Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	GABRG1 CACNA1C CACNA1F ABCC3 SLC22A25 SLC52A1 ABCA13 SLC39A11 SLC22A11 SLC35C2 SLC2A14 SLC7A7 SLC1A6 SLC2A2 SLC22A18 CLCN3 KCNQ5 SLC12A9 ABCC8 PKD1 SLC35F6 KCNQ2 SLC16A11 SLC2A13 CTNS GRIN3A MFSD10 CACNA2D3 SLC22A31	4.05e-10	1180	130	29	GO:0022857
GeneOntologyMolecularFunction	transporter activity	GABRG1 CACNA1C CACNA1F ABCC3 SLC22A25 SLC52A1 ABCA13 SLC39A11 SLC22A11 SLC35C2 SLC2A14 SLC7A7 SLC1A6 SLC2A2 SLC22A18 CLCN3 KCNQ5 SLC12A9 ABCC8 PKD1 SLC35F6 KCNQ2 SLC16A11 SLC2A13 CTNS GRIN3A MFSD10 CACNA2D3 SLC22A31	3.08e-09	1289	130	29	GO:0005215
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	ABCC3 SLC22A25 SLC52A1 SLC22A11 SLC2A14 SLC7A7 SLC1A6 SLC2A2 SLC22A18 SLC16A11 CTNS GRIN3A MFSD10	6.33e-08	293	130	13	GO:0008514
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	GABRG1 CACNA1C CACNA1F ABCC3 SLC39A11 SLC22A11 SLC1A6 CLCN3 KCNQ5 SLC12A9 ABCC8 PKD1 KCNQ2 SLC2A13 CTNS GRIN3A CACNA2D3	8.71e-06	758	130	17	GO:0015318
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCC3 SLC22A25 ABCA13 SLC22A11 SLC35C2 SLC1A6 SLC22A18 CLCN3 SLC12A9 ABCC8 SLC16A11 SLC2A13 CTNS	1.45e-05	477	130	13	GO:0022804
GeneOntologyMolecularFunction	heparan sulfate binding	COL11A1 GFRA2 FURIN	2.20e-05	9	130	3	GO:1904399
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC22A25 SLC22A11 SLC35C2 SLC1A6 SLC22A18 CLCN3 SLC12A9 SLC16A11 SLC2A13 CTNS	2.45e-05	296	130	10	GO:0015291
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1C CACNA1F CLCN3 KCNQ5 ABCC8 KCNQ2 GRIN3A CACNA2D3	2.57e-05	182	130	8	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1C CACNA1F CLCN3 KCNQ5 ABCC8 KCNQ2 GRIN3A CACNA2D3	2.78e-05	184	130	8	GO:0022832
GeneOntologyMolecularFunction	mannosyltransferase activity	POMT2 DPY19L2 TMTC3 ALG9	3.11e-05	28	130	4	GO:0000030
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	GABRG1 CACNA1C CACNA1F SLC39A11 SLC1A6 CLCN3 KCNQ5 SLC12A9 ABCC8 PKD1 KCNQ2 SLC2A13 CTNS GRIN3A CACNA2D3	2.04e-04	793	130	15	GO:0015075
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1C CACNA1F SLC39A11 SLC1A6 KCNQ5 SLC12A9 ABCC8 PKD1 KCNQ2 SLC2A13 CTNS GRIN3A CACNA2D3	2.31e-04	627	130	13	GO:0022890
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1C CACNA1F SLC39A11 SLC1A6 KCNQ5 SLC12A9 ABCC8 PKD1 KCNQ2 GRIN3A CACNA2D3	2.34e-04	465	130	11	GO:0046873
GeneOntologyMolecularFunction	gated channel activity	GABRG1 CACNA1C CACNA1F CLCN3 KCNQ5 ABCC8 KCNQ2 GRIN3A CACNA2D3	3.44e-04	334	130	9	GO:0022836
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1C CACNA1F SLC39A11 SLC1A6 KCNQ5 SLC12A9 ABCC8 PKD1 KCNQ2 SLC2A13 CTNS GRIN3A CACNA2D3	4.00e-04	664	130	13	GO:0008324
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	ABCC3 SLC22A25 SLC7A7 SLC1A6 SLC16A11 CTNS GRIN3A	4.19e-04	207	130	7	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	ABCC3 SLC22A25 SLC7A7 SLC1A6 SLC16A11 CTNS GRIN3A	4.31e-04	208	130	7	GO:0005342
GeneOntologyMolecularFunction	symporter activity	SLC1A6 SLC22A18 SLC12A9 SLC16A11 SLC2A13 CTNS	4.51e-04	150	130	6	GO:0015293
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1C CACNA1F KCNQ5 ABCC8 KCNQ2 CACNA2D3	4.84e-04	152	130	6	GO:0022843
GeneOntologyMolecularFunction	galactose transmembrane transporter activity	SLC2A14 SLC2A2	6.20e-04	6	130	2	GO:0005354
GeneOntologyMolecularFunction	monoatomic ion channel activity	GABRG1 CACNA1C CACNA1F CLCN3 KCNQ5 ABCC8 PKD1 KCNQ2 GRIN3A CACNA2D3	8.54e-04	459	130	10	GO:0005216
GeneOntologyMolecularFunction	dolichyl-phosphate-mannose-protein mannosyltransferase activity	POMT2 TMTC3	1.15e-03	8	130	2	GO:0004169
GeneOntologyMolecularFunction	dehydroascorbic acid transmembrane transporter activity	SLC2A14 SLC2A2	1.15e-03	8	130	2	GO:0033300
GeneOntologyMolecularFunction	calcium channel activity	CACNA1C CACNA1F PKD1 GRIN3A CACNA2D3	1.56e-03	129	130	5	GO:0005262
GeneOntologyMolecularFunction	vitamin transmembrane transporter activity	SLC52A1 SLC2A14 SLC2A2	1.65e-03	36	130	3	GO:0090482
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1C CACNA1F KCNQ5 ABCC8 PKD1 KCNQ2 GRIN3A CACNA2D3	1.85e-03	343	130	8	GO:0005261
GeneOntologyMolecularFunction	channel activity	GABRG1 CACNA1C CACNA1F CLCN3 KCNQ5 ABCC8 PKD1 KCNQ2 GRIN3A CACNA2D3	2.31e-03	525	130	10	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	GABRG1 CACNA1C CACNA1F CLCN3 KCNQ5 ABCC8 PKD1 KCNQ2 GRIN3A CACNA2D3	2.34e-03	526	130	10	GO:0022803
GeneOntologyMolecularFunction	protein phosphatase 2A binding	DAB2IP CACNA1C GRIN3A	2.57e-03	42	130	3	GO:0051721
GeneOntologyMolecularFunction	hexosyltransferase activity	POMT2 DPY19L2 UGT1A6 STT3A TMTC3 ALG9	2.61e-03	211	130	6	GO:0016758
GeneOntologyBiologicalProcess	organic anion transport	ABCC3 SLC22A25 SLC52A1 SLC22A11 SLC35C2 SLC2A14 SLC7A7 SLC1A6 SLC2A2 ABCC8 SLC16A11 TNF CTNS MFSD10	4.75e-06	515	130	14	GO:0015711
Domain	MFS	SLC22A25 SLC22A11 SLC2A14 MFSD6L SLC2A2 SLC22A18 SLC16A11 SLC2A13 MFSD10 SLC22A31	3.52e-09	108	128	10	PS50850
Domain	MFS_dom	SLC22A25 SLC22A11 SLC2A14 MFSD6L SLC2A2 SLC22A18 SLC16A11 SLC2A13 MFSD10 SLC22A31	2.85e-08	134	128	10	IPR020846
Domain	MFS_sugar_transport-like	SLC22A11 SLC2A14 SLC2A2 SLC2A13 SLC22A31	4.44e-06	36	128	5	IPR005828
Domain	Sugar_tr	SLC22A11 SLC2A14 SLC2A2 SLC2A13 SLC22A31	4.44e-06	36	128	5	PF00083
Domain	K_chnl_volt-dep_KCNQ2	KCNQ5 KCNQ2	4.66e-05	2	128	2	IPR003947
Domain	Sugar/inositol_transpt	SLC2A14 SLC2A2 SLC2A13	1.08e-04	14	128	3	IPR003663
Domain	CAC1F_C	CACNA1C CACNA1F	1.39e-04	3	128	2	IPR031688
Domain	CAC1F_C	CACNA1C CACNA1F	1.39e-04	3	128	2	PF16885
Domain	MFS_1	SLC22A25 SLC22A11 SLC22A18 SLC16A11 MFSD10	1.86e-04	77	128	5	PF07690
Domain	MFS	SLC22A25 SLC22A11 SLC22A18 SLC16A11 MFSD10	1.86e-04	77	128	5	IPR011701
Domain	SUGAR_TRANSPORT_2	SLC2A14 SLC2A2 SLC2A13	1.99e-04	17	128	3	PS00217
Domain	VDCC_L_a1su	CACNA1C CACNA1F	2.77e-04	4	128	2	IPR005446
Domain	WSC	WSCD1 PKD1	4.60e-04	5	128	2	SM00321
Domain	K_chnl_volt-dep_KCNQ_C	KCNQ5 KCNQ2	4.60e-04	5	128	2	IPR013821
Domain	WSC	WSCD1 PKD1	4.60e-04	5	128	2	PS51212
Domain	WSC_carb-bd	WSCD1 PKD1	4.60e-04	5	128	2	IPR002889
Domain	WSC	WSCD1 PKD1	4.60e-04	5	128	2	PF01822
Domain	K_chnl_volt-dep_KCNQ	KCNQ5 KCNQ2	4.60e-04	5	128	2	IPR003937
Domain	KCNQ_channel	KCNQ5 KCNQ2	4.60e-04	5	128	2	PF03520
Domain	LRRNT	LINGO3 LGR5 PKD1 GP1BA	4.75e-04	53	128	4	PF01462
Domain	SUGAR_TRANSPORT_1	SLC2A14 SLC2A2 SLC2A13	5.73e-04	24	128	3	PS00216
Domain	Ca_chan_IQ	CACNA1C CACNA1F	9.57e-04	7	128	2	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1F	9.57e-04	7	128	2	PF08763
Domain	VDCC_a1su_IQ	CACNA1C CACNA1F	9.57e-04	7	128	2	IPR014873
Domain	GPHH	CACNA1C CACNA1F	9.57e-04	7	128	2	PF16905
Domain	GPHH_dom	CACNA1C CACNA1F	9.57e-04	7	128	2	IPR031649
Domain	Sugar_transporter_CS	SLC2A14 SLC2A2 SLC2A13	1.35e-03	32	128	3	IPR005829
Domain	VDCCAlpha1	CACNA1C CACNA1F	2.02e-03	10	128	2	IPR002077
Domain	BAH	ORC1 MTA3	2.46e-03	11	128	2	PS51038
Domain	BAH_dom	ORC1 MTA3	2.46e-03	11	128	2	IPR001025
Domain	BAH	ORC1 MTA3	2.46e-03	11	128	2	SM00439
Domain	BAH	ORC1 MTA3	2.46e-03	11	128	2	PF01426
Domain	VWA	ITGA1 VWA7 HMCN2 CACNA2D3	2.66e-03	84	128	4	SM00327
Domain	C8	SSPOP FCGBP	2.94e-03	12	128	2	PF08742
Domain	TIL	SSPOP FCGBP	2.94e-03	12	128	2	PF01826
Domain	Unchr_dom_Cys-rich	SSPOP FCGBP	3.46e-03	13	128	2	IPR014853
Domain	C8	SSPOP FCGBP	3.46e-03	13	128	2	SM00832
Domain	TIL_dom	SSPOP FCGBP	4.02e-03	14	128	2	IPR002919
Domain	ABC_tran	ABCC3 ABCA13 ABCC8	4.34e-03	48	128	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCC3 ABCA13 ABCC8	4.34e-03	48	128	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCC3 ABCA13 ABCC8	4.60e-03	49	128	3	PS00211
Domain	LRRNT	LINGO3 LGR5 PKD1 GP1BA	4.63e-03	98	128	4	IPR000372
Domain	LRRNT	LINGO3 LGR5 PKD1 GP1BA	4.63e-03	98	128	4	SM00013
Domain	VWF_A	ITGA1 VWA7 HMCN2 CACNA2D3	4.80e-03	99	128	4	IPR002035
Domain	ABC_transporter-like	ABCC3 ABCA13 ABCC8	4.87e-03	50	128	3	IPR003439
Domain	VWF_type-D	SSPOP FCGBP	5.25e-03	16	128	2	IPR001846
Domain	VWFD	SSPOP FCGBP	5.25e-03	16	128	2	PS51233
Domain	VWD	SSPOP FCGBP	5.25e-03	16	128	2	SM00216
Domain	VWD	SSPOP FCGBP	5.25e-03	16	128	2	PF00094
Domain	-	NLRP12 LINGO3 PRAMEF1 LGR5 NLRP6 PKD1 GP1BA	6.68e-03	321	128	7	3.80.10.10
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNA1C CACNA1F CLCN3 KCNQ5 ABCC8 KCNQ2 CACNA2D3	1.09e-06	139	132	7	16985003
Pubmed	Decreased expression of Glucagon-like peptide-1 receptor and Sodium-glucose co-transporter 2 in patients with proliferative diabetic retinopathy.	SLC2A2 GLP1R TNF	1.85e-06	7	132	3	36465606
Pubmed	Polycystic Kidney Disease, Autosomal Dominant	GANAB ALG9 PKD1	1.85e-06	7	132	3	20301424
Pubmed	Nerve Growth Factor Promotes Gastric Tumorigenesis through Aberrant Cholinergic Signaling.	LGR5 PRKDC DCLK1	2.95e-06	8	132	3	27989802
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	NAT14 VEZT UBR4 STT3A THADA GANAB TMTC3 SLC12A9 TMEM259 EIF2B5 DDRGK1 TNF HADHA PRKDC ESPL1	3.14e-06	942	132	15	31073040
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	POMT2 ABCC3 NAT14 ERO1B ITGA1 STT3A DMXL1 EDEM3 COL18A1 THADA GANAB TMTC3 TMEM259 SUN2 FURIN ALG9 JMJD8	3.23e-06	1201	132	17	35696571
Pubmed	BMP4-BMPR1A signaling in beta cells is required for and augments glucose-stimulated insulin secretion.	SLC2A2 CAPN10 ABCC8 GLP1R	4.37e-06	29	132	4	17339028
Pubmed	Substantial changes in gene expression of Wnt, MAPK and TNFalpha pathways induced by TGF-beta1 in cervical cancer cell lines.	WNT2 TNF	1.43e-05	2	132	2	15878915
Pubmed	Polymorphisms in platelet glycoprotein 1balpha and factor VII and risk of ischemic stroke: a meta-analysis.	F7 GP1BA	1.43e-05	2	132	2	18403734
Pubmed	Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis.	NLRP12 NLRP6	1.43e-05	2	132	2	24338634
Pubmed	Insulinoma induces a hyperinsulinemia-mediated decrease of GLUT2 and GLP1 receptor in normal pancreatic β-cells.	SLC2A2 GLP1R	1.43e-05	2	132	2	33199025
Pubmed	Exendin-(9-39) corrects fasting hypoglycemia in SUR-1-/- mice by lowering cAMP in pancreatic beta-cells and inhibiting insulin secretion.	ABCC8 GLP1R	1.43e-05	2	132	2	18635551
Pubmed	Upregulation of circulating cancer stem cell marker, DCLK1 but not Lgr5, in chemoradiotherapy-treated colorectal cancer patients.	LGR5 DCLK1	1.43e-05	2	132	2	25631749
Pubmed	Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells.	TNF PRKDC	1.43e-05	2	132	2	18936235
Pubmed	The interaction of recombinant factor VIIa with platelet glycoprotein Ib.	F7 GP1BA	1.43e-05	2	132	2	20153024
Pubmed	Importance of innate immunity and collagen binding integrin alpha1beta1 in TNBS-induced colitis.	ITGA1 PRKDC	1.43e-05	2	132	2	12479823
Pubmed	Analysis of differentially expressed genes and microRNAs in alcoholic liver disease.	FZD5 ACSF3	1.43e-05	2	132	2	23337955
Pubmed	Physical activity modifies the effect of SNPs in the SLC2A2 (GLUT2) and ABCC8 (SUR1) genes on the risk of developing type 2 diabetes.	SLC2A2 ABCC8	1.43e-05	2	132	2	17636114
Pubmed	KCNQ2 and KCNQ5 form heteromeric channels independent of KCNQ3.	KCNQ5 KCNQ2	1.43e-05	2	132	2	35320039
Pubmed	Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability.	CACNA1C PKD1	1.43e-05	2	132	2	25888683
Pubmed	DCLK1, a Putative Stem Cell Marker in Human Cholangiocarcinoma.	LGR5 DCLK1	1.43e-05	2	132	2	32978808
Pubmed	Genetic Association Study Between the COL11A1 and COL18A1 Genes and High Myopia in a Han Chinese Population.	COL11A1 COL18A1	1.43e-05	2	132	2	29781737
Pubmed	T cell receptor zeta reconstitution fails to restore responses of T cells rendered hyporesponsive by tumor necrosis factor alpha.	CD247 TNF	1.43e-05	2	132	2	14745016
Pubmed	Role of doublecortin-like kinase 1 and leucine-rich repeat-containing G-protein-coupled receptor 5 in patients with stage II/III colorectal cancer: Cancer progression and prognosis.	LGR5 DCLK1	1.43e-05	2	132	2	33268966
Pubmed	Induced repatterning of type XVIII collagen expression in ureter bud from kidney to lung type: association with sonic hedgehog and ectopic surfactant protein C.	WNT2 COL18A1	1.43e-05	2	132	2	11290296
Pubmed	Lgr5High/DCLK1High phenotype is more common in early stage and intestinal subtypes of gastric carcinomas.	LGR5 DCLK1	1.43e-05	2	132	2	28946555
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DAB2IP ABCC3 SPEG UBR4 KAT2A ORC1 THADA TMEM259 FURIN NFKB2 PKD1 KCNQ2 PRKDC ESPL1 RAD9A	2.08e-05	1105	132	15	35748872
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1C CACNA1F CACNA2D3	2.35e-05	15	132	3	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1C CACNA1F CACNA2D3	2.35e-05	15	132	3	24453333
Pubmed	Small intestinal resident eosinophils maintain gut homeostasis following microbial colonization.	SIGLEC14 PRKDC DCLK1	3.50e-05	17	132	3	35709757
Pubmed	Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.	NLRP12 NLRP6 TNF	3.50e-05	17	132	3	22297845
Pubmed	Restoring multidrug resistance-associated protein 3 attenuates cell proliferation in the polycystic kidney.	ABCC3 PKD1	4.28e-05	3	132	2	25143454
Pubmed	Anteroposterior Patterning of Gene Expression in the Human Infant Sclera: Chondrogenic Potential and Wnt Signaling.	COL11A1 WNT2	4.28e-05	3	132	2	27336854
Pubmed	Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5(+) stem cells.	LGR5 FZD5	4.28e-05	3	132	2	25892522
Pubmed	Tonic TNF conditioning of macrophages safeguards stimulus-specific inflammatory responses.	NFKB2 TNF	4.28e-05	3	132	2	37212045
Pubmed	Lymphocytes mediate TNF-alpha-induced endothelial cell adhesion molecule expression: studies on SCID and RAG-1 mutant mice.	TNF PRKDC	4.28e-05	3	132	2	9366433
Pubmed	Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes.	NLRP12 NFKB2	4.28e-05	3	132	2	17237370
Pubmed	Induced Quiescence of Lgr5+ Stem Cells in Intestinal Organoids Enables Differentiation of Hormone-Producing Enteroendocrine Cells.	LGR5 DCLK1	4.28e-05	3	132	2	27939219
Pubmed	Type XVIII collagen is essential for survival during acute liver injury in mice.	ITGA1 COL18A1	4.28e-05	3	132	2	23580202
Pubmed	Instability at the FRA8I common fragile site disrupts the genomic integrity of the KIAA0146, CEBPD and PRKDC genes in colorectal cancer.	PRKDC SPIDR	4.28e-05	3	132	2	23603433
Pubmed	AIP1 mediates TNF-alpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3.	DAB2IP TNF	4.28e-05	3	132	2	12813029
Pubmed	Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation.	KCNQ5 KCNQ2	4.28e-05	3	132	2	12890507
Pubmed	Distribution of furin, TNF-α, and TGF-β2 in the endometrium of missed abortion and voluntary first trimester termination cases.	FURIN TNF	4.28e-05	3	132	2	26065233
Pubmed	Genome-wide meta-analysis identifies BARX1 and EML4-MTA3 as new loci associated with infantile hypertrophic pyloric stenosis.	EML4 MTA3	4.28e-05	3	132	2	30281099
Pubmed	TNFα-Induced Expression of Transport Protein Genes in HUVEC Cells Is Associated with Enhanced Expression of Transcription Factor Genes RELB and NFKB2 of the Non-Canonical NF-κB Pathway.	NFKB2 TNF	4.28e-05	3	132	2	29658079
Pubmed	And-1 is required for the stability of histone acetyltransferase Gcn5.	KAT2A WDHD1	4.28e-05	3	132	2	21725360
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	DPY19L2 PLEKHG4 VEZT EML4 SNX17 PGM1 STT3A THADA FURIN SLC35F6 GNAL PRKDC MFSD10 SCAI	5.40e-05	1061	132	14	33845483
Pubmed	Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen.	F7 TNF GP1BA	7.81e-05	22	132	3	12871600
Pubmed	A DNA pooling-based case-control study of myopia candidate genes COL11A1, COL18A1, FBN1, and PLOD1 in a Chinese population.	COL11A1 COL18A1	8.54e-05	4	132	2	21527992
Pubmed	Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15.	TNF PRKDC	8.54e-05	4	132	2	20430958
Pubmed	Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-α.	GLP1R HADHA	8.54e-05	4	132	2	31985487
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1C CACNA1F	8.54e-05	4	132	2	20937870
Pubmed	Effect of the proinflammatory cytokine TNF-α on intestinal riboflavin uptake: inhibition mediated via transcriptional mechanism(s).	SLC52A1 TNF	8.54e-05	4	132	2	30156861
Pubmed	Genetic risk for ischemic and hemorrhagic stroke.	PKD1 TNF	8.54e-05	4	132	2	16741147
Pubmed	Endotoxin-induced enhancement of glucose influx into murine peritoneal macrophages via GLUT1.	SLC2A14 SLC2A2	8.54e-05	4	132	2	8557327
Pubmed	Glucose uptake, utilization, and signaling in GLUT2-null islets.	SLC2A14 SLC2A2	8.54e-05	4	132	2	10969832
Pubmed	p100 Deficiency is insufficient for full activation of the alternative NF-κB pathway: TNF cooperates with p52-RelB in target gene transcription.	NFKB2 TNF	8.54e-05	4	132	2	22880094
Pubmed	Changes in Expression of Follicular Glucose Transporters May Be Involved in Ovarian Function Impairment during Diabetic Hyperglycemia.	SLC2A14 SLC2A2	8.54e-05	4	132	2	31882430
Pubmed	The glycoprotein Ib-IX-V complex contributes to tissue factor-independent thrombin generation by recombinant factor VIIa on the activated platelet surface.	F7 GP1BA	8.54e-05	4	132	2	18612104
Pubmed	Activating Hair Follicle Stem Cells via R-spondin2 to Stimulate Hair Growth.	LGR5 PRKDC	8.54e-05	4	132	2	27109869
Pubmed	Glucose transporter expression and functional role of hexokinase in insulin biosynthesis in mouse beta TC3 cells.	SLC2A14 SLC2A2	8.54e-05	4	132	2	7653530
Pubmed	Isolated polycystic liver disease genes define effectors of polycystin-1 function.	GANAB PKD1	8.54e-05	4	132	2	28375157
Pubmed	Maternal hyperglycemia alters glucose transport and utilization in mouse preimplantation embryos.	SLC2A14 SLC2A2	8.54e-05	4	132	2	9688872
Pubmed	Expression of pro-inflammatory TACE-TNF-α-amphiregulin axis in Sjögren's syndrome salivary glands.	FURIN TNF	8.54e-05	4	132	2	20811902
Pubmed	Phosphorylation of p50 NF-kappaB at a single serine residue by DNA-dependent protein kinase is critical for VCAM-1 expression upon TNF treatment.	TNF PRKDC	8.54e-05	4	132	2	20966071
Pubmed	Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.	LGR5 FZD5	8.54e-05	4	132	2	22895187
Pubmed	Notch signaling drives development of Barrett's metaplasia from Dclk1-positive epithelial tuft cells in the murine gastric mucosa.	LGR5 DCLK1	8.54e-05	4	132	2	33627749
Pubmed	TNF-alpha is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice.	TNF PRKDC	8.54e-05	4	132	2	15578092
Pubmed	Tumor necrosis factor stimulates fibroblast growth factor 23 levels in chronic kidney disease and non-renal inflammation.	PKD1 TNF	8.54e-05	4	132	2	31301888
Pubmed	Brief Report: Immune Microenvironment Determines the Immunogenicity of Induced Pluripotent Stem Cell Derivatives.	CD247 PRKDC	8.54e-05	4	132	2	26439188
Pubmed	Nutrient Transporter Gene Expression in the Early Conceptus-Implications From Two Mouse Models of Diabetic Pregnancy.	SLC2A14 SLC2A2 SLC2A13	1.16e-04	25	132	3	35478964
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CACNA1F UBR4 PTGER1 SSPOP PGM1 FRY DROSHA PKD1 HADHA PRKDC GP1BA	1.21e-04	736	132	11	29676528
Pubmed	TNFα signaling regulates cystic epithelial cell proliferation through Akt/mTOR and ERK/MAPK/Cdk2 mediated Id2 signaling.	PKD1 TNF	1.42e-04	5	132	2	26110849
Pubmed	GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion.	SLC2A2 GLP1R	1.42e-04	5	132	2	17681422
Pubmed	Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment.	NLRP12 NLRP6	1.42e-04	5	132	2	27779193
Pubmed	Enhanced nuclear factor-kappa B activation induced by tumour necrosis factor-alpha in stably tat-transfected cells is associated with the presence of cell-surface-bound Tat protein.	NFKB2 TNF	1.42e-04	5	132	2	8724035
Pubmed	The contribution of Kv7 channels to pregnant mouse and human myometrial contractility.	KCNQ5 KCNQ2	1.42e-04	5	132	2	20132415
Pubmed	Differential screening of a PCR-generated mouse embryo cDNA library: glucose transporters are differentially expressed in early postimplantation mouse embryos.	SLC2A14 SLC2A2	1.42e-04	5	132	2	1289053
Pubmed	B cell production of tumor necrosis factor in response to Pneumocystis murina infection in mice.	TNF PRKDC	1.42e-04	5	132	2	24002064
Pubmed	Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study.	SLC2A2 CAPN10	1.42e-04	5	132	2	20142250
Pubmed	MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor.	F7 TNF	1.42e-04	5	132	2	24998411
Pubmed	Cutting edge: Nlrp10 is essential for protective antifungal adaptive immunity against Candida albicans.	NLRP12 NLRP6	1.42e-04	5	132	2	23071280
Pubmed	Dclk1 distinguishes between tumor and normal stem cells in the intestine.	LGR5 DCLK1	1.42e-04	5	132	2	23202126
Pubmed	Genetic factors associated with rheumatoid arthritis and systemic vasculitis: Evaluation of a panel of polymorphisms.	NFKB2 TNF	1.42e-04	5	132	2	20037209
Pubmed	An Anti-Inflammatory Role for NLRP10 in Murine Cutaneous Leishmaniasis.	NLRP12 NLRP6	1.42e-04	5	132	2	28931602
Pubmed	Developmental expression and cellular localization of glucose transporter molecules during mouse preimplantation development.	SLC2A14 SLC2A2	1.42e-04	5	132	2	1638987
Pubmed	Dual phosphorylations underlie modulation of unitary KCNQ K(+) channels by Src tyrosine kinase.	KCNQ5 KCNQ2	1.42e-04	5	132	2	15304482
Pubmed	NF-kappaB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism.	NFKB2 TNF	1.42e-04	5	132	2	19770515
Pubmed	The glucose transporter family: structure, function and tissue-specific expression.	SLC2A14 SLC2A2	1.42e-04	5	132	2	8240230
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	NLRP12 PRAMEF1 PRAMEF14	1.63e-04	28	132	3	25089626
Pubmed	Iron chelation decreases human immunodeficiency virus-1 Tat potentiated tumor necrosis factor-induced NF-kappa B activation in Jurkat cells.	NFKB2 TNF	2.12e-04	6	132	2	9110146
Pubmed	Molecular identification and functional characterization of the vitamin C transporters expressed by Sertoli cells.	SLC2A14 SLC2A2	2.12e-04	6	132	2	18668520
Pubmed	Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression.	NFKB2 TNF	2.12e-04	6	132	2	15660126
Pubmed	Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex.	KAT2A PRKDC	2.12e-04	6	132	2	9488450
Pubmed	T cells are essential for bacterial clearance, and gamma interferon, tumor necrosis factor alpha, and B cells are crucial for disease development in Coxiella burnetii infection in mice.	TNF PRKDC	2.12e-04	6	132	2	17438029
Pubmed	NLRC4 suppresses melanoma tumor progression independently of inflammasome activation.	NLRP12 NLRP6	2.12e-04	6	132	2	27617861
Pubmed	HIV type 1 Tat inhibits tumor necrosis factor alpha-induced repression of tumor necrosis factor receptor p55 and amplifies tumor necrosis factor alpha activity in stably tat-transfected HeLa Cells.	NFKB2 TNF	2.12e-04	6	132	2	11522182
Pubmed	The shedding activity of ADAM17 is sequestered in lipid rafts.	FURIN TNF	2.12e-04	6	132	2	17010968
Pubmed	The stability of histone acetyltransferase general control non-derepressible (Gcn) 5 is regulated by Cullin4-RING E3 ubiquitin ligase.	KAT2A WDHD1	2.12e-04	6	132	2	21987584
Pubmed	NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB.	NFKB2 PRKDC	2.12e-04	6	132	2	24892805
GeneFamily	Solute carriers	SLC22A25 SLC52A1 SLC39A11 SLC22A11 SLC35C2 SLC2A14 SLC7A7 SLC1A6 SLC2A2 SLC22A18 SLC12A9 SLC16A11 SLC2A13 SLC22A31	5.71e-09	395	87	14	752
GeneFamily	Calcium voltage-gated channel subunits	CACNA1C CACNA1F CACNA2D3	2.58e-04	26	87	3	253
GeneFamily	Dolichyl D-mannosyl phosphate dependent mannosyltransferases\|Phosphatidylinositol glycan anchor biosynthesis	POMT2 ALG9	8.06e-04	9	87	2	430
GeneFamily	ATP binding cassette subfamily C	ABCC3 ABCC8	1.72e-03	13	87	2	807
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-midbrain/hindbrain_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	GABRG1 SYNDIG1L NLRP12 EXOC3L1 GNAL GRIN3A CACNA2D3	3.95e-07	154	132	7	df1b58a20af73fa79c6c069c0117a9ffd85b476f
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNDIG1L LINGO3 KCNQ5 KCNQ2 GNAL SLC2A13 CACNA2D3	1.22e-06	182	132	7	d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNDIG1L LINGO3 KCNQ5 KCNQ2 GNAL SLC2A13 CACNA2D3	1.22e-06	182	132	7	6cde859edfe7607bd7ada89d20258413d06f4207
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	CACNA1C SLC39A11 SPEG ITGA1 FRY HMCN2 KCNQ5	1.26e-06	183	132	7	818fd886e0188091310825f9145fa53328f2c979
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 SYNDIG1L LINGO3 KCNQ5 KCNQ2 GNAL CACNA2D3	1.56e-06	189	132	7	3e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 SYNDIG1L LINGO3 KCNQ5 KCNQ2 GNAL CACNA2D3	1.56e-06	189	132	7	851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 SYNDIG1L LINGO3 KCNQ5 KCNQ2 GNAL CACNA2D3	1.62e-06	190	132	7	1c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCell	NS-moderate-d_16-33-Lymphoid-Treg\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EML4 PHTF2 GIMAP1 TBC1D10C CD247 SUN2 TNF	1.74e-06	192	132	7	48d557071bad80edd3ec6e5ad8dcd97037da9553
ToppCell	moderate-Lymphoid-Treg\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	EML4 PHTF2 GIMAP1 TBC1D10C CD247 SUN2 TNF	1.74e-06	192	132	7	e370ff5aaff7b7042ba9aaf93de43aa563b8b9f9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C FRY KCNQ5 PKD1 SLC2A13 DCLK1 SCAI	1.99e-06	196	132	7	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C FRY KCNQ5 PKD1 SLC2A13 DCLK1 CACNA2D3	2.13e-06	198	132	7	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1C FRY KCNQ5 PKD1 SLC2A13 DCLK1 SCAI	2.28e-06	200	132	7	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNDIG1L KCNQ5 ABCC8 KCNQ2 GNAL CACNA2D3	1.10e-05	168	132	6	b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNDIG1L KCNQ5 ABCC8 KCNQ2 GNAL CACNA2D3	1.10e-05	168	132	6	b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DAB2IP CACNA1C ITGA1 COL18A1 FRY GLP1R	1.34e-05	174	132	6	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	droplet-Limb_Muscle-nan-24m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KAT2A SSPOP TMEM88B KCNQ5 EXOC3L1 SLC2A13	1.53e-05	178	132	6	f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCell	Posterior_cortex-Hematopoietic-MICROGLIA\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CACNA1F DYRK4 SLC7A7 TNF ESPL1 NCKAP1L	1.58e-05	179	132	6	5122fc794509492afde4af8b1b76d51e3070ef05
ToppCell	NS-moderate-d_0-4-Lymphoid-CTL\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GIMAP1 ITGA1 TBC1D10C CD247 TNF NCKAP1L	1.68e-05	181	132	6	7fb3c1d29c542a3cea7fa654432d501d82df138f
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 SYNDIG1L WNT2 KCNQ5 GNAL CACNA2D3	1.79e-05	183	132	6	bf7f1cb55ed55981b8b355d5774055c96e658ff2
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 SYNDIG1L WNT2 KCNQ5 GNAL CACNA2D3	1.79e-05	183	132	6	9533db4db2c6ae78d7ca1682cf4efed12183396f
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	CACNA1C SLC39A11 ITGA1 FRY HMCN2 KCNQ5	1.79e-05	183	132	6	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DAB2IP CACNA1C ITGA1 COL18A1 KCNQ5 GNAL	1.90e-05	185	132	6	a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	WDR76 KCNQ5 WDHD1 BFSP2 ESPL1 PIF1	1.90e-05	185	132	6	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NAT14 DDIT4L LGR5 COL18A1 FCGBP MFSD10	1.90e-05	185	132	6	6da9a06e1514d5d5f47359a14637f02539846096
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NAT14 DDIT4L LGR5 COL18A1 FCGBP MFSD10	1.90e-05	185	132	6	4a188e2566a75d1b4f3c879a8c241c277c4b451c
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DAB2IP CACNA1C ITGA1 COL18A1 KCNQ5 GNAL	2.02e-05	187	132	6	a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCell	NS-control-d_0-4-Lymphoid-CTL\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GIMAP1 ITGA1 TBC1D10C CD247 TNF NCKAP1L	2.27e-05	191	132	6	27f2151da2f41015a979499f274ab1284a36189f
ToppCell	control-Lymphoid-CTL\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GIMAP1 ITGA1 TBC1D10C CD247 TNF NCKAP1L	2.27e-05	191	132	6	8df23473e24cfa51c09986102ddd391ed0f0b9cc
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	CACNA1C SPEG ITGA1 COL18A1 FRY GLP1R	2.27e-05	191	132	6	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	NS-control-d_0-4-Lymphoid-Treg\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GIMAP1 ITGA1 TBC1D10C CD247 TNF NCKAP1L	2.34e-05	192	132	6	ef252dd9df161f665f53c047c0514381f80d6683
ToppCell	control-Lymphoid-Treg\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GIMAP1 ITGA1 TBC1D10C CD247 TNF NCKAP1L	2.34e-05	192	132	6	9067e90b7c2d734100d6e5026d753113bf9428a3
ToppCell	moderate-Lymphoid-CTL\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GIMAP1 ITGA1 TBC1D10C CD247 SUN2 TNF	2.41e-05	193	132	6	3fce0807631811da1cff5ca9db23ff1ad36020e7
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 ABCC3 FCGBP CLCN3 ABCC8 KLHDC7A	2.41e-05	193	132	6	1526f51b589a7dc7a28f35f0e788dc38d338d2bc
ToppCell	NS-moderate-d_16-33-Lymphoid-CTL\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GIMAP1 ITGA1 TBC1D10C CD247 SUN2 TNF	2.48e-05	194	132	6	6b2bb3dd11fd53fa9ab4d66c18b0714f96f99288
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EML4 GIMAP1 TBC1D10C CD247 SUN2 MRPL1	2.48e-05	194	132	6	13c3674d601c8a7355ce869de1af6401938c0037
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNDIG1L ERO1B SLC2A2 ABCC8 GLP1R SLC2A13	2.55e-05	195	132	6	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	PSB-critical-LOC-Lymphoid-CTL\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GIMAP1 ITGA1 TBC1D10C CD247 TNF NCKAP1L	2.55e-05	195	132	6	e585d264dec3010134bb6aecbed85b2256f23c79
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	WDR76 CD247 KCNQ5 WDHD1 ESPL1 PIF1	2.55e-05	195	132	6	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	control-Lymphoid\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GIMAP1 ITGA1 TBC1D10C CD247 TNF NCKAP1L	2.63e-05	196	132	6	8ed172bb3a95f09722476f0880ae246561777d98
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C COL11A1 SPEG AGPAT4 ITGA1 KCNQ5	2.70e-05	197	132	6	f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell	NS-control-d_0-4-Lymphoid\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GIMAP1 ITGA1 TBC1D10C CD247 TNF NCKAP1L	2.70e-05	197	132	6	bd3f2d68eb108fe31e217c9124183920e7c82582
ToppCell	Mild/Remission-B_memory-3\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PHTF2 KAT2A COL18A1 CD247 NFKB2 MFSD10	2.78e-05	198	132	6	44906dbf99ddd53335e2d32082ff7e77d91baaeb
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C FRY KCNQ5 DCLK1 CACNA2D3 SCAI	2.78e-05	198	132	6	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Mild/Remission-B_memory-3\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	KAT2A TBC1D10C COL18A1 CD247 NFKB2 MFSD10	2.86e-05	199	132	6	493d043beef70b60338cc199db82592cdc6e635d
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C SPEG ITGA1 COL18A1 FRY HMCN2	2.94e-05	200	132	6	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Stem_cells-Neuroepithelial_cell\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	PLEKHG4 VWA7 WDR76 ORC1 ESPL1 PIF1	2.94e-05	200	132	6	c9c832f489629b8724501ddfede984b41a7b674d
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Stem_cells\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	PLEKHG4 VWA7 WDR76 ORC1 ESPL1 PIF1	2.94e-05	200	132	6	d7832ab1ed0ff0a6f7e3ac11b2095dc72c90af44
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells-iNKT-MAIT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL11A1 VWA7 TBC1D10C CD247 KCNQ5	4.97e-05	134	132	5	92981dc68c1b3cdc53f9cf83386c47f0c6c98ae7
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPY19L2 WNT2 SSPOP FCGBP SYTL5	7.96e-05	148	132	5	f58804d24fe524b42b5090c8658050ea4b14793e
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	CACNA1F F7 COL18A1 FZD5 GLP1R	8.48e-05	150	132	5	98fdc6bdfde84d680e11d8727502b79afbf64303
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B\|343B / Donor, Lineage, Cell class and subclass (all cells)	CACNA1F F7 TBC1D10C CD247 GLP1R	9.60e-05	154	132	5	886e7cd01cb48ca3e97debeea2b1f100b09d47e6
ToppCell	droplet-Thymus-nan-18m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1B VWA7 FZD5 NFKB2 BFSP2	1.05e-04	157	132	5	a9e077f686382303f0437ebfa4f11d273ba9fe40
ToppCell	facs-Trachea-nan-18m-Myeloid-lymphocyte_of_B_lineage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNDIG1L GIMAP1 SLC7A7 IZUMO1 BFSP2	1.15e-04	160	132	5	5c9281706009558c8361bfa76169f43ffc0f7947
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	CACNA1C ITGA1 COL18A1 FRY SLC22A31	1.15e-04	160	132	5	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PHTF2 FRY KCNQ5 ABCC8 GRIN3A	1.18e-04	161	132	5	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	CACNA1C ITGA1 COL18A1 HMCN2 SLC22A31	1.18e-04	161	132	5	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	facs-Trachea-18m-Hematologic-lymphocytic-B_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYNDIG1L GIMAP1 SLC7A7 IZUMO1 BFSP2	1.29e-04	164	132	5	4274a4f225cabf61f0fe27d8ea162b4eba612f87
ToppCell	facs-Trachea-18m-Hematologic-lymphocytic-B_cell-B_cell_of_the_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYNDIG1L GIMAP1 SLC7A7 IZUMO1 BFSP2	1.29e-04	164	132	5	d62143450f59097ad4b34603a6257f897a769ead
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PHTF2 ITGA1 KCNQ5 ABCC8 GRIN3A	1.29e-04	164	132	5	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C SPEG ITGA1 PTGER1 GLP1R	1.33e-04	165	132	5	8a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	DAB2IP CACNA1C SPEG COL18A1 HMCN2	1.40e-04	167	132	5	c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LGALS12 SLC1A6 SYTL5 SLC16A11 PIF1	1.40e-04	167	132	5	a90f905ef38437752e2b0b71bd0322a184de1861
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-NK_T_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GIMAP1 ITGA1 TBC1D10C CD247 PIF1	1.44e-04	168	132	5	b4b73f3fc9f4c3d87ca0a63ff8b2842141ccd0e6
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NAALADL1 SIGLEC14 SLC7A7 TBC1D10C ZNF792	1.48e-04	169	132	5	818ab7a6fd1940a22d3bd99fe15f0af888af6b3e
ToppCell	droplet-Lung-nan-3m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ORC1 TBC1D10C CD247 WDHD1 PIF1	1.48e-04	169	132	5	df2c9c706bfc9db2bc5726602a49f5f5a94e9481
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ORC1 TBC1D10C CD247 WDHD1 PIF1	1.48e-04	169	132	5	f6a6d2f614d60395ad9b867ff1cf59eba72b04ce
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NAALADL1 SIGLEC14 SLC7A7 TBC1D10C ZNF792	1.48e-04	169	132	5	f982f2e0d341fa27229f443ebe5c0e4a9e63bda6
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC3 MFSD6L EDEM3 FCGBP SYTL5	1.52e-04	170	132	5	2c5a1469e5743870e96e6c2cc92f0c5096b79f51
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC3 MFSD6L EDEM3 FCGBP SYTL5	1.52e-04	170	132	5	9bea81031cdfe45e8cddac3a3afd9ca6c331c45a
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Endothelial-new-cluster\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WSCD1 ITGA1 PTGER1 GLP1R EXOC3L1	1.52e-04	170	132	5	4fb4ce46e4fa2418238e264875209d7ebe844d82
ToppCell	TCGA-Cervix\|World / Sample_Type by Project: Shred V9	SERPINB7 SLC52A1 WDR76 ORC1 WDHD1	1.52e-04	170	132	5	a6cbe253bc60f5d5cb361c7e85ed9928a3155ec8
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBOAT1 GIMAP1 TBC1D10C CD247 KCNQ5	1.52e-04	170	132	5	bcbe5c44ef708c5f01dc7dd9aec7b436e1a62d56
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPEG TMEM88B HMCN2 KCNQ5 GRIN3A	1.57e-04	171	132	5	82de2885c8ce4fb7776da6a0207b3355c0910121
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPEG TMEM88B HMCN2 KCNQ5 GRIN3A	1.57e-04	171	132	5	09e653973962fb884878089d281f0947f7a285f6
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	CACNA1C SLC39A11 ITGA1 COL18A1 FRY	1.57e-04	171	132	5	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	facs-GAT-Fat-18m-Lymphocytic-T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA7 TBC1D10C CD247 FURIN TNF	1.61e-04	172	132	5	17a486c5d0430abb133eab9f087e2ef8b60f7d25
ToppCell	Basal_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	SERPINB7 ABCA13 KAT2A PKD1 GNAL	1.70e-04	174	132	5	a0060be3940043015dcc49a5157de5541aed24a1
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	POMT2 EML4 DDIT4L PHTF2 FRY	1.79e-04	176	132	5	437cfc5e06416bb0fc76d1f9dc106f74e279e880
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C DPY19L2 ITGA1 ABCC8 GLP1R	1.89e-04	178	132	5	066dbc4cc2083c549d98122ed44707127f34d582
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SERPINB7 ERO1B GIMAP1 TBC1D10C KCNQ5	1.89e-04	178	132	5	ba5a477257877f4a15a91c1762ffcc6f2e9f7357
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SERPINB7 ERO1B GIMAP1 TBC1D10C KCNQ5	1.89e-04	178	132	5	5634c1fbc817758092af4feafff94d107412d89b
ToppCell	facs-GAT-Fat-3m-Lymphocytic-B_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERO1B GIMAP1 DMXL1 TBC1D10C BFSP2	1.89e-04	178	132	5	5b6f7e8a930c239db1f31edfb61b2b9228d28663
ToppCell	Healthy_Control-Lymphoid-NK-NK\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	DPY19L2 ITGA1 CD247 KCNQ5 BFSP2	1.89e-04	178	132	5	71e99f143009b2d29cb47b96393b58b514c8cfc6
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-8\|TCGA-Kidney / Sample_Type by Project: Shred V9	SLC39A11 ABHD14B SLC22A18 SLC35F6 ACSF3	1.94e-04	179	132	5	8c6a84602b079bd357c66244371eb23dd9384918
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNDIG1L LINGO3 VWA7 KCNQ2 GNAL	1.94e-04	179	132	5	a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell	COVID-19-kidney-REN+Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C PHTF2 ITGA1 COL18A1 ABCC8	1.94e-04	179	132	5	342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WDR76 ORC1 WDHD1 PRKDC ESPL1	1.94e-04	179	132	5	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-Alox5+_Lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC39A11 TBC1D10C KCNQ5 GNAL BFSP2	1.99e-04	180	132	5	b28363626f4d2a552abde3434cc1df2e2121aba5
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-lymphocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC39A11 TBC1D10C KCNQ5 GNAL BFSP2	1.99e-04	180	132	5	67b062f2ef7e20f392e00c646f4985c415d40de9
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-T_mait\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TRIM46 EML4 DDIT4L VWA7 F7	1.99e-04	180	132	5	e53e9f3ebd48fb8237515e740ba5d9880ed6ade3
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-T_mait-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TRIM46 EML4 DDIT4L VWA7 F7	1.99e-04	180	132	5	9d18aa1044945fe6481ea3284037a777657fd837
ToppCell	normal_Lymph_Node-Myeloid_cells-Pleural_Mac\|normal_Lymph_Node / Location, Cell class and cell subclass	NLRP12 LGALS12 SLC7A7 EXOC3L1 CACNA2D3	2.04e-04	181	132	5	921e917f83105896ad8918dc134b871708024021
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VEZT GFRA2 TMEM88B COL18A1 CTNS	2.09e-04	182	132	5	6fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCell	Pericytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CACNA1C SPEG ITGA1 COL18A1 GLP1R	2.09e-04	182	132	5	46c213597445b1f4f09dc367f27702d24b201daf
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Th17\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGA1 TBC1D10C CD247 FURIN TNF	2.15e-04	183	132	5	1ee09af56dac121c841d869021ca625dd3336b84
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 F7 SLC2A2 SLC22A18 COL18A1	2.15e-04	183	132	5	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1\|TCGA-Thryoid / Sample_Type by Project: Shred V9	TRIM46 SERPINB7 COL11A1 WNT2 DCLK1	2.15e-04	183	132	5	06e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F COL11A1 ABCA13 SSPOP KCNQ2	2.20e-04	184	132	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPEG DDIT4L GFRA2 COL18A1 GLP1R	2.20e-04	184	132	5	89ae8bf1a6c2d355d279d23a5e24a08d9ec2334e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TBC1D10C CD247 GLP1R BFSP2 NCKAP1L	2.20e-04	184	132	5	6119140287ab4b88e41194bf8d6f77ae264b3b98
Disease	Polycystic Kidney, Autosomal Dominant	GANAB ALG9 PKD1	6.42e-06	9	127	3	C0085413
Disease	peak expiratory flow	COL11A1 EML4 ITGA1 FRY THADA KCNQ5 FIG4 PKD1 KCNQ2 CACNA2D3 SCAI	1.09e-05	498	127	11	EFO_0009718
Disease	Diabetes Mellitus, Non-Insulin-Dependent	ITGA1 SLC2A2 CAPN10 THADA ABCC8 GLP1R TNF	5.02e-05	221	127	7	C0011860
Disease	Autosomal dominant polycystic kidney disease	GANAB PKD1	5.50e-05	3	127	2	cv:C0085413
Disease	Cobblestone Lissencephaly	POMT2 TMTC3	5.50e-05	3	127	2	C0431376
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1F	1.10e-04	4	127	2	DOID:0060173 (implicated_via_orthology)
Disease	tax1-binding protein 3 measurement	NLRP12 CTNS	1.82e-04	5	127	2	EFO_0802120
Disease	Colorectal Neoplasms	ABCC3 ABCA13 LGR5 PGM1 ABCC8 TNF DCLK1	2.04e-04	277	127	7	C0009404
Disease	Bipolar Disorder	GABRG1 CACNA1C ABCA13 SLC1A6 KCNQ2 TNF GNAL GRIN3A DCLK1	2.30e-04	477	127	9	C0005586
Disease	heart conduction disease (implicated_via_orthology)	KCNQ5 KCNQ2 CACNA2D3	3.53e-04	32	127	3	DOID:10273 (implicated_via_orthology)
Disease	Polycystic kidney disease, type 2	GANAB PKD1	3.81e-04	7	127	2	C2751306
Disease	bilirubin metabolic disorder (biomarker_via_orthology)	ABCC3 F7	3.81e-04	7	127	2	DOID:2741 (biomarker_via_orthology)
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1C CACNA1F EML4	5.01e-04	36	127	3	DOID:11723 (implicated_via_orthology)
Disease	kidney disease (is_marker_for)	F7 TNF	5.06e-04	8	127	2	DOID:557 (is_marker_for)
Disease	Polycystic Kidney, Type 1 Autosomal Dominant Disease	GANAB PKD1	5.06e-04	8	127	2	C0887850
Disease	pregnanediol-3-glucuronide measurement	ABCC3 SLC22A25	5.06e-04	8	127	2	EFO_0800341
Disease	serum gamma-glutamyl transferase measurement	TRIM46 WSCD1 EML4 UGT1A6 SNX17 ITGA1 SLC2A2 PGM1 THADA PKD1 DDRGK1 KLHDC7A	6.00e-04	914	127	12	EFO_0004532
Disease	ulcerative colitis (biomarker_via_orthology)	COL18A1 TNF	6.49e-04	9	127	2	DOID:8577 (biomarker_via_orthology)
Disease	Anemia, Sickle Cell	CACNA1C TNF	8.09e-04	10	127	2	C0002895
Disease	Reactive hypoglycemia	CACNA1C TNF	8.09e-04	10	127	2	C0271710
Disease	Fasting Hypoglycemia	CACNA1C TNF	8.09e-04	10	127	2	C0271708
Disease	long QT syndrome (implicated_via_orthology)	KCNQ5 KCNQ2	8.09e-04	10	127	2	DOID:2843 (implicated_via_orthology)
Disease	Hypoglycemia	CACNA1C TNF	9.86e-04	11	127	2	C0020615
Disease	type 2 diabetes mellitus (implicated_via_orthology)	F7 SLC2A2 CAPN10 TNF	1.12e-03	105	127	4	DOID:9352 (implicated_via_orthology)
Disease	Herpes Zoster, response to tofacitinib	ACSF3 CACNA2D3	1.18e-03	12	127	2	EFO_0006510, EFO_0600024
Disease	coagulation factor X measurement	SNX17 F7	1.39e-03	13	127	2	EFO_0020265
Disease	Fulminant Hepatic Failure with Cerebral Edema	TNF PRKDC	1.39e-03	13	127	2	C0751197
Disease	Hepatic Stupor	TNF PRKDC	1.39e-03	13	127	2	C0751198
Disease	Hepatic Encephalopathy	TNF PRKDC	1.39e-03	13	127	2	C0019151
Disease	Hepatic Coma	TNF PRKDC	1.39e-03	13	127	2	C0019147
Disease	developmental and epileptic encephalopathy (implicated_via_orthology)	KCNQ5 KCNQ2	1.39e-03	13	127	2	DOID:0112202 (implicated_via_orthology)
Disease	Familial thoracic aortic aneurysm and aortic dissection	COL11A1 COL18A1 PKD1	1.56e-03	53	127	3	C4707243
Disease	Impaired cognition	CACNA1C EIF2B5	1.62e-03	14	127	2	C0338656
Disease	lymphocyte measurement	NLRP12 ITGA1 STT3A TMEM259	1.67e-03	117	127	4	EFO_0803546
Disease	diastolic blood pressure, body mass index	SLC39A11 GLP1R	2.12e-03	16	127	2	EFO_0004340, EFO_0006336
Disease	5-oxoproline measurement	GLP1R CCNI	2.12e-03	16	127	2	EFO_0010988
Disease	X-21441 measurement	ABCC3 UGT1A6	2.40e-03	17	127	2	EFO_0800814
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	ABCC3 TNF HADHA	2.80e-03	65	127	3	DOID:0080208 (biomarker_via_orthology)
Disease	response to methotrexate, neurotoxicity	DAB2IP MBOAT1	3.00e-03	19	127	2	EFO_0011057, GO_0031427
Disease	Severe Combined Immunodeficiency	CD247 PRKDC	3.32e-03	20	127	2	C0085110
Disease	Colorectal Carcinoma	ABCC3 ABCA13 LGR5 PGM1 CAPN10 KCNQ5 ABCC8 TNF DCLK1	3.42e-03	702	127	9	C0009402
Disease	Malignant Glioma	DMXL1 CLCN3 TNF	3.45e-03	70	127	3	C0555198
Disease	mixed gliomas	DMXL1 CLCN3 TNF	3.45e-03	70	127	3	C0259783
Disease	tissue factor measurement	UGT1A6 F7	3.66e-03	21	127	2	EFO_0010623
Disease	resting heart rate	CACNA1C SPEG SLC12A9 SUN2	3.99e-03	149	127	4	EFO_0004351
Disease	triacylglycerol 58:9 measurement	SLC39A11 NFKB2	4.01e-03	22	127	2	EFO_0010443
Disease	Bronchiectasis	NFKB2 TNF	4.01e-03	22	127	2	C0006267

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGTFLRSFSDALIRF	EXOC3L1	456	Q86VI1
FASLFSVLVRGSRAV	BUD23	146	O43709
FGLLSFSRSVALFRG	ALG9	421	Q9H6U8
ALLNAFGRLSTSIRD	ERO1B	441	Q86YB8
FALASSLLDRFLATV	CCNI	66	Q14094
RFRFLGSILVNLSSC	ABCA13	3416	Q86UQ4
SSGFRRTLILSSGFR	DDIT4L	161	Q96D03
VFTRALAFGDRIALV	ACSF3	46	Q4G176
FLLRVFSTGRVSLSA	CAPN10	481	Q9HC96
ARVTRRALGISSVFL	BFSP2	71	Q13515
LAGTINLSERRLFFT	DMXL1	1846	Q9Y485
AALLVGFILFLTRSR	DDRGK1	11	Q96HY6
GFILFLTRSRGRAAS	DDRGK1	16	Q96HY6
RLIFTDGSRIVFRLS	PGM1	491	P36871
FRSLFFGSILAPVRS	RAD9A	361	Q99638
VFGRSLLRSIFTVTR	KAT2A	316	Q92830
VVLFAALFAVIGRSS	ABCC3	1206	O15438
ARFSVLLLHGIRFSS	ABHD14B	31	Q96IU4
DSSRISITFFRLFRV	CACNA1F	1286	O60840
DISERLISASLFLRF	DAB2IP	511	Q5VWQ8
TSRSFAAFLASRLIG	MFSD10	136	Q14728
LAALGLSLFTRRAFS	SLC16A11	231	Q8NCK7
LSLFTRRAFSIFALG	SLC16A11	236	Q8NCK7
RRAFSIFALGTALVG	SLC16A11	241	Q8NCK7
FSALVIASAILLGFR	GLP1R	156	P43220
NLLGSATARAFLVVR	HMCN2	4376	Q8NDA2
FATSALRSLRFLQIL	KCNQ5	226	Q9NR82
TLILEFAALSRFTGA	EDEM3	231	Q9BZQ6
FRSFEALLADLTRTL	DCLK1	81	O15075
TLALTFLFQAREVRG	COL11A1	21	P12107
LRRFAFPLSLFQGSS	EIF2B5	221	Q13144
ALRRTFILSLGSVAF	MFSD6L	241	Q8IWD5
ASSGLRFVLASFALA	NAT14	51	Q8WUY8
VFATSALRSLRFLQI	KCNQ2	191	O43526
RLLAATFTLIGVSFF	KCNQ2	291	O43526
LALRRGSSFLILFLF	LGALS12	126	Q96DT0
FLFRLSATDLGLTVS	OR51F1	71	A6NGY5
RRRSAATFLLFVASL	PTGER1	66	P34995
VGLAGTFRAFLSSRL	COL18A1	1611	P39060
SVFLVEKAGRRSLFL	SLC2A2	356	P11168
LISLIRQRFGFSSGA	COIL	41	P38432
VSGALLSLHFLFVRR	NCKAP1L	201	P55160
DLVFVSRRAFAGLLA	LINGO3	161	P0C6S8
ARRFSSRTTLGIAVF	DPY19L2	101	Q6NUT2
LDSLRQISRSFFSGT	ITGA1	726	P56199
IFTLLSLFLVERAGR	SLC2A14	341	Q8TDB8
FLANTTFRGLSGSIR	GRIN3A	436	Q8TCU5
FFIRDLFLRISTATG	GNAL	326	P38405
SFLRAILAEFRRSGL	ORC1	776	Q13415
TLFLLAGFVSLFRIR	FZD5	416	Q13467
GFSLSIVRRFTLSVL	DYRK4	201	Q9NR20
SILGQRRFFSRLGAT	GIMAP1	46	Q8WWP7
ARIQRLFSFRALESG	ESPL1	1671	Q14674
FNATLFALVRTALRI	CACNA1C	1606	Q13936
VTSRLSDIFRLASIF	GFRA2	131	O00451
AFLFSPFLLRSQSRG	GABRG1	6	Q8N1C3
AFLGTRTGLSRINLF	CACNA2D3	726	Q8IZS8
LTALFLRVKFSRSAD	CD247	46	P20963
LSLAFDGDSFVRLRV	FCGBP	3386	Q9Y6R7
LIARRSSKFAGTRFL	FIG4	271	Q92562
TVFLVLQLRSGFSFR	FURIN	731	P09958
ASVTFNLFRLLTRDL	IFNL2	176	Q8IZJ0
RFLRRNAFILLTVSA	SLC1A6	51	P48664
LFLRGSLPTFRSSLF	GP1BA	596	P07359
FLTGILVTLAARAVR	MBOAT1	391	Q6ZNC8
ASFLSGLSASLLERR	TMEM259	551	Q4ZIN3
AIGILSRFSAFRILR	HADHA	6	P40939
IFVTGGSLRFLLFRF	KLHDC7A	636	Q5VTJ3
SLALITGLTFAIFRR	IZUMO1	301	Q8IYV9
FLVGTSRNFILRGTF	EML4	566	Q9HC35
RRKSVIGLSFDFVAL	CTNS	151	O60931
LVLGFGRTNSLVFRE	FRY	986	Q5TBA9
FLGRATTALLLSFLG	SLC22A11	386	Q9NSA0
SLRFLAGAATFSIIV	SLC22A25	201	Q6T423
RRAVFVASLVLTTGL	SLC22A31	156	A6NKX4
FLSVLGLLASRAVSA	SLC22A31	426	A6NKX4
AALVFVFSSGQRRIL	SLC39A11	26	Q8N1S5
ASTGRFTLNLSLLSR	CCDC103	171	Q8IW40
VLTTRFLFGLLSAER	NLRP6	541	P59044
SVFLLTLAALERGFS	LGR5	651	O75473
LRLSREAFLTTAEFG	PKD1	581	P98161
FLVVARAVGTFARAL	MTA3	196	Q9BTC8
GRRAAILLASALFTA	SLC2A13	146	Q96QE2
LFTRFAEAGRSTLRL	PIF1	76	Q9H611
FLLSKFRSATRGEII	SYTL5	186	Q8TDW5
FRLASTTSRRALFLA	SYNDIG1L	196	A6NDD5
TTSRRALFLATLAIA	SYNDIG1L	201	A6NDD5
VRLLARAFTLRTVGF	DROSHA	1121	Q9NRR4
SLTLFLLRFVTLGSE	PHTF2	676	Q8N3S3
RVSFLDAVSFRGLLE	TRIM46	701	Q7Z4K8
LFSALITRIFGVKRA	THADA	1256	Q6YHU6
AEGLSVRRASSAFLL	SSPOP	651	A2VEC9
LALVTLLSFATRFHR	POMT2	61	Q9UKY4
LLVARSFSGEVLFRS	TCP11X2	241	Q5H9J9
LEGRLVTKFSSVFLR	PRAMEF14	251	Q5SWL7
FLALRAQLTEFSRAL	PLEKHG4	531	Q58EX7
RTFSERTLAFVRFSL	F7	326	P08709
LLRRFSFSGNTLVSS	GANAB	861	Q14697
AAVLSFSTRLFAVLR	STT3A	26	P46977
FSTRLFAVLRFESVI	STT3A	31	P46977
LEGRLVAKFSSVFLR	PRAMEF1	251	O95521
RGARAALTLSFLAAL	SLC22A18	86	Q96BI1
LSSTFRILADLLGFA	ABCC8	301	Q09428
RSFFAALVAAFVLRS	CLCN3	351	P51790
IERFTRSSFLSGVGL	C10orf120	186	Q5SQS8
LLGSSETFNSFLRRA	SNX17	91	Q15036
LGPFVVRAFLRSSTS	MRPL1	286	Q9BYD6
LFGRVLLRSSRESAF	WNT2	96	P09544
RGIAARSDIGFLSLF	MINDY4	636	Q4G0A6
SLLDVFVLTRRFSSL	SUN2	196	Q9UH99
FLSLSREARGFLIKV	SPEG	1821	Q15772
TALLVTSAAAFRGLL	SLC52A1	201	Q9NWF4
LLQRSISSLLRFAAG	SPIDR	851	Q14159
FLSEGARVLFRVGLT	TBC1D10C	276	Q8IV04
AAATSALLLRLFTIG	WDHD1	546	O75717
ASIVAASRLFFVGSR	SLC7A7	326	Q9UM01
RASFLTFLLVSGSLA	SLC12A9	191	Q9BXP2
LGFSEFLLVSRTSSL	SLC35C2	256	Q9NQQ7
FLRLLLTRFIFCSAT	SCAI	536	Q8N9R8
SSLSLFAALALVRLG	SERPINB7	31	O75635
RALFSDRGSAALIVF	TMEM88B	96	A6NKF7
IFTGLFSVAFLGRRL	SLC35F6	126	Q8N357
LALQTSLVFSRDFGL	PRKDC	51	P78527
SLVFSRDFGLLVFVR	PRKDC	56	P78527
FFASLQLSESAARLR	WDR76	176	Q9H967
NFALIASLGLISFRS	ZNF792	46	Q3KQV3
RGFFILLTSSALLSE	TASOR2	126	Q5VWN6
RSGSSLTLASFILVF	AGPAT4	331	Q9NRZ5
FLRRTQFLLFFLTAA	WSCD1	11	Q658N2
RSFQRISAGVFFLAL	UGT1A6	6	P19224
QSSEFFRRLALLLST	VEZT	341	Q9HBM0
VGRAELLSSIFFLAA	TMTC3	141	Q6ZXV5
FTETGRRAILSLFVQ	UBR4	821	Q5T4S7
LASIQAFSLLRSRLG	VWA7	286	Q9Y334
SRKARSLVLFSLLFG	PRRT1B	231	A0A1B0GWB2
ISIFFRNGTGTALRI	SIGLEC14	241	Q08ET2
GSRRCLFLSLFSFLI	TNF	26	P01375
LLASFGDRVVRLSTA	JMJD8	86	Q96S16
SERSFLALTSRFLFG	NLRP12	551	P59046
TAGSVILRLSDSFFL	NAALADL1	571	Q9UQQ1
DLSIVRLRFSAFLRA	NFKB2	186	Q00653