Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein-glutamine gamma-glutamyltransferase activity

TGM2 F13A1

3.59e-049642GO:0003810
GeneOntologyMolecularFunctionhistone binding

BPTF L3MBTL1 CHD5 NAP1L1 BAZ1B

1.60e-03265645GO:0042393
GeneOntologyMolecularFunction3',5'-cyclic-AMP phosphodiesterase activity

PDE6A PDE9A

2.24e-0322642GO:0004115
GeneOntologyMolecularFunctionmethylated histone binding

BPTF L3MBTL1 CHD5

2.66e-0386643GO:0035064
GeneOntologyMolecularFunction3',5'-cyclic-GMP phosphodiesterase activity

PDE6A PDE9A

2.67e-0324642GO:0047555
GeneOntologyMolecularFunctionmethylation-dependent protein binding

BPTF L3MBTL1 CHD5

2.84e-0388643GO:0140034
GeneOntologyMolecularFunction3',5'-cyclic-nucleotide phosphodiesterase activity

PDE6A PDE9A

2.89e-0325642GO:0004114
GeneOntologyMolecularFunctioncyclic-nucleotide phosphodiesterase activity

PDE6A PDE9A

3.37e-0327642GO:0004112
GeneOntologyMolecularFunctionATP-dependent activity

ACSL6 BPTF UBA7 KIF26B CHD5 CHD9 HSP90AA2P

3.42e-03614647GO:0140657
DomainDDT

BPTF BAZ1B

1.15e-045642SM00571
DomainWSD

BPTF BAZ1B

1.15e-045642PF15613
DomainWHIM1

BPTF BAZ1B

1.15e-045642PF15612
DomainDDT_dom

BPTF BAZ1B

1.15e-045642IPR018501
DomainWHIM1_dom

BPTF BAZ1B

1.15e-045642IPR028942
DomainWHIM2_dom

BPTF BAZ1B

1.15e-045642IPR028941
DomainDDT

BPTF BAZ1B

1.72e-046642PS50827
DomainTransglut_N

TGM2 F13A1

4.10e-049642PF00868
DomainTRANSGLUTAMINASES

TGM2 F13A1

4.10e-049642PS00547
DomainTransglutaminase_N

TGM2 F13A1

4.10e-049642IPR001102
DomainTransglut_C

TGM2 F13A1

4.10e-049642PF00927
Domain-

TGM2 F13A1

4.10e-0496423.90.260.10
DomainGln_gamma-glutamylTfrase_euk

TGM2 F13A1

4.10e-049642IPR023608
DomainTransglutaminase_AS

TGM2 F13A1

4.10e-049642IPR013808
DomainTransglutaminase_C

TGM2 F13A1

5.11e-0410642IPR008958
DomainTGc

TGM2 F13A1

6.23e-0411642SM00460
DomainTransglut_core

TGM2 F13A1

6.23e-0411642PF01841
DomainTransglutaminase-like

TGM2 F13A1

6.23e-0411642IPR002931
DomainZinc_finger_PHD-type_CS

BPTF CHD5 BAZ1B

1.44e-0365643IPR019786
DomainPDEase

PDE6A PDE9A

1.90e-0319642IPR023088
DomainPHD

BPTF CHD5 BAZ1B

2.17e-0375643PF00628
DomainPDEase_I

PDE6A PDE9A

2.33e-0321642PF00233
DomainPDEASE_I

PDE6A PDE9A

2.33e-0321642PS00126
DomainPDEase_CS

PDE6A PDE9A

2.33e-0321642IPR023174
DomainZnf_PHD-finger

BPTF CHD5 BAZ1B

2.52e-0379643IPR019787
Domain-

PDE6A PDE9A

2.55e-03226421.10.1300.10
DomainPDEase_catalytic_dom

PDE6A PDE9A

2.79e-0323642IPR002073
DomainHDc

PDE6A PDE9A

3.04e-0324642SM00471
DomainHD/PDEase_dom

PDE6A PDE9A

3.04e-0324642IPR003607
DomainChromo_domain

CHD5 CHD9

3.04e-0324642IPR023780
DomainPHD

BPTF CHD5 BAZ1B

3.53e-0389643SM00249
DomainBromodomain_CS

BPTF BAZ1B

3.56e-0326642IPR018359
DomainChromo

CHD5 CHD9

3.56e-0326642PF00385
DomainZnf_PHD

BPTF CHD5 BAZ1B

3.76e-0391643IPR001965
DomainCHROMO_1

CHD5 CHD9

4.13e-0328642PS00598
DomainCHROMO_2

CHD5 CHD9

4.13e-0328642PS50013
DomainZF_PHD_2

BPTF CHD5 BAZ1B

4.24e-0395643PS50016
DomainZF_PHD_1

BPTF CHD5 BAZ1B

4.37e-0396643PS01359
DomainSNF2_N

CHD5 CHD9

5.37e-0332642IPR000330
DomainChromodomain-like

CHD5 CHD9

5.37e-0332642IPR016197
DomainSNF2_N

CHD5 CHD9

5.37e-0332642PF00176
DomainChromo/shadow_dom

CHD5 CHD9

5.70e-0333642IPR000953
DomainCHROMO

CHD5 CHD9

5.70e-0333642SM00298
DomainMAGE

MAGEA10 NSMCE3

6.04e-0334642SM01373
DomainMAGE

MAGEA10 NSMCE3

6.76e-0336642PS50838
DomainMAGE

MAGEA10 NSMCE3

6.76e-0336642PF01454
DomainMHD_dom

MAGEA10 NSMCE3

6.76e-0336642IPR002190
Pubmed

Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunction.

PCSK5 TGM2 TNFSF10 C7 LY75 F13A1

4.68e-0810565624667918
Pubmed

Spatial transcriptomics identifies spatially dysregulated expression of GRM3 and USP47 in amyotrophic lateral sclerosis.

GRM3 USP47

3.44e-06265231925813
Pubmed

KCNK5 Regulating Potassium Efflux and Inducing Pyroptosis in Corneal Epithelial Cells Through TNFSF10-Mediated Autophagy in Dry Eye.

TNFSF10 KCNK5

3.44e-06265238236186
Pubmed

Factor XIIIA mobilizes transglutaminase 2 to induce chondrocyte hypertrophic differentiation.

TGM2 F13A1

3.44e-06265218544639
Pubmed

Role of transglutaminases in cuff-induced atherosclerotic lesion formation in femoral arteries of ApoE3 Leiden mice.

TGM2 F13A1

3.44e-06265220810110
Pubmed

Reactivity of the N-terminal region of fibronectin protein to transglutaminase 2 and factor XIIIA.

TGM2 F13A1

3.44e-06265221757696
Pubmed

Impaired clot retraction in factor XIII A subunit-deficient mice.

TGM2 F13A1

3.44e-06265219996413
Pubmed

Transglutaminase activity regulates osteoblast differentiation and matrix mineralization in MC3T3-E1 osteoblast cultures.

TGM2 F13A1

3.44e-06265216469487
Pubmed

Expression and localization of plasma transglutaminase factor XIIIA in bone.

TGM2 F13A1

3.44e-06265217341477
Pubmed

Transglutaminases in mineralized tissues.

TGM2 F13A1

3.44e-06265216368540
Pubmed

Cystatin D (CST5): An ultra-early inflammatory biomarker of traumatic brain injury.

TNFSF10 AXIN1

1.03e-05365228694499
Pubmed

Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow.

TGM2 F13A1

1.03e-05365228387755
Pubmed

Transglutaminase 2 and Factor XIII catalyze distinct substrates in differentiating osteoblastic cell line: utility of highly reactive substrate peptides.

TGM2 F13A1

1.03e-05365222045386
Pubmed

Cross-linking of wild-type and mutant alpha 2-antiplasmins to fibrin by activated factor XIII and by a tissue transglutaminase.

TGM2 F13A1

1.03e-05365210958788
Pubmed

USP47 Promotes Tumorigenesis by Negative Regulation of p53 through Deubiquitinating Ribosomal Protein S2.

MDM2 USP47

1.03e-05365232370049
Pubmed

MicroRNA-101-3p Suppresses Cancer Cell Growth by Inhibiting the USP47-Induced Deubiquitination of RPL11.

MDM2 USP47

1.03e-05365235205710
Pubmed

Assessment of expression and specific activities of transglutaminases TG1, TG2, and FXIII-A during osteoclastogenesis.

TGM2 F13A1

1.03e-05365231786225
Pubmed

Arterial vimentin is a transglutaminase substrate: a link between vasomotor activity and remodeling?

TGM2 F13A1

1.03e-05365217476115
Pubmed

FXIIIA and TGF-beta over-expression produces normal musculo-skeletal phenotype in TG2-/- mice.

TGM2 F13A1

1.03e-05365218594942
Pubmed

TWIK-related acid-sensitive K+ channel 2 promotes renal fibrosis by inducing cell-cycle arrest.

KCNK5 FTO

1.03e-05365236465115
Pubmed

The hypothalamic RFamide, QRFP, increases feeding and locomotor activity: The role of Gpr103 and orexin receptors.

QRFPR HCRTR1

1.03e-05365236251705
Pubmed

Normal Bone Deposition Occurs in Mice Deficient in Factor XIII-A and Transglutaminase 2.

TGM2 F13A1

1.03e-05365225680676
Pubmed

Cre/lox Studies Identify Resident Macrophages as the Major Source of Circulating Coagulation Factor XIII-A.

MPL F13A1

1.03e-05365228596376
Pubmed

Transglutaminase 2 limits the extravasation and the resultant myocardial fibrosis associated with factor XIII-A deficiency.

TGM2 F13A1

1.03e-05365231874419
Pubmed

MDM2 Inhibits Axin-Induced p53 Activation Independently of its E3 Ligase Activity.

MDM2 AXIN1

2.06e-05465223826318
Pubmed

Variant mapping and mutation discovery in inbred mice using next-generation sequencing.

PCSK5 ADAR

2.06e-05465226552429
Pubmed

alpha(2)-plasmin inhibitor is a substrate for tissue transglutaminase: an in vitro study.

TGM2 F13A1

2.06e-05465210963790
Pubmed

Renal cell carcinoma escapes death by p53 depletion through transglutaminase 2-chaperoned autophagy.

TGM2 MDM2

2.06e-05465227031960
Pubmed

Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.

BPTF OSBPL9 ALS2 FAM47E DEPDC7 ELOF1

3.36e-0532665617015433
Pubmed

Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretion.

MPL F13A1

3.43e-05565220086247
Pubmed

Epidermal growth factor receptor-mediated tissue transglutaminase overexpression couples acquired tumor necrosis factor-related apoptosis-inducing ligand resistance and migration through c-FLIP and MMP-9 proteins in lung cancer cells.

TGM2 TNFSF10

3.43e-05565221525012
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DCP1B TRIO KIF26B CEP192 AXIN1

4.60e-0520965536779422
Pubmed

ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.

FBN2 L3MBTL1 CHD5 CHD9

6.14e-0511365434474245
Pubmed

Focal amplifications are associated with high grade and recurrences in stage Ta bladder carcinoma.

MDM2 MYBL2

7.18e-05765219821490
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

FBN2 TRIO NAP1L1 MAGI3 CEP192 SEPTIN7 USP47 KLHL22

1.86e-0485365828718761
Pubmed

Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2.

MDM2 KLHL22

1.87e-041165237379210
Pubmed

Pathway analysis in HEK 293T cells overexpressing HIV-1 tat and nucleocapsid.

PCSK5 NAP1L1

2.65e-041365219884766
Pubmed

Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases.

PDE6A PDE9A

2.65e-04136528557689
Pubmed

FoxN1 mediates thymic cortex-medulla differentiation through modifying a developmental pattern based on epithelial tubulogenesis.

TNFRSF11A LY75

3.56e-041565231552487
Pubmed

Common body mass index-associated variants confer risk of extreme obesity.

FBN2 FTO

3.56e-041565219553259
Pubmed

Cell-free cotranslation and selection using in vitro virus for high-throughput analysis of protein-protein interactions and complexes.

MDM2 ELOF1

4.06e-041665215867431
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

MIER2 BPTF NAP1L1 KCNK5 FTO MYBL2

4.99e-0453665615840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

MIER2 BPTF NAP1L1 KCNK5 FTO MYBL2

5.08e-0453865610512203
Pubmed

Single nucleotide polymorphisms in the Wnt and BMP pathways and colorectal cancer risk in a Spanish cohort.

ADAR AXIN1

5.16e-041865220844743
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

BPTF OSBPL9 OGDHL ALS2 MDM2

5.96e-0436365514691545
Pubmed

Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.

ZNF283 ZNF229

6.39e-042065212743021
Pubmed

Dorsal root ganglion axon bifurcation tolerates increased cyclic GMP levels: the role of phosphodiesterase 2A and scavenger receptor Npr3.

PDE6A PDE9A

7.06e-042165227740716
Pubmed

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

DCP1B MRPL24 USP47 AXIN1

8.62e-0422665425900982
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MAGI3 ALS2 CEP192

9.11e-0410165310997877
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

MIER2 BPTF CHD5 BAZ1B CHD9 MYBL2

9.60e-0460865636089195
Pubmed

Overview of PDEs and their regulation.

PDE6A PDE9A

1.00e-032565217307970
Pubmed

Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis.

FAM20C FTO

1.00e-032565225085501
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PCSK5 FAM20C TRIO CHD5 KCNK5 OGDHL CEP192 MYBL2

1.03e-03110565835748872
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

BPTF UBA7 MDM2 MRPL24 ADAR USP47 MYBL2

1.08e-0385765725609649
Pubmed

Mapping Extracellular Protein-Protein Interactions Using Extracellular Proximity Labeling (ePL).

TGM2 FBN2 C7 F13A1

1.20e-0324765439238192
Pubmed

Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes.

MTARC1 USP47

1.26e-032865222118674
Pubmed

Human transcription factor protein interaction networks.

BPTF FBN2 DCP1B CHD5 BAZ1B CEP192 MDM2 MRPL24 MYBL2

1.31e-03142965935140242
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BPTF PDE9A TRIO AFF3 OSBPL9 MAGI3 CHD9 CEP192 MTARC1

1.74e-03148965928611215
Pubmed

Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.

MAGI3 USP47 AXIN1

1.80e-0312865325332235
Cytoband16q12.2

CHD9 FTO

6.28e-042665216q12.2
Cytoband19q13.31

ZNF283 ZNF229

7.82e-042965219q13.31
Cytoband2q33.1

STRADB ALS2

2.41e-03516522q33.1
GeneFamilyTransglutaminases

TGM2 F13A1

2.56e-049492773
GeneFamilyPHD finger proteins

BPTF CHD5 BAZ1B

1.86e-039049388
GeneFamilyPhosphodiesterases

PDE6A PDE9A

1.91e-0324492681
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Interneuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

SRRD PCSK5 TGM2 CHD5 C7 GRM3

4.75e-07200656a6500d0d2e8bcac92381ab771dbdee66b0e1d48e
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNFSF10 KIF26B AFF3 ALS2 NSMCE3

4.71e-06168655c7021748003e5949f7caf7b3291c5bad294948c1
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

ACSL6 TGM2 STRADB MINPP1 ELOF1

9.48e-06194655f0ababe8daa57f6827a3e2e72c884d9e8b2687a3
ToppCellMegakaryocytic-erythropoietic-Erythro-cells|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

ACSL6 TGM2 STRADB MINPP1 ELOF1

9.96e-06196655092caba6726d1acd409a8be335100764d0724e64
ToppCellLPS-IL1RA-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACSL6 STRADB RENBP F13A1

5.85e-051446547c471e332f87d60f4dbed01f3e66bf39995218d0
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TGM2 MAOB C7 MYBL2

7.04e-0515165432d35906f4b2bd46b173e87f2dec972eb5da87b3
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D122|Adult / Lineage, Cell type, age group and donor

RENBP TNFRSF11A DEPDC7 F13A1

1.02e-04166654be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCelldroplet-Lung-nan-21m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD5 FCRLB RENBP TNFRSF11A

1.19e-0417365431ea04e65876c42b90245d280f0b6439bfffbace
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAOB SYT9 TNFRSF11A F13A1

1.19e-041736545aa4d45a01d2d09eff8b4deb32bd91ab2471210a
ToppCelldroplet-Lung-nan-21m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD5 FCRLB RENBP TNFRSF11A

1.19e-041736541cff815536f620e32b9805666e1aa711462c2d25
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGM2 KCNK5 MAGI3 FAM47E

1.24e-041756546bb8fc2959583644f16b22e906af91af62a3a633
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGM2 KCNK5 MAGI3 FAM47E

1.24e-041756548902c38067f025b094ca9c28c449c32a66eded1c
ToppCelldroplet-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGM2 KCNK5 MAGI3 FAM47E

1.30e-04177654a5b54792ef948a1e1de66301a60e051250189f59
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

TGM2 MAOB C7 DEPDC7

1.30e-041776548220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

TGM2 MAOB C7 DEPDC7

1.30e-041776547617270f49cd6b7ba66db72d20560cee985012b2
ToppCelldroplet-Bladder-nan-24m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE6A FAM47E C7 GRM3

1.36e-04179654dfd9d29281510d32f1a2e8336d2e58ef496cfd1d
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-monocytoid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAM20C RENBP TNFRSF11A F13A1

1.39e-04180654ba4c1fb55e8f1095bea6968417fefcf5f700926b
ToppCell3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAOB ALS2 RENBP HCRTR1

1.39e-041806548bd9e12589bff64987bac30af4d2514ba6f09300
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FBN2 PRICKLE1 KIF26B SEPTIN7

1.42e-041816549b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-5|TCGA-Colorectal / Sample_Type by Project: Shred V9

IMPACT CEP192 TNFRSF11A MDM2

1.42e-041816548fcc9e77fee7c248df26b6c59b10e672242e2084
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

TRIO TNFSF10 CHD9 ADAR

1.48e-041836548f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellMS-IIF-Others-RBC|IIF / Disease, condition lineage and cell class

SRRD TGM2 STRADB GRM3

1.51e-04184654578bde79b464ed12dd9a53dd8e2839e156220a60
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

KIF26B CHD5 IMPACT HCRTR1

1.57e-041866549d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 QRFPR FBN2 KIF26B

1.60e-0418765485f1678338a47d91e296f0620d4887f057eb7e70
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

UBA7 PDE9A TNFSF10 ADAR

1.64e-041886546f8946d4710f6e32c937213f99b790b098b8819c
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic|GI_large-bowel / Manually curated celltypes from each tissue

FAM20C FBN2 TNFRSF11A F13A1

1.64e-04188654d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCell10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes|GI_large-bowel / Manually curated celltypes from each tissue

FAM20C FBN2 TNFRSF11A F13A1

1.64e-041886540bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCellInfluenza_Severe-RBC|World / Disease group and Cell class

ACSL6 TGM2 STRADB MINPP1

1.64e-04188654f0438e6a77ee1f0456cb65926685266fff470983
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

KIF26B CHD5 IMPACT HCRTR1

1.64e-04188654b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRIO PRICKLE1 TNFSF10 KIF26B

1.67e-041896543b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Mast_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAOB TNFSF10 ALS2 RENBP

1.67e-041896547bc6e152fb4fe5cd6db9407929c15843a5d8f8c4
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|World / Lineage, cell class and subclass

ACSL6 TGM2 STRADB MINPP1

1.67e-04189654826457adac7477102f86aceb97a8b77929b3e6f9
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

PCSK5 QRFPR TNFSF10 KCNK5

1.67e-041896540be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 PRICKLE1 AFF3 C7

1.67e-04189654c734e5693808a0333139e87bd5be2597a9252afe
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.71e-041906542306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellMegakaryocytic-erythropoietic-Erythro-cells|World / Lineage, cell class and subclass

ACSL6 TGM2 STRADB MINPP1

1.71e-041906546c7e016a9b425ee9418acd4fe96b9779fe7bd39a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 PRICKLE1 AFF3 C7

1.71e-041906542e592323085ba9c019d678ac2a784462ab470ed9
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPL TGM2 UBA7 TNFSF10

1.71e-0419065496a9756cad5468a12591021e6d661ed269b5b3d9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.71e-041906541f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

TGM2 MAOB NAP1L1 C7

1.71e-0419065471e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 PRICKLE1 AFF3 C7

1.71e-04190654445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellsevere_COVID-19-RBC|severe_COVID-19 / disease group, cell group and cell class (v2)

ACSL6 TGM2 STRADB MINPP1

1.71e-041906543a5723c2daf58c1932edd70910db4b8b30f63f42
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.74e-04191654a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 PRICKLE1 AFF3 C7

1.74e-04191654c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 PRICKLE1 AFF3 C7

1.74e-04191654806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellILEUM-non-inflamed-(6)_ILC3|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TGM2 PRICKLE1 AFF3 NAP1L1

1.74e-041916546eaf72b41084404bee0db04e4605db745a74995f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGM2 PRICKLE1 AFF3 C7

1.74e-04191654cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRIO PRICKLE1 TNFSF10 KIF26B

1.74e-041916541cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.74e-04191654107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.74e-04191654bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.78e-041926549093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.78e-041926549ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAOB TNFSF10 ALS2 RENBP

1.78e-041926549ad9dce4fcbb133b135079eb4cc32c7ead7f0243
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

TGM2 MAOB KIF26B NAP1L1

1.78e-0419265462904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIO AFF3 CHD9 MYBL2

1.81e-0419365408696a99309f5b088692ddac8cca35413b5e810d
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

TGM2 MAOB KIF26B C7

1.81e-04193654ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellMegakaryocytic-erythropoietic|World / Lineage, cell class and subclass

TGM2 STRADB MINPP1 F13A1

1.81e-04193654805c2e2e5d8a9df5ce796d5c0206d6493ab53c88
ToppCellControl-NK_CD56bright|Control / Disease condition and Cell class

KIF26B AFF3 CHD9 TNFRSF11A

1.81e-041936548b1e7a226a6057e1097c1525984127b54e823876
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 FBN2 KIF26B SYT9

1.85e-0419465483863da11dfbe59b2d0a2c08db40b537c150588c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.85e-04194654240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TGM2 MAOB KIF26B C7

1.85e-0419465435f132cc38ac133be01834ed0946188aa0757eb4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.85e-04194654ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

PCSK5 OSBPL9 CHD9 C7

1.85e-04194654234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.88e-04195654d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

PCSK5 OSBPL9 CHD9 C7

1.88e-04195654a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

TGM2 MAOB KIF26B C7

1.88e-04195654603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SYT9 TNFRSF11A F13A1 MYBL2

1.88e-0419565467b05a0cd2ca9924eca81a92cc6330eecb9d963c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.88e-0419565444d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.92e-04196654a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell15-Trachea-RBC-RBC|Trachea / Age, Tissue, Lineage and Cell class

ACSL6 STRADB MINPP1 MYBL2

1.92e-04196654511bfc06c34d5add2ae561cca463d1e4e2d43e20
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TGM2 MAOB NAP1L1 C7

1.92e-041966546730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

QRFPR FBN2 C7 NSMCE3

1.92e-04196654308fa54385ca34e9e590967d4553b84aad96c92f
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TGM2 MAOB NAP1L1 C7

1.92e-0419665421dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MAOB TNFSF10 ALS2 RENBP

1.92e-04196654e08f90f7a923c2846cac859519b8dc7c0ac7cd03
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.92e-04196654ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

TGM2 STRADB MINPP1 MYBL2

1.92e-04196654707eecbb2b14051fd843afa66035014ec59e6bd5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.92e-0419665430ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.92e-041966543e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic_early|bone_marrow / Manually curated celltypes from each tissue

TGM2 STRADB MINPP1 MYBL2

1.92e-04196654507254c4c00e535fe01851431b5b74a5f15d9592
ToppCell15-Trachea-RBC|Trachea / Age, Tissue, Lineage and Cell class

ACSL6 STRADB MINPP1 MYBL2

1.92e-04196654bf2670e5ae996a19987bc70aa5a37d133db789eb
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MAOB TNFSF10 ALS2 RENBP

1.92e-0419665403710e2a843279124a45a271bffb132835e6081c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.96e-041976546d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MAOB TNFSF10 ALS2 RENBP

1.96e-041976545e4a004052b8560223673a339d4a0d729e533def
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-mast_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAOB TNFSF10 ALS2 RENBP

1.96e-0419765461f909737c5f630beffdd326c6844215643dbdde
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.96e-04197654b349f8e96d61a4c296af64711e11fc44459a9413
ToppCelltumor_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

TGM2 MAOB NAP1L1 C7

1.96e-0419765444f37a98f07c3e46a7e8fd3b64c2b2b44d5bbe40
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE1 KIF26B AFF3 C7

1.96e-04197654c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

MAOB PRICKLE1 KIF26B C7

1.96e-04197654f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

TRIO AFF3 MAGI3 FTO

2.00e-041986541996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAOB TNFSF10 ALS2 RENBP

2.00e-04198654a1247a5efd92f95c6227c0e71dc8a0427eb54b7f
ToppCellControl-Control-Others-HSPC|Control / Disease, condition lineage and cell class

MPL FBXW9 KCNK5 MINPP1

2.04e-04199654b71169be0d916b2ed139a3122d78bb154c71edb4
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-dn_T|Bac-SEP / Disease, condition lineage and cell class

ACSL6 FCRLB FTO USP47

2.04e-041996544150a479b80596accf679b37aa9b0ac15cc132b2
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

TRIO AFF3 MAGI3 FTO

2.04e-0419965494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellInfluenza-Influenza_Severe-Others-RBC|Influenza_Severe / Disease, condition lineage and cell class

ACSL6 TGM2 STRADB MINPP1

2.04e-04199654da0fec0a492bc3827d9066d2590bcd466cd45564
ToppCell343B-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TGM2 MAOB NAP1L1 C7

2.04e-04199654212e89d097753790061310373a1fafba773488b6
ToppCell(7)_Mast_cell|World / shred on Cell_type and subtype

MAOB TNFSF10 ALS2 RENBP

2.04e-04199654c0b5f1cb435da99a7e2ebac9ee7d7b1bd0e49b42
ToppCell343B-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

TGM2 MAOB NAP1L1 C7

2.04e-0419965414b676aa289c0578a37be32cec3ea285c79d97cc
ToppCellCaecum-(7)_Mast_cell|Caecum / shred on region, Cell_type, and subtype

MAOB TNFSF10 ALS2 RENBP

2.08e-04200654d23fe8644ce42ace51fcde43cb4cd22a99300c02
ToppCellTransverse-(7)_Mast_cell-(70)_Mast|Transverse / shred on region, Cell_type, and subtype

MAOB TNFSF10 ALS2 RENBP

2.08e-04200654aa17354c83b0967707d995e4b74e042ac211f814
ToppCellSigmoid-(6)_Macrophage-(61)_LYVE1_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

FAM20C FBN2 TNFRSF11A F13A1

2.08e-04200654bc0280d52e4edc2c5edf4ead164a1c7cf3fccd60
Drug3,5-dinitrosalicylic acid hydrazide

FBN2 ADAR

8.03e-062652CID003663247
DrugMaprotiline hydrochloride [10347-81-6]; Up 200; 12.8uM; MCF7; HT_HG-U133A

TGM2 L3MBTL1 TNFSF10 KCNK5 F13A1 ANAPC13

1.82e-051926563236_UP
DrugChlorambucil [305-03-3]; Up 200; 13.2uM; MCF7; HT_HG-U133A

MPL MIER2 TGM2 KIF26B GRM3 F13A1

2.16e-051986564345_UP
DrugCyclacillin [3485-14-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

MPL PCSK5 FBN2 CHD5 MDM2 F13A1

2.16e-051986564358_UP
DrugIoversol [87771-40-2]; Down 200; 5uM; PC3; HT_HG-U133A

L3MBTL1 TRIO TNFSF10 SEPTIN7 MDM2 KLHL22

2.16e-051986566726_DN
Diseasepulmonary embolism (is_implicated_in)

FTO F13A1

4.61e-055642DOID:9477 (is_implicated_in)
DiseaseMood Disorders

MAOB FTO GRM3 HCRTR1

4.94e-04168644C0525045
Diseaseprotein C measurement

KCNK5 BAZ1B

6.17e-0417642EFO_0004633
Diseaseautoimmune thyroid disease, type 1 diabetes mellitus

QRFPR MAGI3

6.93e-0418642EFO_0006812, MONDO_0005147
Diseaseunipolar depression, bipolar disorder, schizophrenia

PCSK5 FTO

8.58e-0420642EFO_0003761, MONDO_0004985, MONDO_0005090
Diseasesurvival time, coronary artery disease

PDE9A KLHL22

1.94e-0330642EFO_0000714, EFO_0001645
Diseasearteriosclerosis (is_implicated_in)

TNFSF10 F13A1

2.07e-0331642DOID:2349 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
EWDLESLCVYEPDRN

AFF3

11

P51826
DLPYDQCTWEIDDID

CHD5

616

Q8TDI0
AVPADEKWKAVFDEC

ALS2

1286

Q96Q42
EVAELLKEEFPAWYE

BAZ1B

71

Q9UIG0
GCYDLPEDYIRWEDA

GRM3

561

Q14832
QEDEWLSAAIDCLEY

DEPDC7

261

Q96QD5
AELIDCLDKDYWEAE

BPTF

501

Q12830
ELYDLEETPVSWKDD

CBWD5

336

Q5RIA9
EPVDVYSDWIDACEA

ELOF1

66

P60002
DFLYEKEHICCLEEW

QRFPR

191

Q96P65
INAIYEPTEEECEWK

NAP1L1

121

P55209
EDGECWVYDEPLLKR

OSBPL9

716

Q96SU4
EALEPVHYEEKNWCE

MAOB

376

P27338
DEELAGKYAELGDWC

RENBP

206

P51606
EEKNFDWPAACIALE

FBXW9

136

Q5XUX1
FPLWYEEALKDEEER

MAGEA10

326

P43363
CEDGELPYGWEKIED

MAGI3

336

Q5TCQ9
CDVYAEDSWDELLIG

MTARC1

246

Q5VT66
ADQKPECRPYWEKDD

FTO

466

Q9C0B1
WELDSLEYLEALECV

KIF26B

2066

Q2KJY2
ELYDLEETPVSWKDD

CBWD2

336

Q8IUF1
ELYDLEETPVSWKDD

CBWD1

336

Q9BRT8
ANEKCSPSEYWDEDA

PCSK5

1451

Q92824
DRISEECEPWDAQDY

KCNK5

396

O95279
DPDNFCWEKYLEETG

L3MBTL1

486

Q9Y468
AEKYPGAELAWCQEE

OGDHL

931

Q9ULD0
TREVYGKEPWECEEE

PDE6A

471

P16499
EVAEPWVDCLLEEYF

PDE9A

471

O76083
YGWIVADDCDETEDK

LY75

51

O60449
NPWCEDDAVYLDNEK

F13A1

186

P00488
AIYGEEWCVIDDCAK

IMPACT

21

Q9P2X3
WYEDSLECLSDLKPE

PRICKLE1

516

Q96MT3
VCDERWADDLYPKIY

HCRTR1

201

O43613
GIWFYDKEECQRIAE

DCP1B

111

Q8IZD4
DDAWREDKLPYEDVA

ANAPC13

16

Q9BS18
CSLPYEDSTWELKED

CHD9

801

Q3L8U1
YDVEKDCWEEGPQLD

KLHL22

566

Q53GT1
VNWCLADGYDLEILD

ADAR

1126

P55265
KAEWEVDPDYCEEVK

FAM20C

416

Q8IXL6
GYLPTLNEDEEWKCD

AXIN1

236

O15169
LKWALEEYLDEFDPC

C7

441

P10643
ELYDLEETPVSWKDD

CBWD3

336

Q5JTY5
DYAQFWDVECHPLKE

CEP192

2361

Q8TEP8
EPEVEELESYWCEAA

FCRLB

256

Q6BAA4
EQCYLKWDEDECIHP

FBN2

1001

P35556
EEYGEFCKNLTNDWE

HSP90AA2P

306

Q14568
CEKIYENEDQLLWDP

MIER2

216

Q8N344
ADFPRECILWKDIEY

SYT9

331

Q86SS6
PDRKLEDTWAYCQDT

FAM47E

151

Q6ZV65
ESDPDAWCDLSKFDL

MYBL2

316

P10244
FEEDPEISLADYWKC

MDM2

291

Q00987
VEPISDEDWYLFCGD

MRPL24

46

Q96A35
LVDVEELNYWACKGE

ACSL6

491

Q9UKU0
ARDEYWKCLDENLED

COA6

61

Q5JTJ3
AWCPADAVYLDSEEE

TGM2

141

P21980
WCDVFDIDDAKVLEY

MINPP1

301

Q9UNW1
WLYFDALDCLPEDGE

UBA7

386

P41226
CWQPVIDYIDSKFED

SEPTIN7

126

Q16181
LYKWEFEESEEDPVT

USP47

216

Q96K76
WEFREEPDYQDCEDL

SRRD

311

Q9UH36
DRYPIWENCEEEEKT

MPL

326

P40238
KDWPAQYCEALADEE

NSMCE3

276

Q96MG7
LDTEDTVYKCNWDDD

ZNF229

206

Q9UJW7
WTEPECDFPDEKDSY

STRADB

401

Q9C0K7
CFLKEDDSYWDPNDE

TNFSF10

56

P50591
EQEYKREEDWCGGAD

TRIO

1031

O75962
CGPDEYLDSWNEEDK

TNFRSF11A

71

Q9Y6Q6
EWECLDPAQRDLYVD

ZNF283

86

Q8N7M2
CEIEELSPKWFIDED

ZNF527

91

Q8NB42