Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	condensed chromosome, centromeric region	AHCTF1 APC CHAMP1 GTF2B SYCP2 SMARCC1 ZW10 KNL1	5.52e-06	193	104	8	GO:0000779
GeneOntologyCellularComponent	chromosome, centromeric region	AHCTF1 APC CHAMP1 GTF2B SYCP2 PKHD1 SMARCC1 ZW10 KNL1	9.84e-06	276	104	9	GO:0000775
GeneOntologyCellularComponent	kinetochore	AHCTF1 APC CHAMP1 GTF2B SMARCC1 ZW10 KNL1	3.40e-05	181	104	7	GO:0000776
GeneOntologyCellularComponent	condensed chromosome	AHCTF1 APC CHAMP1 GTF2B SYCP2 SMARCC1 ZW10 KNL1	1.50e-04	307	104	8	GO:0000793
GeneOntologyCellularComponent	chromosomal region	AHCTF1 APC CHAMP1 GTF2B SYCP2 PKHD1 SMARCC1 ZW10 KNL1	2.54e-04	421	104	9	GO:0098687
Domain	DUF4217	DDX31 DDX18	1.79e-04	4	103	2	PF13959
Domain	DUF4217	DDX31 DDX18	1.79e-04	4	103	2	SM01178
Domain	DUF4217	DDX31 DDX18	1.79e-04	4	103	2	IPR025313
Domain	K_chnl_volt-dep_KCNQ_C	KCNQ5 KCNQ4	2.98e-04	5	103	2	IPR013821
Domain	K_chnl_volt-dep_KCNQ	KCNQ5 KCNQ4	2.98e-04	5	103	2	IPR003937
Domain	KCNQ_channel	KCNQ5 KCNQ4	2.98e-04	5	103	2	PF03520
Domain	DEXDc	DDX59 BRIP1 DDX31 DDX18 ERCC6L2	3.43e-04	109	103	5	SM00487
Domain	Helicase_ATP-bd	DDX59 BRIP1 DDX31 DDX18 ERCC6L2	3.58e-04	110	103	5	IPR014001
Domain	Q_MOTIF	DDX59 DDX31 DDX18	1.10e-03	37	103	3	PS51195
Domain	RNA_helicase_DEAD_Q_motif	DDX59 DDX31 DDX18	1.10e-03	37	103	3	IPR014014
Domain	C2-set_2	CADM1 CD22 BTN1A1	1.49e-03	41	103	3	PF08205
Domain	CD80_C2-set	CADM1 CD22 BTN1A1	1.49e-03	41	103	3	IPR013162
Domain	Peptidase_M28	FOLH1 ERMP1	1.92e-03	12	103	2	PF04389
Domain	Peptidase_M28	FOLH1 ERMP1	1.92e-03	12	103	2	IPR007484
Domain	TTL	TTLL7 TTLL6	2.26e-03	13	103	2	PS51221
Domain	TTL/TTLL_fam	TTLL7 TTLL6	2.26e-03	13	103	2	IPR004344
Domain	TTL	TTLL7 TTLL6	2.26e-03	13	103	2	PF03133
Domain	Neurexin-like	CADM1 NRXN3	2.62e-03	14	103	2	IPR003585
Domain	4.1m	CADM1 NRXN3	2.62e-03	14	103	2	SM00294
Domain	Helicase_C	DDX59 DDX31 DDX18 ERCC6L2	2.91e-03	107	103	4	PF00271
Domain	HELICc	DDX59 DDX31 DDX18 ERCC6L2	2.91e-03	107	103	4	SM00490
Domain	Helicase_C	DDX59 DDX31 DDX18 ERCC6L2	3.01e-03	108	103	4	IPR001650
Domain	HELICASE_CTER	DDX59 DDX31 DDX18 ERCC6L2	3.12e-03	109	103	4	PS51194
Domain	HELICASE_ATP_BIND_1	DDX59 DDX31 DDX18 ERCC6L2	3.12e-03	109	103	4	PS51192
Domain	AT_hook	AHCTF1 DOT1L	3.44e-03	16	103	2	PF02178
Pubmed	Differential protein kinase C-dependent modulation of Kv7.4 and Kv7.5 subunits of vascular Kv7 channels.	KCNQ5 KCNQ4 PRKCA	2.60e-08	3	104	3	24297175
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	DDX59 DDX31 GPBP1 APC ZFC3H1 UTP25 AIFM1 DDX18 TBC1D12 SMARCC1 NXF1	9.11e-08	440	104	11	34244565
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGDS ERMP1 ANKRD50 CHAMP1 NRXN3 TECPR2 TET1 PLCB1 ARHGAP20 HPS5 HERC4	5.67e-07	529	104	11	14621295
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	MAGED1 TARS2 HMCES WTAP CUL5 TMX1 STXBP3 AIFM1 EIF3L NXF1 HDLBP	6.22e-07	534	104	11	35032548
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TOR1AIP2 VRK2 DDX31 MAGED1 AHCTF1 ZFC3H1 TARS2 TMX1 URB1 STXBP3 ERAP2 AIFM1 TLN1 DDX18 OSBPL8 MPP7 HDLBP	1.97e-06	1487	104	17	33957083
Pubmed	A human MAP kinase interactome.	RALGDS VRK2 HIVEP1 APC FMNL2 MAP3K5 KIAA1549L ITSN2 PLCB1 HDLBP	2.09e-06	486	104	10	20936779
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RALGDS MAGED1 APC ANKRD50 TARS2 CUL5 PARP4 SMARCC1 OGFOD1 HPS5 NXF1	4.14e-06	650	104	11	38777146
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DDX31 AHCTF1 URB1 UTP25 TLN1 DDX18 EIF3L OSBPL8 SMARCC1 NXF1 HDLBP	4.32e-06	653	104	11	22586326
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	TOR1AIP2 VRK2 MAGED1 AHCTF1 TARS2 TMX1 URB1 STXBP3 TLN1 EIF3L OSBPL8 ZW10 HDLBP	4.90e-06	942	104	13	31073040
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	CARS1 WTAP CD22 TLN1 EIF3L ITSN2 OSBPL8 TCEANC2 SMARCC1 NXF1 HDLBP	8.43e-06	701	104	11	30196744
Pubmed	Bimodal effects of the Kv7 channel activator retigabine on vascular K+ currents.	KCNQ5 KCNQ4	8.86e-06	2	104	2	18536747
Pubmed	Functional PKC in vivo analysis using deficient mouse models.	APC PRKCA	8.86e-06	2	104	2	17956267
Pubmed	Inactivation as a new regulatory mechanism for neuronal Kv7 channels.	KCNQ5 KCNQ4	8.86e-06	2	104	2	17237198
Pubmed	Protein kinase C and cancer: what we know and what we do not.	APC PRKCA	8.86e-06	2	104	2	24336328
Pubmed	Vestibular role of KCNQ4 and KCNQ5 K+ channels revealed by mouse models.	KCNQ5 KCNQ4	8.86e-06	2	104	2	23408425
Pubmed	PKC-dependent regulation of Kv7.5 channels by the bronchoconstrictor histamine in human airway smooth muscle cells.	KCNQ5 PRKCA	8.86e-06	2	104	2	28283479
Pubmed	N-glycosylation Regulates Intrinsic IFN-γ Resistance in Colorectal Cancer: Implications for Immunotherapy.	APC IFNGR2	8.86e-06	2	104	2	36402190
Pubmed	Diet- and Genetically-Induced Obesity Differentially Affect the Fecal Microbiome and Metabolome in Apc1638N Mice.	APC LEPR	8.86e-06	2	104	2	26284788
Pubmed	Structural Determinants of Kv7.5 Potassium Channels That Confer Changes in Phosphatidylinositol 4,5-Bisphosphate (PIP2) Affinity and Signaling Sensitivities in Smooth Muscle Cells.	KCNQ5 KCNQ4	8.86e-06	2	104	2	31871302
Pubmed	Obesity enhances gastrointestinal tumorigenesis in Apc-mutant mice.	APC LEPR	8.86e-06	2	104	2	18725892
Pubmed	Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles.	KCNQ5 KCNQ4	8.86e-06	2	104	2	19389803
Pubmed	Spatiotemporal Regulation of FMNL2 by N-Terminal Myristoylation and C-Terminal Phosphorylation Drives Rapid Filopodia Formation.	FMNL2 PRKCA	8.86e-06	2	104	2	36979484
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	VRK2 DDX31 MAGED1 AHCTF1 APC ERMP1 ZFC3H1 URB1 UTP25 TLN1 EIF3L ITSN2 OSBPL8 NXF1 MPP7 HDLBP	9.52e-06	1497	104	16	31527615
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	MAGED1 APC ZFC3H1 PARP4 URB1 TLN1 DDX18 SMARCC1 ECI2 NXF1 HDLBP	1.14e-05	724	104	11	36232890
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	TOR1AIP2 VRK2 ANKRD50 TMX1 CADM1 STXBP3 OSBPL8 PLCB1 MPP7	1.17e-05	467	104	9	30194290
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	VRK2 BRIP1 CARS1 ANKRD50 CHAMP1 CUL5 STK10 OSBPL8 KNL1	1.27e-05	472	104	9	38943005
Pubmed	HIV-host interactome revealed directly from infected cells.	TOR1AIP2 CUL5 TMX1 ERAP2 AIFM1 OSBPL8	1.36e-05	172	104	6	27375898
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	TARS2 STXBP3 UTP25 AIFM1 TLN1 DDX18 EIF3L OSBPL8 NXF1 HDLBP	1.46e-05	607	104	10	39147351
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ZFC3H1 URB1 NRXN3 TBC1D12 PLCB1	1.65e-05	105	104	5	9628581
Pubmed	Protein kinase Cα signaling regulates inhibitor of DNA binding 1 in the intestinal epithelium.	APC PRKCA	2.65e-05	3	104	2	21454537
Pubmed	Protein kinase C alpha but not PKCzeta suppresses intestinal tumor formation in ApcMin/+ mice.	APC PRKCA	2.65e-05	3	104	2	16849539
Pubmed	Dual inhibition of classical protein kinase C-α and protein kinase C-β isoforms protects against experimental murine diabetic nephropathy.	LEPR PRKCA	2.65e-05	3	104	2	23434935
Pubmed	The FANCJ helicase unfolds DNA-protein crosslinks to promote their repair.	BRIP1 HMCES	2.65e-05	3	104	2	36608669
Pubmed	TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype.	APC TET1	2.65e-05	3	104	2	36764492
Pubmed	Epigenetic Modifications in the Biology of Nonalcoholic Fatty Liver Disease: The Role of DNA Hydroxymethylation and TET Proteins.	HMCES TET1	2.65e-05	3	104	2	26356709
Pubmed	Homomeric and heteromeric assembly of KCNQ (Kv7) K+ channels assayed by total internal reflection fluorescence/fluorescence resonance energy transfer and patch clamp analysis.	KCNQ5 KCNQ4	2.65e-05	3	104	2	18786918
Pubmed	Formin-like 2 Promotes β1-Integrin Trafficking and Invasive Motility Downstream of PKCα.	FMNL2 PRKCA	2.65e-05	3	104	2	26256210
Pubmed	TNF-α up-regulates protein level and cell surface expression of the leptin receptor by stimulating its export via a PKC-dependent mechanism.	LEPR PRKCA	2.65e-05	3	104	2	23070544
Pubmed	Molecular expression and pharmacological identification of a role for K(v)7 channels in murine vascular reactivity.	KCNQ5 KCNQ4	2.65e-05	3	104	2	17519950
Pubmed	ASK1 contributes to fibrosis and dysfunction in models of kidney disease.	LEPR MAP3K5	2.65e-05	3	104	2	30024858
Pubmed	Tannic acid activates the Kv7.4 and Kv7.3/7.5 K(+) channels expressed in HEK293 cells and reduces tension in the rat mesenteric arteries.	KCNQ5 KCNQ4	2.65e-05	3	104	2	26969140
Pubmed	MicroRNA-191 regulates endometrial cancer cell growth via TET1-mediated epigenetic modulation of APC.	APC TET1	2.65e-05	3	104	2	32003827
Pubmed	In vitro interaction of the human immunodeficiency virus type 1 Tat transactivator and the general transcription factor TFIIB with the cellular protein TAP.	GTF2B NXF1	2.65e-05	3	104	2	7707528
Pubmed	Sex Hormone-Binding Globulin Reduction in Metabolic Disorders May Play a Role in NAFLD Development.	SHBG LEPR	2.65e-05	3	104	2	28359088
Pubmed	Protein kinase C alpha -mediated negative feedback regulation is responsible for the termination of insulin-like growth factor I-induced activation of nuclear phospholipase C beta1 in Swiss 3T3 cells.	PLCB1 PRKCA	2.65e-05	3	104	2	11278470
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	MAGED1 WTAP TMX1 PARP4 AIFM1 EIF3L OSBPL8 SMARCC1 ECI2 NXF1 UTP14C HDLBP	3.44e-05	971	104	12	33306668
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	HIVEP1 APC RUSC1 RABGAP1 CHAMP1 TET1 NXF1 KNL1	3.84e-05	418	104	8	34709266
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	TOR1AIP2 ANKRD50 STK10 STXBP3 ITSN2 OSBPL8 PLCB1 MPP7	4.03e-05	421	104	8	36976175
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	AHCTF1 APC CHAMP1 ERCC8 URB1 AIFM1 TLN1 EIF3L ITSN2 SMARCC1 ZW10 NXF1 KNL1	4.17e-05	1155	104	13	20360068
Pubmed	Tbx2 is a master regulator of inner versus outer hair cell differentiation.	BRIP1 KCNQ4 SLC17A8	4.40e-05	23	104	3	35508658
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	MAGED1 AFF2 KMT2E WTAP STK10 MIA2 TLN1 CAMTA1	4.68e-05	430	104	8	35044719
Pubmed	A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy.	ERAP2 TECPR2	5.29e-05	4	104	2	24957906
Pubmed	Protease-activated receptor-1 activation of endothelial cells induces protein kinase Calpha-dependent phosphorylation of syntaxin 4 and Munc18c: role in signaling p-selectin expression.	STXBP3 PRKCA	5.29e-05	4	104	2	15576373
Pubmed	SHBG-C57BL/ksJ-db/db: A New Mouse Model to Study SHBG Expression and Regulation During Obesity Development.	SHBG LEPR	5.29e-05	4	104	2	26441241
Pubmed	The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis.	LEPR WTAP	5.29e-05	4	104	2	29866655
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	TOR1AIP2 VRK2 AHCTF1 RABGAP1 TMX1 TLN1 OSBPL8 ZW10 HDLBP	5.39e-05	568	104	9	37774976
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	MAGED1 RABGAP1 CHAMP1 WTAP TMX1 CADM1 AIFM1 TLN1 DDX18 SMARCC1 PRKCA NXF1 KNL1 HDLBP	5.75e-05	1367	104	14	32687490
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	URB1 TLN1 OSBPL8 PLCB1 CAMTA1 HPS5	6.14e-05	225	104	6	12168954
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	VRK2 MAGED1 AHCTF1 ZFC3H1 KMT2E CHAMP1 TMX1 CADM1 MIA2 EIF3L OSBPL8 SMARCC1 HERC4	6.30e-05	1203	104	13	29180619
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	HIVEP1 DDX31 MAGED1 APC RABGAP1 DOT1L NXF1 KNL1 HDLBP	7.02e-05	588	104	9	38580884
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	VRK2 BRIP1 MAGED1 APC HMCES TMX1 STXBP3 EIF3L OSBPL8 KNL1	7.16e-05	733	104	10	34672954
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	UNC93A FMNL2 PARP4 URB1 AIFM1 TLN1 EIF3L PKHD1 ARHGAP20 NXF1	7.40e-05	736	104	10	29676528
Pubmed	NOP132 is required for proper nucleolus localization of DEAD-box RNA helicase DDX47.	URB1 DDX18	8.80e-05	5	104	2	16963496
Pubmed	Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.	CADM1 NRXN3	8.80e-05	5	104	2	36709330
Pubmed	Argonaute2 mediates compensatory expansion of the pancreatic β cell.	LEPR CADM1	8.80e-05	5	104	2	24361012
Pubmed	The contribution of Kv7 channels to pregnant mouse and human myometrial contractility.	KCNQ5 KCNQ4	8.80e-05	5	104	2	20132415
Pubmed	Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc.	APC LEPR	8.80e-05	5	104	2	27207656
Pubmed	Dual phosphorylations underlie modulation of unitary KCNQ K(+) channels by Src tyrosine kinase.	KCNQ5 KCNQ4	8.80e-05	5	104	2	15304482
Pubmed	High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.	APC LEPR	8.80e-05	5	104	2	26935695
Pubmed	Cholecystokinin facilitates glutamate release by increasing the number of readily releasable vesicles and releasing probability.	PLCB1 PRKCA	8.80e-05	5	104	2	20392936
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	MAGED1 APC TARS2 PRKCA NXF1 KNL1	9.16e-05	242	104	6	34011540
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TOR1AIP2 AHCTF1 APC ANKRD50 KLHL32 URB1 TET1 SMARCC1 DOT1L CAMTA1 HERC4 UTP14C	9.81e-05	1084	104	12	11544199
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	AHCTF1 CARS1 CHAMP1 STXBP3 DDX18 OSBPL8 NXF1 HDLBP	1.29e-04	498	104	8	36634849
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TOR1AIP2 HIVEP1 MUC16 PARP4 CADM1 ITSN2 PLCB1 SMARCC1 KNL1	1.30e-04	638	104	9	31182584
Pubmed	Novel expression and regulation of voltage-dependent potassium channels in placentas from women with preeclampsia.	KCNQ5 KCNQ4	1.32e-04	6	104	2	21730298
Pubmed	A complex interaction pattern of CIS and SOCS2 with the leptin receptor.	LEPR CUL5	1.32e-04	6	104	2	16684815
Pubmed	MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy.	PLCB1 PRKCA	1.32e-04	6	104	2	27353086
Pubmed	Stretch-activation of angiotensin II type 1a receptors contributes to the myogenic response of mouse mesenteric and renal arteries.	KCNQ5 KCNQ4	1.32e-04	6	104	2	24838176
Pubmed	Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism.	LEPR OSBPL8	1.32e-04	6	104	2	21441927
Pubmed	Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.	LEPR CADM1	1.84e-04	7	104	2	28628102
Pubmed	Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.	TTLL6 IFI44L	1.84e-04	7	104	2	24280982
Pubmed	Down-Regulation of Inpp5e Associated With Abnormal Ciliogenesis During Embryonic Neurodevelopment Under Inositol Deficiency.	PKHD1 PRKCA	1.84e-04	7	104	2	34093381
Pubmed	ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction.	MAP3K5 CUL5	1.84e-04	7	104	2	25901786
Pubmed	Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis.	APC LEPR	1.84e-04	7	104	2	34529935
Pubmed	The deubiquitinating enzyme TNFAIP3 mediates inactivation of hepatic ASK1 and ameliorates nonalcoholic steatohepatitis.	MAP3K5 AIFM1	1.84e-04	7	104	2	29227477
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	MAP3K5 CUL5 CD22 KCNQ4 PRKCA DOT1L	1.87e-04	276	104	6	28319085
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	MAGED1 RUSC1 CUL5 PARP4 TLN1	2.25e-04	182	104	5	31067453
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	DDX31 GPBP1 TARS2 CHAMP1 AIFM1 DDX18 NXF1 HDLBP	2.45e-04	547	104	8	37267103
Pubmed	NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.	NRXN3 PKHD1	2.45e-04	8	104	2	19557197
Pubmed	Tubulin polyglutamylation stimulates spastin-mediated microtubule severing.	TTLL7 TTLL6	2.45e-04	8	104	2	20530212
Pubmed	Induction of the Galpha(q) signaling cascade by the human immunodeficiency virus envelope is required for virus entry.	PLCB1 PRKCA	2.45e-04	8	104	2	18632858
Pubmed	Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation.	ERCC8 EIF3L PRKCA	2.74e-04	42	104	3	34581821
Pubmed	Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.	WTAP URB1 DDX18 NXF1	2.76e-04	104	104	4	26167872
Pubmed	Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.	TOR1AIP2 VRK2 TMX1 TLN1 OSBPL8	2.81e-04	191	104	5	31177093
Pubmed	ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.	TOR1AIP2 VRK2 TMX1 MIA2 OSBPL8 ZW10	2.88e-04	299	104	6	37931956
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	DDX59 CARS1 CHAMP1 GTF2B MIA2 AIFM1 TLN1 DDX18 EIF3L OSBPL8 SMARCC1 ECI2 HDLBP	3.11e-04	1415	104	13	28515276
Pubmed	The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription.	GPBP1 GTF2B	3.14e-04	9	104	2	14612417
Pubmed	Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion.	STXBP3 PRKCA	3.14e-04	9	104	2	10194441
Pubmed	Conserved overlapping gene arrangement, restricted expression, and biochemical activities of DNA polymerase ν (POLN).	BRIP1 POLN	3.14e-04	9	104	2	26269593
Pubmed	CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.	MAGED1 TARS2 CUL5 AIFM1	3.18e-04	108	104	4	30166453
Interaction	SNRNP40 interactions	BRIP1 HIVEP1 DDX31 AHCTF1 ZFC3H1 HMCES URB1 DDX18 ITSN2 SMARCC1 ZNF830 DOT1L NXF1 KNL1 HDLBP	8.30e-07	637	103	15	int:SNRNP40
Interaction	POLR1E interactions	HIVEP1 DDX31 ZFC3H1 URB1 UTP25 DDX18 TET1 PRKCA DOT1L NXF1	1.24e-05	350	103	10	int:POLR1E
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	CADM1 CD22 BTN1A1	3.15e-04	40	60	3	592
GeneFamily	DEAD-box helicases	DDX59 DDX31 DDX18	3.64e-04	42	60	3	499
GeneFamily	Tubulin tyrosine ligase family	TTLL7 TTLL6	9.61e-04	14	60	2	779
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	GPRASP1 RALGDS AFF2 APC RUSC1 KMT2E FMNL2 TTLL7 CADM1 NRXN3 KIAA1549L ERAP2 PRKCA CAMTA1 SPAG17 EPHB1	6.44e-06	1106	103	16	M39071
Coexpression	GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_DN	RALGDS PARP4 KCNQ5 TECPR2 CAMTA1 ZW10 NXF1	1.45e-05	200	103	7	M8558
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	AFF2 APC ANKRD50 NRXN3 OSBPL8 SLC17A8 PDE5A	1.56e-07	169	105	7	c135d7ae0490d0024e0f4bd8c4ad42f6674a61da
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AFF2 HMCES KIAA1549L KCNQ5 CD22 KNL1	1.91e-06	156	105	6	203ef22eb76bd2b829b027c30af0557080f4006c
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 LEPR CADM1 KCNQ5 KCNQ4 PDE5A	4.23e-06	179	105	6	56db12467b445f2b8ef92af50779eeab10413eb2
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BRIP1 DDX31 MAP6D1 TARS2 TET1 PLCB1	4.66e-06	182	105	6	d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BRIP1 DDX31 MAP6D1 TARS2 TET1 PLCB1	4.66e-06	182	105	6	92f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BRIP1 DDX31 MAP6D1 TARS2 TET1 PLCB1	4.66e-06	182	105	6	02baca9a72c7b559c3e452693b3b134af804c868
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AFF2 ENTHD1 TTLL7 CD22 TLN1 BTN1A1	5.78e-06	189	105	6	aba941ba6ce7702418b3f470bde573d123c4aade
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 LEPR CADM1 KCNQ5 KCNQ4 PDE5A	5.78e-06	189	105	6	ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 LEPR TTLL7 CADM1 KCNQ5 PDE5A	5.96e-06	190	105	6	7e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	AFF2 LEPR CADM1 KCNQ5 KCNQ4 PDE5A	5.96e-06	190	105	6	979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 LEPR TTLL7 CADM1 KCNQ5 PDE5A	5.96e-06	190	105	6	7fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	AFF2 LEPR CADM1 KCNQ5 KCNQ4 PDE5A	6.33e-06	192	105	6	063e119c4b58957643908f667e6cfd6f7517fd03
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 CADM1 KCNQ5 KCNQ4 CORIN PDE5A	7.12e-06	196	105	6	6708026bafd19c35c5c4e81911344d36a0f508cd
ToppCell	Control-Myeloid-TRAM3\|Control / Disease group,lineage and cell class （2021.01.30）	IFNGR2 GTF2B TLN1 EDEM2 IFI44L HDLBP	7.33e-06	197	105	6	733ff40039d67e561c2ded7c9bd0b4353101741e
ToppCell	BAL-Control-Myeloid-TRAM-TRAM3\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IFNGR2 GTF2B TLN1 EDEM2 IFI44L HDLBP	7.33e-06	197	105	6	4416efdbd9c4ac3356a5dff2d535c2d7383376a9
ToppCell	BAL-Control-Myeloid-TRAM-TRAM3-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IFNGR2 GTF2B TLN1 EDEM2 IFI44L HDLBP	7.33e-06	197	105	6	0f1c4a328968b32874e6ebb0803e665adcbbc450
ToppCell	BAL-Control-Myeloid-TRAM-TRAM3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IFNGR2 GTF2B TLN1 EDEM2 IFI44L HDLBP	7.33e-06	197	105	6	aafe0cd697b0b7f0756596148e0906443fdf8ef7
ToppCell	BAL-Control-Myeloid-TRAM-TRAM3-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IFNGR2 GTF2B TLN1 EDEM2 IFI44L HDLBP	7.33e-06	197	105	6	e131634bc67e0bd31a938a8e8df8dc752e1d0f47
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRXN3 KIAA1549L KCNQ5 OSBPL8 PLCB1 CORO6	7.55e-06	198	105	6	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	mild-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF555 AFF2 PARP4 SYCP2 OGFOD1 ZW10	7.99e-06	200	105	6	ca0a08bf162c954f037a56aa0cbb8b5d7c6ffec0
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	APC ANKRD50 NRXN3 OSBPL8 CORIN	3.99e-05	161	105	5	b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCell	Healthy_donor-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	GPRASP1 CARS1 ENTHD1 TET1 PRKCA	3.99e-05	161	105	5	8a61395af33132783a0a37956c6f821aba5d3b1e
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AFF2 TTLL7 CADM1 KCNQ5 PDE5A	6.09e-05	176	105	5	e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AFF2 TTLL7 CADM1 KCNQ5 PDE5A	6.09e-05	176	105	5	f931192e3cc65414e2245354f443473696cc7ce8
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KLHL32 MAP3K5 NRXN3 PKHD1 MPP7	6.26e-05	177	105	5	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AFF2 KCNQ4 PLCB1 PRKCA PDE5A	7.32e-05	183	105	5	8a799807fbf24456a9811e0c64068187940a2f71
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AFF2 KCNQ4 PLCB1 PRKCA PDE5A	7.51e-05	184	105	5	689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APC MIA2 TLN1 ITSN2 SMARCC1	7.51e-05	184	105	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AFF2 CADM1 KCNQ4 PLCB1 PDE5A	7.51e-05	184	105	5	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HIVEP1 GPBP1 KMT2E GTF2B CD22	7.71e-05	185	105	5	e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	BRIP1 AFF2 KCNQ5 CD22 KNL1	7.71e-05	185	105	5	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GPRASP1 REP15 PARP4 PDE5A HPS5	7.91e-05	186	105	5	77bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	BRIP1 CADM1 NRXN3 PLCB1 PRKCA	7.91e-05	186	105	5	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	mild-unassigned\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZNF555 AFF2 SYCP2 OGFOD1 ZW10	7.91e-05	186	105	5	5b2e1a58916f392fa1156bf9210df528775248ff
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BRIP1 CADM1 NRXN3 PLCB1 PRKCA	7.91e-05	186	105	5	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	GPRASP1 REP15 PARP4 PDE5A HPS5	7.91e-05	186	105	5	13bc41c60fd628af31899a5e8b480e06cc4781be
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAP3K5 CADM1 NRXN3 PKHD1 MPP7	8.11e-05	187	105	5	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 LEPR CADM1 KCNQ5 PDE5A	8.74e-05	190	105	5	1004e89d99c9d46c78b7d3532d8d4aadb81a96fd
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 LEPR CADM1 KCNQ5 PDE5A	8.74e-05	190	105	5	10b02c62e72bfea9767e3e751011436925da823e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERMP1 LEPR CADM1 PKHD1 PLCB1	8.96e-05	191	105	5	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LEPR CADM1 KCNQ5 PRKCA PDE5A	8.96e-05	191	105	5	2ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP1 GPBP1 ZFC3H1 KMT2E PLCB1	9.18e-05	192	105	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AFF2 ENTHD1 TTLL7 CD22 TLN1	9.18e-05	192	105	5	690cf19e9b0b2ada80097c63eae827529aa5b6f3
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AFF2 ENTHD1 TTLL7 CD22 TLN1	9.18e-05	192	105	5	3d6c4c5847ca1e44fa380403d25af45d5b51ee9b
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 LEPR CADM1 KCNQ5 PDE5A	9.18e-05	192	105	5	158cc5736f154da1cb3186ffbf186eae10483e48
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AFF2 ENTHD1 TTLL7 CD22 TLN1	9.18e-05	192	105	5	e0412964a3ee1bf3c0ef64f9a6f20f7e7835701e
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AFF2 ENTHD1 TTLL7 CD22 TLN1	9.18e-05	192	105	5	b5871247a5f3e970fa05b33fff21bef9d2ab5741
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 LEPR CADM1 KCNQ5 PDE5A	9.18e-05	192	105	5	f4ff62ac9c53eafbe917706de9af8b2d4bded4d4
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP1 GPBP1 ZFC3H1 KMT2E PLCB1	9.41e-05	193	105	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOLH1 MAP6D1 ERMP1 KLHL32 TTLL7	9.64e-05	194	105	5	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 CADM1 KCNQ5 KCNQ4 PDE5A	9.87e-05	195	105	5	4a5d2f62aad5817d077177bf8b4ff0e46d3b8d97
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AFF2 CADM1 KCNQ5 KCNQ4 PDE5A	9.87e-05	195	105	5	7a32a8535c29b819dacba901d0658280a2631c94
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED1 KLHL32 TTLL7 PRKCA PDE5A	9.87e-05	195	105	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	GPRASP1 ZFC3H1 IFNGR2 ERCC6L2 PRKCA	9.87e-05	195	105	5	d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRXN3 KIAA1549L KCNQ5 PLCB1 CORO6	1.01e-04	196	105	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOLH1 MAP6D1 FMNL2 KLHL32 TTLL7	1.04e-04	197	105	5	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 LEPR ARHGAP20 MPP7 HDLBP	1.04e-04	197	105	5	cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRXN3 KIAA1549L KCNQ5 PLCB1 CORO6	1.06e-04	198	105	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NRXN3 KIAA1549L KCNQ5 PLCB1 CORO6	1.06e-04	198	105	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TTLL7 TLN1 PKHD1 NXF1 UTP14C	1.09e-04	199	105	5	174f6013af6eafa577f84205a62927f2b367fda3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOLH1 MAP6D1 FMNL2 KLHL32 TTLL7	1.09e-04	199	105	5	214a6a267e77e5508867b9eb48c4fbc7855ed0a0
ToppCell	Bronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	AFF2 CADM1 KCNQ4 PLCB1 PDE5A	1.11e-04	200	105	5	12326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	NRXN3 KIAA1549L KCNQ5 PLCB1 CORO6	1.11e-04	200	105	5	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOLH1 MAP6D1 FMNL2 KLHL32 TTLL7	1.11e-04	200	105	5	091a18d6efed81cab99955c3047f172170f70476
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOLH1 MAP6D1 FMNL2 KLHL32 TTLL7	1.11e-04	200	105	5	3b8513defe25262ab4b492345b2628570eaefd17
ToppCell	Bronchial-10x5prime-Stromal-Pericyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	AFF2 CADM1 KCNQ4 PLCB1 PDE5A	1.11e-04	200	105	5	362706445edb33b313684efe50b1f44f5f816e67
Disease	N-acetylglucosaminylasparagine measurement	UNC93A PRKCA	1.13e-04	5	100	2	EFO_0800151
Disease	serum metabolite measurement	ACADS FOLH1 SHBG UNC93A ERMP1 C2orf78 GTF2B PARP4 ERAP2 ARHGAP20 HPS5	3.62e-04	945	100	11	EFO_0005653
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 40	KMT2E CHAMP1	4.03e-04	9	100	2	C4225275
Disease	long QT syndrome (implicated_via_orthology)	KCNQ5 KCNQ4	5.03e-04	10	100	2	DOID:2843 (implicated_via_orthology)
Disease	Streptozotocin Diabetes	LEPR MAP3K5 AIFM1 PRKCA	5.08e-04	108	100	4	C0038433
Disease	Diabetes Mellitus, Experimental	LEPR MAP3K5 AIFM1 PRKCA	5.08e-04	108	100	4	C0011853
Disease	Alloxan Diabetes	LEPR MAP3K5 AIFM1 PRKCA	5.08e-04	108	100	4	C0002152
Disease	daytime rest measurement	VRK2 APC NRXN3 PLCB1 PRKCA EPHB1	5.15e-04	295	100	6	EFO_0007828
Disease	comparative body size at age 10, self-reported	FOLH1 SHBG LEPR CADM1 NRXN3 PKHD1 CAMTA1	5.79e-04	420	100	7	EFO_0009819
Disease	Intestinal Neoplasms	APC PRKCA	7.34e-04	12	100	2	C0021841
Disease	Intestinal Cancer	APC PRKCA	7.34e-04	12	100	2	C0346627
Disease	squamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma	BRIP1 PKHD1	8.66e-04	13	100	2	EFO_0000707, EFO_0004193, EFO_0007932
Disease	developmental and epileptic encephalopathy (implicated_via_orthology)	KCNQ5 KCNQ4	8.66e-04	13	100	2	DOID:0112202 (implicated_via_orthology)
Disease	amyotrophic lateral sclerosis, age at onset	ST3GAL3 NRXN3	1.16e-03	15	100	2	EFO_0004847, MONDO_0004976
Disease	Lipidemias	APC LEPR	1.50e-03	17	100	2	C1706412
Disease	Hyperlipidemia	APC LEPR	1.50e-03	17	100	2	C0020473
Disease	serum amyloid A-1 protein measurement	LEPR HPS5	1.68e-03	18	100	2	EFO_0008282
Disease	Autistic Disorder	APC KMT2E CADM1 NRXN3 HDLBP	1.98e-03	261	100	5	C0004352
Disease	West Syndrome	ST3GAL3 PLCB1	2.99e-03	24	100	2	C0037769
Disease	metabolite measurement	ACADS SHBG UNC93A STK10 CADM1 HPS5 EPHB1	2.99e-03	560	100	7	EFO_0004725
Disease	alcohol consumption measurement	VRK2 DDX31 ENTHD1 FMNL2 KLHL32 NRXN3 TTLL6 PKHD1 PLCB1 CAMTA1 ZW10	3.24e-03	1242	100	11	EFO_0007878
Disease	S-6-hydroxywarfarin to S-warfarin ratio measurement	DDX18 TBC1D12 HERC4	3.36e-03	88	100	3	EFO_0803332

Protein segments in the cluster

Peptide	Gene	Start	Entry
AKERWKSFSETSSEN	TBC1D12	516	O60347
TFEKHEEWLTTSPKT	CAMTA1	86	Q9Y6Y1
WSRSSEKVFVSLPTE	CUL5	536	Q93034
VFEWDSTASTVKKSS	C2orf78	126	A6NCI8
GSKEQKQAWVTPFTS	ACADS	131	P16219
QWRTSKGEKFPSTSE	BTN1A1	176	Q13410
SKELWFSDDPNVTKT	AIFM1	176	O95831
PKKVEKNTSTDEFTW	AFF2	631	P51816
KNTSTDEFTWPKPNI	AFF2	636	P51816
SEFEWSQVKPSLKST	ANKRD50	1251	Q9ULJ7
VNSSKWKSTFSPISD	DOT1L	1236	Q8TEK3
EQTPWDSIKLTFEAT	ERMP1	781	Q7Z2K6
DDVFSTLTSQWKDVP	POLN	651	Q7Z5Q5
TSWQKKSAFTRTVSP	ITSN2	871	Q9NZM3
NERLFWPFSKRSTTE	RABGAP1	436	Q9Y3P9
WPFSKRSTTENFFLK	RABGAP1	441	Q9Y3P9
ETDSVIATKKSAFWS	EPHB1	116	P54762
WSSKEEFISPDLRVS	ENTHD1	336	Q8IYW4
KKQVAEAWSRRTPFS	OGFOD1	36	Q8N543
FWKPSTDTLSREIET	MUC16	1606	Q8WXI7
NPSWKSSLFVEKTSS	MUC16	10006	Q8WXI7
FKAWNDTTKAPTADT	MAGED1	181	Q9Y5V3
CEKTWSNSFKASPER	IZUMO1R	186	A6ND01
WKNSTFKPTTENDDT	GPBP1	446	Q86WP2
ENSWTKLTERFFKNT	EIF3L	96	Q9Y262
STEPNDSLWFSLQKK	IFI44L	76	Q53G44
GSPTKVQKSWSFNDR	KCNQ5	456	Q9NR82
WFIKSSNEATNITPK	FOLH1	41	Q04609
KESIKLSYSNSPSVW	HPS5	791	Q9UPZ3
GEATSPTKVQKSWSF	KCNQ4	471	P56696
PTKVQKSWSFNDRTR	KCNQ4	476	P56696
PSEEPVKSFSKTQRW	DDX59	86	Q5T1V6
VKSFSKTQRWAEPGE	DDX59	91	Q5T1V6
SRSKFQKNTVSSGPW	EDEM2	511	Q9BV94
SQDGTSKNWFKITIP	NXF1	111	Q9UBU9
DVSKDKRFPWTTENT	PDE5A	426	O76074
STSNRKSPFTVKGNW	HERC4	331	Q5GLZ8
VWKTSKETAPAFAAN	MDM1	196	Q8TC05
KTTFDKLETETHWVP	MPP7	556	Q5T2T1
WESKDFRPNKVSETS	NRXN3	1456	Q9Y4C0
KIFTKPDPQWDSTVS	KMT2E	1371	Q8IZD2
KNSPLKDSFSNSSWE	LEPR	1016	P48357
SWEQSLFSTTKPLFS	KNL1	716	Q8NG31
KKPATTDVFWSSLSA	KIAA1549L	391	Q6ZVL6
LFKKVSPWETSTSSF	PARP4	1301	Q9UKK3
LKQSKVPLSEFDFSW	DDX18	541	Q9NVP1
SFDTVQKLLKPFTWI	DDX31	321	Q9H8H2
TSSSFDKTLKVWDTN	ERCC8	116	Q13216
PTFNKQTKRVSWSSF	BRIP1	991	Q9BX63
TDKKTDNSEVFWNPT	OSBPL8	646	Q9BZF1
SKPATTIRWFKGNTE	CADM1	171	Q9BY67
SPDLWKSSFFIEPQK	CHAMP1	476	Q96JM3
SKVTWDSSFCAVNPK	CORO6	31	Q6QEF8
TQKEASISWESSLFP	CORIN	481	Q9Y5Q5
STVESSVDKSKPWSR	FMNL2	156	Q96PY5
KKFWESASQSSPETS	RALGDS	736	Q12967
EFQAWTGVKPSRSTK	MAP6D1	136	Q9H9H5
SPKDDVWDSVSIISF	IFNGR2	311	P38484
FDPKTSSASDKLWVT	ERAP2	351	Q6P179
FPDSTFQKEVWTRLK	ECI2	321	O75521
ETEWLKSKDRTTSFF	AHCTF1	1266	Q8WYP5
LWKKFSPSDTDENAT	ERCC6L2	1541	Q5T890
ELSAWKFTPDSQTGK	WTAP	141	Q15007
WFKESDPSKLQFNTT	HMCES	81	Q96FZ2
KSVFTRSELKFSPQW	CD22	196	P20273
ITNDSLSLKPSWFDF	MIA2	366	Q96PC5
ASWFKKAFESEPTLQ	MAP3K5	416	Q99683
TSKQEASPNSDFKWV	GPRASP1	181	Q5JY77
ASPNSDFKWVDKSVS	GPRASP1	186	Q5JY77
TFSSPEQKDKWLSLL	ARHGAP20	166	Q9P2F6
NVNSSWKSEPEKFDS	RUSC1	261	Q9BVN2
VKTPTLFSTKLWEQS	TARS2	351	Q9BW92
KPLESTWTKTNSQFL	UTP25	251	Q68CQ4
EWKTFTEKHSNRPSI	TCEANC2	106	Q96MN5
LLWAKFTNSDTPTSF	TOR1AIP2	421	Q8NFQ8
FFATRTAPEEEKWST	TMC3	441	Q7Z5M5
VTDNSIFSKLPKFWE	CARS1	206	P49589
PQWNESFTFKLKPSD	PRKCA	221	P17252
ITKTSSSFEVRTWDP	SHBG	66	P04278
SDGFWKSVATRVPKE	ST3GAL3	251	Q11203
HFSWSEEPRTKVKVA	PKHD1	401	P08F94
EETFQLSRWTPFIKD	STXBP3	466	O00186
KFWESPETVSQLDSV	SMARCC1	41	Q92922
KEVTFSFIPRAKSTW	URB1	376	O60287
SRSWETFPSVEKKTP	SPAG17	1716	Q6Q759
FPTVFGKISSSTKIW	TET1	1206	Q8NFU7
TWRKIKENEFSPTNS	APC	2611	P25054
PSQLFSSVTSWKKRF	PLEKHS1	26	Q5SXH7
VAFSKTSQVLSKWDP	UTP14C	131	Q5TAP6
PKESKIATFTRNVSW	ZNF555	66	Q8NEP9
EWRTFSNDKATKDPS	GTF2B	51	Q00403
IKRWAASPKSFTLDF	TLN1	356	Q9Y490
AKQSDWPVESETTFK	SYCP2	711	Q9BX26
TLLTPSKWSVEFRDF	STK10	256	O94804
ESEGEKKSVPFWSTL	UNC93A	231	Q86WB7
SIAFKDPPSRSSFWK	SMIM44	131	A0A286YF18
TKWAFVLASAAPTKE	TECPR2	1121	O15040
PESRVEESSWKKSRF	REP15	131	Q6BDI9
FLPTKSKSFWESPNT	TTLL6	696	Q8N841
TKFVKWDDDSTIVTP	PLCB1	26	Q9NQ66
LSIFTEFNSDWPKVK	ZSWIM3	266	Q96MP5
PSTSAWTTNFDKIGK	ZNF830	126	Q96NB3
FVVRDAPWTASSSEK	HDLBP	1226	Q00341
FISDKEWKSIEPVSS	TMX1	126	Q9H3N1
KFWRKPISDNSFSSD	ZFC3H1	1291	O60293
KSEKFSWPQRSETLS	HIVEP1	1256	P15822
FTSPDIFKKSRSPSW	VRK2	436	Q86Y07
SSWESIFNKSPEVVT	TTLL7	791	Q6ZT98
NVVSLSKFSTPWKRF	SLC17A8	296	Q8NDX2
VWKFPPSKDTSSLES	ZW10	186	O43264
PKKNKWTFVQSFDRS	KLHL32	421	Q96NJ5