Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 PSEN1 ERVK-7 ERVK-8 ERVK-19 ERVK-25 SPPL2C	2.38e-08	37	170	7	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 PSEN1 ERVK-7 ERVK-8 ERVK-19 ERVK-25 SPPL2C	2.89e-08	38	170	7	GO:0070001
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	ERVK-6 CHD7 SMARCAD1 ERVK-7 BLM DCLRE1C ERVK-8 MLH1 CHD6 DNTT	8.60e-05	262	170	10	GO:0140097
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-8	9.51e-05	11	170	3	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-8	2.06e-04	14	170	3	GO:0003964
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-8 DNTT	2.99e-04	38	170	4	GO:0034061
GeneOntologyMolecularFunction	lactoperoxidase activity	PXDN PXDNL	4.28e-04	4	170	2	GO:0140825
GeneOntologyMolecularFunction	structural molecule activity	H2BW1 ERVK-6 HSPG2 MXRA5 ABI3BP MAP2 NUMA1 ERVK-7 PXDN ACAN ERVK-8 MACF1 COL14A1 ERVK-19 ERVK-25 NEXN TNXB MYBPC3	6.08e-04	891	170	18	GO:0005198
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-8	7.20e-04	21	170	3	GO:0035613
Pubmed	Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.	PDXDC1 SYCP2L TSHZ3 MYRF DAGLA TNXB	6.00e-09	29	173	6	21829377
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	EPS15 KLF8 TBKBP1 MAP2 NAIP FRYL NCDN PCNX2 PARP10 KMT2C INTS6 ASAP2 USF3 PXDN PTPRN2 ZNF638 MACF1 CHD6 PLCB4 TANC1 ELK4 PALS2 PATJ PRDM15 DAGLA WNK2	2.63e-08	1489	173	26	28611215
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	GTPBP4 ABCF3 CHD7 SMARCAD1 AP3B1 IQGAP1 BLM SART1 TARDBP INTS6 NF1 MLH1 ZNF638 MACF1 HNRNPLL KNL1	4.13e-08	582	173	16	20467437
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RABEP2 GTPBP4 EPS15 HCN1 NUMA1 CNKSR2 CHD7 NCDN IQGAP1 SART1 CCDC88A NF1 PTPRN2 NCAN MACF1 HERC2 ARHGAP21 WNK2 LRRFIP2 FERMT3	8.08e-08	963	173	20	28671696
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HSPG2 CRYBG2 TBKBP1 LMTK2 RAPGEF1 FRYL MDFI ITGA5 PCNX2 KMT2C EIF4ENIF1 SCN5A PXN TANC1 HERC2 MAPKBP1 MYRF ARHGAP21 WNK2 KLHL17 RASD2	1.64e-07	1105	173	21	35748872
Pubmed	A human MAP kinase interactome.	ABI3BP RAPGEF1 MAP3K3 KMT2C ASAP2 USF3 CCDC88A CEP95 MACF1 CHD6 HERC2 PIBF1 WNK2 SOS1	1.71e-07	486	173	14	20936779
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	EPS15 TSHZ3 ERP44 CHD7 PALB2 CCDC88A SALL2 EIF4ENIF1 CEP44 PXN CHD6 ARHGAP21 KNL1	2.01e-07	418	173	13	34709266
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	EPS15 TSHZ3 NUMA1 CNKSR2 CHD7 SMARCAD1 MAGEE1 ASAP2 USF3 EIF4ENIF1 PATJ WNK2 SOS1	2.77e-07	430	173	13	35044719
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	EPS15 NCDN SART1 NF1 PTPRN2 STARD9 ACAN NCAN MACF1 HERC2 DAGLA PBXIP1 ARHGAP21	2.77e-07	430	173	13	32581705
Pubmed	Functional proteomics mapping of a human signaling pathway.	STARD13 HSPG2 EPS15 FAM161B SKIL UBXN11 MACF1 ZNF76 CHD6 MPHOSPH10 HERC2 TOPORS BAG6 KNL1 SMAD6	3.09e-07	591	173	15	15231748
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	MXRA5 ZNF143 GAS2L3 LRRC37A3 MUC16 CHD7 ITGA5 AP3B1 AAAS NF1 PTPRN2 CHD6 MPHOSPH10 CDH17 KNL1	8.06e-07	638	173	15	31182584
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	EPS15 ERP44 FNDC3A HMGCR CHD7 AFAP1L1 AAAS CCDC88A EIF4ENIF1 NSFL1C PHF3 ZNF638 CHD6 TANC1 PATJ KNL1	9.05e-07	733	173	16	34672954
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-19	1.20e-06	5	173	3	12629516
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	TBKBP1 ZNF180 TOPBP1 CHD7 SMARCAD1 BLM CCDC88A SALL2 CEP44 MACF1 TANC1 PATJ TOPORS KNL1	1.64e-06	588	173	14	38580884
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SPATA19 NUMA1 CHD7 SMARCAD1 PALB2 IQGAP1 BLM SART1 NF1 NSFL1C PHF3 ZNF638 TOPORS BAG6 CDH17 SOS1	1.83e-06	774	173	16	15302935
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	AKAP6 FNDC3A CHD7 KMT2C SALL2 PHF3 MACF1 CHD6 DAGLA	2.09e-06	225	173	9	12168954
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AKAP6 ABCF3 ERP44 GAS2L3 LMTK2 FRYL CHD7 AP3B1 NCDN MAP3K3 TARDBP KMT2C ZNF638 MACF1 MPHOSPH10 PATJ NEXN ARHGAP21 BRWD1	2.19e-06	1084	173	19	11544199
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	GTPBP4 TSHZ3 NUMA1 TOPBP1 CHD7 SMARCAD1 BLM PHF3 FAM169A MLH1 CHD6 HERC2 PRDM15 BRWD1	2.42e-06	608	173	14	36089195
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RABEP2 TMEM51 LMTK2 PTPRU ITGA5 AP3B1 BLM TARDBP AAAS CCDC88A PTPRN2 MLH1 ZNF638 PXN TANC1 HERC2 PIBF1 KNL1	5.50e-06	1049	173	18	27880917
Pubmed	Exploring the link between MORF4L1 and risk of breast cancer.	TOPBP1 PALB2 BLM MLH1	5.81e-06	24	173	4	21466675
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CLSTN3 CNKSR2 SMARCAD1 NCDN PXDN PHF3 STARD9 MACF1 CHD6 MAPKBP1 ARHGAP21	6.82e-06	407	173	11	12693553
Pubmed	Direct binding of CRKL to BCR-ABL is not required for BCR-ABL transformation.	RAPGEF1 PXN SOS1	9.94e-06	9	173	3	8978305
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	AKAP6 CNKSR2 FRYL FRMD4A CCDC88A MACF1 SOS1	1.13e-05	151	173	7	17043677
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	STARD13 GTPBP4 ABCF3 NUMA1 CHD7 SMARCAD1 IQGAP1 BLM SART1 TARDBP AAAS NF1 NSFL1C MLH1 ZNF638 MACF1 TANC1 HERC2 NEXN BAG6	1.45e-05	1353	173	20	29467282
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	GTPBP4 GAS2L3 TOPBP1 IQGAP1 CORO1A INTS6 PHF3 ZNF638 MPHOSPH10 HNRNPLL	1.80e-05	370	173	10	22922362
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EPS15 TOPBP1 CHD7 AP3B1 IQGAP1 BLM KMT2C INTS6 PXDN EIF4ENIF1 PHF3 MLH1 PXN MACF1 CHD6 TANC1 MPHOSPH10 HERC2 PATJ HNRNPLL PBXIP1	1.90e-05	1497	173	21	31527615
Pubmed	Dilated Cardiomyopathy Overview	PSEN1 SCN5A NEXN MYBPC3	1.91e-05	32	173	4	20301486
Pubmed	ZNF76 and ZNF143 are two human homologs of the transcriptional activator Staf.	ZNF143 ZNF76	2.46e-05	2	173	2	9705341
Pubmed	Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection.	TOPBP1 SMARCAD1	2.46e-05	2	173	2	28063255
Pubmed	Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1.	BLM MLH1	2.46e-05	2	173	2	11691925
Pubmed	Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.	SCN2A SCN5A	2.46e-05	2	173	2	16847056
Pubmed	A novel exonic rearrangement affecting MLH1 and the contiguous LRRFIP2 is a founder mutation in Portuguese Lynch syndrome families.	MLH1 LRRFIP2	2.46e-05	2	173	2	21785361
Pubmed	Autoantibodies against GLEA2 and PHF3 in glioblastoma: tumor-associated autoantibodies correlated with prolonged survival.	PHF20 PHF3	2.46e-05	2	173	2	15906353
Pubmed	The Bloom's syndrome protein (BLM) interacts with MLH1 but is not required for DNA mismatch repair.	BLM MLH1	2.46e-05	2	173	2	11325959
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	2.46e-05	2	173	2	9060628
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	2.46e-05	2	173	2	9460924
Pubmed	The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1.	HMGCR NF1	2.46e-05	2	173	2	16271875
Pubmed	Transcriptional regulation of the mouse cytosolic chaperonin subunit gene Ccta/t-complex polypeptide 1 by selenocysteine tRNA gene transcription activating factor family zinc finger proteins.	ZNF143 ZNF76	2.46e-05	2	173	2	10893243
Pubmed	Neural progenitor cells do not differentiate prematurely in presenilin-1 null mutant mice.	PSEN1 MAP2	2.46e-05	2	173	2	15519767
Pubmed	TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation.	TOPBP1 BLM	2.46e-05	2	173	2	25794620
Pubmed	Mlh1 deficiency accelerates myeloid leukemogenesis in neurofibromatosis 1 (Nf1) heterozygous mice.	NF1 MLH1	2.46e-05	2	173	2	12881715
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVK-8 ERVK-19	2.57e-05	12	173	3	14557543
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	GTPBP4 NUMA1 FRYL CHD7 IQGAP1 BLM SART1 NF1 PHF3 ZNF638 MACF1 MPHOSPH10 HERC2	2.59e-05	653	173	13	22586326
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	PDXDC1 BLM PHF3 MLH1 PXN MACF1 TANC1 MPHOSPH10 NEXN ARHGAP21 KNL1	2.69e-05	472	173	11	38943005
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAP2 RIMKLA LMTK2 FRYL MAP3K3 CCDC88A NF1 PHF3 CEP95 STARD9 MACF1 TANC1 PATJ PIBF1 ARHGAP21	2.90e-05	861	173	15	36931259
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	PDXDC1 NUMA1 LMTK2 SART1 NF1 ZNF638 HERC2 BAG6 PBXIP1	2.94e-05	313	173	9	38270169
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	STARD13 RABEP2 ZNF143 TBKBP1 AP3B1 MAP3K3 IQGAP1 BLM SART1 CORO1A ASAP2 CCDC88A NF1 EIF4ENIF1 CEP44 ZNF638 PXN COL14A1 PIBF1	3.49e-05	1321	173	19	27173435
Pubmed	Association of gene polymorphisms with chronic kidney disease in Japanese individuals.	ACSS1 PXDN PTPRN2 WNK2	4.25e-05	39	173	4	19724895
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	GTPBP4 ISLR2 SMARCAD1 SKIL SART1 INTS6 ZNF526 SALL2 EIF4ENIF1 SCN5A MLH1 MACF1 TANC1 TOPORS KNL1 SOS1 BRWD1	4.56e-05	1116	173	17	31753913
Pubmed	Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis.	TOPBP1 BLM MLH1	6.46e-05	16	173	3	17696610
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	NUMA1 SART1 PHF3 ZNF638 BRWD1	7.23e-05	86	173	5	37253089
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	HSPG2 MXRA5 PXDN COL14A1 TNXB	7.23e-05	86	173	5	28327460
Pubmed	Glycogen stored in skeletal but not in cardiac muscle in acid alpha-glucosidase mutant (Pompe) mice is highly resistant to transgene-encoded human enzyme.	HMGCR NF1	7.36e-05	3	173	2	12409258
Pubmed	Hypoxia-Associated Factor (HAF) Mediates Neurofibromin Ubiquitination and Degradation Leading to Ras-ERK Pathway Activation in Hypoxia.	SART1 NF1	7.36e-05	3	173	2	30705246
Pubmed	Topographical variation in the distributions of versican, aggrecan and perlecan in the foetal human spine reflects their diverse functional roles in spinal development.	HSPG2 ACAN	7.36e-05	3	173	2	19669783
Pubmed	A kindlin-3-leupaxin-paxillin signaling pathway regulates podosome stability.	PXN FERMT3	7.36e-05	3	173	2	31537712
Pubmed	TDP43 interacts with MLH1 and MSH6 proteins in a DNA damage-inducible manner.	TARDBP MLH1	7.36e-05	3	173	2	38840222
Pubmed	Nanoscale architecture of integrin-based cell adhesions.	ITGA5 PXN	7.36e-05	3	173	2	21107430
Pubmed	The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.	CHD7 CHD6	7.36e-05	3	173	2	28533432
Pubmed	Involvement of beta3A subunit of adaptor protein-3 in intracellular trafficking of receptor-like protein tyrosine phosphatase PCP-2.	PTPRU AP3B1	7.36e-05	3	173	2	17622474
Pubmed	A TNF receptor loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone loss.	TNFSF11 TNFRSF1B	7.36e-05	3	173	2	16680194
Pubmed	Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene.	BLM ACAN	7.36e-05	3	173	2	9808625
Pubmed	Calmodulin mediates Ca2+ sensitivity of sodium channels.	SCN2A SCN5A	7.36e-05	3	173	2	15316014
Pubmed	Valosin-containing protein and neurofibromin interact to regulate dendritic spine density.	NF1 NSFL1C	7.36e-05	3	173	2	22105171
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-19	7.36e-05	3	173	2	10516026
Pubmed	CMYA5 is a novel interaction partner of FHL2 in cardiac myocytes.	CMYA5 MYBPC3	7.36e-05	3	173	2	35176204
Pubmed	Screening of Early and Late Onset Alzheimer's Disease Genetic Risk Factors in a Cohort of Dementia Patients from Liguria, Italy.	PSEN1 TARDBP	7.36e-05	3	173	2	26159191
Pubmed	HERC2 inactivation abrogates nucleolar localization of RecQ helicases BLM and WRN.	BLM HERC2	7.36e-05	3	173	2	33432007
Pubmed	Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain.	PSEN1 TNFRSF1B	7.36e-05	3	173	2	21835156
Pubmed	SMARCAD1-mediated recruitment of the DNA mismatch repair protein MutLα to MutSα on damaged chromatin induces apoptosis in human cells.	SMARCAD1 MLH1	7.36e-05	3	173	2	31843968
Pubmed	Aberrant hippocampal Ca2+ microwaves following synapsin-dependent adeno-associated viral expression of Ca2+ indicators.	SCN2A SLC17A7	7.36e-05	3	173	2	39042440
Pubmed	Evidence that genetic deletion of the TNF receptor p60 or p80 in macrophages modulates RANKL-induced signaling.	TNFSF11 TNFRSF1B	7.36e-05	3	173	2	15315973
Pubmed	Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.	AKAP6 ITGA5 SALL2 NF1 PLCB4 NEXN	7.51e-05	140	173	6	26930384
Pubmed	Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors.	TBKBP1 KBTBD6 NUMA1 TOPBP1 CNKSR2 NF1 ZNF638 PXN BAG6	8.45e-05	359	173	9	35559673
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	CNKSR2 NCDN IQGAP1 ASAP2 NF1 PHF3 NCAN MACF1	8.80e-05	281	173	8	28706196
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	NUMA1 CHD7 BLM SART1 TARDBP NSFL1C PHF3 ZNF638	9.24e-05	283	173	8	30585729
Pubmed	Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs.	HSPG2 ITGA5 ACAN	9.34e-05	18	173	3	12571105
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	A1BG HSPG2 ABI3BP ACAN COL14A1 TNXB	9.47e-05	146	173	6	27068509
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-8 ERVK-19 ERVK-25	1.10e-04	94	173	5	21542922
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	PDXDC1 EPS15 ABCF3 TMEM51 IQGAP1 NSFL1C PXN MACF1 TANC1 PATJ ARHGAP21	1.33e-04	565	173	11	25468996
Pubmed	KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates.	CENPK KNL1	1.47e-04	4	173	2	18045986
Pubmed	Role of common sarcomeric gene polymorphisms in genetic susceptibility to left ventricular dysfunction.	CMYA5 MYBPC3	1.47e-04	4	173	2	27350668
Pubmed	Interaction of POB1, a downstream molecule of small G protein Ral, with PAG2, a paxillin-binding protein, is involved in cell migration.	ASAP2 PXN	1.47e-04	4	173	2	12149250
Pubmed	Cajal-Retzius cells and subplate neurons differentially express vesicular glutamate transporters 1 and 2 during development of mouse cortex.	MAP2 SLC17A7	1.47e-04	4	173	2	17651422
Pubmed	An in situ hybridization study of perlecan, DMP1, and MEPE in developing condylar cartilage of the fetal mouse mandible and limb bud cartilage.	HSPG2 ACAN	1.47e-04	4	173	2	26428891
Pubmed	Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents.	HSPG2 ITGA5	1.47e-04	4	173	2	21747167
Pubmed	Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha.	BLM MLH1	1.47e-04	4	173	2	11470874
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7	1.47e-04	4	173	2	10469592
Pubmed	Quantitative comparison of CrkL-SH3 binding proteins from embryonic murine brain and liver: Implications for developmental signaling and the quantification of protein species variants in bottom-up proteomics.	RAPGEF1 ASAP2	1.47e-04	4	173	2	25982384
Pubmed	Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.	TNFSF11 NF1	1.47e-04	4	173	2	17053831
Pubmed	Gene replacement-Alzheimer's disease (GR-AD): Modeling the genetics of human dementias in mice.	PSEN1 TARDBP	1.47e-04	4	173	2	38343132
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-19	1.47e-04	4	173	2	7983737
Pubmed	Lecticans: organizers of the brain extracellular matrix.	ACAN NCAN	1.47e-04	4	173	2	10766023
Pubmed	AFAP1L1 promotes gastric cancer progression by interacting with VAV2 to facilitate CDC42-mediated activation of ITGA5 signaling pathway.	ITGA5 AFAP1L1	1.47e-04	4	173	2	36631800
Pubmed	Insight into the roles of helicase motif Ia by characterizing Fanconi anemia group J protein (FANCJ) patient mutations.	TOPBP1 MLH1	1.47e-04	4	173	2	24573678
Pubmed	An Alternative Splicing Program for Mouse Craniofacial Development.	MAP2 NUMA1 LRRFIP2	1.51e-04	21	173	3	33013468
Pubmed	Proteomics characterization of extracellular space components in the human aorta.	HSPG2 ABI3BP ACAN COL14A1 TNXB	1.55e-04	101	173	5	20551380
Pubmed	Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.	ZNF143 CHD7 IQGAP1 SART1 INTS6	1.62e-04	102	173	5	26584622
Pubmed	An empirical framework for binary interactome mapping.	C8orf48 MDFI SALL2 EIF4ENIF1 MLH1 PBXIP1 RASD2	1.67e-04	231	173	7	19060904
Pubmed	An investigation into the human serum "interactome".	PALB2 CEP44 SCN5A FAM169A MACF1 DNTT	1.67e-04	162	173	6	15174051
GeneFamily	Fibronectin type III domain containing	ABI3BP FNDC3A PTPRU CMYA5 COL14A1 TNXB MYBPC3	7.34e-05	160	115	7	555
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	ACAN NCAN	2.39e-04	4	115	2	574
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 MXRA5 PXDN PXDNL NEXN MYBPC3	5.75e-04	161	115	6	593
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	AKAP6 MAP2 CMYA5	8.12e-04	29	115	3	396
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN2A SCN5A	1.40e-03	9	115	2	1203
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	CNKSR2 AFAP1L1 ASAP2 ARHGAP21 FERMT3 SOS1	2.04e-03	206	115	6	682
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	PKD1L2 ACAN NCAN	2.24e-03	41	115	3	1298
GeneFamily	UBX domain containing	UBXN11 NSFL1C	2.99e-03	13	115	2	364
GeneFamily	StAR related lipid transfer domain containing	STARD13 STARD9	3.99e-03	15	115	2	759
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	MIER3 CHD7 CHD6	4.66e-03	53	115	3	532
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM10 PRDM15	5.12e-03	17	115	2	1197
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	KLF8 TSHZ3 ZNF143 IKZF2 ZNF180 ZFY ZNF526 PRDM10 SALL2 ZNF76 PRDM15	6.04e-03	718	115	11	28
Coexpression	PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP	GAS2L3 TOPBP1 SKIL CENPK PRMT6 CEP44 MALSU1 PRDM15 KNL1 BRWD1	5.60e-07	195	168	10	M13736
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	STARD13 EPS15 TOPBP1 FNDC3A FRYL BLM ASAP2 PHF3 FAM169A ZNF638 PALS2 PIBF1 SOS1	1.05e-05	466	168	13	M13522
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	STARD13 EPS15 PHF20 TOPBP1 FNDC3A FRYL AP3B1 BLM ASAP2 PHF3 FAM169A ZNF638 MACF1 PLCB4 PALS2 PIBF1 SMAD6 SOS1	1.05e-05	856	168	18	M4500
Coexpression	NABA_CORE_MATRISOME	VWA3A HSPG2 MXRA5 ABI3BP PXDN PXDNL ACAN NCAN COL14A1 TNXB	1.20e-05	275	168	10	M5884
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	FNDC3A FRYL CHD7 KMT2C PRDM10 NF1 MACF1 SOS1	2.21e-05	180	168	8	M8239
Coexpression	GSE21927_SPLENIC_C26GM_TUMOROUS_VS_BONE_MARROW_MONOCYTES_UP	TBKBP1 MAGEE1 ADARB2 NCDN NF1 PHF3 PBXIP1 RASD2	2.69e-05	185	168	8	M7592
Coexpression	GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP	MIER3 MAP3K3 ZNF638 ELK4 PALS2 PRDM15 PBXIP1 CDH17	4.68e-05	200	168	8	M6447
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2	GTPBP4 EPS15 ZNF143 KIAA0586 TOPBP1 FNDC3A CHD7 AP3B1 CENPK SART1 ASAP2 DCLRE1C MLH1 MACF1 KNL1 SOS1 BRWD1	2.02e-06	564	165	17	Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	GTPBP4 KIAA0586 CHD7 AP3B1 BLM USF3 CCDC88A MPHOSPH10 PIBF1 ARHGAP21 LRRFIP2 KNL1	6.04e-06	311	165	12	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	kidney_adult_RenMedVasc_Tie2_k-means-cluster#4_top-relative-expression-ranked_1000	VWA3A HSPG2 PTPRU ITGA5 MFN1 AFAP1L1 SCN2A PLCB4 TNXB	5.78e-05	220	165	9	gudmap_kidney_adult_RenMedVasc_Tie2_k4_1000
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PDXDC1 IKZF2 LMTK2 MUC16 CMYA5 MACF1 TANC1 PATJ ARHGAP21 WNK2	1.69e-09	179	168	10	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	GABRB1 AKAP6 CMYA5 RNF150 PXDNL SCN5A PATJ NEXN WNK2 MYBPC3	3.85e-09	195	168	10	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 CMYA5 CCDC88A ZNF638 MACF1 COL14A1 ELK4 PIBF1 ARHGAP21	2.42e-08	176	168	9	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GABRB1 AKAP6 CMYA5 RNF150 PXDNL SCN5A NEXN WNK2 MYBPC3	3.55e-08	184	168	9	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	AKAP6 CMYA5 RNF150 SCN5A PATJ NEXN WNK2 LRRFIP2 MYBPC3	4.68e-08	190	168	9	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	AKAP6 CMYA5 RNF150 PXDNL PATJ NEXN WNK2 LRRFIP2 MYBPC3	4.90e-08	191	168	9	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	AT1_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 OVCH2 ABI3BP MAP2 RIMKLA PKDCC PXDN NEXN MYRF	5.12e-08	192	168	9	0444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	AKAP6 CMYA5 RNF150 TANC1 PATJ NEXN WNK2 LRRFIP2 MYBPC3	5.12e-08	192	168	9	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	AKAP6 CMYA5 RNF150 PXDNL SCN5A PATJ NEXN WNK2 MYBPC3	5.85e-08	195	168	9	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Mesothelial-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	MXRA5 ABI3BP PKDCC SCN2A SLC17A7 COL14A1 TSKS NEXN SMAD6	6.97e-08	199	168	9	60a653100aff31f7f96796ff2ec634798bfb4b0d
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 CMYA5 RNF150 PXDNL SCN5A NEXN WNK2 MYBPC3	2.80e-07	170	168	8	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	OVCH2 ABI3BP MAP2 RIMKLA PKDCC FZD6 PATJ MYRF	4.15e-07	179	168	8	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	STARD13 OVCH2 ABI3BP MAP2 PKDCC LMTK2 FZD6 MYRF	4.91e-07	183	168	8	6821dca076318115d360ff426eb1218cfe104063
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	OVCH2 MAP2 RIMKLA PKDCC FZD6 PATJ NEXN MYRF	5.11e-07	184	168	8	561592edc3083fad41b91811151b442207c65dd9
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 CMYA5 RNF150 PXDNL SCN5A NEXN WNK2 MYBPC3	5.33e-07	185	168	8	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	GABRB1 AKAP6 CMYA5 RNF150 SCN5A PATJ WNK2 MYBPC3	5.78e-07	187	168	8	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	OVCH2 MAP2 RIMKLA PKDCC FZD6 TANC1 PATJ MYRF	5.78e-07	187	168	8	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HSPG2 OVCH2 MAP2 PKDCC LMTK2 FZD6 PATJ MYRF	6.02e-07	188	168	8	eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	AKAP6 CMYA5 RNF150 SCN5A PATJ WNK2 LRRFIP2 MYBPC3	6.26e-07	189	168	8	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	AKAP6 VWA3A ABI3BP CNKSR2 CMYA5 ADAMTS12 COL14A1 NEXN	6.26e-07	189	168	8	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 KLHL40 ACSS1 CMYA5 SCN5A SLC17A7 WNK2 MYBPC3	6.26e-07	189	168	8	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 KLHL40 ACSS1 CMYA5 SCN5A SLC17A7 WNK2 MYBPC3	6.26e-07	189	168	8	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 ISLR2 ITGA5 CENPK AFAP1L1 BLM STARD9 KNL1	6.52e-07	190	168	8	31de1727822e9818652946dfb962daee77ffad68
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	GABRB1 AKAP6 CMYA5 RNF150 PATJ NEXN WNK2 MYBPC3	6.52e-07	190	168	8	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	HSPG2 ABI3BP MAP2 RAPGEF1 ITGA5 PLCB4 TNFRSF1B SMAD6	6.52e-07	190	168	8	1519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	AKAP6 CMYA5 RNF150 SCN5A TANC1 NEXN WNK2 MYBPC3	6.78e-07	191	168	8	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	AKAP6 CMYA5 RNF150 PXDNL SCN5A PATJ NEXN MYBPC3	7.34e-07	193	168	8	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	AKAP6 HCN1 CMYA5 PXDNL TANC1 NEXN WNK2 MYBPC3	7.63e-07	194	168	8	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	AKAP6 CMYA5 RNF150 SCN5A TANC1 NEXN WNK2 MYBPC3	7.63e-07	194	168	8	c3535f7cc0076653c72db582047cff053c322397
ToppCell	Epithelial_cells-AT1_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	HSPG2 ABI3BP MAP2 PKDCC CNKSR2 PXDN NEXN MYRF	8.24e-07	196	168	8	6c99d29162848161c1f166a032320f87a5d5a631
ToppCell	AT1-AT2_cells\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 MAP2 RIMKLA PKDCC PXDN PATJ NEXN MYRF	8.89e-07	198	168	8	a5b3617ea2ed4bffba59edcf6284799c2b3bbb29
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	MXRA5 ABI3BP MAP2 PKDCC RNF150 COL14A1 NEXN TNXB	8.89e-07	198	168	8	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ABI3BP HMGCR ADAMTS12 PXDNL MACF1 COL14A1 NEXN TNXB	9.24e-07	199	168	8	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYCP2L TSHZ3 PKDCC CNKSR2 AFAP1L1 ADAMTS12 STARD9 TNXB	9.24e-07	199	168	8	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSHZ3 MXRA5 ABI3BP PKDCC MDFI PXDN COL14A1 NEXN	9.24e-07	199	168	8	da016849b804fbf80edbfa8f8f56c9df8bbf2d51
ToppCell	AT1-AT2_cells-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	MAP2 RIMKLA PKDCC CNKSR2 PTPRU SALL2 MYRF	1.34e-06	145	168	7	cd5de30fd948024e3ad043c9411ce9f2722178b2
ToppCell	AT1_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	MAP2 PKDCC CNKSR2 FZD6 PXDN NEXN MYRF	2.80e-06	162	168	7	ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCell	Healthy_Control-Lymphoid-B-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	NIPAL4 CNKSR2 QRICH2 CORO1A PTPRN2 PXDNL PARM1	2.92e-06	163	168	7	d84bd41b4494c7d5c7f88d511bfe481fb12f079d
ToppCell	Healthy_Control-Lymphoid-B\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	NIPAL4 CNKSR2 QRICH2 CORO1A PTPRN2 PXDNL PARM1	2.92e-06	163	168	7	0f723ec2503afa1b3ebb0754972438ffb6e6179d
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D122\|Adult / Lineage, Cell type, age group and donor	STARD13 ISLR2 TSHZ3 TMEM51 NAIP FRMD4A CORO1A	3.29e-06	166	168	7	be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 MAP2 RIMKLA PKDCC INTS6 NEXN MYRF	3.70e-06	169	168	7	cd16e8462ee09877be962fbd9a3badcb825820b0
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	AKAP6 GAS2L3 CMYA5 RNF150 NEXN FERMT3 MYBPC3	3.85e-06	170	168	7	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 RIMKLA HCN1 CMYA5 SCN5A NEXN MYBPC3	4.16e-06	172	168	7	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 RIMKLA HCN1 CMYA5 SCN5A NEXN MYBPC3	4.16e-06	172	168	7	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AKAP6 NIPAL4 CENPK ADAMTS12 ACAN NEXN PARM1	4.32e-06	173	168	7	5c55e1e27e9e3e77600d378cc87b51cc73907527
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP2 ETFBKMT CENPK PRDM10 DAGLA PARM1 KNL1	4.66e-06	175	168	7	15c69dd5635c9251c535f1e22467712e9667ae92
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HSPG2 ABI3BP MAP2 RAPGEF1 ITGA5 PLCB4 SMAD6	5.40e-06	179	168	7	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	AKAP6 MAP2 HCN1 CNKSR2 PTPRN2 PLCB4 PARM1	5.40e-06	179	168	7	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	RV\|World / Chamber and Cluster_Paper	GABRB1 AKAP6 CMYA5 RNF150 PATJ NEXN MYBPC3	5.81e-06	181	168	7	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GAS2L3 ADARB2 PXDN FAM169A PLCB4 PALS2 PATJ	5.81e-06	181	168	7	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 CMYA5 RNF150 PXDNL SCN5A NEXN MYBPC3	5.81e-06	181	168	7	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GAS2L3 ADARB2 PXDN FAM169A PLCB4 PALS2 PATJ	6.03e-06	182	168	7	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	LPS-IL1RA\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPR84 RAPGEF1 FNDC3A AP3B1 ASAP2 TNFRSF1B SMAD6	6.47e-06	184	168	7	c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	AKAP6 CMYA5 RNF150 PXDNL NEXN LRRFIP2 MYBPC3	6.47e-06	184	168	7	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	AKAP6 CMYA5 RNF150 PATJ NEXN LRRFIP2 MYBPC3	6.71e-06	185	168	7	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 KLHL40 CMYA5 SCN5A SLC17A7 WNK2 MYBPC3	6.95e-06	186	168	7	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 KLHL40 CMYA5 SCN5A SLC17A7 WNK2 MYBPC3	6.95e-06	186	168	7	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	OVCH2 MAP2 PKDCC LMTK2 FZD6 PATJ MYRF	6.95e-06	186	168	7	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	AT1_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 ABI3BP MAP2 PKDCC CNKSR2 PXDN MYRF	7.20e-06	187	168	7	f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCell	facs-Heart-Unknown-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 ACSS1 CMYA5 SCN5A NEXN WNK2 MYBPC3	7.20e-06	187	168	7	c004567767b89f3d89f5c7b28d952f3445957e1e
ToppCell	facs-Heart-Unknown-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 ACSS1 CMYA5 SCN5A NEXN WNK2 MYBPC3	7.20e-06	187	168	7	0ffb988e0da2c7205c3515eca8e9851739bff5c5
ToppCell	facs-Heart-Unknown\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 ACSS1 CMYA5 SCN5A NEXN WNK2 MYBPC3	7.20e-06	187	168	7	362e56426a568423a81e8a30e3ecf99b76135843
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	AKAP6 CMYA5 SCN5A TANC1 NEXN WNK2 MYBPC3	7.45e-06	188	168	7	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	AKAP6 MAP2 MACF1 COL14A1 PLCB4 NEXN PARM1	7.45e-06	188	168	7	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	AKAP6 CMYA5 RNF150 PATJ NEXN WNK2 MYBPC3	7.45e-06	188	168	7	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ISLR2 MXRA5 PHF20 LRRC37A3 ADAMTS12 TNFSF11 CHD6	7.45e-06	188	168	7	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	AKAP6 FNDC3A CMYA5 RNF150 TANC1 NEXN MYBPC3	7.71e-06	189	168	7	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	AKAP6 CMYA5 RNF150 PATJ NEXN WNK2 MYBPC3	7.71e-06	189	168	7	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	AKAP6 FNDC3A CMYA5 RNF150 TANC1 NEXN MYBPC3	7.98e-06	190	168	7	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 CMYA5 RNF150 PXDNL SCN5A NEXN MYBPC3	7.98e-06	190	168	7	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 ABI3BP MAP2 RAPGEF1 PLCB4 TNFRSF1B SMAD6	8.26e-06	191	168	7	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	droplet-Heart-nan-24m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 HCN1 ACSS1 CMYA5 SLC17A7 NEXN MYBPC3	8.55e-06	192	168	7	f6a4e348406a852ace9fb21db8fbdff539217645
ToppCell	droplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 HCN1 ACSS1 CMYA5 SLC17A7 NEXN MYBPC3	8.55e-06	192	168	7	1a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CLSTN3 MAGEE1 PCNX2 PTPRN2 SCN2A FAM169A HERC2	9.14e-06	194	168	7	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ3 ADARB2 ADAMTS12 COL14A1 TANC1 TNXB PARM1	9.46e-06	195	168	7	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ3 ADARB2 ADAMTS12 COL14A1 TANC1 TNXB PARM1	9.46e-06	195	168	7	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 ABI3BP MAP2 ITGA5 AFAP1L1 PLCB4 SMAD6	9.46e-06	195	168	7	77e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCell	AT1_cells\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 ABI3BP MAP2 RIMKLA PKDCC NEXN MYRF	9.46e-06	195	168	7	792d6a49b0a875a00569071183d195287a9925c5
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OVCH2 MDFI CMYA5 RNF150 PLCB4 NEXN WNK2	9.78e-06	196	168	7	a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	MXRA5 ABI3BP PKDCC MDFI PXDNL ACAN COL14A1	9.78e-06	196	168	7	57df2a57b35be9851ac0b1e5731baa53052511f0
ToppCell	metastatic_Lymph_Node-Fibroblasts\|metastatic_Lymph_Node / Location, Cell class and cell subclass	HSPG2 ISLR2 MXRA5 ABI3BP ADAMTS12 COL14A1 TNXB	9.78e-06	196	168	7	275e153347caf94edc0c50021bbab49c8696fecb
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ3 PKDCC ADARB2 ADAMTS12 PXDN COL14A1 PARM1	1.01e-05	197	168	7	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	AT1_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 MAP2 RIMKLA PKDCC CNKSR2 NEXN MYRF	1.01e-05	197	168	7	80d81be244c94c435accb643449b4ce6a3462c7f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP2 HCN1 CNKSR2 FRMD4A PTPRN2 SCN2A PALS2	1.04e-05	198	168	7	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Epithelial_cells-AT1-AT2_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	HSPG2 ABI3BP MAP2 PKDCC PXDN NEXN MYRF	1.04e-05	198	168	7	fbc46b20bcd44f2083170aacbc6f5dd00fba685c
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	HSPG2 ABI3BP MAP2 PKDCC CNKSR2 NEXN MYRF	1.08e-05	199	168	7	5a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	ABI3BP ADAMTS12 PXDNL MACF1 COL14A1 NEXN TNXB	1.08e-05	199	168	7	c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ABI3BP ADAMTS12 PXDNL MACF1 COL14A1 NEXN TNXB	1.08e-05	199	168	7	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MXRA5 ABI3BP PXDNL MACF1 COL14A1 NEXN TNXB	1.08e-05	199	168	7	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	Tracheal-10x3prime_v2-Stromal-Schwann\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 EFCAB5 GAS2L3 MAP2 ADARB2 TANC1 TNFRSF1B	1.08e-05	199	168	7	8dc65662c3ca1db2ba0091332f0658abc0afc5de
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CLSTN3 MXRA5 ABI3BP HMGCR FRMD4A COL14A1 TNXB	1.08e-05	199	168	7	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	AKAP6 ITGA5 PXDN COL14A1 PLCB4 NEXN DNTT	1.08e-05	199	168	7	b1753474152b82a0b811b9878c890a359e14919a
ToppCell	343B-Fibroblasts-Fibroblast-G-\|343B / Donor, Lineage, Cell class and subclass (all cells)	MXRA5 ABI3BP MDFI ADAMTS12 MACF1 NEXN TNXB	1.08e-05	199	168	7	9c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell	Tracheal-10x3prime_v2-Stromal-Schwann-Schwann_nonmyelinating\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 EFCAB5 GAS2L3 MAP2 ADARB2 TANC1 TNFRSF1B	1.08e-05	199	168	7	a92718a3f1153b8d2196fd343ed5bc0ebc98cad7
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYCP2L MAP2 PKDCC CNKSR2 AFAP1L1 ADAMTS12 TNXB	1.08e-05	199	168	7	9c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell	343B-Fibroblasts-Fibroblast-G\|343B / Donor, Lineage, Cell class and subclass (all cells)	MXRA5 ABI3BP MDFI ADAMTS12 MACF1 NEXN TNXB	1.08e-05	199	168	7	f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ABI3BP ADAMTS12 PXDNL MACF1 COL14A1 NEXN TNXB	1.11e-05	200	168	7	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	ABI3BP ADAMTS12 PXDNL MACF1 COL14A1 NEXN TNXB	1.11e-05	200	168	7	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ABI3BP ADAMTS12 PXDNL MACF1 COL14A1 NEXN TNXB	1.11e-05	200	168	7	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ABI3BP ADAMTS12 PXDNL MACF1 COL14A1 NEXN TNXB	1.11e-05	200	168	7	50ca6550998e461ef26dd670351060bd940765a8
Drug	Felodipine [72509-76-3]; Down 200; 10.4uM; MCF7; HT_HG-U133A	RABEP2 AP3B1 PRDM10 FAM169A ZNF638 PXN MACF1 ELK4 MAPKBP1 SMAD6	2.17e-06	196	169	10	5294_DN
Drug	Canavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; HL60; HT_HG-U133A	TBKBP1 NUMA1 ASAP2 NF1 PTPRN2 SCN5A SLC17A7 MYRF BRWD1 MYBPC3	2.60e-06	200	169	10	2141_UP
Disease	docosapentaenoic acid measurement	SYCP2L MYRF DAGLA TNXB	1.43e-05	27	163	4	EFO_0006809
Disease	Hypermetropia	TSHZ3 SPATA19 CHD7 PTPRU PTPRN2 ARHGAP21	2.38e-05	103	163	6	HP_0000540
Disease	Primary dilated cardiomyopathy	PSEN1 SCN5A NEXN MYBPC3	3.66e-05	34	163	4	cv:C0007193
Disease	sexual dimorphism measurement	PDXDC1 PHF20 EFCAB13 FRYL HMGCR AP3B1 MAP3K3 SART1 PARP10 CORO1A NF1 ACAN ZNF638 MACF1 MAPKBP1 PATJ MYRF MYBPC3	4.31e-05	1106	163	18	EFO_0021796
Disease	Osteopetrosis Autosomal Dominant Type 2	TNFSF11 FERMT3	9.07e-05	3	163	2	C3179239
Disease	Congenital Osteopetrosis	TNFSF11 FERMT3	9.07e-05	3	163	2	C3645711
Disease	sick sinus syndrome (implicated_via_orthology)	HCN1 SCN5A	9.07e-05	3	163	2	DOID:13884 (implicated_via_orthology)
Disease	Familial dilated cardiomyopathy	PSEN1 SCN5A NEXN MYBPC3	1.03e-04	44	163	4	C0340427
Disease	PR interval	AKAP6 EFCAB5 HSPG2 EPS15 CRYBG2 HCN1 UBXN11 CEP95 SCN5A MACF1 CHD6	1.03e-04	495	163	11	EFO_0004462
Disease	Cardiomyopathy	PSEN1 SCN5A NEXN MYBPC3	1.33e-04	47	163	4	cv:C0878544
Disease	Omenn Syndrome	CHD7 CORO1A DCLRE1C	1.50e-04	19	163	3	C2700553
Disease	Colorectal Carcinoma	AKAP6 CLSTN3 MAP2 CNKSR2 PTPRU ADARB2 NCDN MFN1 KMT2C NF1 PTPRN2 MLH1 TSKS	1.51e-04	702	163	13	C0009402
Disease	Osteopetrosis	TNFSF11 FERMT3	3.00e-04	5	163	2	C0029454
Disease	antiphospholipid syndrome	SYCP2L PTPRU FRMD4A	3.08e-04	24	163	3	EFO_0002689
Disease	alpha-linolenic acid measurement	PDXDC1 MYRF DAGLA	3.48e-04	25	163	3	EFO_0007759
Disease	bipolar disorder	AKAP6 MAP2 CNKSR2 PALB2 PARP10 ASAP2 STARD9 SCN2A NCAN PALS2 WNK2	3.84e-04	577	163	11	MONDO_0004985
Disease	level of Phosphatidylcholine (18:1_20:3) in blood serum	PDXDC1 NCAN	4.48e-04	6	163	2	OBA_2045103
Disease	neutropenia, response to metamizole, Drug-induced agranulocytosis	STARD13 PTPRU	4.48e-04	6	163	2	EFO_0010971, HP_0012235, MONDO_0001475
Disease	wheezing	AP3B1 USF3 PTPRN2 PLCB4	4.67e-04	65	163	4	EFO_0009715
Disease	FEV/FEC ratio	AKAP6 STARD13 EFCAB5 HSPG2 TSHZ3 MAP2 HCN1 KIAA0586 CNKSR2 AFAP1L1 FRMD4A CORO1A ASAP2 ACAN NEXN TNXB SMAD6	4.75e-04	1228	163	17	EFO_0004713
Disease	omega-3 polyunsaturated fatty acid measurement	PDXDC1 NCAN MYRF DAGLA BRWD1	5.12e-04	118	163	5	EFO_0010119
Disease	Developmental Academic Disorder	PSEN1 NF1 SLC17A7	5.44e-04	29	163	3	C1330966
Disease	Learning Disorders	PSEN1 NF1 SLC17A7	5.44e-04	29	163	3	C0023186
Disease	Learning Disturbance	PSEN1 NF1 SLC17A7	5.44e-04	29	163	3	C0751263
Disease	Adult Learning Disorders	PSEN1 NF1 SLC17A7	5.44e-04	29	163	3	C0751262
Disease	Learning Disabilities	PSEN1 NF1 SLC17A7	5.44e-04	29	163	3	C0751265
Disease	congenital heart disease (implicated_via_orthology)	CHD7 KMT2C CHD6 MYBPC3	5.87e-04	69	163	4	DOID:1682 (implicated_via_orthology)
Disease	Frontotemporal dementia	PSEN1 TARDBP	6.25e-04	7	163	2	C0338451
Disease	CHARGE syndrome (implicated_via_orthology)	CHD7 CHD6	6.25e-04	7	163	2	DOID:0050834 (implicated_via_orthology)
Disease	retinal vasculature measurement	GABRB1 HSPG2 MAP2 ITGA5 ADARB2 FZD6 PXDN HERC2 PATJ KNL1	6.33e-04	517	163	10	EFO_0010554
Disease	Prostatic Neoplasms	ERP44 PON1 LMTK2 CHD7 SMARCAD1 PALB2 KMT2C AAAS MLH1 CHD6 PATJ	6.61e-04	616	163	11	C0033578
Disease	Malignant neoplasm of prostate	ERP44 PON1 LMTK2 CHD7 SMARCAD1 PALB2 KMT2C AAAS MLH1 CHD6 PATJ	6.61e-04	616	163	11	C0376358
Disease	eicosapentaenoic acid measurement	SYCP2L TSHZ3 MYRF	6.64e-04	31	163	3	EFO_0007760
Disease	waist circumference	PDXDC1 OVCH2 MIER3 SMARCAD1 PRMT6 RNF150 CORO1A PXDNL PIBF1	6.67e-04	429	163	9	EFO_0004342
Disease	Cardiomyopathies	PSEN1 SCN5A NEXN SOS1 MYBPC3	7.94e-04	130	163	5	C0878544
Disease	migraine disorder	PHF20 SPATA19 TMEM51 CNKSR2 ADARB2 FRMD4A DCLRE1C MACF1	8.69e-04	357	163	8	MONDO_0005277
Disease	phosphatidylcholine measurement	PDXDC1 SYCP2L CHD7 MACF1 MYRF DAGLA TNXB	1.06e-03	284	163	7	EFO_0010226
Disease	corticobasal degeneration disorder	SPPL2C SOS1	1.06e-03	9	163	2	MONDO_0022308
Disease	level of Phosphatidylcholine (O-18:0_20:4) in blood serum	MYRF DAGLA	1.06e-03	9	163	2	OBA_2045127
Disease	level of Phosphatidylcholine (O-18:1_20:3) in blood serum	PDXDC1 MYRF	1.06e-03	9	163	2	OBA_2045130
Disease	1-stearoyl-2-arachidonoyl-GPC (18:0/20:4) measurement	PDXDC1 MYRF	1.06e-03	9	163	2	EFO_0800271
Disease	Generalized Epilepsy with Febrile Seizures Plus	HCN1 SCN2A	1.06e-03	9	163	2	C3502809
Disease	apolipoprotein B measurement	TBKBP1 PSEN1 ZNF180 EFCAB13 HMGCR IQGAP1 PARP10 NF1 NCAN MYRF BRWD1	1.20e-03	663	163	11	EFO_0004615
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN2A SCN5A	1.33e-03	10	163	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN2A SCN5A	1.33e-03	10	163	2	DOID:0080422 (implicated_via_orthology)
Disease	Asthma, Occupational	HERC2 CDH17	1.33e-03	10	163	2	C0264423
Disease	Bipolar Disorder	GABRB1 MAP2 PON1 PALB2 STARD9 SCN2A NCAN SLC17A7 CDH17	1.40e-03	477	163	9	C0005586
Disease	Lymphoma	PON1 BLM MLH1	1.41e-03	40	163	3	C0024299
Disease	cardiac troponin T measurement	HCN1 PKD1L2 SART1 TARDBP NF1 WNK2	1.41e-03	219	163	6	EFO_0005043
Disease	lysophosphatidylethanolamine measurement	MYRF DAGLA KLHL17	1.51e-03	41	163	3	EFO_0010225
Disease	thrombin generation potential measurement	SYCP2L MYBPC3	1.61e-03	11	163	2	EFO_0005538
Disease	phospholipids:total lipids ratio	PDXDC1 HMGCR NCAN MACF1 MYRF MYBPC3	1.69e-03	227	163	6	EFO_0020946
Disease	cystatin C measurement	GTPBP4 ACSS1 FNDC3A ADARB2 PRMT6 TANC1 SOS1 MYBPC3	1.84e-03	402	163	8	EFO_0004617
Disease	cholesteryl ester 20:5 measurement	SYCP2L MYRF DAGLA	1.86e-03	44	163	3	EFO_0010349
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN2A SCN5A	1.93e-03	12	163	2	DOID:0060170 (implicated_via_orthology)
Disease	linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement	NCAN MYRF	1.93e-03	12	163	2	EFO_0800500
Disease	level of Phosphatidylcholine (O-16:0_20:3) in blood serum	PDXDC1 MYRF	1.93e-03	12	163	2	OBA_2045115
Disease	level of Phosphatidylinositol (18:0_20:3) in blood serum	PDXDC1 DAGLA	1.93e-03	12	163	2	OBA_2045157
Disease	dementia (is_implicated_in)	PON1 HMGCR	1.93e-03	12	163	2	DOID:1307 (is_implicated_in)
Disease	esophagus squamous cell carcinoma (is_implicated_in)	KMT2C MLH1 COL14A1	1.98e-03	45	163	3	DOID:3748 (is_implicated_in)
Disease	colorectal cancer	AKAP6 STARD13 EIF4ENIF1 PTPRN2 MLH1 MACF1 TANC1 HERC2 MYRF SMAD6	2.02e-03	604	163	10	MONDO_0005575
Disease	sciatic neuropathy (biomarker_via_orthology)	MAP2 NF1 SLC17A7 TNFRSF1B	2.25e-03	99	163	4	DOID:11446 (biomarker_via_orthology)
Disease	dihomo-linolenoylcarnitine (C20:3n3 or 6) measurement	PDXDC1 MYRF	2.27e-03	13	163	2	EFO_0800547
Disease	Hyperlipoproteinemia Type IIb	PON1 HMGCR	2.27e-03	13	163	2	C1704417
Disease	cognitive function measurement	GABRB1 AKAP6 EFCAB5 TMEM51 FAM161B CHD7 FRMD4A ASAP2 PTPRN2 SCN2A ZNF638 TNXB ARHGAP21 WNK2 CDH17 SOS1 MYBPC3	2.53e-03	1434	163	17	EFO_0008354
Disease	JT interval	SMARCAD1 RNF150 PXDN SCN5A PXN BRWD1	2.63e-03	248	163	6	EFO_0007885
Disease	ascorbic acid 3-sulfate measurement	RABEP2 CORO1A	2.64e-03	14	163	2	EFO_0800173
Disease	1-stearoyl-2-dihomo-linolenoyl-GPI (18:0/20:3n3 or 6) measurement	PDXDC1 DAGLA	2.64e-03	14	163	2	EFO_0022085
Disease	lysophosphatidylcholine 22:5 measurement	MYRF DAGLA	2.64e-03	14	163	2	EFO_0021462
Disease	omega-6:omega-3 polyunsaturated fatty acid ratio	PDXDC1 MYRF DAGLA	2.68e-03	50	163	3	EFO_0010732
Disease	phosphatidylethanolamine measurement	PDXDC1 SYCP2L CMYA5 MYRF DAGLA	2.80e-03	173	163	5	EFO_0010228
Disease	Leukemia, Myelocytic, Acute	PALB2 BLM KMT2C NF1 PXDN	2.80e-03	173	163	5	C0023467
Disease	fatty acid measurement	PDXDC1 HMGCR NCAN MACF1 MYRF DAGLA FERMT3 BRWD1	3.03e-03	436	163	8	EFO_0005110
Disease	P wave duration	HCN1 SCN5A	3.04e-03	15	163	2	EFO_0005094
Disease	RASopathy	NF1 SOS1	3.04e-03	15	163	2	cv:C5555857
Disease	eosinophil measurement	IKZF2 ACSS1 CHD7 PXDN	3.08e-03	108	163	4	EFO_0803540
Disease	cholesteryl ester measurement	PDXDC1 TBKBP1 EFCAB13 PON1 HMGCR MYRF	3.14e-03	257	163	6	EFO_0010351
Disease	triglycerides to total lipids in very large VLDL percentage	PDXDC1 HMGCR MYRF	3.17e-03	53	163	3	EFO_0022340
Disease	cortical surface area measurement	RABEP2 EFCAB5 MAP2 PKDCC FRYL HMGCR CHD7 SMARCAD1 AFAP1L1 CCDC88A MLH1 MACF1 TNXB ARHGAP21 WNK2 SOS1	3.27e-03	1345	163	16	EFO_0010736
Disease	tonsillectomy risk measurement	PARP10 CORO1A TNFSF11 PXDNL ZNF76 TNXB	3.32e-03	260	163	6	EFO_0007924
Disease	asthma, response to diisocyanate	CMYA5 AP3B1 BLM ASAP2 HERC2 CDH17	3.38e-03	261	163	6	EFO_0006995, MONDO_0004979
Disease	Hyperlipoproteinemia Type IIa	PON1 HMGCR	3.46e-03	16	163	2	C0745103
Disease	filaggrin gene expression measurement	FRMD4A RNF150	3.46e-03	16	163	2	EFO_0020899
Disease	level of Phosphatidylcholine (18:0_20:3) in blood serum	PDXDC1 MYRF	3.46e-03	16	163	2	OBA_2045093
Disease	multiple myeloma	FNDC3A AP3B1 HERC2 SOS1	3.51e-03	112	163	4	EFO_0001378
Disease	free cholesterol to total lipids in large HDL percentage	PDXDC1 PON1 HMGCR	3.70e-03	56	163	3	EFO_0022279
Disease	cholesteryl esters to total lipids in large VLDL percentage	PDXDC1 HMGCR MYRF	3.70e-03	56	163	3	EFO_0022250
Disease	free cholesterol to total lipids in medium VLDL percentage	PDXDC1 HMGCR MYRF	3.89e-03	57	163	3	EFO_0022284
Disease	cholesterol in IDL measurement	PDXDC1 EFCAB13 HMGCR	4.09e-03	58	163	3	EFO_0021899
Disease	prostate carcinoma, type 2 diabetes mellitus	AKAP6 LMTK2 KNL1	4.29e-03	59	163	3	EFO_0001663, MONDO_0005148
Disease	free cholesterol to total lipids in very large VLDL percentage	PDXDC1 HMGCR MYRF	4.29e-03	59	163	3	EFO_0022289
Disease	body weight	GABRB1 AKAP6 PDXDC1 ZNF143 CNKSR2 CHD7 AP3B1 PRMT6 CORO1A USF3 PHF3 ACAN ZNF638 PATJ HNRNPLL	4.38e-03	1261	163	15	EFO_0004338
Disease	left ventricular mass	PDXDC1 MYBPC3	4.38e-03	18	163	2	EFO_0009289
Disease	level of Phosphatidylcholine (15:0_18:2) in blood serum	PDXDC1 DAGLA	4.38e-03	18	163	2	OBA_2045065
Disease	level of Phosphatidylcholine (16:0_22:5) in blood serum	MYRF DAGLA	4.38e-03	18	163	2	OBA_2045079
Disease	Hypercholesterolemia, Familial	PON1 HMGCR	4.38e-03	18	163	2	C0020445
Disease	migraine disorder, type 2 diabetes mellitus	ZNF143 FRYL MAP3K3	4.50e-03	60	163	3	MONDO_0005148, MONDO_0005277
Disease	free cholesterol in IDL measurement	PDXDC1 EFCAB13 HMGCR	4.71e-03	61	163	3	EFO_0022181
Disease	Lewy body dementia (is_marker_for)	MAP2 TARDBP	4.88e-03	19	163	2	DOID:12217 (is_marker_for)
Disease	skin sensitivity to sun	ADAMTS12 HERC2	4.88e-03	19	163	2	EFO_0004795

Protein segments in the cluster

Peptide	Gene	Start	Entry
TSESNLEDSIAVGPI	NAIP	371	Q13075
LSETTIQTPDGEERL	AAAS	381	Q9NRG9
AQELGDTTTLEDPSI	ACSS1	656	Q9NUB1
DTPVIDITLDVESSS	AGBL3	601	Q8NEM8
QVSPAVDSDLTESLD	ERVK-19	286	O71037
QVSPAVDSDLTESLD	ERVK-8	286	Q902F8
PSQSLLTLEGDDVET	CLSTN3	571	Q9BQT9
STSTAVEEPDSLEVL	BAG6	6	P46379
QSEGFPVIETSTLTE	GTPBP4	311	Q9BZE4
DDTPALQSVLESDSV	ABCF3	246	Q9NUQ8
EDNVDISEDTLSPIT	CEP44	181	Q9C0F1
ISEDTLSPITDVNEA	CEP44	186	Q9C0F1
EEPLSLQELDTSSGV	CORO1A	256	P31146
GSEDITTSPQLSKED	CHD7	2376	Q9P2D1
SEPVLTEEDATSLIT	ADAMTS12	1281	P58397
EATELGQEATSTISP	AP3B1	16	O00203
SILGETETEPEEDTS	ISLR2	426	Q6UXK2
GETLTEILETPATSE	IQGAP1	1401	P46940
GLSLPEDIETVTASQ	HSPG2	31	P98160
SPDSVDRVLSEGSEV	QRICH2	991	Q9H0J4
LSPEQEETASLVSTG	RABEP2	256	Q9H5N1
PGITNTEDDDTLSTS	ADARB2	51	Q9NS39
STSSESEPELGEIRD	RIMKLA	346	Q8IXN7
VESEQLTGVPLDDSA	INTS6	181	Q9UL03
GPSSETTSEEQLITQ	H2BW1	31	Q7Z2G1
SVVPSQIFELEDGTS	HNRNPLL	411	Q8WVV9
ASEEGDDSLLITVVP	NEXN	161	Q0ZGT2
PESSLSSEEETAGVE	PTPRN2	431	Q92932
LVDSPGTDVTTELDS	MFN1	176	Q8IWA4
SGDSAPVELILSDET	A1BG	291	P04217
TPSLEQGDTQSELLD	C8orf48	61	Q96LL4
TDTLSREIETGPTNI	MUC16	1611	Q8WXI7
SETTDIEGEPTSSLT	MUC16	4586	Q8WXI7
TEETSTQLPDLGLAI	LRRC37A3	741	O60309
DKGDITTDPTEIQTT	nan	396	O00370
LPDTLVDESVSVTES	KMT2C	1326	Q8NEZ4
PVEDTSNDESSILGT	M1AP	191	Q8TC57
ATEGLSTSVQATPDE	MAGEE1	216	Q9HCI5
DTSVLPDSVEIGLQT	NCDN	506	Q9UBB6
DQEIVTIPDLGSLSS	HERC2	1286	O95714
SLLDTSSVLVTQEPE	HMGCR	421	P04035
SIEIANESGETPLDI	ASAP2	646	O43150
TGSTENLEVPDDIST	CCDC88A	1506	Q3V6T2
SSGPLELSAQETVED	PCNX2	156	A6NKB5
DSEVAVTLIDTSQPG	PCNX2	351	A6NKB5
SSGPEQITLEASSTE	PDXDC1	736	Q6P996
ELVSELQLTDPVSSG	FRYL	1441	O94915
LEIPSDSEESTIESG	KLF8	226	O95600
ISEEGTPVLEEASST	MACF1	1351	O94854
SETINDEDISLLPES	MPHOSPH10	96	O00566
LSPEEEIDSTSDSTG	FAM161B	51	Q96MY7
VTGIDDLEQIPADTT	KNL1	1691	Q8NG31
SPGESEETLRLTESD	LMTK2	886	Q8IWU2
NETSGSEVLTSVSDP	GABRB1	376	P18505
ATLETESGELVPTEL	KLHL40	566	Q2TBA0
IESVDGSDPLATLQT	PRDM10	111	Q9NQV6
VVTEELLTLPSNGES	MIER3	436	Q7Z3K6
ISIESREEEITSPGS	PARM1	81	Q6UWI2
GDEDIVTISQATPSS	NSFL1C	46	Q9UNZ2
EGSSLEEPLIESSEV	IKZF2	76	Q9UKS7
QVSPAVDSDLTESLD	ERVK-7	1046	P63135
DGTTLSLTSPESTEE	FAM170B	16	A6NMN3
SEPVSAATTQTLEGD	GPR84	256	Q9NQS5
SVVSEVDDISIPDLS	LRRFIP2	276	Q9Y608
VETSASGIEDVSELP	ACAN	1496	P16112
TISLAQGTPEELTFE	PKD1L2	471	Q7Z442
TDEDVPSGIAAESLT	PTPRU	481	Q92729
SVESLLDELESSVPS	PXN	216	P49023
VEQTETAELPASDSI	PALB2	836	Q86YC2
LESSLSSSEGEEPVE	ITGA5	121	P08648
ENLTELPSSTGAEEI	PALS2	6	Q9NZW5
PQDTEVLIGTSTTLE	PXDNL	336	A1KZ92
LGQETLTEIQTSPET	FZD6	581	O60353
LEDEDSQVTSTISPL	FRMD4A	551	Q9P2Q2
ESVIEPGTHTESTLE	EFCAB5	541	A4FU69
TGTVNEDSSEIILDP	HCN1	196	O60741
LVSSDSLNVPSEEEV	KLHL17	241	Q6TDP4
ESLSSDPEVLLQIDG	BLM	1251	P54132
EIETPTQISLVDEAS	DCLRE1C	86	Q96SD1
QVSPAVDSDLTESLD	ERVK-25	286	P61570
QVSPAVDSDLTESLD	ERVK-6	286	Q69384
PSSEETIQALETLVS	ELK4	216	P28324
TVESLELDQGLTNPS	CHD6	206	Q8TD26
EASDPVTGQETTLAL	COL14A1	521	Q05707
ELEETLLNTSGPEDS	GAS2L3	186	Q86XJ1
SLINGETDESSVPEL	FNDC3A	291	Q9Y2H6
VVPQDILSEELSSES	CMYA5	3431	Q8N3K9
ILSEELSSESTPEDV	CMYA5	3436	Q8N3K9
LDPDSTTDVGDVTNT	CENPK	6	Q9BS16
EASTESQLVSDPTEG	CRYBG2	731	Q8N1P7
VEQDTDVSGEITLLP	PRMT6	331	Q96LA8
VEDTETLSVSGIPNA	CEP95	236	Q96GE4
PEELGASISVTTDEL	BRWD1	1131	Q9NSI6
DVSITEGSPLNEITS	EFCAB13	291	Q8IY85
ETSTALPQSSLIEVE	FAM169A	581	Q9Y6X4
QGLDSTDLDVPTEAV	MDFI	71	Q99750
PVTTEITSLDTENID	ERP44	26	Q9BS26
ILGIEDDTSSVTPVE	MALSU1	216	Q96EH3
EDSESTEPLSVDGIS	MAPKBP1	1016	O60336
TEPLSVDGISSDLEE	MAPKBP1	1021	O60336
SELPEEVEVTTLAST	DAGLA	566	Q9Y4D2
QVSPAVDSDLTESLD	HERVK_113	286	Q902F9
LLPSGVTDENEVTTA	EPS15	566	P42566
LEENTEVTSSGSLTP	ETFBKMT	51	Q8IXQ9
GSTILTIQATDADEP	CDH17	466	Q12864
PEGEATSVTLVEELS	SALL2	881	Q9Y467
GQSFLTEEEEIPSES	KBTBD6	626	Q86V97
TSINSEGEFIPETSE	MAP3K3	196	Q99759
ESRPSLSLGTITDEE	NUMA1	1941	Q14980
TATLDTGLEEVDPTE	PARP10	551	Q53GL7
VSDLVDTDPLQDTLS	PHF20	346	Q9BVI0
EQEPAVSSDSDISLI	RNF150	401	Q9ULK6
ETAAPSETEETLNTG	HHLA1	271	C9JL84
TSSESVLTDLSEPEV	STARD13	181	Q9Y3M8
GIETSDIADVPSDTS	PLCB4	856	Q15147
DSEDIPDTLTTITEL	PKDCC	221	Q504Y2
TLVDNISVDPETGDL	PON1	266	P27169
VQELSSSILAGEDPE	PSEN1	361	P49768
TETEATNSLITAPGE	SMAD6	301	O43541
IIVSEPSEDEESQGL	SMARCAD1	121	Q9H4L7
IPSDSSTELTQTVLE	SKIL	136	P12757
IEIPSEDDGTVLLST	TARDBP	16	Q13148
FLITSPGSTEDEEQL	DNTT	346	P04053
LETSLGNEVSDTEPL	PRDM15	151	P57071
DLSQTDPGEQTLTIE	OVCH2	111	Q7RTZ1
DTSIVTPLTTLEQGD	NCAN	866	O14594
STTLQESREGLPEEE	SCN5A	36	Q14524
DLDSNPGEDTTEIVT	SPPL2C	571	Q8IUH8
PVAEEETTGSAESTL	TANC1	271	Q9C0D5
ETLELSADGRPVTTQ	SLC17A7	31	Q9P2U7
TVDEGSQTDLTLPTL	STARD9	3731	Q9P2P6
EDGSTPERVASLDTV	IQANK1	256	A8MXQ7
STLDTELTPINGTEE	MRGPRX1	6	Q96LB2
ISEESTLSGQQSEVP	MLH1	691	P40692
LSLTDEEPSTSGEQT	SOS1	186	Q07889
PTSQSETIELTGFDD	EIF4ENIF1	226	Q9NRA8
SIESGPLSDILSDEE	AKAP6	711	Q13023
LADDLQTSSTEEEVP	AFAP1L1	406	Q8TED9
SNDPLSISSEVDVIT	CNKSR2	1006	Q8WXI2
LPITSSDIDVVESEA	SPATA19	21	Q7Z5L4
TGDATIDPDTISALE	ZNF143	171	P52747
ESPQSGSILTEETEV	PBXIP1	66	Q96AQ6
SQSTELLPDATDEEV	RAPGEF1	251	Q13905
SSIEDQSGTEPISSE	PATJ	1341	Q8NI35
EGISTSSLEVVPENL	SYCP2L	686	Q5T4T6
LEELTVTDATPDSLS	TNXB	2306	P22105
SSLESEDISLETTVP	PIBF1	16	Q8WXW3
EDISLETTVPTDDIS	PIBF1	21	Q8WXW3
TLIGTETVTPDEQFT	PXDN	801	Q92626
AGQLLPEGTTTETEI	SCN2A	666	Q99250
GLDETTPTSTRADVE	TMEM51	166	Q9NW97
IDEETSEESLLTPTS	NF1	2746	P21359
LEVVDTSTFGPESNI	PHF3	421	Q92576
VPTTEAELLVSGDEN	RASD2	151	Q96D21
ISAQSILELPTSESE	USF3	231	Q68DE3
ILELPTSESESNVLG	USF3	236	Q68DE3
DPEAESVTLRVTGES	FERMT3	26	Q86UX7
EPTDSTGTDSTVEDL	TSKS	91	Q9UJT2
SASSTTILDEEPIVN	SART1	621	O43290
EVTVPLEDTTVSDSL	TSHZ3	101	Q63HK5
PASEQTVTVEEDLLT	MAP2	141	P11137
LVDNIELASTSSPEE	NIPAL4	381	Q0D2K0
GEEISIEVSNPSLLD	TNFSF11	286	O14788
VEGEDTGSLTIPSQE	ZNF180	56	Q9UJW8
TPELVELSSDSEDLG	TOPORS	491	Q9NS56
TELGETIAIIETSQP	ZNF526	626	Q8TF50
RSQLETPETLLGSTE	TNFRSF1B	431	P20333
QGLTSELETSQPLAE	WNK2	1461	Q9Y3S1
GEELENITDFSSSPT	ABI3BP	766	Q7Z7G0
SLEPEESLDVSETEG	SNX16	276	P57768
LISEGRPVETDSESE	ARHGAP21	1626	Q5T5U3
EDDISILTQEALGPS	TBKBP1	6	A7MCY6
VPDVSTITEEGLFSQ	TOPBP1	541	Q92547
ELEEESTPSIQTETL	ZNF638	1126	Q14966
DPSTLEAVQLEDGST	ZNF76	81	P36508
EEISTEITNGPLISL	VWA3A	371	A6NCI4
SETSEPLTSDIVEGT	KIAA0586	956	Q9BVV6
DLSELVVEGDTQVTP	UBXN11	206	Q5T124
SVVEAEIITDPLTSD	ZFY	156	P08048
EGQESKSITLPDSTL	MXRA5	1086	Q9NR99
GEEVSIRNSPTDTIL	MYBPC3	1016	Q14896
GALEPSNIDTSILEE	MYRF	21	Q9Y2G1