Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium channel activity	CACNA1C CACNA1F RASA3 GRIN3A GRIN3B PKD1L3 ITPR3	2.03e-07	129	65	7	GO:0005262
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1C CACNA1F RASA3 GRIN3A GRIN3B PKD1L3 ITPR3	5.93e-07	151	65	7	GO:0015085
GeneOntologyMolecularFunction	gated channel activity	GABRB2 CACNA1C CACNA1F RASA3 ANO1 GRIN3A GRIN3B ITPR3	1.24e-05	334	65	8	GO:0022836
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1C CACNA1F RASA3 ANO1 GRIN3A GRIN3B PKD1L3 ITPR3	1.50e-05	343	65	8	GO:0005261
GeneOntologyMolecularFunction	monoatomic ion channel activity	GABRB2 CACNA1C CACNA1F RASA3 ANO1 GRIN3A GRIN3B PKD1L3 ITPR3	1.69e-05	459	65	9	GO:0005216
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	GABRB2 RASA3 ANO1 GRIN3A GRIN3B ITPR3	3.88e-05	193	65	6	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	GABRB2 RASA3 ANO1 GRIN3A GRIN3B ITPR3	4.35e-05	197	65	6	GO:0022834
GeneOntologyMolecularFunction	channel activity	GABRB2 CACNA1C CACNA1F RASA3 ANO1 GRIN3A GRIN3B PKD1L3 ITPR3	4.84e-05	525	65	9	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	GABRB2 CACNA1C CACNA1F RASA3 ANO1 GRIN3A GRIN3B PKD1L3 ITPR3	4.91e-05	526	65	9	GO:0022803
GeneOntologyMolecularFunction	NMDA glutamate receptor activity	GRIN3A GRIN3B	2.88e-04	8	65	2	GO:0004972
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1C CACNA1F ANO1 GRIN3A GRIN3B	3.16e-04	182	65	5	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1C CACNA1F ANO1 GRIN3A GRIN3B	3.32e-04	184	65	5	GO:0022832
GeneOntologyMolecularFunction	protein phosphatase 2A binding	CACNA1C HMGCR GRIN3A	3.45e-04	42	65	3	GO:0051721
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	GABRB2 CACNA1C CACNA1F RASA3 ANO1 GRIN3A GRIN3B PKD1L3 ITPR3	7.43e-04	758	65	9	GO:0015318
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1C CACNA1F RASA3 GRIN3A GRIN3B PKD1L3 ITPR3	7.71e-04	465	65	7	GO:0046873
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GABRB2 GRIN3A GRIN3B	8.50e-04	57	65	3	GO:1904315
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1C CACNA1F	9.26e-04	14	65	2	GO:0008331
GeneOntologyMolecularFunction	glycine binding	GRIN3A GRIN3B	9.26e-04	14	65	2	GO:0016594
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	GABRB2 GRIN3A GRIN3B	9.87e-04	60	65	3	GO:0099529
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	GABRB2 CACNA1C CACNA1F RASA3 ANO1 GRIN3A GRIN3B PKD1L3 ITPR3	1.02e-03	793	65	9	GO:0015075
GeneOntologyMolecularFunction	transmitter-gated channel activity	GABRB2 GRIN3A GRIN3B	1.25e-03	65	65	3	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	GABRB2 GRIN3A GRIN3B	1.25e-03	65	65	3	GO:0022824
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1C CACNA1F RASA3 ANO1 GRIN3A GRIN3B PKD1L3 ITPR3	1.36e-03	664	65	8	GO:0008324
GeneOntologyMolecularFunction	glutamate-gated receptor activity	GRIN3A GRIN3B	1.37e-03	17	65	2	GO:0004970
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RASA3 ITPR3	1.54e-03	18	65	2	GO:0015278
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	GABRB2 GRIN3A GRIN3B	1.88e-03	75	65	3	GO:0098960
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	GABRB2 GRIN3A GRIN3B	2.03e-03	77	65	3	GO:0005230
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GABRB2 GRIN3B	2.75e-03	24	65	2	GO:0099507
GeneOntologyMolecularFunction	transporter activity	GABRB2 CACNA1C CACNA1F RASA3 ATG2B ANO1 APOB GRIN3A GRIN3B PKD1L3 ITPR3	2.77e-03	1289	65	11	GO:0005215
GeneOntologyMolecularFunction	glutamate receptor activity	GRIN3A GRIN3B	3.47e-03	27	65	2	GO:0008066
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	GABRB2 CELSR1 CELSR2 OR6K2 OR10Q1 OR1A1 GRIN3A GRIN3B PKD1L3 OR2AJ1 EPHA5	4.02e-03	1353	65	11	GO:0004888
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1C CACNA1F RASA3 GRIN3A GRIN3B PKD1L3 ITPR3	4.19e-03	627	65	7	GO:0022890
GeneOntologyMolecularFunction	neurotransmitter receptor activity	GABRB2 GRIN3A GRIN3B	4.25e-03	100	65	3	GO:0030594
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	RASA3 ITPR3	4.57e-03	31	65	2	GO:0099604
GeneOntologyMolecularFunction	serine-type endopeptidase inhibitor activity	A2M SERPINA1 PZP	4.87e-03	105	65	3	GO:0004867
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	RASA3 ITPR3	5.16e-03	33	65	2	GO:0005217
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RASA2 RASA3 ARHGEF10 HMGCR DOCK6 ARAP2	6.06e-03	507	65	6	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RASA2 RASA3 ARHGEF10 HMGCR DOCK6 ARAP2	6.06e-03	507	65	6	GO:0030695
GeneOntologyBiologicalProcess	motor neuron migration	CELSR1 CELSR2 TBX20	1.32e-05	15	65	3	GO:0097475
GeneOntologyBiologicalProcess	response to abiotic stimulus	FANCD2 CYP1A1 CACNA1C BMP2 CACNA1F RASA3 VPS13A ANO1 HMGCR EIF2AK4 PRKDC PKD1L3 CBL ALKBH5 TG	1.63e-05	1361	65	15	GO:0009628
GeneOntologyCellularComponent	endoplasmic reticulum membrane	CYP1A1 MBTPS2 WFS1 TKT CTAGE1 ATG2B VPS13A ATL3 APOB HMGCR KLHL41 GRIN3A GRIN3B SPPL2C ITPR3	7.56e-06	1293	65	15	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	CYP1A1 MBTPS2 WFS1 TKT CTAGE1 ATG2B VPS13A ATL3 APOB HMGCR KLHL41 GRIN3A GRIN3B SPPL2C ITPR3	7.99e-06	1299	65	15	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	CYP1A1 MBTPS2 WFS1 TKT CTAGE1 ATG2B VPS13A ATL3 APOB HMGCR KLHL41 GRIN3A GRIN3B SPPL2C ITPR3	1.03e-05	1327	65	15	GO:0042175
GeneOntologyCellularComponent	monoatomic ion channel complex	GABRB2 CACNA1C CACNA1F ANO1 GRIN3A GRIN3B PKD1L3	1.69e-04	378	65	7	GO:0034702
GeneOntologyCellularComponent	NMDA selective glutamate receptor complex	GRIN3A GRIN3B	3.38e-04	9	65	2	GO:0017146
GeneOntologyCellularComponent	transmembrane transporter complex	GABRB2 CACNA1C CACNA1F ANO1 GRIN3A GRIN3B PKD1L3	1.17e-03	523	65	7	GO:1902495
MousePheno	abnormal social investigation	CACNA1C ARHGEF10 WFS1 VPS13A TBR1 GRIN3B ITPR3	2.32e-06	171	50	7	MP:0001360
MousePheno	abnormal social/conspecific interaction behavior	HEXB CACNA1C ARHGEF10 WFS1 TKT VPS13A TBR1 GRIN3B ITPR3	1.57e-05	421	50	9	MP:0002557
MousePheno	increased growth rate	EIF2AK4 ITPR3 TG	1.90e-05	15	50	3	MP:0002865
MousePheno	abnormal postnatal growth	FANCD2 WFS1 TKT ANO1 MUC5B KLHL41 EIF2AK4 PRKDC GRIN3B COLQ ITPR3 TG	6.32e-05	907	50	12	MP:0001731
Domain	TF_T-box	TBX18 TBR1 TBX20	2.52e-05	17	64	3	IPR001699
Domain	TBOX	TBX18 TBR1 TBX20	2.52e-05	17	64	3	SM00425
Domain	TF_T-box_CS	TBX18 TBR1 TBX20	2.52e-05	17	64	3	IPR018186
Domain	-	TBX18 TBR1 TBX20	2.52e-05	17	64	3	2.60.40.820
Domain	TBOX_3	TBX18 TBR1 TBX20	2.52e-05	17	64	3	PS50252
Domain	T-box	TBX18 TBR1 TBX20	2.52e-05	17	64	3	PF00907
Domain	TBOX_1	TBX18 TBR1 TBX20	2.52e-05	17	64	3	PS01283
Domain	TBOX_2	TBX18 TBR1 TBX20	2.52e-05	17	64	3	PS01264
Domain	Adaptor_Cbl_EF_hand-like	CBLC CBL	3.46e-05	3	64	2	IPR014741
Domain	Adaptor_Cbl_SH2-like	CBLC CBL	3.46e-05	3	64	2	IPR014742
Domain	Cbl_N2	CBLC CBL	3.46e-05	3	64	2	PF02761
Domain	Cbl_N3	CBLC CBL	3.46e-05	3	64	2	PF02762
Domain	CAC1F_C	CACNA1C CACNA1F	3.46e-05	3	64	2	IPR031688
Domain	Cbl_N	CBLC CBL	3.46e-05	3	64	2	PF02262
Domain	CAC1F_C	CACNA1C CACNA1F	3.46e-05	3	64	2	PF16885
Domain	Adaptor_Cbl_N_hlx	CBLC CBL	3.46e-05	3	64	2	IPR003153
Domain	CBL_PTB	CBLC CBL	3.46e-05	3	64	2	PS51506
Domain	Adaptor_Cbl	CBLC CBL	3.46e-05	3	64	2	IPR024162
Domain	Cbl_PTB	CBLC CBL	3.46e-05	3	64	2	IPR024159
Domain	-	CBLC CBL	3.46e-05	3	64	2	1.20.930.20
Domain	VDCC_L_a1su	CACNA1C CACNA1F	6.90e-05	4	64	2	IPR005446
Domain	ATG_C	ATG2B VPS13A	1.15e-04	5	64	2	PF09333
Domain	Autophagy-rel_C	ATG2B VPS13A	1.15e-04	5	64	2	IPR015412
Domain	WxxW_domain	MUC5B MUC5AC	1.72e-04	6	64	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC5AC	1.72e-04	6	64	2	PF13330
Domain	GPS	CELSR1 CELSR2 PKD1L3	2.13e-04	34	64	3	SM00303
Domain	GPS	CELSR1 CELSR2 PKD1L3	2.32e-04	35	64	3	PF01825
Domain	VDCC_a1su_IQ	CACNA1C CACNA1F	2.40e-04	7	64	2	IPR014873
Domain	GPHH	CACNA1C CACNA1F	2.40e-04	7	64	2	PF16905
Domain	GPHH_dom	CACNA1C CACNA1F	2.40e-04	7	64	2	IPR031649
Domain	Ca_chan_IQ	CACNA1C CACNA1F	2.40e-04	7	64	2	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1F	2.40e-04	7	64	2	PF08763
Domain	GPS	CELSR1 CELSR2 PKD1L3	2.53e-04	36	64	3	PS50221
Domain	GPS	CELSR1 CELSR2 PKD1L3	2.74e-04	37	64	3	IPR000203
Domain	VPS13_N	ATG2B VPS13A	3.19e-04	8	64	2	IPR026854
Domain	Chorein_N	ATG2B VPS13A	3.19e-04	8	64	2	PF12624
Domain	BTK	RASA2 RASA3	4.10e-04	9	64	2	SM00107
Domain	Znf_Btk_motif	RASA2 RASA3	4.10e-04	9	64	2	IPR001562
Domain	BTK	RASA2 RASA3	4.10e-04	9	64	2	PF00779
Domain	ZF_BTK	RASA2 RASA3	4.10e-04	9	64	2	PS51113
Domain	A2M_N	A2M PZP	5.11e-04	10	64	2	PF01835
Domain	A2M_N	A2M PZP	5.11e-04	10	64	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	A2M PZP	5.11e-04	10	64	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	A2M PZP	5.11e-04	10	64	2	PS00477
Domain	A2M	A2M PZP	5.11e-04	10	64	2	PF00207
Domain	A2M_N_2	A2M PZP	5.11e-04	10	64	2	IPR011625
Domain	A2M_comp	A2M PZP	5.11e-04	10	64	2	IPR011626
Domain	A2M_N_2	A2M PZP	5.11e-04	10	64	2	PF07703
Domain	VDCCAlpha1	CACNA1C CACNA1F	5.11e-04	10	64	2	IPR002077
Domain	A2M_recep	A2M PZP	5.11e-04	10	64	2	PF07677
Domain	A2M_comp	A2M PZP	5.11e-04	10	64	2	PF07678
Domain	Macroglobln_a2	A2M PZP	5.11e-04	10	64	2	IPR001599
Domain	GAIN_dom_N	CELSR1 CELSR2	6.23e-04	11	64	2	IPR032471
Domain	GAIN	CELSR1 CELSR2	6.23e-04	11	64	2	PF16489
Domain	TIL	MUC5B MUC5AC	7.46e-04	12	64	2	PF01826
Domain	C8	MUC5B MUC5AC	7.46e-04	12	64	2	PF08742
Domain	p53-like_TF_DNA-bd	TBX18 TBR1 TBX20	7.96e-04	53	64	3	IPR008967
Domain	Unchr_dom_Cys-rich	MUC5B MUC5AC	8.80e-04	13	64	2	IPR014853
Domain	C8	MUC5B MUC5AC	8.80e-04	13	64	2	SM00832
Domain	RasGAP	RASA2 RASA3	1.02e-03	14	64	2	SM00323
Domain	TIL_dom	MUC5B MUC5AC	1.02e-03	14	64	2	IPR002919
Domain	RasGAP_CS	RASA2 RASA3	1.02e-03	14	64	2	IPR023152
Domain	RasGAP	RASA2 RASA3	1.18e-03	15	64	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	RASA2 RASA3	1.18e-03	15	64	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	RASA2 RASA3	1.18e-03	15	64	2	PS50018
Domain	Glyco_hormone_CN	MUC5B MUC5AC	1.18e-03	15	64	2	IPR006208
Domain	Cys_knot	MUC5B MUC5AC	1.18e-03	15	64	2	PF00007
Domain	VWD	MUC5B MUC5AC	1.34e-03	16	64	2	SM00216
Domain	VWF_type-D	MUC5B MUC5AC	1.34e-03	16	64	2	IPR001846
Domain	-	RASA2 RASA3	1.34e-03	16	64	2	1.10.506.10
Domain	VWFD	MUC5B MUC5AC	1.34e-03	16	64	2	PS51233
Domain	VWD	MUC5B MUC5AC	1.34e-03	16	64	2	PF00094
Domain	Iontro_rcpt	GRIN3A GRIN3B	1.71e-03	18	64	2	IPR001320
Domain	Lig_chan-Glu_bd	GRIN3A GRIN3B	1.71e-03	18	64	2	PF10613
Domain	aa-tRNA-synth_II	EIF2AK4 NARS2	1.71e-03	18	64	2	IPR006195
Domain	Iono_rcpt_met	GRIN3A GRIN3B	1.71e-03	18	64	2	IPR001508
Domain	Glu/Gly-bd	GRIN3A GRIN3B	1.71e-03	18	64	2	IPR019594
Domain	RasGAP_dom	RASA2 RASA3	1.71e-03	18	64	2	IPR001936
Domain	Lig_chan-Glu_bd	GRIN3A GRIN3B	1.71e-03	18	64	2	SM00918
Domain	CTCK_1	MUC5B MUC5AC	1.71e-03	18	64	2	PS01185
Domain	Lig_chan	GRIN3A GRIN3B	1.71e-03	18	64	2	PF00060
Domain	PBPe	GRIN3A GRIN3B	1.71e-03	18	64	2	SM00079
Domain	Terpenoid_cyclase/PrenylTrfase	A2M PZP	1.71e-03	18	64	2	IPR008930
Domain	AA_TRNA_LIGASE_II	EIF2AK4 NARS2	1.71e-03	18	64	2	PS50862
Domain	VWC_out	MUC5B MUC5AC	1.90e-03	19	64	2	SM00215
Domain	CT	MUC5B MUC5AC	2.55e-03	22	64	2	SM00041
Domain	Ephrin_rec_like	EPHA5 TG	3.30e-03	25	64	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHA5 TG	3.30e-03	25	64	2	IPR011641
Domain	Cys_knot_C	MUC5B MUC5AC	3.30e-03	25	64	2	IPR006207
Domain	CTCK_2	MUC5B MUC5AC	3.30e-03	25	64	2	PS01225
Domain	HormR	CELSR1 CELSR2	3.30e-03	25	64	2	SM00008
Domain	Rho_GTPase_activation_prot	RASA2 RASA3 ARAP2	3.42e-03	88	64	3	IPR008936
Pubmed	Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors.	A2M SERPINA1 PZP	2.49e-08	4	65	3	1702714
Pubmed	Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study.	MUC5B MUC5AC SPPL2C	1.02e-06	11	65	3	24429156
Pubmed	Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice.	CELSR1 CELSR2 TBX20	1.35e-06	12	65	3	20631168
Pubmed	Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.	MUC5B APOB HMGCR MUC5AC	1.87e-06	47	65	4	11208732
Pubmed	Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease.	CELSR2 APOB HMGCR	3.43e-06	16	65	3	20691829
Pubmed	Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).	MUC5B MUC5AC	3.44e-06	2	65	2	7513696
Pubmed	Targeting an Achilles' heel of cancer with a WRN helicase inhibitor.	FANCD2 PRKDC	3.44e-06	2	65	2	24036544
Pubmed	The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.	MUC5B MUC5AC	3.44e-06	2	65	2	37146737
Pubmed	A meta-analysis of Italian and Estonian individuals shows an effect of common variants in HMGCR on blood apoB levels.	APOB HMGCR	3.44e-06	2	65	2	30191727
Pubmed	MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.	MUC5B MUC5AC	3.44e-06	2	65	2	14988081
Pubmed	Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.	MUC5B MUC5AC	3.44e-06	2	65	2	15563276
Pubmed	The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.	MUC5B MUC5AC	3.44e-06	2	65	2	17621824
Pubmed	CBL mutations in myeloproliferative neoplasms are also found in the gene's proline-rich domain and in patients with the V617FJAK2.	CBLC CBL	3.44e-06	2	65	2	22315494
Pubmed	Muc5b is required for airway defence.	MUC5B MUC5AC	3.44e-06	2	65	2	24317696
Pubmed	Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.	MUC5B MUC5AC	3.44e-06	2	65	2	22391959
Pubmed	Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.	MUC5B MUC5AC	3.44e-06	2	65	2	35776514
Pubmed	The ocular surface phenotype of Muc5ac and Muc5b null mice.	MUC5B MUC5AC	3.44e-06	2	65	2	24327612
Pubmed	TMEM16A chloride channel does not drive mucus production.	ANO1 MUC5AC	3.44e-06	2	65	2	31732694
Pubmed	A genetic polymorphism in a functional domain of human pregnancy zone protein: the bait region. Genomic structure of the bait domains of human pregnancy zone protein and alpha 2 macroglobulin.	A2M PZP	3.44e-06	2	65	2	1692292
Pubmed	Gel-forming mucins form distinct morphologic structures in airways.	MUC5B MUC5AC	3.44e-06	2	65	2	28607090
Pubmed	Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking.	CELSR1 CELSR2	3.44e-06	2	65	2	23292348
Pubmed	Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1IP4BP and GAP1m result from the GAP1IP4BP PH domain directing plasma membrane targeting.	RASA2 RASA3	3.44e-06	2	65	2	9382842
Pubmed	Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.	MUC5B MUC5AC	3.44e-06	2	65	2	31030254
Pubmed	The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.	MUC5B MUC5AC	3.44e-06	2	65	2	23527003
Pubmed	Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.	MUC5B MUC5AC	3.44e-06	2	65	2	16540890
Pubmed	Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.	MUC5B MUC5AC	3.44e-06	2	65	2	27845589
Pubmed	BMP2 Modified by the m6A Demethylation Enzyme ALKBH5 in the Ossification of the Ligamentum Flavum Through the AKT Signaling Pathway.	BMP2 ALKBH5	3.44e-06	2	65	2	31897529
Pubmed	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	MUC5B MUC5AC	3.44e-06	2	65	2	27435107
Pubmed	Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.	MUC5B MUC5AC	3.44e-06	2	65	2	26871672
Pubmed	Platelet alpha2-macroglobulin and alpha1-antitrypsin.	A2M SERPINA1	3.44e-06	2	65	2	59727
Pubmed	Differential binding properties of human pregnancy zone protein- and alpha2-macroglobulin-proteinase complexes to low-density lipoprotein receptor-related protein.	A2M PZP	3.44e-06	2	65	2	11811950
Pubmed	In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.	MUC5B MUC5AC	3.44e-06	2	65	2	11587997
Pubmed	Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.	MUC5B MUC5AC	3.44e-06	2	65	2	34656442
Pubmed	Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.	MUC5B MUC5AC	3.44e-06	2	65	2	34058148
Pubmed	C-Mannosylation of MUC5AC and MUC5B Cys subdomains.	MUC5B MUC5AC	3.44e-06	2	65	2	14718370
Pubmed	Nucleotide sequence, genomic organization, and chromosomal localization of genes encoding the human NMDA receptor subunits NR3A and NR3B.	GRIN3A GRIN3B	3.44e-06	2	65	2	11735224
Pubmed	Mucin production during prenatal and postnatal murine lung development.	MUC5B MUC5AC	3.44e-06	2	65	2	21653907
Pubmed	MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.	MUC5B MUC5AC	3.44e-06	2	65	2	36427316
Pubmed	Mucin deficiency causes functional and structural changes of the ocular surface.	MUC5B MUC5AC	3.44e-06	2	65	2	23272068
Pubmed	Loss of m6A demethylase ALKBH5 alleviates hypoxia-induced pulmonary arterial hypertension via inhibiting Cyp1a1 mRNA decay.	CYP1A1 ALKBH5	3.44e-06	2	65	2	38821243
Pubmed	Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.	MUC5B MUC5AC	3.44e-06	2	65	2	27729120
Pubmed	De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.	MUC5B MUC5AC	3.44e-06	2	65	2	36111525
Pubmed	Inhibition of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) stimulates osteoblastogenesis by potentiating bone morphogenetic protein 2 (BMP2) responses.	BMP2 PRKDC	3.44e-06	2	65	2	32686190
Pubmed	Genetic variation in N-methyl-D-aspartate receptor subunit NR3A but not NR3B influences susceptibility to Alzheimer's disease.	GRIN3A GRIN3B	3.44e-06	2	65	2	20016182
Pubmed	Fancd2 functions in a double strand break repair pathway that is distinct from non-homologous end joining.	FANCD2 PRKDC	3.44e-06	2	65	2	16135554
Pubmed	Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.	MUC5B MUC5AC	3.44e-06	2	65	2	32348677
Pubmed	Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.	MUC5B MUC5AC	3.44e-06	2	65	2	24332705
Pubmed	EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.	SERPINA1 WFS1 ATG2B VPS13A ATL3	9.36e-06	150	65	5	32423001
Pubmed	Interaction between human pancreatic elastase and plasma protease inhibitors.	A2M SERPINA1	1.03e-05	3	65	2	6153632
Pubmed	Radioimmunoassay of human pancreatic elastase 1. In vitro interaction of human pancreatic elastase 1 with serum protease inhibitors.	A2M SERPINA1	1.03e-05	3	65	2	6191979
Pubmed	High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.	MUC5B MUC5AC	1.03e-05	3	65	2	29286856
Pubmed	Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.	MUC5B MUC5AC	1.03e-05	3	65	2	36675209
Pubmed	C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus.	CBLC CBL	1.03e-05	3	65	2	11850825
Pubmed	Inactivation of c-Cbl or Cbl-b differentially affects signaling from the high affinity IgE receptor.	CBLC CBL	1.03e-05	3	65	2	15265912
Pubmed	Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.	MUC5B MUC5AC	1.03e-05	3	65	2	29802623
Pubmed	The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.	CELSR1 CELSR2	1.03e-05	3	65	2	11677057
Pubmed	Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.	MUC5B MUC5AC	1.03e-05	3	65	2	29604272
Pubmed	Loss of function Cbl-c mutations in solid tumors.	CBLC CBL	1.03e-05	3	65	2	31260484
Pubmed	Aquaporin 5 expression increases mucin production in lung adenocarcinoma.	MUC5B MUC5AC	1.03e-05	3	65	2	21455588
Pubmed	alpha2-macroglobulin- and murinoglobulin-1- deficient mice. A mouse model for acute pancreatitis.	A2M PZP	1.03e-05	3	65	2	10487856
Pubmed	Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.	MUC5B MUC5AC	1.03e-05	3	65	2	20422702
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC5B MUC5AC	1.03e-05	3	65	2	19718741
Pubmed	Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.	MUC5B MUC5AC	1.03e-05	3	65	2	27776277
Pubmed	Increased Trypanosoma cruzi invasion and heart fibrosis associated with high transforming growth factor beta levels in mice deficient in alpha(2)-macroglobulin.	A2M PZP	1.03e-05	3	65	2	12183561
Pubmed	Alpha-2 macroglobulin controls trophoblast positioning in mouse implantation sites.	A2M PZP	1.03e-05	3	65	2	14580373
Pubmed	Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.	MUC5B MUC5AC	1.03e-05	3	65	2	34158522
Pubmed	IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.	MUC5B MUC5AC	1.03e-05	3	65	2	19596978
Pubmed	Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.	MUC5B MUC5AC	1.03e-05	3	65	2	19556605
Pubmed	Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein.	A2M PZP	1.03e-05	3	65	2	8662763
Pubmed	Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.	CBLC CBL	1.03e-05	3	65	2	12226085
Pubmed	The human plasma proteome: a nonredundant list developed by combination of four separate sources.	A2M SERPINA1 APOB PZP TG	1.48e-05	165	65	5	14718574
Pubmed	Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2.	TBX18 BMP2 TBX20	1.97e-05	28	65	3	15901664
Pubmed	Critical role of phosphodiesterase 2A in mouse congenital heart defects.	TBX18 BMP2 TBX20	1.97e-05	28	65	3	29409032
Pubmed	ANO1 in intramuscular interstitial cells of Cajal plays a key role in the generation of slow waves and tone in the internal anal sphincter.	CACNA1C ANO1	2.06e-05	4	65	2	28054347
Pubmed	Interaction of matrix metalloproteinases-2 and -9 with pregnancy zone protein and alpha2-macroglobulin.	A2M PZP	2.06e-05	4	65	2	9344465
Pubmed	Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice.	A2M PZP	2.06e-05	4	65	2	27031383
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC5B MUC5AC	2.06e-05	4	65	2	25638393
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC5B MUC5AC	2.06e-05	4	65	2	22269464
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1C CACNA1F	2.06e-05	4	65	2	20937870
Pubmed	Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.	MUC5B MUC5AC	2.06e-05	4	65	2	18258655
Pubmed	Critical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesis.	RASA3 PRKDC	2.06e-05	4	65	2	22773809
Pubmed	The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.	CELSR1 CELSR2	2.06e-05	4	65	2	37224017
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5B MUC5AC	2.06e-05	4	65	2	23807779
Pubmed	Rapidly fatal myeloproliferative disorders in mice with deletion of Casitas B-cell lymphoma (Cbl) and Cbl-b in hematopoietic stem cells.	PRKDC CBL	2.06e-05	4	65	2	20805496
Pubmed	Morphological and molecular left-right asymmetries in the development of the proepicardium: a comparative analysis on mouse and chick embryos.	TBX18 BMP2	2.06e-05	4	65	2	17238175
Pubmed	ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.	MUC5B MUC5AC	2.06e-05	4	65	2	31582416
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5B MUC5AC	2.06e-05	4	65	2	17471237
Pubmed	MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium.	MUC5B MUC5AC	2.06e-05	4	65	2	21097527
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC5B MUC5AC	2.06e-05	4	65	2	14984930
Pubmed	TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.	MUC5B MUC5AC	2.06e-05	4	65	2	23249391
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC5B MUC5AC	2.06e-05	4	65	2	29869461
Pubmed	Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.	RASA3 ITPR3	2.06e-05	4	65	2	10828023
Pubmed	Enigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2A.	CBLC CBL	2.06e-05	4	65	2	24466333
Pubmed	NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons.	GRIN3A GRIN3B	2.06e-05	4	65	2	15813953
Pubmed	Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart.	TBX18 TBX20	2.06e-05	4	65	2	16677630
Pubmed	Cloning of the murine homolog of the leukemia-associated PML gene.	CYP1A1 CBL	2.06e-05	4	65	2	8563172
Pubmed	Developmental expression profiles of Celsr (Flamingo) genes in the mouse.	CELSR1 CELSR2	2.06e-05	4	65	2	11850187
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC5B MUC5AC	2.06e-05	4	65	2	12676567
Pubmed	Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.	CELSR2 APOB HMGCR	2.20e-05	29	65	3	20167577
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	FANCD2 TMEM156 CELSR2 WFS1 VPS13A APOB HMGCR PRKDC DOCK6 NARS2	2.62e-05	1061	65	10	33845483
Interaction	GNG8 interactions	A2M PRR4 SERPINA1 MUC5B APOB MUC5AC	2.57e-06	125	63	6	int:GNG8
Interaction	NUP210P1 interactions	CELSR1 CELSR2 VPS13A EIF2AK4	8.88e-06	42	63	4	int:NUP210P1
Interaction	KLK10 interactions	A2M SERPINA1 MUC5B APOB MUC5AC STOM	2.08e-05	180	63	6	int:KLK10
Interaction	ITLN2 interactions	A2M PRR4 SERPINA1 MUC5B	3.47e-05	59	63	4	int:ITLN2
Interaction	ADAMTS17 interactions	CELSR2 ATL3 N4BP2L2	3.72e-05	21	63	3	int:ADAMTS17
Cytoband	Ensembl 112 genes in cytogenetic band chr12p13	A2M CACNA1C PRR4 PZP	1.61e-03	353	65	4	chr12p13
Cytoband	4p14	TMEM156 ARAP2	1.64e-03	42	65	2	4p14
GeneFamily	T-boxes	TBX18 TBR1 TBX20	1.07e-05	18	44	3	766
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	1.73e-05	3	44	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	1.73e-05	3	44	2	1189
GeneFamily	Glutamate ionotropic receptor NMDA type subunits	GRIN3A GRIN3B	1.21e-04	7	44	2	1201
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	A2M PZP	2.06e-04	9	44	2	1234
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	RASA2 RASA3	2.57e-04	10	44	2	830
GeneFamily	CD molecules\|Mucins	MUC5B MUC5AC	1.18e-03	21	44	2	648
GeneFamily	Calcium voltage-gated channel subunits	CACNA1C CACNA1F	1.81e-03	26	44	2	253
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	ZBTB43 ZBTB8A KLHL41	4.22e-03	134	44	3	861
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASA2 RASA3 ARAP2	1.37e-02	206	44	3	682
Coexpression	GSE3982_BCELL_VS_NKCELL_DN	CACNA1F CELSR2 PZP COLQ MUC5AC EPHA5	8.72e-06	197	64	6	M5548
Coexpression	ONDER_CDH1_TARGETS_2_DN	CYP1A1 BMP2 SERPINA1 CELSR1 CELSR2 ANO1 CBLC ARAP2	1.94e-05	473	64	8	M4306
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#2_top-relative-expression-ranked_500	A2M TBX18 SERPINA1 APOB KLHL41 CCNB1IP1 PZP	5.89e-06	246	60	7	gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_500_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_top-relative-expression-ranked_200	TBX18 SERPINA1 APOB KLHL41 TBX20 PZP	6.40e-06	162	60	6	gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_top-relative-expression-ranked_500	A2M TBX18 SERPINA1 APOB KLHL41 CCNB1IP1 TBX20 PZP	1.79e-05	406	60	8	gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_top-relative-expression-ranked_1000	GABRB2 A2M TBX18 SERPINA1 APOB KLHL41 GRIN3A CCNB1IP1 TBX20 PZP	7.84e-05	805	60	10	gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#4_top-relative-expression-ranked_1000	A2M TBX18 SERPINA1 APOB KLHL41 CCNB1IP1 PZP	9.35e-05	379	60	7	gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_1000_k4
CoexpressionAtlas	DevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_1000	FANCD2 TBX18 SERPINA1 CELSR1 CELSR2 ANO1 ZBTB8A EIF2AK4 LDLRAD4 EPHA5	1.07e-04	836	60	10	gudmap_developingKidney_e15.5_Podocyte cells_1000
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_1000	GABRB2 A2M CACNA1C TBX18 SERPINA1 CELSR1 TNS2 EIF2AK4 GRIN3A DOCK6	1.29e-04	855	60	10	gudmap_developingKidney_e13.5_podocyte cells_1000
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEXB BMP2 ANO1 HMGCR ALKBH5 STOM	2.56e-07	180	65	6	a0faed4cf23f6d5e6e8f6b0284cea8a5bd0680a0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 A2M CACNA1F MUC5B APOB EPHA5	2.91e-07	184	65	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 A2M CACNA1F MUC5B APOB EPHA5	2.91e-07	184	65	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 A2M CACNA1F MUC5B APOB EPHA5	2.91e-07	184	65	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LV-17._Lymphocyte\|World / Chamber and Cluster_Paper	TMEM156 RASA2 PZP ARAP2 TG	5.44e-06	173	65	5	212f013ff761cbab24a537071739867c08c402a4
ToppCell	(03)_Secretory-(4)_1wkpi\|(03)_Secretory / shred by cell type and Timepoint	HEXB ANO1 MUC5AC STOM ITPR3	5.75e-06	175	65	5	06b52f85baa31b55bb31477244892b6da79fe2c9
ToppCell	LV-17._Lymphocyte\|LV / Chamber and Cluster_Paper	RASA2 RASA3 PZP ARAP2 TG	6.77e-06	181	65	5	81fafa69c8c240250a667a5f3b321e8be1b9a288
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_CD8_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	RASA2 ZNF827 N4BP2L2 LDLRAD4 ARAP2	8.35e-06	189	65	5	2c8a2fb76ea002bac554bc1c761ce960b5e116e1
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C ANO1 MUC5B STOM ARAP2	8.57e-06	190	65	5	1ab3f19f1ce9f58e5125135704d94655a2e330a0
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M VPS13A PZP STOM ARAP2	8.79e-06	191	65	5	4a29b7d5cd10e9077699d3aa76e3db6c4d5a0cf6
ToppCell	facs-Trachea-24m-Epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 CELSR2 CBLC MUC5B TG	9.24e-06	193	65	5	ec49a83b24371579d4ad46aad91c25115aa226f9
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	A2M N4BP2L2 APOB PZP	2.97e-05	121	65	4	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M WFS1 PZP TG	5.54e-05	142	65	4	61eefa32926a057e53747633bf4a81f09ea721c5
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX18 ANO1 TNS2 DOCK6	7.79e-05	155	65	4	ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX18 ANO1 TNS2 DOCK6	7.79e-05	155	65	4	0f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell-Peri\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX18 ANO1 TNS2 DOCK6	7.79e-05	155	65	4	d8b5145258f075b15080f8739f537f48dd22225e
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	A2M CACNA1C TBX18 TNS2	8.60e-05	159	65	4	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	A2M ANO1 GRIN3A TG	9.02e-05	161	65	4	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP2 ANO1 APOB STOM	9.24e-05	162	65	4	bc63a96ad3ba0b3433e3679d7a005f47709ff384
ToppCell	primary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX18 ANO1 TNS2 STOM	9.69e-05	164	65	4	9eed945e9b0c1ee5fc62724ac2bbbed4267b0678
ToppCell	primary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX18 ANO1 TNS2 STOM	9.69e-05	164	65	4	f510f20e37e31b486cdd0e3f597ce4ff00877c5d
ToppCell	Club_cells-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	CELSR1 ANO1 CBLC APOB	9.69e-05	164	65	4	4e25e6362ef793b08de2f4d1dccb6b1fc9c072a5
ToppCell	primary_visual_cortex-Non-neuronal-smooth_muscle_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TBX18 ANO1 TNS2 STOM	9.69e-05	164	65	4	5c932a462cbf81d029c8d11ec3aea3191529527b
ToppCell	control-Epithelial-Ionocyte\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GABRB2 GRIN3A DOCK6 EPHA5	9.92e-05	165	65	4	5cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCell	droplet-Fat-SCAT-30m-Lymphocytic-B_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL41 PKD1L3 ARAP2 TG	1.02e-04	166	65	4	4b31d2755108b2815316411a38bfb11fd30ef98a
ToppCell	NS-control-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GABRB2 GRIN3A DOCK6 EPHA5	1.02e-04	166	65	4	6d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP2 ANO1 DOCK6 STOM	1.06e-04	168	65	4	03896466698a79f7f1ad862cb7e05585260e2a5a
ToppCell	Ionocyte-iono-1\|World / Class top	HEXB BMP2 PZP EPHA5	1.09e-04	169	65	4	4b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	WFS1 ANO1 MUC5B MUC5AC	1.16e-04	172	65	4	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRB2 SERPINA1 MUC5B MUC5AC	1.30e-04	177	65	4	2af09028014f4ec3b7d2a4c286f1ae5e84a9f590
ToppCell	(5)_Glands_mucous\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	PRR4 SERPINA1 MUC5B MUC5AC	1.33e-04	178	65	4	f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCell	T_cells-GZMK+_CD8+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	A2M SERPINA1 PZP ARAP2	1.36e-04	179	65	4	798f208014f2229c597934775646ddbbacf94b69
ToppCell	(5)_Epithelial_cells-(5)_Glands_mucous\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	PRR4 SERPINA1 MUC5B MUC5AC	1.39e-04	180	65	4	a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M CACNA1C CELSR2 PZP	1.39e-04	180	65	4	557453b74d4a9cc95ed1c7b9a9a58e45eb02ed6a
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FANCD2 ZNF827 POLE2 TBX20	1.39e-04	180	65	4	87347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Trm/em_CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	A2M PZP STOM ARAP2	1.45e-04	182	65	4	f857b32de19240a8aca1685f7a78b4e53b04875c
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C RASA3 ANO1 LDLRAD4	1.45e-04	182	65	4	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	Adult-Mesenchymal-pericyte_cell-D122\|Adult / Lineage, Cell type, age group and donor	GABRB2 CACNA1C TNS2 DOCK6	1.48e-04	183	65	4	fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCell	CV-Healthy-7\|CV / Virus stimulation, Condition and Cluster	HEXB TMEM156 MBTPS2 RASA3	1.51e-04	184	65	4	0e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCell	Control-Epithelial-Goblet\|World / Disease state, Lineage and Cell class	CYP1A1 CBLC MUC5B MUC5AC	1.54e-04	185	65	4	9a793e6016295a63820e9d7563f195494ac692e7
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C RASA3 ANO1 DOCK6	1.54e-04	185	65	4	a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	A2M PRR4 HMGCR PRKDC	1.54e-04	185	65	4	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	CV-Healthy-7\|Healthy / Virus stimulation, Condition and Cluster	HEXB TMEM156 MBTPS2 RASA3	1.54e-04	185	65	4	1979d189c204f4c2893e3170a514ee7d5523406c
ToppCell	LA-07._Pericyte\|LA / Chamber and Cluster_Paper	A2M CACNA1C ANO1 DOCK6	1.54e-04	185	65	4	ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	A2M RASA2 RASA3 PZP	1.54e-04	185	65	4	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C ANO1 PZP LDLRAD4	1.57e-04	186	65	4	6add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRB2 A2M TNS2 DOCK6	1.57e-04	186	65	4	888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CACNA1F CBLC TBX20	1.60e-04	72	65	3	af3077e43d4b7abfd99146a71961142f946af136
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CACNA1F CBLC TBX20	1.60e-04	72	65	3	e13ee52d9a795cdc35068b0d8f8e6ed92adf8b66
ToppCell	Adult-Mesenchymal-pericyte_cell\|Adult / Lineage, Cell type, age group and donor	GABRB2 CACNA1C TNS2 DOCK6	1.60e-04	187	65	4	62759efb660179402fb574ce5701c89a2e17bcfe
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M PZP COLQ STOM	1.60e-04	187	65	4	f1ba41f2ec703251a81c46e08d45e70210f298e7
ToppCell	15-Trachea-Epithelial-Secretory_progenitor\|Trachea / Age, Tissue, Lineage and Cell class	GABRB2 BMP2 SERPINA1 MUC5B	1.60e-04	187	65	4	be9fce9e74b2f170a2067f1b31d802912a578329
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	A2M ANO1 TNS2 GRIN3A	1.60e-04	187	65	4	15d6e158562d7d85af3ceaf955439b379c8fce81
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	A2M ANO1 TNS2 GRIN3A	1.60e-04	187	65	4	f62074b631fd45ad299c69d71b09267b04d656ee
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M PZP STOM ARAP2	1.64e-04	188	65	4	f8e6247bedc0ba494c5bb551539cb8ba5a97f557
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	A2M ANO1 TNS2 GRIN3A	1.64e-04	188	65	4	32f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M PZP STOM ARAP2	1.64e-04	188	65	4	8155bc5476fc333bedcc78c5ddcc8e4912536caa
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMP2 TKT STOM ITPR3	1.64e-04	188	65	4	2b8d70f761eda5509f21845a87cdb3602a639dd7
ToppCell	facs-Kidney-nan-3m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C TBX18 ANO1 TBX20	1.67e-04	189	65	4	a5306561026e4dfcc39beeb785e5108ac595d136
ToppCell	facs-Kidney-nan-3m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C TBX18 ANO1 TBX20	1.67e-04	189	65	4	381058f55908f84375b54601d617389ef43ab855
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMP2 SERPINA1 COLQ ITPR3	1.67e-04	189	65	4	da014519d6eb21bc2dc2ed65eafe638b42a068ed
ToppCell	Striatum-Endothelial\|Striatum / BrainAtlas - Mouse McCarroll V32	TBX18 ANO1 TNS2 DOCK6	1.67e-04	189	65	4	95ee3b6d7fbbfcf91c780dfcd0926acec05f0a2d
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM\|lymph-node_spleen / Manually curated celltypes from each tissue	A2M PZP STOM ARAP2	1.67e-04	189	65	4	e8ff2c4fd2481bfbc99a5a6f02e0db8c995b3a23
ToppCell	facs-Kidney-nan-3m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C TBX18 ANO1 TBX20	1.67e-04	189	65	4	302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCell	COVID-19-T_cells-NK_cells\|COVID-19 / group, cell type (main and fine annotations)	RASA2 RASA3 PZP ARAP2	1.67e-04	189	65	4	b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M PZP COLQ STOM	1.71e-04	190	65	4	05e6af222d0ad97cb69f399a96c9038f9dd989b9
ToppCell	Fetal_29-31_weeks-Immune-T_lymphocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TMEM156 RASA2 RASA3 PZP	1.71e-04	190	65	4	2a8de1cf27a9ebc3825cf9e7a489ecd064dfc7f9
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GABRB2 CACNA1C TNS2 DOCK6	1.71e-04	190	65	4	4eb92aef1ee868f4537483d19014d947b7684612
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GABRB2 CACNA1C TNS2 DOCK6	1.71e-04	190	65	4	7be4341e2909101d756f14031c21e705eb45e69a
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Cd9_(Mural.Rgs5Acta2.Cd9)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CACNA1F CBLC TG	1.73e-04	74	65	3	7c7e45cf219b0be5cf0d0e5ea5daeb32284c8ccd
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Cd9_(Mural.Rgs5Acta2.Cd9)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CACNA1F CBLC TG	1.73e-04	74	65	3	6183baf43010268f54a6db9332296338f4f74009
ToppCell	COVID-19-lung-CD4+_Treg\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TMEM156 RASA3 LDLRAD4 ARAP2	1.74e-04	191	65	4	5a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRB2 A2M TNS2 DOCK6	1.74e-04	191	65	4	1626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRB2 A2M TNS2 DOCK6	1.74e-04	191	65	4	716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCell	COVID-19-T_cells\|COVID-19 / group, cell type (main and fine annotations)	TMEM156 RASA2 RASA3 ARAP2	1.74e-04	191	65	4	7f64add931b64b8d35836fa6bee9ebab593844d3
ToppCell	MatrixFB-Fibroblast-D_(Pericyte)\|MatrixFB / shred on cell class and cell subclass (v4)	BMP2 ANO1 STOM ARAP2	1.78e-04	192	65	4	630444302511f511ec6976bc045a3b4b9d8d4547
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SERPINA1 CBLC MUC5B MUC5AC	1.78e-04	192	65	4	612be3f861bd2f71a31c57f48c8b10930c3471ea
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SERPINA1 CBLC MUC5B MUC5AC	1.78e-04	192	65	4	f627a3f43e2340c8ba502211940171f25c7ff436
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRB2 A2M TNS2 STOM	1.81e-04	193	65	4	b2abe939027a69b60d83a28d4d4cc53ba1dee4c5
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRB2 A2M TNS2 STOM	1.81e-04	193	65	4	87ce81ff5b27d9c4300826d76ff5a62e9c408d5d
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRB2 A2M TNS2 STOM	1.81e-04	193	65	4	d75f334fe3d9f39ef02a5de0f8202f7a761a8fc8
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	A2M VPS13A N4BP2L2 ARAP2	1.81e-04	193	65	4	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRB2 A2M TNS2 STOM	1.81e-04	193	65	4	41ea268e7697101fe70d8ef1045f3a43b9311739
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RASA2 RASA3 PZP COLQ	1.81e-04	193	65	4	1cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M PZP STOM ARAP2	1.81e-04	193	65	4	523e2541f9f8d22b3c5263839a57cc1ab23d4963
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TMEM156 RASA2 LDLRAD4 ARAP2	1.85e-04	194	65	4	3d6f2d190dd50804afea299957cc44c2bb756134
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRB2 A2M TNS2 STOM	1.85e-04	194	65	4	3cffb5c58f6d5bd254f39ee9c41b7e1e4da0ff75
ToppCell	3'-Distal_airway-Mesenchymal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRB2 A2M TNS2 STOM	1.85e-04	194	65	4	f5e3e675187afb6efa774f2a8d685efcf813de82
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M PZP STOM ARAP2	1.88e-04	195	65	4	42382653e977714bff453bece26a6cd66ea2cc1f
ToppCell	COVID-19_Severe-CD8+_Tem\|COVID-19_Severe / Disease condition and Cell class	A2M PZP STOM ARAP2	1.88e-04	195	65	4	ff7ae62393e1c858a10592db8e6d9f36b8bae396
ToppCell	Posterior_cortex-Endothelial\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TBX18 TNS2 DOCK6 STOM	1.88e-04	195	65	4	988e3449691cc228cb55e5e30355136c97b12262
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M PZP STOM ARAP2	1.92e-04	196	65	4	17f17edadafdad9f24e88d708d7e1c765503131c
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	A2M N4BP2L2 CBL STOM	1.96e-04	197	65	4	66339b5aae3952f5c484c9dcb0cfb4fbd828d4cb
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	A2M VPS13A PZP ARAP2	1.96e-04	197	65	4	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M PZP STOM ARAP2	1.96e-04	197	65	4	ff34be81ee77efe60618641fa7c1084442b991d7
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M PZP STOM ARAP2	1.96e-04	197	65	4	a44501cac24c2f4a53b413e92bd060eed6514616
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PRR4 ANO1 MUC5B MUC5AC	1.96e-04	197	65	4	e2c820c4e4a6cd01ceb020473286e3f5d4e3718e
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M PZP STOM ARAP2	1.96e-04	197	65	4	35004d4728d33f15cc3be99a073b1ea965365c32
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M PZP STOM ARAP2	2.00e-04	198	65	4	a6b942fe850e287e1cb705684e29218072daf891
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	A2M VPS13A N4BP2L2 ARAP2	2.04e-04	199	65	4	f0b0097df0026496470a80d8cc9375ffd8389b00
Drug	gabapentin	GABRB2 CACNA1C CACNA1F GRIN3A GRIN3B PKD1L3 ITPR3	5.31e-07	169	65	7	CID000003446
Drug	riluzole	GABRB2 CACNA1C CACNA1F GRIN3A GRIN3B PKD1L3 ITPR3	6.47e-07	174	65	7	CID000005070
Drug	Iopromide [73334-07-3]; Up 200; 5uM; PC3; HT_HG-U133A	GABRB2 RASA3 ARHGEF10 ZBTB43 MUC5B TBR1 EPHA5	1.49e-06	197	65	7	4504_UP
Drug	CNS 1145	CACNA1C CACNA1F PKD1L3 ITPR3	2.33e-06	33	65	4	CID000190902
Drug	IHC-64	CACNA1C CACNA1F PKD1L3 ITPR3	2.33e-06	33	65	4	CID000162753
Drug	nimodipine	GABRB2 CACNA1C CACNA1F GRIN3B PKD1L3 ITPR3	3.65e-06	145	65	6	CID000004497
Drug	procaine	GABRB2 CACNA1C CACNA1F GRIN3A PKD1L3 ITPR3	4.97e-06	153	65	6	CID000004914
Drug	manidipine	CACNA1C CACNA1F HMGCR PKD1L3 ITPR3	7.71e-06	95	65	5	CID000004008
Drug	heptamolybdate	MBTPS2 RASA2 RASA3 APOB CBL	1.72e-05	112	65	5	CID005288823
Drug	baclofen	GABRB2 CACNA1C CACNA1F GRIN3B PKD1L3 ITPR3	1.76e-05	191	65	6	CID000002284
Drug	Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; PC3; HT_HG-U133A	CTAGE1 CBLC MUC5B MUC5AC EPHA5 ITPR3	1.87e-05	193	65	6	3708_UP
Drug	Cinildipine	CACNA1C CACNA1F PKD1L3 ITPR3	1.99e-05	56	65	4	CID000002752
Drug	lamotrigine	CACNA1C CACNA1F GRIN3B PKD1L3 ITPR3	2.04e-05	116	65	5	CID000003878
Drug	ethanol	GABRB2 CYP1A1 CACNA1C CACNA1F TKT POLE2 APOB GRIN3A GRIN3B MUC5AC ITPR3	2.26e-05	837	65	11	CID000000702
Drug	Dibenzo[e,l]pyrene	CYP1A1 TKT	2.40e-05	3	65	2	CID000009122
Drug	rosuvastatin	BMP2 SERPINA1 APOB HMGCR	2.45e-05	59	65	4	CID000446157
Drug	nilvadipine	CACNA1C CACNA1F PKD1L3 ITPR3	2.62e-05	60	65	4	CID000004494
Drug	IAA-94	CACNA1C CACNA1F PKD1L3 ITPR3	2.79e-05	61	65	4	CID000003667
Drug	pimozide	CACNA1C CACNA1F VPS13A PKD1L3 ITPR3	3.15e-05	127	65	5	CID000016362
Drug	lercanidipine	CACNA1C CACNA1F PKD1L3 ITPR3	3.17e-05	63	65	4	CID000065866
Drug	gallopamil	CACNA1C CACNA1F PKD1L3 ITPR3	4.05e-05	67	65	4	CID000001234
Drug	AC1L2AC7	CACNA1C CACNA1F PKD1L3 ITPR3	4.55e-05	69	65	4	CID000068733
Drug	Dibenzo[j,l]fluoranthene	CYP1A1 TKT	4.80e-05	4	65	2	CID006428082
Drug	benzo[b]perylene	CYP1A1 TKT	4.80e-05	4	65	2	CID000067455
Drug	Indeno[1,2,3-fg]naphthacene	CYP1A1 TKT	4.80e-05	4	65	2	CID000164559
Drug	Naphtho[2,3-e]pyrene	CYP1A1 TKT	4.80e-05	4	65	2	CID000009129
Drug	CAS 298-57-7	CACNA1C CACNA1F PKD1L3 ITPR3	5.68e-05	73	65	4	CID000002761
Drug	Dantrolene-13C3	CACNA1C CACNA1F GRIN3B PKD1L3 ITPR3	5.94e-05	145	65	5	CID000002951
Drug	ethosuximide	CACNA1C CACNA1F PKD1L3 ITPR3	5.99e-05	74	65	4	CID000003291
Drug	nisoldipine	CACNA1C CACNA1F PKD1L3 ITPR3	7.36e-05	78	65	4	CID000004499
Drug	N-cyclopentyl-N-cyclobutylformamide	CACNA1C CACNA1F PKD1L3 ITPR3	7.74e-05	79	65	4	CID005287890
Drug	Crilvastatine	APOB HMGCR	7.98e-05	5	65	2	CID000060724
Drug	dibenzo(a,i)pyrene	CYP1A1 TKT	7.98e-05	5	65	2	CID000009106
Drug	butylparaben	HEXB CYP1A1 CACNA1C CACNA1F GRIN3A	8.65e-05	157	65	5	ctd:C038091
Drug	isteropac	A2M SERPINA1	1.19e-04	6	65	2	CID000029182
Drug	1,2-benzoperylene	CYP1A1 TKT	1.19e-04	6	65	2	CID000115240
Drug	SCH 48461	APOB HMGCR	1.19e-04	6	65	2	CID000132832
Drug	Naphtho[2,3-a]pyrene	CYP1A1 TKT	1.19e-04	6	65	2	CID000009137
Drug	dicyclohexyl phthalate	A2M CYP1A1 APOB HMGCR GRIN3A TBX20 CBL ZP4 MUC5AC ITPR3	1.21e-04	836	65	10	ctd:C036042
Drug	felodipine	CYP1A1 CACNA1C CACNA1F PKD1L3 ITPR3	1.22e-04	169	65	5	CID000003333
Drug	HOCl	A2M HEXB SERPINA1 APOB NARS2	1.22e-04	169	65	5	CID000024341
Drug	thiazolidinedione	CYP1A1 APOB PKD1L3 CBL DOCK6 ITPR3	1.31e-04	274	65	6	CID000005437
Drug	PiMM	GABRB2 HEXB SERPINA1	1.36e-04	35	65	3	CID000110719
Drug	AC1L1KC5	CACNA1C CACNA1F SERPINA1 MBTPS2 WFS1 PKD1L3 ITPR3 TG	1.48e-04	541	65	8	CID000005428
Drug	Turpentine	A2M SERPINA1 PZP	1.61e-04	37	65	3	ctd:D014425
Drug	Tenocyclidine	GRIN3A GRIN3B	1.67e-04	7	65	2	DB01520
Drug	PNS-DKA	TKT MUC5AC	1.67e-04	7	65	2	CID009549211
Drug	Orphenadrine	GRIN3A GRIN3B	1.67e-04	7	65	2	DB01173
Drug	ammonium metavanadate	CYP1A1 HMGCR	1.67e-04	7	65	2	ctd:C101036
Drug	bitertanol	HEXB CYP1A1	1.67e-04	7	65	2	ctd:C083642
Drug	isotetrandrine	CACNA1C CACNA1F PKD1L3 ITPR3	1.72e-04	97	65	4	CID000005422
Drug	NSC7524	CACNA1C CACNA1F GRIN3B PKD1L3 ITPR3	1.73e-04	182	65	5	CID000005657
Drug	nitrendipine	CACNA1C CACNA1F PKD1L3 ITPR3	1.79e-04	98	65	4	CID000004507
Drug	JP8 aviation fuel	CYP1A1 SERPINA1 N4BP2L2 APOB HMGCR PRKDC ITPR3	1.89e-04	419	65	7	ctd:C098607
Drug	isradipine	CACNA1C CACNA1F PKD1L3 ITPR3	1.93e-04	100	65	4	CID000003784
Drug	acetone	CYP1A1 PRR4 TKT POLE2 APOB	1.96e-04	187	65	5	CID000000180
Drug	AC1L9GJJ	RASA2 RASA3 ITPR3	2.03e-04	40	65	3	CID000444570
Drug	cyclophorine	CACNA1C BMP2 CACNA1F APOB HMGCR PKD1L3 ITPR3	2.09e-04	426	65	7	CID000002909
Drug	NSC759576	CACNA1C CACNA1F APOB PKD1L3 ITPR3	2.17e-04	191	65	5	CID000003075
Drug	C12063	A2M HEXB SERPINA1 WFS1 APOB HMGCR TG	2.18e-04	429	65	7	CID005282055
Drug	nI-pI	A2M SERPINA1	2.22e-04	8	65	2	CID000125422
Drug	threosaminitol	HEXB MUC5AC	2.22e-04	8	65	2	CID000191652
Drug	Heptachlor Epoxide	CYP1A1 ATL3 HMGCR ITPR3	2.25e-04	104	65	4	ctd:D006534
Drug	GW8510; Up 200; 10uM; MCF7; HT_HG-U133A	GABRB2 CYP1A1 SERPINA1 MUC5B CBL	2.27e-04	193	65	5	7080_UP
Drug	Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A	GABRB2 CYP1A1 RASA3 MUC5B LDLRAD4	2.33e-04	194	65	5	3285_UP
Drug	loperamide	CACNA1C CACNA1F PKD1L3 ITPR3	2.33e-04	105	65	4	CID000003954
Drug	L 654969	BMP2 APOB HMGCR	2.35e-04	42	65	3	CID000005218
Drug	Niflumic Acid	GABRB2 ANO1 MUC5AC	2.35e-04	42	65	3	ctd:D009544
Drug	Piribedil hydrochloride [78213-63-5]; Down 200; 12uM; MCF7; HT_HG-U133A	GABRB2 CYP1A1 RASA2 ZBTB43 ITPR3	2.38e-04	195	65	5	3512_DN
Drug	Minocycline hydrochloride [13614-98-7]; Down 200; 8uM; PC3; HT_HG-U133A	CELSR2 VPS13A CBL DOCK6 EPHA5	2.38e-04	195	65	5	5077_DN
Drug	Meclozine dihydrochloride [1104-22-9]; Down 200; 8.6uM; PC3; HT_HG-U133A	SERPINA1 MBTPS2 ARHGEF10 PRKDC EPHA5	2.38e-04	195	65	5	4646_DN
Drug	Thiocolchicoside [602-41-5]; Up 200; 7uM; MCF7; HT_HG-U133A	CYP1A1 SERPINA1 MUC5B CBL MUC5AC	2.38e-04	195	65	5	2875_UP
Drug	Isosorbide dinitrate [87-33-2]; Up 200; 17uM; PC3; HT_HG-U133A	BMP2 RASA3 MUC5B DOCK6 ITPR3	2.44e-04	196	65	5	3720_UP
Drug	dimethylnitrosamine	A2M CYP1A1 TKT HMGCR KLHL41	2.44e-04	196	65	5	CID000006124
Drug	Zaprinast [37762-06-4]; Up 200; 14.8uM; MCF7; HT_HG-U133A	CYP1A1 PRR4 SERPINA1 ZBTB43 DOCK6	2.50e-04	197	65	5	5349_UP
Drug	Pentylenetetrazole [54-95-5]; Down 200; 29uM; PC3; HT_HG-U133A	MBTPS2 ZBTB43 VPS13A N4BP2L2 DOCK6	2.50e-04	197	65	5	2092_DN
Drug	2,4-Dichlorophenoxyacetic Acid	A2M CYP1A1 APOB HMGCR	2.50e-04	107	65	4	ctd:D015084
Drug	LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A	CELSR2 ZBTB43 VPS13A TNS2 ITPR3	2.56e-04	198	65	5	6976_UP
Drug	Cefotiam hydrochloride; Up 200; 7.2uM; MCF7; HT_HG-U133A	CYP1A1 SERPINA1 ZBTB43 TBR1 DOCK6	2.56e-04	198	65	5	5361_UP
Drug	Riboflavine [83-88-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A	CYP1A1 PRR4 RASA3 MUC5AC ITPR3	2.56e-04	198	65	5	2760_UP
Drug	Oxybenzone [131-57-7]; Up 200; 17.6uM; PC3; HT_HG-U133A	GABRB2 CYP1A1 PRR4 MBTPS2 MUC5AC	2.56e-04	198	65	5	6309_UP
Drug	Debrisoquin sulfate [581-88-4]; Up 200; 9uM; MCF7; HT_HG-U133A	CYP1A1 RASA3 ANO1 DOCK6 LDLRAD4	2.62e-04	199	65	5	3207_UP
Drug	scopolamine	A2M HMGCR GRIN3B PZP TG	2.68e-04	200	65	5	CID000005184
Drug	halothane	GABRB2 CYP1A1 CACNA1C CACNA1F PKD1L3 ITPR3	2.74e-04	314	65	6	CID000003562
Drug	Cinnarizine	CACNA1C CACNA1F	2.85e-04	9	65	2	DB00568
Drug	Nimodipine	CACNA1C CACNA1F	2.85e-04	9	65	2	DB00393
Drug	PD138142-15	CYP1A1 APOB	2.85e-04	9	65	2	CID003025787
Drug	Mevalonic Acid	CACNA1C BMP2 HMGCR MUC5AC	2.88e-04	111	65	4	ctd:D008798
Drug	clioquinol	A2M HMGCR PZP TG	3.19e-04	114	65	4	CID000002788
Drug	felbamate	GABRB2 CYP1A1 TKT	3.50e-04	48	65	3	ctd:C047360
Drug	Sialic acids	A2M HEXB SERPINA1 APOB MUC5AC TG	3.51e-04	329	65	6	CID000349960
Drug	AC1NBU2S	CACNA1C CACNA1F PKD1L3 ITPR3	3.52e-04	117	65	4	CID004473765
Drug	bitertanol	HEXB CYP1A1	3.56e-04	10	65	2	CID000091656
Drug	Chebi:29006	A2M PZP	3.56e-04	10	65	2	CID000130468
Drug	1,2-bis(2,4,6-tribromophenoxy)ethane	CYP1A1 SERPINA1	3.56e-04	10	65	2	ctd:C081014
Drug	2,6-TNS	A2M SERPINA1	3.56e-04	10	65	2	CID000082178
Disease	sleep duration, low density lipoprotein cholesterol measurement	CELSR2 ZNF827 CBLC APOB HMGCR PKD1L3	3.53e-08	91	61	6	EFO_0004611, EFO_0005271
Disease	LDL cholesterol change measurement	CELSR2 APOB PKD1L3	2.92e-07	7	61	3	EFO_0007804
Disease	liver fibrosis measurement	CELSR2 APOB HMGCR CBL ITPR3	9.78e-07	86	61	5	EFO_0010576
Disease	triglycerides to total lipids in large VLDL percentage	SERPINA1 CELSR2 APOB HMGCR	1.29e-06	39	61	4	EFO_0022332
Disease	cholesterol to total lipids in large VLDL percentage	SERPINA1 CELSR2 APOB HMGCR	2.31e-06	45	61	4	EFO_0022236
Disease	total lipids in lipoprotein particles measurement	CELSR2 APOB HMGCR DOCK6	3.00e-06	48	61	4	EFO_0022309
Disease	apolipoprotein B to apolipoprotein A1 ratio	CELSR2 APOB HMGCR DOCK6	3.27e-06	49	61	4	EFO_0021897
Disease	cholesteryl esters to total lipids in small VLDL percentage	SERPINA1 CELSR2 APOB HMGCR	3.27e-06	49	61	4	EFO_0022256
Disease	phospholipids:total lipids ratio, high density lipoprotein cholesterol measurement	SERPINA1 CELSR2 CTAGE1 APOB HMGCR PKD1L3 DOCK6	3.32e-06	307	61	7	EFO_0004612, EFO_0020946
Disease	free cholesterol in small LDL measurement	CELSR2 CBLC APOB HMGCR	4.49e-06	53	61	4	EFO_0022271
Disease	cholesteryl esters to total lipids in large VLDL percentage	SERPINA1 CELSR2 APOB HMGCR	5.60e-06	56	61	4	EFO_0022250
Disease	free cholesterol to total lipids in very large VLDL percentage	SERPINA1 CELSR2 APOB HMGCR	6.91e-06	59	61	4	EFO_0022289
Disease	esterified cholesterol measurement	CELSR2 CBLC APOB HMGCR DOCK6	6.95e-06	128	61	5	EFO_0008589
Disease	myocardial infarction	SERPINA1 CELSR2 N4BP2L2 APOB HMGCR PKD1L3 TBX20	7.83e-06	350	61	7	EFO_0000612
Disease	Vasculitis	SERPINA1 CBL	1.26e-05	3	61	2	C0042384
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	CELSR2 CTAGE1 CBLC APOB HMGCR	1.50e-05	150	61	5	EFO_0004611, EFO_0020947
Disease	low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	SERPINA1 CELSR2 APOB HMGCR DOCK6	1.65e-05	153	61	5	EFO_0004611, EFO_0020944
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1F	2.52e-05	4	61	2	DOID:0060173 (implicated_via_orthology)
Disease	Mood Disorders	GABRB2 CACNA1C SERPINA1 WFS1 VPS13A	2.59e-05	168	61	5	C0525045
Disease	diabetes mellitus (is_implicated_in)	CYP1A1 WFS1 HMGCR	2.96e-05	29	61	3	DOID:9351 (is_implicated_in)
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	SERPINA1 CELSR2 CBLC APOB HMGCR DOCK6	3.08e-05	291	61	6	EFO_0008317, EFO_0020946
Disease	intermediate density lipoprotein measurement	CELSR2 CBLC APOB HMGCR	3.24e-05	87	61	4	EFO_0008595
Disease	lipid measurement, lipoprotein measurement	CELSR2 APOB HMGCR DOCK6	3.70e-05	90	61	4	EFO_0004529, EFO_0004732
Disease	cholesteryl ester measurement, intermediate density lipoprotein measurement	CELSR2 CBLC APOB HMGCR	4.39e-05	94	61	4	EFO_0008595, EFO_0010351
Disease	HMG CoA reductase inhibitor use measurement	CELSR2 APOB HMGCR DOCK6 ITPR3	4.55e-05	189	61	5	EFO_0009932
Disease	lipid measurement, intermediate density lipoprotein measurement	CELSR2 CBLC APOB HMGCR	4.76e-05	96	61	4	EFO_0004529, EFO_0008595
Disease	total cholesterol measurement, intermediate density lipoprotein measurement	CELSR2 CBLC APOB HMGCR	5.37e-05	99	61	4	EFO_0004574, EFO_0008595
Disease	phospholipid measurement, intermediate density lipoprotein measurement	CELSR2 CBLC APOB HMGCR	5.37e-05	99	61	4	EFO_0004639, EFO_0008595
Disease	free cholesterol measurement, intermediate density lipoprotein measurement	CELSR2 CBLC APOB HMGCR	6.51e-05	104	61	4	EFO_0008591, EFO_0008595
Disease	familial hyperlipidemia	CELSR2 CBLC APOB HMGCR	7.01e-05	106	61	4	MONDO_0001336
Disease	apolipoprotein A 1 measurement, apolipoprotein B measurement	CELSR2 CBLC APOB HMGCR	7.27e-05	107	61	4	EFO_0004614, EFO_0004615
Disease	remnant cholesterol measurement	CELSR2 CBLC APOB HMGCR	7.54e-05	108	61	4	EFO_0010815
Disease	cholesterol in very small VLDL measurement	CELSR2 APOB HMGCR	7.86e-05	40	61	3	EFO_0022231
Disease	free cholesterol in medium LDL measurement	CELSR2 APOB HMGCR	7.86e-05	40	61	3	EFO_0022268
Disease	Liver carcinoma	FANCD2 A2M CYP1A1 SERPINA1 MBTPS2 HMGCR PZP	8.30e-05	507	61	7	C2239176
Disease	free cholesterol measurement	CELSR2 CBLC APOB HMGCR	8.99e-05	113	61	4	EFO_0008591
Disease	low density lipoprotein cholesterol measurement, lipid measurement	CELSR2 CBLC APOB HMGCR	9.31e-05	114	61	4	EFO_0004529, EFO_0004611
Disease	total cholesterol measurement, low density lipoprotein cholesterol measurement	CELSR2 CBLC APOB HMGCR	9.31e-05	114	61	4	EFO_0004574, EFO_0004611
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	SERPINA1 CELSR2 CBLC APOB HMGCR	9.73e-05	222	61	5	EFO_0008317, EFO_0020943
Disease	free cholesterol to total lipids in very small VLDL percentage	CELSR2 APOB HMGCR	9.78e-05	43	61	3	EFO_0022290
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	SERPINA1 CELSR2 CBLC APOB HMGCR	1.04e-04	225	61	5	EFO_0008317, EFO_0020947
Disease	concentration of large LDL particles measurement	CELSR2 APOB HMGCR	1.05e-04	44	61	3	EFO_0022160
Disease	Anxiety States, Neurotic	CACNA1C SERPINA1 TG	1.05e-04	44	61	3	C0376280
Disease	Anxiety neurosis (finding)	CACNA1C SERPINA1 TG	1.05e-04	44	61	3	C1279420
Disease	cholesterol in medium VLDL measurement	CELSR2 APOB HMGCR	1.05e-04	44	61	3	EFO_0022225
Disease	Anxiety Disorders	CACNA1C SERPINA1 TG	1.05e-04	44	61	3	C0003469
Disease	phospholipids:total lipids ratio	SERPINA1 CELSR2 APOB HMGCR DOCK6	1.08e-04	227	61	5	EFO_0020946
Disease	total lipids in very small VLDL measurement	CELSR2 APOB HMGCR	1.12e-04	45	61	3	EFO_0022156
Disease	low density lipoprotein cholesterol measurement, phospholipid measurement	CELSR2 CBLC APOB HMGCR	1.13e-04	120	61	4	EFO_0004611, EFO_0004639
Disease	esterified cholesterol measurement, intermediate density lipoprotein measurement	CELSR2 APOB	1.17e-04	8	61	2	EFO_0008589, EFO_0008595
Disease	common bile duct neoplasm (is_marker_for)	APOB MUC5AC	1.17e-04	8	61	2	DOID:4608 (is_marker_for)
Disease	total lipids in small LDL	CELSR2 APOB HMGCR	1.28e-04	47	61	3	EFO_0022168
Disease	free cholesterol in small VLDL measurement	CELSR2 APOB HMGCR	1.28e-04	47	61	3	EFO_0022272
Disease	free cholesterol in very small VLDL measurement	CELSR2 APOB HMGCR	1.28e-04	47	61	3	EFO_0022275
Disease	free cholesterol in medium VLDL measurement	CELSR2 APOB HMGCR	1.28e-04	47	61	3	EFO_0022269
Disease	cholesteryl ester measurement, low density lipoprotein cholesterol measurement	CELSR2 CBLC APOB HMGCR	1.37e-04	126	61	4	EFO_0004611, EFO_0010351
Disease	very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	SERPINA1 CELSR2 CBLC APOB HMGCR	1.37e-04	239	61	5	EFO_0008317, EFO_0020945
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	CELSR2 CTAGE1 CBLC APOB	1.41e-04	127	61	4	EFO_0008595, EFO_0020947
Disease	phospholipids in medium LDL measurement	CELSR2 APOB HMGCR	1.45e-04	49	61	3	EFO_0022183
Disease	cholesterol in medium LDL measurement	CELSR2 APOB HMGCR	1.45e-04	49	61	3	EFO_0022224
Disease	cholesterol in small LDL measurement	CELSR2 APOB HMGCR	1.45e-04	49	61	3	EFO_0022227
Disease	skin disease, response to cetuximab	ZNF827 EPHA5	1.50e-04	9	61	2	EFO_0000701, EFO_0007682
Disease	alpha-1-antitrypsin measurement	SERPINA1 CELSR2	1.50e-04	9	61	2	EFO_0008327
Disease	free cholesterol in LDL measurement	CELSR2 APOB HMGCR	1.54e-04	50	61	3	EFO_0022266
Disease	coronary artery disease	CYP1A1 SERPINA1 CELSR2 ZNF827 N4BP2L2 APOB HMGCR PKD1L3 TBX20 DOCK6	1.56e-04	1194	61	10	EFO_0001645
Disease	polyunsaturated fatty acid measurement	CELSR2 APOB HMGCR DOCK6	1.59e-04	131	61	4	EFO_0010733
Disease	free cholesterol in large LDL measurement	CELSR2 APOB HMGCR	1.63e-04	51	61	3	EFO_0022176
Disease	total cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement	CELSR2 APOB HMGCR	1.63e-04	51	61	3	EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Disease	phospholipids in very small VLDL measurement	CELSR2 APOB HMGCR	1.63e-04	51	61	3	EFO_0022300
Disease	phospholipids in medium VLDL measurement	CELSR2 APOB HMGCR	1.73e-04	52	61	3	EFO_0022154
Disease	phospholipids in IDL measurement	CELSR2 APOB HMGCR	1.73e-04	52	61	3	EFO_0022164
Disease	total lipids in medium LDL	CELSR2 APOB HMGCR	1.73e-04	52	61	3	EFO_0022180
Disease	total lipids in LDL measurement	CELSR2 APOB HMGCR	1.73e-04	52	61	3	EFO_0022308
Disease	phospholipids in large LDL measurement	CELSR2 APOB HMGCR	1.83e-04	53	61	3	EFO_0022174
Disease	triglycerides to total lipids in very large VLDL percentage	CELSR2 APOB HMGCR	1.83e-04	53	61	3	EFO_0022340
Disease	total phospholipids in lipoprotein particles measurement	CELSR2 APOB HMGCR	1.83e-04	53	61	3	EFO_0022315
Disease	cholesterol in small VLDL measurement	CELSR2 APOB HMGCR	1.83e-04	53	61	3	EFO_0022228
Disease	non-alcoholic fatty liver disease, cirrhosis of liver	TBX20 PZP ZP4	1.83e-04	53	61	3	EFO_0001422, EFO_0003095
Disease	Reactive hypoglycemia	CACNA1C SERPINA1	1.87e-04	10	61	2	C0271710
Disease	Fasting Hypoglycemia	CACNA1C SERPINA1	1.87e-04	10	61	2	C0271708
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	CELSR2 CBLC APOB HMGCR	1.89e-04	137	61	4	EFO_0004611, EFO_0008591
Disease	total lipids in medium VLDL	CELSR2 APOB HMGCR	1.93e-04	54	61	3	EFO_0022153
Disease	phospholipids in medium HDL measurement	CELSR2 APOB DOCK6	2.04e-04	55	61	3	EFO_0022295
Disease	free cholesterol to total lipids in large HDL percentage	CELSR2 APOB HMGCR	2.16e-04	56	61	3	EFO_0022279
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	SERPINA1 CELSR2 CBLC APOB HMGCR	2.18e-04	264	61	5	EFO_0008317, EFO_0020944
Disease	total lipids in large LDL	CELSR2 APOB HMGCR	2.27e-04	57	61	3	EFO_0022163
Disease	cholesterol in large LDL measurement	CELSR2 APOB HMGCR	2.27e-04	57	61	3	EFO_0021901
Disease	Hypoglycemia	CACNA1C SERPINA1	2.28e-04	11	61	2	C0020615
Disease	pulmonary fibrosis	MUC5B MUC5AC	2.28e-04	11	61	2	EFO_0009448
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	CELSR2 CBLC APOB HMGCR	2.29e-04	144	61	4	EFO_0004611, EFO_0020943
Disease	cholesterol in IDL measurement	CELSR2 APOB HMGCR	2.39e-04	58	61	3	EFO_0021899
Disease	total lipids in medium HDL measurement	CELSR2 APOB DOCK6	2.39e-04	58	61	3	EFO_0022310
Disease	phospholipids in LDL measurement	CELSR2 APOB HMGCR	2.39e-04	58	61	3	EFO_0022294
Disease	cholesterol in medium HDL measurement	CELSR2 APOB DOCK6	2.52e-04	59	61	3	EFO_0021903
Disease	phospholipids in VLDL measurement	CELSR2 APOB HMGCR	2.52e-04	59	61	3	EFO_0022301
Disease	phospholipids in small LDL measurement	CELSR2 APOB HMGCR	2.52e-04	59	61	3	EFO_0022297
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	SERPINA1 CELSR2 APOB HMGCR DOCK6	2.59e-04	274	61	5	EFO_0004530, EFO_0004612
Disease	phospholipids in small VLDL measurement	CELSR2 APOB HMGCR	2.65e-04	60	61	3	EFO_0022146
Disease	total lipids in IDL	CELSR2 APOB HMGCR	2.65e-04	60	61	3	EFO_0022161
Disease	total lipids in VLDL measurement	CELSR2 APOB HMGCR	2.65e-04	60	61	3	EFO_0022314

Protein segments in the cluster

Peptide	Gene	Start	Entry
KSGRPTFFTAVFNTF	ARHGEF10	821	O15013
TFFTAVFNTFTPAIK	ARHGEF10	826	O15013
IDQFLLTSFPTFTSV	CTAGE1	36	Q9HC47
VSIFEFDVFTRLFQP	CBLC	206	Q9ULV8
PSAAFFSETQRQFSR	EIF2AK4	571	Q9P2K8
STNIFFSPVSIATAF	SERPINA1	71	P01009
FERPIVSVSFFSDSA	ALKBH5	211	Q6P6C2
FSRRFEFETTPVFAA	EPHA5	551	P54756
TNEFRQRVPFSVFTT	POLE2	386	P56282
QSFEIITPYRSFSFT	ARAP2	646	Q8WZ64
EVTTRSFPPQSFVTF	CELSR1	1441	Q9NYQ6
QVTTRSFPAHSFITF	CELSR2	1366	Q9HCU4
RFFFNLSSIPTEEFI	BMP2	131	P12643
FRDQPVFFREFRFTS	ATG2B	1801	Q96BY7
SSTASLRAFQPFFVE	A2M	781	P01023
ITLFTPSSFFIVVQT	MUC5B	516	Q9HC84
ISSTASLRAFQPFFV	PZP	786	P20742
RTTIQEFIFSAFPYS	OR6K2	6	Q8NGY2
SFVFLRFFAVAVVSP	RASA2	506	Q15283
TAVSSFIFLRFFAPA	RASA3	476	Q14644
FILETFRHSSFVPFT	CYP1A1	371	P04798
VVLDTINAFFSSPFS	ITPR3	1471	Q14573
RSTFDTFPQALLTVF	CACNA1F	691	O60840
FFLSIVSQPTFINSV	COLQ	16	Q9Y215
GLFTIFSSFVFSTVV	HMGCR	96	P04035
IFALASRFQIPSVFT	KLHL41	106	O60662
SRIFFPVVFSFFNIV	GABRB2	491	P47870
SAANVTIFRPSTFFI	MUC5AC	521	P98088
TIFRPSTFFIIAQTS	MUC5AC	526	P98088
NAFVISFTSDFIPRL	ANO1	801	Q5XXA6
TARSQVIDFTSPFFS	GRIN3A	636	Q8TCU5
SLFFSAQPFEITAST	APOB	3036	P04114
RSTFDNFPQSLLTVF	CACNA1C	686	Q13936
FSGFRPATLTVTNFF	DOCK6	446	Q96HP0
NVFSTFRTPAVLFTG	ATL3	436	Q6DD88
VSITSFIPRFNFLSI	MBTPS2	421	O43462
ISVFEFDIFTRLFQP	CBL	236	P22681
SFLTTFFKEISEVFP	HEXB	331	P07686
STFPTLTRHTFVVFF	FANCD2	1221	Q9BXW9
SPTSVVFFLVLFVIF	OR2AJ1	21	Q8NGZ0
SYIRVFSTVFQVPST	OR1A1	216	Q9P1Q5
SEPTEFVFRAFTTAT	OR10Q1	11	Q8NGQ4
SARSQVVDFTSPFFS	GRIN3B	536	O60391
TSSFIVFFLFPRSVI	TMEM106A	106	Q96A25
VQTFTFPETQFIAVT	TBR1	356	Q16650
AFTQVFTFGPTFRAE	NARS2	231	Q96I59
FASDFFVVPRTVNVE	PKD1L3	671	Q7Z443
DVFFVFVTPFFTKTG	SPPL2C	386	Q8IUH8
AFSFLFTVITFPISI	STOM	36	P27105
SFFSFVSPSRELEQQ	CCNB1IP1	251	Q9NPC3
NSFRVEFPDFSSTIL	ZBTB43	6	O43298
SSLNFSFVTFLQPVR	TMEM156	51	Q8N614
SSFNITRIVTFTPFY	VPS13A	2301	Q96RL7
ATFQAFSPDTFTVIL	ZBTB8A	66	Q96BR9
RTVPFCSTFAAFFTR	TKT	381	P29401
FSFPETVFTTVTAYQ	TBX18	296	O95935
NRFLNTTFSFFPPFV	PRKDC	2841	P78527
RFPSVSLQEASSFFQ	PRR4	106	Q16378
RTTTSPFFSEDTFRQ	ZNF827	756	Q17R98
FRTFIFPETVFTAVT	TBX20	251	Q9UMR3
DAFVTFSSFQRRFPE	TG	216	P01266
RFPFQASVEFVFSSS	TNS2	411	Q63HR2
RFSIFTFSFVNPTVE	ZP4	416	Q12836
TFISDSVPNFTELFS	TMEM145	446	Q8NBT3
SVFFVIFSFPIASKD	WFS1	411	O76024
FTAPSFIQRDRFSRF	LDLRAD4	141	O15165
QVIPTFCDTSFTSFR	N4BP2L2	251	Q92802