Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity	PIK3R6 PIK3C2A PIK3CG	1.73e-05	7	160	3	GO:0046934
GeneOntologyMolecularFunction	ATP-dependent activity	MYO7B ABCA12 DYNC2H1 KIF26B CFTR CHD9 CHD2 ATP8B1 DICER1 DNAH17 AFG3L2 MACF1 CHD6 DNAH5 TOP2A TOP2B	3.55e-05	614	160	16	GO:0140657
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex	PIK3R6 PIK3C2A PIK3CG SOCS4	5.83e-05	29	154	4	GO:0005942
GeneOntologyCellularComponent	M band	LRRC39 MYOM3 OBSCN CMYA5	7.63e-05	31	154	4	GO:0031430
GeneOntologyCellularComponent	endosome lumen	APOB RAB38 PTPN2 LRPAP1	2.80e-04	43	154	4	GO:0031904
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex, class IB	PIK3R6 PIK3CG	3.20e-04	4	154	2	GO:0005944
GeneOntologyCellularComponent	A band	LRRC39 MYOM3 OBSCN CMYA5	5.83e-04	52	154	4	GO:0031672
GeneOntologyCellularComponent	dynein complex	DYNC2H1 DISC1 DNAH17 DNAH5	6.73e-04	54	154	4	GO:0030286
Domain	CTF_NFI	NFIB NFIC NFIX	2.02e-06	4	150	3	PF00859
Domain	CTF_NFI_1	NFIB NFIC NFIX	2.02e-06	4	150	3	PS00349
Domain	CTF_NFI_2	NFIB NFIC NFIX	2.02e-06	4	150	3	PS51080
Domain	CTF/NFI_DNA-bd-dom	NFIB NFIC NFIX	2.02e-06	4	150	3	IPR020604
Domain	NfI_DNAbd_pre-N	NFIB NFIC NFIX	2.02e-06	4	150	3	PF10524
Domain	CTF/NFI	NFIB NFIC NFIX	2.02e-06	4	150	3	IPR000647
Domain	CTF/NFI_DNA-bd_N	NFIB NFIC NFIX	2.02e-06	4	150	3	IPR019548
Domain	CTF/NFI_DNA-bd_CS	NFIB NFIC NFIX	2.02e-06	4	150	3	IPR019739
Domain	POU	POU5F2 POU2F1 POU2F2 POU3F4	6.75e-06	16	150	4	SM00352
Domain	POU_dom	POU5F2 POU2F1 POU2F2 POU3F4	6.75e-06	16	150	4	IPR000327
Domain	Pou	POU5F2 POU2F1 POU2F2 POU3F4	6.75e-06	16	150	4	PF00157
Domain	POU_1	POU5F2 POU2F1 POU2F2 POU3F4	6.75e-06	16	150	4	PS00035
Domain	POU_2	POU5F2 POU2F1 POU2F2 POU3F4	6.75e-06	16	150	4	PS00465
Domain	POU_3	POU5F2 POU2F1 POU2F2 POU3F4	6.75e-06	16	150	4	PS51179
Domain	POU	POU5F2 POU2F1 POU2F2 POU3F4	8.77e-06	17	150	4	IPR013847
Domain	P-loop_NTPase	RAB31 MYO7B ABCA12 DYNC2H1 KIF26B CFTR NDST2 MAGI3 CHD9 CHD2 DICER1 RAB38 RND3 SAMD9L SBNO1 AFG3L2 CHD6 COASY DNAH5	5.06e-05	848	150	19	IPR027417
Domain	-	POU5F2 POU2F1 POU2F2 POU3F4	6.07e-05	27	150	4	1.10.260.40
Domain	-	TOP2A TOP2B	6.41e-05	2	150	2	3.40.50.670
Domain	DTHCT	TOP2A TOP2B	6.41e-05	2	150	2	IPR012542
Domain	DNA_gyraseB	TOP2A TOP2B	6.41e-05	2	150	2	PF00204
Domain	-	TOP2A TOP2B	6.41e-05	2	150	2	3.90.199.10
Domain	TopoIIA_CS	TOP2A TOP2B	6.41e-05	2	150	2	IPR018522
Domain	Topo_IIA	TOP2A TOP2B	6.41e-05	2	150	2	IPR001241
Domain	DNA_topoisoIV	TOP2A TOP2B	6.41e-05	2	150	2	PF00521
Domain	K_chnl_volt-dep_Kv2	KCNB2 KCNB1	6.41e-05	2	150	2	IPR003973
Domain	Topo_IIA_A/C_ab	TOP2A TOP2B	6.41e-05	2	150	2	IPR013758
Domain	Topo_IIA_A_a	TOP2A TOP2B	6.41e-05	2	150	2	IPR013757
Domain	Topo_IIA_cen_dom	TOP2A TOP2B	6.41e-05	2	150	2	IPR013759
Domain	TOP4c	TOP2A TOP2B	6.41e-05	2	150	2	SM00434
Domain	TOP2c	TOP2A TOP2B	6.41e-05	2	150	2	SM00433
Domain	Topo_IIA-like_dom	TOP2A TOP2B	6.41e-05	2	150	2	IPR013760
Domain	Topo_IIA_bsu_dom2	TOP2A TOP2B	6.41e-05	2	150	2	IPR013506
Domain	DTHCT	TOP2A TOP2B	6.41e-05	2	150	2	PF08070
Domain	-	TOP2A TOP2B	6.41e-05	2	150	2	1.10.268.10
Domain	TOPRIM_C	TOP2A TOP2B	6.41e-05	2	150	2	IPR031660
Domain	TOPRIM_C	TOP2A TOP2B	6.41e-05	2	150	2	PF16898
Domain	Kv2channel	KCNB2 KCNB1	6.41e-05	2	150	2	PF03521
Domain	Topo_IIA_A/C	TOP2A TOP2B	6.41e-05	2	150	2	IPR002205
Domain	TOPOISOMERASE_II	TOP2A TOP2B	6.41e-05	2	150	2	PS00177
Domain	-	SOX3 SOX5 SOX30 HMGXB4 CCDC124	7.87e-05	55	150	5	1.10.30.10
Domain	Lambda_DNA-bd_dom	POU5F2 POU2F1 POU2F2 POU3F4	8.12e-05	29	150	4	IPR010982
Domain	-	RAB31 MYO7B ABCA12 DYNC2H1 CFTR NDST2 CHD9 CHD2 DICER1 RAB38 RND3 SAMD9L SBNO1 AFG3L2 CHD6 COASY DNAH5	1.05e-04	746	150	17	3.40.50.300
Domain	MAD_homology1_Dwarfin-type	NFIB NFIC NFIX	1.06e-04	12	150	3	IPR003619
Domain	DWA	NFIB NFIC NFIX	1.06e-04	12	150	3	SM00523
Domain	MH1	NFIB NFIC NFIX	1.06e-04	12	150	3	PF03165
Domain	HMG_box_dom	SOX3 SOX5 SOX30 HMGXB4 CCDC124	1.75e-04	65	150	5	IPR009071
Domain	Arg_repress_C-like	TOP2A TOP2B	1.91e-04	3	150	2	IPR024946
Domain	TF_octamer	POU2F1 POU2F2	1.91e-04	3	150	2	IPR000972
Domain	-	TOP2A TOP2B	1.91e-04	3	150	2	3.30.1360.40
Domain	ssDNA-bd_transcriptional_reg	NFIC NFIX	1.91e-04	3	150	2	IPR009044
Domain	Toprim	TOP2A TOP2B	3.80e-04	4	150	2	PF01751
Domain	DUF4200	CFAP100 CCDC42	3.80e-04	4	150	2	IPR025252
Domain	Toprim_domain	TOP2A TOP2B	3.80e-04	4	150	2	IPR006171
Domain	DUF4200	CFAP100 CCDC42	3.80e-04	4	150	2	PF13863
Domain	TOPRIM	TOP2A TOP2B	3.80e-04	4	150	2	PS50880
Domain	ER_TARGET	CALR RCN1 LRPAP1 POGLUT2	5.45e-04	47	150	4	PS00014
Domain	HMG_box	SOX3 SOX5 SOX30 HMGXB4	8.62e-04	53	150	4	PF00505
Domain	Chromo_domain	CHD9 CHD2 CHD6	9.08e-04	24	150	3	IPR023780
Domain	HMG_BOX_2	SOX3 SOX5 SOX30 HMGXB4	9.25e-04	54	150	4	PS50118
Domain	HMG	SOX3 SOX5 SOX30 HMGXB4	9.25e-04	54	150	4	SM00398
Domain	BRK	CHD9 CHD6	9.41e-04	6	150	2	SM00592
Domain	BRK_domain	CHD9 CHD6	9.41e-04	6	150	2	IPR006576
Domain	BRK	CHD9 CHD6	9.41e-04	6	150	2	PF07533
Domain	Chromo	CHD9 CHD2 CHD6	1.15e-03	26	150	3	PF00385
Domain	PI3K_Ras-bd_dom	PIK3C2A PIK3CG	1.31e-03	7	150	2	IPR000341
Domain	PI3K_rbd	PIK3C2A PIK3CG	1.31e-03	7	150	2	SM00144
Domain	PI3K_rbd	PIK3C2A PIK3CG	1.31e-03	7	150	2	PF00794
Domain	PI3K_RBD	PIK3C2A PIK3CG	1.31e-03	7	150	2	PS51546
Domain	CHROMO_1	CHD9 CHD2 CHD6	1.44e-03	28	150	3	PS00598
Domain	CHROMO_2	CHD9 CHD2 CHD6	1.44e-03	28	150	3	PS50013
Domain	DHC_N1	DYNC2H1 DNAH5	1.74e-03	8	150	2	PF08385
Domain	PI3K_C2	PIK3C2A PIK3CG	1.74e-03	8	150	2	SM00142
Domain	PI3K_C2_dom	PIK3C2A PIK3CG	1.74e-03	8	150	2	IPR002420
Domain	PI3K_C2	PIK3C2A PIK3CG	1.74e-03	8	150	2	PF00792
Domain	PI3K_C2	PIK3C2A PIK3CG	1.74e-03	8	150	2	PS51547
Domain	Dynein_heavy_dom-1	DYNC2H1 DNAH5	1.74e-03	8	150	2	IPR013594
Domain	C2_dom	GAK ESYT2 PIK3C2A SYTL4 PIK3CG PLCL1	2.11e-03	164	150	6	IPR000008
Domain	SNF2_N	CHD9 CHD2 CHD6	2.12e-03	32	150	3	IPR000330
Domain	SNF2_N	CHD9 CHD2 CHD6	2.12e-03	32	150	3	PF00176
Domain	Chromodomain-like	CHD9 CHD2 CHD6	2.12e-03	32	150	3	IPR016197
Domain	PI3Ka	PIK3C2A PIK3CG	2.22e-03	9	150	2	PF00613
Domain	PI3Ka	PIK3C2A PIK3CG	2.22e-03	9	150	2	SM00145
Domain	-	PIK3C2A PIK3CG	2.22e-03	9	150	2	1.25.40.70
Domain	EF-hand-dom_pair	EFCAB5 RCN1 TPCN1 LPCAT2 ANKEF1 MACF1 PLCL1 DMD	2.26e-03	287	150	8	IPR011992
Domain	Chromo/shadow_dom	CHD9 CHD2 CHD6	2.32e-03	33	150	3	IPR000953
Domain	CHROMO	CHD9 CHD2 CHD6	2.32e-03	33	150	3	SM00298
Domain	PI_Kinase	PIK3C2A PIK3CG	2.76e-03	10	150	2	IPR015433
Domain	PInositide-3_kin_accessory_dom	PIK3C2A PIK3CG	2.76e-03	10	150	2	IPR001263
Domain	PIK_HELICAL	PIK3C2A PIK3CG	2.76e-03	10	150	2	PS51545
Domain	Kinase-like_dom	GAK OBSCN CHD9 SRPK1 CHEK1 PIK3C2A PIK3CG PRKAA1 FER MACF1 DMD	4.40e-03	542	150	11	IPR011009
Domain	-	EFCAB5 RCN1 LPCAT2 ANKEF1 MACF1 PLCL1 DMD	5.20e-03	261	150	7	1.10.238.10
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH5	5.47e-03	14	150	2	IPR024317
Domain	Dynein_HC_stalk	DYNC2H1 DNAH5	5.47e-03	14	150	2	IPR024743
Domain	Dynein_heavy_dom-2	DYNC2H1 DNAH5	5.47e-03	14	150	2	IPR013602
Domain	DHC_N2	DYNC2H1 DNAH5	5.47e-03	14	150	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DYNC2H1 DNAH5	5.47e-03	14	150	2	IPR011704
Domain	MT	DYNC2H1 DNAH5	5.47e-03	14	150	2	PF12777
Domain	AAA_8	DYNC2H1 DNAH5	5.47e-03	14	150	2	PF12780
Domain	AAA_5	DYNC2H1 DNAH5	5.47e-03	14	150	2	PF07728
Domain	AAA	ABCA12 DYNC2H1 CFTR AFG3L2 DNAH5	6.16e-03	144	150	5	SM00382
Pathway	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION	POU2F1 GTF3C4 NFIB NFIC NFIX	1.73e-05	41	112	5	M739
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CASP8AP2 GAK DYNC2H1 CALR DNAJC25 UBR4 RCN1 SRPK1 TIMMDC1 ANKLE2 PRPF40A DICER1 NBAS PTPN2 ESYT2 SUGT1 PIK3C2A RAB3GAP2 AFG3L2 MACF1 LRPAP1 COASY DDHD2 SLC30A9 ZNF512 ESPL1 ANKRD52 DEPDC1B TOP2B	1.25e-10	1487	167	29	33957083
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	CASP8AP2 KDM5B ZNF609 UBR4 ATG2B CKAP5 C15orf39 ZDBF2 CHEK1 BRMS1L GTF3C4 RAB3GAP2 CHD6 ANKRD52 CNOT1 TANGO6	2.27e-10	418	167	16	34709266
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	KDM5B DISC1 CFTR POU2F1 CHD2 RO60 ATP8B1 CMYA5 IGSF10 SAMD9L PIK3C2A RAB3GAP2 PAH CEP41 AEBP2 DDHD2 TET3	4.05e-08	686	167	17	29987050
Pubmed	Tagging genes with cassette-exchange sites.	NPL KDM5B UBR4 ANKLE2 PRPF40A PHKB SBNO1 NFIB SOCS4 MACF1 AFDN ANKRD52	9.06e-08	335	167	12	15741177
Pubmed	NFI-B3, a novel transcriptional repressor of the nuclear factor I family, is generated by alternative RNA processing.	NFIB NFIC NFIX	1.09e-07	3	167	3	9099724
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	EFCAB5 MYO7B SRPK1 PRPF40A MACF1 DMD DNAH5 SLC4A5 TOP2A TOP2B	2.20e-07	234	167	10	36243803
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	UBR4 ATG2B ZDBF2 CHEK1 BRMS1L TIMMDC1 ANKLE2 NBAS PTPN2 ESYT2 SUGT1 PIK3C2A RAB3GAP2 AFG3L2 PUS1 ALDH4A1 MPHOSPH10 GEMIN6 DDHD2 SLC30A9 ZNF512 ESPL1 DEPDC1B TOP2A	2.29e-07	1496	167	24	32877691
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	GAK CALR UBR4 SPCS2 CKAP5 RCN1 SRPK1 CHEK1 DICER1 PTPN2 ESYT2 PRKAA1 AFG3L2 PUS1 AFDN C3 DMD ESPL1 ANKRD52	2.59e-07	974	167	19	28675297
Pubmed	Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development.	NFIB NFIC NFIX	4.33e-07	4	167	3	9056636
Pubmed	Nuclear factor one transcription factors as epigenetic regulators in cancer.	NFIB NFIC NFIX	4.33e-07	4	167	3	28076901
Pubmed	Transcription factor NF 1 expression in involuting mammary gland.	NFIB NFIC NFIX	4.33e-07	4	167	3	10959417
Pubmed	Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH.	NFIB NFIC NFIX	4.33e-07	4	167	3	7590749
Pubmed	RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin.	NFIB NFIC NFIX	4.33e-07	4	167	3	12624117
Pubmed	Altered expression of the developmentally regulated NFI gene family during phorbol ester-induced differentiation of human leukemic cells.	NFIB NFIC NFIX	4.33e-07	4	167	3	9052991
Pubmed	Genomic organization, splice products and mouse chromosomal localization of genes for transcription factor Nuclear Factor One.	NFIB NFIC NFIX	4.33e-07	4	167	3	12568726
Pubmed	Regulation of the CYP3A4 and CYP3A7 promoters by members of the nuclear factor I transcription factor family.	NFIB NFIC NFIX	1.08e-06	5	167	3	19706729
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ZNF609 CALR SPCS2 CKAP5 FGFRL1 CHD2 PRPF40A GTF3C4 ESYT2 AFG3L2 LRPAP1 RNF216 AFDN TAF2 SLC30A9 ZNF512 CNOT1 THAP12 TOP2A TOP2B	1.49e-06	1203	167	20	29180619
Pubmed	Temporal control of a dendritogenesis-linked gene via REST-dependent regulation of nuclear factor I occupancy.	NFIB NFIC NFIX	2.15e-06	6	167	3	21270437
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	ZNF609 CKAP5 DICER1 LPCAT2 PIK3C2A SYTL4 PRKAA1 FER MACF1 MPHOSPH10 TAF2 ZNF512 ESPL1 CNOT1 TOP2B	2.45e-06	724	167	15	36232890
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	CALR SPCS2 RCN1 ANKLE2 NBAS PTPN2 OSBP ESYT2 LPCAT2 RAB3GAP2 LRPAP1 SLC30A9	3.06e-06	468	167	12	31056421
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	CALR UBR4 CKAP5 SRPK1 RPS19 CHD2 PRPF40A DICER1 MACF1 AFDN MPHOSPH10 ZNF512 ANKRD52 CNOT1	3.63e-06	653	167	14	22586326
Pubmed	NFI in the development of the olfactory neuroepithelium and the regulation of olfactory marker protein gene expression.	NFIB NFIC NFIX	3.75e-06	7	167	3	10762365
Pubmed	TGF-β/NF1/Smad4-mediated suppression of ANT2 contributes to oxidative stress in cellular senescence.	NFIB NFIC NFIX	3.75e-06	7	167	3	25220407
Pubmed	Sequence requirements of the FFAT-like motif for specific binding to VAP-A are revealed by NMR.	KCNB2 OSBP KCNB1	3.75e-06	7	167	3	34312846
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	GAK SPCS2 ATG2B CKAP5 ZDBF2 ANKLE2 NBAS PTPN2 ESYT2 CCDC124 SUGT1 LPCAT2 RAB3GAP2	4.06e-06	568	167	13	37774976
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	CASP8AP2 SPCS2 CKAP5 RCN1 RPS19 CHEK1 DICER1 CCDC124 SUGT1 SLC22A8 SYTL4 NFIB NFIC NFIX ANKEF1 C3 PLCL1 HSD17B2 ZNF512 ESPL1	4.39e-06	1293	167	20	15342556
Pubmed	Expansion of the lateral ventricles and ependymal deficits underlie the hydrocephalus evident in mice lacking the transcription factor NFIX.	SOX3 NFIB NFIX	5.98e-06	8	167	3	25960350
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	KIF26B ATG2B ZDBF2 DICER1 ESYT2 CCDC124 MACF1 DDHD2	8.31e-06	209	167	8	36779422
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	CALR HMGXB4 POU2F1 CHD9 CHD2 GTF3C4 SBNO1 NFIC CHD6 TAF2 ZNF512 TOP2A TOP2B	8.42e-06	608	167	13	36089195
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ATG2B CKAP5 MAGI3 RPS19 ANKLE2 PRPF40A ESYT2 CCDC124 RAB3GAP2 AFG3L2 MACF1 AFDN CNOT1 DEPDC1B	9.08e-06	708	167	14	39231216
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ZNF609 OBSCN LAMA3 PORCN FGFRL1 MAGI3 CHD9 CHD2 ATP8B1 PHKB ESYT2 NFIB NFIC NFIX SBF2 MACF1 CHD6 ZNF512 TET3 CNOT1 SLC4A5	1.02e-05	1489	167	21	28611215
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	UBR4 CKAP5 SRPK1 ESYT2 AFG3L2 CNOT1 TOP2A TOP2B	1.25e-05	221	167	8	29991511
Pubmed	Mapping of multiple mouse loci related to the farnesyl pyrophosphate synthetase gene.	APOB C3 ALDH4A1	1.27e-05	10	167	3	8499655
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	KIF26B DISC1 UBR4 MYOM3 OBSCN CKAP5 MAGI3 RPS19 CHD2 QRICH2 IGSF10 SAMD9L CHD6 CNOT1	1.40e-05	736	167	14	29676528
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	WDR64 DYNC2H1 UBR4 CHD2 ZDBF2 OSBP NFIB CHD6 MPHOSPH10 TAF2 ZNF512 ANKRD52 CNOT1	1.40e-05	638	167	13	31182584
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	CKAP5 RPS19 ANKLE2 NBAS PTPN2 ESYT2 LPCAT2 AFDN SLC30A9 CNOT1	1.49e-05	375	167	10	32788342
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	CASP8AP2 ZNF609 HMGXB4 SPCS2 CKAP5 RPS19 CHD2 BRMS1L PRPF40A GTF3C4 ESYT2 NFIB NFIC NFIX AFG3L2 CHD6 TET3 TOP2A TOP2B	1.60e-05	1294	167	19	30804502
Pubmed	NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance.	NPL KDM5B TOP2A TOP2B	1.66e-05	32	167	4	38060382
Pubmed	Nfix regulates fetal-specific transcription in developing skeletal muscle.	NFIB NFIC NFIX	1.74e-05	11	167	3	20178747
Pubmed	Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study.	CFTR KCNB2 ZC3H12C	1.74e-05	11	167	3	17903301
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DYNC2H1 CALR UBR4 CKAP5 RPS19 APOB RO60 CMYA5 PRPF40A DICER1 SBNO1 RAB3GAP2 PUS1 AFDN COASY ZNF512 DNAH5 CNOT1 TOP2A TOP2B	1.81e-05	1425	167	20	30948266
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	KDM5B CHD2 BRMS1L GTF3C4 AFG3L2 AEBP2 CHD6 TAF2 CNOT1 TOP2A TOP2B	1.83e-05	469	167	11	27634302
Pubmed	DNA topoisomerase II is dispensable for oocyte meiotic resumption but is essential for meiotic chromosome condensation and separation in mice.	TOP2A TOP2B	2.29e-05	2	167	2	24048577
Pubmed	MicroRNAs are indispensable for reprogramming mouse embryonic fibroblasts into induced stem cell-like cells.	KIF26B DICER1	2.29e-05	2	167	2	22737231
Pubmed	Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction.	KCNB2 KCNB1	2.29e-05	2	167	2	28607108
Pubmed	Use of divalent metal ions in the dna cleavage reaction of human type II topoisomerases.	TOP2A TOP2B	2.29e-05	2	167	2	19222228
Pubmed	Parental attitudes regarding newborn screening of PKU and DMD.	PAH DMD	2.29e-05	2	167	2	12833401
Pubmed	Human Oct-1L isoform has tissue-specific expression pattern similar to Oct-2.	POU2F1 POU2F2	2.29e-05	2	167	2	12663137
Pubmed	Evidence for a mutant allele of the gene for DNA topoisomerase II in adriamycin-resistant P388 murine leukemia cells.	TOP2A TOP2B	2.29e-05	2	167	2	2555055
Pubmed	Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation.	TOP2A TOP2B	2.29e-05	2	167	2	1331984
Pubmed	Doxorubicin-induced cardiotoxicity is maturation dependent due to the shift from topoisomerase IIα to IIβ in human stem cell derived cardiomyocytes.	TOP2A TOP2B	2.29e-05	2	167	2	31106979
Pubmed	A biochemical analysis of topoisomerase II alpha and beta kinase activity found in HIV-1 infected cells and virus.	TOP2A TOP2B	2.29e-05	2	167	2	16091284
Pubmed	Kv2 Ion Channels Determine the Expression and Localization of the Associated AMIGO-1 Cell Adhesion Molecule in Adult Brain Neurons.	KCNB2 KCNB1	2.29e-05	2	167	2	29403353
Pubmed	Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis.	PIK3R6 PIK3CG	2.29e-05	2	167	2	21996737
Pubmed	PI3Kgamma adaptor subunits define coupling to degranulation and cell motility by distinct PtdIns(3,4,5)P3 pools in mast cells.	PIK3R6 PIK3CG	2.29e-05	2	167	2	19509406
Pubmed	Calreticulin negatively regulates the cell surface expression of cystic fibrosis transmembrane conductance regulator.	CALR CFTR	2.29e-05	2	167	2	16527813
Pubmed	Interaction of newly synthesized apolipoprotein B with calnexin and calreticulin requires glucose trimming in the endoplasmic reticulum.	CALR APOB	2.29e-05	2	167	2	10513896
Pubmed	Mining topoisomerase isoforms in gastric cancer.	TOP2A TOP2B	2.29e-05	2	167	2	32535049
Pubmed	Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development.	TOP2A TOP2B	2.29e-05	2	167	2	1380833
Pubmed	Functional interaction of Oct transcription factors with the family of repeats in Epstein-Barr virus oriP.	POU2F1 POU2F2	2.29e-05	2	167	2	15831936
Pubmed	Differential dimer activities of the transcription factor Oct-1 by DNA-induced interface swapping.	POU2F1 POU2F2	2.29e-05	2	167	2	11583619
Pubmed	Inhibition of cystic fibrosis transmembrane conductance regulator by novel interaction with the metabolic sensor AMP-activated protein kinase.	CFTR PRKAA1	2.29e-05	2	167	2	10862786
Pubmed	Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake.	POU2F1 POU2F2	2.29e-05	2	167	2	31771949
Pubmed	The phospholipid flippase ATP8B1 mediates apical localization of the cystic fibrosis transmembrane regulator.	CFTR ATP8B1	2.29e-05	2	167	2	27301931
Pubmed	Remodeling neuronal ER-PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels.	KCNB2 KCNB1	2.29e-05	2	167	2	30091655
Pubmed	Involvement of human topoisomerase II isoforms in HIV-1 reverse transcription.	TOP2A TOP2B	2.29e-05	2	167	2	23399433
Pubmed	Enhanced processing of UVA-irradiated DNA by human topoisomerase II in living cells.	TOP2A TOP2B	2.29e-05	2	167	2	15044480
Pubmed	C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo.	TOP2A TOP2B	2.29e-05	2	167	2	17526531
Pubmed	Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.	RRM2B TNNT3	2.29e-05	2	167	2	29596868
Pubmed	DNA topoisomerase II distribution in mouse preimplantation embryos.	TOP2A TOP2B	2.29e-05	2	167	2	11835579
Pubmed	Identification of novel single-stranded DNA binding proteins recognizing octamer motif.	POU2F1 POU2F2	2.29e-05	2	167	2	8185580
Pubmed	Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes.	TOP2A TOP2B	2.29e-05	2	167	2	2556712
Pubmed	CHD6 regulates the topological arrangement of the CFTR locus.	CFTR CHD6	2.29e-05	2	167	2	25631877
Pubmed	Using a biochemical approach to identify the primary dimerization regions in human DNA topoisomerase IIalpha.	TOP2A TOP2B	2.29e-05	2	167	2	10473615
Pubmed	Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain.	TOP2A TOP2B	2.29e-05	2	167	2	9224616
Pubmed	DNA damage response during chromatin remodeling in elongating spermatids of mice.	TOP2A TOP2B	2.29e-05	2	167	2	18032420
Pubmed	Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants.	TOP2A TOP2B	2.29e-05	2	167	2	22111588
Pubmed	Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.	TOP2A TOP2B	2.29e-05	2	167	2	17578914
Pubmed	Disrupted interaction between CFTR and AF-6/afadin aggravates malignant phenotypes of colon cancer.	CFTR AFDN	2.29e-05	2	167	2	24373847
Pubmed	Topoisomerase II alpha and topoisomerase II beta genes: characterization and mapping to human chromosomes 17 and 3, respectively.	TOP2A TOP2B	2.29e-05	2	167	2	1309226
Pubmed	3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase the binding activity and nuclear level of Oct-1 in mononuclear cells.	POU2F1 POU2F2	2.29e-05	2	167	2	12144930
Pubmed	Interplay between myofibers and pro-inflammatory macrophages controls muscle damage in mdx mice.	PRKAA1 DMD	2.29e-05	2	167	2	34471933
Pubmed	Kinetic analysis of human topoisomerase IIalpha and beta DNA binding by surface plasmon resonance.	TOP2A TOP2B	2.29e-05	2	167	2	14596941
Pubmed	Enhanced expression of DNA topoisomerase II genes in human medulloblastoma and its possible association with etoposide sensitivity.	TOP2A TOP2B	2.29e-05	2	167	2	17361331
Pubmed	Molecular cloning and characterization of the human topoisomerase IIalpha and IIbeta genes: evidence for isoform evolution through gene duplication.	TOP2A TOP2B	2.29e-05	2	167	2	10095062
Pubmed	Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.	TOP2A TOP2B	2.29e-05	2	167	2	14996935
Pubmed	p84 forms a negative regulatory complex with p110γ to control PI3Kγ signalling during cell migration.	PIK3R6 PIK3CG	2.29e-05	2	167	2	25753393
Pubmed	Structural organization of the human TOP2A and TOP2B genes.	TOP2A TOP2B	2.29e-05	2	167	2	9795238
Pubmed	The distribution of DNA topoisomerase II isoforms in differentiated adult mouse tissues.	TOP2A TOP2B	2.29e-05	2	167	2	8241259
Pubmed	Phosphatidylinositol 3-kinase regulates the CD4/CD8 T cell differentiation ratio.	PIK3R6 PIK3CG	2.29e-05	2	167	2	12707323
Pubmed	Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cells.	TOP2A TOP2B	2.29e-05	2	167	2	11927602
Pubmed	Topoisomerase II binds importin alpha isoforms and exportin/CRM1 but does not shuttle between the nucleus and cytoplasm in proliferating cells.	TOP2A TOP2B	2.29e-05	2	167	2	17182034
Pubmed	Genetic enhancement of behavioral itch responses in mice lacking phosphoinositide 3-kinase-γ (PI3Kγ).	PIK3R6 PIK3CG	2.29e-05	2	167	2	22168443
Pubmed	Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs).	PIK3R6 PIK3CG	2.29e-05	2	167	2	24190998
Pubmed	Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons.	TOP2A TOP2B	2.29e-05	2	167	2	28700616
Pubmed	Predictors and mechanisms of epilepsy occurrence in cerebral gliomas: What to look for in clinicopathology.	TOP2A TOP2B	2.29e-05	2	167	2	28087392
Pubmed	Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint.	TOP2A TOP2B	2.29e-05	2	167	2	28472494
Pubmed	Transcriptional diversity during lineage commitment of human blood progenitors.	NFIB NFIC	2.29e-05	2	167	2	25258084
Pubmed	Association of immunophenotype with expression of topoisomerase II α and β in adult acute myeloid leukemia.	TOP2A TOP2B	2.29e-05	2	167	2	32218491
Pubmed	Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules.	POU2F1 POU2F2	2.29e-05	2	167	2	8156594
Interaction	FEV interactions	SOX5 ZNF609 C15orf39 POU2F1 BRMS1L NFIB NFIC CHD6 TAF2 ZNF512	4.46e-06	203	157	10	int:FEV
Interaction	SYNE3 interactions	GAK CALR DNAJC25 RCN1 ANKLE2 PRPF40A NBAS ESYT2 CCDC66 PIK3C2A MACF1 LRPAP1 POGLUT2 CNOT1	1.03e-05	444	157	14	int:SYNE3
Interaction	BCAP31 interactions	CALR DNAJC25 CFTR SPCS2 APOB KCNB2 TIMMDC1 ANKLE2 NBAS PTPN2 OSBP ESYT2 LPCAT2 LRPAP1 SLC30A9	2.95e-05	554	157	15	int:BCAP31
Interaction	SOX6 interactions	SOX5 ZNF609 C15orf39 POU2F1 BRMS1L NFIB NFIC NFIX	3.25e-05	157	157	8	int:SOX6
Interaction	DDA1 interactions	ABCA12 RRM2B POU2F1 GTF3C4 PTPN2 SBNO1 NFIC NFIX PRKAA1 MPHOSPH10 TAF2 CRTC2	3.26e-05	368	157	12	int:DDA1
Interaction	RCOR1 interactions	SOX5 CASP8AP2 KDM5B UBR4 ATG2B CKAP5 C15orf39 ZDBF2 BRMS1L NFIB RAB3GAP2 CHD6 ANKRD52 TANGO6	3.35e-05	494	157	14	int:RCOR1
Interaction	WNT6 interactions	SPCS2 PORCN CHEK1	3.76e-05	9	157	3	int:WNT6
Interaction	SOX2 interactions	SOX3 SOX5 KDM5B ZNF609 NT5E CALR UBR4 CKAP5 RCN1 LAMA3 POU2F1 CHD9 SRPK1 RPS19 ZDBF2 BRMS1L ESYT2 NFIB NFIC NFIX MACF1 C3 CHD6 TAF2 ZNF512 CNOT1	3.92e-05	1422	157	26	int:SOX2
Interaction	SOX5 interactions	SOX5 ZNF609 POU2F1 BRMS1L NFIB NFIC NFIX CHD6	4.06e-05	162	157	8	int:SOX5
Interaction	PAX2 interactions	ZNF609 POU2F1 BRMS1L NFIB NFIC NFIX	5.35e-05	85	157	6	int:PAX2
Interaction	PAX7 interactions	ZNF609 POU2F1 BRMS1L NFIB NFIC NFIX CHD6	5.35e-05	124	157	7	int:PAX7
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	SPDYE17 SPDYE10 CCDC146 SPDYE9 SPDYE12 SPDYE11 SPDYE13 SPDYE15 SPDYE8 SPDYE14	7.62e-08	271	169	10	chr7q11
Cytoband	7q11.23	SPDYE10 CCDC146 SPDYE9 SPDYE8 SPDYE14	3.12e-05	97	169	5	7q11.23
GeneFamily	POU class homeoboxes and pseudogenes	POU5F2 POU2F1 POU2F2 POU3F4	8.74e-06	23	105	4	523
GeneFamily	SRY-boxes	SOX3 SOX5 SOX30	1.72e-04	19	105	3	757
GeneFamily	Topoisomerases	TOP2A TOP2B	4.94e-04	6	105	2	1050
GeneFamily	Phosphatidylinositol 3-kinase subunits	PIK3C2A PIK3CG	9.14e-04	8	105	2	831
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE9 SPDYE8	2.12e-03	12	105	2	756
Coexpression	GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN	ASB16-AS1 LRRC39 CHD9 SRPK1 PHKB NBAS RAB3GAP2 CEP41 ZNF512	4.00e-06	197	162	9	M8271
Coexpression	YAGI_AML_WITH_T_8_21_TRANSLOCATION	CALR RCN1 POU2F2 APOB ANKLE2 PRPF40A NBAS OSBP NFIX MACF1 ESPL1	2.15e-05	372	162	11	M19261
Coexpression	GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_6H_UP	KDM5B ABCA12 CFTR APOB SBNO1 NFIB C3 MPHOSPH10	3.25e-05	197	162	8	M8159
Coexpression	GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_DN	ARSK POU2F2 CHD9 PIK3CG AEBP2 AFDN CD302 PXYLP1	3.62e-05	200	162	8	M8486
Coexpression	GSE3203_UNTREATED_VS_IFNB_TREATED_LN_BCELL_UP	MAGI3 ZDBF2 TPCN1 PHKB PIK3CG PRKAA1 TAF2 SLC30A9	3.62e-05	200	162	8	M6795
Coexpression	GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	RAB31 RRM2B POU2F2 CHD9 CHD2 PIK3C2A RNF216 PLCL1	3.62e-05	200	162	8	M9161
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	KIF26B CKAP5 BRMS1L PRPF40A CCDC66 SLC22A8 NFIB NFIX CHD6 TOP2B	1.45e-05	246	156	10	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	GAK ARSK DYNC2H1 CKAP5 POU2F1 CHD9 CHD2 PRPF40A PTPN2 CCDC66 SUGT1 NFIX CEP41 MACF1 PXYLP1 DMD	1.66e-05	629	156	16	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	SOX5 CASP8AP2 KIF26B CKAP5 POU2F1 POU3F4 CHD2 ZDBF2 BRMS1L PRPF40A CCDC66 EML5 SLC22A8 NFIB NFIX CHD6 ZC3H12C MPHOSPH10 DMD TOP2B	3.61e-05	983	156	20	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CKAP5 CHD9 CMYA5 IGSF10 FER MACF1 DMD TOP2B	3.04e-07	176	164	8	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B ABCA12 KIF26B CFTR OBSCN APOB DMD DNAH5	4.26e-07	184	164	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B ABCA12 KIF26B CFTR OBSCN APOB DMD DNAH5	4.26e-07	184	164	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B ABCA12 KIF26B CFTR OBSCN APOB DMD DNAH5	4.26e-07	184	164	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	KDM5B CKAP5 POU2F1 RO60 GTF3C4 PIK3C2A SBF2 CD302	6.11e-07	193	164	8	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	POU3F4 ATP8B1 BRMS1L ANKLE2 CYP39A1 TPCN1 RAB38 GEMIN6	6.87e-07	196	164	8	7be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC1 CCDC146 DYNC2H1 CFAP100 WDR93 KCNB1 DMD DNAH5	7.14e-07	197	164	8	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-OPC_related-Oligodendrocyte/OPC\|2m / Sample Type, Dataset, Time_group, and Cell type.	RCN1 POU2F1 RPS19 EDIL3 RND3 NFIB NFIX ZC3H12C	8.00e-07	200	164	8	3c9a2f02294a9fb892b89e856291bd6423ffa0a9
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-OPC_related\|2m / Sample Type, Dataset, Time_group, and Cell type.	RCN1 POU2F1 RPS19 EDIL3 RND3 NFIB NFIX ZC3H12C	8.00e-07	200	164	8	8e49e7e9b02d8411e4ffae1f5113a2c18f5bf179
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-OPC_related\|10w / Sample Type, Dataset, Time_group, and Cell type.	SOX3 RCN1 RPS19 RND3 NFIB PAH AFDN ZC3H12C	8.00e-07	200	164	8	8f5d98f962ddd8c4658c89ff8a2894de1228562a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-OPC_related-Oligodendrocyte/OPC\|10w / Sample Type, Dataset, Time_group, and Cell type.	SOX3 RCN1 RPS19 RND3 NFIB PAH AFDN ZC3H12C	8.00e-07	200	164	8	345f1eac498cc87fd7bf08e7312608b2d6fe1dd7
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD13B SOX5 C15orf39 TFB1M FER POGLUT2 ESPL1	3.04e-06	168	164	7	b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RCN1 DICER1 GTF3C4 PTPN2 MPHOSPH10 TAF2 CRTC2	3.28e-06	170	164	7	0f215911b5880eeffeb43230f7eeaf55b612eaf2
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LPCAT2 CCDC42 ZC3H12C ESPL1 TNNT3 DEPDC1B TOP2A	3.41e-06	171	164	7	4ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL C15orf39 POU2F2 LPCAT2 PIK3CG SOCS4 PRKAA1	4.13e-06	176	164	7	d687e6c3f9043f2574d072f815b8c2258f9dc7b5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL C15orf39 POU2F2 LPCAT2 PIK3CG SOCS4 PRKAA1	4.13e-06	176	164	7	4f37854124d77ee64dcb40fd491eaed2ba389891
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL C15orf39 POU2F2 LPCAT2 PIK3CG SOCS4 PRKAA1	4.13e-06	176	164	7	0afba8707b847e5bdf6f38fe4379967631fe2240
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL MYO7B APOB SLC16A12 SLC22A8 PAH DNAH5	4.28e-06	177	164	7	9c7c6824b9011363851f084a500d665f025b026e
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL MYO7B APOB SLC16A12 SLC22A8 PAH DNAH5	4.28e-06	177	164	7	2bf639e9e801e5144462ffc957f5739e0dfcd500
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPL MYO7B MYOM3 SLC16A12 SLC22A8 NFIB PAH	6.59e-06	189	164	7	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPL MYO7B MYOM3 SLC16A12 SLC22A8 NFIB PAH	6.59e-06	189	164	7	13fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAB31 DISC1 POU2F2 CD1E PIK3R6 DHRS9 C3	7.55e-06	193	164	7	3e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAB31 DISC1 POU2F2 CD1E PIK3R6 DHRS9 TRAF3IP3	8.35e-06	196	164	7	291c59b609985167c98a40d4e2caeea2fad74941
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAB31 DISC1 POU2F2 CD1E PIK3R6 DHRS9 TRAF3IP3	8.63e-06	197	164	7	826cc6baafab13e7ef5cfcf28cd79d0fbf3af38d
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	SOX5 ZNF609 MAGI3 NBAS SBF2 FER DMD	9.22e-06	199	164	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DYNC2H1 KIF26B IGSF10 RND3 SYTL4 MACF1 CD302	9.53e-06	200	164	7	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal\|6m / Sample Type, Dataset, Time_group, and Cell type.	LRRC39 CCDC146 MYOM3 ISM2 HSD17B2 TNNT3 SLC4A5	9.53e-06	200	164	7	13ec8afea86e4a10599c924871ba4e325b0a8013
ToppCell	droplet-Thymus-nan-21m-Myeloid-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POU2F2 CYP39A1 KCNB1 LPCAT2 DNAH17 TNNT3	3.75e-05	168	164	6	69dd747be46e7fbcec571cddd6dee374b9c2507a
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NT5E KIF26B CHRNA5 ZNF594 C3 DEPDC1B	3.75e-05	168	164	6	de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC1 CCDC146 DYNC2H1 CFAP100 WDR93 DNAH5	3.88e-05	169	164	6	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LRRC39 POU5F2 LAMA3 POU3F4 SLC6A1 RND3	4.14e-05	171	164	6	a5634b76476b8b2488a706bbab5141f7bd94631f
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CHEK1 QRICH2 IGSF10 NFIB ESPL1 TOP2A	4.71e-05	175	164	6	a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC1 CCDC146 DYNC2H1 DHRS9 CEP41 DNAH5	4.86e-05	176	164	6	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 KIF26B EDIL3 ESYT2 FER PXYLP1	5.51e-05	180	164	6	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC1 DYNC2H1 CFAP100 WDR93 AFDN DNAH5	5.51e-05	180	164	6	92fb01b91261b3103454924cde56add337b41844
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	MYOM3 OBSCN CMYA5 RNF216 PXYLP1 DMD	5.86e-05	182	164	6	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD9 RPS19 CHD2 SAMD9L MACF1 TOP2B	5.86e-05	182	164	6	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	CCDC146 DYNC2H1 CFAP100 WDR93 DNAH5 SPATA4	5.86e-05	182	164	6	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	6.04e-05	183	164	6	b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|367C / Donor, Lineage, Cell class and subclass (all cells)	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	6.04e-05	183	164	6	cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL APOB SLC16A12 SLC22A8 PAH ALDH4A1	6.22e-05	184	164	6	c86ed59fed687cdaaf7e9c4418d2e3e2c4111cca
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL APOB SLC16A12 SLC22A8 PAH ALDH4A1	6.22e-05	184	164	6	7c256bcfa07c5ff55aad0833e8712b0456b5832b
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL APOB SLC16A12 SLC22A8 PAH ALDH4A1	6.22e-05	184	164	6	3d7dd193a0826cc7a4e454a29236a16c315e5965
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL APOB SLC16A12 SLC22A8 PAH ALDH4A1	6.22e-05	184	164	6	45577ff91c3b2b303acd97239dde2463ea7a429c
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL APOB SLC16A12 SLC22A8 PAH ALDH4A1	6.41e-05	185	164	6	3e3217c99719fd1d2fa94e16be7712a7e5077152
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL APOB SLC16A12 SLC22A8 PAH ALDH4A1	6.41e-05	185	164	6	0ff4148b4701003d9d594e0da8261176fb13aa59
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	DCDC1 CCDC146 DYNC2H1 CFAP100 WDR93 DNAH5	6.41e-05	185	164	6	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPL MYO7B SLC16A12 TPCN1 SLC22A8 PAH	6.80e-05	187	164	6	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPL MYO7B SLC16A12 TPCN1 SLC22A8 PAH	6.80e-05	187	164	6	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	(09)_Ionocytes-(4)_1wkpi\|(09)_Ionocytes / shred by cell type and Timepoint	LRPAP1 RNF216 C3	6.96e-05	22	164	3	b35fb230042a027b10ef3e7ef09bf13ea1cdc506
ToppCell	Control-CD4+_T_activated\|Control / Disease condition and Cell class	SOX5 ISM2 CD1E SAMD9L DNAH5	7.01e-05	116	164	5	e3d1a90a229f5697b2b715574bb96790a435f73b
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS19 CHD2 PRPF40A SBNO1 NFIB AEBP2	7.01e-05	188	164	6	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	15-Distal-RBC\|Distal / Age, Tissue, Lineage and Cell class	NPL APOB RHD SLC6A1 PAH HSD17B2	7.01e-05	188	164	6	c68ccb1c5c21d13ddac09b16e7d466f0530bbda5
ToppCell	15-Distal-RBC-RBC\|Distal / Age, Tissue, Lineage and Cell class	NPL APOB RHD SLC6A1 PAH HSD17B2	7.01e-05	188	164	6	2534684e4932c1255c24a26ca2277ac7af0a118b
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	KDM5B DISC1 DUS1L NBAS SOCS4 LRRC37B	7.22e-05	189	164	6	99b01893da9f9f7c9528afaffad178285211738b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DCDC1 MYO7B MYOM3 KCNB2 NFIB PAH	7.22e-05	189	164	6	28b502611829e4a24caff2562545c7db97686099
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	NT5E CFTR SLC6A1 PLCL1 HSD17B2 DNAH5	7.43e-05	190	164	6	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	LRRC39 MYOM3 OBSCN CMYA5 PLCL1 DMD	7.43e-05	190	164	6	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 CMYA5 NFIB FER AFDN PXYLP1	7.65e-05	191	164	6	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	LRRC39 MYOM3 OBSCN CMYA5 PLCL1 DMD	7.65e-05	191	164	6	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD9 RND3 NFIB NFIX C3 CD302	7.65e-05	191	164	6	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD9 EDIL3 IGSF10 NFIX C3 CD302	7.87e-05	192	164	6	11088878043a6ff95ba1970361256a82e434b80a
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	MYOM3 OBSCN CMYA5 RNF216 PLCL1 DMD	8.10e-05	193	164	6	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DCDC1 DYNC2H1 CFAP100 IGSF10 NFIX DNAH5	8.10e-05	193	164	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DCDC1 CCDC146 DYNC2H1 CFAP100 DMD DNAH5	8.10e-05	193	164	6	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DCDC1 DYNC2H1 CFAP100 WDR93 DNAH5 SPATA4	8.33e-05	194	164	6	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RCN1 NFIB NFIC NFIX C3 CD302	8.33e-05	194	164	6	9709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CASP8AP2 RCN1 IGSF10 RND3 NFIB TOP2A	8.33e-05	194	164	6	af4bbb2deb5a3913eb58990690fc3c62fbc3708c
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RCN1 NFIB NFIC NFIX C3 CD302	8.33e-05	194	164	6	93b7a9065430740ec31fce4e8c14ffccb498591d
ToppCell	facs-GAT-Fat-18m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RCN1 NFIB NFIC NFIX C3 CD302	8.33e-05	194	164	6	0d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCell	(1)_Dll4_loss-of-function\|World / Stress and Cell class	POU2F2 SRPK1 RPS19 RAB38 TRAF3IP3 TOP2A	8.57e-05	195	164	6	def4b2350e08a36ffddca71ea80ef611f2d437d9
ToppCell	(1)_Dll4_loss-of-function-(0)_LMPP_(LSK_cells)\|World / Stress and Cell class	POU2F2 SRPK1 RPS19 RAB38 TRAF3IP3 TOP2A	8.57e-05	195	164	6	f11cf4b6855a26ff6ea572eebaad2aad6bb2434b
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IGSF10 NFIB NFIC NFIX C3 CD302	8.57e-05	195	164	6	773728703bc8969bff0e1de58fe3e1631add0a0a
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD9 CMYA5 IGSF10 RND3 NFIX CD302	8.57e-05	195	164	6	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 RND3 NFIB C3 DMD DNAH5	8.82e-05	196	164	6	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 RND3 NFIB C3 DMD DNAH5	8.82e-05	196	164	6	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	hematopoetic_progenitors-CD34+_HSC\|hematopoetic_progenitors / Lineage and Cell class	RPS19 IGSF10 CCDC42 SYTL4 NFIB AFDN	8.82e-05	196	164	6	d3e20212c15cff0a3c4e23e8b94715b5822a43e2
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NT5E IGSF10 NFIB MACF1 AFDN DMD	8.82e-05	196	164	6	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NT5E IGSF10 NFIB MACF1 AFDN DMD	8.82e-05	196	164	6	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	DYNC2H1 LAMA3 CHD9 IGSF10 SAMD9L CD302	9.06e-05	197	164	6	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DYNC2H1 IGSF10 RND3 SYTL4 MACF1 CD302	9.06e-05	197	164	6	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	Bronchial_Brush-Epithelial\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	CCDC146 DYNC2H1 RND3 NFIB DHRS9 DNAH5	9.06e-05	197	164	6	272c7f4e582ef57564450540242b0db766b78328
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-Treg\|ICU-SEP / Disease, condition lineage and cell class	EFCAB5 OBSCN ZDBF2 PLCL1 TRAF3IP3 POGLUT2	9.06e-05	197	164	6	c3ee2d522fbfe67069ddba2d1abfc4f5ca230c26
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-G\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	SLC16A12 IGSF10 MACF1 LRPAP1 CD302 HSD17B2	9.06e-05	197	164	6	a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCell	Epithelial_cells-Epithelial_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	MYOM3 SLC16A12 SLC22A8 NFIB PAH ALDH4A1	9.32e-05	198	164	6	52e9d41a1726bc1140df6baec9f17a534448ac8b
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	CCDC146 CFAP100 DHRS9 C3 HSD17B2 DNAH5	9.32e-05	198	164	6	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	moderate-Epithelial-Secretory\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RCN1 MAGI3 RND3 NFIB DHRS9 C3	9.32e-05	198	164	6	7d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	CCDC146 CFAP100 DHRS9 C3 HSD17B2 DNAH5	9.32e-05	198	164	6	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	Epithelial_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	MYOM3 SLC16A12 SLC22A8 NFIB PAH ALDH4A1	9.32e-05	198	164	6	eeec789d226171f30799577cc37c07bdced2e3cb
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DYNC2H1 IGSF10 RND3 SYTL4 MACF1 CD302	9.58e-05	199	164	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	distal-1-Epithelial-Ciliated\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	9.58e-05	199	164	6	4120e4a2bc05adebe1e1e9670ed7ea55142eb83d
ToppCell	distal-3-Epithelial-Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	9.58e-05	199	164	6	7e5f29f4ec1fea92f2c0064eea151d2d474ef904
ToppCell	distal-Epithelial-Ciliated-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	9.58e-05	199	164	6	6ce0df4a6f4d9353919e26ffab97c9ec89911da6
ToppCell	Caecum-Dendritic_cell\|Caecum / Region, Cell class and subclass	RAB31 RND3 CD1E LPCAT2 CD302 TOP2A	9.85e-05	200	164	6	b91d3d7505a022ca360ab5b3f9955753d111f974
ToppCell	mLN-Mast_cell-Mast\|mLN / Region, Cell class and subclass	NDST2 PIK3R6 KCNB1 LPCAT2 DHRS9 ALDH4A1	9.85e-05	200	164	6	81ea6e7a3940277751faf9097b30198159998c7b
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	LAMA3 MAGI3 EML5 AFDN C3 ALDH4A1	9.85e-05	200	164	6	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	Caecum-Dendritic_cell-cycling_DCs\|Caecum / Region, Cell class and subclass	RND3 CD1E LPCAT2 CD302 DEPDC1B TOP2A	9.85e-05	200	164	6	608be9bfe74f8d3202aa92b2905452a06f340f76
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	9.85e-05	200	164	6	5abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCell	mLN-Mast_cell\|mLN / Region, Cell class and subclass	NDST2 PIK3R6 KCNB1 LPCAT2 DHRS9 ALDH4A1	9.85e-05	200	164	6	9a5f1d99d8d160923d4d0fbbf9ad48a26f8a4fad
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	9.85e-05	200	164	6	9c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
Drug	7-biopterin	NFIB NFIC NFIX PAH	1.60e-06	13	160	4	CID005488923
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD2 CHD6	5.00e-06	7	156	3	DOID:0050834 (implicated_via_orthology)
Disease	B cell deficiency (implicated_via_orthology)	TOP2A TOP2B	2.78e-05	2	156	2	DOID:2115 (implicated_via_orthology)
Disease	immune system disease (implicated_via_orthology)	POU2F1 POU2F2	8.30e-05	3	156	2	DOID:2914 (implicated_via_orthology)
Disease	Myoclonic-astatic epilepsy	CHD2 SLC6A1	8.30e-05	3	156	2	cv:C0393702
Disease	Autism Spectrum Disorders	SOX5 CHD2 PAH CEP41 TET3	9.04e-05	85	156	5	C1510586
Disease	esophageal adenocarcinoma, Barrett's esophagus	CFTR APOB PLCL1	5.84e-04	31	156	3	EFO_0000280, EFO_0000478
Disease	Malignant neoplasm of breast	DYNC2H1 UBR4 OBSCN POU2F1 ATP8B1 CHEK1 RHD PHKB SBNO1 ANKEF1 PRKAA1 PUS1 MACF1 DMD TOP2A	5.98e-04	1074	156	15	C0006142
Disease	lung cancer (is_implicated_in)	CALR SOX30 CFTR CHRNA5	6.49e-04	74	156	4	DOID:1324 (is_implicated_in)
Disease	Deafness, Sensorineural, Autosomal-Mitochondrial Type	POU3F4 TFB1M	7.62e-04	8	156	2	C1857332
Disease	memory impairment	PRPF40A LRRC37B	7.62e-04	8	156	2	EFO_0001072
Disease	membranous glomerulonephritis (implicated_via_orthology)	LRPAP1 C3	9.76e-04	9	156	2	DOID:10976 (implicated_via_orthology)
Disease	autism spectrum disorder (implicated_via_orthology)	KDM5B NDST2 CHD9 CHD2 CHD6	1.31e-03	152	156	5	DOID:0060041 (implicated_via_orthology)
Disease	Colorectal Carcinoma	ABCA12 CALR CFTR OBSCN RCN1 APOB KCNB2 RAB38 OSBP TRAF3IP3 DMD	1.32e-03	702	156	11	C0009402
Disease	virologic response measurement, response to abacavir	IGSF10 PIK3C2A FER	1.43e-03	42	156	3	EFO_0006905, EFO_0006906
Disease	Macrocephaly	NFIB TET3	1.48e-03	11	156	2	C0221355
Disease	alpha angle measurement	SOX5 TFB1M	1.48e-03	11	156	2	EFO_0020071
Disease	Myoclonic Astatic Epilepsy	CHD2 SLC6A1	1.48e-03	11	156	2	C0393702
Disease	Oligospermia	DICER1 TPCN1	1.77e-03	12	156	2	C0028960
Disease	acute myeloid leukemia (implicated_via_orthology)	TOP2A TOP2B	1.77e-03	12	156	2	DOID:9119 (implicated_via_orthology)
Disease	Myeloproliferative disease	CALR ATG2B	1.77e-03	12	156	2	C0027022
Disease	mortality	SOX5 GAK EDIL3 DICER1 DMD	2.31e-03	173	156	5	EFO_0004352
Disease	Schizophrenia	SOX5 DISC1 CHEK1 CMYA5 DICER1 CHRNA5 RHD SLC6A1 EML5 KCNB1 SBNO1 PAH	2.64e-03	883	156	12	C0036341
Disease	Intellectual Disability	DISC1 RRM2B NFIB PUS1 MACF1 ALDH4A1 TAF2 TET3	2.69e-03	447	156	8	C3714756
Disease	Ciliopathies	DYNC2H1 CFTR CEP41 DNAH5	2.81e-03	110	156	4	C4277690
Disease	sickle cell anemia (is_implicated_in)	APOB C3	3.17e-03	16	156	2	DOID:10923 (is_implicated_in)
Disease	ankle brachial index	NBAS DMD	3.17e-03	16	156	2	EFO_0003912
Disease	response to statin	SOX5 DISC1 APOB	3.27e-03	56	156	3	GO_0036273
Disease	alpha-L-iduronidase measurement	GAK FGFRL1	3.59e-03	17	156	2	EFO_0020139
Disease	Familial Progressive Myoclonic Epilepsy	CHD2 AFG3L2	3.59e-03	17	156	2	C0751777
Disease	Atypical Inclusion-Body Disease	CHD2 AFG3L2	3.59e-03	17	156	2	C0751776
Disease	Myoclonic Epilepsies, Progressive	CHD2 AFG3L2	3.59e-03	17	156	2	C0751778
Disease	Biotin-Responsive Encephalopathy	CHD2 AFG3L2	3.59e-03	17	156	2	C0751780
Disease	May-White Syndrome	CHD2 AFG3L2	3.59e-03	17	156	2	C0751782
Disease	Dentatorubral-Pallidoluysian Atrophy	CHD2 AFG3L2	3.59e-03	17	156	2	C0751781
Disease	ankle injury	CHD9 NFIB TAF2	3.79e-03	59	156	3	EFO_1002021
Disease	diet measurement	SOX5 KIF26B C16orf78 POU2F2 CHD2 APOB RND3 NBAS NFIX CHD6 DNAH5 CNOT1 CRTC2	3.89e-03	1049	156	13	EFO_0008111
Disease	Myeloid Leukemia	ATG2B TOP2B	4.02e-03	18	156	2	C0023470
Disease	Leukemia, Monocytic, Chronic	ATG2B TOP2B	4.02e-03	18	156	2	C0023466
Disease	Action Myoclonus-Renal Failure Syndrome	CHD2 AFG3L2	4.02e-03	18	156	2	C0751779
Disease	loneliness measurement	EDIL3 SLC6A1 MACF1 PLCL1	4.32e-03	124	156	4	EFO_0007865
Disease	response to methotrexate, neurotoxicity	MACF1 PLCL1	4.48e-03	19	156	2	EFO_0011057, GO_0031427
Disease	unipolar depression	SOX5 CASP8AP2 DCDC1 POU5F2 DYNC2H1 DISC1 C16orf78 BRMS1L NBAS KCNB1 FER CHD6 DMD SLC30A9	4.91e-03	1206	156	14	EFO_0003761
Disease	PR interval	EFCAB5 ABCA12 OBSCN FER MACF1 CHD6 CNOT1 THAP12	4.97e-03	495	156	8	EFO_0004462
Disease	blood lead measurement	PTPN2 KCNB1 SPESP1	5.20e-03	66	156	3	EFO_0007040
GeneOntologyMolecularFunction	1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity	PIK3R6 PIK3C2A PIK3CG	1.73e-05	7	160	3	GO:0046934
GeneOntologyMolecularFunction	ATP-dependent activity	MYO7B ABCA12 DYNC2H1 KIF26B CFTR CHD9 CHD2 ATP8B1 DICER1 DNAH17 AFG3L2 MACF1 CHD6 DNAH5 TOP2A TOP2B	3.55e-05	614	160	16	GO:0140657
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex	PIK3R6 PIK3C2A PIK3CG SOCS4	5.83e-05	29	154	4	GO:0005942
GeneOntologyCellularComponent	M band	LRRC39 MYOM3 OBSCN CMYA5	7.63e-05	31	154	4	GO:0031430
GeneOntologyCellularComponent	endosome lumen	APOB RAB38 PTPN2 LRPAP1	2.80e-04	43	154	4	GO:0031904
GeneOntologyCellularComponent	phosphatidylinositol 3-kinase complex, class IB	PIK3R6 PIK3CG	3.20e-04	4	154	2	GO:0005944
GeneOntologyCellularComponent	A band	LRRC39 MYOM3 OBSCN CMYA5	5.83e-04	52	154	4	GO:0031672
GeneOntologyCellularComponent	dynein complex	DYNC2H1 DISC1 DNAH17 DNAH5	6.73e-04	54	154	4	GO:0030286
Domain	CTF_NFI	NFIB NFIC NFIX	2.02e-06	4	150	3	PF00859
Domain	CTF_NFI_1	NFIB NFIC NFIX	2.02e-06	4	150	3	PS00349
Domain	CTF_NFI_2	NFIB NFIC NFIX	2.02e-06	4	150	3	PS51080
Domain	CTF/NFI_DNA-bd-dom	NFIB NFIC NFIX	2.02e-06	4	150	3	IPR020604
Domain	NfI_DNAbd_pre-N	NFIB NFIC NFIX	2.02e-06	4	150	3	PF10524
Domain	CTF/NFI	NFIB NFIC NFIX	2.02e-06	4	150	3	IPR000647
Domain	CTF/NFI_DNA-bd_N	NFIB NFIC NFIX	2.02e-06	4	150	3	IPR019548
Domain	CTF/NFI_DNA-bd_CS	NFIB NFIC NFIX	2.02e-06	4	150	3	IPR019739
Domain	POU	POU5F2 POU2F1 POU2F2 POU3F4	6.75e-06	16	150	4	SM00352
Domain	POU_dom	POU5F2 POU2F1 POU2F2 POU3F4	6.75e-06	16	150	4	IPR000327
Domain	Pou	POU5F2 POU2F1 POU2F2 POU3F4	6.75e-06	16	150	4	PF00157
Domain	POU_1	POU5F2 POU2F1 POU2F2 POU3F4	6.75e-06	16	150	4	PS00035
Domain	POU_2	POU5F2 POU2F1 POU2F2 POU3F4	6.75e-06	16	150	4	PS00465
Domain	POU_3	POU5F2 POU2F1 POU2F2 POU3F4	6.75e-06	16	150	4	PS51179
Domain	POU	POU5F2 POU2F1 POU2F2 POU3F4	8.77e-06	17	150	4	IPR013847
Domain	P-loop_NTPase	RAB31 MYO7B ABCA12 DYNC2H1 KIF26B CFTR NDST2 MAGI3 CHD9 CHD2 DICER1 RAB38 RND3 SAMD9L SBNO1 AFG3L2 CHD6 COASY DNAH5	5.06e-05	848	150	19	IPR027417
Domain	-	POU5F2 POU2F1 POU2F2 POU3F4	6.07e-05	27	150	4	1.10.260.40
Domain	-	TOP2A TOP2B	6.41e-05	2	150	2	3.40.50.670
Domain	DTHCT	TOP2A TOP2B	6.41e-05	2	150	2	IPR012542
Domain	DNA_gyraseB	TOP2A TOP2B	6.41e-05	2	150	2	PF00204
Domain	-	TOP2A TOP2B	6.41e-05	2	150	2	3.90.199.10
Domain	TopoIIA_CS	TOP2A TOP2B	6.41e-05	2	150	2	IPR018522
Domain	Topo_IIA	TOP2A TOP2B	6.41e-05	2	150	2	IPR001241
Domain	DNA_topoisoIV	TOP2A TOP2B	6.41e-05	2	150	2	PF00521
Domain	K_chnl_volt-dep_Kv2	KCNB2 KCNB1	6.41e-05	2	150	2	IPR003973
Domain	Topo_IIA_A/C_ab	TOP2A TOP2B	6.41e-05	2	150	2	IPR013758
Domain	Topo_IIA_A_a	TOP2A TOP2B	6.41e-05	2	150	2	IPR013757
Domain	Topo_IIA_cen_dom	TOP2A TOP2B	6.41e-05	2	150	2	IPR013759
Domain	TOP4c	TOP2A TOP2B	6.41e-05	2	150	2	SM00434
Domain	TOP2c	TOP2A TOP2B	6.41e-05	2	150	2	SM00433
Domain	Topo_IIA-like_dom	TOP2A TOP2B	6.41e-05	2	150	2	IPR013760
Domain	Topo_IIA_bsu_dom2	TOP2A TOP2B	6.41e-05	2	150	2	IPR013506
Domain	DTHCT	TOP2A TOP2B	6.41e-05	2	150	2	PF08070
Domain	-	TOP2A TOP2B	6.41e-05	2	150	2	1.10.268.10
Domain	TOPRIM_C	TOP2A TOP2B	6.41e-05	2	150	2	IPR031660
Domain	TOPRIM_C	TOP2A TOP2B	6.41e-05	2	150	2	PF16898
Domain	Kv2channel	KCNB2 KCNB1	6.41e-05	2	150	2	PF03521
Domain	Topo_IIA_A/C	TOP2A TOP2B	6.41e-05	2	150	2	IPR002205
Domain	TOPOISOMERASE_II	TOP2A TOP2B	6.41e-05	2	150	2	PS00177
Domain	-	SOX3 SOX5 SOX30 HMGXB4 CCDC124	7.87e-05	55	150	5	1.10.30.10
Domain	Lambda_DNA-bd_dom	POU5F2 POU2F1 POU2F2 POU3F4	8.12e-05	29	150	4	IPR010982
Domain	-	RAB31 MYO7B ABCA12 DYNC2H1 CFTR NDST2 CHD9 CHD2 DICER1 RAB38 RND3 SAMD9L SBNO1 AFG3L2 CHD6 COASY DNAH5	1.05e-04	746	150	17	3.40.50.300
Domain	MAD_homology1_Dwarfin-type	NFIB NFIC NFIX	1.06e-04	12	150	3	IPR003619
Domain	DWA	NFIB NFIC NFIX	1.06e-04	12	150	3	SM00523
Domain	MH1	NFIB NFIC NFIX	1.06e-04	12	150	3	PF03165
Domain	HMG_box_dom	SOX3 SOX5 SOX30 HMGXB4 CCDC124	1.75e-04	65	150	5	IPR009071
Domain	Arg_repress_C-like	TOP2A TOP2B	1.91e-04	3	150	2	IPR024946
Domain	TF_octamer	POU2F1 POU2F2	1.91e-04	3	150	2	IPR000972
Domain	-	TOP2A TOP2B	1.91e-04	3	150	2	3.30.1360.40
Domain	ssDNA-bd_transcriptional_reg	NFIC NFIX	1.91e-04	3	150	2	IPR009044
Domain	Toprim	TOP2A TOP2B	3.80e-04	4	150	2	PF01751
Domain	DUF4200	CFAP100 CCDC42	3.80e-04	4	150	2	IPR025252
Domain	Toprim_domain	TOP2A TOP2B	3.80e-04	4	150	2	IPR006171
Domain	DUF4200	CFAP100 CCDC42	3.80e-04	4	150	2	PF13863
Domain	TOPRIM	TOP2A TOP2B	3.80e-04	4	150	2	PS50880
Domain	ER_TARGET	CALR RCN1 LRPAP1 POGLUT2	5.45e-04	47	150	4	PS00014
Domain	HMG_box	SOX3 SOX5 SOX30 HMGXB4	8.62e-04	53	150	4	PF00505
Domain	Chromo_domain	CHD9 CHD2 CHD6	9.08e-04	24	150	3	IPR023780
Domain	HMG_BOX_2	SOX3 SOX5 SOX30 HMGXB4	9.25e-04	54	150	4	PS50118
Domain	HMG	SOX3 SOX5 SOX30 HMGXB4	9.25e-04	54	150	4	SM00398
Domain	BRK	CHD9 CHD6	9.41e-04	6	150	2	SM00592
Domain	BRK_domain	CHD9 CHD6	9.41e-04	6	150	2	IPR006576
Domain	BRK	CHD9 CHD6	9.41e-04	6	150	2	PF07533
Domain	Chromo	CHD9 CHD2 CHD6	1.15e-03	26	150	3	PF00385
Domain	PI3K_Ras-bd_dom	PIK3C2A PIK3CG	1.31e-03	7	150	2	IPR000341
Domain	PI3K_rbd	PIK3C2A PIK3CG	1.31e-03	7	150	2	SM00144
Domain	PI3K_rbd	PIK3C2A PIK3CG	1.31e-03	7	150	2	PF00794
Domain	PI3K_RBD	PIK3C2A PIK3CG	1.31e-03	7	150	2	PS51546
Domain	CHROMO_1	CHD9 CHD2 CHD6	1.44e-03	28	150	3	PS00598
Domain	CHROMO_2	CHD9 CHD2 CHD6	1.44e-03	28	150	3	PS50013
Domain	DHC_N1	DYNC2H1 DNAH5	1.74e-03	8	150	2	PF08385
Domain	PI3K_C2	PIK3C2A PIK3CG	1.74e-03	8	150	2	SM00142
Domain	PI3K_C2_dom	PIK3C2A PIK3CG	1.74e-03	8	150	2	IPR002420
Domain	PI3K_C2	PIK3C2A PIK3CG	1.74e-03	8	150	2	PF00792
Domain	PI3K_C2	PIK3C2A PIK3CG	1.74e-03	8	150	2	PS51547
Domain	Dynein_heavy_dom-1	DYNC2H1 DNAH5	1.74e-03	8	150	2	IPR013594
Domain	C2_dom	GAK ESYT2 PIK3C2A SYTL4 PIK3CG PLCL1	2.11e-03	164	150	6	IPR000008
Domain	SNF2_N	CHD9 CHD2 CHD6	2.12e-03	32	150	3	IPR000330
Domain	SNF2_N	CHD9 CHD2 CHD6	2.12e-03	32	150	3	PF00176
Domain	Chromodomain-like	CHD9 CHD2 CHD6	2.12e-03	32	150	3	IPR016197
Domain	PI3Ka	PIK3C2A PIK3CG	2.22e-03	9	150	2	PF00613
Domain	PI3Ka	PIK3C2A PIK3CG	2.22e-03	9	150	2	SM00145
Domain	-	PIK3C2A PIK3CG	2.22e-03	9	150	2	1.25.40.70
Domain	EF-hand-dom_pair	EFCAB5 RCN1 TPCN1 LPCAT2 ANKEF1 MACF1 PLCL1 DMD	2.26e-03	287	150	8	IPR011992
Domain	Chromo/shadow_dom	CHD9 CHD2 CHD6	2.32e-03	33	150	3	IPR000953
Domain	CHROMO	CHD9 CHD2 CHD6	2.32e-03	33	150	3	SM00298
Domain	PI_Kinase	PIK3C2A PIK3CG	2.76e-03	10	150	2	IPR015433
Domain	PInositide-3_kin_accessory_dom	PIK3C2A PIK3CG	2.76e-03	10	150	2	IPR001263
Domain	PIK_HELICAL	PIK3C2A PIK3CG	2.76e-03	10	150	2	PS51545
Domain	Kinase-like_dom	GAK OBSCN CHD9 SRPK1 CHEK1 PIK3C2A PIK3CG PRKAA1 FER MACF1 DMD	4.40e-03	542	150	11	IPR011009
Domain	-	EFCAB5 RCN1 LPCAT2 ANKEF1 MACF1 PLCL1 DMD	5.20e-03	261	150	7	1.10.238.10
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH5	5.47e-03	14	150	2	IPR024317
Domain	Dynein_HC_stalk	DYNC2H1 DNAH5	5.47e-03	14	150	2	IPR024743
Domain	Dynein_heavy_dom-2	DYNC2H1 DNAH5	5.47e-03	14	150	2	IPR013602
Domain	DHC_N2	DYNC2H1 DNAH5	5.47e-03	14	150	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DYNC2H1 DNAH5	5.47e-03	14	150	2	IPR011704
Domain	MT	DYNC2H1 DNAH5	5.47e-03	14	150	2	PF12777
Domain	AAA_8	DYNC2H1 DNAH5	5.47e-03	14	150	2	PF12780
Domain	AAA_5	DYNC2H1 DNAH5	5.47e-03	14	150	2	PF07728
Domain	AAA	ABCA12 DYNC2H1 CFTR AFG3L2 DNAH5	6.16e-03	144	150	5	SM00382
Pathway	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION	POU2F1 GTF3C4 NFIB NFIC NFIX	1.73e-05	41	112	5	M739
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CASP8AP2 GAK DYNC2H1 CALR DNAJC25 UBR4 RCN1 SRPK1 TIMMDC1 ANKLE2 PRPF40A DICER1 NBAS PTPN2 ESYT2 SUGT1 PIK3C2A RAB3GAP2 AFG3L2 MACF1 LRPAP1 COASY DDHD2 SLC30A9 ZNF512 ESPL1 ANKRD52 DEPDC1B TOP2B	1.25e-10	1487	167	29	33957083
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	CASP8AP2 KDM5B ZNF609 UBR4 ATG2B CKAP5 C15orf39 ZDBF2 CHEK1 BRMS1L GTF3C4 RAB3GAP2 CHD6 ANKRD52 CNOT1 TANGO6	2.27e-10	418	167	16	34709266
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	KDM5B DISC1 CFTR POU2F1 CHD2 RO60 ATP8B1 CMYA5 IGSF10 SAMD9L PIK3C2A RAB3GAP2 PAH CEP41 AEBP2 DDHD2 TET3	4.05e-08	686	167	17	29987050
Pubmed	Tagging genes with cassette-exchange sites.	NPL KDM5B UBR4 ANKLE2 PRPF40A PHKB SBNO1 NFIB SOCS4 MACF1 AFDN ANKRD52	9.06e-08	335	167	12	15741177
Pubmed	NFI-B3, a novel transcriptional repressor of the nuclear factor I family, is generated by alternative RNA processing.	NFIB NFIC NFIX	1.09e-07	3	167	3	9099724
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	EFCAB5 MYO7B SRPK1 PRPF40A MACF1 DMD DNAH5 SLC4A5 TOP2A TOP2B	2.20e-07	234	167	10	36243803
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	UBR4 ATG2B ZDBF2 CHEK1 BRMS1L TIMMDC1 ANKLE2 NBAS PTPN2 ESYT2 SUGT1 PIK3C2A RAB3GAP2 AFG3L2 PUS1 ALDH4A1 MPHOSPH10 GEMIN6 DDHD2 SLC30A9 ZNF512 ESPL1 DEPDC1B TOP2A	2.29e-07	1496	167	24	32877691
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	GAK CALR UBR4 SPCS2 CKAP5 RCN1 SRPK1 CHEK1 DICER1 PTPN2 ESYT2 PRKAA1 AFG3L2 PUS1 AFDN C3 DMD ESPL1 ANKRD52	2.59e-07	974	167	19	28675297
Pubmed	Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development.	NFIB NFIC NFIX	4.33e-07	4	167	3	9056636
Pubmed	Nuclear factor one transcription factors as epigenetic regulators in cancer.	NFIB NFIC NFIX	4.33e-07	4	167	3	28076901
Pubmed	Transcription factor NF 1 expression in involuting mammary gland.	NFIB NFIC NFIX	4.33e-07	4	167	3	10959417
Pubmed	Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH.	NFIB NFIC NFIX	4.33e-07	4	167	3	7590749
Pubmed	RFX1 and NF-1 associate with P sequences of the human growth hormone locus in pituitary chromatin.	NFIB NFIC NFIX	4.33e-07	4	167	3	12624117
Pubmed	Altered expression of the developmentally regulated NFI gene family during phorbol ester-induced differentiation of human leukemic cells.	NFIB NFIC NFIX	4.33e-07	4	167	3	9052991
Pubmed	Genomic organization, splice products and mouse chromosomal localization of genes for transcription factor Nuclear Factor One.	NFIB NFIC NFIX	4.33e-07	4	167	3	12568726
Pubmed	Regulation of the CYP3A4 and CYP3A7 promoters by members of the nuclear factor I transcription factor family.	NFIB NFIC NFIX	1.08e-06	5	167	3	19706729
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ZNF609 CALR SPCS2 CKAP5 FGFRL1 CHD2 PRPF40A GTF3C4 ESYT2 AFG3L2 LRPAP1 RNF216 AFDN TAF2 SLC30A9 ZNF512 CNOT1 THAP12 TOP2A TOP2B	1.49e-06	1203	167	20	29180619
Pubmed	Temporal control of a dendritogenesis-linked gene via REST-dependent regulation of nuclear factor I occupancy.	NFIB NFIC NFIX	2.15e-06	6	167	3	21270437
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	ZNF609 CKAP5 DICER1 LPCAT2 PIK3C2A SYTL4 PRKAA1 FER MACF1 MPHOSPH10 TAF2 ZNF512 ESPL1 CNOT1 TOP2B	2.45e-06	724	167	15	36232890
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	CALR SPCS2 RCN1 ANKLE2 NBAS PTPN2 OSBP ESYT2 LPCAT2 RAB3GAP2 LRPAP1 SLC30A9	3.06e-06	468	167	12	31056421
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	CALR UBR4 CKAP5 SRPK1 RPS19 CHD2 PRPF40A DICER1 MACF1 AFDN MPHOSPH10 ZNF512 ANKRD52 CNOT1	3.63e-06	653	167	14	22586326
Pubmed	NFI in the development of the olfactory neuroepithelium and the regulation of olfactory marker protein gene expression.	NFIB NFIC NFIX	3.75e-06	7	167	3	10762365
Pubmed	TGF-β/NF1/Smad4-mediated suppression of ANT2 contributes to oxidative stress in cellular senescence.	NFIB NFIC NFIX	3.75e-06	7	167	3	25220407
Pubmed	Sequence requirements of the FFAT-like motif for specific binding to VAP-A are revealed by NMR.	KCNB2 OSBP KCNB1	3.75e-06	7	167	3	34312846
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	GAK SPCS2 ATG2B CKAP5 ZDBF2 ANKLE2 NBAS PTPN2 ESYT2 CCDC124 SUGT1 LPCAT2 RAB3GAP2	4.06e-06	568	167	13	37774976
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	CASP8AP2 SPCS2 CKAP5 RCN1 RPS19 CHEK1 DICER1 CCDC124 SUGT1 SLC22A8 SYTL4 NFIB NFIC NFIX ANKEF1 C3 PLCL1 HSD17B2 ZNF512 ESPL1	4.39e-06	1293	167	20	15342556
Pubmed	Expansion of the lateral ventricles and ependymal deficits underlie the hydrocephalus evident in mice lacking the transcription factor NFIX.	SOX3 NFIB NFIX	5.98e-06	8	167	3	25960350
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	KIF26B ATG2B ZDBF2 DICER1 ESYT2 CCDC124 MACF1 DDHD2	8.31e-06	209	167	8	36779422
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	CALR HMGXB4 POU2F1 CHD9 CHD2 GTF3C4 SBNO1 NFIC CHD6 TAF2 ZNF512 TOP2A TOP2B	8.42e-06	608	167	13	36089195
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	ATG2B CKAP5 MAGI3 RPS19 ANKLE2 PRPF40A ESYT2 CCDC124 RAB3GAP2 AFG3L2 MACF1 AFDN CNOT1 DEPDC1B	9.08e-06	708	167	14	39231216
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ZNF609 OBSCN LAMA3 PORCN FGFRL1 MAGI3 CHD9 CHD2 ATP8B1 PHKB ESYT2 NFIB NFIC NFIX SBF2 MACF1 CHD6 ZNF512 TET3 CNOT1 SLC4A5	1.02e-05	1489	167	21	28611215
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	UBR4 CKAP5 SRPK1 ESYT2 AFG3L2 CNOT1 TOP2A TOP2B	1.25e-05	221	167	8	29991511
Pubmed	Mapping of multiple mouse loci related to the farnesyl pyrophosphate synthetase gene.	APOB C3 ALDH4A1	1.27e-05	10	167	3	8499655
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	KIF26B DISC1 UBR4 MYOM3 OBSCN CKAP5 MAGI3 RPS19 CHD2 QRICH2 IGSF10 SAMD9L CHD6 CNOT1	1.40e-05	736	167	14	29676528
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	WDR64 DYNC2H1 UBR4 CHD2 ZDBF2 OSBP NFIB CHD6 MPHOSPH10 TAF2 ZNF512 ANKRD52 CNOT1	1.40e-05	638	167	13	31182584
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	CKAP5 RPS19 ANKLE2 NBAS PTPN2 ESYT2 LPCAT2 AFDN SLC30A9 CNOT1	1.49e-05	375	167	10	32788342
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	CASP8AP2 ZNF609 HMGXB4 SPCS2 CKAP5 RPS19 CHD2 BRMS1L PRPF40A GTF3C4 ESYT2 NFIB NFIC NFIX AFG3L2 CHD6 TET3 TOP2A TOP2B	1.60e-05	1294	167	19	30804502
Pubmed	NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance.	NPL KDM5B TOP2A TOP2B	1.66e-05	32	167	4	38060382
Pubmed	Nfix regulates fetal-specific transcription in developing skeletal muscle.	NFIB NFIC NFIX	1.74e-05	11	167	3	20178747
Pubmed	Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study.	CFTR KCNB2 ZC3H12C	1.74e-05	11	167	3	17903301
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DYNC2H1 CALR UBR4 CKAP5 RPS19 APOB RO60 CMYA5 PRPF40A DICER1 SBNO1 RAB3GAP2 PUS1 AFDN COASY ZNF512 DNAH5 CNOT1 TOP2A TOP2B	1.81e-05	1425	167	20	30948266
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	KDM5B CHD2 BRMS1L GTF3C4 AFG3L2 AEBP2 CHD6 TAF2 CNOT1 TOP2A TOP2B	1.83e-05	469	167	11	27634302
Pubmed	DNA topoisomerase II is dispensable for oocyte meiotic resumption but is essential for meiotic chromosome condensation and separation in mice.	TOP2A TOP2B	2.29e-05	2	167	2	24048577
Pubmed	MicroRNAs are indispensable for reprogramming mouse embryonic fibroblasts into induced stem cell-like cells.	KIF26B DICER1	2.29e-05	2	167	2	22737231
Pubmed	Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction.	KCNB2 KCNB1	2.29e-05	2	167	2	28607108
Pubmed	Use of divalent metal ions in the dna cleavage reaction of human type II topoisomerases.	TOP2A TOP2B	2.29e-05	2	167	2	19222228
Pubmed	Parental attitudes regarding newborn screening of PKU and DMD.	PAH DMD	2.29e-05	2	167	2	12833401
Pubmed	Human Oct-1L isoform has tissue-specific expression pattern similar to Oct-2.	POU2F1 POU2F2	2.29e-05	2	167	2	12663137
Pubmed	Evidence for a mutant allele of the gene for DNA topoisomerase II in adriamycin-resistant P388 murine leukemia cells.	TOP2A TOP2B	2.29e-05	2	167	2	2555055
Pubmed	Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation.	TOP2A TOP2B	2.29e-05	2	167	2	1331984
Pubmed	Doxorubicin-induced cardiotoxicity is maturation dependent due to the shift from topoisomerase IIα to IIβ in human stem cell derived cardiomyocytes.	TOP2A TOP2B	2.29e-05	2	167	2	31106979
Pubmed	A biochemical analysis of topoisomerase II alpha and beta kinase activity found in HIV-1 infected cells and virus.	TOP2A TOP2B	2.29e-05	2	167	2	16091284
Pubmed	Kv2 Ion Channels Determine the Expression and Localization of the Associated AMIGO-1 Cell Adhesion Molecule in Adult Brain Neurons.	KCNB2 KCNB1	2.29e-05	2	167	2	29403353
Pubmed	Differential roles for the p101 and p84 regulatory subunits of PI3Kγ in tumor growth and metastasis.	PIK3R6 PIK3CG	2.29e-05	2	167	2	21996737
Pubmed	PI3Kgamma adaptor subunits define coupling to degranulation and cell motility by distinct PtdIns(3,4,5)P3 pools in mast cells.	PIK3R6 PIK3CG	2.29e-05	2	167	2	19509406
Pubmed	Calreticulin negatively regulates the cell surface expression of cystic fibrosis transmembrane conductance regulator.	CALR CFTR	2.29e-05	2	167	2	16527813
Pubmed	Interaction of newly synthesized apolipoprotein B with calnexin and calreticulin requires glucose trimming in the endoplasmic reticulum.	CALR APOB	2.29e-05	2	167	2	10513896
Pubmed	Mining topoisomerase isoforms in gastric cancer.	TOP2A TOP2B	2.29e-05	2	167	2	32535049
Pubmed	Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development.	TOP2A TOP2B	2.29e-05	2	167	2	1380833
Pubmed	Functional interaction of Oct transcription factors with the family of repeats in Epstein-Barr virus oriP.	POU2F1 POU2F2	2.29e-05	2	167	2	15831936
Pubmed	Differential dimer activities of the transcription factor Oct-1 by DNA-induced interface swapping.	POU2F1 POU2F2	2.29e-05	2	167	2	11583619
Pubmed	Inhibition of cystic fibrosis transmembrane conductance regulator by novel interaction with the metabolic sensor AMP-activated protein kinase.	CFTR PRKAA1	2.29e-05	2	167	2	10862786
Pubmed	Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake.	POU2F1 POU2F2	2.29e-05	2	167	2	31771949
Pubmed	The phospholipid flippase ATP8B1 mediates apical localization of the cystic fibrosis transmembrane regulator.	CFTR ATP8B1	2.29e-05	2	167	2	27301931
Pubmed	Remodeling neuronal ER-PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels.	KCNB2 KCNB1	2.29e-05	2	167	2	30091655
Pubmed	Involvement of human topoisomerase II isoforms in HIV-1 reverse transcription.	TOP2A TOP2B	2.29e-05	2	167	2	23399433
Pubmed	Enhanced processing of UVA-irradiated DNA by human topoisomerase II in living cells.	TOP2A TOP2B	2.29e-05	2	167	2	15044480
Pubmed	C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo.	TOP2A TOP2B	2.29e-05	2	167	2	17526531
Pubmed	Troponin T3 associates with DNA consensus sequence that overlaps with p53 binding motifs.	RRM2B TNNT3	2.29e-05	2	167	2	29596868
Pubmed	DNA topoisomerase II distribution in mouse preimplantation embryos.	TOP2A TOP2B	2.29e-05	2	167	2	11835579
Pubmed	Identification of novel single-stranded DNA binding proteins recognizing octamer motif.	POU2F1 POU2F2	2.29e-05	2	167	2	8185580
Pubmed	Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes.	TOP2A TOP2B	2.29e-05	2	167	2	2556712
Pubmed	CHD6 regulates the topological arrangement of the CFTR locus.	CFTR CHD6	2.29e-05	2	167	2	25631877
Pubmed	Using a biochemical approach to identify the primary dimerization regions in human DNA topoisomerase IIalpha.	TOP2A TOP2B	2.29e-05	2	167	2	10473615
Pubmed	Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain.	TOP2A TOP2B	2.29e-05	2	167	2	9224616
Pubmed	DNA damage response during chromatin remodeling in elongating spermatids of mice.	TOP2A TOP2B	2.29e-05	2	167	2	18032420
Pubmed	Maternal topoisomerase II alpha, not topoisomerase II beta, enables embryonic development of zebrafish top2a-/- mutants.	TOP2A TOP2B	2.29e-05	2	167	2	22111588
Pubmed	Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.	TOP2A TOP2B	2.29e-05	2	167	2	17578914
Pubmed	Disrupted interaction between CFTR and AF-6/afadin aggravates malignant phenotypes of colon cancer.	CFTR AFDN	2.29e-05	2	167	2	24373847
Pubmed	Topoisomerase II alpha and topoisomerase II beta genes: characterization and mapping to human chromosomes 17 and 3, respectively.	TOP2A TOP2B	2.29e-05	2	167	2	1309226
Pubmed	3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase the binding activity and nuclear level of Oct-1 in mononuclear cells.	POU2F1 POU2F2	2.29e-05	2	167	2	12144930
Pubmed	Interplay between myofibers and pro-inflammatory macrophages controls muscle damage in mdx mice.	PRKAA1 DMD	2.29e-05	2	167	2	34471933
Pubmed	Kinetic analysis of human topoisomerase IIalpha and beta DNA binding by surface plasmon resonance.	TOP2A TOP2B	2.29e-05	2	167	2	14596941
Pubmed	Enhanced expression of DNA topoisomerase II genes in human medulloblastoma and its possible association with etoposide sensitivity.	TOP2A TOP2B	2.29e-05	2	167	2	17361331
Pubmed	Molecular cloning and characterization of the human topoisomerase IIalpha and IIbeta genes: evidence for isoform evolution through gene duplication.	TOP2A TOP2B	2.29e-05	2	167	2	10095062
Pubmed	Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.	TOP2A TOP2B	2.29e-05	2	167	2	14996935
Pubmed	p84 forms a negative regulatory complex with p110γ to control PI3Kγ signalling during cell migration.	PIK3R6 PIK3CG	2.29e-05	2	167	2	25753393
Pubmed	Structural organization of the human TOP2A and TOP2B genes.	TOP2A TOP2B	2.29e-05	2	167	2	9795238
Pubmed	The distribution of DNA topoisomerase II isoforms in differentiated adult mouse tissues.	TOP2A TOP2B	2.29e-05	2	167	2	8241259
Pubmed	Phosphatidylinositol 3-kinase regulates the CD4/CD8 T cell differentiation ratio.	PIK3R6 PIK3CG	2.29e-05	2	167	2	12707323
Pubmed	Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cells.	TOP2A TOP2B	2.29e-05	2	167	2	11927602
Pubmed	Topoisomerase II binds importin alpha isoforms and exportin/CRM1 but does not shuttle between the nucleus and cytoplasm in proliferating cells.	TOP2A TOP2B	2.29e-05	2	167	2	17182034
Pubmed	Genetic enhancement of behavioral itch responses in mice lacking phosphoinositide 3-kinase-γ (PI3Kγ).	PIK3R6 PIK3CG	2.29e-05	2	167	2	22168443
Pubmed	Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs).	PIK3R6 PIK3CG	2.29e-05	2	167	2	24190998
Pubmed	Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons.	TOP2A TOP2B	2.29e-05	2	167	2	28700616
Pubmed	Predictors and mechanisms of epilepsy occurrence in cerebral gliomas: What to look for in clinicopathology.	TOP2A TOP2B	2.29e-05	2	167	2	28087392
Pubmed	Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint.	TOP2A TOP2B	2.29e-05	2	167	2	28472494
Pubmed	Transcriptional diversity during lineage commitment of human blood progenitors.	NFIB NFIC	2.29e-05	2	167	2	25258084
Pubmed	Association of immunophenotype with expression of topoisomerase II α and β in adult acute myeloid leukemia.	TOP2A TOP2B	2.29e-05	2	167	2	32218491
Pubmed	Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules.	POU2F1 POU2F2	2.29e-05	2	167	2	8156594
Interaction	FEV interactions	SOX5 ZNF609 C15orf39 POU2F1 BRMS1L NFIB NFIC CHD6 TAF2 ZNF512	4.46e-06	203	157	10	int:FEV
Interaction	SYNE3 interactions	GAK CALR DNAJC25 RCN1 ANKLE2 PRPF40A NBAS ESYT2 CCDC66 PIK3C2A MACF1 LRPAP1 POGLUT2 CNOT1	1.03e-05	444	157	14	int:SYNE3
Interaction	BCAP31 interactions	CALR DNAJC25 CFTR SPCS2 APOB KCNB2 TIMMDC1 ANKLE2 NBAS PTPN2 OSBP ESYT2 LPCAT2 LRPAP1 SLC30A9	2.95e-05	554	157	15	int:BCAP31
Interaction	SOX6 interactions	SOX5 ZNF609 C15orf39 POU2F1 BRMS1L NFIB NFIC NFIX	3.25e-05	157	157	8	int:SOX6
Interaction	DDA1 interactions	ABCA12 RRM2B POU2F1 GTF3C4 PTPN2 SBNO1 NFIC NFIX PRKAA1 MPHOSPH10 TAF2 CRTC2	3.26e-05	368	157	12	int:DDA1
Interaction	RCOR1 interactions	SOX5 CASP8AP2 KDM5B UBR4 ATG2B CKAP5 C15orf39 ZDBF2 BRMS1L NFIB RAB3GAP2 CHD6 ANKRD52 TANGO6	3.35e-05	494	157	14	int:RCOR1
Interaction	WNT6 interactions	SPCS2 PORCN CHEK1	3.76e-05	9	157	3	int:WNT6
Interaction	SOX2 interactions	SOX3 SOX5 KDM5B ZNF609 NT5E CALR UBR4 CKAP5 RCN1 LAMA3 POU2F1 CHD9 SRPK1 RPS19 ZDBF2 BRMS1L ESYT2 NFIB NFIC NFIX MACF1 C3 CHD6 TAF2 ZNF512 CNOT1	3.92e-05	1422	157	26	int:SOX2
Interaction	SOX5 interactions	SOX5 ZNF609 POU2F1 BRMS1L NFIB NFIC NFIX CHD6	4.06e-05	162	157	8	int:SOX5
Interaction	PAX2 interactions	ZNF609 POU2F1 BRMS1L NFIB NFIC NFIX	5.35e-05	85	157	6	int:PAX2
Interaction	PAX7 interactions	ZNF609 POU2F1 BRMS1L NFIB NFIC NFIX CHD6	5.35e-05	124	157	7	int:PAX7
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	SPDYE17 SPDYE10 CCDC146 SPDYE9 SPDYE12 SPDYE11 SPDYE13 SPDYE15 SPDYE8 SPDYE14	7.62e-08	271	169	10	chr7q11
Cytoband	7q11.23	SPDYE10 CCDC146 SPDYE9 SPDYE8 SPDYE14	3.12e-05	97	169	5	7q11.23
GeneFamily	POU class homeoboxes and pseudogenes	POU5F2 POU2F1 POU2F2 POU3F4	8.74e-06	23	105	4	523
GeneFamily	SRY-boxes	SOX3 SOX5 SOX30	1.72e-04	19	105	3	757
GeneFamily	Topoisomerases	TOP2A TOP2B	4.94e-04	6	105	2	1050
GeneFamily	Phosphatidylinositol 3-kinase subunits	PIK3C2A PIK3CG	9.14e-04	8	105	2	831
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE9 SPDYE8	2.12e-03	12	105	2	756
Coexpression	GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN	ASB16-AS1 LRRC39 CHD9 SRPK1 PHKB NBAS RAB3GAP2 CEP41 ZNF512	4.00e-06	197	162	9	M8271
Coexpression	YAGI_AML_WITH_T_8_21_TRANSLOCATION	CALR RCN1 POU2F2 APOB ANKLE2 PRPF40A NBAS OSBP NFIX MACF1 ESPL1	2.15e-05	372	162	11	M19261
Coexpression	GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_6H_UP	KDM5B ABCA12 CFTR APOB SBNO1 NFIB C3 MPHOSPH10	3.25e-05	197	162	8	M8159
Coexpression	GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_DN	ARSK POU2F2 CHD9 PIK3CG AEBP2 AFDN CD302 PXYLP1	3.62e-05	200	162	8	M8486
Coexpression	GSE3203_UNTREATED_VS_IFNB_TREATED_LN_BCELL_UP	MAGI3 ZDBF2 TPCN1 PHKB PIK3CG PRKAA1 TAF2 SLC30A9	3.62e-05	200	162	8	M6795
Coexpression	GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	RAB31 RRM2B POU2F2 CHD9 CHD2 PIK3C2A RNF216 PLCL1	3.62e-05	200	162	8	M9161
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	KIF26B CKAP5 BRMS1L PRPF40A CCDC66 SLC22A8 NFIB NFIX CHD6 TOP2B	1.45e-05	246	156	10	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	GAK ARSK DYNC2H1 CKAP5 POU2F1 CHD9 CHD2 PRPF40A PTPN2 CCDC66 SUGT1 NFIX CEP41 MACF1 PXYLP1 DMD	1.66e-05	629	156	16	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	SOX5 CASP8AP2 KIF26B CKAP5 POU2F1 POU3F4 CHD2 ZDBF2 BRMS1L PRPF40A CCDC66 EML5 SLC22A8 NFIB NFIX CHD6 ZC3H12C MPHOSPH10 DMD TOP2B	3.61e-05	983	156	20	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CKAP5 CHD9 CMYA5 IGSF10 FER MACF1 DMD TOP2B	3.04e-07	176	164	8	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B ABCA12 KIF26B CFTR OBSCN APOB DMD DNAH5	4.26e-07	184	164	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B ABCA12 KIF26B CFTR OBSCN APOB DMD DNAH5	4.26e-07	184	164	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B ABCA12 KIF26B CFTR OBSCN APOB DMD DNAH5	4.26e-07	184	164	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	KDM5B CKAP5 POU2F1 RO60 GTF3C4 PIK3C2A SBF2 CD302	6.11e-07	193	164	8	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	POU3F4 ATP8B1 BRMS1L ANKLE2 CYP39A1 TPCN1 RAB38 GEMIN6	6.87e-07	196	164	8	7be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC1 CCDC146 DYNC2H1 CFAP100 WDR93 KCNB1 DMD DNAH5	7.14e-07	197	164	8	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-OPC_related-Oligodendrocyte/OPC\|2m / Sample Type, Dataset, Time_group, and Cell type.	RCN1 POU2F1 RPS19 EDIL3 RND3 NFIB NFIX ZC3H12C	8.00e-07	200	164	8	3c9a2f02294a9fb892b89e856291bd6423ffa0a9
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-OPC_related\|2m / Sample Type, Dataset, Time_group, and Cell type.	RCN1 POU2F1 RPS19 EDIL3 RND3 NFIB NFIX ZC3H12C	8.00e-07	200	164	8	8e49e7e9b02d8411e4ffae1f5113a2c18f5bf179
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-OPC_related\|10w / Sample Type, Dataset, Time_group, and Cell type.	SOX3 RCN1 RPS19 RND3 NFIB PAH AFDN ZC3H12C	8.00e-07	200	164	8	8f5d98f962ddd8c4658c89ff8a2894de1228562a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-OPC_related-Oligodendrocyte/OPC\|10w / Sample Type, Dataset, Time_group, and Cell type.	SOX3 RCN1 RPS19 RND3 NFIB PAH AFDN ZC3H12C	8.00e-07	200	164	8	345f1eac498cc87fd7bf08e7312608b2d6fe1dd7
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD13B SOX5 C15orf39 TFB1M FER POGLUT2 ESPL1	3.04e-06	168	164	7	b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	RCN1 DICER1 GTF3C4 PTPN2 MPHOSPH10 TAF2 CRTC2	3.28e-06	170	164	7	0f215911b5880eeffeb43230f7eeaf55b612eaf2
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LPCAT2 CCDC42 ZC3H12C ESPL1 TNNT3 DEPDC1B TOP2A	3.41e-06	171	164	7	4ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL C15orf39 POU2F2 LPCAT2 PIK3CG SOCS4 PRKAA1	4.13e-06	176	164	7	d687e6c3f9043f2574d072f815b8c2258f9dc7b5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL C15orf39 POU2F2 LPCAT2 PIK3CG SOCS4 PRKAA1	4.13e-06	176	164	7	4f37854124d77ee64dcb40fd491eaed2ba389891
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL C15orf39 POU2F2 LPCAT2 PIK3CG SOCS4 PRKAA1	4.13e-06	176	164	7	0afba8707b847e5bdf6f38fe4379967631fe2240
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL MYO7B APOB SLC16A12 SLC22A8 PAH DNAH5	4.28e-06	177	164	7	9c7c6824b9011363851f084a500d665f025b026e
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL MYO7B APOB SLC16A12 SLC22A8 PAH DNAH5	4.28e-06	177	164	7	2bf639e9e801e5144462ffc957f5739e0dfcd500
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPL MYO7B MYOM3 SLC16A12 SLC22A8 NFIB PAH	6.59e-06	189	164	7	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPL MYO7B MYOM3 SLC16A12 SLC22A8 NFIB PAH	6.59e-06	189	164	7	13fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAB31 DISC1 POU2F2 CD1E PIK3R6 DHRS9 C3	7.55e-06	193	164	7	3e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAB31 DISC1 POU2F2 CD1E PIK3R6 DHRS9 TRAF3IP3	8.35e-06	196	164	7	291c59b609985167c98a40d4e2caeea2fad74941
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RAB31 DISC1 POU2F2 CD1E PIK3R6 DHRS9 TRAF3IP3	8.63e-06	197	164	7	826cc6baafab13e7ef5cfcf28cd79d0fbf3af38d
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	SOX5 ZNF609 MAGI3 NBAS SBF2 FER DMD	9.22e-06	199	164	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DYNC2H1 KIF26B IGSF10 RND3 SYTL4 MACF1 CD302	9.53e-06	200	164	7	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal\|6m / Sample Type, Dataset, Time_group, and Cell type.	LRRC39 CCDC146 MYOM3 ISM2 HSD17B2 TNNT3 SLC4A5	9.53e-06	200	164	7	13ec8afea86e4a10599c924871ba4e325b0a8013
ToppCell	droplet-Thymus-nan-21m-Myeloid-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POU2F2 CYP39A1 KCNB1 LPCAT2 DNAH17 TNNT3	3.75e-05	168	164	6	69dd747be46e7fbcec571cddd6dee374b9c2507a
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NT5E KIF26B CHRNA5 ZNF594 C3 DEPDC1B	3.75e-05	168	164	6	de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC1 CCDC146 DYNC2H1 CFAP100 WDR93 DNAH5	3.88e-05	169	164	6	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LRRC39 POU5F2 LAMA3 POU3F4 SLC6A1 RND3	4.14e-05	171	164	6	a5634b76476b8b2488a706bbab5141f7bd94631f
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CHEK1 QRICH2 IGSF10 NFIB ESPL1 TOP2A	4.71e-05	175	164	6	a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC1 CCDC146 DYNC2H1 DHRS9 CEP41 DNAH5	4.86e-05	176	164	6	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 KIF26B EDIL3 ESYT2 FER PXYLP1	5.51e-05	180	164	6	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DCDC1 DYNC2H1 CFAP100 WDR93 AFDN DNAH5	5.51e-05	180	164	6	92fb01b91261b3103454924cde56add337b41844
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	MYOM3 OBSCN CMYA5 RNF216 PXYLP1 DMD	5.86e-05	182	164	6	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD9 RPS19 CHD2 SAMD9L MACF1 TOP2B	5.86e-05	182	164	6	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	CCDC146 DYNC2H1 CFAP100 WDR93 DNAH5 SPATA4	5.86e-05	182	164	6	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	6.04e-05	183	164	6	b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|367C / Donor, Lineage, Cell class and subclass (all cells)	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	6.04e-05	183	164	6	cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL APOB SLC16A12 SLC22A8 PAH ALDH4A1	6.22e-05	184	164	6	c86ed59fed687cdaaf7e9c4418d2e3e2c4111cca
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL APOB SLC16A12 SLC22A8 PAH ALDH4A1	6.22e-05	184	164	6	7c256bcfa07c5ff55aad0833e8712b0456b5832b
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL APOB SLC16A12 SLC22A8 PAH ALDH4A1	6.22e-05	184	164	6	3d7dd193a0826cc7a4e454a29236a16c315e5965
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL APOB SLC16A12 SLC22A8 PAH ALDH4A1	6.22e-05	184	164	6	45577ff91c3b2b303acd97239dde2463ea7a429c
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL APOB SLC16A12 SLC22A8 PAH ALDH4A1	6.41e-05	185	164	6	3e3217c99719fd1d2fa94e16be7712a7e5077152
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPL APOB SLC16A12 SLC22A8 PAH ALDH4A1	6.41e-05	185	164	6	0ff4148b4701003d9d594e0da8261176fb13aa59
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	DCDC1 CCDC146 DYNC2H1 CFAP100 WDR93 DNAH5	6.41e-05	185	164	6	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPL MYO7B SLC16A12 TPCN1 SLC22A8 PAH	6.80e-05	187	164	6	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPL MYO7B SLC16A12 TPCN1 SLC22A8 PAH	6.80e-05	187	164	6	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	(09)_Ionocytes-(4)_1wkpi\|(09)_Ionocytes / shred by cell type and Timepoint	LRPAP1 RNF216 C3	6.96e-05	22	164	3	b35fb230042a027b10ef3e7ef09bf13ea1cdc506
ToppCell	Control-CD4+_T_activated\|Control / Disease condition and Cell class	SOX5 ISM2 CD1E SAMD9L DNAH5	7.01e-05	116	164	5	e3d1a90a229f5697b2b715574bb96790a435f73b
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS19 CHD2 PRPF40A SBNO1 NFIB AEBP2	7.01e-05	188	164	6	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	15-Distal-RBC\|Distal / Age, Tissue, Lineage and Cell class	NPL APOB RHD SLC6A1 PAH HSD17B2	7.01e-05	188	164	6	c68ccb1c5c21d13ddac09b16e7d466f0530bbda5
ToppCell	15-Distal-RBC-RBC\|Distal / Age, Tissue, Lineage and Cell class	NPL APOB RHD SLC6A1 PAH HSD17B2	7.01e-05	188	164	6	2534684e4932c1255c24a26ca2277ac7af0a118b
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	KDM5B DISC1 DUS1L NBAS SOCS4 LRRC37B	7.22e-05	189	164	6	99b01893da9f9f7c9528afaffad178285211738b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DCDC1 MYO7B MYOM3 KCNB2 NFIB PAH	7.22e-05	189	164	6	28b502611829e4a24caff2562545c7db97686099
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	NT5E CFTR SLC6A1 PLCL1 HSD17B2 DNAH5	7.43e-05	190	164	6	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	LRRC39 MYOM3 OBSCN CMYA5 PLCL1 DMD	7.43e-05	190	164	6	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 CMYA5 NFIB FER AFDN PXYLP1	7.65e-05	191	164	6	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	LRRC39 MYOM3 OBSCN CMYA5 PLCL1 DMD	7.65e-05	191	164	6	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD9 RND3 NFIB NFIX C3 CD302	7.65e-05	191	164	6	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD9 EDIL3 IGSF10 NFIX C3 CD302	7.87e-05	192	164	6	11088878043a6ff95ba1970361256a82e434b80a
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	MYOM3 OBSCN CMYA5 RNF216 PLCL1 DMD	8.10e-05	193	164	6	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DCDC1 DYNC2H1 CFAP100 IGSF10 NFIX DNAH5	8.10e-05	193	164	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DCDC1 CCDC146 DYNC2H1 CFAP100 DMD DNAH5	8.10e-05	193	164	6	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DCDC1 DYNC2H1 CFAP100 WDR93 DNAH5 SPATA4	8.33e-05	194	164	6	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RCN1 NFIB NFIC NFIX C3 CD302	8.33e-05	194	164	6	9709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CASP8AP2 RCN1 IGSF10 RND3 NFIB TOP2A	8.33e-05	194	164	6	af4bbb2deb5a3913eb58990690fc3c62fbc3708c
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RCN1 NFIB NFIC NFIX C3 CD302	8.33e-05	194	164	6	93b7a9065430740ec31fce4e8c14ffccb498591d
ToppCell	facs-GAT-Fat-18m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RCN1 NFIB NFIC NFIX C3 CD302	8.33e-05	194	164	6	0d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCell	(1)_Dll4_loss-of-function\|World / Stress and Cell class	POU2F2 SRPK1 RPS19 RAB38 TRAF3IP3 TOP2A	8.57e-05	195	164	6	def4b2350e08a36ffddca71ea80ef611f2d437d9
ToppCell	(1)_Dll4_loss-of-function-(0)_LMPP_(LSK_cells)\|World / Stress and Cell class	POU2F2 SRPK1 RPS19 RAB38 TRAF3IP3 TOP2A	8.57e-05	195	164	6	f11cf4b6855a26ff6ea572eebaad2aad6bb2434b
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IGSF10 NFIB NFIC NFIX C3 CD302	8.57e-05	195	164	6	773728703bc8969bff0e1de58fe3e1631add0a0a
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD9 CMYA5 IGSF10 RND3 NFIX CD302	8.57e-05	195	164	6	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 RND3 NFIB C3 DMD DNAH5	8.82e-05	196	164	6	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 RND3 NFIB C3 DMD DNAH5	8.82e-05	196	164	6	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	hematopoetic_progenitors-CD34+_HSC\|hematopoetic_progenitors / Lineage and Cell class	RPS19 IGSF10 CCDC42 SYTL4 NFIB AFDN	8.82e-05	196	164	6	d3e20212c15cff0a3c4e23e8b94715b5822a43e2
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NT5E IGSF10 NFIB MACF1 AFDN DMD	8.82e-05	196	164	6	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NT5E IGSF10 NFIB MACF1 AFDN DMD	8.82e-05	196	164	6	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	DYNC2H1 LAMA3 CHD9 IGSF10 SAMD9L CD302	9.06e-05	197	164	6	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DYNC2H1 IGSF10 RND3 SYTL4 MACF1 CD302	9.06e-05	197	164	6	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	Bronchial_Brush-Epithelial\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	CCDC146 DYNC2H1 RND3 NFIB DHRS9 DNAH5	9.06e-05	197	164	6	272c7f4e582ef57564450540242b0db766b78328
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-Treg\|ICU-SEP / Disease, condition lineage and cell class	EFCAB5 OBSCN ZDBF2 PLCL1 TRAF3IP3 POGLUT2	9.06e-05	197	164	6	c3ee2d522fbfe67069ddba2d1abfc4f5ca230c26
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-G\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	SLC16A12 IGSF10 MACF1 LRPAP1 CD302 HSD17B2	9.06e-05	197	164	6	a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCell	Epithelial_cells-Epithelial_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	MYOM3 SLC16A12 SLC22A8 NFIB PAH ALDH4A1	9.32e-05	198	164	6	52e9d41a1726bc1140df6baec9f17a534448ac8b
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	CCDC146 CFAP100 DHRS9 C3 HSD17B2 DNAH5	9.32e-05	198	164	6	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	moderate-Epithelial-Secretory\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RCN1 MAGI3 RND3 NFIB DHRS9 C3	9.32e-05	198	164	6	7d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	CCDC146 CFAP100 DHRS9 C3 HSD17B2 DNAH5	9.32e-05	198	164	6	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	Epithelial_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	MYOM3 SLC16A12 SLC22A8 NFIB PAH ALDH4A1	9.32e-05	198	164	6	eeec789d226171f30799577cc37c07bdced2e3cb
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DYNC2H1 IGSF10 RND3 SYTL4 MACF1 CD302	9.58e-05	199	164	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	distal-1-Epithelial-Ciliated\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	9.58e-05	199	164	6	4120e4a2bc05adebe1e1e9670ed7ea55142eb83d
ToppCell	distal-3-Epithelial-Ciliated\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	9.58e-05	199	164	6	7e5f29f4ec1fea92f2c0064eea151d2d474ef904
ToppCell	distal-Epithelial-Ciliated-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	9.58e-05	199	164	6	6ce0df4a6f4d9353919e26ffab97c9ec89911da6
ToppCell	Caecum-Dendritic_cell\|Caecum / Region, Cell class and subclass	RAB31 RND3 CD1E LPCAT2 CD302 TOP2A	9.85e-05	200	164	6	b91d3d7505a022ca360ab5b3f9955753d111f974
ToppCell	mLN-Mast_cell-Mast\|mLN / Region, Cell class and subclass	NDST2 PIK3R6 KCNB1 LPCAT2 DHRS9 ALDH4A1	9.85e-05	200	164	6	81ea6e7a3940277751faf9097b30198159998c7b
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	LAMA3 MAGI3 EML5 AFDN C3 ALDH4A1	9.85e-05	200	164	6	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	Caecum-Dendritic_cell-cycling_DCs\|Caecum / Region, Cell class and subclass	RND3 CD1E LPCAT2 CD302 DEPDC1B TOP2A	9.85e-05	200	164	6	608be9bfe74f8d3202aa92b2905452a06f340f76
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	9.85e-05	200	164	6	5abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCell	mLN-Mast_cell\|mLN / Region, Cell class and subclass	NDST2 PIK3R6 KCNB1 LPCAT2 DHRS9 ALDH4A1	9.85e-05	200	164	6	9a5f1d99d8d160923d4d0fbbf9ad48a26f8a4fad
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DCDC1 CCDC146 CFAP100 WDR93 DNAH5 SPATA4	9.85e-05	200	164	6	9c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
Drug	7-biopterin	NFIB NFIC NFIX PAH	1.60e-06	13	160	4	CID005488923
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD2 CHD6	5.00e-06	7	156	3	DOID:0050834 (implicated_via_orthology)
Disease	B cell deficiency (implicated_via_orthology)	TOP2A TOP2B	2.78e-05	2	156	2	DOID:2115 (implicated_via_orthology)
Disease	immune system disease (implicated_via_orthology)	POU2F1 POU2F2	8.30e-05	3	156	2	DOID:2914 (implicated_via_orthology)
Disease	Myoclonic-astatic epilepsy	CHD2 SLC6A1	8.30e-05	3	156	2	cv:C0393702
Disease	Autism Spectrum Disorders	SOX5 CHD2 PAH CEP41 TET3	9.04e-05	85	156	5	C1510586
Disease	esophageal adenocarcinoma, Barrett's esophagus	CFTR APOB PLCL1	5.84e-04	31	156	3	EFO_0000280, EFO_0000478
Disease	Malignant neoplasm of breast	DYNC2H1 UBR4 OBSCN POU2F1 ATP8B1 CHEK1 RHD PHKB SBNO1 ANKEF1 PRKAA1 PUS1 MACF1 DMD TOP2A	5.98e-04	1074	156	15	C0006142
Disease	lung cancer (is_implicated_in)	CALR SOX30 CFTR CHRNA5	6.49e-04	74	156	4	DOID:1324 (is_implicated_in)
Disease	Deafness, Sensorineural, Autosomal-Mitochondrial Type	POU3F4 TFB1M	7.62e-04	8	156	2	C1857332
Disease	memory impairment	PRPF40A LRRC37B	7.62e-04	8	156	2	EFO_0001072
Disease	membranous glomerulonephritis (implicated_via_orthology)	LRPAP1 C3	9.76e-04	9	156	2	DOID:10976 (implicated_via_orthology)
Disease	autism spectrum disorder (implicated_via_orthology)	KDM5B NDST2 CHD9 CHD2 CHD6	1.31e-03	152	156	5	DOID:0060041 (implicated_via_orthology)
Disease	Colorectal Carcinoma	ABCA12 CALR CFTR OBSCN RCN1 APOB KCNB2 RAB38 OSBP TRAF3IP3 DMD	1.32e-03	702	156	11	C0009402
Disease	virologic response measurement, response to abacavir	IGSF10 PIK3C2A FER	1.43e-03	42	156	3	EFO_0006905, EFO_0006906
Disease	Macrocephaly	NFIB TET3	1.48e-03	11	156	2	C0221355
Disease	alpha angle measurement	SOX5 TFB1M	1.48e-03	11	156	2	EFO_0020071
Disease	Myoclonic Astatic Epilepsy	CHD2 SLC6A1	1.48e-03	11	156	2	C0393702
Disease	Oligospermia	DICER1 TPCN1	1.77e-03	12	156	2	C0028960
Disease	acute myeloid leukemia (implicated_via_orthology)	TOP2A TOP2B	1.77e-03	12	156	2	DOID:9119 (implicated_via_orthology)
Disease	Myeloproliferative disease	CALR ATG2B	1.77e-03	12	156	2	C0027022
Disease	mortality	SOX5 GAK EDIL3 DICER1 DMD	2.31e-03	173	156	5	EFO_0004352
Disease	Schizophrenia	SOX5 DISC1 CHEK1 CMYA5 DICER1 CHRNA5 RHD SLC6A1 EML5 KCNB1 SBNO1 PAH	2.64e-03	883	156	12	C0036341
Disease	Intellectual Disability	DISC1 RRM2B NFIB PUS1 MACF1 ALDH4A1 TAF2 TET3	2.69e-03	447	156	8	C3714756
Disease	Ciliopathies	DYNC2H1 CFTR CEP41 DNAH5	2.81e-03	110	156	4	C4277690
Disease	sickle cell anemia (is_implicated_in)	APOB C3	3.17e-03	16	156	2	DOID:10923 (is_implicated_in)
Disease	ankle brachial index	NBAS DMD	3.17e-03	16	156	2	EFO_0003912
Disease	response to statin	SOX5 DISC1 APOB	3.27e-03	56	156	3	GO_0036273
Disease	alpha-L-iduronidase measurement	GAK FGFRL1	3.59e-03	17	156	2	EFO_0020139
Disease	Familial Progressive Myoclonic Epilepsy	CHD2 AFG3L2	3.59e-03	17	156	2	C0751777
Disease	Atypical Inclusion-Body Disease	CHD2 AFG3L2	3.59e-03	17	156	2	C0751776
Disease	Myoclonic Epilepsies, Progressive	CHD2 AFG3L2	3.59e-03	17	156	2	C0751778
Disease	Biotin-Responsive Encephalopathy	CHD2 AFG3L2	3.59e-03	17	156	2	C0751780
Disease	May-White Syndrome	CHD2 AFG3L2	3.59e-03	17	156	2	C0751782
Disease	Dentatorubral-Pallidoluysian Atrophy	CHD2 AFG3L2	3.59e-03	17	156	2	C0751781
Disease	ankle injury	CHD9 NFIB TAF2	3.79e-03	59	156	3	EFO_1002021
Disease	diet measurement	SOX5 KIF26B C16orf78 POU2F2 CHD2 APOB RND3 NBAS NFIX CHD6 DNAH5 CNOT1 CRTC2	3.89e-03	1049	156	13	EFO_0008111
Disease	Myeloid Leukemia	ATG2B TOP2B	4.02e-03	18	156	2	C0023470
Disease	Leukemia, Monocytic, Chronic	ATG2B TOP2B	4.02e-03	18	156	2	C0023466
Disease	Action Myoclonus-Renal Failure Syndrome	CHD2 AFG3L2	4.02e-03	18	156	2	C0751779
Disease	loneliness measurement	EDIL3 SLC6A1 MACF1 PLCL1	4.32e-03	124	156	4	EFO_0007865
Disease	response to methotrexate, neurotoxicity	MACF1 PLCL1	4.48e-03	19	156	2	EFO_0011057, GO_0031427
Disease	unipolar depression	SOX5 CASP8AP2 DCDC1 POU5F2 DYNC2H1 DISC1 C16orf78 BRMS1L NBAS KCNB1 FER CHD6 DMD SLC30A9	4.91e-03	1206	156	14	EFO_0003761
Disease	PR interval	EFCAB5 ABCA12 OBSCN FER MACF1 CHD6 CNOT1 THAP12	4.97e-03	495	156	8	EFO_0004462
Disease	blood lead measurement	PTPN2 KCNB1 SPESP1	5.20e-03	66	156	3	EFO_0007040

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSPDPWKRDAKEKLE	AFDN	1511	P55196
LEKVSHDAIKIPKWS	ARSK	231	Q6UWY0
LDEVPKGKLHLRLEW	ESYT2	491	A0FGR8
DSGKIKLLLHWMPED	AEBP2	441	Q6ZN18
PLSPAKAEDFRKLWK	ANKLE2	526	Q86XL3
LKWEDKDITLHPQGL	ERVK11-1	176	P61568
EWDRELASKKNPKLI	CFTR	56	P13569
WKKIDSAPLALLHKI	CHEK1	231	O14757
SLPEGLKDWNKEREK	AFG3L2	771	Q9Y4W6
DPKSKRHLWKIISEE	ABCA12	2421	Q86UK0
LDTLKKQWKGPDDIL	CD302	76	Q8IX05
AENKWRFTPEDLKKI	CEP41	296	Q9BYV8
LTTAKDKNRWEDPGK	C3	1211	P01024
EWLERRQGKKKQAPE	C16orf78	36	Q8WTQ4
KLEKSLAWKEAQPEL	DUS1L	436	Q6P1R4
IEAALAARKEWDLKP	ALDH4A1	106	P30038
DLKWKNLDHKTPRAV	ANKEF1	276	Q9NU02
ILDDKSKELPHWVLS	DEPDC1B	231	Q8WUY9
ESKVLRKILKAWDPF	ASB16-AS1	176	Q495Z4
LKEEWPALGDSEILK	DMD	1071	P11532
LDDPRLEKLWHKAKT	LRPAP1	146	P30533
IKERKRKWTPLHAAA	ANKRD52	646	Q8NB46
ASESPSIWLLEKKKE	CCDC42	36	Q96M95
ALPLSSAEKRKAKWE	DICER1	1011	Q9UPY3
WELKTPEKQLLETLK	CASP8AP2	1336	Q9UKL3
KRKTPLKVLEEWKTH	DISC1	741	Q9NRI5
ERGPWFKKSLQKEIL	ATG2B	766	Q96BY7
WPSESDKIQKHRKRL	ATP8B1	1171	O43520
DGKLDKDEIRHWILP	RCN1	261	Q15293
LLSEKPEIKQKWASR	NFIB	61	O00712
LKKWVKELKEHGPEN	RAB31	96	Q13636
VAKWKNDLDSKLSLP	RAB38	101	P57729
ELDPVKQLLEDRWKS	QRICH2	1381	Q9H0J4
QKRWKELSKEDLSPA	PTPN2	286	P17706
QKFKAKLWLCEEHPL	ANKRD13B	366	Q86YJ7
VWLSKEKDILDKPQS	RAB3GAP2	776	Q9H2M9
RKLEEKHPKASAQRW	DCDC1	851	M0R2J8
KKWHLLRLAPENLKT	FAM166C	161	A6NJV1
LGEKPEIKQKWASRL	NFIX	61	Q14938
SREAEGWKEDPLNKK	MAGEB18	96	Q96M61
WLDPRLCKKAKAPED	MAGI3	321	Q5TCQ9
KLTNKLPDLWRKIES	LAMA3	2341	Q16787
KLHWPEQELAKKSIL	KIAA0895	61	Q8NCT3
IEKLEHKLNQAPEKW	SBF2	1646	Q86WG5
WLKREEEVKKETAHP	KIF26B	1441	Q2KJY2
KIEKEEWKTLPSSLL	LRRC39	66	Q96DD0
RSDKENWPKTLKLAL	DDX58	161	O95786
NWPKTLKLALEKERN	DDX58	166	O95786
KDTLGLPSEEWKLLA	ISM2	376	Q6H9L7
KKKWTLSLKNLRPED	FGFRL1	201	Q8N441
SKFDWLDLDPLSKPK	PIK3C2A	266	O00443
LDEWKKKLESPNREI	DDHD2	146	O94830
KLKPLLEKWLNDAET	POU2F2	256	P09086
RPLLKKWLKEVEAEN	POU5F2	181	Q8N7G0
IASLEKELLEKKPWQ	MPHOSPH10	371	O00566
VVSPKNLKKDLAERW	LRRC37B	186	Q96QE4
NLKKDLAERWSLPEI	LRRC37B	191	Q96QE4
WDDKAKSLLKARPRH	KDM5B	971	Q9UGL1
ELSKKLAEVWKQLPE	HMGXB4	436	Q9UGU5
LAEVWKQLPEKDKLI	HMGXB4	441	Q9UGU5
DLNPDWRLSTEKRKK	NBAS	366	A2RRP1
WFERKKDPVTKELTH	OSBP	771	P22059
VHELSRDKKKDTVPW	PAH	106	P00439
PLTELKHLWENLGEK	MACF1	6196	Q9UPN3
KLKPLLEKWLNDAEN	POU2F1	341	P14859
CKLKPLLNKWLEEAD	POU3F4	246	P49335
RIKWKHRGKDIELPS	THAP12	646	O43422
KELLKEKRVPSNASW	PRPF40A	401	O75400
PVHWLKDRKAIRKSQ	OBSCN	2856	Q5VST9
RKLKLDWDGVRKHLD	LPCAT2	351	Q7L5N7
EKDHLEWDLTVSKPL	PORCN	276	Q9H237
QEEELKKKLANDPRW	DNAJC25	326	Q9H1X3
KDTDPLKLKLLDWIE	GAK	1211	O14976
LEKFKARWDQLKPGD	DYNC2H1	1051	Q8NCM8
LDETELKSKPEHTWK	EFCAB5	101	A4FU69
WEPRKARLDKQGKVN	EDIL3	351	O43854
WVRPVEHLNDKIKIK	CHRNA5	61	P30532
PLKDFSLWEKTGLKE	APOB	3146	P04114
GESELKRKVKPEAWL	CD1E	201	P15812
EWLKLPVDQKCEHKL	CKAP5	6	Q14008
DDAPKRKDLEKWLKE	CHD9	2501	Q3L8U1
WELLRLDSSKKKLPS	ESPL1	1531	Q14674
IDPQHWAALLEKAKK	IGSF10	751	Q6WRI0
KRKKLWDLLEKPNSS	KCNB1	171	Q14721
RKKLWDLLEKPNSSV	KCNB2	176	Q92953
LKLQELPEHWANTKK	DNAH17	1166	Q9UFH2
SAKRWKKLVESEAPE	DNAH17	3796	Q9UFH2
WELIKTDPELKLTDK	CHD2	1281	O14647
VKHELLKEPWKESAE	CHD6	1991	Q8TD26
PKDKKWILSHEDVIL	FER	551	P16591
LDDKHLLKPWDAKKL	CRTC2	221	Q53ET0
EHELPLSLWGEIKKK	CMYA5	1526	Q8N3K9
LEDDWDFLPPKKIKD	CALR	196	P27797
KLRWHLVKKEEEPLN	CCDC66	771	A2RUB6
LSPKEWLEEQEKKHS	CFAP100	266	Q494V2
LWNDELQSRKKRKDP	BRMS1L	181	Q5PSV4
EPELFKPERWKKANL	CYP39A1	381	Q9NYL5
WKFIPERKLKDAVHI	EML5	591	Q05BV3
PEDLEERKNSLKKWL	GEMIN6	96	Q8WXD5
LKKWLEKNHIPITEQ	GEMIN6	106	Q8WXD5
EKKLAIWEQLSPDIK	DHRS9	221	Q9BPW9
WEKLEKDILDHLPAE	HSD17B2	276	P37059
DLENWSLRAKKPKQE	SLC22A8	506	Q8TCC7
DDENDPWLIRKDHKK	SBNO1	771	A3KN83
LKQLLKKEWLRSPDN	CCDC124	196	Q96CT7
VIKEPNDLLKLWKHE	DNAH5	2811	Q8TE73
ISEWKDKPTHEILQK	PHKB	716	Q93100
RPETLDSVLKKWKGE	RND3	106	P61587
LKPWTKDILINFLKE	NPL	116	Q9BXD5
DSWKLDKKLDHCLPL	SYTL4	466	Q96C24
RAKELQGPWDLEKLH	TSGA10IP	311	Q3SY00
KRLGADWKLLTDAEK	SOX3	171	P41225
PEWVDTVKLAKHKEL	RPS19	31	P39019
KKAADLPDRDTWKGR	SLC6A1	36	P30531
LKRKSPSDLWKEDLA	TOP2B	1176	Q02880
TWLLEQPGKEEKRKT	SLC16A12	16	Q6ZSM3
DRVWEDGEHPAKKLK	PUS1	56	Q9Y606
EKLKDLIHCWAESPK	SAMD9L	716	Q8IVG5
PSELWKHVDELKVLK	TAF2	131	Q6P1X5
RWSLHKKVERDPGKS	PIK3R6	36	Q5UE93
SRKRNKPKWDLDDEI	SOCS4	241	Q8WXH5
LEDPVIKRLLAWDKD	SPDYE10	116	P0DUX0
LEDPVIKRLLAWDKD	SPDYE11	116	P0DTA3
LEDPVIKRLLAWDKD	SPDYE8	116	P0DUD1
KVEKAFSESLKRPWE	TFB1M	116	Q8WVM0
KHPESWNNDDILKKI	SPESP1	216	Q6UW49
KKHKLLPNDWSADQL	PXYLP1	186	Q8TE99
KALSDAIKKWQELSP	RNF216	406	Q9NWF9
DLKHITKLKPWGLFE	SRPK1	596	Q96SB4
LLGEKPEVKQKWASR	NFIC	61	P08651
LKWRPDEEILKALDA	RO60	341	P10155
LGLEWNKLSEEQKKP	SOX30	371	O94993
EDPSIKADINKWRIK	NT5E	316	P21589
KDIREHEWFKQDLPK	PRKAA1	271	Q13131
EKGLPLNKEIEKEWL	CCDC146	856	Q8IYE0
EKAWALLQKRIPKTH	COASY	546	Q13057
GDNLWIDKLPKERTK	C12orf71	111	A8MTZ7
AEEKTWLPSCRKEKL	C15orf39	436	Q6ZRI6
HWCPEREKVKLLTLK	C11orf40	31	Q8WZ69
KLDKWLTDKIREHGE	CNOT1	596	A5YKK6
VLNHWLKEKSPTEEK	PIK3CG	906	P48736
LSKDLPHWNKLKADE	RRM2B	71	Q7LG56
RKLGRKLNPEWFDVK	SPATA4	221	Q8NEY3
EKLLTKKDQALPVWS	TRAF3IP3	431	Q9Y228
LQALRWEPSKKDLEK	PLCL1	141	Q15111
LLLNLKIWKAPHEAK	RHD	386	Q02161
GRSGLLDKWKIDDKP	SPCS2	31	Q15005
LEDPVIKRLLAWDKD	SPDYE12	116	P0DUX1
LEDPVIKRLLAWDKD	SPDYE13	116	A0A494C0Z2
LEDPVIKRLLAWDKD	SPDYE14	116	P0DUD3
LEDPVIKRLLAWDKD	SPDYE15	116	P0DUD4
LEDPVIKRLLAWDKD	SPDYE17	116	P0DUD2
KALHELKLEEWKGRL	TIMMDC1	226	Q9NPL8
EREAALKEEWKQKPS	ZNF609	1031	O15014
LWKEHVDLENKIVKP	ZDBF2	1266	Q9HCK1
LQKPVKEINLWKEDH	ZDBF2	1381	Q9HCK1
KLLRDEIADKAEWPQ	TANGO6	71	Q9C0B7
KDIWSKEKTCDRLPK	NDST2	591	P52849
LAWIDNILPEKEKKE	SLC4A5	1066	Q9BY07
LKKPEAVRWEKLEGQ	SUGT1	246	Q9Y2Z0
DLVRWKILKDKHIPQ	GTF3C4	541	Q9UKN8
KLFGALKSEEKLWDP	TET3	1591	O43151
ELFVNLGDWPLEKKK	POGLUT2	231	Q6UW63
LWPEKAALKVLGKDH	nan	166	A8MV72
KAKKNREHWFDELPR	TPCN1	411	Q9ULQ1
DTLKRKSPSDLWKED	TOP2A	1156	P11388
LWPEKAALKVLGKDH	nan	196	A8MUI8
LWPEKAALKVLGKDH	nan	196	A8MUA0
RKLEKNPEKEEEHWA	WDR93	656	Q6P2C0
HLGEDKLRDKAKELW	TNNT3	201	P45378
EDRLLKHWVSPLKDA	ZNF594	41	Q96JF6
WGSPEALAREKKLRK	SLC30A9	181	Q6PML9
LEDPVIKRLLAWDKD	SPDYE9	116	A0A494C191
ETPSIEKLLSKDWKD	SOX5	161	P35711
NEKPEWKKFIDERLL	ZC3H12C	361	Q9C0D7
KKHIPSAKNLDADIW	UBR4	4696	Q5T4S7
WKSLPEADLHLTKAL	WDR87	2851	Q6ZQQ6
AELAKEWPKRKVLQD	ZNF512	356	Q96ME7
WPEKAALKVLGKDHL	nan	196	A6NL46
PHDEKKFKQLLSWRA	WDR64	851	B1ANS9
DSLREVSDWVKKNKP	MYO7B	1861	Q6PIF6
IWLHILDPKDSDKGK	MYOM3	1276	Q5VTT5