Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsyntaxin binding

CACNA1A GOLGA8N GOLGA8M GOLGA8O UNC13A

1.19e-04871105GO:0019905
GeneOntologyMolecularFunctionimportin-alpha family protein binding

GOLGA8N GOLGA8M GOLGA8O

2.01e-04211103GO:0061676
GeneOntologyCellularComponentGolgi cis cisterna

GOLGA8S GOLGA8R GOLGA8Q GOLGA8N GOLGA8M GOLGA8O

2.15e-08331136GO:0000137
GeneOntologyCellularComponentcis-Golgi network

GOLGA8S GOLGA8R BCL9 GOLGA8Q GOLGA8N GOLGA8M GOLGA8O

3.90e-07851137GO:0005801
GeneOntologyCellularComponentGolgi cisterna membrane

GOLGA8S GOLGA8R GOLGA8Q GOLGA8N GOLGA8M GOLGA8O GOLGA3

7.77e-07941137GO:0032580
GeneOntologyCellularComponentGolgi cisterna

GOLGA8S GOLGA8R GOLGA8Q GOLGA8N GOLGA8M GOLGA8O GOLGA3

8.76e-061351137GO:0031985
GeneOntologyCellularComponentGolgi stack

GOLGA8S GOLGA8R GOLGA8Q GOLGA8N GOLGA8M GOLGA8O GOLGA3

4.04e-051711137GO:0005795
GeneOntologyCellularComponentpostsynaptic endosome

VPS26B PIK3C3 SNX27

3.65e-04261133GO:0098845
GeneOntologyCellularComponentpostsynaptic early endosome

VPS26B SNX27

5.98e-0471132GO:0098842
GeneOntologyCellularComponentcentriolar satellite

KRT18 CCDC57 CCDC112 NEK1 TBC1D31

6.59e-041281135GO:0034451
DomainGOLGA2L5

GOLGA8R GOLGA8N GOLGA8M GOLGA8O

2.82e-06181064PF15070
DomainGolgin_A

GOLGA8R GOLGA8N GOLGA8M GOLGA8O

2.82e-06181064IPR024858
DomainCUT

CUX2 CUX1

6.58e-0471062PS51042
DomainCUT

CUX2 CUX1

6.58e-0471062PF02376
DomainCUT_dom

CUX2 CUX1

6.58e-0471062IPR003350
DomainCUT

CUX2 CUX1

6.58e-0471062SM01109
DomainSAM_2

CNKSR1 PPFIBP2 LRSAM1

1.86e-03431063PF07647
DomainHelicase_C

SMARCA5 DDX60 EIF4A2 RECQL5

3.23e-031071064PF00271
DomainHELICc

SMARCA5 DDX60 EIF4A2 RECQL5

3.23e-031071064SM00490
DomainHelicase_C

SMARCA5 DDX60 EIF4A2 RECQL5

3.34e-031081064IPR001650
DomainHELICASE_CTER

SMARCA5 DDX60 EIF4A2 RECQL5

3.45e-031091064PS51194
DomainHELICASE_ATP_BIND_1

SMARCA5 DDX60 EIF4A2 RECQL5

3.45e-031091064PS51192
DomainDEXDc

SMARCA5 DDX60 EIF4A2 RECQL5

3.45e-031091064SM00487
DomainHelicase_ATP-bd

SMARCA5 DDX60 EIF4A2 RECQL5

3.57e-031101064IPR014001
DomainPoly(ADP-ribose)pol_cat_dom

PARP11 PARP1

4.10e-03171062IPR012317
DomainPARP_CATALYTIC

PARP11 PARP1

4.10e-03171062PS51059
DomainPARP

PARP11 PARP1

4.10e-03171062PF00644
Domain-

PARP11 PARP1

4.10e-031710623.90.228.10
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SMARCA5 ERH KRT18 DSP DDX60 CAPNS1 PRPF8 THOC5 CEP170 DAP3 CRNKL1 PARP1 FARSA TRMT10C RBM25 CSE1L SMC3 LMO7 RTRAF EIF5B MOV10

6.56e-1012571132136526897
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

SMARCA5 URI1 NRDC KRT18 DSP CAPNS1 STARD7 PRPF8 TRIP10 RSRC1 CEP170 DAP3 CRNKL1 PARP1 FARSA TRMT10C CSE1L SMC3 RTRAF EIF5B

2.90e-0814151132028515276
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

DSP PRPF8 LARP7 CRNKL1 PARP1 RBM25 CSE1L SMC3 LMO7 EIF5B CUX1 MOV10

5.46e-084771131231300519
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

SMARCA5 ERH KRT18 DSP WDR46 PRPF8 FAM111B CRNKL1 KDM4D PARP1 RBM25 CSE1L SMC3 LMO7 EIF5B MOV10

7.80e-089491131636574265
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

SMARCA5 ERH DSP CAPNS1 PRPF8 THOC5 LARP7 RSRC1 CEP170 CRNKL1 PARP1 FARSA TRMT10C RBM25 CSE1L LMO7 RTRAF MOV10 MX2

9.17e-0813711131936244648
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

SMARCA5 ERH DSP PRPF8 THOC5 RSRC1 DAP3 CRNKL1 PARP1 FARSA RBM25 SMC3 RTRAF MOV10

1.17e-077311131429298432
Pubmed

GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.

BCL9 GOLGA8N GOLGA8M GOLGA8O

1.40e-0715113426165940
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

ERH KRT18 DDX60 LEMD2 PRPF8 LARP7 CEP170 ANKRD13A DAP3 PARP1 FARSA TRMT10C CSE1L LMO7 RTRAF PANK4 EIF5B CUX1 MOV10

1.95e-0714401131930833792
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

URI1 IFT172 RAB11FIP2 CAPNS1 PRPF8 RSRC1 CNOT6 CEP170 ANKRD13A NEK1 CHIC2 CSE1L SMC3 LMO7 EIF5B SNX27 MOV10 AGAP3

2.67e-0713211131827173435
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

ERH DSP PRPF8 LARP7 CEP170 DAP3 PARP1 FARSA TRMT10C RBM25 CSE1L SMC3 RTRAF EIF5B

3.97e-078091131432129710
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

SMARCA5 ERH KRT18 PPFIBP2 PRPF8 THOC5 LARP7 CRNKL1 PARP1 FARSA RBM25 CSE1L SMC3 LMO7 CNDP2 EIF5B CUX1

5.91e-0712471131727684187
Pubmed

Ror2 enhances polarity and directional migration of primordial germ cells.

GOLGA8N PARP1 GOLGA8M GOLGA8O

6.06e-0721113422216013
Pubmed

Dynamics of the rhomboid-like protein RHBDD2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosa.

BCL9 GOLGA8N GOLGA8M GOLGA8O

6.06e-0721113423386608
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

SMARCA5 PRPF8 CRNKL1 PARP1 RBM25 CSE1L SMC3 RTRAF

6.53e-07220113835785414
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

SMARCA5 ERH KRT18 PRPF8 TRIP10 LARP7 RSRC1 CRNKL1 RBM25 SMC3 LMO7 RTRAF CUX1 MOV10

6.85e-078471131435850772
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

SMARCA5 ERH KRT18 DSP PRPF8 LARP7 PARP1 RBM25 CSE1L SMC3 RTRAF CUX1

6.90e-076051131228977666
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CNKSR1 DSP IFT172 LRSAM1 CRTAC1 TRIM68 PRPF8 CUEDC1 CRNKL1 PARP1 LMO7 SCG3 RTRAF EIF4A2 GOLGA3 CUX1 AGAP3

8.93e-0712851131735914814
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

SMARCA5 KRT18 DSP WDR46 PRPF8 PLXNB2 CEP170 CRNKL1 PARP1 RBM25 CSE1L SMC3 LMO7 RTRAF EIF5B

1.20e-0610241131524711643
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

SMARCA5 WDR46 PRPF8 LARP7 RSRC1 DAP3 CRNKL1 PARP1 FARSA TRMT10C RBM25 SMC3 RTRAF EIF4A2 CNDP2 EIF5B MOV10

1.26e-0613181131730463901
Pubmed

CFP1 Regulates Histone H3K4 Trimethylation and Developmental Potential in Mouse Oocytes.

BCL9 GOLGA8N GOLGA8M GOLGA8O

1.27e-0625113428768200
Pubmed

CDK5RAP2 expression during murine and human brain development correlates with pathology in primary autosomal recessive microcephaly.

GOLGA8N GOLGA8M GOLGA8O CUX1

1.49e-0626113422806269
Pubmed

Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo.

GOLGA8N GOLGA8M GOLGA8O CUX1

1.49e-0626113431655624
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

SMARCA5 DSP PRPF8 PARP1 RBM25 SMC3 LMO7 RTRAF MOV10

1.80e-06340113924332808
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

VPS26B PRPF8 PARP1 CSE1L GRK2 CNDP2 EIF5B SNX27 MOV10

1.98e-06344113930333137
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

KRT18 DSP PRPF8 CEP170 LMO7 EIF5B SNX27 GOLGA8O

2.03e-06256113833397691
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

ERH WDR46 PRPF8 LARP7 DAP3 CRNKL1 PARP1 FARSA TRMT10C RBM25 EIF4A2 EIF5B MOV10

2.34e-068071131322681889
Pubmed

Ttyh1, a Ca(2+)-binding protein localized to the endoplasmic reticulum, is required for early embryonic development.

LARP7 GOLGA8N GOLGA8M GOLGA8O

2.36e-0629113420568244
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SMARCA5 DSP PRPF8 THOC5 CEP170 DAP3 CRNKL1 PARP1 FARSA TRMT10C RBM25 CSE1L SCG3 EIF5B UNC13A

2.37e-0610821131538697112
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RGPD4 CACNA1A ERH BCL9 GOLGA8N CEP170 PARP1 FARSA GOLGA8M EIF4A2 GOLGA8O UNC13A GOLGA3 CUX1

3.06e-069631131428671696
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

ERH KRT18 PRPF8 THOC5 LARP7 RSRC1 CEP170 DAP3 TRMT10C RBM25 EIF5B MOV10

3.76e-067131131229802200
Pubmed

IRX3/5 regulate mitotic chromatid segregation and limb bud shape.

CUX2 SMC3 CUX1

3.94e-0610113332907847
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RGPD4 SMARCA5 CUX2 KRT18 DSP PRPF8 CCDC57 LARP7 IVD DAP3 PARP1 TBC1D31 LMO7 SCG3 EIF4A2 EIF5B CUX1

4.21e-0614421131735575683
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

SMARCA5 ERH PRPF8 PARP1 SMC3 RTRAF

4.23e-06129113623022380
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

PRPF8 CEP170 DAP3 PARP1 FARSA RBM25 SMC3 RTRAF EIF5B MOV10

4.45e-064861131030940648
Pubmed

Palmitoylation regulates epidermal homeostasis and hair follicle differentiation.

GOLGA8N GOLGA8M TCHH GOLGA8O

4.54e-0634113419956733
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

NRDC KRT18 DSP STARD7 PRPF8 PLXNB2 CNOT6 CEP170 EDEM3 PARP1 TRMT10C SMC3 PIK3C3 RTRAF EIF4A2 EIF5B

4.71e-0612971131633545068
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

PRPF8 CEP170 DAP3 PARP1 FARSA TRMT10C RBM25 CSE1L RTRAF

4.73e-06383113929331416
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

NRDC PPFIBP2 HJURP LEMD2 WDR46 PRPF8 LARP7 CEP170 DAP3 FARSA EIF5B CUX1

4.91e-067321131234732716
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

SMARCA5 ERH KRT18 DSP PRPF8 LARP7 DAP3 PARP1 FARSA TRMT10C CSE1L SMC3 RTRAF EIF4A2 MOV10

5.10e-0611531131529845934
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

URI1 CAPNS1 PRPF8 LARP7 PARP1 RTRAF EIF4A2 GOLGA3 MOV10

5.47e-06390113917643375
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

URI1 ERH CAPNS1 PRPF8 LARP7 DAP3 PARP1 RTRAF RECQL5 EIF5B MOV10

5.52e-066151131131048545
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

SMARCA5 ERH PRPF8 THOC5 LARP7 CCNC CRNKL1 PARP1 FARSA RBM25 CSE1L SMC3 CNDP2 EIF5B

5.53e-0610141131432416067
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

RGPD4 ERH KRT18 DSP LEMD2 PRPF8 CEP170 PARP1 LMO7 RTRAF CUX1

6.52e-066261131133644029
Pubmed

Characterization of the piRNA complex from rat testes.

GBA2 GOLGA8N GOLGA8M ARHGAP20 GOLGA8O CUX1

6.78e-06140113616778019
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SMARCA5 ERH KRT18 DSP LRSAM1 WDR46 PRPF8 CRNKL1 PARP1 ALKBH1 CSE1L SMC3 RECQL5 EIF5B SNX27 MOV10

8.00e-0613531131629467282
Pubmed

Nuclear Functions of Nucleolin through Global Proteomics and Interactomic Approaches.

SMARCA5 ERH PRPF8 CEP170 DAP3 SMC3

8.29e-06145113627049334
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

RGPD4 ERH KRT18 DSP ANKRD13A DAP3 LMO7 RTRAF SNX27 MOV10 MX2

8.88e-066471131126618866
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

SMARCA5 ERH KRT18 DSP PRPF8 PLXNB2 TRIP10 IVD CEP170 ANKRD13A DAP3 PARP1 TRMT10C ANO6 EIF4A2 EIF5B

9.10e-0613671131632687490
Pubmed

Globozoospermia and lack of acrosome formation in GM130-deficient mice.

GOLGA8N GOLGA8M GOLGA8O

9.33e-0613113328055014
Pubmed

GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells.

GOLGA8N GOLGA8M GOLGA8O

9.33e-0613113333740186
Pubmed

Loss of GM130 does not impair oocyte meiosis and embryo development in mice.

GOLGA8N GOLGA8M GOLGA8O

9.33e-0613113332873390
Pubmed

GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte.

GOLGA8N GOLGA8M GOLGA8O

9.33e-0613113321552007
Pubmed

GOLGA2 loss causes fibrosis with autophagy in the mouse lung and liver.

GOLGA8N GOLGA8M GOLGA8O

9.33e-0613113329128360
Pubmed

Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice.

GOLGA8N GOLGA8M GOLGA8O

9.33e-0613113328028212
Pubmed

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

KRT18 THOC5 CCNC CRNKL1 RBM25 EIF4A2 AGAP3

9.33e-06225113725277244
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

RGPD4 SMARCA5 ERH KRT18 DSP PRPF8 THOC5 PARP1 SMC3 LMO7 RECQL5

9.54e-066521131131180492
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

SMARCA5 DSP WDR46 PRPF8 LARP7 CEP170 CRNKL1 RBM25 CSE1L EIF5B MOV10

9.68e-066531131122586326
Pubmed

Cux1 and Cux2 selectively target basal and apical dendritic compartments of layer II-III cortical neurons.

CUX2 CUX1

1.05e-052113225059644
Pubmed

Cux-1 and Cux-2 control the development of Reelin expressing cortical interneurons.

CUX2 CUX1

1.05e-052113218327765
Pubmed

A unique variant of a homeobox gene related to Drosophila cut is expressed in mouse testis.

CUX2 CUX1

1.05e-05211328879483
Pubmed

Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors. Distinct molecular events with different GRK2 requirements.

HTR4 GRK2

1.05e-052113215919661
Pubmed

CUX2 deficiency causes facilitation of excitatory synaptic transmission onto hippocampus and increased seizure susceptibility to kainate.

CUX2 CUX1

1.05e-052113235581205
Pubmed

Expression of a cut-related homeobox gene in developing and polycystic mouse kidney.

CUX2 CUX1

1.05e-05211328840273
Pubmed

Spermatid head elongation with normal nuclear shaping requires ADP-ribosyltransferase PARP11 (ARTD11) in mice.

PARP11 PARP1

1.05e-052113225673562
Pubmed

Cux1 Enables Interhemispheric Connections of Layer II/III Neurons by Regulating Kv1-Dependent Firing.

CUX2 CUX1

1.05e-052113226804994
Pubmed

Differential expression and biodistribution of cytokeratin 18 and desmoplakins in non-small cell lung carcinoma subtypes.

KRT18 DSP

1.05e-052113211955647
Pubmed

Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors.

GOLGA8N GOLGA8M GOLGA8O CUX1

1.07e-0542113424210661
Pubmed

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.

GOLGA8N GOLGA8M TRMT10C EIF4A2 PLEKHA1 GOLGA8O AGAP3

1.08e-05230113735449600
Pubmed

GM130 and p115 play a key role in the organisation of the early secretory pathway during skeletal muscle differentiation.

GOLGA8N GOLGA8M GOLGA8O

1.18e-0514113330630895
Pubmed

Cdk1 protects against oxygen-glucose deprivation and reperfusion-induced Golgi fragmentation and apoptosis through mediating GM130 phosphorylation.

GOLGA8N GOLGA8M GOLGA8O

1.18e-0514113337831422
Pubmed

Golgb1 regulates protein glycosylation and is crucial for mammalian palate development.

GOLGA8N GOLGA8M GOLGA8O

1.18e-0514113327226319
Pubmed

Oligoasthenoteratospermia and sperm tail bending in PPP4C-deficient mice.

GOLGA8N GOLGA8M GOLGA8O

1.18e-0514113333543287
Pubmed

Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.

DSP PRPF8 PARP1 TRMT10C RBM25 CSE1L EIF5B

1.27e-05236113736339263
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SMARCA5 ERH KRT18 DSP PRPF8 CEP170 CRNKL1 PARP1 RBM25 RTRAF RECQL5 EIF5B CUX1

1.41e-059541131336373674
Pubmed

Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum.

GOLGA8N GOLGA8M GOLGA8O

1.48e-0515113317204322
Pubmed

Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain.

GOLGA8N GOLGA8M GOLGA8O

1.48e-0515113316413118
Pubmed

Golgi disruption and early embryonic lethality in mice lacking USO1.

GOLGA8N GOLGA8M GOLGA8O

1.48e-0515113323185636
Pubmed

The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cells.

GOLGA8N GOLGA8M GOLGA8O

1.48e-0515113317046993
Pubmed

Mouse oocytes within germ cell cysts and primordial follicles contain a Balbiani body.

GOLGA8N GOLGA8M GOLGA8O

1.48e-0515113317189423
Pubmed

RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis.

GOLGA8N GOLGA8M GOLGA8O

1.48e-0515113326083584
Pubmed

WDR38, a novel equatorial segment protein, interacts with the GTPase protein RAB19 and Golgi protein GM130 to play roles in acrosome biogenesis.

GOLGA8N GOLGA8M GOLGA8O

1.48e-0515113337635409
Pubmed

Golga5 is dispensable for mouse embryonic development and postnatal survival.

GOLGA8N GOLGA8M GOLGA8O

1.48e-0515113328509431
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

SMARCA5 NRDC DSP WDR46 PRPF8 LARP7 DAP3 CRNKL1 PARP1 FARSA TRMT10C RBM25 CSE1L SMC3 RTRAF EIF5B

1.52e-0514251131630948266
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

SMARCA5 NRDC PRPF8 THOC5 CEP170 DAP3 TRMT10C CSE1L SMC3 PANK4

1.52e-055601131035241646
Pubmed

LIM kinase 2 is widely expressed in all tissues.

GOLGA8N GOLGA8M GOLGA8O

1.81e-0516113316399995
Pubmed

Molecular motor KIF1C is not essential for mouse survival and motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport.

GOLGA8N GOLGA8M GOLGA8O

1.81e-0516113311784862
Pubmed

p125/Sec23-interacting protein (Sec23ip) is required for spermiogenesis.

GOLGA8N GOLGA8M GOLGA8O

1.81e-0516113321640725
Pubmed

Molecular characterization of mitocalcin, a novel mitochondrial Ca2+-binding protein with EF-hand and coiled-coil domains.

GOLGA8N GOLGA8M GOLGA8O

1.81e-0516113316336229
Pubmed

SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis.

GOLGA8N GOLGA8M GOLGA8O

1.81e-0516113318166528
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

SMARCA5 VPS26B WDR46 PRPF8 TRIP10 DAP3 FARSA SMC3 EIF4A2 SNX27 MOV10

1.94e-057041131129955894
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SMARCA5 DSP SFI1 PRPF8 PARP1 CSE1L SMC3 LMO7 EIF4A2 STK24

2.12e-055821131020467437
Pubmed

Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis.

GOLGA8N GOLGA8M GOLGA8O

2.20e-0517113314718562
Pubmed

Dynamics and function of CXCR4 in formation of the granule cell layer during hippocampal development.

GOLGA8N GOLGA8M GOLGA8O

2.20e-0517113328717168
Pubmed

The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.

GOLGA8N GOLGA8M GOLGA8O

2.20e-0517113327655914
Pubmed

Vesicle budding from endoplasmic reticulum is involved in calsequestrin routing to sarcoplasmic reticulum of skeletal muscles.

GOLGA8N GOLGA8M GOLGA8O

2.20e-0517113314728599
Pubmed

A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly.

GOLGA8N GOLGA8M GOLGA8O

2.20e-0517113320004763
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

SMARCA5 ERH PRPF8 DAP3 CRNKL1 PARP1 FARSA CSE1L SMC3 RTRAF MOV10

2.21e-057141131128302793
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

KRT18 DSP PRPF8 CEP170 DAP3 PARP1 CSE1L SMC3 LMO7 RTRAF EIF4A2 PANK4 EIF5B MOV10

2.23e-0511491131435446349
Pubmed

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

ERH DSP DDX60 LARP7 FAM111B DAP3 SMC3 RTRAF MOV10

2.36e-05469113937314180
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

RGPD4 ERH HJURP PRPF8 LARP7 RSRC1 CNOT6 CEP170 EDEM3 CRNKL1 SMC3 EIF4A2 MOV10 TTC33

2.36e-0511551131420360068
InteractionSF3A1 interactions

ERH PRPF8 TRIP10 THOC5 LARP7 CRNKL1 KDM4D PARP1 RBM25 ARHGAP20 MOV10 TTC33

1.23e-0547111212int:SF3A1
InteractionCIT interactions

SMARCA5 ERH DSP DDX60 HEATR5A PRPF8 ZZEF1 THOC5 CEP170 CRNKL1 TRMT10C RBM25 CSE1L SMC3 LMO7 RTRAF EIF4A2 PANK4 EIF5B SNX27 OSGIN2 CUX1

1.35e-05145011222int:CIT
InteractionCASP7 interactions

KRT18 DSP PARP1 CNDP2 STK24 GOLGA3

1.69e-05971126int:CASP7
InteractionAR interactions

SMARCA5 KRT18 DSP TRIM68 BCL9 PRPF8 DAP3 CRNKL1 KDM4D PARP1 FARSA RBM25 CSE1L SMC3 RTRAF CNDP2 CUX1

3.32e-0599211217int:AR
InteractionNCL interactions

SMARCA5 ERH DSP RAB11FIP2 WDR46 PRPF8 LARP7 CEP170 DAP3 PARP1 SMC3 RECQL5 EIF5B CCDC65 FGFBP1

3.55e-0579811215int:NCL
CytobandEnsembl 112 genes in cytogenetic band chr15q13

GOLGA8R GOLGA8Q GOLGA8N GOLGA8M GOLGA8O

5.16e-061001135chr15q13
GeneFamilyCUT class homeoboxes and pseudogenes

CUX2 CUX1

6.00e-049752527
CoexpressionMITSIADES_RESPONSE_TO_APLIDIN_DN

URI1 DSP HJURP PRPF8 RSRC1 EDEM3 PARP1 CSE1L SMC3

1.43e-062501139M11318
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CUX2 KRT18 DSP CCDC141 ENPEP FGFBP1

6.27e-06178113676e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CUX2 KRT18 DSP CCDC141 ENPEP FGFBP1

6.27e-06178113682f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCelldroplet-Lung-30m-Epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CUX2 KRT18 DSP CCDC141 ENPEP FGFBP1

6.27e-0617811365442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CUX2 KRT18 DSP CCDC141 ENPEP FGFBP1

6.27e-061781136523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCellE18.5-samps|World / Age Group, Lineage, Cell class and subclass

KRT18 CCDC141 LMO7 EIF4A2 CUX1 FGFBP1

7.12e-0618211369649f15858d1ede73e068afc59df3ac367b49687
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CAPNS1 HJURP CRTAC1 KCNIP1 FAM111B PLD5

9.66e-061921136b18ae7337eaad1315a5b0ee81c75f7606bd3c7fe
ToppCell368C-Myeloid-Dendritic-cDC2|368C / Donor, Lineage, Cell class and subclass (all cells)

GOLGA8R GOLGA8N CCDC112 GOLGA8M TCHH ALOX5

1.02e-051941136eb9656d6d2da9aa074e6f5c06d750a6f9828208a
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

CACNA1A PARP11 DSP DDX60 MOV10 MX2

1.06e-051951136b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_activated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A TFEC EDEM3 TCHH RECQL5 ZNF589

1.18e-0519911363b2bd3caf4d189a1726a737b0121860b265eec04
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

AADAC LARP7 RBM25 SMC3 LMO7 EIF5B

1.18e-051991136a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

KRT18 DSP HEATR5A PLXNB2 LMO7 PLD5

1.22e-0520011362dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellLPS_only-Epithelial_alveolar-AT_1|LPS_only / Treatment groups by lineage, cell group, cell type

KRT18 DSP HEATR5A PLXNB2 LMO7 PLD5

1.22e-0520011369a6ae40f3e17cd44ee5fd73260713b920aa2ea15
ToppCellCOVID-19-kidney-Mito-rich_Int|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A CUX2 FAT3 PLD5 FGFBP1

1.96e-05129113557b705106aec7bbfc587de1ccd4f2335fc44dd6f
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GOLGA8Q FMNL3 TCHH SCG3 MMP12

4.73e-051551135d76a0f99ec35560d18820f9c92b69364ef2250e3
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT1|PND01-03-samps / Age Group, Lineage, Cell class and subclass

KRT18 DSP LMO7 CUX1 FGFBP1

6.37e-051651135b9b6b7b8cd65ba6948a5dd8b715cc7092e0be637
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A SLC26A7 SCG3 RPE65 UNC13A

6.55e-051661135d96c562e1483adb4cdd817b68133f03356d7279b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TFEC HJURP CCDC141 FAM111B SCG3

7.75e-051721135ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SMARCA5 KRT18 DSP LMO7 AGAP3

8.18e-0517411352cd6638b361ca05ab83d09ce657194aed97873b7
ToppCellfacs-Trachea-nan-18m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT18 DSP TCHH LMO7 FGFBP1

8.40e-0517511353883675a726dd0c6c3a7113d59be2a093ea2dc6f
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT18 FAT3 CUEDC1 EDEM3 ALOX5

9.60e-05180113541e8155cc7b3dac9d496e4077845ca6af1591a5c
ToppCelldroplet-Lung-LUNG-30m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CUX2 KRT18 DSP CCDC141 FGFBP1

9.85e-051811135cadb18fc73031eb9f779599e15cd7861337fee78
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A DSP SLC26A7 SCG3 UNC13A

9.85e-051811135cb17c904ab86d56dd30cac9b61acbb3b76f84ded
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CUX2 KRT18 DSP CCDC141 FGFBP1

9.85e-05181113585bec4d3f255f4c61c790325eeb50ad38f709ef2
ToppCellCOVID-19_Mild-CD4+_T_activated|COVID-19_Mild / Disease condition and Cell class

NRDC DDX60 GRK2 RTRAF MX2

1.01e-041821135877b6e611626628e709568747512f2827ebb2795
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CACNA1A PARP11 DSP DDX60 MX2

1.04e-041831135dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

NRDC ADA2 GOLGA8Q GRK2 GOLGA8O

1.04e-04183113522bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCellControl-Epithelial-ATII|World / Disease state, Lineage and Cell class

AADAC KRT18 CRTAC1 CCDC141 LMO7

1.12e-041861135f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

KRT18 CRTAC1 CCDC141 LMO7 FGFBP1

1.21e-0418911356f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

KRT18 CRTAC1 CCDC141 LMO7 FGFBP1

1.21e-041891135926b5fa3064b501a57ba78583e8af33532add455
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AADAC SMARCA5 STARD7 SMC3 ARHGAP20

1.24e-04190113536e83995021ba16690f84e2077a9e8baec547d05
ToppCellControl-Epithelial-ATII|Control / Disease state, Lineage and Cell class

AADAC KRT18 CRTAC1 CCDC141 LMO7

1.24e-041901135d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCelldroplet-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT18 DSP CCDC141 ENPEP FGFBP1

1.24e-041901135a51405f8466fc6d4087873137472619b2e84c1da
ToppCelltumor_Lung-Fibroblasts-Mesothelial_cells|Fibroblasts / Location, Cell class and cell subclass

AADAC KRT18 DSP BRINP2 FGFBP1

1.24e-041901135d82ab67735c1f365d4b0e02b5fa91c64cdc234da
ToppCell368C-Epithelial_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

KRT18 CRTAC1 CCDC141 LMO7 FGFBP1

1.24e-041901135459811e88d3001816c2d89034e0921c24918c17f
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AADAC SMARCA5 STARD7 SMC3 ARHGAP20

1.24e-041901135d26be9e1b676f750e716b91ebc3598fac3735612
ToppCelldroplet-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT18 DSP CCDC141 ENPEP FGFBP1

1.24e-041901135059beca1c92181b8ba4dcd6fc71ff7530d83d0de
ToppCelldroplet-Lung-18m-Epithelial-alveolar_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT18 DSP CCDC141 ENPEP FGFBP1

1.27e-041911135caed913e7ede9f8ae3af273d1ecf375de6c5e813
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KRT18 PPFIBP2 LMO7 CUX1 FGFBP1

1.33e-04193113554506c0da2f219f472b95e8935a78b657a8dec41
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT18 DSP CCDC141 SLC26A7 LMO7

1.33e-041931135c5925b3b5d19098e3987789d68a493d7fd548ac9
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KRT18 PPFIBP2 LMO7 CUX1 FGFBP1

1.33e-0419311352d42721fac1bee294ede47d609bebb3e7d36bf0c
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT18 DSP CCDC141 SLC26A7 LMO7

1.33e-0419311356905de261d90dfe3dd2c2cf5b2e26afb2bcc3d5b
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KRT18 DSP CCDC141 SLC26A7 LMO7

1.33e-041931135f73630725f093c646bdaf178c39505c04a16e2c6
ToppCellfacs-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT18 DSP CCDC141 SLC26A7 LMO7

1.36e-0419411353701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCellfacs-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT18 DSP CCDC141 SLC26A7 LMO7

1.36e-04194113565f9bf126be26114c2c3f4c46d48318986212a92
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KRT18 PLXNB2 ANKRD13A STK24 ALOX5

1.36e-0419411354579b4a44f7c731553a284843c296866027d7c0e
ToppCell368C-Myeloid-Dendritic|368C / Donor, Lineage, Cell class and subclass (all cells)

GOLGA8R CCDC112 GOLGA8M TCHH ALOX5

1.36e-0419411354f88759d92ac229b1edd2d4b69b878bbf2d9b6bd
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

KRT18 DSP CRTAC1 KCNIP1 CCDC141

1.40e-041951135de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CNKSR1 KRT18 DSP CCDC65 FGFBP1

1.40e-041951135ed052c6d3dc104b02e34b645abfdee477af050c6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TFEC CCDC141 ADA2 ALOX5 MX2

1.40e-041951135ce8215d503cad3a9bc7d5d2be4adb57408015593
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TFEC CCDC141 ADA2 ALOX5 MX2

1.40e-04195113509df40ff9b493170861b3f6e57a942a834655b5c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KRT18 PLXNB2 ANKRD13A STK24 ALOX5

1.40e-0419511353d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KRT18 DSP LMO7 CUX1 FGFBP1

1.43e-0419611359790340c25f446ec655f5a0b64ec3bb44ed2e1bd
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KRT18 DSP LMO7 CUX1 FGFBP1

1.43e-041961135b9ceceeacbcf81976ce92adf044f0d0aa132632b
ToppCellwk_15-18-Epithelial-Distal_epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CNKSR1 SMARCA5 KRT18 DSP LMO7

1.46e-041971135b7aff83c27606d87565382a768119a863fe1c294
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KRT18 DSP LMO7 CUX1 FGFBP1

1.46e-041971135b0fb5774525ba05f60c635d42f14bb8d79bff17c
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KRT18 DSP CCDC141 PLXNB2 LMO7

1.46e-0419711353d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TFEC HJURP FAM111B BRINP2 ALOX5

1.46e-041971135d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCellControl_saline-Epithelial_alveolar-AT_2|Control_saline / Treatment groups by lineage, cell group, cell type

AADAC KRT18 DSP CCDC141 LMO7

1.46e-041971135b8f62fcd6eb8f47b3cc41f616126f82c68a36e87
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KRT18 DSP LMO7 CUX1 FGFBP1

1.46e-041971135bbb7c106d5b96b8e95aeb3e5c293e104fceea234
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AADAC TFEC KRT18 DSP LMO7

1.46e-041971135f097e729f515e7945b9482e9f9dbc9536b90f0bb
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KRT18 DSP HEATR5A LMO7 PLD5

1.50e-0419811351282db321e27499d310339d6383974614e295a20
ToppCelldistal-Epithelial-Club-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AADAC KRT18 DSP CRTAC1 LMO7

1.50e-041981135e56a5ffadfa4d1e34d34aec43eaf560cd80286e1
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

KRT18 DSP HEATR5A LMO7 MX2

1.50e-04198113585f424cd9bb3117c9e322031024aabb87696ce47
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KRT18 DSP HEATR5A LMO7 PLD5

1.50e-041981135b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCellAT2_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

AADAC KRT18 CRTAC1 CCDC141 LMO7

1.50e-0419811358a1f984e46f4fa5be33027b9dbaa2ca060a2245d
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GOLGA8S TFEC CNDP2 ALOX5 MX2

1.50e-0419811359a77038e5db0ea757fd7ebcab294785b166ddc12
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CNKSR1 SMARCA5 KRT18 DSP LMO7

1.50e-041981135c477405b093f4e5374e57bcacf1fb204a0f7eb3b
ToppCellControl_saline-Epithelial_alveolar-AT_1|Control_saline / Treatment groups by lineage, cell group, cell type

KRT18 DSP HEATR5A LMO7 MX2

1.50e-0419811359b161285df7a4e51618f3517cfc5b8221ba55786
ToppCelldistal-1-Epithelial-Club|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AADAC KRT18 DSP CRTAC1 LMO7

1.53e-0419911358f0a72a95d0310ef2324c6975495c294b5a47cc8
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT18 DSP PLXNB2 TRIP10 LMO7

1.53e-0419911355a1557fe35aa48080d4967e8724bf27f9585a5fb
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT18 DSP PLXNB2 TRIP10 LMO7

1.53e-0419911350a657475b92aa3a713da62da364525249fdc3886
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

AADAC LARP7 SMC3 RTRAF EIF5B

1.53e-04199113519674e1eaeb51e4196d847cb62aa437c852951d3
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KRT18 DSP HEATR5A LMO7 PLD5

1.53e-041991135d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT18 DSP PLXNB2 TRIP10 LMO7

1.53e-041991135a8f4bd0e65f36b29535864fae4347369d5c864d2
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT18 DSP PLXNB2 TRIP10 LMO7

1.53e-041991135667e1a56c33a2681af8dc1b7dbc3a9858e2c3c05
ToppCell10x5'v1-week_14-16-Myeloid_monocytic-monocyte-promonocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TFEC CAPNS1 PLXNB2 ADA2 GRK2

1.53e-041991135f7661a386224682e1d79cc9949204d05c0dfe324
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT18 DSP PLXNB2 TRIP10 LMO7

1.53e-041991135245b37df56dfbbdbac88f0e2fc3dfa0ed1abd588
ToppCell10x5'v1-week_14-16-Myeloid_monocytic|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TFEC CAPNS1 PLXNB2 ADA2 GRK2

1.53e-0419911355caaf66b6cddcc8f0d0aee3c9ba80d02075e87e5
ToppCell10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-pre_B_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ERH FAM111B CCDC112 PARP1 SMC3

1.53e-041991135dadee9fc6ce4f4bdb19d29326889316443dda0cb
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT18 DSP PLXNB2 TRIP10 LMO7

1.53e-0419911352dae9db4d25f1a390134da2b6621564b274fe910
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KRT18 DSP HEATR5A LMO7 PLD5

1.53e-041991135a270630626df614f8605abddb7dee7c4d74f6149
ToppCell10x5'v1-week_14-16-Myeloid_monocytic-monocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TFEC CAPNS1 PLXNB2 ADA2 GRK2

1.53e-0419911357f5d47e49776114d9f4a42017fead9eeb415a94c
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT18 DSP PLXNB2 TRIP10 LMO7

1.53e-041991135eacea42e973f073b410f54c0a1b3a7f2dc2b5a29
ToppCelldistal-Epithelial-Club|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AADAC KRT18 DSP CRTAC1 LMO7

1.53e-041991135c63ccce1285352927fd8c4f7374ec5fff8d70cec
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT18 DSP PLXNB2 TRIP10 LMO7

1.53e-041991135dbb33f0e151b150ba9ca4612973f8034c62e762b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_|World / Primary Cells by Cluster

FAT3 CEP170 LMO7 SCG3 EIF4A2

1.53e-041991135058373b4ac3cec2108cb24265628ff0a50646e33
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT18 DSP PLXNB2 LMO7 FGFBP1

1.57e-042001135f386a86b127433cbac306950443355bd723080ff
ToppCelldistal-Epithelial|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AADAC KRT18 DSP CRTAC1 LMO7

1.57e-0420011350a97080f694738bb882787cee21b91a4d5757b7a
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

DSP SLC13A3 TRIM68 CCDC141 LMO7

1.57e-042001135eac33be484dc443794e66e473f03e98406c2983e
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KRT18 DSP HEATR5A LMO7 PLD5

1.57e-0420011358683445ad5b70748c4a1f12eb77d47623085147e
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

FAT3 CEP170 LMO7 EIF4A2 ARHGAP20

1.57e-042001135db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT18 DSP PLXNB2 LMO7 FGFBP1

1.57e-042001135b75154417c215b8853186bff46d624ebd387ac4f
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

FAT3 CEP170 LMO7 EIF4A2 ARHGAP20

1.57e-04200113530a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Cortical_neuron|GW26 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1A CUX2 CEP170 CCDC112 AGAP3

1.57e-0420011355b3df61ff421846ef4cabf1bd5355534c8b95509
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TFEC PPFIBP2 TBC1D31 ALOX5 MX2

1.57e-042001135f11ae9055e72c938b6c9e52701478b2eee681ac4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal|6m / Sample Type, Dataset, Time_group, and Cell type.

KRT18 DSP CCDC141 LMO7 CCDC65

1.57e-04200113513ec8afea86e4a10599c924871ba4e325b0a8013
ToppCellControl-Epithelial_alveolar-Mes-Like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PARP11 AADAC LMO7 ZNF589

2.17e-041161134df7609503782d8d7e4f31ed2a626916e5474d5bc
ToppCelldroplet-Lung-1m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l14|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLXNB2 RECQL5 PANK4 OSGIN2

3.56e-04132113414a512f433315892bf0326419f23d0d5919d01ec
ToppCell356C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TFEC CCDC57 ZNF589 ARHGAP20

3.98e-041361134edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell356C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TFEC CCDC57 ZNF589 ARHGAP20

3.98e-04136113403e4e2353c23ceffde35b2d0aadd15299e3db09f
Diseasecutaneous melanoma, hair color

PPFIBP2 PLXNB2 LMO7 ARHGAP20

7.48e-05621064EFO_0000389, EFO_0003924
Diseaseanti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine

ADA2 FMNL3

6.88e-04111062EFO_0803358, EFO_0803362
Diseasecutaneous melanoma

RAB11FIP2 PLXNB2 PARP1 MX2

9.68e-041211064EFO_0000389
Diseasehematologic cancer (implicated_via_orthology)

CUX2 CUX1

9.72e-04131062DOID:2531 (implicated_via_orthology)
DiseaseShort Rib-Polydactyly Syndrome

IFT172 NEK1

9.72e-04131062C0036996
DiseaseAcute Cerebrovascular Accidents

HTR4 PRPF8 MMP12

9.78e-04541063C0751956
DiseaseSaldino-Noonan Syndrome

IFT172 NEK1

1.13e-03141062C0036069
DiseaseMajewski Syndrome

IFT172 NEK1

1.13e-03141062C0024507
DiseaseCerebrovascular accident

HTR4 PRPF8 MMP12

1.46e-03621063C0038454
DiseaseHeadache

SNX27 PLEKHA1 CUX1

1.60e-03641063HP_0002315
Diseaseinterstitial lung disease

DSP PPFIBP2 IVD

1.83e-03671063EFO_0004244
Diseasediet measurement, HOMA-B

FAT3 RAB11FIP2

2.10e-03191062EFO_0004469, EFO_0008111
DiseaseAntihypertensive use measurement

HTR4 CCDC141 RSRC1 PLEKHA1 ENPEP

2.73e-032651065EFO_0009927
Diseaseliver cirrhosis (is_marker_for)

KRT18 PARP1 GRK2

3.25e-03821063DOID:5082 (is_marker_for)
DiseaseCleft palate, cleft lip

CUX2 KRT18 CRTAC1 SFI1 STK24

3.40e-032791065EFO_0003959, HP_0000175

Protein segments in the cluster

PeptideGeneStartEntry
EEARYWAKKLEQLNA

UNC13A

136

Q9UPW8
LALQRRADAKLWKNY

CEP295NL

91

Q96MC4
LLYEKNEVKARDREW

CACNA1A

1421

O00555
NEVKARDREWKKYEF

CACNA1A

1426

O00555
ERWIRAKYEQKLFLA

AGAP3

726

Q96P47
FKHRIKEQEDYIRDW

CEP170

1281

Q5SW79
KIRYVWNDLEKRFQK

ATP13A5

136

Q4VNC0
QHEKWYQKFLALEER

CCDC112

206

Q8NEF3
QFEDVYNALRWFLRK

AADAC

156

P22760
QDLWEQSKEFLRYKE

ALKBH1

141

Q13686
DLWRKFQDVLKNYTD

CCDC65

221

Q8IXS2
LKDERVYWKQVARNL

FGFBP1

106

Q14512
YWKRFDLRRLQKELN

CUX2

11

O14529
VQWKKELRDAYREAQ

GRK2

641

P25098
YNLDEENRFRTLKWL

HJURP

396

Q8NCD3
REKEAAYQERLKNWE

RBM25

451

P49756
AYQERLKNWEIRERK

RBM25

456

P49756
WRYQELRIEKRKQEE

ANKRD33

431

Q7Z3H0
RNQVFLFKDDKYWLI

MMP12

341

P39900
KLQLLEDDKENRYWI

PARP1

571

P09874
VKKQELRFIQYWQER

GOLGA8S

466

H3BPF8
YLQWILDKQDLLKER

CCNC

11

P24863
IRVILKLYEQWKNFD

CCNC

231

P24863
LVWKNDYRQLEKELQ

ANKRD13A

16

Q8IZ07
LFLEFWKRRQAELEY

ANO6

391

Q4KMQ2
RKNREELDKYWSQQI

KRT18

261

P05783
QRAEDNEAKWKREIY

NEK1

456

Q96PY6
LLKYRWRKLEEEEQA

LEMD2

396

Q8NC56
ELEWQNRFSDYEKRK

LRSAM1

246

Q6UWE0
YARKALDFLWEKRQR

EDEM3

251

Q9BZQ6
YWKRFDLQQLQRELD

CUX1

11

Q13948
RQNWVKKIRYVIFDE

DDX60

876

Q8IY21
WRKSQQAEREYEKIK

PLXNB2

1221

O15031
RWKQYLEDERIALFL

CUEDC1

226

Q9NWM3
WIKEKIYVLLRRQAQ

ERH

86

P84090
ELVKKQELRFIQYWQ

GOLGA8Q

471

H3BV12
NWKKLRIYLDERRDV

FBXO8

181

Q9NRD0
QNFEDLERKYWKNRI

KDM4D

116

Q6B0I6
QEKYQREQEKLREEW

LMO7

1246

Q8WWI1
RYWQKILVDRQAKLN

LARP7

531

Q4G0J3
KYLKREENFLPWQRV

ENPEP

681

Q07075
IDRSNEFKNLREFWK

IVD

71

P26440
FIQVKRGRNWRDVYK

GARIN1B

81

Q96KD3
RLQARKWLEEQLKQY

GOLGA3

151

Q08378
KWLEEQLKQYRVKRQ

GOLGA3

156

Q08378
EKLRWTFNLYDINKD

KCNIP1

136

Q9NZI2
ELENERNQYEWKLKA

PPFIBP2

221

Q8ND30
WKKAIYILDLQDRNT

IFT172

896

Q9UG01
VDAAERAEKFRQKYW

PANK4

471

Q9NVE7
RIQNLDLWEFFCRKK

PARP11

171

Q9NR21
EKSNFIKRNWEIRGY

OSGIN2

226

Q9Y236
IKYAQWEESLKEIQR

CRNKL1

246

Q9BZJ0
QKAEFIFEWLRYLEK

HEATR5A

21

Q86XA9
RRQLDKYLKQQWQEL

CCDC141

231

Q6ZP82
DWKDLNLKFVLQVYR

GBA2

616

Q9HCG7
KARLLRQYDNEKKWD

FMNL3

51

Q8IVF7
AWLKLQQEFYEEKRR

BCL9

471

O00512
KAEFQEEAKRRWEYE

DSP

1331

P15924
IKRWQAIYKQFDTDR

CAPNS1

171

P04632
LNEYKIKERKQIDWE

FAT3

321

Q8TDW7
EKLLEWENNRLYHKL

CHIC2

116

Q9UKJ5
WDRQLRKIKTNYFIV

HTR4

46

Q13639
KWILLEDYRKRVQNV

ADA2

161

Q9NZK5
REQYENLKWTLERKL

CCDC57

146

Q2TAC2
GIKQFYINVEREEWK

EIF4A2

246

Q14240
TDKLFKFRNNRWEDI

CRTAC1

146

Q9NQ79
LLKKQELRFIQYWQE

GOLGA8R

471

I6L899
ELVKKQELRFIQYWQ

GOLGA8O

471

A6NCC3
KEEAQWVRKYFREEQ

FAM111B

406

Q6SJ93
RKEDEYRRNIWKGFL

SLC13A3

221

Q8WWT9
NWDYRKKAIIQEILS

CNOT6

216

Q9ULM6
EQKDKWLSLLQRYIN

ARHGAP20

171

Q9P2F6
ERFLNQIKVQEKYVW

DAP3

196

P51398
WLEDQKIRHYKIEDR

RTRAF

31

Q9Y224
YEQRLLRKVFEEWKE

SFI1

116

A8K8P3
KRRFLKAWLEYLQVR

SFI1

286

A8K8P3
KLFRFDAEVRQWKER

RGPD4

1066

Q7Z3J3
LYLANLRENWEEVKK

RPE65

341

Q16518
KKDELQSERNYLWRE

SMC3

461

Q9UQE7
WKKVDNDYNALRERL

URI1

51

O94763
VEDEAWYQKQELLRK

TBC1D31

721

Q96DN5
WYQKQELLRKAEETR

TBC1D31

726

Q96DN5
SIIKQLKDVFERDWY

PLD5

481

Q8N7P1
KYNWKLDEARKNLLR

FARSA

311

Q9Y285
QLVRIEKRKYWLNDD

ALOX5

66

P09917
QLETALKWRNYEVKL

MOV10

326

Q9HCE1
LTELIDRYKRWKAEQ

STK24

296

Q9Y6E0
FIVALNKIDRLYDWK

EIF5B

751

O60841
ELVKKQELRFIQYWQ

GOLGA8M

471

H3BSY2
KQLTYEEQDLVWKFR

PIK3C3

306

Q8NEB9
EFARWKVNNLALERK

BRINP2

91

Q9C0B6
RLKLEVQKYEAWLAE

TRIP10

456

Q15642
IDENQDRYIKKLAKW

CNDP2

11

Q96KP4
GEKFRQWKEQNRELY

CNKSR1

651

Q969H4
RDEAHKREWNLFYQK

RECQL5

496

O94762
WRVRTDFKQYQVLKQ

PRPF8

1436

Q6P2Q9
ERRYFKQQEVVLWRK

VPS26B

281

Q4G0F5
FKNYIKRNWRIVEDE

CSE1L

66

P55060
KQSIVWEFEKYQRLL

TRIM68

181

Q6AZZ1
VRFWDIYKKQLLAEF

WDR49

401

Q8IV35
FDVQRKYFKEALDRW

NRDC

276

O43847
RVFCELKWRKENIFQ

SNX27

516

Q96L92
NDIFEDKQRRKTEWF

RAB11FIP2

106

Q7L804
YRSRKQRQEWEVKAL

WDR46

491

O15213
DAEEKWFKRLIALRQ

RSRC1

311

Q96IZ7
EKYDKWKLQELRQFV

ZZEF1

621

O43149
NVQLDTEYRKKWDAL

STARD7

181

Q9NQZ5
VEYIKWLQKEQQRAR

TFEC

186

O14948
EAEWKRLSLEQRNLY

ZNF589

46

Q86UQ0
LDWELEQRKRLAEKY

THOC5

191

Q13769
VFKKFNWRYLVIDEA

SMARCA5

296

O60264
KNWKRRYFQLDENTI

PLEKHA1

206

Q9HB21
LIQFRDLKKYWNVDK

SLC26A7

421

Q8TE54
WERQYRKKDELQQEE

TCHH

1016

Q07283
KQRYRDEDQRSDLKW

TCHH

1211

Q07283
EDKQKNFLFLRLWDR

TRMT10C

171

Q7L0Y3
EAYLEAIRKNIEWLK

SCG3

406

Q8WXD2
ENKRYREAIQKWDEA

TTC33

71

Q6PID6
ELVKKQELRFIQYWQ

GOLGA8N

471

F8WBI6
YNKIREDFKNWVGIL

MX2

451

P20592