Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhelicase activity

DDX46 DDX60 CHD9 BTAF1 DDX39A DDX39B

9.52e-06158626GO:0004386
GeneOntologyMolecularFunctionRNA helicase activity

DDX46 DDX60 DDX39A DDX39B

1.01e-0478624GO:0003724
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

DDX46 DDX60 DDX39A DDX39B

1.12e-0480624GO:0008186
GeneOntologyMolecularFunctiondihydropyrimidinase activity

DPYSL2 DPYSL3

1.41e-046622GO:0004157
GeneOntologyMolecularFunctionTBP-class protein binding

CAND1 CAND2 BTAF1

1.46e-0433623GO:0017025
GeneOntologyMolecularFunctionATP hydrolysis activity

DDX46 DDX60 CHD9 BTAF1 ATAD2 DDX39A DDX39B

4.22e-04441627GO:0016887
GeneOntologyMolecularFunctiongeneral transcription initiation factor binding

CAND1 CAND2 BTAF1

1.04e-0364623GO:0140296
GeneOntologyMolecularFunctionpyrophosphatase activity

PRUNE2 DDX46 DDX60 CHD9 BTAF1 ATL2 ATAD2 DDX39A DDX39B

1.07e-03839629GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

PRUNE2 DDX46 DDX60 CHD9 BTAF1 ATL2 ATAD2 DDX39A DDX39B

1.08e-03840629GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

PRUNE2 DDX46 DDX60 CHD9 BTAF1 ATL2 ATAD2 DDX39A DDX39B

1.08e-03840629GO:0016818
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

DPYSL2 DPYSL3

1.11e-0316622GO:0016812
GeneOntologyMolecularFunctionribosomal large subunit binding

CPSF6 NMD3

1.25e-0317622GO:0043023
GeneOntologyBiologicalProcessSCF complex assembly

CAND1 CAND2

9.48e-062642GO:0010265
GeneOntologyBiologicalProcessnuclear export

CPSF6 DDX39A DDX39B XPOT NMD3 XPO7

2.34e-05185646GO:0051168
DomainSPAR_C

SIPA1L1 SIPA1L3 SIPA1L2

3.66e-083633PF11881
DomainSIPA1L_C

SIPA1L1 SIPA1L3 SIPA1L2

3.66e-083633IPR021818
DomainHelicase_C

DDX46 DDX60 CHD9 BTAF1 DDX39A DDX39B

1.60e-06107636PF00271
DomainHELICc

DDX46 DDX60 CHD9 BTAF1 DDX39A DDX39B

1.60e-06107636SM00490
DomainHelicase_C

DDX46 DDX60 CHD9 BTAF1 DDX39A DDX39B

1.69e-06108636IPR001650
DomainHELICASE_CTER

DDX46 DDX60 CHD9 BTAF1 DDX39A DDX39B

1.78e-06109636PS51194
DomainHELICASE_ATP_BIND_1

DDX46 DDX60 CHD9 BTAF1 DDX39A DDX39B

1.78e-06109636PS51192
DomainDEXDc

DDX46 DDX60 CHD9 BTAF1 DDX39A DDX39B

1.78e-06109636SM00487
DomainHelicase_ATP-bd

DDX46 DDX60 CHD9 BTAF1 DDX39A DDX39B

1.88e-06110636IPR014001
DomainRap_GAP

SIPA1L1 SIPA1L3 SIPA1L2

4.32e-0610633PF02145
DomainRap_GAP_dom

SIPA1L1 SIPA1L3 SIPA1L2

5.92e-0611633IPR000331
DomainRAPGAP

SIPA1L1 SIPA1L3 SIPA1L2

5.92e-0611633PS50085
DomainTATA-bd_TIP120

CAND1 CAND2

1.12e-052632IPR013932
DomainTIP120

CAND1 CAND2

1.12e-052632PF08623
DomainDEAD/DEAH_box_helicase_dom

DDX46 DDX60 DDX39A DDX39B

1.07e-0473634IPR011545
DomainDEAD

DDX46 DDX60 DDX39A DDX39B

1.07e-0473634PF00270
DomainHydantoinase/dihydroPyrase

DPYSL2 DPYSL3

1.67e-046632IPR011778
Domain-

PALS1 DDX46 DDX60 YLPM1 CHD9 BTAF1 ATL2 ATAD2 DDX39A DDX39B

1.83e-0474663103.40.50.300
DomainQ_MOTIF

DDX46 DDX39A DDX39B

2.62e-0437633PS51195
DomainRNA_helicase_DEAD_Q_motif

DDX46 DDX39A DDX39B

2.62e-0437633IPR014014
DomainARM-like

CAND1 CAND2 BTAF1 ATAD2 XPOT XPO7

2.94e-04270636IPR011989
Domain-

DPYSL2 DPYSL3

3.09e-0486322.30.40.10
DomainAmidohydro_1

DPYSL2 DPYSL3

4.95e-0410632PF01979
DomainMetal-dep_hydrolase_composite

DPYSL2 DPYSL3

4.95e-0410632IPR011059
DomainP-loop_NTPase

PALS1 DDX46 DDX60 YLPM1 CHD9 BTAF1 ATL2 ATAD2 DDX39A DDX39B

5.07e-048486310IPR027417
DomainHEAT

CAND1 CAND2 BTAF1

5.68e-0448633PF02985
DomainAmidohydro-rel

DPYSL2 DPYSL3

6.04e-0411632IPR006680
Domain-

CAND1 CAND2 BTAF1 ATAD2 XPOT

9.10e-042226351.25.10.10
DomainARM-type_fold

CAND1 CAND2 BTAF1 RYR3 XPOT XPO7

9.74e-04339636IPR016024
DomainHEAT

CAND1 CAND2 BTAF1

9.89e-0458633IPR000357
DomainIBN_N

XPOT XPO7

1.14e-0315632PF03810
DomainIBN_N

XPOT XPO7

1.30e-0316632SM00913
DomainPDZ

PALS1 SIPA1L1 SIPA1L3 SIPA1L2

1.31e-03141634PF00595
DomainImportin-beta_N

XPOT XPO7

1.47e-0317632IPR001494
DomainPDZ

PALS1 SIPA1L1 SIPA1L3 SIPA1L2

1.57e-03148634SM00228
Domain-

PALS1 SIPA1L1 SIPA1L3 SIPA1L2

1.65e-031506342.30.42.10
DomainPDZ

PALS1 SIPA1L1 SIPA1L3 SIPA1L2

1.69e-03151634PS50106
DomainHEAT_REPEAT

CAND1 CAND2 BTAF1

1.70e-0370633PS50077
DomainPDZ

PALS1 SIPA1L1 SIPA1L3 SIPA1L2

1.73e-03152634IPR001478
DomainMetal_Hydrolase

DPYSL2 DPYSL3

2.95e-0324632IPR032466
DomainSNF2_N

CHD9 BTAF1

5.20e-0332632IPR000330
DomainSNF2_N

CHD9 BTAF1

5.20e-0332632PF00176
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MYT1L SOX6 DPYSL2 CAND1 RSPH1 SIPA1L1 SIPA1L3 YLPM1 CCAR1 ROBO1 CHD9 CMYA5 SLC4A3 LDB2 RYR3 XPOT

1.01e-091285641635914814
Pubmed

RapGAPs in brain: multipurpose players in neuronal Rap signalling.

SIPA1L1 SIPA1L3 SIPA1L2

5.94e-09364320576033
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

FLG DPYSL2 DDX46 CAND1 CPSF6 POLR2B YLPM1 CCAR1 CHD9 SIPA1L2 DDX39A DDX39B UNC13A

7.19e-081082641338697112
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MYT1L HNRNPDL CAND2 CPSF6 ANAPC15 SIPA1L1 POLR2B GOLM1 PLD1 DDX39A NMT1 SPTY2D1 XPOT

7.34e-081084641311544199
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

DPYSL2 DPYSL3 DDX46 CAND1 SIPA1L1 POLR2B CCAR1

2.63e-0723564730258100
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

DDX46 CPSF6 POLR2B ASCC1 CCAR1 CHD9 TTC6 RYR3 XPOT

3.17e-0749764936774506
Pubmed

The protein interaction landscape of the human CMGC kinase group.

DDX46 CAND1 ZNF460 CPSF6 SIPA1L1 SIPA1L3 POLR2B SIPA1L2 DDX39A DDX39B

5.46e-07695641023602568
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

PRUNE2 DPYSL2 DPYSL3 CAND1 POLR2B ARIH1 CMYA5 SNCA DDX39A NMT1 DDX39B XPOT XPO7

2.04e-061455641322863883
Pubmed

Nuclear localization of poly(A)+ mRNA following siRNA reduction of expression of the mammalian RNA helicases UAP56 and URH49.

DDX39A DDX39B

3.33e-06264216949217
Pubmed

Terminal regions of UAP56 and URH49 are required for their distinct complex formation functioning to an essential role in mRNA processing and export.

DDX39A DDX39B

3.33e-06264238377942
Pubmed

Binding of the human cytomegalovirus (HCMV) tegument protein UL69 to UAP56/URH49 is not required for efficient replication of HCMV.

DDX39A DDX39B

3.33e-06264220610707
Pubmed

Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes.

DDX39A DDX39B

3.33e-06264238225262
Pubmed

The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression.

DDX39A DDX39B

3.33e-06264220573985
Pubmed

Sipa1l3/SPAR3 is targeted to postsynaptic specializations and interacts with the Fezzin ProSAPiP1/Lzts3.

SIPA1L1 SIPA1L3

3.33e-06264226364583
Pubmed

Phosphorylation of CRMP2 is involved in proper bifurcation of the apical dendrite of hippocampal CA1 pyramidal neurons.

DPYSL2 DPYSL3

3.33e-06264222826151
Pubmed

Phospholipase D1 downregulation by α-synuclein: Implications for neurodegeneration in Parkinson's disease.

PLD1 SNCA

3.33e-06264229571767
Pubmed

Parsing the roles of DExD-box proteins DDX39A and DDX39B in alternative RNA splicing.

DDX39A DDX39B

3.33e-06264238801080
Pubmed

alpha-Synuclein interacts with phospholipase D isozymes and inhibits pervanadate-induced phospholipase D activation in human embryonic kidney-293 cells.

PLD1 SNCA

3.33e-06264211821392
Pubmed

Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.

HNRNPDL CAND1 CAND2 POLR2B BTAF1 DDX39A

5.98e-0624464630349055
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

HNRNPDL DPYSL2 DDX46 CAND1 CPSF6 YLPM1 CCAR1 ARIH1 ATL2 DDX39A NMT1 XPO7

6.41e-061367641232687490
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

HNRNPDL DPYSL2 DDX60 YLPM1 ASCC1 CCAR1 NMT1 CPED1 DDX39B

6.93e-0672464936232890
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

HNRNPDL PALS1 DPYSL2 DPYSL3 DDX46 CAND1 CAND2 CPSF6 POLR2B NMT1 DDX39B

7.29e-061149641135446349
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

DPYSL2 DPYSL3 DDX46 CAND1 ZFYVE16 CPSF6 YLPM1 BTAF1 SIPA1L2 NMT1

7.58e-06934641033916271
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

HNRNPDL DENND4A CAND1 CPSF6 POLR2B CCAR1 CMYA5 ATL2 ATAD2 DDX39B XPOT NMD3

9.74e-061425641230948266
Pubmed

TIP120B: a novel TIP120-family protein that is expressed specifically in muscle tissues.

CAND1 CAND2

9.99e-06364210441524
Pubmed

The RNA helicase DDX39B and its paralog DDX39A regulate androgen receptor splice variant AR-V7 generation.

DDX39A DDX39B

9.99e-06364228025139
Pubmed

TBP-interacting protein 120B, which is induced in relation to myogenesis, binds to NOT3.

CAND1 CAND2

9.99e-06364212207886
Pubmed

Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56.

DDX39A DDX39B

9.99e-06364215047853
Pubmed

Hcc-1 is a novel component of the nuclear matrix with growth inhibitory function.

DDX39A DDX39B

9.99e-06364215338056
Pubmed

Proteomic analysis of neonatal mouse brain: evidence for hypoxia- and ischemia-induced dephosphorylation of collapsin response mediator proteins.

DPYSL2 DPYSL3

9.99e-06364218471005
Pubmed

Aberrant expression of dihydropyrimidinase related proteins-2,-3 and -4 in fetal Down syndrome brain.

DPYSL2 DPYSL3

9.99e-06364211771764
Pubmed

Interferon-induced antiviral protein MxA interacts with the cellular RNA helicases UAP56 and URH49.

DDX39A DDX39B

9.99e-06364221859714
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

PALS1 SIPA1L1 SIPA1L3 POLR2B CCAR1 DDX39B

1.16e-0527464634244482
Pubmed

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.

SOX6 COL11A1 BET1L CPED1

1.41e-057964422504420
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

HNRNPDL CAND1 DDX60 BTAF1 XPOT NMD3

1.45e-0528564632838362
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

HNRNPDL DPYSL2 ZFYVE16 CPSF6 SIPA1L1 SIPA1L3 CCAR1 DDX39A NMT1 SPTY2D1

1.45e-051007641034597346
Pubmed

Characterization of carbonic anhydrase IX interactome reveals proteins assisting its nuclear localization in hypoxic cells.

CAND1 CAND2 XPOT

1.50e-052664323181366
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

HNRNPDL PALS1 CPSF6 DDX60 SIPA1L1 SIPA1L3 POLR2B CD109 ASCC1 NMT1 DDX39B

1.69e-051257641136526897
Pubmed

CRMP2 tethers kainate receptor activity to cytoskeleton dynamics during neuronal maturation.

DPYSL2 DPYSL3

2.00e-05464224227739
Pubmed

The Ulip family phosphoproteins--common and specific properties.

DPYSL2 DPYSL3

2.00e-0546429652388
Pubmed

ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex.

DDX39A DDX39B

2.00e-05464220844015
Pubmed

Regulation of expression of phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them.

PLD1 ARIH1

2.00e-05464210926929
Pubmed

Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous system.

DPYSL2 DPYSL3

2.00e-05464210664068
Pubmed

The BAT1 gene in the MHC encodes an evolutionarily conserved putative nuclear RNA helicase of the DEAD family.

DDX39A DDX39B

2.00e-0546427601445
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

DPYSL2 CAND1 ZFYVE16 POLR2B CD109 CCAR1 ROBO1 GOLM1 ARIH1 DDX39A XPOT

2.25e-051297641133545068
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PLEKHG1 DPYSL2 DPYSL3 SIPA1L1 SIPA1L3 POLR2B SNCA SIPA1L2 NMT1

2.54e-0585364928718761
Pubmed

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.

DPYSL2 DPYSL3 CPSF6 SIPA1L1 POLR2B ATAD2

2.54e-0531564626777405
Pubmed

The cellular DExD/H-box RNA-helicases UAP56 and URH49 exhibit a CRM1-independent nucleocytoplasmic shuttling activity.

DDX39A DDX39B

3.32e-05564221799930
Pubmed

Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo.

DPYSL2 DPYSL3

3.32e-05564216611631
Pubmed

A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.

DPYSL2 DPYSL3

3.32e-0556428973361
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DENND4A SIPA1L1 SIPA1L3 ROBO1 SIPA1L2

4.27e-0520964536779422
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

SIPA1L1 SIPA1L3 CCAR1 ARIH1 NMD3

4.57e-0521264533853758
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

HNRNPDL LRRC66 PALS1 CPSF6 SIPA1L1 SIPA1L3 POLR2B YLPM1 DDX39B

4.64e-0592264927609421
Pubmed

Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.

DPYSL2 DPYSL3

4.98e-05664210956643
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

DPYSL2 CPSF6 POLR2B YLPM1 ROBO1 PLD1

5.17e-0535864632460013
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

SIPA1L1 SIPA1L3 ARIH1 SIPA1L2 LDB2

5.22e-0521864533378226
Pubmed

Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.

PALS1 CPSF6 POLR2B YLPM1 DDX39B

5.45e-0522064524550385
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

DDX46 CAND1 CAND2 DDX60 SIPA1L1 POLR2B CD109 ASCC1 BET1L BTAF1 XPOT

5.83e-051440641130833792
Pubmed

Rho-associated protein kinase-dependent moesin phosphorylation is required for PD-L1 stabilization in breast cancer.

HNRNPDL CAND1 NMT1 XPOT XPO7

5.93e-0522464532941674
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

PALS1 DPYSL2 CAND1 SIPA1L1 SIPA1L3 YLPM1 CCAR1 UNC13A LDB2

6.48e-0596364928671696
Pubmed

Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.

ZFYVE16 BTAF1 ATAD2

6.96e-054364334672947
Pubmed

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.

SOX6 PLEKHG1

6.96e-05764223972371
Pubmed

The steady-state repertoire of human SCF ubiquitin ligase complexes does not require ongoing Nedd8 conjugation.

CAND1 CAND2

6.96e-05764221169563
Pubmed

TREX is a conserved complex coupling transcription with messenger RNA export.

DDX39A DDX39B

6.96e-05764211979277
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

POLR2B BTAF1 DDX39A XPOT

7.30e-0512064427320910
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PRUNE2 DPYSL2 CAND1 NACC2 SIPA1L3 BLNK CCAR1 CHD9 BTAF1 ARIH1 XPO7

7.86e-051489641128611215
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

HNRNPDL CPSF6 YLPM1 CCAR1 ATL2 ATAD2 SPTY2D1 DDX39B NMD3

7.94e-0598964936424410
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

DDX46 CAND1 CPSF6 SIPA1L1 SIPA1L3 POLR2B ASCC1 CCAR1 ATAD2 NMT1 SPTY2D1

8.24e-051497641131527615
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

HNRNPDL DDX46 SIPA1L1 YLPM1 CCAR1 BTAF1 ATAD2 NMT1

8.56e-0577464815302935
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

HNRNPDL CAND1 CPSF6 BET1L ROBO1 PLD1 SPTY2D1 XPO7

8.79e-0577764835844135
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

PALS1 CAND1 CPSF6 SIPA1L1 SIPA1L3 POLR2B ASCC1 CHD9 DDX39A DDX39B

8.82e-051247641027684187
Pubmed

CRMP-2 binds to tubulin heterodimers to promote microtubule assembly.

DPYSL2 DPYSL3

9.27e-05864212134159
Pubmed

A HECT domain E3 enzyme assembles novel polyubiquitin chains.

CAND1 CAND2

9.27e-05864211278995
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

DPYSL2 DDX46 CAND1 POLR2B YLPM1 CCAR1 CHD9 ARIH1 XPO7

9.60e-05101464932416067
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DDX46 CAND1 CPSF6 YLPM1 BTAF1 DDX39A DDX39B

9.65e-0558264720467437
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

HNRNPDL DDX46 CAND1 CPSF6 POLR2B YLPM1 BTAF1 DDX39B XPO7

1.03e-04102464924711643
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

HNRNPDL DDX46 CPSF6 POLR2B YLPM1 CCAR1 DDX39A DDX39B

1.14e-0480764822681889
Pubmed

CRMP2 mediates Sema3F-dependent axon pruning and dendritic spine remodeling.

DPYSL2 DPYSL3

1.19e-04964231919978
Pubmed

Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily.

XPOT XPO7

1.19e-04964211024021
Pubmed

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.

DDX39A DDX39B

1.19e-04964222197932
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

HNRNPDL FLG DDX46 YLPM1 CCAR1 DDX39A DDX39B

1.23e-0460564728977666
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

CAND1 CAND2 NLRX1 POLR2B ASCC1 SIPA1L2 XPOT

1.24e-0460664736538041
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

HNRNPDL DDX46 CAND1 CPSF6 POLR2B CCAR1 DDX39A DDX39B XPOT NMD3

1.39e-041318641030463901
Pubmed

Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions.

SOX6 XPO7

1.49e-041064220711497
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

HNRNPDL PALS1 CAND1 ZFYVE16 POLR2B ASCC1 ARIH1 DDX39B TTC6 NMD3

1.54e-041335641029229926
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

HNRNPDL DDX46 CAND1 POLR2B CCAR1 DDX39B XPOT

1.70e-0463864733239621
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

HNRNPDL DPYSL2 CAND1 POLR2B CCAR1 ATAD2 DDX39A DDX39B XPOT NMD3

1.72e-041353641029467282
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

PLEKHG1 PALS1 DENND4A SIPA1L1 SIPA1L3 SIPA1L2

1.72e-0444664624255178
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

CAND1 CPSF6 POLR2B CMYA5 NMT1 XPOT

1.83e-0445164636168627
Pubmed

WW domains provide a platform for the assembly of multiprotein networks.

DDX46 CPSF6 POLR2B YLPM1

1.91e-0415464416055720
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

COL11A1 DDX46 CPSF6 SIPA1L3 YLPM1 CCAR1 PLD1 NMT1 SPTY2D1 DDX39B

1.91e-041371641036244648
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

DDX46 CAND1 CPSF6 YLPM1 BTAF1 XPOT NMD3

1.96e-0465364733742100
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DPYSL2 DDX46 YLPM1 CCAR1 ATAD2 XPOT XPO7

1.96e-0465364722586326
Pubmed

A genome-wide association study identifies protein quantitative trait loci (pQTLs).

EPC2 COL11A1 ROBO1

1.98e-046164318464913
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

HNRNPDL DDX46 SIPA1L3 YLPM1 CD109 DDX39A DDX39B

2.09e-0466064732780723
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

HNRNPDL CAND1 CPSF6 POLR2B CCAR1 DDX39B XPOT

2.29e-0467064722990118
Pubmed

A bead-based approach for large-scale identification of in vitro kinase substrates.

HNRNPDL CPSF6 NMT1 NMD3

2.37e-0416364422113938
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

HNRNPDL DDX46 ZNF460 SIPA1L3 YLPM1 CCAR1 ATL2 DDX39A DDX39B

2.54e-04115564920360068
Pubmed

Transcription factors Sp8 and Sp9 regulate the development of caudal ganglionic eminence-derived cortical interneurons.

SOX6 ROBO1

2.57e-041364231070778
Pubmed

Cand1-Mediated Adaptive Exchange Mechanism Enables Variation in F-Box Protein Expression.

CAND1 CAND2

2.57e-041364229499133
InteractionGARNL3 interactions

SIPA1L1 SIPA1L3 SIPA1L2 DDX39A

9.04e-0814644int:GARNL3
InteractionSNRPB interactions

HNRNPDL DDX46 CAND1 CPSF6 POLR2B YLPM1 CCAR1 SNCA DDX39A DDX39B

4.95e-065176410int:SNRPB
InteractionSPDL1 interactions

DPYSL2 DPYSL3 DDX46 CAND1 SIPA1L1 POLR2B YLPM1 CCAR1

6.75e-06315648int:SPDL1
InteractionFBXO22 interactions

DDX46 CPSF6 POLR2B ASCC1 CCAR1 CHD9 ARIH1 TTC6 RYR3 XPOT

7.25e-065406410int:FBXO22
InteractionSNRPA interactions

MYT1L HNRNPDL DPYSL2 CAND1 POLR2B YLPM1 CCAR1 DDX39A DDX39B

2.04e-05482649int:SNRPA
InteractionATG16L1 interactions

HNRNPDL PLEKHG1 PALS1 DENND4A ZNF460 SIPA1L1 SIPA1L3 POLR2B YLPM1 CCAR1 ROBO1 DDX39A DDX39B

6.04e-0511616413int:ATG16L1
InteractionTOP1 interactions

HNRNPDL CAND1 CPSF6 POLR2B YLPM1 CCAR1 SNCA DDX39A SPTY2D1 DDX39B

6.35e-056966410int:TOP1
GeneFamilyDEAD-box helicases

DDX46 DDX60 DDX39A DDX39B

2.91e-0642434499
GeneFamilyExportins

XPOT XPO7

1.15e-047432547
GeneFamilyPDZ domain containing

PALS1 SIPA1L1 SIPA1L3 SIPA1L2

4.59e-041524341220
CoexpressionGSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP

NACC2 CPSF6 POLR2B CHD9 XPOT XPO7

9.50e-06200646M3277
CoexpressionDODD_NASOPHARYNGEAL_CARCINOMA_UP

SOX6 DPYSL2 CAND1 CPSF6 DDX60 POLR2B CCAR1 ROBO1 ATL2 ATAD2 DDX39A XPOT NMD3

2.94e-0514076413M14427
CoexpressionYAGI_AML_WITH_T_8_21_TRANSLOCATION

DPYSL2 SIPA1L1 SIPA1L3 ROBO1 CDH19 DDX39A UNC13A

3.40e-05372647M19261
CoexpressionONKEN_UVEAL_MELANOMA_DN

HNRNPDL DPYSL2 CAND2 YLPM1 ROBO1 SNCA CDH19 NMD3

4.52e-05533648M2605
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

SOX6 PROKR1 PALS1 DPYSL3 DENND4A DDX46 NACC2 BTAF1 SIPA1L2 NMT1

2.10e-056546310Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SOX6 PRUNE2 COL11A1 ROBO1 CPED1 LDB2

4.33e-07200646a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX6 DDX46 SNCA CPED1 XPO7

5.78e-061786451a578d16008a450c42e73a996247ffecdc2c43f0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 DPYSL3 ROBO1 SNCA RYR3

6.62e-061836457c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellControl-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

PLEKHG1 SIPA1L1 SIPA1L3 BLNK CPED1

7.35e-061876454e64be635f445276e71f2937f33f041c3a4204ab
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

PLEKHG1 SIPA1L1 SIPA1L3 BLNK CPED1

7.35e-06187645af1327559f7e01bec070881cae52834917c3da65
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG1 DENND4A SIPA1L1 SIPA1L3 BLNK

8.35e-06192645446c61c0d6ba89c619efe87ee495951299953981
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SOX6 PLEKHG1 COL11A1 ROBO1 LDB2

8.35e-06192645d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG1 DPYSL3 CD109 LDB2 RYR3

8.56e-061936450b328f725f6feba263783eaca60c142e80df90f3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLG DPYSL3 COL11A1 SNCA SIPA1L2

8.78e-061946451374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG1 DENND4A SIPA1L1 SIPA1L3 BLNK

9.00e-061956450c49d22c348aec6d8a1a976e7c88d0a3b48a4244
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLG DPYSL3 COL11A1 SNCA SIPA1L2

9.23e-06196645023477a499a2c190f363cfdbc9d9c646733a6541
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLG DPYSL3 COL11A1 SNCA SIPA1L2

9.23e-061966453cb74f1a333a82cac2b459f2f1517e2acf22b5fd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG1 CD109 ROBO1 LDB2 RYR3

9.46e-06197645cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG1 CD109 ROBO1 LDB2 RYR3

9.46e-06197645412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2|World / Primary Cells by Cluster

MYT1L DPYSL2 DPYSL3 SNCA LDB2

9.93e-06199645f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLG DPYSL3 COL11A1 SNCA SIPA1L2

9.93e-06199645b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV|World / Primary Cells by Cluster

MYT1L DPYSL2 DPYSL3 SNCA LDB2

9.93e-06199645e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLG DPYSL3 COL11A1 SNCA SIPA1L2

9.93e-06199645c972d3036151403f26fa9d6271520639c281ab84
ToppCellNeuron-Postmitotic-Excitatory_Neuron_|World / Primary Cells by Cluster

MYT1L DPYSL2 DPYSL3 SNCA LDB2

9.93e-06199645058373b4ac3cec2108cb24265628ff0a50646e33
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD109 BLNK SNCA CDH19

5.36e-05143644d0ed8c25da1327085e042c2e03cb7503e2c52ce0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD109 BLNK SNCA CDH19

5.36e-051436448900b92a24289204b9ec7baccc11594fec7694f1
ToppCellEnthrocyte|World / shred on cell class and cell subclass (v4)

SOX6 PROKR1 SNCA XPO7

6.97e-05153644654265f3c14344071b2af7ca05cbdbb17ce2c5d3
ToppCellEnthrocyte|World / shred on cell class and cell subclass (v4)

SOX6 PROKR1 SNCA XPO7

6.97e-05153644105b91f5277d145f7717307d7eb9b7d8e8e23576
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX6 FSIP2 CMYA5 CDH19

7.33e-0515564477fdae85d36efb776db977eb424b32487ef222e4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 COL11A1 ROBO1 SIPA1L2

7.51e-05156644dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 COL11A1 ROBO1 SIPA1L2

7.51e-05156644abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FSIP2 PLEKHG1 SIPA1L3 BLNK

7.89e-0515864441cf950983f47a9e55d56041b301006b42853b37
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG1 DENND4A SIPA1L1 CHD9

8.91e-051636446bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellInfluenza_Severe-cDC|World / Disease group and Cell class

CD109 SNCA SLC4A3 RYR3

9.12e-05164644c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCelldroplet-Marrow-nan-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROKR1 DENND4A SNCA XPO7

9.78e-0516764454576e9863403d0d5e3046e61db1ad695d88fee4
ToppCellNS-moderate-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DPYSL2 BLNK CPED1 SLC4A3

1.00e-04168644d03e91f0e0518b33555c0ec98124fc5ed0f11be5
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

SOX6 SNCA SIPA1L2 CDH19

1.00e-0416864488c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 PLD1 CPED1 UNC13A

1.05e-0417064499dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 PLD1 CPED1 UNC13A

1.05e-041706443a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 PLD1 CPED1 UNC13A

1.05e-04170644cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

RSPH1 CD109 CMYA5 RYR3

1.07e-0417164474be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DPYSL3 ZNF460 CD109 LDB2

1.07e-041716441ae4b6a25bc9c1065cf5d95998ebcc70aee21ab5
ToppCellCOVID-19-lung-RBC|lung / Disease (COVID-19 only), tissue and cell type

SOX6 SNCA RYR3 XPO7

1.07e-041716440e8d63c8fbccdda4f1ef00de00667a50464b104b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG1 SIPA1L1 SIPA1L3 BLNK

1.07e-04171644c3e3ea09c73050372314a89b282e36ba5f339d73
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 ROBO1 SNCA RYR3

1.10e-041726446c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-erythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX6 PROKR1 SNCA XPO7

1.12e-04173644a8fb8db6061fa4d8d56a7b45004ecbd344501573
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG1 DENND4A SIPA1L1 CHD9

1.12e-04173644d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A CAND2 YLPM1 XPOT

1.15e-04174644f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell18-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

PLD1 SNCA RYR3 XPO7

1.17e-041756447130b816e0c02309c161d8e9ad7cb4bc2469e251
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 COL11A1 NACC2 CPED1

1.17e-0417564411f49f00e000cbc137e3540a6d6805cde21d96e6
ToppCell18-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

PLD1 SNCA RYR3 XPO7

1.17e-04175644cc476b4244442418b8f21721a82a36209b556b36
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

PLEKHG1 DPYSL3 SNCA LDB2

1.20e-0417664498c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

PLEKHG1 DPYSL3 SNCA LDB2

1.20e-04176644c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellwk_08-11-Mesenchymal-Chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SOX6 PLEKHG1 COL11A1 LDB2

1.20e-041766441af28b701c4598ce761f85adbd5d79e4918d265a
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX6 NACC2 SNCA CDH19

1.22e-0417764459cf56c385c324f0844f20003d2b5049a2791e45
ToppCelldroplet-Spleen-nan-24m-Hematologic-erythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX6 PROKR1 SNCA XPO7

1.25e-041786449c4950357087212b2388116ba8866c359628694d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 CMYA5 SNCA RYR3

1.28e-041796447394e77e665bf16d3733df91bb12907be460ab44
ToppCelldroplet-Marrow-nan-24m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX6 DENND4A SNCA XPO7

1.28e-041796447e6da098976c7801d31dcc0201f813d2bc8b07fc
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX6 SNCA CDH19 LDB2

1.28e-04179644c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLEKHG1 CD109 SIPA1L2 LDB2

1.31e-04180644493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 COL11A1 NACC2 CPED1

1.33e-04181644153709b4dd3d81e09f251fa8765b58bed1932fda
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 CMYA5 SNCA RYR3

1.33e-041816445bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 COL11A1 ROBO1 SIPA1L2

1.33e-041816445f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 COL11A1 ROBO1 SIPA1L2

1.33e-04181644c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 CMYA5 SNCA RYR3

1.33e-041816448e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellwk_20-22-Hematologic-Meg-ery-Definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SOX6 DENND4A SNCA XPO7

1.36e-041826440c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL11A1 SNCA TTC6 LDB2

1.36e-0418264414a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX6 COL11A1 SNCA CDH19

1.36e-04182644a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 CMYA5 SNCA RYR3

1.39e-04183644eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLEKHG1 COL11A1 SNCA LDB2

1.39e-04183644274076a0978bce2bd53a1732045f18ef0f2d9985
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 DPYSL3 SIPA1L2 LDB2

1.39e-04183644e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROKR1 DPYSL2 CPED1 LDB2

1.42e-04184644fea4fe648e9749177d0783443dc26a7df5807883
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROKR1 DPYSL2 CPED1 LDB2

1.42e-0418464496a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROKR1 DPYSL2 CPED1 LDB2

1.42e-04184644780eb72da43527f0c72effac3423ec7384f05f20
ToppCellEndothelial-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

PROKR1 DPYSL3 LDB2 RYR3

1.45e-04185644ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX6 DENND4A SNCA XPO7

1.45e-04185644e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCelldroplet-Thymus-nan-24m-Myeloid-Plasma_cells_and_B_cells|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSPH1 NACC2 BLNK CPED1

1.45e-04185644e583f6601f9ed79b0b23d2f9426a4ba8b969230b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 CMYA5 SNCA RYR3

1.45e-041856449197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 COL11A1 ROBO1 SIPA1L2

1.45e-0418564434fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLEKHG1 CD109 SIPA1L2 LDB2

1.45e-04185644673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PALS1 CMYA5 SNCA RYR3

1.45e-04185644ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 COL11A1 ROBO1 SIPA1L2

1.45e-041856448816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellCOVID_vent-Myeloid-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

DPYSL2 ROBO1 CPED1 SLC4A3

1.48e-0418664463a5cdd3f60681762a218be32db84be8f29b88fd
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

SOX6 SIPA1L3 ROBO1 ZNF710

1.48e-04186644de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYT1L PRUNE2 CDH19 UNC13A

1.48e-041866442fdd0a80ad31cf017aafcf5dcf760ebd786b98c1
ToppCellCOVID_vent-Myeloid-Dendritic-cDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

DPYSL2 ROBO1 CPED1 SLC4A3

1.48e-0418664439457a7b43537f2c3e221f9375c95d4515424d7d
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

SOX6 SIPA1L3 ROBO1 ZNF710

1.48e-041866440b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 DPYSL3 SIPA1L2 LDB2

1.51e-04187644ea9d34bcd3bd1f36745846309ede349773de501a
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PROKR1 COL11A1 SNCA CDH19

1.51e-041876446f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX6 COL11A1 SNCA CDH19

1.51e-041876448e8b147258982b359447add5027318f5b6d51963
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLEKHG1 DPYSL3 ROBO1 CPED1

1.51e-04187644c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 CD109 SIPA1L2 LDB2

1.54e-0418864473f6ec915934154f435a376cb274b058ff7c5f35
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 COL11A1 ROBO1 SIPA1L2

1.54e-04188644b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-DC2|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DPYSL2 CPED1 SLC4A3 ZNF710

1.54e-0418864415d8dc514d5da46f6af284e7c1c92c606712dae6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG1 SIPA1L1 SIPA1L3 BLNK

1.54e-04188644d8decd9b5967873ca8320c2f9f07365f163c777f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 COL11A1 ROBO1 SIPA1L2

1.54e-04188644874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX6 PRUNE2 DPYSL3 COL11A1

1.54e-04188644006db2c2c44971ca9241c582bc89f258c785f5ed
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX6 PRUNE2 DPYSL3 COL11A1

1.54e-04188644d0e6fb4a3b3d79d3512b5500062ea285495ae526
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX6 PLEKHG1 DPYSL3 COL11A1

1.54e-041886449b95730ddd13eb4624321bab3ab4989414977ca3
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

DPYSL3 GOLM1 CMYA5 SLC4A3

1.57e-0418964487189275234b5d59484c58acbb14a09903f2b578
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX6 PLEKHG1 CD109 LDB2

1.57e-04189644c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG1 DPYSL3 CD109 LDB2

1.57e-0418964412b6f1c3bf526b90e112374bf937701f645c5780
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 DPYSL3 SIPA1L2 LDB2

1.57e-041896445d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG1 CD109 ATAD2 LDB2

1.61e-0419064431de1727822e9818652946dfb962daee77ffad68
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLEKHG1 CD109 SIPA1L2 LDB2

1.61e-04190644a3c6eec6df052105ab78b7e3c78f94218d5912eb
DiseaseQRS duration

COL11A1 NACC2 CPSF6 SIPA1L1 XPO7

4.42e-04298635EFO_0005055
Diseasehemoglobin A1 measurement

SOX6 PLEKHG1 LRRC66 NLRX1 BET1L PLD1

8.45e-04520636EFO_0007629
Diseaseblood zinc measurement

SIPA1L3 LDB2

1.10e-0323632EFO_0007584
Diseaseneurotic disorder

SOX6 SIPA1L1 YLPM1

1.33e-03101633EFO_0004257
Diseasediastolic blood pressure, unipolar depression

SOX6 PLEKHG1

1.88e-0330632EFO_0003761, EFO_0006336
Diseaseinterleukin-8 measurement

MYT1L EPC2

2.00e-0331632EFO_0004811
Diseasepack-years measurement, systolic blood pressure

SIPA1L2 CDH19

2.41e-0334632EFO_0006335, EFO_0006526
Diseasecortical thickness

PLEKHG1 DPYSL2 COL11A1 CPSF6 YLPM1 CCAR1 ROBO1 CPED1

2.46e-031113638EFO_0004840
Diseaseresponse to platinum based chemotherapy, drug allergy

MYT1L ATAD2

2.70e-0336632EFO_0004647, EFO_0009482
Diseasecardiovascular disease

SOX6 PLEKHG1 DPYSL2 SIPA1L2 NMT1

2.93e-03457635EFO_0000319
Diseaseneuroticism measurement

MYT1L SOX6 NACC2 SIPA1L1 YLPM1 SNCA CDH19

3.18e-03909637EFO_0007660

Protein segments in the cluster

PeptideGeneStartEntry
MRDQDEYSFQDEQDK

UNC13A

151

Q9UPW8
FNLDNEQPDYDMDSE

EPC2

106

Q52LR7
NFDEDGQDEYNELHM

SLC4A3

1216

P48751
EMNDYNESPDDGEVN

ANAPC15

91

P60006
EHLNFQDYDNMDFED

CPED1

381

A4D0V7
QDYDNMDFEDQNTEE

CPED1

386

A4D0V7
TEEDNNQDEYDPMEA

CCAR1

861

Q8IX12
NQDEYDPMEAEEAED

CCAR1

866

Q8IX12
MAENDVDNELLDYED

DDX39B

1

Q13838
MAEQDVENDLLDYDE

DDX39A

1

O00148
NDDQSFYADIYMEDG

DPYSL3

26

Q14195
AEDQNRYLDGMDSDF

BET1L

46

Q9NYM9
YQHEEDEEDFYQGSM

ASCC1

26

Q8N9N2
EDEEDGEEENQKRYY

ATAD2

281

Q6PL18
EKEDNEEGVYDYENT

FLG

206

P20930
DDGLMDLAINDYDFN

DENND4A

536

Q7Z401
EDMNEYSNIEEFAEG

HNRNPDL

121

O14979
MDSDEGYNYEFDEDE

ARIH1

1

Q9Y4X5
LNENYVEDDDNMFRF

NMT1

176

P30419
NDDQSFYADIYMEDG

DPYSL2

26

Q16555
TQYDAANGMDDEEDF

LDB2

326

O43679
DLPEDFSDALDEYNM

DDX60

1516

Q8IY21
GMVLYSDDENEEIDN

FSIP2

996

Q5CZC0
YNYDDEDEDENAMDA

CAND1

311

Q86VP6
MQADADDNILDYSDG

COL11A1

1561

P12107
EETNNDYETADGGYM

FCGR2C

281

P31995
EDYYNDDVLDQMGAS

NLRX1

586

Q86UT6
LDNAYSNEGFYDDME

LRRC66

416

Q68CR7
DDYDNEEILTYEEMS

PALS1

456

Q8N3R9
EQRANDYMDGDVEDP

CHD9

1721

Q3L8U1
DNAEYAERFMEENEG

CD109

656

Q6YHK3
YSDGEVNDLDNYMPE

GABRR1

401

P24046
DYENPDEHSDSEMYV

BLNK

71

Q8WV28
ANNGDAPEDRDYMDT

CPSF6

41

Q16630
DQEQYDSEYSLENFM

BTAF1

1831

O14981
DSFQVYCMEEPQDDQ

CMYA5

3736

Q8N3K9
ENYEDDDLVNSDEVM

ATL2

41

Q8NHH9
RGEDDYNMDENEAES

GOLM1

346

Q8NBJ4
ENDQDAMEYSSEEEE

DDX46

286

Q7L014
DPNYNYDSDEDEEQM

CAND2

311

O75155
YDNDIGENAEMDYSI

CDH19

281

Q9H159
DNEAYEMPSEEGYQD

SNCA

121

P37840
DFEYDVMGQNIDEDL

PRUNE2

2351

Q8WUY3
YFEDVANAMEEANEE

PLD1

361

Q13393
MYDADEDMQYDEDDD

POLR2B

1

P30876
EEMYNNESAGPAFEE

SIPA1L1

626

O43166
EEEMYNNETAGPAFE

SIPA1L2

621

Q9P2F8
SEEEMYNNEEAGPAF

SIPA1L3

636

O60292
MAYSFQEPLEEEEDE

SETD6

221

Q8TBK2
FRYDMDEGNINSEEE

RSPH1

286

Q8WYR4
SQGTDREYEMEEENE

SPTY2D1

116

Q68D10
NGEDEMEMYDDYEDD

SOX6

796

P35712
NFSYSDYDMPLDEDE

PROKR1

36

Q8TCW9
EGENSYKFEEMFNEN

ZNF460

166

Q14592
EEAMADYNQALDLED

TTC6

501

Q86TZ1
AEADENDMFNYVDFV

RYR3

3966

Q15413
QEMEDFEENAYSYAS

ZNF710

626

Q8N1W2
EYNISVDESYDQEMP

ROBO1

1201

Q9Y6N7
DQDMDEDYNREMERD

YLPM1

1271

P49750
DEEYNFENEGEDEAM

XPOT

386

O43592
FENEGEDEAMFVEYR

XPOT

391

O43592
LMVDLGEDEDQYEQF

XPO7

676

Q9UIA9
ENEDDEDDYQMFVPS

PLEKHG1

551

Q9ULL1
NDMDGQDLDYFNIDE

ZFYVE16

506

Q7Z3T8
DDEAYDTMVEEQYGQ

NACC2

271

Q96BF6
MQDTEKDDNNNDEYD

MYT1L

181

Q9UL68
MDTDDERQYQDFLED

NMD3

431

Q96D46