Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.31e-125965GO:0052871
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.82e-117965GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.82e-117965GO:0018685
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.72e-1010965GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.72e-1010965GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.72e-1010965GO:0102033
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.89e-0913965GO:0016713
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

9.14e-0824965GO:0008392
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.72e-0727965GO:0008391
GeneOntologyMolecularFunctionarachidonate binding

CYP4F8 CYP4F2 CYP4F12 CYP4F11

6.58e-0715964GO:0050544
GeneOntologyMolecularFunctionaromatase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.70e-0735965GO:0070330
GeneOntologyMolecularFunctionicosanoid binding

CYP4F8 CYP4F2 CYP4F12 CYP4F11

8.73e-0716964GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F8 CYP4F2 CYP4F12 CYP4F11

8.73e-0716964GO:0050543
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.33e-0640965GO:0016709
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.73e-0649965GO:0016712
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4F8 CYP4F2 CYP4F12 CYP4F11

9.40e-0628964GO:0036041
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

2.29e-052962GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

2.29e-052962GO:0097259
GeneOntologyMolecularFunctionnitrate reductase activity

GPHN MTARC1

6.84e-053962GO:0008940
GeneOntologyMolecularFunctionheme binding

CYP4F8 CYP4F2 TDO2 CYP4F3 CYP4F12 CYP4F11

9.99e-05154966GO:0020037
GeneOntologyMolecularFunctionactin filament binding

SYNE1 SPTA1 SPTAN1 VPS16 MACF1 EPS8L3 MYO18B

1.13e-04227967GO:0051015
GeneOntologyMolecularFunctiontetrapyrrole binding

CYP4F8 CYP4F2 TDO2 CYP4F3 CYP4F12 CYP4F11

1.41e-04164966GO:0046906
GeneOntologyMolecularFunctionsyntaxin-1 binding

STXBP1 STXBP2 STXBP3

2.03e-0424963GO:0017075
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

2.27e-045962GO:0140444
GeneOntologyMolecularFunctioncytoskeletal protein binding

GPHN SYNE1 SPTA1 SPTAN1 CKAP5 TOGARAM1 VPS16 KATNAL1 PRC1 TTLL7 DLC1 SYNE2 MACF1 EPS8L3 MYO18B

2.31e-0410999615GO:0008092
GeneOntologyMolecularFunctionmonooxygenase activity

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.34e-04115965GO:0004497
GeneOntologyMolecularFunctionmolybdopterin cofactor binding

GPHN MTARC1

3.39e-046962GO:0043546
GeneOntologyMolecularFunctionfatty acid binding

CYP4F8 CYP4F2 CYP4F12 CYP4F11

3.41e-0469964GO:0005504
GeneOntologyMolecularFunctionsyntaxin binding

STXBP1 STXBP2 STXBP3 BAIAP3

8.23e-0487964GO:0019905
GeneOntologyMolecularFunctionlipid binding

CYP4F8 PSD2 CYP4F2 MYOF ESYT2 CHMP4A DLC1 NFE2L1 ZFYVE26 CYP4F12 BAIAP3 CYP4F11 ARAP2

8.79e-049889613GO:0008289
GeneOntologyMolecularFunctioniron ion binding

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.24e-03166965GO:0005506
GeneOntologyMolecularFunctionmonocarboxylic acid binding

CYP4F8 CYP4F2 CYP4F12 CYP4F11

1.77e-03107964GO:0033293
GeneOntologyMolecularFunctionactin binding

SYNE1 SPTA1 SPTAN1 VPS16 SYNE2 MACF1 EPS8L3 MYO18B

2.17e-03479968GO:0003779
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.46e-03194965GO:0016705
GeneOntologyMolecularFunctionoxidoreductase activity, acting on other nitrogenous compounds as donors

GPHN MTARC1

2.97e-0317962GO:0016661
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RALGAPA1 PSD2 ECT2 ARHGEF15 ARHGEF40 DLC1 EPS8L3 ARAP2

3.08e-03507968GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RALGAPA1 PSD2 ECT2 ARHGEF15 ARHGEF40 DLC1 EPS8L3 ARAP2

3.08e-03507968GO:0030695
GeneOntologyMolecularFunctionintracellularly calcium-gated channel activity

CLCA2 ANO7

4.11e-0320962GO:0141147
GeneOntologyMolecularFunctionintracellularly calcium-gated chloride channel activity

CLCA2 ANO7

4.11e-0320962GO:0005229
GeneOntologyMolecularFunctionSNARE binding

STXBP1 STXBP2 STXBP3 BAIAP3

4.22e-03136964GO:0000149
GeneOntologyMolecularFunctionprotein dimerization activity

RALGAPA1 ZNF862 SYNE1 CASQ2 ECT2 TRIM5 CHMP4A NFE2L1 SUPT5H ANO7 ATIC ABCG8 TOP2A

5.00e-0312059613GO:0046983
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

PSD2 ECT2 ARHGEF15 ARHGEF40 EPS8L3

5.17e-03231965GO:0005085
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.11e-116955GO:0036101
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.88e-117955GO:0036102
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.03e-108955GO:0036100
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

8.42e-1011955GO:1901523
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.44e-0912955GO:0042758
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.61e-0822955GO:1901569
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F2 CYP4F12 CYP4F11

9.47e-083953GO:0042361
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F2 CYP4F12 CYP4F11

3.77e-074953GO:0009233
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F2 CYP4F12 CYP4F11

3.77e-074953GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F2 CYP4F12 CYP4F11

3.77e-074953GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F2 CYP4F12 CYP4F11

3.77e-074953GO:0042377
GeneOntologyBiologicalProcessomega-hydroxylase P450 pathway

CYP4F8 CYP4F2 CYP4F12 CYP4F11

4.08e-0714954GO:0097267
GeneOntologyBiologicalProcessleukotriene metabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.22e-0641955GO:0006691
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F2 CYP4F12 CYP4F11

1.87e-066953GO:1905344
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F2 CYP4F12 CYP4F11

1.87e-066953GO:0062232
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

CYP4F8 CYP4F2 FAR2 CYP4F3 CYP4F12 CYP4F11

2.15e-0682956GO:1901568
GeneOntologyBiologicalProcessregulation of organelle organization

ERCC4 SYNE1 SPTA1 SPTAN1 CKAP5 BAZ1B TOGARAM1 ECT2 ARHGEF15 CHMP4A DLC1 STXBP1 AKAP9 NFE2L1 ARID2 SYNE2 PLAUR MAPK9 TOP2A

9.76e-0613429519GO:0033043
GeneOntologyBiologicalProcessvitamin K metabolic process

CYP4F2 CYP4F12 CYP4F11

1.52e-0511953GO:0042373
GeneOntologyBiologicalProcessarachidonate metabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.54e-0568955GO:0019369
GeneOntologyBiologicalProcesscentrosome localization

SYNE1 CCDC141 AKAP9 SYNE2

1.98e-0535954GO:0051642
GeneOntologyBiologicalProcessfat-soluble vitamin catabolic process

CYP4F2 CYP4F12 CYP4F11

2.02e-0512953GO:0042363
GeneOntologyBiologicalProcessregulation of nucleus organization

SYNE1 NFE2L1

2.10e-052952GO:1903353
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.19e-0573955GO:1901616
GeneOntologyBiologicalProcessmicrotubule organizing center localization

SYNE1 CCDC141 AKAP9 SYNE2

2.22e-0536954GO:0061842
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

SYNE1 SPTA1 SPTAN1 CKAP5 TOGARAM1 VPS16 ECT2 TRIM5 ARHGEF15 CHMP4A DLC1 STXBP1 AKAP9 SYNE2 MACF1 EPS8L3 MAPK9

2.73e-0511899517GO:0044087
GeneOntologyBiologicalProcessunsaturated fatty acid metabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 MAPK9 CYP4F11

2.81e-05128956GO:0033559
GeneOntologyBiologicalProcessorganelle localization by membrane tethering

ESYT2 STXBP1 STXBP2 STXBP3 EXOC2

4.57e-0585955GO:0140056
GeneOntologyBiologicalProcessvesicle docking involved in exocytosis

STXBP1 STXBP2 STXBP3 EXOC2

4.98e-0544954GO:0006904
GeneOntologyBiologicalProcessicosanoid metabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 MAPK9 CYP4F11

5.03e-05142956GO:0006690
GeneOntologyBiologicalProcessmembrane docking

ESYT2 STXBP1 STXBP2 STXBP3 EXOC2

6.34e-0591955GO:0022406
GeneOntologyBiologicalProcessvitamin catabolic process

CYP4F2 CYP4F12 CYP4F11

7.35e-0518953GO:0009111
GeneOntologyBiologicalProcessketone catabolic process

CYP4F2 CYP4F12 CYP4F11

1.19e-0421953GO:0042182
GeneOntologyBiologicalProcessprotein polymerization

SPTA1 SPTAN1 CKAP5 CASQ1 TOGARAM1 CASQ2 CHMP4A AKAP9

1.56e-04334958GO:0051258
GeneOntologyBiologicalProcessfatty acid catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.00e-04116955GO:0009062
GeneOntologyBiologicalProcessvesicle docking

STXBP1 STXBP2 STXBP3 EXOC2

2.31e-0465954GO:0048278
GeneOntologyBiologicalProcesslong-chain fatty acid metabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.72e-04124955GO:0001676
GeneOntologyBiologicalProcessvitamin E metabolic process

CYP4F2 CYP4F12

3.11e-046952GO:0042360
GeneOntologyBiologicalProcesscell division

CKAP5 PRC1 ECT2 LIG3 CHMP4A LATS2 ZFYVE26 ANAPC16 EXOC2 TOP2A TDRD12

3.60e-046979511GO:0051301
GeneOntologyBiologicalProcessorganelle localization

SYNE1 ECT2 ESYT2 CHMP4A STXBP1 STXBP2 AKAP9 STXBP3 SYNE2 EXOC2 BAIAP3

3.87e-047039511GO:0051640
GeneOntologyBiologicalProcessregulation of protein-containing complex assembly

SPTA1 SPTAN1 CKAP5 TOGARAM1 VPS16 TRIM5 STXBP1 AKAP9 MAPK9

4.25e-04489959GO:0043254
GeneOntologyBiologicalProcessmonocarboxylic acid catabolic process

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.59e-04145955GO:0072329
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization

CKAP5 TOGARAM1 AKAP9

6.57e-0437953GO:0031116
GeneOntologyBiologicalProcessactomyosin structure organization

CASQ1 CASQ2 ECT2 ARHGEF15 DLC1 MYO18B

8.37e-04239956GO:0031032
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

RALGAPA1 PSD2 ECT2 ARHGEF15 ARHGEF40 DLC1 EPS8L3

8.80e-04333957GO:0051056
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization or depolymerization

CKAP5 TOGARAM1 AKAP9

9.54e-0442953GO:0031112
GeneOntologyBiologicalProcessmitotic cytokinesis

ECT2 CHMP4A ZFYVE26 EXOC2

9.76e-0495954GO:0000281
GeneOntologyBiologicalProcessendomembrane system organization

SYNE1 SPTA1 CASQ1 MYOF ESYT2 CHMP4A STXBP1 AKAP9 ANO7 BAIAP3

1.06e-036729510GO:0010256
GeneOntologyCellularComponentsupramolecular fiber

KRT14 SYNE1 SPTAN1 CKAP5 CASQ1 TOGARAM1 CASQ2 VPS16 KATNAL1 PRC1 TTLL7 CHMP4A DLC1 SYNE2 MACF1 MYO18B

5.91e-0511799316GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KRT14 SYNE1 SPTAN1 CKAP5 CASQ1 TOGARAM1 CASQ2 VPS16 KATNAL1 PRC1 TTLL7 CHMP4A DLC1 SYNE2 MACF1 MYO18B

6.41e-0511879316GO:0099081
GeneOntologyCellularComponentcondensed chromosome

NUP107 CKAP5 BAZ1B LIG3 CHMP4A ARID2 ANAPC16 TOP2A

6.82e-05307938GO:0000793
GeneOntologyCellularComponentchromosome, centromeric region

NUP107 CKAP5 BAZ1B CHMP4A ARID2 ANAPC16 TOP2A

2.33e-04276937GO:0000775
GeneOntologyCellularComponentmidbody

SYNE1 PRC1 ECT2 CHMP4A ZFYVE26 EXOC2

4.74e-04222936GO:0030496
GeneOntologyCellularComponentintraciliary transport particle A

TTC21A TTC21B

5.39e-048932GO:0030991
GeneOntologyCellularComponentZ disc

SPTAN1 CASQ1 CASQ2 SYNE2 MYO18B

5.74e-04151935GO:0030018
GeneOntologyCellularComponentchromosomal region

ERCC4 NUP107 CKAP5 BAZ1B CHMP4A ARID2 ANAPC16 TOP2A

5.80e-04421938GO:0098687
GeneOntologyCellularComponentsarcoplasmic reticulum lumen

CASQ1 CASQ2

6.91e-049932GO:0033018
GeneOntologyCellularComponentspectrin

SPTA1 SPTAN1

6.91e-049932GO:0008091
GeneOntologyCellularComponentspecific granule

SPTAN1 STXBP2 STXBP3 PLAUR MMP8

7.46e-04160935GO:0042581
GeneOntologyCellularComponentsarcomere

SYNE1 SPTAN1 CASQ1 CASQ2 SYNE2 MYO18B

8.64e-04249936GO:0030017
GeneOntologyCellularComponentI band

SPTAN1 CASQ1 CASQ2 SYNE2 MYO18B

8.80e-04166935GO:0031674
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 SYNE2

1.05e-0311932GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 SYNE2

1.05e-0311932GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 SYNE2

1.05e-0311932GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 SYNE2

1.05e-0311932GO:0106094
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

CASQ1 CASQ2 SYNE2

1.06e-0345933GO:0033017
GeneOntologyCellularComponentkinetochore

NUP107 CKAP5 CHMP4A ARID2 ANAPC16

1.29e-03181935GO:0000776
GeneOntologyCellularComponentcell cortex

SPTA1 SPTAN1 ECT2 DLC1 STXBP1 MACF1 EXOC2

1.34e-03371937GO:0005938
GeneOntologyCellularComponentruffle membrane

PSD2 DLC1 MACF1 EPS8L3

1.38e-03108934GO:0032587
GeneOntologyCellularComponentmyofibril

SYNE1 SPTAN1 CASQ1 CASQ2 SYNE2 MYO18B

1.39e-03273936GO:0030016
GeneOntologyCellularComponentcytoplasmic side of plasma membrane

GPHN SPTA1 SYAP1 ESYT2 CHMP4A

1.43e-03185935GO:0009898
GeneOntologyCellularComponentapical plasma membrane

CYP4F8 CYP4F2 STXBP2 STXBP3 CYP4F3 CYP4F12 CYP4F11 ABCG8

1.48e-03487938GO:0016324
GeneOntologyCellularComponentcuticular plate

SPTA1 SPTAN1

1.48e-0313932GO:0032437
GeneOntologyCellularComponentcondensed chromosome, centromeric region

NUP107 CKAP5 CHMP4A ARID2 ANAPC16

1.72e-03193935GO:0000779
GeneOntologyCellularComponentcontractile muscle fiber

SYNE1 SPTAN1 CASQ1 CASQ2 SYNE2 MYO18B

1.88e-03290936GO:0043292
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KRT14 CKAP5 TOGARAM1 VPS16 KATNAL1 PRC1 TTLL7 CHMP4A DLC1 MACF1 MYO18B

2.14e-038999311GO:0099513
GeneOntologyCellularComponentleading edge membrane

PSD2 DLC1 SYNE2 MACF1 EPS8L3

2.48e-03210935GO:0031256
GeneOntologyCellularComponentmicrotubule organizing center

CKAP5 TOGARAM1 KATNAL1 CCDC141 ECT2 TTLL7 MYOF LATS2 AKAP9 ZFYVE26 TOP2A

2.54e-039199311GO:0005815
GeneOntologyCellularComponentcytoplasmic side of membrane

GPHN SPTA1 SYAP1 ESYT2 CHMP4A

3.66e-03230935GO:0098562
GeneOntologyCellularComponentextrinsic component of membrane

GPHN ARHGEF40 STXBP1 AKAP9 PLAUR

3.66e-03230935GO:0019898
GeneOntologyCellularComponentlate endosome

VPS16 ANKRD13A CHMP4A ABCA5 ZFYVE26 BAIAP3

4.62e-03348936GO:0005770
GeneOntologyCellularComponentapical part of cell

CYP4F8 CYP4F2 STXBP2 STXBP3 CYP4F3 CYP4F12 CYP4F11 ABCG8

4.88e-03592938GO:0045177
HumanPhenoSudden cardiac death

SYNE1 BAZ1B CASQ2 AKAP9 SYNE2 PPA2 ABCG8

1.23e-05112377HP:0001645
HumanPhenoSudden death

SYNE1 BAZ1B CASQ2 AKAP9 SYNE2 PPA2 ABCG8

3.43e-05131377HP:0001699
DomainSpectrin

SYNE1 SPTA1 SPTAN1 CCDC141 SYNE2 MACF1

1.79e-0923996PF00435
DomainSpectrin_repeat

SYNE1 SPTA1 SPTAN1 CCDC141 SYNE2 MACF1

8.19e-0929996IPR002017
DomainSpectrin/alpha-actinin

SYNE1 SPTA1 SPTAN1 SYNE2 MACF1

6.79e-0732995IPR018159
DomainSPEC

SYNE1 SPTA1 SPTAN1 SYNE2 MACF1

6.79e-0732995SM00150
DomainCyt_P450_E_grp-I

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.90e-0645995IPR002401
DomainSec1

STXBP1 STXBP2 STXBP3

7.94e-068993PF00995
DomainSec1-like

STXBP1 STXBP2 STXBP3

7.94e-068993IPR001619
Domain-

STXBP1 STXBP2 STXBP3

7.94e-0689933.40.50.1910
DomainSec-1-like_dom2

STXBP1 STXBP2 STXBP3

7.94e-068993IPR027482
DomainCyt_P450_CS

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

8.86e-0653995IPR017972
DomainCYTOCHROME_P450

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.27e-0557995PS00086
Domain-

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.39e-05589951.10.630.10
Domainp450

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.39e-0558995PF00067
DomainCyt_P450

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.64e-0560995IPR001128
DomainCALSEQUESTRIN_1

CASQ1 CASQ2

2.78e-052992PS00863
DomainCALSEQUESTRIN_2

CASQ1 CASQ2

2.78e-052992PS00864
DomainCalsequestrin_CS

CASQ1 CASQ2

2.78e-052992IPR018233
DomainCalsequestrin

CASQ1 CASQ2

2.78e-052992PF01216
DomainKASH

SYNE1 SYNE2

1.66e-044992PF10541
DomainKASH

SYNE1 SYNE2

1.66e-044992IPR012315
DomainKASH

SYNE1 SYNE2

1.66e-044992PS51049
DomainCalsequestrin

CASQ1 CASQ2

1.66e-044992IPR001393
DomainKASH

SYNE1 SYNE2

1.66e-044992SM01249
DomainActinin_actin-bd_CS

SYNE1 SYNE2 MACF1

2.37e-0423993IPR001589
DomainACTININ_2

SYNE1 SYNE2 MACF1

2.37e-0423993PS00020
DomainACTININ_1

SYNE1 SYNE2 MACF1

2.37e-0423993PS00019
DomainEF-hand_Ca_insen

SPTA1 SPTAN1

4.11e-046992IPR014837
DomainEFhand_Ca_insen

SPTA1 SPTAN1

4.11e-046992PF08726
DomainTUDOR

TDRD15 TDRD12

2.43e-0314992PF00567
DomainSpectrin_alpha_SH3

SPTA1 SPTAN1

2.79e-0315992IPR013315
DomainTPR_8

RPAP3 TTC21A TTC21B

2.79e-0353993PF13181
DomainDH_1

ECT2 ARHGEF15 ARHGEF40

4.56e-0363993PS00741
DomainCH

SYNE1 SYNE2 MACF1

4.97e-0365993SM00033
PathwayREACTOME_EICOSANOIDS

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.86e-0912755M27129
PathwayREACTOME_EICOSANOIDS

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.86e-0912755MM14845
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

7.18e-0914755MM15842
PathwayREACTOME_FATTY_ACIDS

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.07e-0815755M27126
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.02e-0818755MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.02e-0818755MM14841
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.82e-0725755MM14858
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

7.87e-0733755MM15918
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

7.87e-0733755MM15963
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F8 CYP4F2 CYP4F3 CYP4F11

4.13e-0621754M27137
PathwayWP_TRYPTOPHAN_METABOLISM

CYP4F8 CYP4F2 TDO2 CYP4F12 CYP4F11

5.33e-0648755MM15902
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.76e-0561755MM14861
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11 MTARC1

1.86e-05104756M738
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.90e-0562755M39653
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11 MTARC1

1.96e-05105756MM14842
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.22e-0564755M5650
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP4F2 CYP4F12 CYP4F11

2.31e-0511753MM14863
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.58e-0566755MM14839
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F2 CYP4F3 CYP4F11

3.07e-0512753M27128
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP4F8 CYP4F2 BPNT1 CYP4F3 CYP4F12 CYP4F11 MTARC1

1.61e-04219757MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP4F8 CYP4F2 BPNT1 CYP4F3 CYP4F12 CYP4F11 MTARC1

1.65e-04220757M10320
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F8 CYP4F2 CYP4F3 CYP4F11

2.70e-0459754M27140
PathwayWP_GASTRIC_CANCER_NETWORK_1

NUP107 ECT2 TOP2A

4.31e-0428753M39347
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY

CYP4F2 CYP4F12

9.81e-049752M39819
PathwayREACTOME_RHOA_GTPASE_CYCLE

ECT2 ARHGEF15 ARHGEF40 DLC1 ARAP2

1.17e-03149755M41805
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SPTA1 SPTAN1

1.22e-0310752MM15112
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.01e-1269959068972
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F8 CYP4F2 CYP4F12 CYP4F11

6.18e-11499422665481
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F8 CYP4F2 CYP4F12 CYP4F11

6.18e-11499411185557
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3 CYP4F12 CYP4F11

6.18e-11499418065749
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F8 CYP4F2 CYP4F12 CYP4F11

3.08e-10599422969154
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F8 CYP4F2 CYP4F12 CYP4F11

3.08e-10599421466787
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

CYP4F8 CYP4F2 CYP4F12 CYP4F11

2.15e-09799422160543
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SYNE1 TOGARAM1 ARHGEF15 MYOF ESYT2 MESD SYNE2 MACF1 BAIAP3

1.77e-0822599912168954
Pubmed

Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues.

STXBP1 STXBP2 STXBP3

2.24e-0839937890715
Pubmed

Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links.

ERCC4 SPTA1 SPTAN1

8.93e-08499312571280
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

GPHN SFMBT1 NUP107 PARG CKAP5 PRC1 CBFA2T3 ECT2 TTLL7 LIG3 ESYT2 NOP14 MAPK9 TOP2A

1.50e-07857991425609649
Pubmed

Different Munc18 proteins mediate baseline and stimulated airway mucin secretion.

STXBP1 STXBP2 STXBP3

2.23e-07599330721150
Pubmed

Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells.

STXBP1 STXBP2 STXBP3

2.23e-07599329599294
Pubmed

Cellular munc18c levels can modulate glucose transport rate and GLUT4 translocation in 3T3L1 cells.

STXBP1 STXBP2 STXBP3

7.77e-07799312297296
Pubmed

A role for Sec1/Munc18 proteins in platelet exocytosis.

STXBP1 STXBP2 STXBP3

7.77e-07799312773094
Pubmed

MUNC18-1 gene abnormalities are involved in neurodevelopmental disorders through defective cortical architecture during brain development.

STXBP1 STXBP2 STXBP3

7.77e-07799329191246
Pubmed

DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC.

NUP107 BAZ1B PRC1 NOP14 ARID2 TOP2A

1.16e-0611899637105989
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NUP107 RPAP3 TAF1C SPTAN1 CKAP5 BAZ1B VPS16 ECT2 LIG3 ARHGEF40 NOP14 PSME4 MACF1 ATIC EXOC2 TOP2A

1.36e-061353991629467282
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RALGAPA1 KRT14 NUP107 RPAP3 SPTAN1 PCF11 ESYT2 NOP14 AKAP9 STXBP3 SUPT5H SYNE2 USP12 MAPK9

1.66e-061049991427880917
Pubmed

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.76e-067099515128046
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

NUP107 SYNE1 SPTAN1 SPTLC1 CKAP5 BAZ1B PRC1 SYAP1 LIG3 STXBP3 CLCA2 SUPT5H PPA2 ATIC MYO18B TOP2A

2.65e-061425991630948266
Pubmed

Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.

CYP4F8 ERCC4 CYP4F2 CYP4F12 CYP4F11

2.66e-067699522323595
Pubmed

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.

GPHN AKAP9 SYNE2 MACF1

3.80e-063799427565344
Pubmed

Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.

CYP4F8 CYP4F2 CYP4F12 CYP4F11

7.68e-064499412745259
Pubmed

Calsequestrin Deletion Facilitates Hippocampal Synaptic Plasticity and Spatial Learning in Post-Natal Development.

CASQ1 CASQ2

8.02e-06299232751833
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

8.02e-06299222768332
Pubmed

Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

CYP4F2 CYP4F11

8.02e-06299224138531
Pubmed

Expression of CYP4F2 in human liver and kidney: assessment using targeted peptide antibodies.

CYP4F2 CYP4F12

8.02e-06299218662666
Pubmed

Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary entry of membrane protein, Hedgehog signaling, and embryogenesis.

TTC21A TTC21B

8.02e-06299232167205
Pubmed

Bi-Allelic Mutations in STXBP2 Reveal a Complementary Role for STXBP1 in Cytotoxic Lymphocyte Killing.

STXBP1 STXBP2

8.02e-06299229599780
Pubmed

Crucial role of the hydrophobic pocket region of Munc18 protein in mast cell degranulation.

STXBP1 STXBP2

8.02e-06299223487749
Pubmed

Expression and physiological function of CYP4F subfamily in human eosinophils.

CYP4F3 CYP4F12

8.02e-06299217980168
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

8.02e-06299211792814
Pubmed

Cloning of the genes encoding mouse cardiac and skeletal calsequestrins: expression pattern during embryogenesis.

CASQ1 CASQ2

8.02e-0629929795116
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

8.02e-0629928026587
Pubmed

Differential effect of calsequestrin ablation on structure and function of fast and slow skeletal muscle fibers.

CASQ1 CASQ2

8.02e-06299221941434
Pubmed

Calsequestrin depolymerizes when calcium is depleted in the sarcoplasmic reticulum of working muscle.

CASQ1 CASQ2

8.02e-06299228069951
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

8.02e-06299224931616
Pubmed

Mitochondrial Ca2+-handling in fast skeletal muscle fibers from wild type and calsequestrin-null mice.

CASQ1 CASQ2

8.02e-06299224098358
Pubmed

Knocking down type 2 but not type 1 calsequestrin reduces calcium sequestration and release in C2C12 skeletal muscle myotubes.

CASQ1 CASQ2

8.02e-06299216595676
Pubmed

Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8.

CYP4F8 CYP4F12

8.02e-06299216112640
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE1 SYNE2

8.02e-06299217267447
Pubmed

Endogenous and maximal sarcoplasmic reticulum calcium content and calsequestrin expression in type I and type II human skeletal muscle fibres.

CASQ1 CASQ2

8.02e-06299224127619
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE1 SYNE2

8.02e-06299224718612
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE1 SYNE2

8.02e-06299224586179
Pubmed

Paradoxical buffering of calcium by calsequestrin demonstrated for the calcium store of skeletal muscle.

CASQ1 CASQ2

8.02e-06299220713548
Pubmed

The N-peptide-binding mode is critical to Munc18-1 function in synaptic exocytosis.

STXBP1 STXBP2

8.02e-06299230275014
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE1 SYNE2

8.02e-06299217761684
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE1 SYNE2

8.02e-06299231578382
Pubmed

Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

CYP4F3 CYP4F11

8.02e-06299215364545
Pubmed

Genetic Interaction of Thm2 and Thm1 Shapes Postnatal Craniofacial Bone.

TTC21A TTC21B

8.02e-06299235645293
Pubmed

αII-spectrin regulates invadosome stability and extracellular matrix degradation.

SPTA1 SPTAN1

8.02e-06299225830635
Pubmed

Munc18-1 and Munc18-2 proteins modulate beta-cell Ca2+ sensitivity and kinetics of insulin exocytosis differently.

STXBP1 STXBP2

8.02e-06299221690086
Pubmed

Munc18-syntaxin complexes and exocytosis in human platelets.

STXBP2 STXBP3

8.02e-06299212649283
Pubmed

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.

CYP4F8 CYP4F2 CYP4F12 CYP4F11

9.19e-064699425209997
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

GPHN NUP107 SPTAN1 BPNT1 MYOF STXBP2 STXBP3 PPA2 ATIC TOP2A

9.43e-06607991039147351
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

GPHN NUP107 RPAP3 PARG CKAP5 BAZ1B SYAP1 LIG3 ARID2 MACF1 ATIC TOP2A

1.42e-05934991233916271
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

RALGAPA1 NUP107 RPAP3 SYNE1 SPTAN1 SPTLC1 BAZ1B PCF11 ESYT2 NOP14 AKAP9 STXBP3 SYNE2 PPA2 MACF1

2.00e-051487991533957083
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

RALGAPA1 KRT14 RPAP3 SPTAN1 ECT2 PPA2 MACF1 MYO18B TOP2A

2.39e-0553899928524877
Pubmed

Accelerated activation of SOCE current in myotubes from two mouse models of anesthetic- and heat-induced sudden death.

CASQ1 CASQ2

2.40e-05399224143248
Pubmed

Identification of four different forms of syntaxin 3.

STXBP1 STXBP2

2.40e-0539927598732
Pubmed

Role of the JP45-Calsequestrin Complex on Calcium Entry in Slow Twitch Skeletal Muscles.

CASQ1 CASQ2

2.40e-05399227189940
Pubmed

Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.

CYP4F2 CYP4F3

2.40e-05399215145985
Pubmed

Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.

SYNE1 SYNE2

2.40e-05399210878022
Pubmed

The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.

SYNE1 SYNE2

2.40e-05399216079285
Pubmed

The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.

SYNE1 SYNE2

2.40e-05399212408964
Pubmed

Doc2b serves as a scaffolding platform for concurrent binding of multiple Munc18 isoforms in pancreatic islet β-cells.

STXBP1 STXBP3

2.40e-05399225190515
Pubmed

Ankyrin-independent membrane protein-binding sites for brain and erythrocyte spectrin.

SPTA1 SPTAN1

2.40e-0539922971657
Pubmed

Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.

SYNE1 SYNE2

2.40e-05399217462627
Pubmed

Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.

SYNE1 SYNE2

2.40e-05399233472039
Pubmed

Thm2 interacts with paralog, Thm1, and sensitizes to Hedgehog signaling in postnatal skeletogenesis.

TTC21A TTC21B

2.40e-05399233683377
Pubmed

Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.

SYNE1 SYNE2

2.40e-05399225516977
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

VPS16 ANKRD13A PSME4 SUPT5H ARID2 TOP2A

3.34e-0521299633853758
Pubmed

CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1.

SPTLC1 MYOF PLAUR ATIC

3.44e-056499436369321
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

GPHN RALGAPA1 SPTAN1 CKAP5 ECT2 ESYT2 DLC1 AKAP9 SYNE2 MACF1 ARAP2

3.49e-05861991136931259
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

KRT14 NUP107 SYNE1 CKAP5 BAZ1B LIG3 STXBP2 SUPT5H SYNE2 MACF1 ATIC TOP2A

3.50e-051024991224711643
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

BAZ1B MESD STXBP1 PSME4 SYNE2 MACF1 ATIC

3.93e-0532299726514267
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

SPTAN1 CKAP5 BAZ1B MYOF NFE2L1 MACF1 TOP2A

4.76e-0533299737433992
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

NUP107 SPTAN1 CKAP5 PRC1 SUPT5H ARID2 TOP2A

4.76e-0533299732786267
Pubmed

Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4.

STXBP1 STXBP3

4.79e-05499220053958
Pubmed

A murine neural-specific homolog corrects cholinergic defects in Caenorhabditis elegans unc-18 mutants.

STXBP1 STXBP3

4.79e-0549928824310
Pubmed

Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton.

SPTA1 SPTAN1

4.79e-0549929593709
Pubmed

SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.

SYNE1 SYNE2

4.79e-05499216648470
Pubmed

Human alpha spectrin II and the Fanconi anemia proteins FANCA and FANCC interact to form a nuclear complex.

SPTA1 SPTAN1

4.79e-05499210551855
Pubmed

LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.

SYNE1 SYNE2

4.79e-05499223071752
Pubmed

A novel isoform of syntaxin-binding protein homologous to yeast Sec1 expressed ubiquitously in mammalian cells.

STXBP1 STXBP2

4.79e-0549927890599
Pubmed

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.

SPTA1 SPTAN1

4.79e-05499221566095
Pubmed

Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin.

SPTA1 SPTAN1

4.79e-0549923862089
Pubmed

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.

SYNE1 SYNE2

4.79e-05499220108321
Pubmed

Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells.

SYNE1 AKAP9

4.79e-05499228966089
Pubmed

Mapping of a spectrin-binding domain of human erythrocyte membrane protein 4.2.

SPTA1 SPTAN1

4.79e-05499212049649
Pubmed

Conditional knockout of TOG results in CNS hypomyelination.

CKAP5 TOGARAM1

4.79e-05499228063167
Pubmed

Disruption of spectrin-like cytoskeleton in differentiating keratinocytes by PKCδ activation is associated with phosphorylated adducin.

SPTA1 SPTAN1

4.79e-05499222163289
Pubmed

Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.

SYNE1 SYNE2

4.79e-05499219596800
Pubmed

Spectrin alpha II and beta II isoforms interact with high affinity at the tetramerization site.

SPTA1 SPTAN1

4.79e-05499212820899
Pubmed

Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.

SYNE1 SYNE2

4.79e-05499228716842
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

SPTAN1 PARG CKAP5 BAZ1B SYAP1 PCF11 MYOF ESYT2 EXOC2 TOP2A

7.37e-05774991015302935
Pubmed

TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.

KRT14 NUP107 LIG3 ESYT2 TOP2A

7.67e-0515299528192407
Pubmed

Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4.

STXBP1 STXBP2

7.98e-0559929045631
Pubmed

Plectin and IFAP-300K are homologous proteins binding to microtubule-associated proteins 1 and 2 and to the 240-kilodalton subunit of spectrin.

SPTA1 SPTAN1

7.98e-0559923027087
Cytoband19p13.1

CYP4F8 CYP4F12 CYP4F11

1.57e-044899319p13.1
GeneFamilyCytochrome P450 family 4

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.23e-07366851003
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

8.32e-0546821252
GeneFamilyEF-hand domain containing|Spectrins

SPTA1 SPTAN1

2.89e-0476821113
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ECT2 ARHGEF15 ARHGEF40

1.97e-0366683722
GeneFamilyProtein disulfide isomerases

CASQ1 CASQ2

2.79e-0321682692
GeneFamilyIntraflagellar transport proteins|Tetratricopeptide repeat domain containing

TTC21A TTC21B

3.65e-0324682615
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

CBFA2T3 AKAP9

5.30e-0329682396
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SFMBT1 PARG CKAP5 BAZ1B TOGARAM1 PCF11 MYOF DLC1 AKAP9 STXBP3 PSME4 SYNE2 USP12 MACF1 PLAUR TOP2A ARAP2

2.10e-088569917M4500
CoexpressionSAENZ_DETOX_PATHWAY_AND_CARCINOGENESIS_DN

CYP4F8 CYP4F2 CYP4F12 CYP4F11

8.86e-0720994MM1104
CoexpressionZENG_GU_POST_ICB_METAGENE_39

CYP4F8 CYP4F2 FAR2 CYP4F12 BAIAP3 CYP4F11 ABCG8

1.27e-05204997MM17090
CoexpressionCUI_TCF21_TARGETS_2_DN

SFMBT1 CBFA2T3 PGGT1B TRIM5 ARHGEF15 TTLL7 MYOF LATS2 STXBP3 ABCA5 USP12 MACF1 ARAP2

1.99e-058549913M1533
CoexpressionCUI_TCF21_TARGETS_2_DN

SFMBT1 CBFA2T3 PGGT1B TRIM5 ARHGEF15 TTLL7 MYOF LATS2 STXBP3 ABCA5 USP12 MACF1 ARAP2

2.98e-058889913MM1018
CoexpressionGSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_DN

NUP107 POGK PRC1 BPNT1 TOP2A ARAP2

3.93e-05165996M8121
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000

RALGAPA1 SFMBT1 ERCC4 BAZ1B CCDC141 LIG3 LATS2 AKAP9 ARID2 USP12

9.23e-063799710gudmap_developingKidney_e15.5_1000_k3
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000

RALGAPA1 ERCC4 BAZ1B CCDC141 LIG3 AKAP9 ARID2 USP12

2.63e-05261978gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_500

RALGAPA1 SFMBT1 ERCC4 BAZ1B LATS2 AKAP9 ARID2

3.84e-05201977gudmap_developingKidney_e15.5_500_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000

RALGAPA1 SFMBT1 ERCC4 BAZ1B TRIM5 LIG3 DLC1 AKAP9 ATIC

6.76e-05385979gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000

CYP4F8 ZNF157 TRIM5 PCF11 METTL24 STXBP2 AKAP9 STXBP3 CLCA2 ZNF277 CYP4F3 MAPK9 ARAP2

7.39e-058049713gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_1000
CoexpressionAtlasDevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#5_top-relative-expression-ranked_1000

RALGAPA1 ERCC4 BAZ1B TRIM5 LIG3 LATS2 ARID2

8.04e-05226977gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000_k5
CoexpressionAtlasB cells, B.Pl.AA4-.BM, CD138+ AA4.1- CD43+, Bone marrow, avg-2

SYNE1 PRC1 ECT2 FAR2 SYNE2 PLAUR CYP4F3 MMP8 TOP2A

8.07e-05394979GSM777030_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_200

CASQ2 MYOF DLC1 CLCA2

1.54e-0459974gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_200
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000

RALGAPA1 SFMBT1 ERCC4 BAZ1B LIG3 AKAP9 ARID2 USP12

1.64e-04339978gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SYNE1 AKAP9 SYNE2 MACF1 ABCG8 TOP2A ARAP2

2.21e-08135997ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SYNE1 SPTA1 FAR2 CYP4F3 MMP8 TOP2A MTARC1

2.47e-07192997072281344d58e85c9a290750b488d0c101f75d54
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RALGAPA1 SYNE1 AKAP9 ABCA5 SYNE2 MACF1 ARAP2

3.14e-07199997f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RALGAPA1 SYNE1 AKAP9 SYNE2 MACF1 ARAP2

2.31e-061719962e9a20f8980b78325c52065a9c14ab3656267c05
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 BAZ1B TTLL7 AKAP9 SYNE2 ARAP2

2.91e-0617899601dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

RALGAPA1 SPTAN1 ARID2 SYNE2 MACF1 ARAP2

3.21e-06181996f2315414e714ac86211546a935660c4be6e85f1b
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

PRC1 ECT2 STXBP2 ZFYVE26 TOP2A MTARC1

3.87e-061879963c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SYNE1 STXBP2 SYNE2 PLAUR CYP4F3 MMP8

5.37e-0619899682f6ac18c3a6487f03579b5c247844f1c115c2be
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SYNE1 STXBP2 SYNE2 PLAUR CYP4F3 MMP8

5.37e-06198996f870e398e996c1f28c8462d87b18f71b20c71011
ToppCellCOVID-19_Severe-immature_Neutrophil|COVID-19_Severe / Disease condition and Cell class

SYNE1 FAR2 SYNE2 CYP4F3 MMP8 TOP2A

5.53e-06199996f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCellCOVID-19_Severe-immature_Neutrophil-|COVID-19_Severe / Disease condition and Cell class

SYNE1 FAR2 SYNE2 CYP4F3 MMP8 TOP2A

5.53e-0619999642ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SPTAN1 ARHGEF15 DLC1 STXBP1 SYNE2 MACF1

5.69e-0620099672ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SPTAN1 ARHGEF15 DLC1 STXBP1 SYNE2 MACF1

5.69e-06200996dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

RNASEH2A CKAP5 PRC1 ECT2 MMP8 TOP2A

5.69e-06200996118321ac443feb42aee171baccfc4610f00a8822
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

SPTAN1 ARHGEF15 DLC1 STXBP1 SYNE2 MACF1

5.69e-06200996edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SPTAN1 ARHGEF15 DLC1 STXBP1 SYNE2 MACF1

5.69e-062009965c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

SPTAN1 ARHGEF15 DLC1 STXBP1 SYNE2 MACF1

5.69e-0620099681e76508c9050d533853d5fd2f3097b27613d836
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SPTAN1 ARHGEF15 DLC1 STXBP1 SYNE2 MACF1

5.69e-06200996a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellSigmoid-(1)_T_cell-(18)_cycling_gd_T|Sigmoid / shred on region, Cell_type, and subtype

PRC1 ECT2 MYOF ZFYVE26 TOP2A ARAP2

5.69e-062009966e367abd1a4b87e20eb9095b8337723163e8bbae
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

SPTAN1 ARHGEF15 DLC1 STXBP1 SYNE2 MACF1

5.69e-062009964bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCellSigmoid-T_cell-cycling_gd_T|Sigmoid / Region, Cell class and subclass

PRC1 ECT2 MYOF ZFYVE26 TOP2A ARAP2

5.69e-062009969769185abae084ffac36420c749625e679b70ca8
ToppCellEndothelial-Endothelial-H_(cycle)|Endothelial / shred on cell class and cell subclass (v4)

CKAP5 PRC1 ECT2 PCF11 TOP2A

1.43e-05138995a1f41a5a9da40adcc343722baef78c603599c3f0
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASQ2 PRC1 ECT2 MMP8 TOP2A

1.88e-0514699545d7cb73776e60d22f335a651845e21e16948fcc
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ERCC4 TDO2 KATNAL1 ECT2 ZFYVE26

3.58e-05167995a48349f189f6a8d563744b0a294c3974f3a18f50
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CKAP5 PRC1 ECT2 WDR87 TOP2A

3.79e-05169995563c267edaade0e5df192ad953801ef9768d4270
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PSD2 PRC1 ECT2 ARHGEF40 TOP2A

4.12e-05172995c06ca5d075937747952ed915c9db39a9f62072f9
ToppCellHealthy_Control-Myeloid-Mast|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PSD2 CBFA2T3 TTLL7 ARHGEF40 CYP4F11

4.47e-05175995ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCellHealthy_Control-Myeloid-Mast-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PSD2 CBFA2T3 TTLL7 ARHGEF40 CYP4F11

4.47e-05175995eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 PRC1 FAR2 SYNE2 TOP2A

5.25e-05181995566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 PRC1 FAR2 SYNE2 TOP2A

5.25e-05181995db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 CKAP5 PRC1 SYNE2 TOP2A

5.39e-051829959025178ede571e3808d4657ad4892152f336c9b4
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE1 CKAP5 PRC1 SYNE2 TOP2A

5.39e-05182995c075756cd4bb484ede1be2bcdb9eac60eab0573a
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNASEH2A PRC1 ECT2 MMP8 TOP2A

5.68e-05184995a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNASEH2A PRC1 ECT2 MMP8 TOP2A

5.68e-05184995081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

RNASEH2A PRC1 ECT2 MMP8 TOP2A

5.68e-0518499545f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellIIF-Lymphocyte-T_NK-T_NK_proliferative|IIF / Disease, Lineage and Cell Type

RNASEH2A PRC1 ECT2 CYP4F11 TOP2A

5.68e-05184995ab8b45ce40e8c5f66e5c23332a591b4f9cba4ce1
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNASEH2A PRC1 ECT2 MMP8 TOP2A

5.68e-0518499584c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNASEH2A PRC1 ECT2 MMP8 TOP2A

5.68e-05184995d31d4116d1d196633784863781fa45673607a421
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

RNASEH2A PRC1 ECT2 MMP8 TOP2A

5.68e-05184995c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

RNASEH2A PRC1 ECT2 MMP8 TOP2A

5.68e-051849952fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ1B PRC1 CLCA2 SYNE2 TOP2A

5.98e-0518699515ab6666748a641226e42e6ca6eeaf186a501c95
ToppCelldroplet-Tongue-nan-24m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT14 TTLL7 DLC1 SYNE2 ARAP2

5.98e-051869952913b5fd0617d024d600ba7015ec7b1961dade83
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ1B PRC1 CLCA2 SYNE2 TOP2A

5.98e-051869954ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

RALGAPA1 ARID2 SYNE2 MACF1 ARAP2

6.29e-05188995ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SYNE1 SPTA1 CYP4F3 MMP8 TOP2A

6.29e-05188995557a0ac069a6ff4e687cac032f64170b9b247165
ToppCellT_cells-GZMK+_CD8+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CCDC141 SYNE2 MACF1 EXOC2 ARAP2

6.44e-05189995e2ca075aedf7c370ab4ede6272254ffd06cbcdec
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPTAN1 ESYT2 SYNE2 MACF1 ARAP2

6.61e-0519099591ba66d4b56c59523485b17738e93f14bb00afa4
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKAP5 PRC1 ECT2 METTL24 TOP2A

6.61e-05190995b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 FAR2 CYP4F3 MMP8 TOP2A

6.77e-051919956c1283d51a845cff67ed5e500f7e944165297b53
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 SPTAN1 METTL24 SYNE2 ARAP2

6.77e-051919954a29b7d5cd10e9077699d3aa76e3db6c4d5a0cf6
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RALGAPA1 ESYT2 SYNE2 MACF1 ARAP2

6.94e-0519299547646d7e4990be85072987f92bf18d52f8da752e
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 AKAP9 SYNE2 MACF1 ARAP2

7.11e-051939959337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCelldroplet-Tongue-nan-3m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT14 TTLL7 DLC1 SYNE2 ARAP2

7.11e-05193995a7002acf3be76b2cc6fc9364176f6b0d3bd27d9c
ToppCellPSB-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RNASEH2A PRC1 ECT2 EPS8L3 TOP2A

7.11e-05193995b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

SPTA1 CKAP5 PRC1 ECT2 TOP2A

7.47e-05195995764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-neutrophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SYNE1 STXBP2 PLAUR MMP8 MTARC1

7.47e-05195995fb3dc2c8fd125f23d0c3aa211520778aac8d6dda
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 CCDC141 DLC1 STXBP1 MTARC1

7.47e-0519599537aa6e4123d37de4de42ca68d3020f2a7686ce02
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RNASEH2A CKAP5 PRC1 ECT2 TOP2A

7.65e-051969959591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNASEH2A CKAP5 PRC1 ECT2 TOP2A

7.84e-0519799541bdea47b9b1f6415a866a515d1535ea942fdede
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 AKAP9 SYNE2 MACF1 ARAP2

7.84e-0519799557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CKAP5 PRC1 ECT2 PPA2 TOP2A

7.84e-051979956de02b02fcdfcab1c1b0f4a4c75677410bc55688
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT14 PRC1 MYOF CLCA2 TOP2A

7.84e-051979952430f31d9312338e0ca23bfc6bdb0365340860fd
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

STXBP2 PLAUR CYP4F3 MMP8 MTARC1

8.03e-05198995df546a9afc0e15398f33c1b511c7281771f9aea0
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-neutrophil-myelocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SYNE1 STXBP2 FAR2 SYNE2 MMP8

8.03e-051989953bc05b8d97a7219af40db7a11aa271f02e74fca5
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NUP107 RNASEH2A PRC1 ECT2 TOP2A

8.03e-0519899536897e17de2e22ee6b23920ee6e60931903f3e5c
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SYNE1 STXBP2 SYNE2 PLAUR MMP8

8.22e-051999955919933c4b842b98fc98685dc8c72c8dd32c6ea3
ToppCell18-Airway-Mesenchymal-Mesenchyme_RSPO2+|Airway / Age, Tissue, Lineage and Cell class

TDO2 PRC1 ECT2 MACF1 TOP2A

8.22e-051999957ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCellCOVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil|COVID-19_Mild / Disease, condition lineage and cell class

PRC1 FAR2 CYP4F3 MMP8 TOP2A

8.22e-05199995e222b90caf45904d8f763574e7b6aac13333df92
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

SYNE1 ESYT2 SYNE2 MACF1 ARAP2

8.22e-05199995e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYNE1 PRC1 ECT2 SYNE2 TOP2A

8.22e-05199995101f78fe6dd1bf9e2e4dd5ad8a970312b3540927
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 PRC1 ECT2 SYNE2 TOP2A

8.22e-05199995e0fcec796afe75e42467ca86355b9fc5aa9ae0a1
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SYNE1 STXBP2 CYP4F3 MMP8 MTARC1

8.22e-05199995b7af2b4fe6866cc8c78cf0f78390aab1b1b389ba
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

SYNE1 ESYT2 SYNE2 MACF1 ARAP2

8.22e-051999955f914962e2572b0c6372465b81b7496fa663d93c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

RNASEH2A CKAP5 PRC1 ECT2 TOP2A

8.22e-05199995d8f904f531bfe091b7d8caaa147ea4a03d627995
ToppCellTCGA-Cervix-Primary_Tumor|TCGA-Cervix / Sample_Type by Project: Shred V9

RNASEH2A PRC1 ECT2 STXBP2 TOP2A

8.22e-05199995ef6fde26af2ca9e6cde198ac0e14e03d9ab398f8
ToppCellTCGA-Stomach-Primary_Tumor|TCGA-Stomach / Sample_Type by Project: Shred V9

CKAP5 PRC1 ECT2 ATIC TOP2A

8.22e-0519999538f1f612b29feb868322999ceeda78e52447ec4f
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SYNE1 STXBP2 SYNE2 PLAUR MMP8

8.22e-05199995caf2e050b21e7a16ce4e51b3f135debd06810231
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T|COVID-19_Mild / Disease, condition lineage and cell class

SPTAN1 CCDC141 SYNE2 MACF1 ARAP2

8.22e-05199995f307d4887b28cf60a591439e278fd668409cb104
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma|TCGA-Stomach / Sample_Type by Project: Shred V9

CKAP5 PRC1 ECT2 ATIC TOP2A

8.22e-05199995b10698aee2e6c17bc559eb4f723024141f914b90
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE1 TDO2 MYOF AKAP9 MACF1

8.41e-052009959b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RALGAPA1 SPTAN1 FAR2 NFE2L1 SYNE2

8.41e-052009957eb366b2c5394af7c77650bde6261e7dac67154e
ToppCellCOVID-19-COVID-19_Severe-Myeloid-immature_Neutrophil|COVID-19_Severe / Disease, condition lineage and cell class

SYNE1 FAR2 CYP4F3 MMP8 TOP2A

8.41e-05200995cbe667eda1af222467df8bfa157aa22df488f133
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

CKAP5 PRC1 ECT2 SYNE2 TOP2A

8.41e-052009950d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell(5)_Epi_dividing|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

KRT14 RNASEH2A PRC1 ECT2 TOP2A

8.41e-05200995948c55aa1c25f8a69b1bd3ef53fd32aa222f592c
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

SPTAN1 ARHGEF15 DLC1 STXBP1 MACF1

8.41e-05200995eb94a5111ef0e903ee5be9f7efe571b4e6d5fce1
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells|2m / Sample Type, Dataset, Time_group, and Cell type.

CKAP5 PRC1 ECT2 SYNE2 TOP2A

8.41e-052009950675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell(5)_Epithelial_cells-(5)_Epi_dividing|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

KRT14 RNASEH2A PRC1 ECT2 TOP2A

8.41e-05200995b46b2064362efc64edf19ab2b21bc89047c9d943
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

SPTAN1 ARHGEF15 DLC1 STXBP1 MACF1

8.41e-052009953b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCellSigmoid-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

PRC1 ECT2 MYOF ZFYVE26 TOP2A

8.41e-052009954e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCellmild-gd_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 AKAP9 SYNE2 MACF1 ARAP2

8.41e-05200995109f673a4967ffa52270a0b4f818b3461288db44
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

SYNE1 ESYT2 SYNE2 MACF1 ARAP2

8.41e-05200995f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)|Thalamus / BrainAtlas - Mouse McCarroll V32

ECT2 METTL24 TOP2A TDRD12

9.92e-0510899463d45cc3ee149a7baf255b70409f8ea54c56157b
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P3-Tnr|Thalamus / BrainAtlas - Mouse McCarroll V32

ECT2 METTL24 TOP2A TDRD12

9.92e-05108994d57eeda825b6e0e64bae185896ae7eea6a2a50e9
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-|Thalamus / BrainAtlas - Mouse McCarroll V32

ECT2 METTL24 TOP2A TDRD12

9.92e-05108994c2aa6bf8554bfb6b0f9c5f6658601c6cf7c8bdbc
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P3|Thalamus / BrainAtlas - Mouse McCarroll V32

ECT2 METTL24 TOP2A TDRD12

9.92e-05108994db8472616886c6195f8c27c00f00133a9c10691d
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

SYNE1 AKAP9 SYNE2 MACF1

1.54e-0412199419333a660800b583fa27b495c1f7828e6636a257
ToppCellCaecum-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

STXBP2 PLAUR

1.71e-04999282af19cc3e7c97300a5cbed1bbcbbc9226c8db01
ToppCellEndothelial-H_(cycle)|World / shred on cell class and cell subclass (v4)

CKAP5 PRC1 ECT2 TOP2A

2.21e-041339948e3005114761feee028c496cc739e607b35d7831
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

SYNE1 TAF1C PCF11 FAR2

2.34e-04135994ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-7|TCGA-Stomach / Sample_Type by Project: Shred V9

CASQ1 CASQ2 TTLL7 METTL24

2.34e-04135994451e90c154e26ae4f72269d6765e7ef51d67313a
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

SYNE1 AKAP9 SYNE2 MACF1

2.37e-0449674GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

BAZ1B NOP14 SYNE2 MACF1

2.56e-0450674GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Drugdichloran

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

9.29e-0741995CID000007430
Drugebastine

CYP4F8 CYP4F2 CYP4F3 CYP4F12

3.97e-0625994CID000003191
Drug18-HETE

CYP4F8 CYP4F2 CYP4F12

9.36e-0610993CID006442778
Drugpropoxyphene

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.10e-0567995CID000010100
Drug8-MOP

CYP4F8 ERCC4 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.29e-05118996CID000004114
Drugcarteolol

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

1.56e-0572995CID000002583
Drugthiophenone

SYNE1 TDO2

1.87e-052992CID009548690
Drugazo analog I

CYP4F8 CYP4F3 CYP4F12

2.21e-0513993CID006438575
DrugAC1O5PIQ

CYP4F8 CYP4F2 CYP4F3 CYP4F12

2.46e-0539994CID006438348
Drugtrimipramine

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

2.61e-0580995CID000005584
Drugplakin

SYNE1 SPTA1 SPTAN1 SYNE2 MACF1

2.94e-0582995CID000018752
Drugdiosmetin

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

3.50e-0585995CID005281612
Drugmephenytoin

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

4.13e-0588995CID000004060
Drugtienilic acid

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.39e-0593995CID000038409
Druglansoprazole

CYP4F8 CYP4F2 CYP4F3 CYP4F12 CYP4F11

5.39e-0593995CID000003883
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

TDRD15 SYNE2 MACF1 PLAUR ABCG8 MTARC1

1.05e-05150976EFO_0004611, EFO_0020947
Diseasenon-high density lipoprotein cholesterol measurement

TDRD15 SPTA1 TRIM5 ARHGEF15 ESYT2 DLC1 FAR2 SYNE2 CYP4F12 ABCG8 MTARC1

2.29e-057139711EFO_0005689
DiseaseMalignant neoplasm of breast

KRT14 SYNE1 SPTAN1 SPTLC1 PRC1 ECT2 AKAP9 CLCA2 ZNF277 SYNE2 MACF1 ZFYVE26 TOP2A

5.03e-0510749713C0006142
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

TDRD15 TRIM5 SYNE2 MACF1 PLAUR ABCG8 MTARC1

5.08e-05291977EFO_0008317, EFO_0020946
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

TDRD15 SYNE2 MACF1 ABCG8 MTARC1

5.09e-05121975EFO_0008595, EFO_0020943
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

6.39e-054972cv:CN293514
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

SYNE2 MACF1 PLAUR ABCG8 MTARC1

6.41e-05127975EFO_0008595, EFO_0020947
Diseasefree cholesterol measurement, low density lipoprotein cholesterol measurement

TDRD15 BAZ1B PLAUR ABCG8 MTARC1

9.17e-05137975EFO_0004611, EFO_0008591
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

TDRD15 TRIM5 SYNE2 MACF1 ABCG8 MTARC1

9.47e-05222976EFO_0008317, EFO_0020943
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

TDRD15 TRIM5 MACF1 PLAUR ABCG8 MTARC1

1.02e-04225976EFO_0008317, EFO_0020947
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

1.06e-045972C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

1.06e-045972C0410190
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

TDRD15 SYNE2 MACF1 ABCG8 MTARC1

1.16e-04144975EFO_0004611, EFO_0020943
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

TDRD15 TRIM5 MACF1 PLAUR ABCG8 MTARC1

1.42e-04239976EFO_0008317, EFO_0020945
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

1.59e-046972cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

1.59e-046972C0410189
Diseaseintermediate density lipoprotein measurement

TDRD15 BAZ1B ABCG8 MTARC1

1.98e-0487974EFO_0008595
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

2.22e-047972C0751337
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

TDRD15 TRIM5 SYNE2 MACF1 ABCG8 MTARC1

2.43e-04264976EFO_0008317, EFO_0020944
Diseasecholesteryl ester measurement, intermediate density lipoprotein measurement

TDRD15 BAZ1B ABCG8 MTARC1

2.67e-0494974EFO_0008595, EFO_0010351
Diseaselipid measurement, intermediate density lipoprotein measurement

TDRD15 BAZ1B ABCG8 MTARC1

2.89e-0496974EFO_0004529, EFO_0008595
Diseasecholesterol in very small VLDL measurement

TDRD15 TRIM5 ABCG8

3.11e-0440973EFO_0022231
Diseasetotal cholesterol measurement, intermediate density lipoprotein measurement

TDRD15 BAZ1B ABCG8 MTARC1

3.25e-0499974EFO_0004574, EFO_0008595
Diseasephospholipid measurement, intermediate density lipoprotein measurement

TDRD15 TRIM5 ABCG8 MTARC1

3.25e-0499974EFO_0004639, EFO_0008595
Diseasenephronophthisis (implicated_via_orthology)

TTC21A TTC21B

3.79e-049972DOID:12712 (implicated_via_orthology)
Diseasehexadecenedioate (C16:1-DC) measurement

CYP4F2 CYP4F11

3.79e-049972EFO_0800562
Diseasefree cholesterol measurement, intermediate density lipoprotein measurement

TDRD15 BAZ1B ABCG8 MTARC1

3.92e-04104974EFO_0008591, EFO_0008595
Diseasefree cholesterol in very small VLDL measurement

TDRD15 TRIM5 ABCG8

5.03e-0447973EFO_0022275
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

TDRD15 SYNE2 MACF1 PLAUR MTARC1

5.29e-04200975EFO_0004611, EFO_0020945
Diseaseoptic disc size measurement

ZNF157 RPAP3 DLC1 MACF1 EXOC2

5.92e-04205975EFO_0004832
Diseaseneuroblastoma

TDRD15 TRIM5 ARHGEF40 ANO7

5.93e-04116974EFO_0000621
Diseaselow density lipoprotein cholesterol measurement, phospholipid measurement

TDRD15 PLAUR ABCG8 MTARC1

6.73e-04120974EFO_0004611, EFO_0004639
Diseasephospholipids in IDL measurement

TDRD15 ABCG8 MTARC1

6.77e-0452973EFO_0022164
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

6.91e-0412972DOID:11726 (implicated_via_orthology)
Diseasetotal phospholipids in lipoprotein particles measurement

TDRD15 ABCG8 MTARC1

7.16e-0453973EFO_0022315
Diseasedevelopmental and epileptic encephalopathy (implicated_via_orthology)

STXBP1 STXBP2

8.15e-0413972DOID:0112202 (implicated_via_orthology)
Diseasefree cholesterol to total lipids in large HDL percentage

TDRD15 TRIM5 ABCG8

8.41e-0456973EFO_0022279
Diseaseplatelet component distribution width

POGK SYNE1 SPTA1 ARHGEF15 METTL24 DLC1 FAR2 NFE2L1 MACF1

8.63e-04755979EFO_0007984
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

TDRD15 BAZ1B TRIM5 ABCG8 MTARC1

8.99e-04225975EFO_0008317, EFO_0010351
Diseasecholesterol in IDL measurement

TDRD15 ABCG8 MTARC1

9.32e-0458973EFO_0021899
Diseasephospholipids:total lipids ratio

TDRD15 TRIM5 MACF1 ABCG8 MTARC1

9.36e-04227975EFO_0020946
Diseasetotal lipids in IDL

TDRD15 ABCG8 MTARC1

1.03e-0360973EFO_0022161
Diseasefree cholesterol in IDL measurement

TDRD15 ABCG8 MTARC1

1.08e-0361973EFO_0022181
Diseasepancreatitis

STXBP1 ABCG8

1.25e-0316972EFO_0000278
Diseaselow density lipoprotein cholesterol measurement, physical activity

TDRD15 ABCG8 MTARC1

1.36e-0366973EFO_0003940, EFO_0004611
Diseaseapolipoprotein B measurement

TDRD15 BAZ1B TRIM5 MYOF STXBP3 SYNE2 EPS8L3 ABCG8

1.56e-03663978EFO_0004615
Diseasecholesteryl ester measurement

TDRD15 BAZ1B TRIM5 ABCG8 MTARC1

1.62e-03257975EFO_0010351
DiseaseTNF-related apoptosis-inducing ligand measurement

ECT2 PLAUR MAPK9

1.74e-0372973EFO_0008300
DiseaseHypertriglyceridemia

TDRD15 BAZ1B

1.76e-0319972EFO_0004211
Diseasemigraine disorder, endometriosis

STXBP2 EXOC2 MAPK9

1.81e-0373973EFO_0001065, MONDO_0005277
Diseaseleft atrial function

CASQ2 MYO18B

2.16e-0321972EFO_0004294
Diseasesphingomyelin measurement

TDRD15 SPTLC1 SYNE2 ABCG8 MTARC1

2.28e-03278975EFO_0010118
Diseaselipoprotein measurement, phospholipid measurement

TDRD15 ABCG8 MTARC1

2.80e-0385973EFO_0004639, EFO_0004732
DiseaseWest Syndrome

SPTAN1 STXBP1

2.82e-0324972C0037769
Diseasefatty acid measurement

TDRD15 BAZ1B CHMP4A MACF1 ABCG8 MTARC1

3.21e-03436976EFO_0005110

Protein segments in the cluster

PeptideGeneStartEntry
IDAEEFEKSWLLLAD

TTC21B

1191

Q7Z4L5
EIKLKDWIENLEVDR

ABCA5

1531

Q8WWZ7
LIEVEKERLLDEWFT

ESYT2

476

A0FGR8
SVWEKEIEILIEENE

AKAP9

816

Q99996
KVDEDEEALKQLAEW

CHMP4A

206

Q9BY43
ARVEEEAWDLDVKQI

ARHGEF40

1446

Q8TER5
KLAGLVEELEADEWR

ANAPC16

81

Q96DE5
ERLVAEEAWVLTEEL

BAIAP3

636

O94812
WEEEQEVAELLKEEF

BAZ1B

66

Q9UIG0
FWKDIVDDNEVRDLI

ARID2

236

Q68CP9
LDDFLWKAETKDLDE

ABCG8

356

Q9H221
EEEGLEVLKEQNWEL

ARHGEF15

331

O94989
VEKEEERNDWISILL

ARAP2

556

Q8WZ64
EERALLEGEKALWED

CCDC70

166

Q6NSX1
AIKEEDLVVWVDPLD

BPNT1

106

O95861
EAEVERAIKDAFELW

MMP8

126

P22894
DLTKEDIDLIDILWR

NFE2L1

166

Q14494
DIDLIDILWRQDIDL

NFE2L1

171

Q14494
KDDLEDLIVNWDESK

ECT2

516

Q9H8V3
EEDRLKIDVIDWLVF

NUP107

666

P57740
DEIEEIKETLIDWCD

GPHN

61

Q9NQX3
SAKELEEWELRLQEE

ANKRD13A

561

Q8IZ07
DFVLVWEEDLKLDRQ

ANO7

111

Q6IWH7
KIIDSLEWLDDAIID

FAR2

176

Q96K12
QLEEREHAIEEWKEL

MAPK9

341

P45984
EDSWDELLIGDVELK

MTARC1

251

Q5VT66
ERDILAEADNEWVVK

LATS2

716

Q9NRM7
LEEANADLEVKIRDW

KRT14

136

P02533
LLEQWEKDDDIEEGD

MESD

66

Q14696
EKEEEESEEDWKLQL

NFKBIB

186

Q15653
EEIKRLAEKEDWIVD

EXOC2

596

Q96KP1
TALIDFWDKVLEEAE

PARG

571

Q86W56
WLQLLDIETKEELDS

EPS8L3

76

Q8TE67
LEEEDDVLWEIESEL

POGK

576

Q9P215
KIEDLTELEGWEELE

LIG3

156

P49916
EVIDHKLTEREWAEE

CBFA2T3

381

O75081
REDALELTEKLDQDW

NOP14

211

P78316
AELIWLNEKEEEELA

MACF1

691

Q9UPN3
WIEFEEIADLEERAK

PCF11

1391

O94913
EWLEGEDLSEELKKE

CKAP5

976

Q14008
ALEDRVWELLQEADK

CCDC141

76

Q6ZP82
EELEDWLEDVLEGEI

CASQ1

371

P31415
LLKDREPIEIEWDDL

CYP4F11

361

Q9HBI6
LETWEREKEKENLEL

CENPJ

561

Q9HC77
LLKDREPKEIEWDDL

CYP4F8

361

P98187
LLKDRDPKEIEWDDL

CYP4F12

361

Q9HCS2
LLKDREPKEIEWDDL

CYP4F2

361

P78329
LILVIIEDVEESIEW

IQCF2

11

Q8IXL9
DLPTAEELEDWIEDV

CASQ2

351

O14958
EELEDWIEDVLSGKI

CASQ2

356

O14958
LLKDREPKEIEWDDL

CYP4F3

361

Q08477
ESAEWKVLENLILED

METTL24

271

Q5JXM2
LDSLDVVNKDDIIEW

PGGT1B

61

P53609
HWDDIADLEEAKKLL

KATNAL1

206

Q9BW62
AQTILEKEAEDVIWE

RNASEH2A

241

O75792
LEALEAWIVEAEEIL

SYNE1

7361

Q8NF91
ELLLEDWHKFIEEKE

SYNE2

516

Q8WXH0
EQEKTLLELVEAWLE

TDO2

196

P48775
DAVWEVEILVDDLLL

TDRD15

1671

B5MCY1
EELVLRWEQLLLDEA

TAF1C

196

Q15572
EDAWALDDILVEFID

TDRD12

956

Q587J7
LVKLLREEEEWEATL

PNMA3

326

Q9UL41
KLEEELKARIELWEQ

PRC1

401

O43663
TAVLEEDSADWEKEL

SYAP1

306

Q96A49
QWEDGAEDILEKEEI

SUPT5H

91

O00267
ILALIDEGETDWKLI

PPA2

191

Q9H2U2
KEKEAILEEEDDLWV

STXBP3

276

O00186
VKEVLLDEDDDLWIA

STXBP1

276

P61764
LWDVDLLDSKVIEIL

DLC1

1391

Q96QB1
DLTVKEKEELIEEWQ

SPTLC1

51

O15269
DLEAVKVEEELTLSW

CLCA2

771

Q9UQC9
AIDGHEVILEKIEDW

C10orf53

36

Q8N6V4
EVILEKIEDWNVVEL

C10orf53

41

Q8N6V4
AEELEADIREEKASW

TRIM5

156

Q9C035
IFKLERGEELWILEE

ZNF157

76

P51786
VRLWEEGEELELVEK

PLAUR

51

Q03405
EPEELLIVKLEEDSW

ZSCAN20

16

P17040
WDTIRDEEDVLDELL

RALGAPA1

1671

Q6GYQ0
EAWAKLDVDRILDEL

RPAP3

91

Q9H6T3
NEKLEWAIDEDELRK

PSD2

461

Q9BQI7
WAIDEDELRKSLSEL

PSD2

466

Q9BQI7
EEKEDEELDWALASL

WDR97

1106

A6NE52
DILDQERADLEKAWV

SPTAN1

1421

Q13813
EKAVLLDEDDDLWVE

STXBP2

276

Q15833
LTALADLEDWEELEK

VPS16

731

Q9H269
DFWLLFDDDIVEKID

USP12

326

O75317
QAVKLERDDLEKAWE

SPTA1

1371

P02549
DLDDEESWIEEKLIR

SPTA1

1721

P02549
EDEDLIKWKALFEEV

ATIC

501

P31939
EAEDLEKSWLLLADI

TTC21A

1196

Q8NDW8
DDVLNDEELDKELLW

PSME4

661

Q14997
DEELDKELLWNLQLL

PSME4

666

Q14997
LWIDADKTITEVDEE

MYO18B

546

Q8IUG5
EEALLEEWLGLKTIA

ZNF862

986

O60290
LWKEDLATFIEELEA

TOP2A

1166

P11388
KSWEEVQLEDDRELL

ZNF277

271

Q9NRM2
EAEWQEILAKVKEEE

SFMBT1

241

Q9UHJ3
IAQLELEEEWVIERD

ZNF713

81

Q8N859
LEEEWVIERDSLLDT

ZNF713

86

Q8N859
WEALTEVLKEIEAEN

ERCC4

381

Q92889
EALRLLADEDWEKKI

TOGARAM1

1261

Q9Y4F4
KESKVLLEDLDWDVV

WDR87

1296

Q6ZQQ6
EEEEALAWQREKLSE

WDR87

1751

Q6ZQQ6
DEVEWILDLKEEENE

ZFYVE26

1906

Q68DK2
LSWEEVEDKLRAILE

TEX13B

41

Q9BXU2
AESELLIEDIIDNWK

TTLL7

701

Q6ZT98
GLWEVLDKEEVTALA

PP2D1

456

A8MPX8
QLAELWLKLIDEVIE

MYOF

686

Q9NZM1