Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	bone sialoprotein binding	ANXA2 ANXA2P2	4.11e-06	2	41	2	GO:0044730
GeneOntologyMolecularFunction	extracellular matrix binding	SLIT2 ITGA2 ANXA2 ANXA2P2	1.50e-05	73	41	4	GO:0050840
GeneOntologyMolecularFunction	phospholipase A2 inhibitor activity	ANXA2 ANXA2P2	4.10e-05	5	41	2	GO:0019834
GeneOntologyMolecularFunction	GTPase inhibitor activity	SLIT2 IQGAP2	3.16e-04	13	41	2	GO:0005095
GeneOntologyMolecularFunction	phospholipase inhibitor activity	ANXA2 ANXA2P2	3.16e-04	13	41	2	GO:0004859
GeneOntologyMolecularFunction	S100 protein binding	ANXA2 ANXA2P2	4.25e-04	15	41	2	GO:0044548
GeneOntologyMolecularFunction	sulfur compound binding	SLC6A6 SLIT2 ITGA2 P2RX2 GNS	4.99e-04	323	41	5	GO:1901681
GeneOntologyMolecularFunction	lipase inhibitor activity	ANXA2 ANXA2P2	6.16e-04	18	41	2	GO:0055102
GeneOntologyMolecularFunction	serine-type endopeptidase inhibitor activity	ANXA2 ANXA2P2 TFPI	1.30e-03	105	41	3	GO:0004867
GeneOntologyMolecularFunction	heparan sulfate proteoglycan binding	SLIT2 ITGA2	1.61e-03	29	41	2	GO:0043395
GeneOntologyMolecularFunction	enzyme inhibitor activity	SLIT2 IQGAP2 ANXA2 ANXA2P2 TFPI	1.88e-03	435	41	5	GO:0004857
GeneOntologyMolecularFunction	laminin binding	SLIT2 ITGA2	2.21e-03	34	41	2	GO:0043236
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2 MYLIP	2.54e-07	7	41	3	GO:0032803
GeneOntologyBiologicalProcess	low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2 MYLIP	2.54e-07	7	41	3	GO:0032802
GeneOntologyBiologicalProcess	low-density lipoprotein receptor particle metabolic process	ANXA2 ANXA2P2 MYLIP	2.54e-07	7	41	3	GO:0032799
GeneOntologyBiologicalProcess	regulation of receptor catabolic process	ANXA2 ANXA2P2 MYLIP	2.61e-06	14	41	3	GO:2000644
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	3.86e-06	2	41	2	GO:1905597
GeneOntologyBiologicalProcess	regulation of plasma membrane organization	ATP8B1 ANXA2 ANXA2P2	8.12e-06	20	41	3	GO:1903729
GeneOntologyBiologicalProcess	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	1.16e-05	3	41	2	GO:1905602
GeneOntologyBiologicalProcess	negative regulation of low-density lipoprotein particle receptor catabolic process	ANXA2 ANXA2P2	1.16e-05	3	41	2	GO:0032804
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle clearance	ANXA2 ANXA2P2 MYLIP	1.43e-05	24	41	3	GO:0010988
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein particle clearance	ANXA2 ANXA2P2	2.31e-05	4	41	2	GO:1905581
GeneOntologyBiologicalProcess	negative regulation of receptor catabolic process	ANXA2 ANXA2P2	2.31e-05	4	41	2	GO:2000645
GeneOntologyBiologicalProcess	positive regulation of intracellular cholesterol transport	ANXA2 ANXA2P2	2.31e-05	4	41	2	GO:0032385
GeneOntologyBiologicalProcess	positive regulation of intracellular sterol transport	ANXA2 ANXA2P2	2.31e-05	4	41	2	GO:0032382
GeneOntologyBiologicalProcess	receptor catabolic process	ANXA2 ANXA2P2 MYLIP	3.15e-05	31	41	3	GO:0032801
GeneOntologyBiologicalProcess	positive regulation of plasma membrane repair	ANXA2 ANXA2P2	3.84e-05	5	41	2	GO:1905686
GeneOntologyBiologicalProcess	regulation of low-density lipoprotein particle receptor binding	ANXA2 ANXA2P2	3.84e-05	5	41	2	GO:1905595
GeneOntologyBiologicalProcess	positive regulation of intracellular lipid transport	ANXA2 ANXA2P2	3.84e-05	5	41	2	GO:0032379
GeneOntologyBiologicalProcess	positive regulation of low-density lipoprotein receptor activity	ANXA2 ANXA2P2	5.75e-05	6	41	2	GO:1905599
GeneOntologyBiologicalProcess	regulation of lipoprotein particle clearance	ANXA2 ANXA2P2 MYLIP	6.34e-05	39	41	3	GO:0010984
GeneOntologyBiologicalProcess	low-density lipoprotein particle clearance	ANXA2 ANXA2P2 MYLIP	7.37e-05	41	41	3	GO:0034383
GeneOntologyBiologicalProcess	regulation of receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	1.07e-04	8	41	2	GO:1905600
GeneOntologyBiologicalProcess	positive regulation of receptor binding	ANXA2 ANXA2P2	1.07e-04	8	41	2	GO:1900122
GeneOntologyBiologicalProcess	regulation of plasma membrane repair	ANXA2 ANXA2P2	1.07e-04	8	41	2	GO:1905684
GeneOntologyBiologicalProcess	mRNA transcription by RNA polymerase II	TAF2 ANXA2 ANXA2P2	1.51e-04	52	41	3	GO:0042789
GeneOntologyBiologicalProcess	mRNA transcription	TAF2 ANXA2 ANXA2P2	1.98e-04	57	41	3	GO:0009299
GeneOntologyBiologicalProcess	receptor-mediated endocytosis involved in cholesterol transport	ANXA2 ANXA2P2	2.10e-04	11	41	2	GO:0090118
GeneOntologyBiologicalProcess	positive regulation of lipoprotein particle clearance	ANXA2 ANXA2P2	2.51e-04	12	41	2	GO:0010986
GeneOntologyBiologicalProcess	regulation of intracellular sterol transport	ANXA2 ANXA2P2	2.51e-04	12	41	2	GO:0032380
GeneOntologyBiologicalProcess	regulation of intracellular cholesterol transport	ANXA2 ANXA2P2	2.51e-04	12	41	2	GO:0032383
GeneOntologyBiologicalProcess	plasma lipoprotein particle clearance	ANXA2 ANXA2P2 MYLIP	2.66e-04	63	41	3	GO:0034381
GeneOntologyBiologicalProcess	regulation of intracellular lipid transport	ANXA2 ANXA2P2	2.97e-04	13	41	2	GO:0032377
GeneOntologyBiologicalProcess	negative regulation of blood coagulation	ANXA2 ANXA2P2 TFPI	3.49e-04	69	41	3	GO:0030195
GeneOntologyBiologicalProcess	negative regulation of hemostasis	ANXA2 ANXA2P2 TFPI	3.64e-04	70	41	3	GO:1900047
GeneOntologyBiologicalProcess	negative regulation of coagulation	ANXA2 ANXA2P2 TFPI	3.95e-04	72	41	3	GO:0050819
GeneOntologyBiologicalProcess	positive regulation of receptor recycling	ANXA2 ANXA2P2	5.78e-04	18	41	2	GO:0001921
GeneOntologyBiologicalProcess	receptor metabolic process	ANXA2 ANXA2P2 MYLIP	5.79e-04	82	41	3	GO:0043112
GeneOntologyBiologicalProcess	response to activity	ITGA2 ANXA2 ANXA2P2	7.60e-04	90	41	3	GO:0014823
GeneOntologyBiologicalProcess	regulation of blood coagulation	ANXA2 ANXA2P2 TFPI	7.84e-04	91	41	3	GO:0030193
GeneOntologyBiologicalProcess	regulation of hemostasis	ANXA2 ANXA2P2 TFPI	8.36e-04	93	41	3	GO:1900046
GeneOntologyBiologicalProcess	regulation of coagulation	ANXA2 ANXA2P2 TFPI	9.16e-04	96	41	3	GO:0050818
GeneOntologyBiologicalProcess	negative regulation of wound healing	ANXA2 ANXA2P2 TFPI	9.73e-04	98	41	3	GO:0061045
GeneOntologyBiologicalProcess	regulation of receptor binding	ANXA2 ANXA2P2	1.03e-03	24	41	2	GO:1900120
GeneOntologyBiologicalProcess	regulation of plasma lipoprotein particle levels	ANXA2 ANXA2P2 MYLIP	1.12e-03	103	41	3	GO:0097006
GeneOntologyBiologicalProcess	transmission of nerve impulse	CACNG5 ITGA2 P2RX2	1.43e-03	112	41	3	GO:0019226
GeneOntologyBiologicalProcess	fibrinolysis	ANXA2 ANXA2P2	1.51e-03	29	41	2	GO:0042730
GeneOntologyBiologicalProcess	regulation of receptor recycling	ANXA2 ANXA2P2	1.73e-03	31	41	2	GO:0001919
GeneOntologyBiologicalProcess	blood coagulation	ITGA2 ANXA2 ANXA2P2 TFPI	1.73e-03	260	41	4	GO:0007596
GeneOntologyBiologicalProcess	coagulation	ITGA2 ANXA2 ANXA2P2 TFPI	1.88e-03	266	41	4	GO:0050817
GeneOntologyBiologicalProcess	hemostasis	ITGA2 ANXA2 ANXA2P2 TFPI	1.93e-03	268	41	4	GO:0007599
GeneOntologyBiologicalProcess	cell-matrix adhesion	ITGA2 ANXA2 ANXA2P2 SKAP1	1.99e-03	270	41	4	GO:0007160
GeneOntologyBiologicalProcess	negative regulation of response to wounding	ANXA2 ANXA2P2 TFPI	2.00e-03	126	41	3	GO:1903035
GeneOntologyBiologicalProcess	plasma membrane repair	ANXA2 ANXA2P2	2.08e-03	34	41	2	GO:0001778
GeneOntologyBiologicalProcess	substrate-dependent cell migration	SLIT2 ITGA2	2.20e-03	35	41	2	GO:0006929
GeneOntologyBiologicalProcess	intracellular cholesterol transport	ANXA2 ANXA2P2	2.33e-03	36	41	2	GO:0032367
GeneOntologyCellularComponent	AnxA2-p11 complex	ANXA2 ANXA2P2	1.12e-05	3	41	2	GO:1990665
GeneOntologyCellularComponent	PCSK9-AnxA2 complex	ANXA2 ANXA2P2	1.12e-05	3	41	2	GO:1990667
GeneOntologyCellularComponent	myelin sheath adaxonal region	ANXA2 ANXA2P2	7.83e-05	7	41	2	GO:0035749
GeneOntologyCellularComponent	pinosome	ANXA2 ANXA2P2	2.04e-04	11	41	2	GO:0044352
GeneOntologyCellularComponent	macropinosome	ANXA2 ANXA2P2	2.04e-04	11	41	2	GO:0044354
GeneOntologyCellularComponent	cell surface	SLIT2 CP ITGA2 IQGAP2 P2RX2 ANXA2 ANXA2P2 VCAN TFPI	2.45e-04	1111	41	9	GO:0009986
GeneOntologyCellularComponent	Schmidt-Lanterman incisure	ANXA2 ANXA2P2	5.01e-04	17	41	2	GO:0043220
GeneOntologyCellularComponent	plasma membrane protein complex	SLC6A6 CACNG5 ITGA2 CACNA2D2 ANXA2 ANXA2P2 SKAP1	7.56e-04	785	41	7	GO:0098797
GeneOntologyCellularComponent	compact myelin	ANXA2 ANXA2P2	7.70e-04	21	41	2	GO:0043218
GeneOntologyCellularComponent	vacuole	CYLC1 CP PLBD1 ANXA2 GNS ANXA2P2 VCAN	1.82e-03	913	41	7	GO:0005773
Domain	CTCK_1	MUC19 SLIT2	6.04e-04	18	38	2	PS01185
Domain	CT	MUC19 SLIT2	9.08e-04	22	38	2	SM00041
Domain	Cys_knot_C	MUC19 SLIT2	1.17e-03	25	38	2	IPR006207
Domain	CTCK_2	MUC19 SLIT2	1.17e-03	25	38	2	PS01225
Domain	-	ACCSL SGPL1	2.85e-03	39	38	2	3.40.640.10
Domain	PyrdxlP-dep_Trfase	ACCSL SGPL1	3.14e-03	41	38	2	IPR015424
Domain	PyrdxlP-dep_Trfase_major_sub1	ACCSL SGPL1	3.14e-03	41	38	2	IPR015421
Domain	VWA	ITGA2 CACNA2D2	5.79e-03	56	38	2	PF00092
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	SLIT2 CP ANXA2 ANXA2P2 VCAN TFPI	4.51e-07	248	41	6	24006456
Pubmed	Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.	ANXA2 ANXA2P2	1.36e-06	2	41	2	38092984
Pubmed	Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.	ANXA2 ANXA2P2	1.36e-06	2	41	2	21572519
Pubmed	Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.	ANXA2 ANXA2P2	1.36e-06	2	41	2	19841537
Pubmed	Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.	ANXA2 ANXA2P2	1.36e-06	2	41	2	21788340
Pubmed	The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.	ANXA2 ANXA2P2	1.36e-06	2	41	2	27371724
Pubmed	A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.	ANXA2 ANXA2P2	1.36e-06	2	41	2	21486955
Pubmed	Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.	ANXA2 ANXA2P2	1.36e-06	2	41	2	27389701
Pubmed	Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.	ANXA2 ANXA2P2	1.36e-06	2	41	2	21737841
Pubmed	Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.	ANXA2 ANXA2P2	1.36e-06	2	41	2	19536308
Pubmed	Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.	ANXA2 ANXA2P2	1.36e-06	2	41	2	31817350
Pubmed	ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.	ANXA2 ANXA2P2	1.36e-06	2	41	2	37832154
Pubmed	Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.	ANXA2 ANXA2P2	1.36e-06	2	41	2	23148505
Pubmed	Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.	ANXA2 ANXA2P2	1.36e-06	2	41	2	17360942
Pubmed	Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.	ANXA2 ANXA2P2	1.36e-06	2	41	2	19587120
Pubmed	Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.	ANXA2 ANXA2P2	1.36e-06	2	41	2	19580511
Pubmed	Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.	ANXA2 ANXA2P2	1.36e-06	2	41	2	30902828
Pubmed	Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.	ANXA2 ANXA2P2	1.36e-06	2	41	2	19022301
Pubmed	Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.	ANXA2 ANXA2P2	1.36e-06	2	41	2	24742684
Pubmed	Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.	ANXA2 ANXA2P2	1.36e-06	2	41	2	32687500
Pubmed	Versican G3 domain promotes blood coagulation through suppressing the activity of tissue factor pathway inhibitor-1.	VCAN TFPI	1.36e-06	2	41	2	16431924
Pubmed	Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.	ANXA2 ANXA2P2	1.36e-06	2	41	2	22453828
Pubmed	ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.	ANXA2 ANXA2P2	1.36e-06	2	41	2	38290972
Pubmed	Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.	ANXA2 ANXA2P2	1.36e-06	2	41	2	38253182
Pubmed	The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.	ANXA2 ANXA2P2	1.36e-06	2	41	2	3013423
Pubmed	Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.	ANXA2 ANXA2P2	1.36e-06	2	41	2	35064931
Pubmed	Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.	ANXA2 ANXA2P2	1.36e-06	2	41	2	28130864
Pubmed	Agents that bind annexin A2 suppress ocular neovascularization.	ANXA2 ANXA2P2	1.36e-06	2	41	2	20607799
Pubmed	A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.	ANXA2 ANXA2P2	1.36e-06	2	41	2	31253864
Pubmed	Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.	ANXA2 ANXA2P2	1.36e-06	2	41	2	36739096
Pubmed	Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.	ANXA2 ANXA2P2	1.36e-06	2	41	2	17549680
Pubmed	Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.	ANXA2 ANXA2P2	1.36e-06	2	41	2	22517898
Pubmed	Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.	ANXA2 ANXA2P2	1.36e-06	2	41	2	22185818
Pubmed	Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.	ANXA2 ANXA2P2	1.36e-06	2	41	2	39384746
Pubmed	Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.	ANXA2 ANXA2P2	1.36e-06	2	41	2	30462534
Pubmed	Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.	ANXA2 ANXA2P2	1.36e-06	2	41	2	19628708
Pubmed	Annexin A2 binds to the localization signal in the 3' untranslated region of c-myc mRNA.	ANXA2 ANXA2P2	1.36e-06	2	41	2	15654879
Pubmed	Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.	ANXA2 ANXA2P2	1.36e-06	2	41	2	20826156
Pubmed	Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.	ANXA2 ANXA2P2	1.36e-06	2	41	2	20847146
Pubmed	Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.	ANXA2 ANXA2P2	1.36e-06	2	41	2	27468426
Pubmed	Complete structure of the murine p36 (annexin II) gene. Identification of mRNAs for both the murine and the human gene with alternatively spliced 5' noncoding exons.	ANXA2 ANXA2P2	4.06e-06	3	41	2	8634333
Pubmed	STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.	ANXA2 ANXA2P2	4.06e-06	3	41	2	35098646
Pubmed	RNASEH1-AS1 induced by H3K27ac stabilizes ANXA2 mRNA to promote the progression of colorectal cancer through recruiting BUD13.	ANXA2 ANXA2P2	4.06e-06	3	41	2	38053379
Pubmed	Annexin A2 promotes angiogenesis after ischemic stroke via annexin A2 receptor - AKT/ERK pathways.	ANXA2 ANXA2P2	4.06e-06	3	41	2	36367512
Pubmed	Revealing Annexin A2 and ARF-6 enrollment during Trypanosoma cruzi extracellular amastigote-host cell interaction.	ANXA2 ANXA2P2	4.06e-06	3	41	2	26416603
Pubmed	Chromosomal localization of the human genes for lipocortin I and lipocortin II.	ANXA2 ANXA2P2	4.06e-06	3	41	2	2969496
Pubmed	Annexin A2 depletion delays EGFR endocytic trafficking via cofilin activation and enhances EGFR signaling and metastasis formation.	ANXA2 ANXA2P2	4.06e-06	3	41	2	23792445
Pubmed	The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.	ANXA2 ANXA2P2	4.06e-06	3	41	2	35413401
Pubmed	Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.	ANXA2 ANXA2P2	4.06e-06	3	41	2	37690046
Pubmed	Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases.	ANXA2 ANXA2P2	4.06e-06	3	41	2	28694388
Pubmed	Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche.	ANXA2 ANXA2P2	4.06e-06	3	41	2	21108988
Pubmed	The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.	ANXA2 ANXA2P2	4.06e-06	3	41	2	27045038
Pubmed	Accumulation of annexin A2 and S100A10 prevents apoptosis of apically delaminated, transformed epithelial cells.	ANXA2 ANXA2P2	4.06e-06	3	41	2	37844241
Pubmed	High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2.	ANXA2 ANXA2P2	4.06e-06	3	41	2	27470587
Pubmed	Annexin 2-CXCL12 interactions regulate metastatic cell targeting and growth in the bone marrow.	ANXA2 ANXA2P2	4.06e-06	3	41	2	25139998
Pubmed	Annexins--unique membrane binding proteins with diverse functions.	ANXA2 ANXA2P2	4.06e-06	3	41	2	15169834
Pubmed	Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9.	ANXA2 ANXA2P2	4.06e-06	3	41	2	24808179
Pubmed	Hepatic Overexpression of Annexin A1 and A2 in Thioacetamide-Primed Mice Protects Them Against Acetaminophen-Induced Liver Failure and Death.	ANXA2 ANXA2P2	4.06e-06	3	41	2	27451051
Pubmed	Impaired osteoblast differentiation in annexin A2- and -A5-deficient cells.	ANXA2 ANXA2P2	4.06e-06	3	41	2	25222280
Pubmed	The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway.	ANXA2 ANXA2P2	4.06e-06	3	41	2	26963384
Pubmed	Macrophage surface expression of annexins I and II in the phagocytosis of apoptotic lymphocytes.	ANXA2 ANXA2P2	4.06e-06	3	41	2	15064349
Pubmed	Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle.	ANXA2 ANXA2P2	4.06e-06	3	41	2	28334824
Pubmed	Tenascin-c renders a proangiogenic phenotype in macrophage via annexin II.	ANXA2 ANXA2P2	4.06e-06	3	41	2	28857429
Pubmed	FOXQ1 promotes the osteogenic differentiation of bone mesenchymal stem cells via Wnt/β-catenin signaling by binding with ANXA2.	ANXA2 ANXA2P2	4.06e-06	3	41	2	32943107
Pubmed	Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B.	ANXA2 ANXA2P2	4.06e-06	3	41	2	31160583
Pubmed	Prostaglandin-endoperoxide synthase-2 deletion affects the natural trafficking of Annexin A2 in monocytes and favours venous thrombosis in mice.	ANXA2 ANXA2P2	4.06e-06	3	41	2	28536720
Pubmed	Inhibition of ANXA2 regulated by SRF attenuates the development of severe acute pancreatitis by inhibiting the NF-κB signaling pathway.	ANXA2 ANXA2P2	4.06e-06	3	41	2	35900381
Pubmed	Annexin II is a thiazolidinedione-responsive gene involved in insulin-induced glucose transporter isoform 4 translocation in 3T3-L1 adipocytes.	ANXA2 ANXA2P2	4.06e-06	3	41	2	14726447
Pubmed	Annexin II interactions with the annexin II receptor enhance multiple myeloma cell adhesion and growth in the bone marrow microenvironment.	ANXA2 ANXA2P2	4.06e-06	3	41	2	22223826
Pubmed	Annexin A2 promotes phagophore assembly by enhancing Atg16L⁺ vesicle biogenesis and homotypic fusion.	ANXA2 ANXA2P2	4.06e-06	3	41	2	25597631
Pubmed	Mitochondrially mediated integrin αIIbβ3 protein inactivation limits thrombus growth.	ANXA2 ANXA2P2	4.06e-06	3	41	2	24014035
Pubmed	Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity.	ANXA2 ANXA2P2	4.06e-06	3	41	2	28283478
Pubmed	Annexin A2 regulates TRPA1-dependent nociception.	ANXA2 ANXA2P2	4.06e-06	3	41	2	25355205
Pubmed	Plasminogen-stimulated inflammatory cytokine production by airway smooth muscle cells is regulated by annexin A2.	ANXA2 ANXA2P2	8.12e-06	4	41	2	23721211
Pubmed	A cis-acting region in the N-methyl-d-aspartate R1 3'-untranslated region interacts with the novel RNA-binding proteins beta subunit of alpha glucosidase II and annexin A2--effect of chronic ethanol exposure in vivo.	ANXA2 ANXA2P2	8.12e-06	4	41	2	21995826
Pubmed	Annexin A2 tetramer activates human and murine macrophages through TLR4.	ANXA2 ANXA2P2	8.12e-06	4	41	2	19965653
Pubmed	Modulation of prostaglandin transport activity of SLCO2A1 by annexin A2 and S100A10.	ANXA2 ANXA2P2	8.12e-06	4	41	2	38372137
Pubmed	A new cis-acting motif is required for the axonal SMN-dependent Anxa2 mRNA localization.	ANXA2 ANXA2P2	8.12e-06	4	41	2	28258160
Pubmed	Regulation of the SHP-2 tyrosine phosphatase by a novel cholesterol- and cell confluence-dependent mechanism.	ANXA2 ANXA2P2	8.12e-06	4	41	2	12611902
Pubmed	Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo.	ANXA2 ANXA2P2	8.12e-06	4	41	2	14702107
Pubmed	Annexin A2 is a Robo4 ligand that modulates ARF6 activation-associated cerebral trans-endothelial permeability.	ANXA2 ANXA2P2	8.12e-06	4	41	2	29786451
Pubmed	Hspb1 protects against severe acute pancreatitis by attenuating apoptosis and ferroptosis via interacting with Anxa2 to restore the antioxidative activity of Prdx1.	ANXA2 ANXA2P2	8.12e-06	4	41	2	38481805
Pubmed	PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.	IQGAP2 ANXA2	8.12e-06	4	41	2	17254974
Pubmed	Secretion of Annexin II via activation of insulin receptor and insulin-like growth factor receptor.	ANXA2 ANXA2P2	8.12e-06	4	41	2	12431980
Pubmed	Dentin phosphoprotein binds annexin 2 and is involved in calcium transport in rat kidney ureteric bud cells.	ANXA2 ANXA2P2	8.12e-06	4	41	2	23525114
Pubmed	Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation.	ANXA2 ANXA2P2	8.12e-06	4	41	2	22848640
Pubmed	Nuclear autoantigenic sperm protein facilitates glioblastoma progression and radioresistance by regulating the ANXA2/STAT3 axis.	ANXA2 ANXA2P2	8.12e-06	4	41	2	38605477
Pubmed	Disruption of the nuclear hormone receptor RORalpha in staggerer mice.	ANXA2 ANXA2P2	8.12e-06	4	41	2	8602221
Pubmed	The protein-protein interaction between connective tissue growth factor and annexin A2 is relevant to pannus formation in rheumatoid arthritis.	ANXA2 ANXA2P2	8.12e-06	4	41	2	34702315
Pubmed	The annexins: specific markers of midline structures and sensory neurons in the developing murine central nervous system.	ANXA2 ANXA2P2	8.12e-06	4	41	2	7706559
Pubmed	Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transport.	ANXA2 ANXA2P2	8.12e-06	4	41	2	15078881
Pubmed	Blockade of Annexin A2 Prevents Early Microvasculopathy in Murine Models of Diabetic Retinopathy.	ANXA2 ANXA2P2	8.12e-06	4	41	2	37103008
Pubmed	Endothelial cell annexin A2 regulates polyubiquitination and degradation of its binding partner S100A10/p11.	ANXA2 ANXA2P2	8.12e-06	4	41	2	18434302
Pubmed	Structure of an asymmetric ternary protein complex provides insight for membrane interaction.	ANXA2 ANXA2P2	8.12e-06	4	41	2	22940583
Pubmed	Characterization of the human lipocortin-2-encoding multigene family: its structure suggests the existence of a short amino acid unit undergoing duplication.	ANXA2 ANXA2P2	8.12e-06	4	41	2	2174397
Pubmed	Feedback regulation of endothelial cell surface plasmin generation by PKC-dependent phosphorylation of annexin A2.	ANXA2 ANXA2P2	8.12e-06	4	41	2	21115493
Pubmed	The Npc1 mutation causes an altered expression of caveolin-1, annexin II and protein kinases and phosphorylation of caveolin-1 and annexin II in murine livers.	ANXA2 ANXA2P2	8.12e-06	4	41	2	10036317
Pubmed	Annexin A2 is a C-terminal PCSK9-binding protein that regulates endogenous low density lipoprotein receptor levels.	ANXA2 ANXA2P2	8.12e-06	4	41	2	18799458
Pubmed	SIRT6 Is a Target of Regulation by UBE3A That Contributes to Liver Tumorigenesis in an ANXA2-Dependent Manner.	ANXA2 ANXA2P2	8.12e-06	4	41	2	29217762
Pubmed	Annexin A2 binds to endosomes and negatively regulates TLR4-triggered inflammatory responses via the TRAM-TRIF pathway.	ANXA2 ANXA2P2	1.35e-05	5	41	2	26527544
GeneFamily	Calcium voltage-gated channel subunits	CACNG5 CACNA2D2	6.33e-04	26	26	2	253
Coexpression	STAMBOLSKY_RESPONSE_TO_VITAMIN_D3_UP	CYLC1 CP ITGA2 P2RX2 DNAH17	2.05e-07	84	41	5	M2103
Coexpression	MEK_UP.V1_DN	POLI ELOVL5 PLBD1 ATP8B1 TAF2 TFPI	5.51e-07	194	41	6	M2724
Coexpression	GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN	PLBD1 IQGAP2 ANXA2 GNS ANXA2P2 VCAN	6.59e-07	200	41	6	M4486
Coexpression	GSE22886_NEUTROPHIL_VS_MONOCYTE_DN	EIF3D ANXA2 GNS ANXA2P2 VCAN	1.44e-05	199	41	5	M4467
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN	PLBD1 ANXA2 GNS ANXA2P2 VCAN	1.47e-05	200	41	5	M4506
Coexpression	GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN	ELOVL5 PLBD1 ANXA2 ANXA2P2 VCAN	1.47e-05	200	41	5	M4971
Coexpression	GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN	PLBD1 ANXA2 GNS ANXA2P2 VCAN	1.47e-05	200	41	5	M4496
Coexpression	MURARO_PANCREAS_ACINAR_CELL	TSPAN6 ATP8B1 TNFAIP1 EIF3D ITGA2 IQGAP2 TRAM1 TFPI	1.51e-05	732	41	8	M39174
Coexpression	TABULA_MURIS_SENIS_SUBCUTANEOUS_ADIPOSE_TISSUE_B_CELL_AGEING	ERGIC1 ANXA2 GNS ANXA2P2	5.39e-05	132	41	4	MM3822
Coexpression	BROWNE_HCMV_INFECTION_2HR_DN	STIP1 ITGA2 ANXA2	5.85e-05	48	41	3	M521
Coexpression	ZHANG_UTERUS_C0_MATURATIONAL_UP	ANXA2 ANXA2P2	6.64e-05	8	41	2	MM16603
Coexpression	HE_LIM_SUN_FETAL_LUNG_C6_MUC16_POS_CILIATED_CELL	CP ITGA2 VCAN	1.26e-04	62	41	3	M45790
Coexpression	MURARO_PANCREAS_DUCTAL_CELL	TSPAN6 ERGIC1 ATP8B1 ITGA2 IQGAP2 ANXA2 GNS ANXA2P2 TFPI	1.27e-04	1276	41	9	M39173
Coexpression	GERHOLD_ADIPOGENESIS_DN	ANXA2 ANXA2P2 VCAN	1.39e-04	64	41	3	MM671
Coexpression	GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_DN	TSPAN6 PLBD1 TNFAIP1 DNAH17	1.50e-04	172	41	4	M5642
Coexpression	RUBENSTEIN_SKELETAL_MUSCLE_FAP_CELLS	ANXA2 TRAM1 VCAN TFPI	1.75e-04	179	41	4	M41745
Coexpression	YAMAZAKI_TCEB3_TARGETS_UP	ANXA2 GNS ANXA2P2 TFPI	1.75e-04	179	41	4	MM660
Coexpression	GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN	ELOVL5 SLC6A6 IQGAP2 ANXA2	2.57e-04	198	41	4	M3119
Coexpression	GSE25087_TREG_VS_TCONV_ADULT_UP	ELOVL5 ANXA2 ANXA2P2 SKAP1	2.62e-04	199	41	4	M4650
Coexpression	GSE3982_EOSINOPHIL_VS_BASOPHIL_DN	EIF3D TRAM1 ANXA2P2 SKAP1	2.62e-04	199	41	4	M5414
Coexpression	GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP	IQGAP2 ANXA2 TRAM1 ANXA2P2	2.62e-04	199	41	4	M3194
Coexpression	GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_UP	ERGIC1 CP PLBD1 VCAN	2.67e-04	200	41	4	M5100
Coexpression	GSE17721_POLYIC_VS_CPG_6H_BMDC_DN	PER3 VCAN TFPI MYLIP	2.67e-04	200	41	4	M3944
Coexpression	MCLACHLAN_DENTAL_CARIES_DN	POLI SLIT2 PER3	2.89e-04	82	41	3	M1278
Coexpression	MENON_FETAL_KIDNEY_4_PODOCYTES	RFC1 IQGAP2 ANXA2 ANXA2P2	2.99e-04	206	41	4	M39254
Coexpression	HU_FETAL_RETINA_FIBROBLAST	PLBD1 ANXA2 VCAN TFPI MYLIP	3.23e-04	385	41	5	M39264
Coexpression	ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE	CP ANXA2 ANXA2P2	3.32e-04	86	41	3	MM1209
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Krt80\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TSPAN6 SLIT2 IQGAP2 SKAP1 MYLIP	1.93e-07	141	41	5	40ef6d792e11fe10963d64eb0b606b90556c1a70
ToppCell	RA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	SLIT2 ANXA2 VCAN TFPI CCDC138	9.84e-07	196	41	5	e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLIT2 CP P2RX2 VCAN TFPI	1.09e-06	200	41	5	6f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLIT2 CP P2RX2 VCAN TFPI	1.09e-06	200	41	5	3a164e3971bcd62b148b813171c103adb81f972e
ToppCell	Basal_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	TSPAN6 ATP8B1 ITGA2 ZNF484	1.79e-05	170	41	4	776d4224a682b6c648041827efd69794f88906f0
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLIT2 CP RFC1 VCAN	2.05e-05	176	41	4	cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCell	RA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	SLIT2 ANXA2 VCAN CCDC138	2.28e-05	181	41	4	2b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFAP54 P2RX2 ANXA2 TFPI	2.33e-05	182	41	4	8d8f28bd43108b2fb3a6c2a3d77a897853d440a4
ToppCell	droplet-Marrow-nan-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOVL5 ERGIC1 CP PER3	2.38e-05	183	41	4	b5782b18decfe85026acf42daac0670d92385861
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOVL5 ERGIC1 CP PER3	2.38e-05	183	41	4	e32847cfebba7c8bb2026e33c3c85f64819460a9
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	CP ATP8B1 VCAN TFPI	2.71e-05	189	41	4	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	control-Myeloid-CD14_Monocytes_2\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PLBD1 ANXA2 GNS VCAN	2.76e-05	190	41	4	47513757e0059e8370e49672a577f25ca842e98c
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	CYLC1 ANXA2 VCAN TFPI	2.82e-05	191	41	4	b5328733da3d3d77c4f6fc5e2ba2035f8898f172
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	CP CFAP54 VCAN TFPI	2.94e-05	193	41	4	ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCell	Non-neuronal-Non-dividing\|World / Primary Cells by Cluster	TSPAN6 IQGAP2 ANXA2 TFPI	3.00e-05	194	41	4	0add09d97192b34bd506209ab5f1a77182f498fc
ToppCell	Non-neuronal-Non-dividing-Radial_Glia\|World / Primary Cells by Cluster	TSPAN6 IQGAP2 ANXA2 TFPI	3.00e-05	194	41	4	1445b7611c2b1ab9b320f330d17d70117892cc28
ToppCell	COVID-19_Mild-PLT_5\|COVID-19_Mild / Disease Group and Platelet Clusters	PLBD1 RFC1 ANXA2 VCAN	3.06e-05	195	41	4	bdf9a6ea1bd83c72a834c45f86ce3f4643a9bef3
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_3\|Classical_Monocyte / Disease condition and Cell class	PLBD1 IQGAP2 ANXA2 VCAN	3.12e-05	196	41	4	15397ec27167bb2fb6fec120b68bf38fc71b2670
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PLBD1 ANXA2 GNS VCAN	3.12e-05	196	41	4	28e9e191361966df3a9bd48450090577aa72a999
ToppCell	(7)_Monocyte\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PLBD1 ANXA2 GNS VCAN	3.12e-05	196	41	4	0232167559dcd2d86ee8b78017cf5f2a084b2cb7
ToppCell	(7)_MNP-(7)_Monocyte\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PLBD1 ANXA2 GNS VCAN	3.12e-05	196	41	4	4c2ea16352ba3482c02c03866460e0d975f9fc99
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CP ITGA2 ANXA2 TMPRSS11E	3.12e-05	196	41	4	279f43deeba4528cd63f5217a8441b5452bf0b16
ToppCell	URO-Myeloid-CD14_Mono\|URO / Disease, Lineage and Cell Type	PLBD1 ANXA2 GNS VCAN	3.18e-05	197	41	4	45c16125fa32e50304fdd45a7cb457488bd50ee3
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma\|TCGA-Pancreas / Sample_Type by Project: Shred V9	TSPAN6 PLBD1 ANXA2 TFPI	3.18e-05	197	41	4	d8355f07a53e771052f9ab6b38814365dfe8d9ae
ToppCell	(7)_MNP\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PLBD1 ANXA2 GNS VCAN	3.18e-05	197	41	4	6790346736946984cc80d67668523ba70ab0b380
ToppCell	BLOOD--(3)_Classical_Mono-2\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	34c23181c227f65209cde4382248253282f6ac6e
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	cf0fda1a24449cfd8ed56ffc7841d8accb187949
ToppCell	PBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	d347462ba6cb1c5a59c86dffbbe914cbc1e9cf16
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CP ITGA2 ANXA2 TMPRSS11E	3.24e-05	198	41	4	eaeb70c0f7f7ca21f7d5bc5ea6c7c1a49a293c45
ToppCell	Multiple_Sclerosis-Myeloid\|Multiple_Sclerosis / Disease, Lineage and Cell Type	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	3c2817d95011ae372d0316ccf774e975536207b0
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLIT2 CP VCAN TFPI	3.24e-05	198	41	4	0f4052a59c6bd89dab637d6ef1214460d6cbcf55
ToppCell	PBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	c5a22846bccff948f90bc1d5fe309907dcd08348
ToppCell	COVID-19_Mild-Myeloid-Classical_Monocyte\|COVID-19_Mild / Disease group, lineage and cell class	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	e78d027a095473af555762a4d542a73f5bb2e166
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC6A6 ANXA2 GNS VCAN	3.24e-05	198	41	4	c26c909e95225440abdf558b1b858ffc06177000
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	7e1f08dae11a7cc7949a5622d82c7e6660d06dea
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	525adc91fd8f2ad957b1879a5bf3950baa7d5ef8
ToppCell	PBMC-Mild-Myeloid-Classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	c49c71b34151d82b8795763bcb633c301c35f659
ToppCell	NS-critical-d_07-13\|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSPAN6 CP ATP8B1 ANXA2	3.24e-05	198	41	4	a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	70e62d815b2a0aa5327ff94d6f4d503176e007b9
ToppCell	COVID-19_Severe-Myeloid-Classical_Monocyte\|COVID-19_Severe / Disease group, lineage and cell class	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	dfe92577c7d1e63315c7564d5d99362c6e7d4d46
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	0128d00e6c3f99a026329dd169c0ea5e0e24c59c
ToppCell	Fibroblasts-HLA-DRA_high_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SLIT2 CP VCAN TFPI	3.24e-05	198	41	4	e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	f3346c26b9647a199faf3cd7ab19c3a963dbabc2
ToppCell	Non-neuronal-Dividing-Radial_Glia-vRG-20\|World / Primary Cells by Cluster	ITGA2 IQGAP2 ANXA2 TFPI	3.24e-05	198	41	4	bce0bc1e3f2257e0f42a1fa6e5b57cf71e4514ba
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CP ITGA2 ANXA2 TMPRSS11E	3.24e-05	198	41	4	9ec0ed556860e5543d327f4bf2370efc571ad75e
ToppCell	PBMC-Mild-Myeloid-Classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	4780f0276546962a2fc9f1041cfe49d2919d72b2
ToppCell	severe_COVID-19-Classical_Monocyte\|severe_COVID-19 / disease group, cell group and cell class (v2)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	40dd3333945aa0c9120296b75155c621f462dbe8
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Monocytic-Classical_monocytes\|lymph-node_spleen / Manually curated celltypes from each tissue	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	187a04d498f0b355cb11c81172721698818082d6
ToppCell	Multiple_Sclerosis-Myeloid-CD14_Mono\|Multiple_Sclerosis / Disease, Lineage and Cell Type	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	128969698b2b0468cf5374f695e2d9fd02227d13
ToppCell	PBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	51c220507bb05aa6338fec494b8ecf4902437708
ToppCell	mild_COVID-19-Classical_Monocyte\|mild_COVID-19 / disease group, cell group and cell class (v2)	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	5b31b6e008e05d6528656114fbe0ccae8ffe13b1
ToppCell	COVID-19_Severe-Classical_Monocyte\|COVID-19_Severe / disease group, cell group and cell class	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	b88c4c0ed1abf0a28dbe05b04b9bee1073855ba8
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SLC6A6 PLBD1 GNS VCAN	3.24e-05	198	41	4	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Monocytic\|lymph-node_spleen / Manually curated celltypes from each tissue	PLBD1 ANXA2 GNS VCAN	3.24e-05	198	41	4	065c8a9655d19f93dfdb453c78bbfe7d857caf3e
ToppCell	PBMC-Mild-Myeloid\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	02256d86541be6851634283047fdc05fdf095114
ToppCell	356C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ERGIC1 SLIT2 PLBD1 VCAN	3.31e-05	199	41	4	beca4c7eb29ac771fd37f30cd23d4dce4afcfff8
ToppCell	PBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	9314eb9a89407738626a0384884454b5f9031ee7
ToppCell	IIF-Myeloid-CD14_Mono\|IIF / Disease, Lineage and Cell Type	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	accfb3d8ad3f03f9302f2056ca16c1be6231a351
ToppCell	21-Trachea-Epithelial\|Trachea / Age, Tissue, Lineage and Cell class	TSPAN6 CP ITGA2 ANXA2	3.31e-05	199	41	4	8eb8b086c38960200578a9fe8853ca6e894ddee4
ToppCell	critical-Epithelial\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TSPAN6 CP ITGA2 ANXA2	3.31e-05	199	41	4	bbb44e2a52f102a6d891ead6c06d6c07221abd33
ToppCell	356C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ERGIC1 SLIT2 PLBD1 VCAN	3.31e-05	199	41	4	cd3ab9a75b40e0d417d53b3d8756fc9bed30ac83
ToppCell	3'_v3-blood-Myeloid_Monocytic\|blood / Manually curated celltypes from each tissue	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	bf3a5085a5ae50f2ef745dce0a4ca8833b9438fd
ToppCell	healthy_donor-Myeloid\|healthy_donor / Disease condition, Lineage, Cell class and subclass	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	d41994e08f7c3f5bd865b689db8f032efbe88d24
ToppCell	healthy_donor-Myeloid-Monocytic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	bd66a8d1a7cc92313328acc7c7ae0442faff951e
ToppCell	NS-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSPAN6 CP ITGA2 ANXA2	3.31e-05	199	41	4	d64adb68502be596ce55fb2cb63fe1cfa2c5f8ba
ToppCell	PBMC-Mild-Myeloid\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	27667838e065370d4536eaaf5b42ad322a714b96
ToppCell	COVID-19_Mild-Myeloid\|COVID-19_Mild / Disease group, lineage and cell class	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	d0c230c3699955a80630b63ed18c770444c5dfe5
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	87956fcb39c2e3e99622ff05f99267d7621a78fc
ToppCell	PSB-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSPAN6 CP ATP8B1 ANXA2	3.31e-05	199	41	4	58dcb0eedafa8629585dc99e53147e2287f49689
ToppCell	NS-critical-d_07-13-Epithelial\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSPAN6 CP ITGA2 ANXA2	3.31e-05	199	41	4	b88a81cd2a89f4d27100c96ae4324dcee68daf83
ToppCell	COVID-19_Severe-Classical_Monocyte\|COVID-19_Severe / Disease condition and Cell class	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	ea1e2ccde3930fab6d04a9bf130837455c742474
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC6A6 PLBD1 ANXA2 VCAN	3.31e-05	199	41	4	c40cb51c738b15d2761a50cfc8415a31a673be7f
ToppCell	COVID-19_Severe-Myeloid\|COVID-19_Severe / Disease group, lineage and cell class	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	babbf3220cc811a1794032e06c6cec4dfc7bff2f
ToppCell	NS-critical-d_16-33-Epithelial\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSPAN6 CP ITGA2 ANXA2	3.31e-05	199	41	4	3b68197ec01c5f2b315d9e9b6eb02d5f6b5b77a3
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Fibroblasts\|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X	SLIT2 TRAM1 VCAN TFPI	3.31e-05	199	41	4	f19c683f38bca3bfee40396f27423441051dec67
ToppCell	mild_COVID-19_(asymptomatic)-Classical_Monocyte\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	73a98d19871ffbc3c631de330998d42e9afa6da2
ToppCell	Int-URO\|World / Disease, Lineage and Cell Type	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	792a8717c048854952ca26cdc58d325f2ece6c1a
ToppCell	severe-Myeloid-CD14_Monocytes_1\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	ce07b7c1edfc6e2136dafcf041361b66a52271d3
ToppCell	3'_v3-blood-Myeloid_Monocytic-Classical_monocytes\|blood / Manually curated celltypes from each tissue	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	95b27f4bf1300f885b95c1a70a54252274dc8f51
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Radial_glial\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	TSPAN6 IQGAP2 ANXA2 TFPI	3.31e-05	199	41	4	6fd9774f18da3e6f114427f55a8879ac90c41350
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLIT2 PLBD1 VCAN TFPI	3.31e-05	199	41	4	137ff58897e6ada8a5a70205f66fe9110795506b
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Radial_glial-oRG\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	TSPAN6 ITGA2 IQGAP2 TFPI	3.31e-05	199	41	4	151bda6821b52cfb4491474892ecb45781522837
ToppCell	PBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	dbf0bf09896c46155ae6fbd6307f097799e7e34e
ToppCell	control-Myeloid-CD14_Monocytes_1\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PLBD1 ANXA2 GNS VCAN	3.31e-05	199	41	4	8c14237c3da91d1a4878df489a495408a1e83883
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLIT2 CP VCAN TFPI	3.31e-05	199	41	4	36883044787a9fb79cf7e83a7da8e34eea83f2f1
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CP IQGAP2 VCAN TFPI	3.31e-05	199	41	4	615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast-(8)_Fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CP IQGAP2 VCAN TFPI	3.31e-05	199	41	4	56d72da6a5fab9cbb2975fe6f87a631debaba6a8
ToppCell	Sepsis-URO-Myeloid\|URO / Disease, condition lineage and cell class	PLBD1 ANXA2 GNS VCAN	3.37e-05	200	41	4	334427a7e1b2b077b1fd33f7ce7d29d823c2f7d6
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC6A6 PLBD1 ANXA2 VCAN	3.37e-05	200	41	4	9e8659bbc6547f1ab7f4e0a81b0bcbe158e9e2f7
ToppCell	control-Epithelial\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TSPAN6 CP ITGA2 ANXA2	3.37e-05	200	41	4	f95bbb94e51ac28b1995026c599ec3a34e012916
ToppCell	MS-Multiple_Sclerosis-Myeloid-CD14+_Monocyte\|Multiple_Sclerosis / Disease, condition lineage and cell class	PLBD1 ANXA2 GNS VCAN	3.37e-05	200	41	4	172244415387e35747573c1b0a89b7e6fa7d1942
ToppCell	COVID_vent-Myeloid\|COVID_vent / Disease condition, Lineage, Cell class and subclass	PLBD1 ANXA2 GNS VCAN	3.37e-05	200	41	4	621af09aae34226902c03edf556562f3ab35a7d8
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC6A6 PLBD1 ANXA2 VCAN	3.37e-05	200	41	4	87c7c59632a8e9a7a11642f439cb700fb75bb282
ToppCell	NS-moderate-d_07-13-Epithelial\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSPAN6 CP ITGA2 ANXA2	3.37e-05	200	41	4	85940b4bf7971b872469dea8b8d7a45bdeb2a909
ToppCell	NS-control-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TSPAN6 CP ITGA2 ANXA2	3.37e-05	200	41	4	d014959891893b6d3854a471fba1dc50c6625a0a
ToppCell	Sepsis-URO-Myeloid-CD14+_Monocyte\|URO / Disease, condition lineage and cell class	PLBD1 ANXA2 GNS VCAN	3.37e-05	200	41	4	209976dbbfc1edbeb3ea128cd0453ec9572f54cb
ToppCell	COVID-19-COVID-19_Mild-Myeloid-CD14+_Monocyte\|COVID-19_Mild / Disease, condition lineage and cell class	PLBD1 ANXA2 GNS VCAN	3.37e-05	200	41	4	f76d3647f8ab5f7be018b0697c911597198e03f5
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Macroglial-Astrocyte\|3m / Sample Type, Dataset, Time_group, and Cell type.	TSPAN6 ITGA2 IQGAP2 TFPI	3.37e-05	200	41	4	98d7f577b31a603bf835bf9b4ea31999445cf0e5
ToppCell	MS-IIF-Myeloid-CD14+_Monocyte\|IIF / Disease, condition lineage and cell class	PLBD1 ANXA2 GNS VCAN	3.37e-05	200	41	4	50d874971dabd3a3b26cc859d1977ffd01fad172
ToppCell	COVID-19-COVID-19_Severe-Myeloid-CD14+_Monocyte\|COVID-19_Severe / Disease, condition lineage and cell class	PLBD1 ANXA2 GNS VCAN	3.37e-05	200	41	4	6abee30708572519045e9456dac2017b5308817a
Drug	NS-398; Up 200; 10uM; PC3; HT_HG-U133A	CYLC1 ITGA2 PER3 CACNA2D2 DNAH17 TFPI	1.40e-06	198	41	6	6892_UP
Drug	Ib-f	POLI CP	3.16e-06	2	41	2	CID000070008
Drug	s-BuLi	POLI CP ITGA2	3.62e-06	17	41	3	CID000061028
Drug	cyclopentadiene	POLI CP ITGA2	6.05e-06	20	41	3	CID000007612
Drug	2,6-diphenylphenol	POLI CP	9.48e-06	3	41	2	CID000075512
Drug	Triamterene [396-01-0]; Up 200; 15.8uM; PC3; HT_HG-U133A	TNFAIP1 ITGA2 GNS VCAN TFPI	1.69e-05	179	41	5	1819_UP
Drug	1,2-bis(dicyclohexylphosphino)ethane	POLI ITGA2	1.89e-05	4	41	2	CID000534202
Drug	bicyclo(2.2.2)octane	CP ITGA2	1.89e-05	4	41	2	CID000009235
Drug	0297417-0002B [362658-29-5]; Up 200; 10uM; PC3; HT_HG-U133A	CYLC1 ITGA2 CACNA2D2 VN1R1 TFPI	2.20e-05	189	41	5	6895_UP
Drug	Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; PC3; HT_HG-U133A	ATP8B1 TNFAIP1 VN1R1 SGPL1 VCAN	2.43e-05	193	41	5	4315_DN
Drug	Mesoridazine besylate [32672-69-8]; Down 200; 7.4uM; HL60; HG-U133A	ELOVL5 ATP8B1 TNFAIP1 TAF2 GNS	2.68e-05	197	41	5	1725_DN
Drug	Bucladesine sodium salt [16980-89-5]; Up 200; 7.8uM; PC3; HT_HG-U133A	PLBD1 TNFAIP1 VN1R1 GNS TFPI	2.75e-05	198	41	5	5886_UP
Drug	Dipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A	SLIT2 TNFAIP1 PER3 GNS TFPI	2.75e-05	198	41	5	6030_DN
Drug	Propranolol hydrochloride [318-98-9]; Down 200; 13.6uM; MCF7; HT_HG-U133A	ELOVL5 CYLC1 SLC6A6 CACNA2D2 DNAH17	2.75e-05	198	41	5	3396_DN
Drug	Ribostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; MCF7; HT_HG-U133A	ELOVL5 CYLC1 SLIT2 CACNA2D2 VN1R1	2.81e-05	199	41	5	6765_DN
Drug	Fluphenazine dihydrochloride [146-56-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A	ELOVL5 SLIT2 PER3 VN1R1 SGPL1	2.81e-05	199	41	5	7234_UP
Drug	cyclopentadienyl	POLI CP ITGA2	2.85e-05	33	41	3	CID000137443
Drug	Rhodium	POLI ITGA2 VCAN	3.12e-05	34	41	3	CID000023948
Drug	oxoniobium	POLI CP ITGA2	4.04e-05	37	41	3	CID000082838
Drug	dimidium	CP ITGA2	4.72e-05	6	41	2	CID000068207
Drug	1,2-bis(dimethylphosphino)ethane	POLI ITGA2	4.72e-05	6	41	2	CID000141059
Drug	zinc carbonate	CP ITGA2	4.72e-05	6	41	2	CID000019005
Drug	2,6-di-tert-butylpyridine	CP ITGA2	4.72e-05	6	41	2	CID000068510
Drug	AC1L3ZV4	POLI ITGA2	4.72e-05	6	41	2	CID000098142
Drug	AC1MNCFH	CP ITGA2	6.61e-05	7	41	2	CID003301780
Drug	InBr3	POLI ITGA2	6.61e-05	7	41	2	CID000026046
Drug	2,3-diene	POLI ITGA2	8.80e-05	8	41	2	CID000010566
Drug	2 pH	CP ITGA2	8.80e-05	8	41	2	CID000000666
Drug	dibenzalacetone	POLI ITGA2	8.80e-05	8	41	2	CID000095417
Drug	thiazolidinethione	CP ITGA2	1.13e-04	9	41	2	CID002723699
Drug	cadmium	CACNG5 TNFAIP1 CACNA2D2 EARS2 P2RX2 ANXA2	1.32e-04	443	41	6	CID000002514
Drug	manganese carbonyl	POLI ITGA2	1.41e-04	10	41	2	CID000498617
Drug	WIN 54954	ITGA2 VCAN	1.41e-04	10	41	2	CID000441048
Drug	(-)-Quinpirole hydrochloride [85760-74-3]; Up 200; 15.6uM; HL60; HT_HG-U133A	ANXA2 VCAN DNAH17 TFPI	1.64e-04	153	41	4	2977_UP
Drug	borazine	CP ITGA2	1.72e-04	11	41	2	CID006327614
Drug	NSC-312017	POLI ITGA2	1.72e-04	11	41	2	CID000432667
Drug	belinostat	SLIT2 ATP8B1 ITGA2 ANXA2 ANXA2P2 TFPI MYLIP	1.87e-04	678	41	7	ctd:C487081
Disease	hyperthyroidism (biomarker_via_orthology)	CP ANXA2 ANXA2P2	7.96e-06	28	41	3	DOID:7998 (biomarker_via_orthology)
Disease	osteonecrosis (is_implicated_in)	ANXA2 TFPI	8.42e-05	10	41	2	DOID:10159 (is_implicated_in)
Disease	renal cell carcinoma (biomarker_via_orthology)	ANXA2 ANXA2P2	1.70e-04	14	41	2	DOID:4450 (biomarker_via_orthology)
Disease	Tremor, Rubral	CP CACNA2D2	2.23e-04	16	41	2	C0750940
Disease	Ataxia, Appendicular	CP CACNA2D2	2.23e-04	16	41	2	C0750937
Disease	Ataxia, Truncal	CP CACNA2D2	2.23e-04	16	41	2	C0427190
Disease	Ataxia, Motor	CP CACNA2D2	2.23e-04	16	41	2	C0278161
Disease	Abnormal coordination	CP CACNA2D2	2.23e-04	16	41	2	C0520966
Disease	Ataxia, Sensory	CP CACNA2D2	2.23e-04	16	41	2	C0240991
Disease	Epilepsy	CACNA2D2 EARS2 P2RX2	4.72e-04	109	41	3	C0014544
Disease	Ataxia	CP CACNA2D2	5.54e-04	25	41	2	C0004134
Disease	mean reticulocyte volume	POLI ELOVL5 OTUD4 RFC1 IQGAP2 SGPL1	7.75e-04	799	41	6	EFO_0010701
Disease	Endometrioma	ITGA2 VCAN MYLIP	1.46e-03	161	41	3	C0269102
Disease	Endometriosis	ITGA2 VCAN MYLIP	1.46e-03	161	41	3	C0014175
Disease	hippocampal CA1 volume	SLIT2 VCAN	2.04e-03	48	41	2	EFO_0009394
Disease	generalised epilepsy	CACNA2D2 SKAP1	2.39e-03	52	41	2	EFO_0005917

Protein segments in the cluster

Peptide	Gene	Start	Entry
YQSSFQDYNAYQKDK	ACCSL	146	Q4AC99
QNALYSYQKYLESSK	CFAP54	886	Q96N23
SAYQRTYSMKYFKNS	VCAN	3356	P13611
KQTQYYFGSVNASYN	CACNA2D2	1016	Q9NY47
LYNRSNNKYSYTSNS	TNFAIP1	161	Q13829
YYYIQQDTKGDYQKA	ANXA2	316	P07355
FYYLTQNKKSDVYGN	C7orf31	111	Q8N865
YYYIQQDTKGDYQKA	ANXA2P2	316	A6NMY6
KYANNAIKTYKYNAF	ATP8B1	91	O43520
QFYNQTYGSRKYKSD	OTUD4	1041	Q01804
RFNKNNEGTYYSPNY	CP	481	P00450
FTNFYIQTYNKKGAS	ELOVL5	246	Q9NYP7
YLQQESRSKAKYSYF	PER3	706	P56645
TNDKIRNQGYYYSDK	MUC19	891	Q7Z5P9
RNYSQNNSKNYSLKY	CYLC1	266	P35663
YEDKSGKQRYSYQYT	ERGIC1	196	Q969X5
GKQRYSYQYTVANKE	ERGIC1	201	Q969X5
TKFGDYNQNTAKYNY	MYLIP	126	Q8WY64
NTFGAIQYARKYAYS	ITGA2	251	P17301
DIFSKYNSGTYNNQY	PLBD1	341	Q6P4A8
GKSRNYSNSKQKFQY	HFM1	201	A2PYH4
YSNSKQKFQYSANVF	HFM1	206	A2PYH4
SSGYNFRFAKYYKIN	P2RX2	296	Q9UBL9
LNRTKDAETYFNYKY	CACNG5	161	Q9UF02
EYDFSNFYQSKYKRR	CCDC138	31	Q96M89
AFVSYVGYFTKKYRN	DNAH17	3361	Q9UFH2
TGATYQDKRYTNKYS	EIF3D	46	O15371
EKNSKYYNYTLSING	GNS	176	P15586
SSQKDYSYYLDNRLK	POLI	616	Q9UNA4
SLGSYNKYKYNSYRD	SLC6A6	311	P31641
YSNRSAAYAKKGDYQ	STIP1	41	P31948
DSEKKRTNYQAYRSY	RFC1	371	P35251
YNDNRKNKFSDNYYR	TAF2	781	Q6P1X5
NYLSETYQEFRKYFK	IQGAP2	1166	Q13576
TALYNYIFAKKYQGS	EARS2	56	Q5JPH6
YSDKKYRNYQFFVDT	SGPL1	366	O95470
NQKKTYNYYSTLSFT	TMPRSS11E	46	Q9UL52
SKNSSAKNNYGYCSY	VN1R1	196	Q9GZP7
AKNNYGYCSYKASKR	VN1R1	201	Q9GZP7
YEKALKQYNSTGDYR	TSPAN6	126	O43657
YYQKQQGYAACQTTK	SLIT2	1461	O94813
YFYNNQTKQCERFKY	TFPI	141	P10646
SRLFYFSNEKYQKGF	TRAM1	236	Q15629
NYYKCSDYGRAFIQK	ZNF484	326	Q5JVG2
SRGLFYYYANEKSKQ	SKAP1	136	Q86WV1