Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentextrinsic component of plasma membrane

MYD88 CDH20 GNAS PCSK9 AKAP9 DCHS1 CDH7 CDH12 CDH18

4.61e-061371909GO:0019897
GeneOntologyCellularComponentextrinsic component of membrane

MYD88 CDH20 GNAS PCSK9 PLEKHG4 AKAP9 DCHS1 ATM CDH7 CDH12 CDH18

8.72e-0623019011GO:0019898
GeneOntologyCellularComponentcatenin complex

CDH20 DCHS1 CDH7 CDH12 CDH18

9.71e-06321905GO:0016342
GeneOntologyCellularComponentapical junction complex

EPPK1 ASH1L SYNPO SHROOM4 NHS FBF1 YBX3 SHROOM2 SHROOM1

1.47e-051581909GO:0043296
GeneOntologyCellularComponentperoxisome

ACOT4 PEX11B PEX11A ACOX3 HSD17B4 PNPLA8 ATM HAO2

1.20e-041621908GO:0005777
GeneOntologyCellularComponentmicrobody

ACOT4 PEX11B PEX11A ACOX3 HSD17B4 PNPLA8 ATM HAO2

1.20e-041621908GO:0042579
GeneOntologyCellularComponentmicrobody lumen

ACOT4 ACOX3 HSD17B4 ATM HAO2

1.42e-04551905GO:0031907
GeneOntologyCellularComponentperoxisomal matrix

ACOT4 ACOX3 HSD17B4 ATM HAO2

1.42e-04551905GO:0005782
GeneOntologyCellularComponentprotein complex involved in cell adhesion

ITGA6 ITGAE LAMB2 LAMC1 MMRN2

1.98e-04591905GO:0098636
GeneOntologyCellularComponentlaminin-11 complex

LAMB2 LAMC1

2.45e-0431902GO:0043260
GeneOntologyCellularComponentcell-cell junction

EPPK1 ASH1L ITGA6 SYNPO EPB41L3 SHROOM4 CDH20 NHS FBF1 YBX3 SHROOM2 SHROOM1 CDH7 CDH12 CDH18

3.44e-0459119015GO:0005911
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMB2 LAMC1 MMRN2

4.58e-04171903GO:0098637
GeneOntologyCellularComponentadherens junction

ITGA6 SHROOM4 CDH20 SHROOM2 SHROOM1 CDH7 CDH12 CDH18

7.36e-042121908GO:0005912
GeneOntologyCellularComponentactin cytoskeleton

MYO1C MYO7B SPTA1 PPP1R12B SYNPO ADCY8 SHROOM4 CCN5 WASF1 CCDC102A CAPN2 SHROOM2 GAS2L1 SHROOM1

8.26e-0457619014GO:0015629
GeneOntologyCellularComponentbicellular tight junction

EPPK1 ASH1L SYNPO NHS YBX3 SHROOM2

1.27e-031311906GO:0005923
GeneOntologyCellularComponentcortical actin cytoskeleton

SPTA1 SHROOM4 CAPN2 SHROOM2 SHROOM1

1.60e-03931905GO:0030864
GeneOntologyCellularComponenttight junction

EPPK1 ASH1L SYNPO NHS YBX3 SHROOM2

1.72e-031391906GO:0070160
GeneOntologyCellularComponentmembrane raft

PLVAP MYO1C HLA-E CBLC ADCY8 STOML1 TRPM8 CAPN2 LRP6 HYAL2

1.82e-0336219010GO:0045121
GeneOntologyCellularComponentmembrane microdomain

PLVAP MYO1C HLA-E CBLC ADCY8 STOML1 TRPM8 CAPN2 LRP6 HYAL2

1.89e-0336419010GO:0098857
GeneOntologyCellularComponentcondensin complex

NCAPD2 NCAPH

2.22e-0381902GO:0000796
DomainShroom_fam

SHROOM4 SHROOM2 SHROOM1

3.99e-0641883IPR027685
DomainASD2_dom

SHROOM4 SHROOM2 SHROOM1

3.99e-0641883IPR014799
DomainASD2

SHROOM4 SHROOM2 SHROOM1

3.99e-0641883PF08687
DomainASD2

SHROOM4 SHROOM2 SHROOM1

3.99e-0641883PS51307
DomainTwist-related

TWIST1 TWIST2

1.01e-0421882IPR015789
DomainCadherin_C

CDH20 CDH7 CDH12 CDH18

1.07e-04251884PF01049
DomainCadherin_cytoplasmic-dom

CDH20 CDH7 CDH12 CDH18

1.07e-04251884IPR000233
DomainCadherin_CS

CDH20 PCDHA5 CELSR3 DCHS1 CDH7 CDH12 CDH18

1.17e-041091887IPR020894
DomainChromo

CDY2A CHD9 CHD8 CDY1

1.25e-04261884PF00385
DomainCADHERIN_1

CDH20 PCDHA5 CELSR3 DCHS1 CDH7 CDH12 CDH18

1.47e-041131887PS00232
DomainCadherin

CDH20 PCDHA5 CELSR3 DCHS1 CDH7 CDH12 CDH18

1.47e-041131887PF00028
DomainCADHERIN_2

CDH20 PCDHA5 CELSR3 DCHS1 CDH7 CDH12 CDH18

1.56e-041141887PS50268
Domain-

CDH20 PCDHA5 CELSR3 DCHS1 CDH7 CDH12 CDH18

1.56e-0411418872.60.40.60
DomainCA

CDH20 PCDHA5 CELSR3 DCHS1 CDH7 CDH12 CDH18

1.64e-041151887SM00112
DomainCHROMO_1

CDY2A CHD9 CHD8 CDY1

1.69e-04281884PS00598
DomainCHROMO_2

CDY2A CHD9 CHD8 CDY1

1.69e-04281884PS50013
DomainARM-type_fold

CUL9 ARMC2 ITPR1 IFRD2 NCAPD2 HECTD1 GCN1 UNC79 RANBP17 ATM LRBA XPO7

1.73e-0433918812IPR016024
DomainCadherin-like

CDH20 PCDHA5 CELSR3 DCHS1 CDH7 CDH12 CDH18

1.73e-041161887IPR015919
DomainCadherin

CDH20 PCDHA5 CELSR3 DCHS1 CDH7 CDH12 CDH18

1.93e-041181887IPR002126
DomainCatenin_binding_dom

CDH20 CDH7 CDH12 CDH18

1.94e-04291884IPR027397
Domain-

CDH20 CDH7 CDH12 CDH18

1.94e-042918844.10.900.10
DomainEGF_LAM_2

HSPG2 LAMB2 LAMC1 CELSR3

2.22e-04301884PS50027
DomainEGF_LAM_1

HSPG2 LAMB2 LAMC1 CELSR3

2.22e-04301884PS01248
DomainChromodomain-like

CDY2A CHD9 CHD8 CDY1

2.87e-04321884IPR016197
DomainPEX11

PEX11B PEX11A

3.00e-0431882PF05648
DomainPEX11

PEX11B PEX11A

3.00e-0431882IPR008733
DomainASD1

SHROOM2 SHROOM1

3.00e-0431882PF08688
DomainASD1_dom

SHROOM2 SHROOM1

3.00e-0431882IPR014800
DomainASD1

SHROOM2 SHROOM1

3.00e-0431882PS51306
DomainChromo/shadow_dom

CDY2A CHD9 CHD8 CDY1

3.24e-04331884IPR000953
DomainCHROMO

CDY2A CHD9 CHD8 CDY1

3.24e-04331884SM00298
DomainEGF_Lam

HSPG2 LAMB2 LAMC1 CELSR3

4.08e-04351884SM00180
DomainLaminin_EGF

HSPG2 LAMB2 LAMC1 CELSR3

4.08e-04351884PF00053
DomainLaminin_EGF

HSPG2 LAMB2 LAMC1 CELSR3

5.62e-04381884IPR002049
Domain-

TWIST1 TCF24 HAND2 TCF15 TWIST2 TCF23

8.25e-0410918864.10.280.10
DomainHLH

TWIST1 TCF24 HAND2 TCF15 TWIST2 TCF23

9.07e-041111886PF00010
DomainSCP2_sterol-bd_dom

STOML1 HSD17B4

9.88e-0451882IPR003033
Domain-

STOML1 HSD17B4

9.88e-04518823.30.1050.10
DomainSCP2

STOML1 HSD17B4

9.88e-0451882PF02036
DomainHLH

TWIST1 TCF24 HAND2 TCF15 TWIST2 TCF23

1.14e-031161886SM00353
DomainBHLH

TWIST1 TCF24 HAND2 TCF15 TWIST2 TCF23

1.19e-031171886PS50888
DomainbHLH_dom

TWIST1 TCF24 HAND2 TCF15 TWIST2 TCF23

1.25e-031181886IPR011598
DomainBRK

CHD9 CHD8

1.47e-0361882SM00592
DomainBRK_domain

CHD9 CHD8

1.47e-0361882IPR006576
DomainBRK

CHD9 CHD8

1.47e-0361882PF07533
DomainARM-like

CUL9 ARMC2 IFRD2 NCAPD2 HECTD1 GCN1 RANBP17 LRBA XPO7

1.70e-032701889IPR011989
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

ITGA6 ITGAE CDH20 HRAS PLCB4 CDH7 CDH12 CDH18

2.44e-051211388M39823
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 TANC2 EPPK1 CBLC CUL9 SFI1 CNTROB ACOX3 CABLES1 EIF4ENIF1 IFRD2 EXOSC6 NCAPD2 HECTD1 GCN1 HSPG2 POLRMT LAMB2 CHD8 GAS2L1 CELSR3 TANC1 LRBA ELL

1.37e-0811051932435748872
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

EPPK1 MYO1C CUL9 EPB41L3 PRRC2C NCAPD2 HECTD1 GCN1 DNMT1 DHX16 POLR1A PHRF1 POLRMT NOL11 CHD8 RBM6 ATM XPO7

3.01e-086531931822586326
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 IQSEC2 EPB41L3 CDCA2 FSIP2 PTPN13 PRRC2C NHS GNAS HECTD1 DNMT1 CCDC102A NELFCD LAMC1 AKAP9 CNKSR3 TANC1 R3HDM1 CDC25B

3.85e-078611931936931259
Pubmed

Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy.

CDH20 CDH7 CDH12 CDH18

4.39e-0712193422102170
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

SPTA1 ITGA6 ARMC2 CNTROB TWIST1 TCF24 FSIP2 PTPN13 AFG3L2

4.58e-07168193930631154
Pubmed

Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins.

SHROOM4 SHROOM2 SHROOM1

6.70e-074193316684770
Pubmed

A new standard nomenclature for proteins related to Apx and Shroom.

SHROOM4 SHROOM2 SHROOM1

6.70e-074193316615870
Pubmed

Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities.

TWIST1 HAND2 TWIST2

6.70e-074193315735646
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

EPPK1 MYO1C PSMB2 HLA-E PABPC5 PRRC2C EXOSC6 UGDH NCAPD2 HSD17B4 CAPN2 ABCC11 UBXN1 NCAPH LRBA ZW10

7.67e-076471931626618866
Pubmed

Differential Spatiotemporal Expression of Type I and Type II Cadherins Associated With the Segmentation of the Central Nervous System and Formation of Brain Nuclei in the Developing Mouse.

CDH20 CDH7 CDH12 CDH18

1.20e-0615193433833667
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

CUL9 TWIST1 TCF24 HOXD13 PRRC2C NCAPD2 WASF1 VARS1 DHX16 PLEKHG4 NELFCD POLRMT UFL1 NCAPH KIF7 SYNGR3 CUX1 XPO7

1.59e-068571931825609649
Pubmed

The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1.

HSPG2 LAMB2 LAMC1

1.67e-06519337670489
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MYO1C PPP1R12B PSMB2 ITGA6 CNTROB ITPR1 CDCA2 PTPN13 SSH3 AFG3L2 NHS HSD17B4 WASF1 GCN1 DNMT1 KIF7 AKAP9 LRP6 TANC1 CDC25B

1.80e-0610491932027880917
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MYD88 ASH1L SYNPO ARMC2 ESCO1 PTPN13 PLCB4 GNAS HECTD1 POLR1A CHD9 PAM16 GRIK1 SHROOM2 OPRL1 RANBP17 RBM6 ZFHX2 ZFHX3 ANKRD24 TANC1 LRBA CUX1 XPO7

2.99e-0614891932428611215
Pubmed

Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins.

ITGA6 LAMB2 LAMC1

3.32e-066193310671376
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

EPB41L3 CABLES1 CROCC2 AFG3L2 NCAPD2 PLCB4 POLR1A POLRMT CHD9 ATM LRBA HAO2 CDH7

4.71e-064971931336774506
Pubmed

Expression of a twist-related gene, Bbtwist, during the development of a lancelet species and its relation to cephalochordate anterior structures.

TWIST1 HAND2 TCF15

5.79e-06719339520323
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYO1C PSMB2 EPB41L3 MIDEAS CDCA2 AFG3L2 UGDH NCAPD2 GCN1 VARS1 DNMT1 DHX16 POLR1A PLEKHG4 CAPN2 POLRMT NOL11 CHD8 YBX3 UBXN1 NCAPH TANC1

6.95e-0613531932229467282
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

IQSEC2 SRI ASH1L CUL9 SYNPO PTPN13 HSD17B4 HECTD1 VARS1 MTUS2 DNMT1 CHD9 GRIK1 SHROOM2 VPS9D1 CELSR3 ANKRD24 ATM LRBA R3HDM1 CUX1

1.06e-0512851932135914814
Pubmed

Laminin γ1 C-terminal Glu to Gln mutation induces early postimplantation lethality.

ITGA6 HSPG2 LAMC1

1.38e-059193330456378
Pubmed

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions.

SHROOM4 SHROOM2 SHROOM1

1.38e-059193317666436
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYO1C SPTA1 PPP1R12B ASH1L SYNPO PABPC5 EPB41L3 PEX11A CDCA2 PRRC2C NCAPD2 HSD17B4 VARS1 CACNA1E NELFCD FBF1 CCDC150 YBX3 NCAPH CNKSR3 ATM CUX1

1.86e-0514421932235575683
Pubmed

Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins.

CDH7 CDH12 CDH18

1.96e-0510193310861224
Pubmed

Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo.

ITGA6 HSPG2 LAMC1

1.96e-0510193316554364
Pubmed

Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.

PRRC2C GCN1 CHD8 AKAP9 DCHS1 CUX1

2.21e-05101193626949739
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

JPH4 PSMB2 CUL9 EPB41L3 MIDEAS CROCC2 EXOSC6 POLR1A PHRF1 LAMB2 GRIK1 RBM6

2.38e-054961931231343991
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

EPB41L3 PTPN13 EIF4ENIF1 GCN1 NELFCD POLRMT LAMC1 CHD8 ZFHX3 LRBA CUX1

2.44e-054181931134709266
Pubmed

TWIST1 and TWIST2 regulate glycogen storage and inflammatory genes in skeletal muscle.

TWIST1 TWIST2

3.06e-052193225663706
Pubmed

Intricate gene regulatory networks of helix-loop-helix (HLH) proteins support regulation of bone-tissue related genes during osteoblast differentiation.

TWIST1 TWIST2

3.06e-052193218655182
Pubmed

MyD88 hypermethylation mediated by DNMT1 is associated with LTA-induced inflammatory response in human odontoblast-like cells.

MYD88 DNMT1

3.06e-052193230707290
Pubmed

Involvement of cadherins 7 and 20 in mouse embryogenesis and melanocyte transformation.

CDH20 CDH7

3.06e-052193215273735
Pubmed

Targeted oncogenesis in the thyroid of transgenic mice.

HRAS GNAS

3.06e-05219329167944
Pubmed

A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction.

LAMB2 LAMC1

3.06e-05219322922051
Pubmed

Twist1- and Twist2-haploinsufficiency results in reduced bone formation.

TWIST1 TWIST2

3.06e-052193224971743
Pubmed

TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer.

TWIST1 TWIST2

3.06e-052193225528769
Pubmed

Human Dermo-1 has attributes similar to twist in early bone development.

TWIST1 TWIST2

3.06e-052193211062344
Pubmed

Regulation of dendritic spines, spatial memory, and embryonic development by the TANC family of PSD-95-interacting proteins.

TANC2 TANC1

3.06e-052193221068316
Pubmed

It takes two to Twist.

TWIST1 TWIST2

3.06e-052193219644484
Pubmed

Inhibition of p53/p21 by TWIST alleviates TNF-α induced nucleus pulposus cell senescence in vitro.

TWIST1 TWIST2

3.06e-052193233378011
Pubmed

Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer.

ACOX3 HSD17B4

3.06e-052193215599942
Pubmed

DAL-1/4.1B promotes the uptake of exosomes in lung cancer cells via Heparan Sulfate Proteoglycan 2 (HSPG2).

EPB41L3 HSPG2

3.06e-052193234657240
Pubmed

Epistasis between the HSD17B4 and TG polymorphisms is associated with premature ovarian failure.

HSD17B4 TG

3.06e-052193222265031
Pubmed

Cloning and characterization of a basic helix-loop-helix protein expressed in early mesoderm and the developing somites.

TWIST1 TCF15

3.06e-05219328041747
Pubmed

Identification of a novel putative Ran-binding protein and its close homologue.

RANBP17 XPO7

3.06e-052193211071879
Pubmed

Mesenchymal Cell-Specific MyD88 Signaling Promotes Systemic Dissemination of Salmonella Typhimurium via Inflammatory Monocytes.

MYD88 TWIST2

3.06e-052193228674182
Pubmed

Cyclosporine A protects podocytes by regulating WAVE1 phosphorylation.

SYNPO WASF1

3.06e-052193226634693
Pubmed

Possible involvement of TWIST in enhanced peritoneal metastasis of epithelial ovarian carcinoma.

TWIST1 TWIST2

3.06e-052193217487558
Pubmed

PEX11 promotes peroxisome division independently of peroxisome metabolism.

PEX11B PEX11A

3.06e-052193211839773
Pubmed

The locations of the H-twist and H-dermo-1 genes are distinct on the human genome.

TWIST1 TWIST2

3.06e-05219329061034
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

EPPK1 GCN1 HSPG2 POLR1A LAMB2 LAMC1 CHD8 NCAPH

3.31e-05219193831353912
Pubmed

The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.

ITGA6 LAMB2 LAMC1

4.62e-0513193336350252
Pubmed

Basement membranes in skin are differently affected by lack of nidogen 1 and 2.

ITGA6 HSPG2 LAMC1

4.62e-0513193318356808
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

HSPG2 LAMB2 LAMC1

4.62e-0513193312682087
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

PSMB2 PRRC2C AFG3L2 UGDH GNAS HSD17B4 HECTD1 GCN1 VARS1 POLR1A DDI2 CHD8

4.85e-055341931235032548
Pubmed

Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice.

STOML1 LRBA CTSO CDH18

5.26e-0537193416707424
Pubmed

SOX9 modulates the expression of key transcription factors required for heart valve development.

TWIST1 HAND2 TWIST2

5.85e-0514193326525672
Pubmed

Basement membrane attachment is dispensable for radial glial cell fate and for proliferation, but affects positioning of neuronal subtypes.

ITGA6 HSPG2 LAMC1

5.85e-0514193316873583
Pubmed

Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation.

NCAPD2 HECTD1 NCAPH

5.85e-0514193326166704
Pubmed

Diabetic modifier QTLs identified in F2 intercrosses between Akita and A/J mice.

ADCY8 ITPR1 TG

5.85e-0514193316964447
Pubmed

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.

MYD88 CYP1A2 TRADD TWIST1 CCN5 HOXD13 HSD17B4 TWIST2 LRP6 LTBP2

6.12e-053831931019453261
Pubmed

A high-resolution molecular atlas of the fetal mouse lower urogenital tract.

ITGA6 TWIST1 DNMT1 TWIST2 LRP6

6.29e-0575193521905163
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

PSMB2 CUL9 EPB41L3 PTPN13 GNAS GCN1 LAMB2 LAMC1 ATM

6.89e-05313193938270169
Pubmed

Basement membrane composition in the early mouse embryo day 7.

HSPG2 LAMB2 LAMC1

7.29e-0515193315895400
Pubmed

The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.

IFRD2 RBM6 HYAL2

7.29e-0515193311085536
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

ITPR1 PRRC2C AFG3L2 UGDH TIMELESS HSD17B4 PLXNB1 DNMT1 DHX16 POLRMT CHD8 TANC1 CDC25B

7.68e-056501931338777146
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

EPPK1 MYO1C EXOSC6 NCAPD2 GCN1 VARS1 DNMT1 UFL1 NCAPH ELL

8.57e-053991931037536630
Pubmed

Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.

ITGA6 HSPG2 LAMB2

8.93e-0516193317948866
Pubmed

Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin.

HOXD13 HAND2 TWIST2

8.93e-0516193326001200
Pubmed

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.

ITGA6 LAMB2 LAMC1

8.93e-0516193317601529
Pubmed

Twist mediates suppression of inflammation by type I IFNs and Axl.

TWIST1 TWIST2

9.16e-053193216831897
Pubmed

Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence.

TWIST1 TWIST2

9.16e-053193218598946
Pubmed

Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance.

HAND2 NELFCD

9.16e-053193220298567
Pubmed

UFL1 promotes histone H4 ufmylation and ATM activation.

UFL1 ATM

9.16e-053193230886146
Pubmed

Characterization of three novel human cadherin genes (CDH7, CDH19, and CDH20) clustered on chromosome 18q22-q23 and with high homology to chicken cadherin-7.

CDH20 CDH7

9.16e-053193210995570
Pubmed

The basic helix loop helix transcription factor Twist1 is a novel regulator of ATF4 in osteoblasts.

TWIST1 TWIST2

9.16e-053193221866569
Pubmed

Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity.

TWIST1 TWIST2

9.16e-053193212553906
Pubmed

Human beta 2 chain of laminin (formerly S chain): cDNA cloning, chromosomal localization, and expression in carcinomas.

LAMB2 LAMC1

9.16e-05319327698745
Pubmed

Phosphorylation of the Twist1-family basic helix-loop-helix transcription factors is involved in pathological cardiac remodeling.

TWIST1 HAND2

9.16e-053193221559426
Pubmed

Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix.

LAMB2 LAMC1

9.16e-05319326209134
Pubmed

Molecular mechanism of SLC5A8 inactivation in breast cancer.

HRAS DNMT1

9.16e-053193223918800
Pubmed

The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation.

PTPN13 CAPN2

9.16e-053193228924170
Pubmed

Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli.

PEX11B PEX11A

9.16e-05319329792670
Pubmed

Tanc1/2 TPR domain interacts with Myo18a C-terminus and undergoes liquid-liquid phase separation.

TANC2 TANC1

9.16e-053193238092135
Pubmed

Oocytes progress beyond prophase in the presence of DNA damage.

ATM CDC25B

9.16e-053193222578416
Pubmed

Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control.

TIMELESS ATM

9.16e-053193219996108
Pubmed

Quercetin protects against ox‑LDL‑induced injury via regulation of ABCAl, LXR‑α and PCSK9 in RAW264.7 macrophages.

PCSK9 NR1H3

9.16e-053193229845234
Pubmed

Identification of RANBP16 and RANBP17 as novel interaction partners for the bHLH transcription factor E12.

RANBP17 XPO7

9.16e-053193220503194
Pubmed

Laminin-121--recombinant expression and interactions with integrins.

LAMB2 LAMC1

9.16e-053193220566382
Pubmed

Mapping of the binding of platelet-derived growth factor to distinct domains of the basement membrane proteins BM-40 and perlecan and distinction from the BM-40 collagen-binding epitope.

PDGFB HSPG2

9.16e-05319329692901
Pubmed

PEX11alpha is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferation.

PEX11B PEX11A

9.16e-053193212417726
Pubmed

LncRNA FAM83H-AS1 inhibits ferroptosis of endometrial cancer by promoting DNMT1-mediated CDO1 promoter hypermethylation.

IQANK1 DNMT1

9.16e-053193239159808
Pubmed

Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses.

MYD88 TRADD

9.16e-053193218641654
Pubmed

The chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability.

CHD8 ATM

9.16e-053193234292326
Pubmed

Twist1 and Twist2 Contribute to Cytokine Downregulation following Chronic NOD2 Stimulation of Human Macrophages through the Coordinated Regulation of Transcriptional Repressors and Activators.

TWIST1 TWIST2

9.16e-053193226019273
Pubmed

Mutations within helix I of Twist1 result in distinct limb defects and variation of DNA binding affinities.

TWIST1 HAND2

9.16e-053193217652084
Pubmed

Laminin-11.

LAMB2 LAMC1

9.16e-053193210481268
Pubmed

ATM-mediated ELL phosphorylation enhances its self-association through increased EAF1 interaction and inhibits global transcription during genotoxic stress.

ATM ELL

9.16e-053193236305813
Pubmed

Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide.

GNAS NELFCD

9.16e-053193223753411
Pubmed

Dermo-1: a novel twist-related bHLH protein expressed in the developing dermis.

TWIST1 TWIST2

9.16e-05319327589808
Pubmed

EMP3 is induced by TWIST1/2 and regulates epithelial-to-mesenchymal transition of gastric cancer cells.

TWIST1 TWIST2

9.16e-053193228718375
InteractionTCF4 interactions

EPB41L3 TWIST1 TCF24 HRAS WASF1 VARS1 HAND2 TCF15 POLR1A TWIST2 TCF23 RNF6 FLAD1

6.31e-0630119113int:TCF4
Cytoband3p21.3

UCN2 IFRD2 RBM6 HYAL2

1.15e-045919343p21.3
CytobandEnsembl 112 genes in cytogenetic band chr16q22

TRADD FCSK SLC7A6OS EXOSC6 PLEKHG4 ZFHX3

1.32e-041831936chr16q22
Cytoband5p14.3

CDH12 CDH18

3.64e-04719325p14.3
CytobandEnsembl 112 genes in cytogenetic band chr3p21

UCN2 IFRD2 PLXNB1 LAMB2 CELSR3 RBM6 HYAL2

4.08e-043161937chr3p21
CytobandXp22.13

NHS BEND2

4.84e-0481932Xp22.13
GeneFamilyCD molecules|Type II classical cadherins

CDH20 CDH7 CDH12 CDH18

1.68e-061312941186
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R12B SFI1 PPP1R15A ITPR1 CDCA2 PHRF1 AKAP9 ELL

4.70e-051811298694
GeneFamilyBasic helix-loop-helix proteins

TWIST1 TCF24 HAND2 TCF15 TWIST2 TCF23

1.37e-041101296420
CoexpressionAIZARANI_LIVER_C10_MVECS_1

PLVAP MYO1C PDGFB HLA-E ITGA6 SYNPO SHROOM4 GNAS LAMB2 YBX3 MMRN2 HYAL2

7.68e-0726919212M39114
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3

TANC2 JPH4 SYNPO PPP1R15A EPB41L3 HSPA12B ADCY8 TWIST1 EXOSC6 DISP3 NHS HAND2 SLC66A2 POLRMT TWIST2 NCAPH VPS9D1 DCHS1 ANKRD24 LRBA CDH18

2.31e-0583419221Facebase_RNAseq_e10.5_Mandibular Arch_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#1

PPP1R15A TWIST1 EXOSC6 DISP3 HAND2 POLRMT TWIST2 LRBA

3.57e-051371928Facebase_RNAseq_e10.5_Mandibular Arch_500_K1
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PLVAP ITGA6 RNF157 SHROOM4 MOCS1 HSPG2 TCF15 LAMC1 ARHGEF15 MMRN2 TANC1

6.05e-1018619311a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JPH4 PLVAP HLA-E SYNPO HSPA12B PLCB4 HSPG2 ARHGEF15 MMRN2 CDH7 HYAL2

9.45e-1019419311b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-tip_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PLVAP PDGFB ITGA6 HSPA12B SHROOM4 HSPG2 TCF15 LAMC1 ARHGEF15 MMRN2 HYAL2

1.11e-0919719311b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCell343B-Endothelial_cells|343B / Donor, Lineage, Cell class and subclass (all cells)

PLVAP HLA-E ITGA6 HSPA12B SHROOM4 HSPG2 COX7A1 ARHGEF15 DCHS1 MMRN2 HYAL2

1.17e-0919819311fab32347580c7a81ef1fe4fe7b325d9105a947d9
ToppCelltumor_Lung-Endothelial_cells-Tumor_ECs|tumor_Lung / Location, Cell class and cell subclass

PLVAP ITGA6 SYNPO HSPA12B PLCB4 HSPG2 COX7A1 ARHGEF15 DCHS1 MMRN2 HYAL2

1.17e-09198193115228c4bf2513186140c2c4eaa67a268c732bdc84
ToppCellmetastatic_Brain-Endothelial_cells|metastatic_Brain / Location, Cell class and cell subclass

PLVAP PDGFB ITGA6 HSPA12B SHROOM4 HSPG2 COX7A1 ARHGEF15 DCHS1 MMRN2 HYAL2

1.17e-091981931197ef7946ef11ac93318c1dd46b548dc01e5a6aba
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLVAP PDGFB HLA-E ITGA6 HSPA12B SHROOM4 HSPG2 COX7A1 ARHGEF15 DCHS1 HYAL2

1.17e-09198193110c8ec287500c58938ecc0dbbbc5f6c7a48733fc6
ToppCellmetastatic_Brain-Endothelial_cells-Tumor_ECs|metastatic_Brain / Location, Cell class and cell subclass

PLVAP PDGFB ITGA6 HSPA12B SHROOM4 HSPG2 COX7A1 ARHGEF15 DCHS1 MMRN2 HYAL2

1.17e-09198193115e274f29cc796dae7d64d6035e904816c25f9914
ToppCellBiopsy_Other_PF-Endothelial|Biopsy_Other_PF / Sample group, Lineage and Cell type

PLVAP PDGFB ITGA6 HSPA12B SHROOM4 HSPG2 COX7A1 ARHGEF15 CNKSR3 MMRN2 HYAL2

1.30e-0920019311f9916134486fb1dac55f5e7e8deb35e7a3b85770
ToppCellBiopsy_IPF-Endothelial-Endothelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

PLVAP PDGFB ITGA6 HSPA12B SHROOM4 HSPG2 COX7A1 ARHGEF15 DCHS1 MMRN2 HYAL2

1.30e-092001931139b4faad5700b3108f851f0df7fea3d298514465
ToppCellBiopsy_Other_PF-Endothelial-Endothelial_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

PLVAP PDGFB ITGA6 HSPA12B SHROOM4 HSPG2 COX7A1 ARHGEF15 CNKSR3 MMRN2 HYAL2

1.30e-092001931140d57a383c79d3365e033d08efd9371f0bc5bf55
ToppCellBiopsy_IPF-Endothelial|Biopsy_IPF / Sample group, Lineage and Cell type

PLVAP PDGFB ITGA6 HSPA12B SHROOM4 HSPG2 COX7A1 ARHGEF15 DCHS1 MMRN2 HYAL2

1.30e-09200193117ccd3b617838b39da814278dc0e12384013401ce
ToppCellCOPD-Endothelial-VE_Peribronchial|COPD / Disease state, Lineage and Cell class

PLVAP SHROOM4 PLCB4 HSPG2 COX7A1 ARHGEF15 CNKSR3 MMRN2 TANC1 HYAL2

9.27e-091861931023c7d0e8372a71546d687278b985f761d282f92f
ToppCellEndothelial-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

PLVAP HSPA12B SHROOM4 PLCB4 HSPG2 COX7A1 ARHGEF15 DCHS1 MMRN2 HYAL2

1.19e-0819119310f702dfe88a9b04091dae87df61b2b4f43525f86a
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLVAP PDGFB HLA-E SYNPO HSPA12B SHROOM4 HSPG2 ARHGEF15 MMRN2 HYAL2

1.19e-081911931004c7aa2e39fdd08ca24c10d43b29a5e41a73b9e0
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLVAP PDGFB HLA-E SYNPO HSPA12B SHROOM4 HSPG2 ARHGEF15 MMRN2 HYAL2

1.19e-0819119310db8dd6bbba803585bdd6a55d5c403d383f2e9acf
ToppCellIPF-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

PLVAP SHROOM4 PLCB4 HSPG2 COX7A1 ARHGEF15 CNKSR3 MMRN2 TANC1 HYAL2

1.32e-0819319310ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCellEndothelial-A-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PLVAP SYNPO HSPA12B PLCB4 HSPG2 TCF15 COX7A1 ARHGEF15 DCHS1 MMRN2

1.39e-0819419310e656ac5539e59e321b46706cb8cc423b2c3358a0
ToppCellIPF-Endothelial|IPF / Disease state, Lineage and Cell class

PLVAP SHROOM4 PLCB4 HSPG2 COX7A1 ARHGEF15 CNKSR3 MMRN2 TANC1 HYAL2

1.39e-08194193109591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCellEndothelial-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

PLVAP PDGFB SYNPO HSPA12B SHROOM4 COX7A1 ARHGEF15 DCHS1 MMRN2 HYAL2

1.46e-0819519310c3a0aa34b672c99cb3a2a4e9218412dbd19da3ca
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLVAP PDGFB HLA-E ITGA6 HSPA12B SHROOM4 HSPG2 ARHGEF15 MMRN2 HYAL2

1.60e-081971931015d1e0dffee8f5ba8cee37adfbfa0551a0cd5e15
ToppCell390C-Endothelial_cells|390C / Donor, Lineage, Cell class and subclass (all cells)

PLVAP SYNPO HSPA12B HSPG2 COX7A1 ARHGEF15 CNKSR3 DCHS1 MMRN2 HYAL2

1.60e-0819719310aa381acea0f7882d39435a6f713386bf0588b5f8
ToppCell390C-Endothelial_cells-Endothelial-A_(Artery)-|390C / Donor, Lineage, Cell class and subclass (all cells)

PLVAP PDGFB SYNPO HSPA12B HSPG2 ARHGEF15 CNKSR3 DCHS1 MMRN2 HYAL2

1.68e-0819819310f83956c4b13b5d0a0c6e3d9f580dbf99649ef175
ToppCell(6)_Endothelial_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PLVAP ITGA6 HSPA12B SHROOM4 HSPG2 COX7A1 ARHGEF15 CNKSR3 MMRN2 HYAL2

1.68e-0819819310f38f49d532fa6211f57e36ee494478bdd3f4f89c
ToppCell10x3'2.3-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PLVAP PDGFB ITGA6 HSPA12B HSPG2 TCF15 ARHGEF15 DCHS1 MMRN2 HYAL2

1.68e-08198193102630a7a6e56febe5c0b0bde70dd7292fa1650c47
ToppCell(6)_Endothelial-A_(Artery)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PLVAP ITGA6 HSPA12B SHROOM4 PLCB4 HSPG2 ARHGEF15 CNKSR3 MMRN2 HYAL2

1.68e-081981931044f8cd5afa3685dcc8bfea0b15af5e8817e12e2e
ToppCell10x3'2.3-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PLVAP PDGFB ITGA6 HSPA12B HSPG2 TCF15 ARHGEF15 DCHS1 MMRN2 HYAL2

1.68e-08198193101e83bec16dcd60460422625f89952ff506d6be51
ToppCell390C-Endothelial_cells-Endothelial-A_(Artery)|390C / Donor, Lineage, Cell class and subclass (all cells)

PLVAP PDGFB SYNPO HSPA12B HSPG2 ARHGEF15 CNKSR3 DCHS1 MMRN2 HYAL2

1.68e-08198193105b5ccce5de82ea041465e656147cec3b8beb865b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP PDGFB SYNPO HSPA12B HSPG2 TCF15 ARHGEF15 DCHS1 MMRN2 HYAL2

1.77e-0819919310da5a88749d859d535daa030d0974485906cc0ba7
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-tip_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PLVAP ITGA6 SYNPO SHROOM4 HSPG2 LAMC1 SHROOM2 ARHGEF15 MMRN2 HYAL2

1.77e-08199193101c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCellParenchymal-10x5prime-Endothelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PLVAP ITGA6 HSPA12B SHROOM4 HSPG2 COX7A1 ARHGEF15 CNKSR3 MMRN2 HYAL2

1.85e-08200193100e648e9eb96c83a94505d07323785a7a40997eb0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP PDGFB HLA-E HSPA12B HSPG2 TCF15 ARHGEF15 DCHS1 MMRN2 HYAL2

1.85e-0820019310b1be27d134a8633e3e7862c6a0d7be2001d387f0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP PDGFB HLA-E SYNPO HSPA12B HSPG2 ARHGEF15 DCHS1 MMRN2 HYAL2

1.85e-08200193102e47888e041ec3d265425d1df97b6665c6da889c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP PDGFB HLA-E SYNPO HSPA12B HSPG2 ARHGEF15 DCHS1 MMRN2 HYAL2

1.85e-082001931050fa0f8a3e490d5941b34e66a10158eba6c909d4
ToppCellEndothelial-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

PLVAP PDGFB ITGA6 HSPG2 COX7A1 ARHGEF15 DCHS1 MMRN2 HYAL2

1.11e-0718319392c3f2c25c38f0598b4787d2ec335efe00fdc9751
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLVAP PDGFB HSPA12B SHROOM4 TCF15 YBX3 ARHGEF15 MMRN2 HYAL2

1.17e-071841939842473fa415575441b595073a994b6d621169776
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

PLVAP ITGA6 SHROOM4 PLCB4 HSPG2 COX7A1 ARHGEF15 MMRN2 HYAL2

1.28e-0718619392e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

PLVAP ITGA6 SHROOM4 PLCB4 HSPG2 COX7A1 ARHGEF15 MMRN2 HYAL2

1.28e-071861939c3449e54454009973818fc1101933c6f0168258c
ToppCellControl-Endothelial-VE_Peribronchial|Control / Disease state, Lineage and Cell class

PLVAP SHROOM4 PLCB4 HSPG2 COX7A1 ARHGEF15 CNKSR3 MMRN2 TANC1

1.40e-071881939f5b7dbc89f992c13280d36a34935be83906b1bc0
ToppCellControl-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

PLVAP SHROOM4 PLCB4 HSPG2 COX7A1 ARHGEF15 CNKSR3 MMRN2 TANC1

1.47e-071891939c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCellEndothelial-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

PLVAP PDGFB PLCB4 HSPG2 COX7A1 ARHGEF15 DCHS1 MMRN2 HYAL2

1.47e-07189193904b565855f58ca0f343904d04be657b66e109076
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JPH4 PDGFB SYNPO HSPA12B PLCB4 HSPG2 ARHGEF15 MMRN2 CDH7

1.47e-07189193912b6f1c3bf526b90e112374bf937701f645c5780
ToppCell3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLVAP PDGFB SYNPO HSPA12B SHROOM4 HSPG2 ARHGEF15 MMRN2 HYAL2

1.53e-071901939ec6b8e2852e1cce0217ff61243defe98b2351640
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFB SYNPO HSPA12B SHROOM4 PLCB4 HSPG2 YBX3 ARHGEF15 MMRN2

1.60e-071911939adb2e3efcad02889d8229325080da5e7830fd3ae
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLVAP ITGA6 PLCB4 HSPG2 YBX3 CNKSR3 MMRN2 CDH7 HYAL2

1.68e-07192193981baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFB HLA-E SYNPO HSPA12B PLCB4 HSPG2 ARHGEF15 MMRN2 HYAL2

1.68e-07192193956b021c297a21dff357531f21e2464f85186106d
ToppCell10x5'v1-week_14-16-Endothelial-stroma-proliferating_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PLVAP SYNPO HSPG2 SHROOM2 ARHGEF15 GPR161 DCHS1 MMRN2 HYAL2

1.83e-0719419398a4be91414a2e69dd410aa75791f16008204c9a1
ToppCellIPF-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

PLVAP SHROOM4 PLCB4 HSPG2 ARHGEF15 CNKSR3 MMRN2 TANC1 HYAL2

1.91e-071951939120296531bbc8080dcabacbd64733cc1dc34603a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLVAP PDGFB ITGA6 HSPA12B SHROOM4 HSPG2 LAMC1 MMRN2 HYAL2

1.91e-0719519394658fb197657d7692ee344ae76b11b0210c418ba
ToppCellIPF-Endothelial-VE_Peribronchial|IPF / Disease state, Lineage and Cell class

PLVAP SHROOM4 PLCB4 HSPG2 ARHGEF15 CNKSR3 MMRN2 TANC1 HYAL2

1.91e-0719519392c3ad3cb79f11119ac69c413a938d21199145040
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PDGFB HSPA12B SHROOM4 PLCB4 HSPG2 ARHGEF15 MMRN2 LRP6 HYAL2

1.91e-071951939a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCellEndothelial|World / shred by cell class for bronchial biopsy

PLVAP PDGFB HLA-E ITGA6 HSPG2 ARHGEF15 DCHS1 MMRN2 CDH18

1.91e-071951939f0e46e859f7a9bdead3203889f7e20fa21f76ff0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP PDGFB HLA-E HSPA12B PLCB4 HSPG2 ARHGEF15 MMRN2 HYAL2

1.91e-07195193977e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCellfacs-GAT-Fat-3m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP PDGFB ITGA6 SYNPO HSPA12B TCF15 ARHGEF15 MMRN2 TANC1

2.00e-071961939b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCellfacs-GAT-Fat-3m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP PDGFB ITGA6 SYNPO HSPA12B TCF15 ARHGEF15 MMRN2 TANC1

2.00e-071961939ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCellfacs-GAT-Fat-3m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP PDGFB ITGA6 SYNPO HSPA12B TCF15 ARHGEF15 MMRN2 TANC1

2.00e-071961939039044ab28c53391c34d8226fb8cf78549e63ef4
ToppCelltumor_Lung-Endothelial_cells|tumor_Lung / Location, Cell class and cell subclass

PLVAP ITGA6 HSPA12B HSPG2 COX7A1 ARHGEF15 DCHS1 MMRN2 HYAL2

2.09e-0719719396870b311c54a73723768276a58456620f5217d43
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VWA5B2 EPPK1 SHROOM4 HSPG2 COX7A1 LAMC1 ARHGEF15 RANBP17 MMRN2

2.09e-071971939a312d9cf4ced949307eb9620be4eed926300b892
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

PLVAP ITGA6 HSPA12B SHROOM4 HSPG2 ARHGEF15 CNKSR3 MMRN2 HYAL2

2.09e-0719719397caa2c86dc4d50b57a7db8f7278d1588282ad6db
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Endothelial-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PLVAP ITGA6 SHROOM4 HSPG2 ARHGEF15 CNKSR3 MMRN2 CDH7 HYAL2

2.09e-071971939f969685dee212f33a6f09e54c0cd1fd24ffef546
ToppCell368C-Endothelial_cells-Endothelial-A_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

PLVAP ITGA6 HSPA12B SHROOM4 HSPG2 ARHGEF15 CNKSR3 MMRN2 HYAL2

2.09e-071971939951f18f326967206adbbfc422cce9eea3d2e0854
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLVAP PDGFB SHROOM4 PLCB4 HSPG2 YBX3 ARHGEF15 MMRN2 HYAL2

2.09e-071971939e8e879b7634a29569061d3515d180784094a31e7
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PLVAP ITGA6 SHROOM4 HSPG2 ARHGEF15 CNKSR3 MMRN2 CDH7 HYAL2

2.09e-0719719391a137af40697137bb9d2b5caf2b1ffda55f04461
ToppCell356C-Endothelial_cells|356C / Donor, Lineage, Cell class and subclass (all cells)

PLVAP ITGA6 HSPA12B HSPG2 COX7A1 ARHGEF15 CNKSR3 MMRN2 HYAL2

2.09e-071971939f20eda534b2b28986790b28ce150ca3ba067593a
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PLVAP PDGFB ITGA6 HSPA12B SHROOM4 HSPG2 ARHGEF15 MMRN2 HYAL2

2.09e-0719719399b3d6fe76dd7d61a286a28d9466b5f2fece048e1
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDGFB HLA-E ITGA6 HSPA12B SHROOM4 COX7A1 ARHGEF15 MMRN2 HYAL2

2.09e-071971939ca6bce1a92c6326f41a6300c31da02386bafa152
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLVAP ITGA6 SHROOM4 HSPG2 ARHGEF15 CNKSR3 MMRN2 CDH7 HYAL2

2.09e-07197193996d63a8d00583e2aa0a38412e2ae27e23f399493
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPPK1 ITGA6 CBLC PHLDA2 TWIST1 UGDH HRAS SGPP2 YBX3

2.18e-07198193977517df37dc894c78ef1e2b24dd7ba31f928bdb7
ToppCell18-Airway-Endothelial-Endothelial|Airway / Age, Tissue, Lineage and Cell class

PLVAP PDGFB HLA-E ITGA6 HSPA12B HSPG2 ARHGEF15 MMRN2 HYAL2

2.18e-07198193970d3ea0837dd6ad62abdf349e566a2e62c8e345a
ToppCell18-Distal-Endothelial-Endothelial|Distal / Age, Tissue, Lineage and Cell class

PLVAP PDGFB HLA-E ITGA6 HSPA12B HSPG2 ARHGEF15 MMRN2 HYAL2

2.18e-071981939efd3af3c0b4ab29605331ecdcb7a52cba38e6028
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLVAP PDGFB ITGA6 SYNPO HSPA12B HSPG2 ARHGEF15 MMRN2 HYAL2

2.18e-071981939e9e98c20ff7b3f3851db86381550ce7085e2db9e
ToppCell18-Distal-Endothelial|Distal / Age, Tissue, Lineage and Cell class

PLVAP PDGFB HLA-E ITGA6 HSPA12B HSPG2 ARHGEF15 MMRN2 HYAL2

2.18e-071981939ee657a84928d54eb7a9a66c7acb19a7c119d6423
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-intermediate_cap|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PDGFB ITGA6 HSPA12B SHROOM4 HSPG2 TCF15 ARHGEF15 MMRN2 HYAL2

2.18e-071981939a75499f8f1630359b64717c300621aa3b1ab44d4
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Endothelial|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

PLVAP SHROOM4 PLCB4 HSPG2 COX7A1 ARHGEF15 CNKSR3 MMRN2 HYAL2

2.18e-071981939531b0f88c95f813e3914c96749f591e80ca321d0
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDGFB HLA-E ITGA6 HSPA12B SHROOM4 COX7A1 ARHGEF15 MMRN2 HYAL2

2.18e-0719819392400f8b8c51739ea2ae2b9f24f44eaeefa2bb6fc
ToppCell18-Airway-Endothelial|Airway / Age, Tissue, Lineage and Cell class

PLVAP PDGFB HLA-E ITGA6 HSPA12B HSPG2 ARHGEF15 MMRN2 HYAL2

2.18e-0719819396b7f1b352dc3a803af87106ffb63944bd4286dfe
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLVAP PDGFB HLA-E ITGA6 HSPG2 TCF15 ARHGEF15 MMRN2 HYAL2

2.18e-071981939f7a957e8f09d54a55a5dbecfaa9cdf01e6fd543d
ToppCell367C-Endothelial_cells|367C / Donor, Lineage, Cell class and subclass (all cells)

PLVAP ITGA6 HSPA12B SHROOM4 HSPG2 ARHGEF15 CNKSR3 MMRN2 HYAL2

2.27e-071991939636ff80938907f137e955388797072ab45289062
ToppCellControl_saline|World / Treatment groups by lineage, cell group, cell type

PDGFB HSPA12B PLCB4 GNAS CAPN2 LAMB2 ARHGEF15 TANC1 HYAL2

2.27e-07199193911c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP HLA-E HSPA12B HSPG2 TCF15 ARHGEF15 DCHS1 MMRN2 HYAL2

2.27e-0719919398b62d43af8b2ebb4c1b2d068d50beaf35728dbe7
ToppCellILEUM-inflamed-(7)_ACKR1+_endothelial_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PLVAP SYNPO HSPA12B SHROOM4 HSPG2 COX7A1 ARHGEF15 MMRN2 HYAL2

2.27e-0719919395c799115a6e95bcd896e4ad10bd272705c9a4e2c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP HLA-E SYNPO HSPA12B HSPG2 ARHGEF15 DCHS1 MMRN2 HYAL2

2.27e-071991939f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCell3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLVAP ITGA6 SYNPO HSPA12B HSPG2 COX7A1 ARHGEF15 MMRN2 HYAL2

2.27e-07199193957709dc893da8d9333830b8277a6d92e25aa8bc0
ToppCellnormal_Lung-Endothelial_cells-Tip-like_ECs|normal_Lung / Location, Cell class and cell subclass

PLVAP HLA-E ITGA6 HSPA12B SHROOM4 COX7A1 ARHGEF15 MMRN2 HYAL2

2.27e-0719919391ae0b47fade7b1cd74c0faabcf4f12f56f62264e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP PDGFB HLA-E SYNPO HSPA12B HSPG2 ARHGEF15 MMRN2 HYAL2

2.27e-07199193933f1669eeb701986b4dec409efdb6c06c3c41c2b
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_venous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PLVAP SHROOM4 PLCB4 HSPG2 COX7A1 ARHGEF15 CNKSR3 MMRN2 HYAL2

2.37e-072001939cb00760ae75c30b1cb8526534aabd4ffc7c21000
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLVAP HLA-E ITGA6 SYNPO HSPG2 TCF15 ARHGEF15 MMRN2 HYAL2

2.37e-072001939ae6cc5462a8a254682793fb8cc348b9721c729bf
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLVAP PDGFB HLA-E ITGA6 HSPG2 TCF15 ARHGEF15 MMRN2 HYAL2

2.37e-0720019399e44da8aaac239ed69d674dcd53800c5eaf397cb
ToppCellParenchyma_COVID-19-Endothelial-TX|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PLVAP PDGFB ITGA6 SHROOM4 HSPG2 ARHGEF15 CNKSR3 MMRN2 HYAL2

2.37e-072001939abcbd5a156aa4fd51d284441388975c81c0b88ae
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MYO7B ITGA6 HSPA12B SHROOM4 HSPG2 YBX3 ARHGEF15 GAS2L1 MMRN2

2.37e-072001939a8b59e6fe04271fef61db911a286b5c48438bb84
ToppCellILEUM-non-inflamed-(7)_CD36+_endothelial_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PLVAP ITGA6 SYNPO HSPA12B HSPG2 COX7A1 ARHGEF15 MMRN2 HYAL2

2.37e-07200193945755a597725015dc3ee36f9166f9e82f6f9c603
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Artery|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDGFB ITGA6 HSPA12B PLCB4 GNAS YBX3 ARHGEF15 MMRN2 HYAL2

2.37e-07200193977ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCellLung_Parenchyma-Severe-Endothelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PLVAP PDGFB ITGA6 SHROOM4 HSPG2 ARHGEF15 CNKSR3 MMRN2 HYAL2

2.37e-072001939d9d0ffa18e5b4647966e19ad9830cbba6120677e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP PDGFB HLA-E HSPA12B HSPG2 ARHGEF15 DCHS1 MMRN2 HYAL2

2.37e-072001939dba96cda5f3b780a3d4171b61bc8aaddc1f5d466
ToppCellBiopsy_Control_(H.)-Endothelial|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

PLVAP HLA-E ITGA6 HSPA12B SHROOM4 COX7A1 ARHGEF15 MMRN2 HYAL2

2.37e-0720019396a9b6a4b4f204598290ae21c87ddb42ac95dfc4c
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PLVAP ITGA6 SYNPO HSPA12B HSPG2 COX7A1 ARHGEF15 MMRN2 HYAL2

2.37e-072001939ec92fe4eafe527d351ee73c9735e96855ac506a3
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PLVAP PDGFB ITGA6 SHROOM4 HSPG2 ARHGEF15 CNKSR3 MMRN2 HYAL2

2.37e-072001939e9d5ba140cabae11c437012d519b85f5412dcc94
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP PDGFB HLA-E HSPA12B HSPG2 ARHGEF15 DCHS1 MMRN2 HYAL2

2.37e-072001939ced14d83222dbebca85c40540e76824e683354f3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP PDGFB HLA-E HSPA12B HSPG2 ARHGEF15 DCHS1 MMRN2 HYAL2

2.37e-0720019397a69ad5b6c84f1aebacea5cacb9bc5c63dfd1dac
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / Treatment groups by lineage, cell group, cell type

PDGFB ITGA6 HSPA12B PLCB4 GNAS LAMB2 YBX3 ARHGEF15 HYAL2

2.37e-072001939b17eb1587ca86c3d40515128a00a8d8fd787fccf
DiseaseSaethre-Chotzen syndrome (implicated_via_orthology)

TWIST1 TWIST2

4.04e-0521882DOID:14768 (implicated_via_orthology)
Diseaseobesity (implicated_via_orthology)

ITPR1 HSD17B4 PLXNB1 CAPN2 DCHS1 ZFHX2 ZFHX3 HRH3

7.56e-052151888DOID:9970 (implicated_via_orthology)
Diseaseblood phosphate measurement

CYP1A2 HSPG2 SGPP2 ZFHX3 ANKRD24 ELL CUX1

1.32e-041741887EFO_0010972
DiseaseZellweger Syndrome

PEX11B PEX11A HSD17B4

1.34e-04161883C0043459
Diseaseleukemia (implicated_via_orthology)

ASH1L HRAS ATM

2.29e-04191883DOID:1240 (implicated_via_orthology)
Diseasemigraine with aura, age at onset

CUX1 CDH18

2.40e-0441882EFO_0004847, MONDO_0005475
Diseaseocular hypertension, response to triamcinolone acetonide

TIMELESS VARS1 CHD9 GRIK1

2.70e-04491884EFO_0006954, EFO_1001069
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

TANC2 ASH1L PLXNB1 TANC1

2.70e-04491884DOID:0060037 (implicated_via_orthology)
DiseaseNeurodevelopmental Disorders

TANC2 IQSEC2 ASH1L ITPR1 PLXNB1

3.29e-04931885C1535926
DiseaseAntithrombotic agent use measurement

TWIST1 PCSK9 OPRL1 ZFHX3

4.22e-04551884EFO_0009925
DiseaseWithdrawal Symptoms

ADCY8 FAAH GNAS OPRL1

5.18e-04581884C0087169
DiseaseDrug Withdrawal Symptoms

ADCY8 FAAH GNAS OPRL1

5.18e-04581884C0086189
DiseaseSubstance Withdrawal Syndrome

ADCY8 FAAH GNAS OPRL1

5.18e-04581884C0038587
DiseaseIntellectual Disability

TANC2 ASH1L PEX11B SHROOM4 FCSK GNAS WASF1 CACNA1E CHD8 KIF7

6.27e-0444718810C3714756
Diseaselung non-small cell carcinoma (is_marker_for)

MYD88 DNMT1 NCAPH ZFHX3 ATM CUX1

7.74e-041691886DOID:3908 (is_marker_for)
DiseaseCHARGE syndrome (implicated_via_orthology)

CHD9 CHD8

8.30e-0471882DOID:0050834 (implicated_via_orthology)
Diseaseduodenal ulcer, gastric ulcer

GNAS JRK

8.30e-0471882EFO_0004607, EFO_0009454
DiseaseN-palmitoylglycine measurement

FAAH DMBX1

8.30e-0471882EFO_0800342
DiseaseX-24747 measurement

ACOT4 FBF1

1.10e-0381882EFO_0022135
DiseaseVasodilators used in cardiac diseases use measurement

TWIST1 PCSK9 YBX3

1.32e-03341883EFO_0009926
Diseaseduodenal ulcer

GNAS OPRL1 JRK

1.56e-03361883EFO_0004607
DiseaseLiver carcinoma

CYP1A2 PLVAP PDGFB RNF157 CDCA2 HRAS NCAPH CELSR3 ATM HAO2

1.61e-0350718810C2239176
DiseaseNephroblastoma

NHS PCSK9

1.76e-03101882Orphanet_654
DiseaseImmature Reticulocyte Fraction Measurement

IFRD2 DNMT1

1.76e-03101882EFO_0009253
Diseaseretinal vasculature measurement

CYP1A2 PDGFB ITPR1 CDCA2 MOCS1 DHX16 HSPG2 LAMC1 LTBP2 R3HDM1

1.86e-0351718810EFO_0010554
DiseaseMacrocephaly

CACNA1E CHD8

2.14e-03111882C0221355
DiseaseMarfan Syndrome

LAMC1 LTBP2

2.14e-03111882C0024796
Diseasebreast carcinoma

ASH1L EPB41L3 ADCY8 CABLES1 ITPR1 RNF19A LAMB2 LAMC1 GRIK1 GPR161 AKAP9 CDH12 ELL CUX1 DNAH11

2.33e-03101918815EFO_0000305
Diseaseouter ear morphology trait

LRBA CUX1

2.56e-03121882EFO_0007664
Diseaseage of onset of multiple sclerosis

ITPR1 TMEM114

2.56e-03121882OBA_2001029
Diseaseautism spectrum disorder (implicated_via_orthology)

ASH1L LAMC1 CHD9 CHD8 LRBA

2.96e-031521885DOID:0060041 (implicated_via_orthology)
Diseasereticulocyte measurement

PLVAP SPTA1 ASH1L PPP1R15A MIDEAS ADCY8 CDH20 IFRD2 FBXO34 DNMT1 ARHGEF15 RBM6 ADGRD2 ELL CUX1

3.17e-03105318815EFO_0010700
DiseaseParoxysmal atrial fibrillation

MYO1C HAND2 HSPG2 ZFHX3 XPO7

3.31e-031561885C0235480
Diseasefamilial atrial fibrillation

MYO1C HAND2 HSPG2 ZFHX3 XPO7

3.31e-031561885C3468561
DiseasePersistent atrial fibrillation

MYO1C HAND2 HSPG2 ZFHX3 XPO7

3.31e-031561885C2585653
DiseaseNeuroblastoma

HRAS GNAS HAND2

3.36e-03471883C0027819
Diseasemultiple myeloma, monoclonal gammopathy

PDGFB DNAH11

3.49e-03141882EFO_0000203, EFO_0001378
DiseaseAtrial Fibrillation

MYO1C HAND2 HSPG2 ZFHX3 XPO7

3.69e-031601885C0004238
DiseaseMalignant neoplasm of breast

PPP1R12B EPB41L3 FAAH CDH20 FBXO8 HRAS NHS TIMELESS PLXNB1 DNMT1 SHROOM2 AKAP9 ATM LRBA CUX1

3.81e-03107418815C0006142
Diseaseforehead morphology measurement

GRIK1 CDH7

4.01e-03151882EFO_0007844
DiseaseNeoplasm of uncertain or unknown behavior of bladder

HRAS ATM

4.01e-03151882C0496930
Diseasecaffeine measurement

LAMB2 LAMC1

4.01e-03151882EFO_0021177
DiseaseBenign neoplasm of bladder

HRAS ATM

4.01e-03151882C0154017
DiseaseCarcinoma in situ of bladder

HRAS ATM

4.01e-03151882C0154091
DiseaseAdrenoleukodystrophy, Neonatal

PEX11B HSD17B4

4.01e-03151882C0282525
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

CDY2A CDY1

4.57e-03161882C1839071
DiseaseSpermatogenic failure, Y-linked, 2

CDY2A CDY1

4.57e-03161882cv:C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

CDY2A CDY1

4.57e-03161882415000
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

NCAPD2 NCAPH

4.57e-03161882DOID:0070296 (is_implicated_in)
Diseaseurate measurement

CYP1A2 ASH1L EPB41L3 HOXD13 GNAS VARS1 FBXO34 ATP8B3 PLPP7 GRIK1 DMBX1 RBM6 HAO2

5.03e-0389518813EFO_0004531
DiseaseLeukemia, Myelocytic, Acute

CBLC HRAS CAPN2 GAS2L1 CUX1

5.13e-031731885C0023467
Diseaserespiratory symptom change measurement, response to placebo

ADCY8 CDCA2

5.16e-03171882EFO_0008344, EFO_0010068
DiseaseCholestasis

CYP1A2 GNAS NR1H3 HAO2

5.45e-031101884C0008370
DiseaseColorectal Carcinoma

CYP1A2 ADCY8 CABLES1 GNAS SLC66A2 LAMC1 AKAP9 DCHS1 MMRN2 CDH7 CUX1

5.58e-0370218811C0009402
DiseaseCarcinoma of bladder

HRAS ATM

5.78e-03181882C0699885
Diseasesquamous cell carcinoma (is_implicated_in)

HRAS RNF6

5.78e-03181882DOID:1749 (is_implicated_in)
Diseaseimmature platelet fraction

CABLES1 GNAS NELFCD CUX1

6.18e-031141884EFO_0009187
DiseaseAlzheimer's disease (is_marker_for)

PDGFB ITPR1 HRAS GNAS CAPN2 ATM

6.25e-032571886DOID:10652 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
LSDRAQRQAFLETRR

ADCY8

341

P40145
VQRAISRRVQEAAAA

AARD

71

Q4LEZ3
ELSFSREQIQRARQT

AKAP9

536

Q99996
FSALQTARSVRTRRL

ASH1L

2416

Q9NR48
SRIFSNNARRRTSRS

CDY1

71

Q9Y6F8
SRIFSNNARRRTSRS

CDY2A

71

Q9Y6F7
ANRIVAEAIARARAR

CHD8

461

Q9HCK8
AVAANQSRARRGASR

DISP3

241

Q9P2K9
ARIERITRRFTQLDA

ELL

541

P55199
ANDELFRAGSRLRRQ

CBLC

106

Q9ULV8
VTFEDRARHRQSQRR

CACNA1E

906

Q15878
RAQARRQTIRHSTRE

DNMT1

596

P26358
LAVAIALRFSATRRQ

ACOX3

321

O15254
RFVTTQARASRNSLL

AFG3L2

41

Q9Y4W6
RRVSNARARLFRAAS

ARMC2

126

Q8NEN0
IQRINLFDSFEASRR

GRIK1

81

P39086
SLSRNNSFRRNVGRV

FBXO34

301

Q9NWN3
AARRARSFAQDARVR

DNAH11

46

Q96DT5
DTNVRFSAELRRLQS

ARHGEF15

526

O94989
RARRSSEVLQERAFV

ATP8B3

886

O60423
RTEAERARQAQSRAQ

ANKRD24

1031

Q8TF21
NFVQFRSMRRARDVR

DHX16

901

O60231
IRSFSSTARNRFQNR

COX7A1

11

P24310
FQSQSLRDRARRFEE

MTUS2

1201

Q5JR59
RRQIFRVNKDASGRS

R3HDM1

326

Q15032
AARTVESRQAQDLAR

HRAS

121

P01112
DRFTQNLSVFRRDVA

RANBP17

1056

Q9H2T7
QSTRRFRDQIRLRFD

HSPG2

531

P98160
RRRLAQNALNTFSIA

CYP1A2

136

P05177
QQQCNRRSFSDRLRV

NR1H3

221

Q13133
GFQNSEQSRRILRRR

NOL11

371

Q9H8H0
NASRRRAARVSARVF

DCHS1

1521

Q96JQ0
RSARDTAQIFRVNLR

HLA-E

86

P13747
NFVSFRVQEALRVAR

HYAL2

266

Q12891
VARDSARARASRSFQ

MAGEB17

321

A8MXT2
SAVRRIAQEVQRFAQ

NELFCD

256

Q8IXH7
RNAARRDSVLAASRD

ITPR1

1591

Q14643
RARAATSRLRSQVQA

MMRN2

556

Q9H8L6
QQSLVRAARRRGAAA

EXOSC6

256

Q5RKV6
LSRRAARTIQTAFRQ

IQSEC2

346

Q5JU85
GARRAVSAARQRQEI

JPH4

366

Q96JJ6
VSAARQRQEIAAARA

JPH4

371

Q96JJ6
RVASASADRNDQRGR

BEND2

596

Q8NDZ0
SSQRERFRARNQELE

CUX1

506

Q13948
DRASLFVARTRRSNS

CCDC120

346

Q96HB5
ARRLTSAVINEIFQR

FSIP2

5946

Q5CZC0
RSRRGRFLNQTAAAA

ITGAE

436

P38570
ISRRLIDRTNANFLV

PDGFB

106

P01127
SERTARRLQAQAARR

PCSK9

91

Q8NBP7
RRDLDRINASFRQCQ

PLVAP

106

Q9BX97
LFLRRDLQAQSRAFR

PLXNB1

231

O43157
RALRAVFRSQQQETV

JRK

516

O75564
INQRTAIRFRAAVSS

ABCC11

226

Q96J66
REFIRNTRRAAQNIS

FBXO8

286

Q9NRD0
SRLQEFRRRVAAAQS

KIF7

781

Q2M1P5
FRRRVAAAQSQVQVL

KIF7

786

Q2M1P5
TRQSERVRATVNRNR

PHRF1

276

Q9P1Y6
RVRATVNRNRISTAR

PHRF1

281

Q9P1Y6
RRLSLFLNVRTQVAA

MYD88

31

Q99836
AVNGQRRDSRSTVFR

LRBA

1291

P50851
FSRRADIRRISLETN

LRP6

636

O75581
SRIIRNEQFAIRRFQ

CDC25B

136

P30305
AFQRRAAKRRETQEA

FAM161B

381

Q96MY7
RVAETRRQASEAQQR

LAMB2

1476

P55268
YRDAASRRALQAAIQ

GCN1

61

Q92616
SRAAARFLARKLNRS

ASIC3

386

Q9UHC3
ERRKSGLSSRVQFRN

ITGA6

566

P23229
RFSRQEQRLFILESR

PCDHA5

131

Q9Y5H7
SIDSSFRQAREQLRR

HSPA12B

276

Q96MM6
AQRCRELRNFSSLRA

RGL3

331

Q3MIN7
ARAASEEVSRRRQFL

MOCS1

36

Q9NZB8
SLRNRAIQTALRNAF

OR10Z1

291

Q8NGY1
RKERRRTQSINSAFA

HAND2

106

P61296
RAAEVRTRDRATFTN

PABPC5

186

Q96DU9
ANRFQSGSRRKAAQR

KCTD18

311

Q6PI47
ATLASRRDLFFRQAL

FCSK

541

Q8N0W3
FRLNSRSARSVARLS

GAL3ST2

251

Q9H3Q3
AQTNTVSFRAADIRR

ATM

911

Q13315
RVRGNLRQAAIDRFS

CHD9

1231

Q3L8U1
RQSRRQSVSRFFADS

FBF1

301

Q8TES7
ESFVRRVANIARTNA

HECTD1

1546

Q9ULT8
NFRSVEVSRTNRELR

CCDC150

861

Q8NCX0
STSAFEQLQRSRRRL

CABLES1

271

Q8TDN4
RARRTLERVQQEAQS

CROCC2

961

H7BZ55
RDNQDNTARILTRRS

CDH20

546

Q9HBT6
QRRSRTAFTAQQLEA

DMBX1

71

Q8NFW5
ARRARSQSREEQAVL

GAS2L1

431

Q99501
VVNNAGILRDRSFAR

HSD17B4

96

P51659
ARRVLQQFADNDVSR

HSD17B4

541

P51659
EEALARRRRQTASAL

CCDC102A

386

Q96A19
RRRISAATNLSERQV

HOXD13

306

P35453
RAQQRAAAQQRRSFL

GNAS

51

O95467
VSNQNRFCRLETQRR

CCN5

216

O76076
AEARRPSRAQQSRRV

LTBP2

101

Q14767
SQSFTQRFRLSRDRK

HRH3

341

Q9Y5N1
AKADRRRQRSTFRAV

IFRD2

386

Q12894
IQSTRRRRRASQEAN

MIDEAS

451

Q6PJG2
RNVNTLRERISAFQS

CDCA2

136

Q69YH5
DNEDNTASILTRRRR

CDH18

541

Q13634
QRQRTSRLFSISNRI

GPR161

351

Q8N6U8
NLSFSFRVDRRDTRL

LAMC1

576

P11047
AREFAVNLRNRVSAI

CUL9

2306

Q8IWT3
RDFRNNTAGIETRRN

CDH12

541

P55289
RSQRLQQLTEVSRRS

ESCO1

121

Q5FWF5
TARGAVVRARQRQRA

FAAH

36

O00519
ASILTRRNGFRRQEQ

CDH7

541

Q9ULB5
FSRVLVEQQQDRARR

DDI2

171

Q5TDH0
KVTSANRARFRRAAN

CELSR3

306

Q9NYQ7
GTRLFQRQEQRSRLS

FLAD1

6

Q8NFF5
NRARERSDTFINLRE

CAPN2

456

P17655
RFSAQSQARERLCRA

PEX11B

6

O96011
ARTFSRHVVQRQRVS

POLRMT

506

O00411
RFSRPESEQARQRRV

POLR3E

176

Q9NVU0
RTQAQTRRASALIDR

EPB41L3

411

Q9Y2J2
SLRLSRQAEATARAQ

CNTROB

41

Q8N137
ARDRSRFARRITQAQ

PPP1R15A

586

O75807
SDFRQVRRSEASKRF

PTPN13

426

Q12923
ASALRRDVQVSDRVR

OPRL1

336

P41146
NRTRALVQALRRTTD

PNPLA8

361

Q9NP80
AQRQAQRLRERRAAS

VARS1

1211

P26640
LAARRQEQRATVRAL

SFI1

831

A8K8P3
RAREQSRSDFRNRDV

RBM6

206

P78332
AALAQRVRNRVNFRG

GTF2A2

46

P52657
ASAFRNVNTRRATQR

POLR1A

1361

O95602
DDNAVSRNAQRRRLS

RNF157

646

Q96PX1
AERERRVRELNSSNT

PLCB4

1101

Q15147
RFVQAEGRRATLQRL

TRADD

271

Q15628
NVRRVFQRARELASR

SPATA5L1

281

Q9BVQ7
RRRIRAQRGQSIAAS

NHS

461

Q6T4R5
FRRRKARDTFVLQAS

PLEKHG4

996

Q58EX7
VQLFNRRRQRVNEFT

SYNPO

171

Q8N3V7
RSVAEINRNLVQFSR

HAO2

336

Q9NYQ3
AAAARRQEQTLRDAT

EPPK1

3161

P58107
AAATAAARRQEQTLR

EPPK1

4226

P58107
RSFSSQRPVDRQNRR

PRRC2C

1541

Q9Y520
ANFTRRNLADCLRSR

PSMB2

81

P49721
NRDRDSIANRTRSRV

RNF6

411

Q9Y252
RNAAFFREVTRRTAR

SELENOO

306

Q9BVL4
QGAQRRVLRETSFQR

SHROOM1

146

Q2M3G4
RRSDRFATTLRNEIQ

SHROOM2

621

Q13796
EAQARVLRATSFKRR

SHROOM2

686

Q13796
GRSIQNRRKSERFAT

SHROOM4

576

Q9ULL8
NRRKSERFATNLRNE

SHROOM4

581

Q9ULL8
RARAKRNSRQFVAAL

TANC1

1376

Q9C0D5
RARAKRSSRQFAAAL

TANC2

1331

Q9HCD6
RFTNQTQGRDRLFRA

PEX11A

6

O75192
ARAIQGAFRQLRARR

IQANK1

66

A8MXQ7
DRAGNVVFRRSARNF

OXCT2

216

Q9BYC2
RSLQDSQLVARFQRR

SGPP2

6

Q8IWX5
VQRRSRLQRRQSFAV

SSH3

26

Q8TE77
RLQRRQSFAVLRGAV

SSH3

31

Q8TE77
RQSVRAGRVRATLFL

ACOT4

136

Q8N9L9
TRDGFRNRQQRVTKS

EIF4ENIF1

656

Q9NRA8
QRRARTTAVLVFDER

ADGRD2

111

Q7Z7M1
SREREAAAFRESLNR

CTSO

36

P43234
CQRFRTSRTERQQRD

NCAPD2

1211

Q15021
QRRRSRVFDLQFSTD

NCAPH

66

Q15003
SFLDQESRRRRFTIA

CNK3/IPCEF1

386

G9CGD6
SFLDQESRRRRFTIA

CNKSR3

386

Q6P9H4
DSQQRVRRNLRASAR

SLC7A6OS

81

Q96CW6
RALRQRQLDRAAAAV

SELENOS

56

Q9BQE4
AAANAARERSRVQTL

TCF24

51

Q7RTU0
VRQRQAANARERDRT

TCF15

71

Q12870
RRQAARELSIQRRSA

TIMELESS

321

Q9UNS1
QRRSALNVRLFLRDF

TIMELESS

331

Q9UNS1
RRRFASRIIDSLFNT

UGDH

311

O60701
ATDRQFSGARNQLRR

YBX3

211

P16989
QNTRARERKGQFRST

ZFHX2

1906

Q9C0A1
NLRRRSRSFTCNEFQ

RGS18

211

Q9NS28
AARQERAQSLRLRTI

RNF19A

266

Q9NV58
AERESNRAARAFLRA

SLC27A3

96

Q5K4L6
IDSFQRVDLRTRAFN

STOML1

111

Q9UBI4
VRAIASRARQAQERQ

PLCH2

1346

O75038
FLAAARELSLRRRQD

TMEM114

206

B3SHH9
RSVRSGRIRQNRQDL

RFPL2

206

O75678
ASRQQRFNTSIRDFE

SPTA1

1606

P02549
RFQQISSVRDRRRAV

SYNGR3

91

O43761
LTQTFRAREQLAAVR

UBXN1

226

Q04323
SRRLQRRLTEEFQNV

MRM2

201

Q9UI43
FQNRRALQDFRSRQE

PHLDA2

101

Q53GA4
ARALRQEFAASRAAA

PAM16

21

Q9Y3D7
AAGRRVSFQLQSRRR

VWA5B2

66

Q8N398
AIDNGRAAEFIRRRN

ZCRB1

86

Q8TBF4
QIASVRRSLFNNAER

XPO7

286

Q9UIA9
DRFTQNLSAFRREVN

XPO7

1056

Q9UIA9
RARAAREQATTNARI

UCN2

91

Q96RP3
SFSFRVNSLQERVDR

WASF1

61

Q92558
NAARERSRVRTLRQA

TCF23

81

Q7RTU1
RLRLQEAANRRFCSQ

VPS9D1

211

Q9Y2B5
RNRRNDTLDSTRTLY

TRPM8

11

Q7Z2W7
LLTARATNSQLFRRA

TG

2396

P01266
RERQRTQSLNEAFAA

TWIST1

116

Q15672
TEVRVANELNARRRS

SLC66A2

96

Q8N2U9
LRALTDSFRRRDTAQ

SRI

166

P30626
QRAQFAEATQRLSER

UFL1

16

O94874
SRARARDRNNVLNRA

PLPP7

6

Q8NBV4
IRALFQNTERRAAAL

ZW10

761

O43264
RRNRLSFNSEGVRAN

ZFHX3

566

Q15911
SARIRLTSQGQASRR

TTLL13

726

A6NNM8
RRVSAALAQQQVRRT

UTF1

96

Q5T230
FARNRQKSVRSLRDS

UNC79

1216

Q9P2D8
RQRTQSLNEAFAALR

TWIST2

76

Q8WVJ9
NFTSEAAFIENLRRR

MYO1C

56

O00159
AAFIENLRRRFRENL

MYO1C

61

O00159
FVTRSLNIAQAADRR

MYO7B

381

Q6PIF6
EAERTFSRSRAERQA

PPP1R12B

656

O60237