Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone kinase activity	MST1 RPS6KA5 PRKDC ATM	4.11e-06	28	78	4	GO:0035173
GeneOntologyMolecularFunction	DNA-dependent protein kinase activity	PRKDC ATM	4.51e-05	3	78	2	GO:0004677
GeneOntologyMolecularFunction	histone H2AXS139 kinase activity	PRKDC ATM	4.51e-05	3	78	2	GO:0035979
GeneOntologyMolecularFunction	Krueppel-associated box domain binding	TRIM28 HDAC1	4.51e-05	3	78	2	GO:0035851
GeneOntologyMolecularFunction	nuclear glucocorticoid receptor binding	PSMC3IP PIAS2 SMAD3	6.23e-05	20	78	3	GO:0035259
GeneOntologyMolecularFunction	histone H2AX kinase activity	PRKDC ATM	1.49e-04	5	78	2	GO:0141003
GeneOntologyMolecularFunction	neuroligin family protein binding	NRXN1 NRXN2	1.49e-04	5	78	2	GO:0097109
GeneOntologyMolecularFunction	3'-5' RNA helicase activity	SUPV3L1 DHX9	2.24e-04	6	78	2	GO:0034458
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	MOK MST1 POLR1A RPS6KA5 BMP2K TRIM28 POLR2B DGKK PPIP5K1 PRKDC ATM TTK	2.67e-04	938	78	12	GO:0016772
GeneOntologyMolecularFunction	promoter-specific chromatin binding	TRIM28 SMAD3 HDAC1 DHX9	3.13e-04	83	78	4	GO:1990841
GeneOntologyMolecularFunction	SUMO transferase activity	PIAS4 TRIM28 PIAS2	3.73e-04	36	78	3	GO:0019789
GeneOntologyMolecularFunction	kinase activity	MOK MST1 RPS6KA5 BMP2K TRIM28 DGKK PPIP5K1 PRKDC ATM TTK	7.60e-04	764	78	10	GO:0016301
GeneOntologyMolecularFunction	co-SMAD binding	USP9Y SMAD3	9.69e-04	12	78	2	GO:0070410
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	AGO4 POLR1A DIS3L SUPV3L1 POLR2B RNASEK DHX9	1.22e-03	417	78	7	GO:0140098
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	NPM1 PSMC3IP PRKDC PIAS2 SMAD3 HDAC1 DHX9	1.22e-03	417	78	7	GO:0061629
GeneOntologyMolecularFunction	transcription coregulator activity	PIAS4 NPM1 LMO1 TRIM28 PSMC3IP PIAS2 HDAC1 DHX9	1.56e-03	562	78	8	GO:0003712
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	MOK MST1 RPS6KA5 BMP2K TRIM28 DGKK PRKDC ATM TTK	1.75e-03	709	78	9	GO:0016773
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	NPM1 LMO1 PSMC3IP PRKDC PIAS2 SMAD3 HDAC1 DHX9	1.94e-03	582	78	8	GO:0140297
GeneOntologyMolecularFunction	histone modifying activity	MST1 RPS6KA5 PRKDC ATM HDAC1	2.03e-03	229	78	5	GO:0140993
GeneOntologyMolecularFunction	protein kinase activity	MOK MST1 RPS6KA5 BMP2K TRIM28 PRKDC ATM TTK	2.34e-03	600	78	8	GO:0004672
Domain	TPR-like_helical_dom	SAMD9 POLR1A PRKDC TTK IFIT2 ANAPC5 CFAP46	6.30e-05	233	80	7	IPR011990
Domain	ARM-type_fold	DNAJC13 PPP2R5D TERB1 ARFGEF2 ARFGEF1 PRKDC ATM USP9Y	1.01e-04	339	80	8	IPR016024
Domain	DUF1981	ARFGEF2 ARFGEF1	1.08e-04	4	80	2	PF09324
Domain	PINIT	PIAS4 PIAS2	1.08e-04	4	80	2	IPR023321
Domain	Sec7_N	ARFGEF2 ARFGEF1	1.08e-04	4	80	2	IPR032691
Domain	Sec7_N	ARFGEF2 ARFGEF1	1.08e-04	4	80	2	PF12783
Domain	PINIT	PIAS4 PIAS2	1.08e-04	4	80	2	PS51466
Domain	DCB_dom	ARFGEF2 ARFGEF1	1.08e-04	4	80	2	IPR032629
Domain	PINIT	PIAS4 PIAS2	1.08e-04	4	80	2	PF14324
Domain	DCB	ARFGEF2 ARFGEF1	1.08e-04	4	80	2	PF16213
Domain	Sec7_C	ARFGEF2 ARFGEF1	1.08e-04	4	80	2	IPR015403
Domain	FATC	PRKDC ATM	1.80e-04	5	80	2	PF02260
Domain	FAT	PRKDC ATM	2.69e-04	6	80	2	PS51189
Domain	FATC	PRKDC ATM	2.69e-04	6	80	2	PS51190
Domain	FAT	PRKDC ATM	2.69e-04	6	80	2	PF02259
Domain	PIK-rel_kinase_FAT	PRKDC ATM	2.69e-04	6	80	2	IPR003151
Domain	FATC_dom	PRKDC ATM	2.69e-04	6	80	2	IPR003152
Domain	PIK_FAT	PRKDC ATM	2.69e-04	6	80	2	IPR014009
Domain	FATC	PRKDC ATM	2.69e-04	6	80	2	SM01343
Domain	zf-MIZ	PIAS4 PIAS2	3.75e-04	7	80	2	PF02891
Domain	ZF_SP_RING	PIAS4 PIAS2	3.75e-04	7	80	2	PS51044
Domain	Syndecan	NRXN1 NRXN2	3.75e-04	7	80	2	PF01034
Domain	Syndecan/Neurexin_dom	NRXN1 NRXN2	3.75e-04	7	80	2	IPR027789
Domain	Znf_MIZ	PIAS4 PIAS2	4.99e-04	8	80	2	IPR004181
Domain	ARM-like	DNAJC13 TERB1 ARFGEF2 ARFGEF1 PRKDC USP9Y	1.06e-03	270	80	6	IPR011989
Domain	Neurexin-like	NRXN1 NRXN2	1.59e-03	14	80	2	IPR003585
Domain	4.1m	NRXN1 NRXN2	1.59e-03	14	80	2	SM00294
Domain	-	ARFGEF2 ARFGEF1	1.83e-03	15	80	2	1.10.1000.11
Domain	Sec7	ARFGEF2 ARFGEF1	1.83e-03	15	80	2	PF01369
Domain	Sec7_alpha_orthog	ARFGEF2 ARFGEF1	1.83e-03	15	80	2	IPR023394
Domain	PI3/4_kinase_CS	PRKDC ATM	1.83e-03	15	80	2	IPR018936
Domain	Sec7	ARFGEF2 ARFGEF1	2.09e-03	16	80	2	SM00222
Domain	-	PRKDC ATM	2.09e-03	16	80	2	1.10.1070.11
Domain	SEC7	ARFGEF2 ARFGEF1	2.09e-03	16	80	2	PS50190
Domain	Sec7_dom	ARFGEF2 ARFGEF1	2.09e-03	16	80	2	IPR000904
Domain	PI3Kc	PRKDC ATM	2.09e-03	16	80	2	SM00146
Domain	-	DNAJC13 TERB1 ARFGEF2 ARFGEF1 PRKDC	2.65e-03	222	80	5	1.25.10.10
Domain	PI3/4_kinase_cat_dom	PRKDC ATM	2.65e-03	18	80	2	IPR000403
Domain	PI3_PI4_kinase	PRKDC ATM	2.65e-03	18	80	2	PF00454
Domain	PI3_4_KINASE_3	PRKDC ATM	2.65e-03	18	80	2	PS50290
Domain	PI3_4_KINASE_1	PRKDC ATM	2.65e-03	18	80	2	PS00915
Domain	PI3_4_KINASE_2	PRKDC ATM	2.65e-03	18	80	2	PS00916
Domain	-	PIAS4 PIAS2	3.61e-03	21	80	2	1.10.720.30
Domain	SAP	PIAS4 PIAS2	3.96e-03	22	80	2	PF02037
Domain	SAP	PIAS4 PIAS2	4.32e-03	23	80	2	SM00513
Domain	SAP	PIAS4 PIAS2	5.10e-03	25	80	2	PS50800
Domain	SAP_dom	PIAS4 PIAS2	5.10e-03	25	80	2	IPR003034
Domain	TPR_REGION	PRKDC IFIT2 ANAPC5 CFAP46	5.52e-03	165	80	4	PS50293
Domain	TPR	PRKDC IFIT2 ANAPC5 CFAP46	5.52e-03	165	80	4	PS50005
Pathway	WP_HIPPOCAMPAL_SYNAPTOGENESIS_AND_NEUROGENESIS	NRXN1 NRXN2 RPS6KA5 HNRNPL	5.17e-06	27	61	4	M45550
Pathway	WP_CELL_CYCLE	PRKDC ATM TTK ANAPC5 SMAD3 HDAC1	1.27e-05	120	61	6	M39650
Pathway	KEGG_CELL_CYCLE	PRKDC ATM TTK ANAPC5 SMAD3 HDAC1	1.61e-05	125	61	6	M7963
Pathway	REACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS	PIAS4 NPM1 TRIM28 PIAS2	3.78e-05	44	61	4	M27295
Pathway	WP_ANDROGEN_RECEPTOR_SIGNALING	PIAS4 PSMC3IP PIAS2 SMAD3 HDAC1	4.49e-05	91	61	5	M39700
Pathway	KEGG_MEDICUS_REFERENCE_ALTERNATIVE_PATHWAY_OF_COMPLEMENT_CASCADE_C3B_BREAKDOWN	CFH CFI	1.83e-04	5	61	2	M47875
Pathway	BIOCARTA_G1_PATHWAY	ATM SMAD3 HDAC1	2.34e-04	28	61	3	M648
Pathway	PID_BARD1_PATHWAY	NPM1 PRKDC ATM	2.60e-04	29	61	3	M258
Pathway	WP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY	PIAS4 TRIM28 PIAS2 SMAD3 HDAC1 ZIC2 DHX9	3.07e-04	301	61	7	MM15983
Pubmed	Repression of Smad transcriptional activity by PIASy, an inhibitor of activated STAT.	PIAS4 SMAD3 HDAC1	2.42e-07	6	81	3	12904571
Pubmed	Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.	TRIM28 PRKDC ANAPC5 HNRNPL HDAC1 DHX9	3.20e-07	116	81	6	21549307
Pubmed	Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail.	PRKDC ATM HDAC1	6.76e-07	8	81	3	22184063
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	NPM1 TRIM28 POLR2B PRKDC PIAS2 HNRNPL SMAD3 HDAC1 ZIC2 DHX9	1.05e-06	583	81	10	29844126
Pubmed	TGFβ pathway is required for viable gestation of Fanconi anemia embryos.	PTPRC PRKDC SMAD3	1.44e-06	10	81	3	36441774
Pubmed	Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.	CUL2 NPM1 TRIM28 POLR2B PRKDC HNRNPL DHX9	1.72e-06	244	81	7	30349055
Pubmed	Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway.	PTPRC PRKDC ATM	1.98e-06	11	81	3	11551930
Pubmed	Sumoylation of FOXP2 Regulates Motor Function and Vocal Communication Through Purkinje Cell Development.	PIAS4 CALB1 PIAS2	1.98e-06	11	81	3	27009683
Pubmed	Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis.	PIAS4 PIAS2 HDAC1	2.64e-06	12	81	3	30612578
Pubmed	MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.	TRIM28 PRKDC ATM	2.64e-06	12	81	3	30017584
Pubmed	The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF.	TRIM28 POLR2B PRKDC DHX9	2.86e-06	42	81	4	34244791
Pubmed	The contribution of rare and common variants in 30 genes to risk nicotine dependence.	NRXN1 NRXN2 CHRNA2	4.35e-06	14	81	3	25450229
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	PIAS4 TRIM28 PRKDC PIAS2 HDAC1	5.10e-06	106	81	5	19394292
Pubmed	Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis.	PRKDC ATM	5.36e-06	2	81	2	11231155
Pubmed	Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation.	PRKDC ATM	5.36e-06	2	81	2	10464290
Pubmed	Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.	PRKDC ATM	5.36e-06	2	81	2	27939942
Pubmed	The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.	PRKDC ATM	5.36e-06	2	81	2	21487018
Pubmed	Association between vitamin D status and age-related macular degeneration by genetic risk.	CFH CFI	5.36e-06	2	81	2	26312598
Pubmed	Mutations in NRXN1 and NRXN2 in a patient with early-onset epileptic encephalopathy and respiratory depression.	NRXN1 NRXN2	5.36e-06	2	81	2	30709877
Pubmed	Activation of DNA Damage Response Pathways during Lytic Replication of KSHV.	PRKDC ATM	5.36e-06	2	81	2	26057167
Pubmed	ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin.	TRIM28 ATM	5.36e-06	2	81	2	18657500
Pubmed	Defective ATM-Kap-1-mediated chromatin remodeling impairs DNA repair and accelerates senescence in progeria mouse model.	TRIM28 ATM	5.36e-06	2	81	2	23173799
Pubmed	Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex.	ARFGEF2 ARFGEF1	5.36e-06	2	81	2	23918382
Pubmed	ATM, KAP1 and the Epstein-Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication.	TRIM28 ATM	5.36e-06	2	81	2	37852757
Pubmed	Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma.	ARFGEF2 ARFGEF1	5.36e-06	2	81	2	17360629
Pubmed	Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex.	ARFGEF2 ARFGEF1	5.36e-06	2	81	2	10716990
Pubmed	DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.	PRKDC ATM	5.36e-06	2	81	2	19071136
Pubmed	Use of time-resolved FRET to validate crystal structure of complement regulatory complex between C3b and factor H (N terminus).	CFH CFI	5.36e-06	2	81	2	21936007
Pubmed	Roles of DNA-dependent protein kinase and ATM in cell-cycle-dependent radiation sensitivity in human cells.	PRKDC ATM	5.36e-06	2	81	2	12065055
Pubmed	Membrane association of the Arabidopsis ARF exchange factor GNOM involves interaction of conserved domains.	ARFGEF2 ARFGEF1	5.36e-06	2	81	2	18203920
Pubmed	Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.	PRKDC ATM	5.36e-06	2	81	2	17189255
Pubmed	Sumoylation of Smad3 stimulates its nuclear export during PIASy-mediated suppression of TGF-beta signaling.	PIAS4 SMAD3	5.36e-06	2	81	2	18384750
Pubmed	AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation.	PRKDC ATM	5.36e-06	2	81	2	22972376
Pubmed	G(2)-M phase-correlative bystander effects are co-mediated by DNA-PKcs and ATM after carbon ion irradiation.	PRKDC ATM	5.36e-06	2	81	2	26774662
Pubmed	Functional role of Zic2 phosphorylation in transcriptional regulation.	ZIC2 DHX9	5.36e-06	2	81	2	18068128
Pubmed	Heterozygous deletion of α-neurexin I or α-neurexin II results in behaviors relevant to autism and schizophrenia.	NRXN1 NRXN2	5.36e-06	2	81	2	26595880
Pubmed	ZIC2-dependent transcriptional regulation is mediated by DNA-dependent protein kinase, poly(ADP-ribose) polymerase, and RNA helicase A.	ZIC2 DHX9	5.36e-06	2	81	2	17251188
Pubmed	Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes.	ARFGEF2 ARFGEF1	5.36e-06	2	81	2	18417613
Pubmed	Sensing of ionizing radiation-induced DNA damage by ATM through interaction with histone deacetylase.	ATM HDAC1	5.36e-06	2	81	2	10531300
Pubmed	DNA-PKcs and ATM modulate mitochondrial ADP-ATP exchange as an oxidative stress checkpoint mechanism.	PRKDC ATM	5.36e-06	2	81	2	36727301
Pubmed	ZNF354C is a transcriptional repressor that inhibits endothelial angiogenic sprouting.	TRIM28 ZNF354C	5.36e-06	2	81	2	33154469
Pubmed	Generation of Dhx9-deficient clones in T-cell development with a mitotic recombination technique.	PTPRC DHX9	5.36e-06	2	81	2	22988576
Pubmed	Deciphering the role of distinct DNA-PK phosphorylations at collapsed replication forks.	PRKDC ATM	5.36e-06	2	81	2	32674014
Pubmed	Targeted disruption of TGF-beta-Smad3 signaling leads to enhanced neointimal hyperplasia with diminished matrix deposition in response to vascular injury.	PTPRC SMAD3	5.36e-06	2	81	2	15790953
Pubmed	Smad3-deficient CD11b(+)Gr1(+) myeloid-derived suppressor cells prevent allograft rejection via the nitric oxide pathway.	PRKDC SMAD3	5.36e-06	2	81	2	23045614
Pubmed	A Mechanism-Based Targeted Screen To Identify Epstein-Barr Virus-Directed Antiviral Agents.	TRIM28 ATM	5.36e-06	2	81	2	32796077
Pubmed	Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression.	TRIM28 ATM	5.36e-06	2	81	2	17942393
Pubmed	Ataxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions.	PRKDC ATM	5.36e-06	2	81	2	21245310
Pubmed	The molecular causes of low ATM protein expression in breast carcinoma; promoter methylation and levels of the catalytic subunit of DNA-dependent protein kinase.	PRKDC ATM	5.36e-06	2	81	2	17593081
Pubmed	Chloroquine triggers Epstein-Barr virus replication through phosphorylation of KAP1/TRIM28 in Burkitt lymphoma cells.	TRIM28 ATM	5.36e-06	2	81	2	28249048
Pubmed	Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation.	PRKDC ATM	5.36e-06	2	81	2	20617180
Pubmed	Regulatory components of the alternative complement pathway in endothelial cell cytoplasm, factor H and factor I, are not packaged in Weibel-Palade bodies.	CFH CFI	5.36e-06	2	81	2	25803806
Pubmed	Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin.	NRXN1 NRXN2	5.36e-06	2	81	2	1621094
Pubmed	DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells.	PRKDC ATM	5.36e-06	2	81	2	18172300
Pubmed	Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.	ARFGEF2 ARFGEF1	5.36e-06	2	81	2	10212200
Pubmed	Successful differentiation to T cells, but unsuccessful B-cell generation, from B-cell-derived induced pluripotent stem cells.	PTPRC PRKDC	5.36e-06	2	81	2	21135032
Pubmed	TRIM28 functions as the SUMO E3 ligase for PCNA in prevention of transcription induced DNA breaks.	TRIM28 POLR2B PIAS2	5.43e-06	15	81	3	32900933
Pubmed	Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages.	PSMC3IP PRKDC ATM	5.43e-06	15	81	3	17010969
Pubmed	DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.	TRIM28 PRKDC ATM	6.67e-06	16	81	3	28123024
Pubmed	Proteomic analysis of DZIP3 interactome and its role in proliferation and metastasis in gastric cancer cells.	TRIM28 PRKDC SMAD3 HDAC1	7.33e-06	53	81	4	36841324
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	NPM1 DNAJC13 POLR1A PRKDC NDUFA10 DHX9	8.05e-06	202	81	6	24639526
Pubmed	Interactome of Aiolos/Ikaros Reveals Combination Rationale of Cereblon Modulators with HDAC Inhibitors in DLBCL.	NPM1 TRIM28 HNRNPL HDAC1 DHX9	1.05e-05	123	81	5	35583604
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FBXO38 DNAJC13 PTPRC RPS6KA5 TRIM28 ARFGEF2 PRKDC ATM ANAPC5 DHX9	1.27e-05	774	81	10	15302935
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	PIAS4 NPM1 FBXO38 TRIM28 PRKDC PIAS2 HNRNPL	1.29e-05	332	81	7	32786267
Pubmed	Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.	NRXN1 NRXN2	1.60e-05	3	81	2	38891114
Pubmed	Importin alpha2-interacting proteins with nuclear roles during mammalian spermatogenesis.	PSMC3IP PIAS2	1.60e-05	3	81	2	21900684
Pubmed	Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity.	ARFGEF2 ARFGEF1	1.60e-05	3	81	2	19332778
Pubmed	NSP 5a3a's link to nuclear-cyto proteins B23 and hnRNP-L between normal and aberrant breast cell lines.	NPM1 HNRNPL	1.60e-05	3	81	2	20237420
Pubmed	Specific functions of BIG1 and BIG2 in endomembrane organization.	ARFGEF2 ARFGEF1	1.60e-05	3	81	2	20360857
Pubmed	Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL.	PTPRC HNRNPL	1.60e-05	3	81	2	18669861
Pubmed	Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.	PRKDC ATM	1.60e-05	3	81	2	9766667
Pubmed	Identification and characterization of FUS/TLS as a new target of ATM.	PRKDC ATM	1.60e-05	3	81	2	18620545
Pubmed	Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree.	CFH CFI	1.60e-05	3	81	2	16386793
Pubmed	Ultrastructures and interactions of complement factors H and I.	CFH CFI	1.60e-05	3	81	2	1401896
Pubmed	Severe hypoxia increases expression of ATM and DNA-PKcs and it increases their activities through Src and AMPK signaling pathways.	PRKDC ATM	1.60e-05	3	81	2	30224064
Pubmed	DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks.	PRKDC ATM	1.60e-05	3	81	2	18644470
Pubmed	Tagging single nucleotide polymorphisms in phosphoinositide-3-kinase-related protein kinase genes involved in DNA damage "checkpoints" and lung cancer susceptibility.	PRKDC ATM	1.60e-05	3	81	2	18451257
Pubmed	Altered homeostasis and development of regulatory T cell subsets represent an IL-2R-dependent risk for diabetes in NOD mice.	PTPRC PRKDC	1.60e-05	3	81	2	29259102
Pubmed	AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors.	ARFGEF2 ARFGEF1	1.60e-05	3	81	2	16866877
Pubmed	Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination.	PRKDC ATM	1.60e-05	3	81	2	23836881
Pubmed	DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells.	PRKDC ATM	1.60e-05	3	81	2	27733644
Pubmed	Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities.	PIAS4 PIAS2	1.60e-05	3	81	2	15976810
Pubmed	KAPs off for HIV-1 integration.	TRIM28 HDAC1	1.60e-05	3	81	2	21669392
Pubmed	The TRIM family protein KAP1 inhibits HIV-1 integration.	TRIM28 HDAC1	1.60e-05	3	81	2	21669397
Pubmed	alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.	NRXN1 NRXN2	1.60e-05	3	81	2	16406382
Pubmed	ATM gene variants in patients with idiopathic perifoveal telangiectasia.	CFH ATM	1.60e-05	3	81	2	18502988
Pubmed	Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses.	CFH CFI	1.60e-05	3	81	2	28671664
Pubmed	Dynamic change of histone H2AX phosphorylation independent of ATM and DNA-PK in mouse skin in situ.	PRKDC ATM	1.60e-05	3	81	2	17923115
Pubmed	DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system.	PRKDC ATM	1.60e-05	3	81	2	29101015
Pubmed	Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice.	CALB1 ATM	1.60e-05	3	81	2	10716718
Pubmed	DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells.	PRKDC ATM	1.60e-05	3	81	2	31601897
Pubmed	Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome.	CFH CFI	1.60e-05	3	81	2	17599974
Pubmed	HDAC1-Smad3-mSin3A complex is required for Smad3-induced transcriptional inhibition of hepatocyte growth factor receptor in human lung cancers.	SMAD3 HDAC1	1.60e-05	3	81	2	33151304
Pubmed	Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses.	NRXN1 NRXN2	1.60e-05	3	81	2	31005376
Pubmed	Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy.	PRKDC ATM	1.60e-05	3	81	2	25205036
Pubmed	ATM phosphorylates histone H2AX in response to DNA double-strand breaks.	PRKDC ATM	1.60e-05	3	81	2	11571274
Pubmed	Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase.	PRKDC ATM	1.60e-05	3	81	2	31164689
Pubmed	Tissue-specific DNA-PK-dependent H2AX phosphorylation and gamma-H2AX elimination after X-irradiation in vivo.	PRKDC ATM	1.60e-05	3	81	2	18755145
Pubmed	Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice.	CFH CFI	1.60e-05	3	81	2	18202746
Pubmed	Involvement of BIG1 and BIG2 in regulating VEGF expression and angiogenesis.	ARFGEF2 ARFGEF1	1.60e-05	3	81	2	31199673
Interaction	IKZF1 interactions	CUL2 NPM1 LMO1 TRIM28 ANKRD36 PIAS2 HNRNPL HDAC1 DHX9	1.88e-06	288	79	9	int:IKZF1
Interaction	PLAG1 interactions	PIAS4 PIAS2 SMAD3	4.79e-06	9	79	3	int:PLAG1
Interaction	ZBTB16 interactions	CFH EPN1 PIAS2 ANAPC5 HNRNPL SMAD3 HDAC1	8.73e-06	187	79	7	int:ZBTB16
Interaction	ADGRG2 interactions	ARFGEF1 CERS6 ATM	1.24e-05	12	79	3	int:ADGRG2
Interaction	ZEB1 interactions	NPM1 PRKDC ATM USP9Y SMAD3 HDAC1 DHX9	1.35e-05	200	79	7	int:ZEB1
Interaction	ZNF84 interactions	LMO1 TRIM28 HNRNPL	1.61e-05	13	79	3	int:ZNF84
Interaction	MYT1 interactions	NPM1 HNRNPL HDAC1	1.61e-05	13	79	3	int:MYT1
Interaction	METTL3 interactions	PIAS4 CUL2 NPM1 TRIM28 POLR2B PRKDC SMAD3 HDAC1	1.67e-05	287	79	8	int:METTL3
Interaction	RELA interactions	PIAS4 CUL2 NPM1 POLR1A RPS6KA5 PRKDC ATM SMAD3 HDAC1 DHX9	1.94e-05	485	79	10	int:RELA
Interaction	NR4A1 interactions	RPS6KA5 TRIM28 ATM PIAS2 HNRNPL SMAD3 HDAC1	1.97e-05	212	79	7	int:NR4A1
Interaction	FPR1 interactions	ARFGEF2 ARFGEF1 PRKDC ATM EPN1 TTK	2.44e-05	147	79	6	int:FPR1
Interaction	ZMIZ1 interactions	TRIM28 HNRNPL SMAD3 HDAC1	2.64e-05	44	79	4	int:ZMIZ1
Interaction	HNRNPC interactions	CUL2 NPM1 PPP2R5D AGO4 TRIM28 SUPV3L1 ZNF57 PRKDC HNRNPL HDAC1 DHX9	3.55e-05	634	79	11	int:HNRNPC
Interaction	CRY1 interactions	NPM1 PPP2R5D TRIM28 PRKDC HNRNPL HDAC1	4.21e-05	162	79	6	int:CRY1
Interaction	PWWP2B interactions	PRKDC HNRNPL HDAC1	4.53e-05	18	79	3	int:PWWP2B
Interaction	CFAP96 interactions	NPM1 USP9Y	4.54e-05	3	79	2	int:CFAP96
Interaction	EXOSC3 interactions	NPM1 DIS3L TRIM28 ARFGEF1 HNRNPL	4.58e-05	100	79	5	int:EXOSC3
Interaction	IRF7 interactions	PIAS4 TRIM28 POLR2B SMAD3 HDAC1	4.58e-05	100	79	5	int:IRF7
Interaction	CHEK2 interactions	PPP2R5D LMO1 TRIM28 PSMC3IP PRKDC ATM DHX9	5.63e-05	250	79	7	int:CHEK2
Interaction	EPAS1 interactions	CUL2 NPM1 TRIM28 PRKDC SMAD3 HDAC1	6.07e-05	173	79	6	int:EPAS1
Interaction	CREB1 interactions	CFH PSME3IP1 RPS6KA5 FEZ1 ATM PIAS2 HDAC1	6.23e-05	254	79	7	int:CREB1
Interaction	RBX1 interactions	CUL2 NPM1 FBXO38 TRIM28 POLR2B PRKDC HNRNPL SMAD3 HDAC1 DHX9	6.33e-05	558	79	10	int:RBX1
Interaction	MAPK14 interactions	NPM1 PTPRC RPS6KA5 ATM NEB PIAS2 SMAD3 HDAC1	7.24e-05	353	79	8	int:MAPK14
Interaction	PLAGL1 interactions	PIAS2 SMAD3 HDAC1	7.33e-05	21	79	3	int:PLAGL1
Interaction	H2BC21 interactions	CUL2 NPM1 DNAJC13 RPS6KA5 POLR2B PRKDC NEB DNAH5 ANAPC5 HDAC1 CFAP46	8.22e-05	696	79	11	int:H2BC21
Interaction	CXXC5 interactions	ATM HNRNPL SMAD3	8.46e-05	22	79	3	int:CXXC5
Interaction	ZNF600 interactions	ZNF600 TRIM28	9.06e-05	4	79	2	int:ZNF600
Interaction	REST interactions	MOK NPM1 CALB1 TRIM28 HNRNPL HDAC1 DHX9	1.00e-04	274	79	7	int:REST
Interaction	ZNF331 interactions	FBXO38 TRIM28 USP9Y HNRNPL	1.09e-04	63	79	4	int:ZNF331
Interaction	RBBP8 interactions	PIAS4 LMO1 PRKDC ATM HDAC1	1.18e-04	122	79	5	int:RBBP8
Interaction	GPR17 interactions	PPP2R5D ARFGEF2 ARFGEF1 CERS6 PRKDC ATM TTK	1.22e-04	283	79	7	int:GPR17
Interaction	SMARCAD1 interactions	TRIM28 PRKDC ANAPC5 HNRNPL HDAC1 DHX9	1.24e-04	197	79	6	int:SMARCAD1
Interaction	ASXL1 interactions	CUL2 NPM1 TRIM28 POLR2B PSMC3IP PRKDC NDUFA10	1.31e-04	286	79	7	int:ASXL1
Interaction	NPY2R interactions	ARFGEF1 PRKDC ATM TTK	1.31e-04	66	79	4	int:NPY2R
Interaction	E2F1 interactions	CUL2 TRIM28 ATM TTK ANAPC5 HDAC1	1.35e-04	200	79	6	int:E2F1
Interaction	CYREN interactions	TRIM28 PRKDC ATM	1.41e-04	26	79	3	int:CYREN
Interaction	SMC3 interactions	CFH CUL2 POLR1A FEZ1 TRIM28 PRKDC ATM HDAC1	1.96e-04	408	79	8	int:SMC3
Interaction	ZNF354C interactions	LMO1 TRIM28 ZNF354C	1.97e-04	29	79	3	int:ZNF354C
Interaction	KLF7 interactions	FBXO38 HNRNPL	2.25e-04	6	79	2	int:KLF7
Interaction	ZNF595 interactions	TRIM28 HNRNPL	2.25e-04	6	79	2	int:ZNF595
Interaction	SRP54 interactions	NPM1 TRIM28 PRKDC HNRNPL DHX9	2.32e-04	141	79	5	int:SRP54
Interaction	DNAJC13 interactions	NPM1 DNAJC13 ARFGEF1 HNRNPL HDAC1	2.48e-04	143	79	5	int:DNAJC13
Interaction	E2F3 interactions	CFH TRIM28 HNRNPL HDAC1	2.63e-04	79	79	4	int:E2F3
Interaction	ZFP42 interactions	AGO4 TRIM28 PIAS2	2.91e-04	33	79	3	int:ZFP42
Interaction	CIC interactions	NPM1 TRIM28 POLR2B PRKDC PIAS2 HNRNPL SMAD3 HDAC1 ZIC2 DHX9	2.91e-04	673	79	10	int:CIC
Interaction	TECTA interactions	HNRNPL ZIC2	3.15e-04	7	79	2	int:TECTA
Interaction	ZNF33B interactions	TRIM28 HNRNPL	3.15e-04	7	79	2	int:ZNF33B
Interaction	BRCA1 interactions	PIAS4 CUL2 NPM1 FBXO38 POLR1A TRIM28 ARFGEF2 ARFGEF1 PRKDC ATM HNRNPL SMAD3 HDAC1 DHX9	3.22e-04	1249	79	14	int:BRCA1
Interaction	HIF1A interactions	CUL2 TRIM28 POLR2B PRKDC ATM HNRNPL SMAD3 HDAC1	3.31e-04	441	79	8	int:HIF1A
Interaction	L1TD1 interactions	POLR1A TRIM28 DHX9	3.47e-04	35	79	3	int:L1TD1
Interaction	ZCCHC8 interactions	DIS3L TRIM28 HNRNPL HDAC1 DHX9	3.49e-04	154	79	5	int:ZCCHC8
Interaction	LCOR interactions	CFH ARFGEF2 ATM NDUFA10 HNRNPL HDAC1	3.77e-04	242	79	6	int:LCOR
Interaction	LPAR4 interactions	PRKDC ATM TTK	3.77e-04	36	79	3	int:LPAR4
Interaction	HIC1 interactions	PIAS4 PIAS2 HDAC1	3.77e-04	36	79	3	int:HIC1
Interaction	CCNB1 interactions	MOK TRIM28 PSMC3IP PRKDC EPN1 HDAC1	3.94e-04	244	79	6	int:CCNB1
Interaction	TFE3 interactions	CUL2 NPM1 TRIM28 HNRNPL SMAD3 HDAC1 DHX9	4.02e-04	344	79	7	int:TFE3
Cytoband	1p34	AGO4 INPP5B HDAC1	2.53e-05	32	81	3	1p34
Cytoband	8q13	TRPA1 ARFGEF1	2.01e-04	12	81	2	8q13
Cytoband	15q15.3	GOLM2 PPIP5K1	8.98e-04	25	81	2	15q15.3
GeneFamily	Zinc fingers MIZ-type	PIAS4 PIAS2	1.89e-04	7	55	2	85
Coexpression	PUJANA_BREAST_CANCER_LIT_INT_NETWORK	NPM1 PRKDC ATM SMAD3 HDAC1 DHX9	6.72e-07	101	80	6	M15356
Coexpression	MARSON_BOUND_BY_FOXP3_UNSTIMULATED	MOK PIAS4 PSME3IP1 FBXW10B PTPRC TRPA1 RPS6KA5 SUPV3L1 RNASEK ATM TTK IFIT2 ANAPC5 HNRNPL SMAD3	6.40e-06	1277	80	15	MM1032
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	MOK CUL2 DNAJC13 FAM193A PDE8A BMP2K TRPC1 POLR2B ARFGEF1 CERS6 TTK SMAD3	1.07e-05	856	80	12	M4500
Coexpression	PUJANA_CHEK2_PCC_NETWORK	NPM1 POLR2B PSMC3IP PRKDC ATM PIAS2 TTK ANAPC5 HNRNPL HDAC1 DHX9	1.95e-05	761	80	11	M11961
Coexpression	MARSON_BOUND_BY_FOXP3_UNSTIMULATED	MOK PIAS4 PSME3IP1 PTPRC TRPA1 RPS6KA5 SUPV3L1 RNASEK ATM TTK IFIT2 ANAPC5 HNRNPL SMAD3	2.10e-05	1239	80	14	M1743
Coexpression	ONKEN_UVEAL_MELANOMA_UP	DNAJC13 FAM193A PTPRC FEZ1 ARFGEF2 ARFGEF1 CERS6 PRKDC ATM SMAD3 HDAC1	2.74e-05	790	80	11	M12490
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	CUL2 ZNF600 DNAJC13 PDE8A RPS6KA5 TRPC1 DGKK ESRP1 ARFGEF2 PRKDC ATM CCDC181 TTK	1.11e-05	820	80	13	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP6 CALB1 TRPA1 STXBP5L SCN3A DHX9	8.58e-07	179	80	6	7c8a2fa1326c73dc9e774df645b572864fd97133
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 STXBP5L DGKK MUC5B NEB DNAH5	1.01e-06	184	80	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 STXBP5L DGKK MUC5B NEB DNAH5	1.01e-06	184	80	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 STXBP5L DGKK MUC5B NEB DNAH5	1.01e-06	184	80	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_em\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CFH NPM1 THEM4 SAMD9 PTPRC ANKRD36	1.21e-06	190	80	6	1634a6044dce4e026a63976031a498c7460e3dce
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_em-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CFH NPM1 THEM4 SAMD9 PTPRC ANKRD36	1.21e-06	190	80	6	08813c2f9321b82f0ec66854bb7a383aa1171780
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CFH NPM1 THEM4 SAMD9 PTPRC ANKRD36	1.29e-06	192	80	6	e07b6892276c81c1227e94ca942f6820d89a7ca3
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRPA1 NRXN1 NRXN2 LMO1 TTK HNRNPL	1.37e-06	194	80	6	7a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CFH NPM1 THEM4 SAMD9 PTPRC ANKRD36	1.37e-06	194	80	6	0b0042b6a356a49a059fb64a1e1abb25c82d48cf
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NPM1 THEM4 SAMD9 PTPRC ANKRD36 ATM	1.41e-06	195	80	6	53528e5788083bce5a8d4611ab3808878e6a9cd3
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NPM1 SAMD9 PTPRC ANKRD36 RNASEK ATM	1.54e-06	198	80	6	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CFH SAMD9 PTPRC ANKRD36 ATM	1.64e-05	176	80	5	003076f1a983409ddf31b9c19e61c1facdd72566
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_naive-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NPM1 FBXW10B THEM4 PTPRC ATM	1.69e-05	177	80	5	db6de487ef7976b444afadbf3ac60b3259925566
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALB1 TRPA1 STXBP5L SCN3A DHX9	1.83e-05	180	80	5	8bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NPM1 THEM4 SAMD9 PTPRC ANKRD36	2.25e-05	188	80	5	e5c480b9a030536578f1cc91fb61738f752525b3
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NPM1 THEM4 SAMD9 PTPRC ANKRD36	2.43e-05	191	80	5	c5e22df4a8741b8096cdd1618271fd48d6265846
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NPM1 SAMD9 PTPRC ATM USP9Y	2.55e-05	193	80	5	2901d7a9672a8cf70c9f1c752685b45e4d79ac70
ToppCell	COVID-19_Severe-Lymphoid_T/NK-CD4+_T_activated\|COVID-19_Severe / Disease group, lineage and cell class	NPM1 SAMD9 PTPRC ATM USP9Y	2.55e-05	193	80	5	beb862d38b88572836b0a797c8efef7a2492e0b9
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NPM1 SAMD9 PTPRC ATM USP9Y	2.55e-05	193	80	5	f4310faa13fc8ce99a217e2d1c9cc733683797a1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NPM1 SAMD9 PTPRC ATM USP9Y	2.55e-05	193	80	5	f8af695457d2a0a911a5ac491742465864ebda37
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	NPM1 SAMD9 PTPRC ATM USP9Y	2.55e-05	193	80	5	089aece40130034a89a5213be778f10b0787eeba
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NPM1 SAMD9 PTPRC ANKRD36 ATM	2.62e-05	194	80	5	9588a9b4baebbae08e13d201d4b9dfcf0e6521fb
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	NPM1 THEM4 ANKRD36 ATM USP9Y	2.68e-05	195	80	5	4bdedd924564a260841a9153604026b57487c83d
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MOK MUC5B CCDC181 DNAH5 CFAP46	2.68e-05	195	80	5	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRXN1 STXBP5L SCN3A ANKRD36 CERS6	2.75e-05	196	80	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ZNF600 PTPRC FEZ1 DGKK ATM	2.75e-05	196	80	5	418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF600 PTPRC FEZ1 DGKK ATM	2.75e-05	196	80	5	581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZNF600 PTPRC FEZ1 DGKK ATM	2.75e-05	196	80	5	6beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF600 PTPRC FEZ1 DGKK ATM	2.75e-05	196	80	5	c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCell	proximal-Epithelial-Neuroendocrine\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NRXN1 STXBP5L SCN3A NEB CHRNA2	2.89e-05	198	80	5	5dea6078488d584513c0bdbf5bba54877310b54a
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRXN1 STXBP5L SCN3A ANKRD36 CERS6	2.89e-05	198	80	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Control-CD4+_T\|Control / Disease group and Cell class	CFH NPM1 TRPC1 RNASEK DHX9	2.89e-05	198	80	5	2682eea9b34cfc7e82891c1f1117d3c874107af6
ToppCell	proximal-Epithelial-Neuroendocrine-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NRXN1 STXBP5L SCN3A NEB CHRNA2	2.89e-05	198	80	5	00ccf3020667cf2130bc354b441b65c0b1b0e862
ToppCell	proximal-3-Epithelial-Neuroendocrine\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NRXN1 STXBP5L SCN3A NEB CHRNA2	2.89e-05	198	80	5	a6bc043faf68468d46bac441cf7447c236c7bae4
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Severe / Disease, condition lineage and cell class	NPM1 SAMD9 PTPRC ATM USP9Y	3.03e-05	200	80	5	deeed668b129e66156b5f6abe1a07a9bf842a14d
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T\|COVID-19_Severe / Disease, condition lineage and cell class	ZNF600 PTPRC FEZ1 DGKK ATM	3.03e-05	200	80	5	f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRXN1 STXBP5L SEPTIN14 OR4C12	8.36e-05	128	80	4	91072ca56bce2c552a95edd67e17f43d8cc1de95
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	NRXN1 STXBP5L SEPTIN14 OR4C12	1.15e-04	139	80	4	64c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell	Adult-Immune-enucleated_erythrocyte-D175\|Adult / Lineage, Cell type, age group and donor	BMP6 NRXN1 MCF2 CCDC181	1.62e-04	152	80	4	530d5427d8617dcb223d807b73abee0ef89285f3
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FSIP2 SCN3A MCF2 SMAD3	1.75e-04	155	80	4	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CALB1 IFIT2 CHRNA2 CFAP46	1.84e-04	157	80	4	741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 ESRP1 PSMC3IP NEB	1.93e-04	159	80	4	4000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 ESRP1 PSMC3IP NEB	1.93e-04	159	80	4	7619d0d49738dd08daf01b42664691a5323aa793
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CALB1 CERS6 IFIT2 CHRNA2	2.02e-04	161	80	4	dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCell	IPF-Epithelial-PNEC\|Epithelial / Disease state, Lineage and Cell class	TRPA1 NRXN1 STXBP5L SCN3A	2.07e-04	162	80	4	865d0e215d54fb1412f00cf0649c71c2f1878e57
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THEM4 NRXN1 DNAH5 TTK	2.17e-04	164	80	4	4307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THEM4 NRXN1 DNAH5 TTK	2.17e-04	164	80	4	1d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-RGCs_early_2\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	CALB1 CFI IFIT2 ZIC2	2.22e-04	165	80	4	e460e03992781073cd836a655f15dda3157cea55
ToppCell	droplet-Heart-nan-18m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH NRXN1 ATM ZNF354C	2.27e-04	166	80	4	9adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NPM1 CALB1 SAMD9 ATM	2.38e-04	168	80	4	5e721268f0baa51d3f640f7f4c41db769ebef210
ToppCell	NS-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MOK CCDC181 TTK CFAP46	2.49e-04	170	80	4	f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CALB1 NRXN1 STXBP5L DGKK	2.49e-04	170	80	4	98d13dbd76a826e47d55553f9d11f71c043b573e
ToppCell	ASK454-Immune-NK_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	ZNF600 PTPRC FEZ1 ATM	2.49e-04	170	80	4	84705434234bf2fbb5256bd5a1f6ab54c01c5a51
ToppCell	(7)_MNP-(7)_DC_activated\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	NRXN1 NRXN2 BMP2K CERS6	2.49e-04	170	80	4	4ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC RPS6KA5 CCDC181 TTK	2.54e-04	171	80	4	6e7ade1d14a3ec4c566476aac3eb509bd2661e39
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	PTPRC ANKRD36 ATM ENPEP	2.54e-04	171	80	4	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	FSIP2 SCN3A MUC5B CFI	2.60e-04	172	80	4	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NPM1 SAMD9 PTPRC ANKRD36	2.60e-04	172	80	4	9497948bbe53fb88c6ff6b347f743d456da587e5
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PTPRC BMP2K HNRNPL	2.66e-04	173	80	4	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	droplet-Thymus-nan-3m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN1 NRXN2 LMO1 SCN3A	2.66e-04	173	80	4	63f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PTPRC BMP2K HNRNPL	2.66e-04	173	80	4	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PTPRC BMP2K HNRNPL	2.66e-04	173	80	4	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CFH SAMD9 PTPRC ANKRD36	2.78e-04	175	80	4	cc2428150987911d0d382e8177918724aa69f85c
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH PTPRC BMP2K HNRNPL	2.78e-04	175	80	4	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NPM1 SAMD9 PTPRC ANKRD36	2.96e-04	178	80	4	90dedb3cef9b01907b9f8eec64218d6d2072be1f
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NPM1 SAMD9 PTPRC ANKRD36	2.96e-04	178	80	4	d6312286bf6cc5b107ccd7adb583d9667d4e1d21
ToppCell	Bronchial_Biopsy-Mesenchymal-Smooth_muscle\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	BMP6 NRXN2 SCN3A ENPEP	3.09e-04	180	80	4	7085a851807e6a833965e1366946db0bbc5174e2
ToppCell	Ciliated_cells-A-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	MUC5B CCDC181 DNAH5 CFAP46	3.09e-04	180	80	4	d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_A\|367C / Donor, Lineage, Cell class and subclass (all cells)	ZNF600 PTPRC DGKK ATM	3.09e-04	180	80	4	023c83f0c9d0280983c6fd28ecf04bfa6b1b89e2
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALB1 NRXN2 FEZ1 STXBP5L	3.09e-04	180	80	4	0677bf4a5177d9cbc6716195bd966eeae8de2f31
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SCN3A CERS6 ENPEP	3.22e-04	182	80	4	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SCN3A CERS6 ENPEP	3.22e-04	182	80	4	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	LMO1 CCDC181 DNAH5 CFAP46	3.22e-04	182	80	4	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NPM1 THEM4 SAMD9 ATM	3.43e-04	185	80	4	406b52516b26e9fe2c9e768950af447ec7ad5f3e
ToppCell	MS-matDC\|MS / Condition, Cell_class and T cell subcluster	BMP6 NRXN2 MCF2 ZIC2	3.43e-04	185	80	4	46bd897349598d85e718e25f9a045d2247723c61
ToppCell	MS-matDC-\|MS / Condition, Cell_class and T cell subcluster	BMP6 NRXN2 MCF2 ZIC2	3.43e-04	185	80	4	9fbe70d3a7b106fb31e13b7f95029785f28ca6f4
ToppCell	Ciliated_cells-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	LMO1 CCDC181 DNAH5 CFAP46	3.43e-04	185	80	4	d77ca57b02125a3a57a37f4aed20c89803b7d551
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NPM1 THEM4 SAMD9 ATM	3.43e-04	185	80	4	f2ebd099c8dfcfaca4298bcdd618c50701a9c2c8
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALB1 TRPA1 NRXN2 STXBP5L	3.50e-04	186	80	4	2f103ce2427f9cf2c1fafb6bd6045c5863a47549
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MOK CCDC181 DNAH5 CFAP46	3.50e-04	186	80	4	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NRXN1 STXBP5L SCN3A ZIC2	3.50e-04	186	80	4	c7983281a290201567b398e9ea6baddb96c692bb
ToppCell	Ciliated_cells-B-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	MOK CCDC181 DNAH5 CFAP46	3.57e-04	187	80	4	2b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell	droplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE8A LMO1 CFI IFIT2	3.57e-04	187	80	4	14c239af77116d28d511dea754b6150d20488080
ToppCell	wk_20-22-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SCN3A THSD1 CFI ZIC2	3.57e-04	187	80	4	55aad84b992412e487a32f4970620189a7380ba6
ToppCell	facs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MST1 DGKK CFI	3.60e-04	77	80	3	557f7518e9a89d99f3f2474720deb9cde10e1054
ToppCell	21-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	CALB1 NRXN1 SCN3A NEB	3.64e-04	188	80	4	e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCell	COVID-19_Moderate-NK_activated\|COVID-19_Moderate / disease group, cell group and cell class	TDRD15 SAMD9 FEZ1 DGKK	3.72e-04	189	80	4	8f9f1e71857bed6d59c4b087b6a6970f30fd86be
ToppCell	ASK452-Immune-T_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	PTPRC FEZ1 ANKRD36 USP9Y	3.72e-04	189	80	4	f5dc500f77f04a110dd4a65cf4c03068a495dbdb
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALB1 NRXN2 STXBP5L SCN3A	3.72e-04	189	80	4	fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	MOK CCDC181 DNAH5 CFAP46	3.79e-04	190	80	4	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CALB1 NRXN2 STXBP5L SCN3A	3.79e-04	190	80	4	e792e42fc49472eaf974eb0905819eb51a1da8e5
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	MOK CCDC181 DNAH5 CFAP46	3.79e-04	190	80	4	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MOK ANKRD36 CCDC181 CFAP46	3.79e-04	190	80	4	0adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CALB1 NRXN1 STXBP5L SCN3A	3.79e-04	190	80	4	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	Ciliated_cells-A\|World / lung cells shred on cell class, cell subclass, sample id	MOK CCDC181 DNAH5 CFAP46	3.79e-04	190	80	4	cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCell	facs-Skin-Anagen-3m-Epithelial\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP6 TRIM28 ANAPC5 HNRNPL	3.79e-04	190	80	4	888ded899f0513d41bf655896d59ae8ef74e0978
ToppCell	367C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MOK NPM1 TRPC1 IFIT2	3.79e-04	190	80	4	b7aafb4393d9b9e3e57411c096afb51dab2b0002
ToppCell	BL-critical-LOC-Epithelial-Secretory\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFH ESRP1 MUC5B CFI	3.79e-04	190	80	4	f2abe4bc28e934287e2dcd7b9399d5af78c5c8cf
ToppCell	facs-Skin-Anagen-3m\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP6 TRIM28 ANAPC5 HNRNPL	3.79e-04	190	80	4	3466cebab16964e94da130d0673fa32e7d90b5ed
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CFH NPM1 SAMD9 PTPRC	3.79e-04	190	80	4	f6616b3fe7f4962249503c96c06926240066d861
Disease	Drusen, Radial, Autosomal Dominant	CFH CFI	2.07e-05	3	78	2	C1852021
Disease	Malattia Leventinese	CFH CFI	2.07e-05	3	78	2	C1852020
Disease	tensin-2 measurement	CFH MST1	2.07e-05	3	78	2	EFO_0802122
Disease	DOYNE HONEYCOMB RETINAL DYSTROPHY	CFH CFI	2.07e-05	3	78	2	C1832174
Disease	HELLP Syndrome	CFH CFI	4.12e-05	4	78	2	C0162739
Disease	thrombospondin type-1 domain-containing protein 1 measurement	CFH THSD1	6.86e-05	5	78	2	EFO_0802131
Disease	galectin-7 measurement	CFH MST1	1.03e-04	6	78	2	EFO_0022034
Disease	interleukin-23 receptor measurement	CFH MST1	1.03e-04	6	78	2	EFO_0801725
Disease	r-spondin-3 measurement	CFH MST1	1.44e-04	7	78	2	EFO_0021878
Disease	atypical hemolytic-uremic syndrome (is_implicated_in)	CFH CFI	1.91e-04	8	78	2	DOID:0080301 (is_implicated_in)
Disease	C3 glomerulopathy	CFH CFI	2.45e-04	9	78	2	C4087273
Disease	Atypical hemolytic-uremic syndrome	CFH CFI	2.45e-04	9	78	2	cv:C2931788
Disease	chronic central serous retinopathy	CFH ARFGEF1	2.45e-04	9	78	2	EFO_0009363
Disease	Hemolytic-uremic syndrome	CFH CFI	2.45e-04	9	78	2	cv:C0019061
Disease	Atypical Hemolytic Uremic Syndrome	CFH CFI	3.06e-04	10	78	2	C2931788
Disease	bone morphogenetic protein 7 measurement	CFH BMP6	3.06e-04	10	78	2	EFO_0020187
Disease	hematologic cancer (implicated_via_orthology)	PIAS4 PIAS2	5.28e-04	13	78	2	DOID:2531 (implicated_via_orthology)
Disease	wet macular degeneration	CFH CFI	6.15e-04	14	78	2	EFO_0004683
Disease	C-C motif chemokine 19 measurement	CFH DNAJC13	6.15e-04	14	78	2	EFO_0008047
Disease	mean corpuscular hemoglobin concentration	DNAJC13 SAMD9 AGO4 PTPRC POLR1A BMP2K ARFGEF2 CERS6 PRKDC NEB	6.51e-04	1105	78	10	EFO_0004528
Disease	reading and spelling ability	NRXN1 ARFGEF2 ZNF57 NEB	9.97e-04	166	78	4	EFO_0005301
Disease	Age-related macular degeneration	CFH CFI	1.03e-03	18	78	2	cv:C0242383
Disease	Parkinson's disease (is_implicated_in)	DNAJC13 SEPTIN14 ATM	1.09e-03	76	78	3	DOID:14330 (is_implicated_in)
Disease	glaucoma (is_marker_for)	CFH HDAC1	1.27e-03	20	78	2	DOID:1686 (is_marker_for)
Disease	selenium measurement, response to dietary selenium supplementation	LMO1 DNAH5	1.27e-03	20	78	2	EFO_0006331, EFO_0600021
Disease	Severe Combined Immunodeficiency	PTPRC PRKDC	1.27e-03	20	78	2	C0085110
Disease	X-24309 measurement	DNAJC13 CHRNA2	1.27e-03	20	78	2	EFO_0800872
Disease	Immunologic Deficiency Syndromes	CFH ATM	1.68e-03	23	78	2	C0021051
Disease	birth weight, parental genotype effect measurement	LMO1 SUPV3L1 ARFGEF2 SMAD3	1.70e-03	192	78	4	EFO_0004344, EFO_0005939
Disease	ulcerative colitis	CUL2 MST1 PTPRC DHDDS SMAD3	1.96e-03	335	78	5	EFO_0000729
Disease	atrophic macular degeneration	CFH CFI	1.99e-03	25	78	2	EFO_1001492
Disease	aggressive behavior	SAMD9 ARFGEF2	1.99e-03	25	78	2	EFO_0003015
Disease	FEV change measurement, response to zileuton	NRXN1 CHRNA2	1.99e-03	25	78	2	EFO_0005921, EFO_0007676
Disease	macular degeneration (is_implicated_in)	CFH CFI	2.32e-03	27	78	2	DOID:4448 (is_implicated_in)
Disease	cholesteryl ester 14:0 measurement	CFH SCN3A	2.32e-03	27	78	2	EFO_0010340
Disease	prostate carcinoma in situ (is_marker_for)	ATM HDAC1	2.49e-03	28	78	2	DOID:8634 (is_marker_for)
Disease	retinal degeneration (biomarker_via_orthology)	CFH PTPRC	2.49e-03	28	78	2	DOID:8466 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
DFKQNFDLMKCFQIY	ZNF354C	196	Q86Y25
FFQCVNGKYISQMKA	CFI	226	P05156
MEKFAARYLECNQGQ	ARFGEF1	801	Q9Y6D6
MEKFAARYIECNQGQ	ARFGEF2	746	Q9Y6D5
ENCVTEYMKAINFAK	CFAP46	106	Q8IYW2
DVTFFPFDQQNCKMK	CHRNA2	186	Q15822
MNQKLFDDCTQQYKA	PPP2R5D	476	Q14738
GYNTMEKCIEKQERF	ANKRD36	1706	A6QL64
IYKENERFQYKCNMG	CFH	226	P08603
GQAMECTVAQYFKQK	AGO4	291	Q9HCK5
EKKTCGQRMEEFQRY	ATP4B	6	P51164
EYCRAGQVVNQMNKK	BMP2K	131	Q9NSY1
KKKCLYNFQDAFMEA	FAM193A	591	P78312
KNMKDRYVEVFQCSA	ESRP1	511	Q6NXG1
EQVGKFKMCFNYEIR	MUC5B	2391	Q9HC84
NREQVGKFKMCFNYE	MUC5B	2946	Q9HC84
NREQVGKFKMCFNYE	MUC5B	3646	Q9HC84
QVGKFKMCFNYEIRV	MUC5B	4206	Q9HC84
AKFINYVKNCFRMTD	NPM1	266	P06748
QRFCVGDKFFLKNNM	LMO1	121	P25800
DQKIQFDRAMNDGKY	ANAPC5	511	Q9UJX4
KIRIYNFFNGNCMKV	FBXW10B	636	O95170
RFKEKCVMNNYFGIG	DGKK	851	Q5KSL6
EKKIISFNGCMAQAY	OR4C12	86	Q96R67
GKQKIYFADQDQFDM	PSMC3IP	66	Q9P2W1
EYSKQMQRFNVGEDC	HDAC1	86	Q13547
NFDKNLCFSERYKEM	FSIP2	5006	Q5CZC0
DKCNIFKNMERNDYR	PDE8A	641	O60658
NFMGCLKDVVYKNND	NRXN2	446	Q9P2S2
FDEKLNVCFRNYNAK	FEZ1	66	Q99689
AFNKYKREGFCLQNV	RPS6KA5	721	O75582
DGNYYACKQMKQRFE	MOK	26	Q9UQ07
ENFQKGCQMYLEKYQ	ENPEP	496	Q07075
SNNFMGCLKEVVYKN	NRXN1	431	Q9ULB1
EAMYNQGFIRKQCVD	NDUFA10	171	O95299
NRFDYAQCKKLNMDQ	FBXO38	971	Q6PIJ6
TFKNYFENERNMFGK	CCDC181	171	Q5TID7
YRPNDFSAFQCQKKM	ATM	2791	Q13315
KYEVFMDVCQNFQPV	ATM	2816	Q13315
QKQSTELFQCMYFKD	DIS3L	851	Q8TF46
FRIYKDCVMGSFKNQ	BMP6	256	P22004
AMINKLKQACGYEFT	CUL2	456	Q13617
MCGKEFNKAFELYDQ	CALB1	186	P05937
ANYAKFQKMCDLLFV	CERS6	251	Q6ZMG9
RDNVKIAMDQYGKFN	DNAJC13	681	O75165
RKDDFQMYAKYCQNK	MCF2	581	P10911
RYGNFQLYQMKCEDK	IFIT2	376	P09913
CKENMYAVQTLKDFQ	EPN1	96	Q9Y6I3
NVFCLYGNVEKVKFM	HNRNPL	401	P14866
GYAMKFCEEKEQFRI	GARIN6	206	Q8NEG0
EFCFQNVKYMQLKVE	INPP5B	676	P32019
FQKKDYVRTCIMNNG	MST1	101	P26927
FIMDGNRRYAKKCQV	DHDDS	31	Q86SQ9
RQKFMCEVQVEGYNY	DHX9	31	Q08211
KEYNFLDQRKMDFDQ	DNAH5	521	Q8TE73
QCFDAALYLQMNEKK	PIAS2	366	O75928
KRLEYESFQCGQQMK	GOLM2	156	Q6P4E1
ESFCMEEKQNKFQVY	POLR1A	1301	O95602
ECYRYQKLQKMGFTD	SEPTIN14	306	Q6ZU15
IMKNINKFYDLCEND	TDRD15	511	B5MCY1
FFDNKNELSKRYMVN	SAMD9	1216	Q5K651
QQEYEEQFKFKNMVR	PSME3IP1	66	Q9GZU8
QVMVTLNQEGYKFCK	POLR2B	906	P30876
DYVKNKMRECFQKAF	SCN3A	1016	Q9NY46
QVDGQYFVCNMDDFK	SUPV3L1	541	Q8IYB8
RKNKQFIADNFCMRG	STXBP5L	696	Q9Y2K9
NDYEELARQCKMFAK	TRPC1	256	P48995
CKEAGQIFQQKRNYF	TRPA1	786	O75762
KCQLMKEVQRFGQNY	SAGE2P	536	A6NJ88
FYNDIEKRMVCLFQG	THEM4	126	Q5T1C6
FAFNMKKDEVCVNPY	SMAD3	111	P84022
TIFNCTLFDMGKNKY	THSD1	301	Q9NS62
NGMKCFERFFKAVNC	USP9Y	736	O00507
QCFDAVFYLQMNEKK	PIAS4	346	Q8N2W9
FNNYVDCMKKFLDAL	PRKDC	1736	P78527
YFQMARANCKKFAFV	TTK	131	P33981
EKTYKCEQCRMAFNG	ZNF57	221	Q68EA5
FSFCQVRLNKRKEYM	RNASEK	121	Q6P5S7
QKQEVYMREKSFQCN	ZNF600	151	Q6ZNG1
RFQCGNMIFDNKEIK	PTPRC	341	P08575
ECLKYQMDNAFSQKE	TERB1	21	Q8NA31
CDVNGFSFVKNSMKY	PPIP5K1	331	Q6PFW1
KQQCFSKDIVENYFM	TRIM28	121	Q13263
GAFFRYMRQQCIKQE	ZIC2	241	O95409
VKKNMQDFSDINYRG	NEB	6461	P20929