD7A GATA6 GATA5 PREX2 NOTCH4	3.54e-05	157	105	5	275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCell	367C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PHF7 KIF20A LOXL2 PCSK6 ADAMTS16	3.99e-05	161	105	5	c61283c301a87bb802f6f8ce79c26067032dd7d9
ToppCell	367C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PHF7 KIF20A LOXL2 PCSK6 ADAMTS16	3.99e-05	161	105	5	9864d8b0929dacf4be7a4e97d2527ac3120ea264
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PCSK5 THSD7A PREX2 ADAMTS6 NOTCH4	4.11e-05	162	105	5	25bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERBB4 TMPRSS11E TACC2 IL17RE FBN3	4.11e-05	162	105	5	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	15-Airway-Mesenchymal-Airway_Smooth_Muscle\|Airway / Age, Tissue, Lineage and Cell class	THSD7A SPEG TACC2 GATA5 COBL	4.48e-05	165	105	5	531804467601e1ee1f771cffa21501f6d464ae10
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 THSD7A GATA6 PREX2 NOTCH4	4.61e-05	166	105	5	7a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 THSD7A GATA6 PREX2 NOTCH4	4.61e-05	166	105	5	bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D231\|Adult / Lineage, Cell type, age group and donor	THSD7A GATA6 PREX2 ADAMTS6 NOTCH4	4.88e-05	168	105	5	aca34c51758c65925ad24110294a72b2dea6db72
ToppCell	droplet-Heart-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL2 GATA6 ADAMTS10 FBLN1 PLAGL1	5.02e-05	169	105	5	2e5bb6437bc9c614e337c5ffb6f6457cd9fc7f4c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GATA5 PREX2 SNED1 IL17RE NOTCH4	5.02e-05	169	105	5	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-2_VIP_RPL41P3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A ADAMTS6 FBN3	5.17e-05	170	105	5	31e3f57673c99f4d8ef30faa9c40e5f7f5bf6460
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_ACHE\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A ADAMTS6 FBN3	5.17e-05	170	105	5	36dbbdb13f69307afd2122ff051b2980850c1f00
ToppCell	facs-Heart-RV-24m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP2 NDP ITGB7 WDR53 IL17RE	5.31e-05	171	105	5	dbffd55db0b3fc6eeb38d05189d84653f0111b31
ToppCell	facs-Heart-RV-24m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP2 NDP ITGB7 WDR53 IL17RE	5.31e-05	171	105	5	eee1199332c09aaae021134ee7c91661b11df50a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B ERBB4 DNER ADAMTS9 COBL	5.46e-05	172	105	5	0c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC187 NDP R3HDML FCGBP ADAMTS16	5.46e-05	172	105	5	c0bda7153e02bee7d0326138cc684151c404c2a1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FNDC3B ERBB4 DNER ADAMTS9 COBL	5.46e-05	172	105	5	eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	ZNF618 DUSP2 STAB1 SNED1 PCSK6	5.46e-05	172	105	5	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	THSD7A CARD10 MSRB3 ADAMTS9 PCSK6	5.61e-05	173	105	5	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal-GABAergic_neurons\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ERBB4 THSD7A COBL ST8SIA5	5.62e-05	88	105	4	5582fd7bac60c690ecd1f2aff1d446ccb69f79b9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGFAC ERBB4 THSD7A ADAMTS6 FBN3	5.77e-05	174	105	5	fdadac1eaab2c4a67e4832f0901df22e893add6a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PHF7 MSRB3 ADAMTS10 SNED1 SCAPER	6.09e-05	176	105	5	b4a23d8d1414434adeb237a96f28c825f1aebd77
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PHF7 MSRB3 ADAMTS10 SNED1 SCAPER	6.09e-05	176	105	5	66c9c6b59030f67e8d746a9c6930e50923f2ded1
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF618 FBLN1 PTPN13 ADAMTS16 COBL	6.26e-05	177	105	5	b7fee75de7e96924af488a5baa2334711889ae7c
Disease	hippocampal volume, brain volume measurement	HRK MSRB3	3.47e-05	3	101	2	EFO_0005035, EFO_0006930
Disease	Amyotrophic Lateral Sclerosis	ERBB4 SETX CAMK1G C9orf72	4.76e-05	58	101	4	C0002736
Disease	waist-hip ratio	PCSK5 FNDC3B HCAR2 ERBB4 ZNF407 IQCN ADAMTSL3 STAB1 MSRB3 ADAMTS10 MEGF8 ADAMTS6 ADAMTS9 ADAMTS20	7.45e-05	1226	101	14	EFO_0004343
Disease	Klatskin's tumor (is_implicated_in)	GATA6 PREX2	1.15e-04	5	101	2	DOID:4927 (is_implicated_in)
Disease	scoliosis (implicated_via_orthology)	SSPOP ADAMTS9	1.15e-04	5	101	2	DOID:0060249 (implicated_via_orthology)
Disease	erythronate measurement	PTPRA TKT	2.41e-04	7	101	2	EFO_0021025
Disease	inter-alpha-trypsin inhibitor heavy chain h4 measurement	STAB1 TKT	2.41e-04	7	101	2	EFO_0020481
Disease	FEV/FEC ratio	PCSK5 FNDC3B SPEG DNER GATA6 GATA5 ADAMTSL3 MSRB3 FBLN1 FCGBP MEGF6 SCAPER MYL10	2.87e-04	1228	101	13	EFO_0004713
Disease	Ventricular Septal Defects	PCSK5 IRX4	3.20e-04	8	101	2	C0018818
Disease	central serous retinopathy	GATA5 NOTCH4	3.20e-04	8	101	2	EFO_0009784
Disease	granule cell layer dentate gyrus volume	HRK MSRB3	3.20e-04	8	101	2	EFO_0009403
Disease	osteosarcoma	TASOR2 ADAMTS6	3.20e-04	8	101	2	EFO_0000637
Disease	hippocampal amigdala transition area volume	HRK MSRB3	6.25e-04	11	101	2	EFO_0009401
Disease	antihyperlipidemic drug use measurement	HGFAC WNT6 TMPRSS11E AMMECR1	6.68e-04	115	101	4	EFO_0803367
Disease	central corneal thickness	FNDC3B ZNF407 ADAMTS6 LOXL2 ADAMTS20 KLHL8	6.92e-04	309	101	6	EFO_0005213
Disease	smoking behavior, BMI-adjusted waist circumference	PCSK5 FNDC3B IQCN ADAMTSL3	8.34e-04	122	101	4	EFO_0004318, EFO_0007789
Disease	obesity (implicated_via_orthology)	ADAMTS9 GUCY2C ADAMTS20 ZFHX2 NOTCH4	8.81e-04	215	101	5	DOID:9970 (implicated_via_orthology)
Disease	tetralogy of Fallot (is_implicated_in)	GATA6 GATA5	8.83e-04	13	101	2	DOID:6419 (is_implicated_in)
Disease	corneal resistance factor	FNDC3B ZNF407 PTPN13 ADAMTS6 LOXL2 ADAMTS20 KLHL8	9.31e-04	451	101	7	EFO_0010067
Disease	ventricular septal defect (is_implicated_in)	GATA6 GATA5	1.03e-03	14	101	2	DOID:1657 (is_implicated_in)
Disease	Malignant neoplasm of skin	HCAR2 ERBB4 NOTCH4	1.10e-03	59	101	3	C0007114
Disease	Skin Neoplasms	HCAR2 ERBB4 NOTCH4	1.10e-03	59	101	3	C0037286
Disease	oral squamous cell carcinoma (is_marker_for)	ERBB4 KMT2D PTPN13	1.33e-03	63	101	3	DOID:0050866 (is_marker_for)
Disease	Tetralogy of Fallot	GATA6 GATA5	1.35e-03	16	101	2	C0039685
Disease	high altitude adaptation	HCAR2 LHX9	1.53e-03	17	101	2	EFO_0009105
Disease	Amyotrophic lateral sclerosis	SETX C9orf72	1.53e-03	17	101	2	cv:C0002736
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	HGFAC HCAR2 PCSK6 LRP4 KLHL8	2.17e-03	264	101	5	EFO_0008317, EFO_0020944
Disease	feeling "fed-up" measurement	ERBB4 DCAF5 LRP4	2.28e-03	76	101	3	EFO_0009588
Disease	amino acid measurement	ERBB4 SETX CLEC18C TACC2 WDR25 GUCY2C PCSK6 COBL	2.31e-03	678	101	8	EFO_0005134
Disease	ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)	GATA6 GATA5	2.56e-03	22	101	2	C1843687
Disease	hypothyroidism (biomarker_via_orthology)	DPYSL2 OTOF WNT3A	2.64e-03	80	101	3	DOID:1459 (biomarker_via_orthology)
Disease	Headache, type 2 diabetes mellitus	DCAF5 PCSK6	2.80e-03	23	101	2	HP_0002315, MONDO_0005148
Disease	lung squamous cell carcinoma (is_implicated_in)	KMT2D PTPN13	3.05e-03	24	101	2	DOID:3907 (is_implicated_in)
Disease	response to anticonvulsant	THSD7A PREX2 ADAMTS20	3.14e-03	85	101	3	GO_0036277
Disease	Schizophrenia	HCAR2 ERBB4 NDP ADAMTSL3 R3HDML PTPRA TXNDC5 C9orf72 NOTCH4	3.32e-03	883	101	9	C0036341

Protein segments in the cluster

Peptide	Gene	Start	Entry
GSARGHNGVRSCISC	PTRH1	136	Q86Y79
RTGAHSRGSVCSVCG	FAM246A	86	A0A494C0Y3
RTGAHSRGSVCSVCG	FAM246B	86	A0A494C0N9
TLVSTNGSSGCGRCH	ERBB4	176	Q15303
GGTCLKACASSHSLC	CARD10	456	Q9BWT7
GRLSCSSGGHDVCVS	CCDC187	116	A0A096LP49
RRSNCTNHCDLGDTS	AGAP9	221	Q5VTM2
FAAVSRGCCTSLTHL	CARMIL2	421	Q6F5E8
LGSKNGSTTCQCSHL	ADGRE5	516	P48960
LCTHGTCRNTVGSFH	FBN3	996	Q75N90
RTCGGGVSSSSRHCD	ADAMTS10	561	Q9H324
TCGGGVSHRSRLCTN	ADAMTS16	601	Q8TE57
CSSSCSGGLQHRAVV	ADAMTS20	1316	P59510
SRTCGGGVSSSLRHC	ADAMTS6	571	Q9UKP5
DGLIHNSGDCRSSTC	GUCY2C	86	P25092
ACSVCHSLSSRIGSP	IQCN	1041	Q9H0B3
NSLSTCCESGGRTLA	IRX4	21	P78413
SCSGSGDSGRRSHAC	FLG2	266	Q5D862
LGCSSAISAHCNFRL	RPGRIP1L	1106	Q68CZ1
RGSGSATCSLCHGSK	GRXCR2	201	A6NFK2
LSCGDLQVTGSAHCT	DPYSL2	321	Q16555
NGGANLCSSFSICHT	HCAR2	171	Q8TDS4
CSRCLCQHLLSGGSG	IL17RE	76	Q8NFR9
LHCTGNEATLAACTS	LOXL2	126	Q9Y4K0
HCQAGISRSATICLA	DUSP2	256	Q05923
HNCTECRDGLSLQGS	PCSK5	751	Q92824
GFTQLGTSCITNHTC	PCSK6	921	P29122
SVSHCRAGAGVAVCS	KLHL8	586	Q9P2G9
CSTCNKTLTTGDHFG	LHX9	161	Q9NQ69
LSGVCHSCGFISTTR	ZFPM1	346	Q8IX07
NSSLTGTLLHKDCCG	DCAF5	871	Q96JK2
CLTSATCHLRQGGAH	MEGF8	866	Q7Z7M0
ISAHCNLCLTGSSNS	MYL10	71	Q9BUA6
HCTAQLCASLALGSA	OR2I1P	96	Q8NGU4
RHTACLSSPCLNGGT	HGFAC	241	Q04756
ASSCRACALGSEQSG	ELAPOR2	601	A8MWY0
GRCSCSGQSSGHLCE	ITGB7	546	P26010
GSSHCRAGQTGVCLI	CAMK1G	461	Q96NX5
TARESHACLACSCNG	NTN3	301	O00634
ITGSHSCRLGESCIN	FBLN1	221	P23142
SRRAGLCCTNCHTTN	GATA5	236	Q9BWX5
SSRRLGLSCANCHTT	GATA6	436	Q92908
CGSSGTHLACSSLRS	G2E3	261	Q7L622
SSCSVSCGRGHKQRN	ADAMTS9	1451	Q9P2N4
TRTCQGSCAALSGLT	FCGBP	5131	Q9Y6R7
RACCISTGGHSQCSE	FNDC3B	646	Q53EP0
SALLAAIRGHSGTCS	COBL	1151	O75128
GESCLVHCLAGVSRS	DUSP22	81	Q9NRW4
SGSSHSKSCDQLRCG	RALGDS	681	Q12967
HVGSRGFGSNSCCSL	KRTAP13-3	96	Q3SY46
SGCHLRSAPCDLGAS	LINC00526	41	Q96FQ7
LLCSQALCSGHGRCV	HYAL1	356	Q12794
FHLSQRGSCCAGSST	ENAM	866	Q9NRM1
CRNGATCISSLSGFT	DNER	401	Q8NFT8
ELSCRNGGSHKSSCE	S100PBP	251	Q96BU1
ASSLLGHCSQVSCES	SCAPER	1251	Q9BY12
SHLQTCGCSVVVGSS	C9orf72	226	Q96LT7
SSNRLGCAIHTCSSI	R3HDML	176	Q9H3Y0
CRVLCNGGSSSHSTG	OTOF	1251	Q9HC10
THCSAGIGRSGTLIC	PTPN13	2406	Q12923
HCSAGAGRTGTFCAL	PTPRA	731	P18433
CACSAGRLGLRSSAA	HRK	16	O00198
HSADGRCKALSTCGA	OR4C3	226	Q8NH37
SAGHGSCDAISGLCL	MEGF6	876	O75095
ALHAASSGDLTCGVC	PLAGL1	111	Q9UM63
GSSQACRSCSSRHLP	SSPOP	151	A2VEC9
SSCSRSCGLGLTFQR	SSPOP	2511	A2VEC9
TLRTSCGNCSCAHGK	SSPOP	3786	A2VEC9
HGLSSLCNLGCVLSN	TMEM205	161	Q6UW68
CSKTCGSGLQHRTRH	THSD7A	206	Q9UPZ6
CGSHGTHRDCSSLRS	PHF7	276	Q9BWX1
LESHIICCTLSTSGG	SETX	2146	Q7Z333
HSRGILRVHTGTCSC	ST8SIA5	361	O15466
LCLAAALGSAQSGSC	MSRB3	21	Q8IXL7
DVSSLCHNGGLCVDS	NOTCH4	896	Q99466
GLALSQGCARCFATS	OXCT2	21	Q9BYC2
RVGGCGHTTSVCLAL	SNED1	261	Q8TER0
TCSCLSGFTGRRCHL	SNED1	296	Q8TER0
FGGCSHGSRCLRDST	SLURP2	31	P0DP57
SHCSGESQCRAGELG	AMMECR1	31	Q9Y4X0
SFVCTSCSGSLRGLN	AGFG1	46	P52594
SSHCGSRSCSAAAAR	LINC00612	161	Q8N6U2
ATSSQLGCGRHLCSA	CLEC18A	156	A5D8T8
ATSSQLGCGRHLCSA	CLEC18B	156	Q6UXF7
LGCGRHLCSAGQTAI	CLEC18B	161	Q6UXF7
ATSSQLGCGRHLCSA	CLEC18C	156	Q8NCF0
HCCGTRRSKTLGQSL	TMPRSS11E	176	Q9UL52
SRNIRSGVHSCAHGC	RNFT1	96	Q5M7Z0
LGSNACLGIGVTCHS	ZNF618	541	Q5T7W0
HQLLGCASGACSRGR	TAS1R1	401	Q7RTX1
TGGASGCRRCHATFS	ZFHX2	1666	Q9C0A1
SESNINLCGSHCGVS	TKT	406	P29401
ALTCTARNRHGTQTC	SPEG	1461	Q15772
QSAERACCHSTGAGK	KIF20A	756	O95235
ACCHSTGAGKLRQAL	KIF20A	761	O95235
SHTRTECKCHGLSGS	WNT6	216	Q9Y6F9
RGGCSEHANCLSTGL	STAB1	2141	Q9NY15
AACANTACSASGVGL	PREX2	1496	Q70Z35
SCGLLQTEHCLTSGE	TACC2	1156	O95359
HSISVASCGNIFSCG	WDR53	201	Q7Z5U6
LLARCEGHCSQASRS	NDP	61	Q00604
ACANCGRRFSQSSHL	ZNF316	916	A6NFI3
GTAAICGCSSRHQGS	WNT3A	131	P56704
TCNVSSHGIDGCDLL	WNT3A	296	P56704
HSGQGLILTACSVSC	SLC46A2	201	Q9BY10
RCLQCGAAFSHVSSL	ZNF835	391	Q9Y2P0
CTAHSDVCSAQGVRG	TXNDC5	121	Q8NBS9
GRQCSLNCISSGCHT	TASOR2	1216	Q5VWN6
LNCISSGCHTSGDSL	TASOR2	1221	Q5VWN6
SCSTSLSGCQRIHSR	ZNF354A	336	O60765
GNISRTCSHCGLLAS	ZNF407	846	Q9C0G0
TCSHCGLLASSITNL	ZNF407	851	Q9C0G0
SRACTLQGHTQACVG	WDR25	506	Q64LD2
LRALLGHCSNSAGST	ADAMTSL3	1056	P82987
SGISQRCSHCTRLGA	KMT2D	166	O14686
ACGRSHFTCAVSALG	LRP4	26	O75096