Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium:potassium:chloride symporter activity

SLC12A1 SLC12A2

8.35e-0531062GO:0008511
GeneOntologyMolecularFunctionpotassium:sodium symporter activity

SLC12A1 SLC12A2

8.35e-0531062GO:0009674
GeneOntologyCellularComponentmRNA editing complex

A1CF RBM47 SYNCRIP

4.37e-0671063GO:0045293
GeneOntologyCellularComponentapolipoprotein B mRNA editing enzyme complex

A1CF RBM47

2.52e-0451062GO:0030895
Domain-

KLHL2 KLHL3 KLHL13 HCFC2 KLHL18 KLHL17 KLHL4 KLHL26

1.32e-122710382.130.10.80
DomainGal_Oxidase_b-propeller

KLHL2 KLHL3 KLHL13 HCFC2 KLHL18 KLHL17 KLHL4 KLHL26

1.05e-11341038IPR015916
DomainGal_Oxase/kelch_b-propeller

KLHL2 KLHL3 MEGF8 KLHL13 HCFC2 KLHL18 KLHL17 KLHL4 KLHL26

3.30e-11591039IPR011043
DomainKelch_1

KLHL2 KLHL3 MEGF8 KLHL13 HCFC2 KLHL18 KLHL17 KLHL4 KLHL26

1.63e-10701039PF01344
DomainKelch_1

KLHL2 KLHL3 MEGF8 KLHL13 HCFC2 KLHL18 KLHL17 KLHL4 KLHL26

1.63e-10701039IPR006652
DomainKelch

KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

3.01e-08581037SM00612
DomainBACK

KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

3.84e-08601037SM00875
DomainBACK

KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

4.31e-08611037PF07707
DomainBACK

KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

4.31e-08611037IPR011705
DomainBTB-kelch_protein

KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL26

1.25e-07431036IPR017096
DomainHnRNP_R/Q_splicing_fac

A1CF RBM47 SYNCRIP

1.62e-0651033IPR006535
DomainBTB

KCTD12 KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

6.95e-061801038SM00225
DomainBTB

KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

8.05e-061311037PF00651
DomainBTB/POZ_dom

KCTD12 KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

8.49e-061851038IPR000210
DomainSKP1/BTB/POZ

KCTD12 KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

9.93e-061891038IPR011333
DomainBTB

KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

2.95e-051601037PS50097
DomainCOR

LRRK2 LRRK1

3.01e-0521032PF16095
DomainCOR

LRRK2 LRRK1

3.01e-0521032IPR032171
DomainNa/K/Cl_cotranspt

SLC12A1 SLC12A2

3.01e-0521032IPR002443
DomainEamA_dom

SLC35G6 SLC35G4 SLC35G3

5.67e-05141033IPR000620
DomainEamA

SLC35G6 SLC35G4 SLC35G3

5.67e-05141033PF00892
DomainAA_permease_N

SLC12A1 SLC12A2

9.00e-0531032IPR013612
DomainAA_permease_N

SLC12A1 SLC12A2

9.00e-0531032PF08403
DomainNucleotide-bd_a/b_plait

A1CF RBMXL3 SRSF7 CIRBP SRRT RBM47 RBFOX2 SYNCRIP

9.13e-052581038IPR012677
DomainRRM_1

A1CF RBMXL3 SRSF7 CIRBP RBM47 RBFOX2 SYNCRIP

1.54e-042081037PF00076
DomainROC_dom

LRRK2 LRRK1

1.79e-0441032IPR020859
DomainROC

LRRK2 LRRK1

1.79e-0441032PS51424
DomainRRM

A1CF RBMXL3 SRSF7 CIRBP RBM47 RBFOX2 SYNCRIP

2.00e-042171037SM00360
DomainRRM_dom

A1CF RBMXL3 SRSF7 CIRBP RBM47 RBFOX2 SYNCRIP

2.63e-042271037IPR000504
DomainRRM

A1CF RBMXL3 SRSF7 CIRBP RBM47 RBFOX2 SYNCRIP

2.85e-042301037PS50102
DomainCadherin_cytoplasmic-dom

DSC2 CDH8 CDH11

3.43e-04251033IPR000233
DomainCadherin_C

DSC2 CDH8 CDH11

3.43e-04251033PF01049
Domain-

A1CF RBMXL3 SRSF7 CIRBP RBM47 RBFOX2 SYNCRIP

4.07e-0424410373.30.70.330
DomainCatenin_binding_dom

DSC2 CDH8 CDH11

5.36e-04291033IPR027397
Domain-

DSC2 CDH8 CDH11

5.36e-042910334.10.900.10
DomainSLC12A_fam

SLC12A1 SLC12A2

6.21e-0471032IPR004842
DomainSLC12_C

SLC12A1 SLC12A2

8.25e-0481032IPR018491
DomainSLC12

SLC12A1 SLC12A2

8.25e-0481032PF03522
DomainConA-like_dom

LAMA1 THBS3 NRXN3 HNRNPUL2 MID1 SEL1L3

1.35e-032191036IPR013320
Domainfn3

PTPRH MID1 FLRT1 HCFC2 MYBPC2

2.04e-031621035PF00041
DomainRoc

LRRK2 LRRK1

2.26e-03131032PF08477
DomainMIRO-like

LRRK2 LRRK1

2.26e-03131032IPR013684
Domain-

GTPBP6 NOA1 LRRK2 PFKFB1 LRRK1 OPA1 HNRNPUL2 RECQL5 HLTF DDX53 COASY

2.71e-03746103113.40.50.300
DomainFN3

PTPRH MID1 FLRT1 HCFC2 MYBPC2

3.62e-031851035SM00060
DomainMMR_HSR1

GTPBP6 NOA1

3.88e-03171032PF01926
DomainLaminin_G

LAMA1 THBS3 NRXN3

4.03e-03581033IPR001791
DomainGTP_binding_domain

GTPBP6 NOA1

4.84e-03191032IPR006073
DomainFibrinogen_CS

ANGPT4 FIBCD1

4.84e-03191032IPR020837
DomainPyr_redox_2

GSR PCYOX1

4.84e-03191032PF07992
DomainFN3

PTPRH MID1 FLRT1 HCFC2 MYBPC2

4.92e-031991035PS50853
Pubmed

Update on the Kelch-like (KLHL) gene family.

KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

4.41e-1141107723676014
Pubmed

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.

ZNF326 A1CF SRSF7 LARP1 CIRBP SRRT FAM120A HNRNPUL2 RBM47 SYNCRIP

7.93e-092581071037794589
Pubmed

RT-PCR of fatty acid elongases.

SLC35G6 SLC35G4 SLC35G3

1.13e-07410739056918
Pubmed

Emergence of primate genes by retrotransposon-mediated sequence transduction.

SLC35G6 SLC35G4 SLC35G3

1.13e-074107317101974
Pubmed

A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.

KLHL2 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

3.04e-0787107637495603
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

KCTD12 ZNF326 SRSF7 DNAJA2 LARP1 ACTL6A DPM1 OPA1 STT3B GSR SRRT MAPK15 FAM120A HNRNPUL2 COASY BSN PCYOX1 SYNCRIP

3.47e-0714251071830948266
Pubmed

The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.

ZNF326 LARP1 CIRBP SRRT FAM120A HNRNPUL2 SYNCRIP

3.82e-07147107728977470
Pubmed

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.

ZNF326 SRSF7 LARP1 DPP3 OPA1 SRRT HLTF

3.31e-06203107735012549
Pubmed

Proteome-wide characterization of N-glycosylation events by diagonal chromatography.

PSG2 PSG11 PGLYRP2 PZP PCYOX1

4.16e-0677107516944957
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

NOA1 TMEM14C LARP1 DPM1 SRRT FAM120A HNRNPUL2 MID1 HLTF PZP RBM47

5.46e-066501071138777146
Pubmed

Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.

ZNF326 DNAJA2 LARP1 ACTL6A ANTXR2 FAM120A HNRNPUL2 SYNCRIP

7.12e-06321107832098917
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

ZNF326 SRSF7 NOA1 DNAJA2 LARP1 DPM1 FAM120A HNRNPUL2 PLOD1 RBFOX2 SYNCRIP

8.12e-066781071130209976
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

KCTD12 ZNF326 SRSF7 DNAJA2 PSMB7 LARP1 ACTL6A DPM1 PGM3 STT3B FAM120A HNRNPUL2 HLTF HCFC2 PLOD1 SYNCRIP

8.52e-0614401071630833792
Pubmed

Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson's disease.

LRRK2 LRRK1

9.38e-062107218272292
Pubmed

Motor Impairments and Dopaminergic Defects Caused by Loss of Leucine-Rich Repeat Kinase Function in Mice.

LRRK2 LRRK1

9.38e-062107235534227
Pubmed

Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1.

LRRK2 LRRK1

9.38e-062107217394548
Pubmed

Molecular cloning and chromosome localization of a putative basolateral Na(+)-K(+)-2Cl- cotransporter from mouse inner medullary collecting duct (mIMCD-3) cells.

SLC12A1 SLC12A2

9.38e-06210727929272
Pubmed

Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2.

SLC12A1 SLC12A2

9.38e-06210728640224
Pubmed

The Na-K-Cl cotransporters.

SLC12A1 SLC12A2

9.38e-06210729672238
Pubmed

Human leucine-rich repeat kinase 1 and 2: intersecting or unrelated functions?

LRRK2 LRRK1

9.38e-062107222988872
Pubmed

Expression of the basolateral Na-K-Cl cotransporter during mouse nephrogenesis and embryonic development.

SLC12A1 SLC12A2

9.38e-062107216814616
Pubmed

Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms.

LRRK2 LRRK1

9.38e-062107233459343
Pubmed

Genetic Analysis of LRRK1 and LRRK2 Variants in Essential Tremor Patients.

LRRK2 LRRK1

9.38e-062107229812962
Pubmed

Dynamic and redundant regulation of LRRK2 and LRRK1 expression.

LRRK2 LRRK1

9.38e-062107218045479
Pubmed

Heterodimerization of Lrrk1-Lrrk2: Implications for LRRK2-associated Parkinson disease.

LRRK2 LRRK1

9.38e-062107220144646
Pubmed

Leucine-rich repeat kinase 1: a paralog of LRRK2 and a candidate gene for Parkinson's disease.

LRRK2 LRRK1

9.38e-062107217225181
Pubmed

Variants in the LRRK1 gene and susceptibility to Parkinson's disease in Norway.

LRRK2 LRRK1

9.38e-062107217324517
Pubmed

Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice.

LRRK2 LRRK1

9.38e-062107229056298
Pubmed

Increased Slc12a1 expression in β-cells and improved glucose disposal in Slc12a2 heterozygous mice.

SLC12A1 SLC12A2

9.38e-062107226400961
Pubmed

Expression of leucine-rich-repeat-kinase 2 (LRRK2) during embryonic development.

LRRK2 LRRK1

9.38e-062107220403420
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

KCTD12 ZNF326 PSMB7 OPA1 PGM3 STT3B GSR FAM120A PTPRH HNRNPUL2 ATP2A1 PLOD1 SYNCRIP

9.61e-069741071328675297
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

ZNF326 SRSF7 LARP1 SRRT FAM120A HNRNPUL2 SYNCRIP

1.10e-05244107729884807
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

ZNF326 SRSF7 NOA1 DNAJA2 LARP1 CIRBP SRRT FAM120A HNRNPUL2 PLOD1 SYNCRIP

1.30e-057131071129802200
Pubmed

Genomic analysis of mouse retinal development.

SOX11 PCNX3 SLC25A33 AAK1 STK35 GSR CIRBP FAM120A HNRNPUL2 SLC25A44 BSN KLHL18 CDH11

1.35e-0510061071315226823
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

ZNF326 MYCBP2 SLC25A33 LARP1 ADCY1 FAM120A PLOD1 RBFOX2 SYNCRIP

1.35e-05462107931138677
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

DSC2 DNAJA2 UBXN6 LRRK2 ADCY1 GSR FAH SLC12A1 MEGF8 LRP2 COASY PLOD1 PCYOX1

1.50e-0510161071319056867
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

DNAJA2 LARP1 DPM1 OPA1 PGM3 CIRBP SRRT HNRNPUL2 PLOD1 RBFOX2 SYNCRIP

1.51e-057251071127025967
Pubmed

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

A1CF SRSF7 PSMB7 LARP1 FAM120A HNRNPUL2 RBM47 PLOD1 SYNCRIP

1.52e-05469107937314180
Pubmed

Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis.

ZNF326 SRSF7 SRRT FAM120A HNRNPUL2 SYNCRIP

1.60e-05172107626336360
Pubmed

Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver.

A1CF RBM47

2.81e-053107230309881
Pubmed

Two-hybrid cloning identifies an RNA-binding protein, GRY-RBP, as a component of apobec-1 editosome.

A1CF SYNCRIP

2.81e-053107211352648
Pubmed

Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family.

SLC12A1 SLC12A2

2.81e-05310728663127
Pubmed

Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers.

LRRK2 LRRK1

2.81e-053107222952686
Pubmed

Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment.

LRRK2 LRRK1

2.81e-053107219712061
Pubmed

Developmental expression of PAM (protein associated with MYC) in the rodent brain.

MYCBP2 ADCY1

2.81e-053107212036515
Pubmed

Comparison of RNA Editing Activity of APOBEC1-A1CF and APOBEC1-RBM47 Complexes Reconstituted in HEK293T Cells.

A1CF RBM47

2.81e-053107230844405
Pubmed

Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.

ZNF326 LARP1 ACTL6A CIRBP FAM120A ATP2A1 SYNCRIP

2.86e-05283107728533407
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ZNF326 SRSF7 MYCBP2 HECTD4 ACTL6A OPA1 STT3B CIRBP SRRT HNRNPUL2 PZP PLOD1 SYNCRIP

2.89e-0510821071338697112
Pubmed

Novel CUL3 Variant Causing Familial Hyperkalemic Hypertension Impairs Regulation and Function of Ubiquitin Ligase Activity.

KLHL3 KLHL13 KLHL18 KLHL26

2.95e-0557107434878901
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

SRSF7 MYCBP2 DNAJA2 PSMB7 LARP1 ACTL6A DPM1 OPA1 PGM3 KLHL13 HLTF PLOD1 RBFOX2 SYNCRIP

3.20e-0512571071437317656
Pubmed

Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system.

SRSF7 NRXN3 RBFOX2 SYNCRIP

3.62e-0560107429055695
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

KCTD12 ZNF326 SRSF7 LARP1 CIRBP SRRT FAM120A HNRNPUL2 RBM47 RBFOX2 SYNCRIP

4.03e-058071071122681889
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

LAMA1 LRRK2 ANGPT4 MID1 LRP2 BSN

4.66e-05208107633230847
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

KCTD12 GTPBP6 NOA1 DNAJA2 PSMB7 AAK1 DPM1 STT3B RBFOX2

5.05e-05547107937267103
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

ZNF326 DNAJA2 LARP1 ACTL6A SRRT FAM120A HNRNPUL2 RBFOX2 SYNCRIP

5.34e-05551107934728620
Pubmed

Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing.

A1CF SYNCRIP

5.60e-054107211134005
Pubmed

Impaired phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndrome.

SLC12A1 SLC12A2

5.60e-054107221972418
Pubmed

Targeted disruption of leucine-rich repeat kinase 1 but not leucine-rich repeat kinase 2 in mice causes severe osteopetrosis.

LRRK2 LRRK1

5.60e-054107223526378
Pubmed

Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes.

LAMA1 PLOD1

5.60e-054107216467571
Pubmed

Interactions with WNK (with no lysine) family members regulate oxidative stress response 1 and ion co-transporter activity.

SLC12A1 SLC12A2

5.60e-054107222989884
Pubmed

Altered expression of regulators of the cortical chloride transporters NKCC1 and KCC2 in schizophrenia.

SLC12A1 SLC12A2

5.60e-054107220819979
Pubmed

Immunoprecipitation and mass spectrometry defines an extensive RBM45 protein-protein interaction network.

LARP1 SRRT FAM120A HNRNPUL2 SYNCRIP

6.56e-05136107526979993
Pubmed

Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.

SRSF7 LARP1 SRRT FAM120A HNRNPUL2 SYNCRIP

6.85e-05223107620020773
Pubmed

Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.

KLHL2 MID1 KLHL18 KLHL4 KLHL26

7.03e-05138107528786561
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

ZNF326 DNAJA2 LARP1 ACTL6A DPM1 SRRT HLTF SMAD3 SYNCRIP

8.21e-05583107929844126
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

KCTD12 DPY19L1 MYCBP2 LAMA1 STT3B GSR THBS3 SLC12A2 MEGF8 HNRNPUL2 SEL1L3 PLOD1 PCYOX1

8.35e-0512011071335696571
Pubmed

Structural and biochemical characterization of the KLHL3-WNK kinase interaction important in blood pressure regulation.

KLHL2 KLHL3

9.32e-055107224641320
Pubmed

Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin.

CDH8 CDH11

9.32e-05510727982033
Pubmed

A strategy for the generation, characterization and distribution of animal models by The Michael J. Fox Foundation for Parkinson's Research.

LRRK2 LRRK1

9.32e-055107224046356
Pubmed

The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay.

A1CF SYNCRIP

9.32e-055107212881431
Pubmed

cea5, a structurally divergent member of the murine carcinoembryonic antigen gene family, is exclusively expressed during early placental development in trophoblast giant cells.

PSG2 PSG11

9.32e-05510729395467
Pubmed

Trophoblast cell-specific carcinoembryonic antigen cell adhesion molecule 9 is not required for placental development or a positive outcome of allotypic pregnancies.

PSG2 PSG11

9.32e-055107210982830
Pubmed

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.

A1CF DNAJA2 AAK1 LARP1 CIRBP FAM120A HNRNPUL2 RBM47

9.72e-05464107832457219
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

A1CF RBMXL3 SRSF7 CIRBP KLHL3 RBM47 SYNCRIP

1.03e-04347107716033648
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

ZNF326 MYCBP2 DNAJA2 LARP1 ACTL6A DPM1 SRRT FAM120A HNRNPUL2 SYNCRIP

1.21e-047591071035915203
Pubmed

Human transcription factor protein interaction networks.

ZNF326 DNAJA2 PSMB7 LARP1 ACTL6A DPM1 CIRBP SRRT FAM120A HNRNPUL2 RECQL5 LRP2 HCFC2 SYNCRIP

1.26e-0414291071435140242
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

ZNF326 LAMA1 PSMB7 LARP1 NRXN3 FAM120A

1.31e-04251107628077445
Pubmed

Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism.

CDH8 CDH11

1.40e-046107234135003
Pubmed

Coordinate expression of splice variants of the murine pregnancy-specific glycoprotein (PSG) gene family during placental development.

PSG2 PSG11

1.40e-04610728973644
Pubmed

Expression analysis of Lrrk1, Lrrk2 and Lrrk2 splice variants in mice.

LRRK2 LRRK1

1.40e-046107223675505
Pubmed

Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.

ZNF326 NRXN3

1.40e-046107220197096
Pubmed

GRAMD4 inhibits tumour metastasis by recruiting the E3 ligase ITCH to target TAK1 for degradation in hepatocellular carcinoma.

SRSF7 NOA1 SYNCRIP

1.44e-0433107334841685
Pubmed

Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.

SRSF7 LARP1 FAM120A HNRNPUL2 RBFOX2 SYNCRIP

1.58e-04260107636199071
Pubmed

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.

ACTL6A SLC12A1 LRP2

1.72e-0435107332504627
Pubmed

Characterization of cadherins expressed by murine thymocytes.

CDH8 CDH11

1.95e-04710728620560
Pubmed

C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47.

A1CF RBM47

1.95e-047107224916387
Pubmed

Graded and areal expression patterns of regulatory genes and cadherins in embryonic neocortex independent of thalamocortical input.

CDH8 CDH11

1.95e-047107210594069
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

SRSF7 DNAJA2 LARP1 OPA1 FAM120A HNRNPUL2 HLTF PLOD1 SYNCRIP

1.96e-04655107935819319
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

SRSF7 GTPBP6 MYCBP2 NOA1 DNAJA2 PSMB7 OPA1 STT3B FAM120A SLC12A2 HNRNPUL2 LRP2 PLOD1 SYNCRIP

2.02e-0414961071432877691
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

DSC2 LARP1 SRRT FAM120A HNRNPUL2 SYNCRIP

2.10e-04274107634244482
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

KCTD12 MYCBP2 DNAJA2 PSMB7 LARP1 ACTL6A GSR CIRBP FAM120A MID1 HCFC2 SYNCRIP

2.21e-0411491071235446349
Pubmed

Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity.

UBXN6 PSMB7 UBA7 KLHL26

2.26e-0496107434599178
Pubmed

WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ΔNp73 levels.

DNAJA2 DPM1 RECQL5 SYNCRIP

2.35e-0497107425071155
Pubmed

Affinity purification strategies for proteomic analysis of transcription factor complexes.

ZNF326 SRSF7 ACTL6A HNRNPUL2

2.35e-0497107423937658
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

ZNF326 SRSF7 NOA1 DNAJA2 PSMB7 LARP1 ACTL6A DPM1 OPA1 CIRBP FAM120A PLOD1 SYNCRIP

2.36e-0413351071329229926
Pubmed

KLHL2 interacts with and ubiquitinates WNK kinases.

KLHL2 KLHL3

2.59e-048107223838290
Pubmed

Cell-type specific regulator RBPMS switches alternative splicing via higher-order oligomerization and heterotypic interactions with other splicing regulators.

RBM47 RBFOX2

2.59e-048107237548402
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 10 expressed specifically early in pregnancy in the decidua is dispensable for normal murine development.

PSG2 PSG11

2.59e-048107212482980
Pubmed

The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed.

PSG2 PSG11

2.59e-04810721690992
Pubmed

Similar effects of all WNK3 variants on SLC12 cotransporters.

SLC12A1 SLC12A2

2.59e-048107221613606
InteractionELAVL2 interactions

ZNF326 AAK1 LARP1 SRRT FAM120A HNRNPUL2 RBM47 RBFOX2 SYNCRIP

5.66e-071881049int:ELAVL2
InteractionKLHL3 interactions

KLHL2 KLHL3 SYNCRIP KLHL17 KLHL26

2.74e-06431045int:KLHL3
InteractionDUSP11 interactions

KCTD12 SRSF7 FAM120A HNRNPUL2 PLOD1 SYNCRIP

4.16e-06821046int:DUSP11
InteractionNUDCD3 interactions

KLHL2 KLHL3 KLHL13 LTK HCFC2 KLHL18 KLHL26

1.22e-051491047int:NUDCD3
InteractionKLHL17 interactions

KLHL2 KLHL3 KLHL18 KLHL17

2.75e-05341044int:KLHL17
InteractionENKUR interactions

LRRK2 LRRK1 OPA1

2.84e-05121043int:ENKUR
InteractionIGFBP4 interactions

MYCBP2 MEGF8 KLHL13 KLHL26

5.85e-05411044int:IGFBP4
InteractionFAM120A interactions

ZNF326 SRSF7 NOA1 LARP1 FAM120A HNRNPUL2 RBM47 RBFOX2 SYNCRIP

8.19e-053491049int:FAM120A
InteractionBLVRA interactions

DNAJA2 PGM3 THBS3 LTK PCYOX1

8.30e-05861045int:BLVRA
InteractionLARP1B interactions

SRSF7 LARP1 FAM120A HNRNPUL2 RBM47 SYNCRIP

8.42e-051391046int:LARP1B
GeneFamilyKelch like|BTB domain containing

KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

2.32e-1042707617
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL2 KLHL3 KLHL13 KLHL18 KLHL17 KLHL4 KLHL26

8.53e-07134707861
GeneFamilyRNA binding motif containing

A1CF RBMXL3 SRSF7 CIRBP RBM47 RBFOX2 SYNCRIP

1.82e-05213707725
GeneFamilyCD molecules|V-set domain containing|Pregnancy specific glycoproteins

PSG2 PSG11

7.95e-04117021315
GeneFamilySolute carriers

SLC25A33 SLC35G6 SLC35G4 SLC12A1 SLC12A2 SLC35G3 SLC25A44

8.27e-04395707752
GeneFamilyCD molecules|Type II classical cadherins

CDH8 CDH11

1.12e-03137021186
GeneFamilyFibronectin type III domain containing

PTPRH MID1 FLRT1 MYBPC2

3.44e-03160704555
GeneFamilyFibrinogen C domain containing

ANGPT4 FIBCD1

4.18e-0325702554
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

RAPH1 PCNX3 LARP1 FAM120A PTPRH RBM47

2.39e-061591076655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DSC2 LRRK2 MAPK15 SEL1L3 LRP2 LYG1

7.49e-0619410768ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

KCTD12 DSC2 RAPH1 LRRK2 LRRK1 SIDT2

8.17e-06197107615b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

KCTD12 DSC2 RAPH1 LRRK2 LRRK1 SIDT2

8.17e-061971076a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellTracheal-10x3prime_v2-Stromal-Schwann-Schwann_nonmyelinating|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NDRG2 MCOLN1 ADCY1 KLHL3 NRXN3 KLHL26

8.66e-061991076a92718a3f1153b8d2196fd343ed5bc0ebc98cad7
ToppCellTracheal-10x3prime_v2-Stromal-Schwann|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NDRG2 MCOLN1 ADCY1 KLHL3 NRXN3 KLHL26

8.66e-0619910768dc65662c3ca1db2ba0091332f0658abc0afc5de
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Interneuron|10w / Sample Type, Dataset, Time_group, and Cell type.

SOX11 RAPH1 ADCY1 NRXN3 CDH11 RBFOX2

8.91e-062001076f5c63ef52bd7a898cf009b8bf9b2f7f4890d1c9b
ToppCellPosterior_cortex-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FSIP2 SLC35G3 BPIFB4 MOS

2.32e-056910744831573a45ace5f06cd409f0e75bce838ed65a88
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FFAR1 ADCY1 HLTF HCFC2 RSPH10B

2.74e-051461075c0e1836845c083bf9d88a620da27acbfdea9fb20
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA1 NDRG2 SLC12A1 RBM47 RSPH10B

3.42e-0515310750307f10e772021ae68a42690634df458672a6df9
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STK35 FLRT1 PZP ATP2A1 CDH11

3.87e-0515710751f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOX3 FAH LRP2 COASY PZP

5.05e-0516610758ab18c9d911eb3a9970bba7a769294b0927538f7
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOX3 FAH LRP2 COASY PZP

5.81e-05171107548fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCelldroplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOX3 FAH LRP2 COASY PZP

5.81e-05171107505fcc72df50a380a913821b5781d9621df37d328
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCTD12 FFAR1 ADCY1 BSN RSPH10B

6.14e-05173107507798461d12d04f3dabff03481c999cb07c5af2f
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DSC2 TMEM14C DESI2 THBS3 KLHL13

6.31e-051741075e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV2 MAPK15 CFAP77 SLC35G3 LTK

6.66e-051761075ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

DSC2 HECTD4 TMEM14C THBS3 KLHL13

6.66e-051761075bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WHRN DPY19L1 LRRK1 MID1 CDH8

7.22e-051791075c815eb9f760fe4ca7a5e49beb224659f0b864f22
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC12A2 ANGPT4 LRP2 LTK RBM47

7.22e-051791075bf012825e88626e59cd1deebf67c2cd269ce4829
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A1CF LRRK2 SEL1L3 LRP2 SMAD3

7.22e-05179107558ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WHRN DPY19L1 LRRK1 MID1 CDH8

7.22e-05179107553e700494d251ec5649b2dea5fc7d5aeeeed572b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WHRN DPY19L1 LRRK1 MID1 CDH8

7.41e-0518010758923a42a6db9c6e9f3ce2ca9530e620dfea700ba
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRRK2 SEL1L3 ADAMTS15 LRP2 SMAD3

7.61e-0518110756956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCTD12 SOX11 ANTXR2 SLC12A2 CDH8

8.01e-051831075262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCTD12 SOX11 ANTXR2 SLC12A2 CDH8

8.01e-051831075c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

LRRK2 SEL1L3 LRP2 FGGY LYG1

8.22e-05184107551ed1ebfdef45149541917c66cbacad87072e51f
ToppCell(2)_Fibroblasts-(20)_Fibro-1|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

KCTD12 ANTXR2 KLHL13 ADAMTS15 CDH11

8.65e-051861075e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MYCBP2 AAK1 NRXN3 BSN CDH8

8.65e-0518610753f889083fcffe516388e9b03a5e23af2010ced33
ToppCell18-Airway-Epithelial-Submucosal_gland|Airway / Age, Tissue, Lineage and Cell class

DSC2 NDRG2 SLC12A2 RBM47 FGGY

9.32e-051891075c1ea2dc44cf5340378e56e0ffc2e6f64e6c95a58
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA1 NRXN3 SEL1L3 LRP2 RBM47

9.56e-051901075625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA1 NRXN3 SEL1L3 LRP2 RBM47

1.00e-04192107525378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYCBP2 AAK1 NRXN3 BSN CDH8

1.00e-0419210754c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA1 NRXN3 SEL1L3 LRP2 RBM47

1.00e-041921075d3634574b2e8d2ded6446969361b70761b331aea
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA1 NRXN3 SEL1L3 LRP2 RBM47

1.00e-041921075b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL2 RAPH1 MID1 RBM47 SMAD3

1.00e-0419210752510f22197502f60fd266b7f42eff040f25b8ae7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL2 RAPH1 MID1 RBM47 SMAD3

1.00e-041921075e8e316f396834bcd34843e56e1d86f310fd6aada
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA1 NRXN3 SEL1L3 LRP2 RBM47

1.00e-0419210751aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCelldroplet-Mammary_Gland-nan-18m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIRBP NRXN3 SLC12A2 MID1 RBM47

1.08e-041951075c771ac1db8bd5f3a80bd3484094a58c28983f97b
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCTD12 DSC2 MCOLN1 FAH RBM47

1.19e-041991075b827dd8a249f904a0ff930a6c4d3b00fb7bc6fb1
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MYCBP2 LAMA1 ADAMTS15 PZP CDH11

1.19e-041991075a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCTD12 DSC2 MCOLN1 FAH RBM47

1.19e-041991075c0dcdda30485bb920d3706dcfb06f11b76b6ea37
ToppCellParenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DSC2 LRRK1 ANTXR2 SLC12A1 MYBPC2

1.19e-041991075f4ab29f99ce45a3044d2e9f356dc24d3c5e7121f
ToppCellNeuronal-Excitatory-eG(DAPK2)-|Neuronal / cells hierarchy compared to all cells using T-Statistic

WHRN DPY19L1 LRRK1 MID1 CDH8

1.22e-0420010757cea58e2691564e653cc972bf5aaff2df1f2666e
ToppCellNeuronal-Excitatory-eG(DAPK2)--|Neuronal / cells hierarchy compared to all cells using T-Statistic

WHRN DPY19L1 LRRK1 MID1 CDH8

1.22e-042001075193c42c31a366a60d80c4c1fc6a1592a5b01a3ad
ToppCellNeuronal-Excitatory-eG(DAPK2)---|Neuronal / cells hierarchy compared to all cells using T-Statistic

WHRN DPY19L1 LRRK1 MID1 CDH8

1.22e-0420010757c780e995a5fc3793080da61b6bf7a12880e9df8
ToppCellNeuronal-Excitatory-eG(DAPK2)----L4-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

WHRN DPY19L1 LRRK1 MID1 CDH8

1.22e-042001075d0b31dc5eedc0635c0d7ceabaa6202386cf2a4a4
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

SOX11 MYCBP2 ADCY1 NRXN3 RBFOX2

1.22e-042001075bad32a95b759fad509401b07bc96a56687c2a592
ToppCellNeuronal-Excitatory-eG(DAPK2)|Neuronal / cells hierarchy compared to all cells using T-Statistic

WHRN DPY19L1 LRRK1 MID1 CDH8

1.22e-0420010758444ae3c10b1152dec67ca812e6c417cc3b9cf89
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MYCBP2 LAMA1 ADAMTS15 PZP CDH11

1.22e-042001075a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Interneuron|2m / Sample Type, Dataset, Time_group, and Cell type.

SOX11 NRXN3 KLHL13 CDH8 RBFOX2

1.22e-04200107508bee924a2654e05df3b39e8a51f93c8b3472175
DrugLisinopril [83915-83-7]; Down 200; 9uM; HL60; HT_HG-U133A

UBXN6 AAK1 LRRK1 NDRG2 SIDT2 HCFC2 FGGY RBFOX2 PCYOX1

3.32e-0719710592371_DN
DrugAdrenosterone [382-45-6]; Down 200; 13.4uM; MCF7; HT_HG-U133A

WHRN KCTD12 DSC2 THBS3 SIDT2 HNRNPUL2 HCFC2 CDH8

3.85e-0619810586486_DN
DrugTrolox [53188-07-1]; Up 200; 16uM; HL60; HG-U133A

OPA1 ACOX3 KLHL3 UBA7 RECQL5 SLC25A44 KLHL18 FGGY

4.00e-0619910581734_UP
Diseaseurate measurement

A1CF PCNX3 HECTD4 AAK1 STT3B THBS3 SLC12A1 LRP2 FLRT1 RBM47

1.08e-0389510210EFO_0004531
Diseaseresponse to platinum based chemotherapy

ADCY1 NRXN3

1.75e-03181022EFO_0004647
Diseasecongenital heart disease (implicated_via_orthology)

LRP2 HCFC2 MYBPC2

1.78e-03691023DOID:1682 (implicated_via_orthology)
Diseasefactor VIII measurement, Ischemic stroke

HECTD4 CFAP77

1.95e-03191022EFO_0004630, HP_0002140
DiseaseLeft Ventricle Remodeling

OPA1 SMAD3

2.38e-03211022C0600520
DiseaseVentricular Remodeling

OPA1 SMAD3

2.38e-03211022C0600519

Protein segments in the cluster

PeptideGeneStartEntry
GGDSGLSVRGKQYAY

PFKFB1

271

P16118
TGGRYGKATIEGYYQ

PGM3

171

O95394
GINFNYGLYIRGLDG

CFAP77

116

Q6ZQR2
LLYRGGYFSGEQAGE

ACOX3

606

O15254
KDSYVRYTRGTGGRG

A1CF

306

Q9NQ94
AGVRGLGGRGYLAYT

A1CF

391

Q9NQ94
GSGYIGRVFGIGRQQ

AAK1

31

Q2M2I8
AENAYGGHRGLGRYR

BPIFB4

126

P59827
AVASYDYLVIGGGSG

GSR

61

P00390
FDIGSYTVRAGYAGE

ACTL6A

16

O96019
VDASYYGGRGVGGIK

ANTXR2

376

P58335
SGIEVYGREFAYGGH

DESI2

31

Q9BSY9
TYNYEGRGSVAGSVG

DSC2

856

Q02487
DIVSGTRYKGNGGVY

DPM1

141

O60762
RYMAIGGYVGAATVG

ATP2A1

836

O14983
GGLRGAFGYRGAEYV

ADAMTS15

121

Q8TE58
VGQGYYGAGLGVVER

PZP

696

P20742
SYLGGYSAGRGIYSR

RBM47

396

A0AV96
AGYGGSHISGYATLR

RAPH1

1216

Q70E73
YGVGAVASLYRGGYS

RBFOX2

371

O43251
FRYQGYIGAALVLGG

PSMB7

131

Q99436
DVSLGRYAYVRGGGD

MCOLN1

141

Q9GZU1
GEFVNGYRHGRGKFY

RSPH10B

286

P0C881
GEFVNGYRHGRGKFY

RSPH10B2

286

B2RC85
GRGGTRTHFDYQFGY

LARP1

351

Q6PKG0
GTGYRFRVAAINGCG

HCFC2

646

Q9Y5Z7
GEVRFRGLTGNYYPG

LEXM

151

Q3ZCV2
YRGVGSRYIMGSGES

GTPBP6

241

O43824
GGSGTVIYRARYQGQ

LRRK1

1251

Q38SD2
QGGARALLGGYSQAY

MAPK15

511

Q8TD08
GFADGRYLGQGLQYG

BSN

2026

Q9UPA5
EGGGIETYRYRPTYG

FSIP2

1701

Q5CZC0
YGYEDFQVGARGRGG

SYNCRIP

486

O60506
GGGATYVFRVRAGEL

LTK

211

P29376
VRRSYTFGLAGGGYE

PCNX3

671

Q9H6A9
GAGIGGTSAAYYLRQ

PCYOX1

41

Q9UHG3
SQYYGAGVARDPGFR

PGLYRP2

301

Q96PD5
RGQGYVGGQRRGYDN

HNRNPUL2

656

Q1KMD3
VGGQRRGYDNRAYGQ

HNRNPUL2

661

Q1KMD3
GRLFQGQLSGLYYDG

NRXN3

1226

Q9Y4C0
IYGTYLSGSRLGGLV

DPY19L1

176

Q2PZI1
VAAVGSRLYISGGFG

MEGF8

1846

Q7Z7M0
GDGSFGSVYRAAYEG

LRRK2

1886

Q5S007
TGDVAGGRALYEGYA

DPP3

631

Q9NY33
VYYTVRGEGSRFGAI

LRP2

4101

P98164
TPVIRTFGRGGRYYG

FAM120A

991

Q9NZB2
VAEYGGNTLGYGSRS

HECTD4

691

Q9Y4D8
RRGGVGVATYNGFLY

KLHL4

606

Q9C0H6
VGVDYEGGGCRFLRY

PLOD1

671

Q02809
RYLILGSAVGGGYTA

OPA1

101

O60313
YDRYGEQGLREGSGG

DNAJA2

66

O60884
GYTRTGGGAVSGRSY

ADCY1

771

Q08828
GYLYAVGGRNAAGEL

KLHL13

441

Q9P2N7
AVGNRLYAVGGYDGT

KLHL17

386

Q6TDP4
ASCGRLYAVGGYDGQ

KLHL18

521

O94889
AASGGRLYISGGYGI

KLHL26

456

Q53HC5
YAGGGFLAALSAGRY

FFAR1

91

O14842
YYVGVDVGTGSVRAA

FGGY

11

Q96C11
LRGRYGYVGSSSGHD

FSCN3

391

Q9NQT6
QIYGYEGRGSVAGSL

CDH11

741

P55287
YRLSVVGYSGSAGRQ

ANGPT4

406

Q9Y264
DQYLRGGLCAYSGGA

LYG1

151

Q8N1E2
GTAYARYGSFGVGLF

FIBCD1

341

Q8N539
GKLYAVGGYDGASRQ

KLHL3

441

Q9UH77
GFRRLGCGYGYGSRS

KRTAP6-1

41

Q3LI64
YVHRVGYIGRTGKTG

DDX53

551

Q86TM3
IITGYCQGDGYRIGF

FAH

391

P16930
GSLRGHVVGLRYYTG

HLTF

61

Q14527
IYGYEGRGSVAGSLS

CDH8

746

P55286
GYGTTRGYRDGGIPD

FLRT1

626

Q9NZU1
SGGRKYTYRFGGRVP

ETV2

311

O00321
KRGDGTRGVTGYFTF

PSG11

126

Q9UQ72
TIGYRGSYTIGRDAQ

KCTD12

211

Q96CX2
RYRGDVYLVGATNAG

NOA1

336

Q8NC60
LGAGGFGSVYKATYR

MOS

66

P00540
YGGAGDDYVLGSLRV

SOX11

191

P35716
GVYTALGYVEAFLGG

SLC35G3

186

Q8N808
TAGYFIIGGSRYVAG

SEL1L3

396

Q68CR1
AGTGDLSYGYQGRSF

SIDT2

376

Q8NBJ9
GDVYLYGGRGLLNVS

PRSS29P

131

A6NIE9
IGVGVGAGAYILARY

NDRG2

141

Q9UN36
GRLFQGQLSGLYYDG

NRXN3

221

Q9HDB5
GYYRVDGILFGGICQ

LAMA1

726

P25391
NGFVRGGGAYYLISR

SLC12A1

236

Q13621
KIGSGYSGTVRGHIY

MYCBP2

386

O75592
GLTIRGGAEYGLGIY

WHRN

291

Q9P202
GGAEYGLGIYITGVD

WHRN

296

Q9P202
ADGLRGFYRGYVASL

SLC25A44

176

Q96H78
EGIRGFYRGLTASYA

SLC25A33

181

Q9BSK2
AGRGNYDAFRGQGGY

SRRT

831

Q9BXP5
RGYGGNRFESRSGGY

CIRBP

121

Q14011
QPVRGYYRGAVGGTF

COASY

186

Q13057
AGYYQESGRAGRDGK

RECQL5

341

O94762
GYAALVASGGIIGYV

TMEM14C

16

Q9P0S9
GVYTGLGYVQAFLGG

SLC35G4

186

P0C7Q5
GTFYARERLGAVYGF

UBXN6

351

Q9BZV1
GSYGVVYEAVAGRSG

STK35

211

Q8TDR2
YEIGGLFGTGIRSYF

TMC8

96

Q8IU68
GGGGRYEEYQGRSLD

RBMXL3

466

Q8N7X1
SHRYGGGGRYEEYRG

RBMXL3

621

Q8N7X1
RYGGGGRYEEYRGHS

RBMXL3

701

Q8N7X1
RGSRYDGQIAVFGAG

UBA7

411

P41226
GRGVRLYYIGGEVFA

SMAD3

291

P84022
YVLVIFGGVIGYSGD

STT3B

656

Q8TCJ2
IATNGFVRGGGAYYL

SLC12A2

341

P55011
RYGGETKVYVGNLGT

SRSF7

6

Q16629
GAGKGELERAFSYYG

SRSF7

21

Q16629
GSYGVAGNVFIDSGR

MID1

526

O15344
RGYKGTQVSGVGIDY

THBS3

346

P49746
GVYTALGYGQAFVGG

SLC35G6

186

P0C7Q6
KRGDGTRGVTGYFTF

PSG2

126

P11465
TYGVEYTGDGGRAGT

PTPRH

151

Q9HD43
SSLGGRDLYRSGYGF

ZNF326

81

Q5BKZ1
GGLLYAVGGYDGASR

KLHL2

446

O95198
NRIGAGGIDGYLVEY

MYBPC2

761

Q14324