Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein serine kinase activity	SMG1 MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 CDK10 PRKAA1 MAP3K10 CDK1 CDK4 DYRK3 CDK6	9.59e-07	363	155	14	GO:0106310
GeneOntologyMolecularFunction	cyclin-dependent protein serine/threonine kinase activity	CDK12 CDK10 CDK1 CDK4 CDK6	3.22e-06	30	155	5	GO:0004693
GeneOntologyMolecularFunction	cyclin-dependent protein kinase activity	CDK12 CDK10 CDK1 CDK4 CDK6	3.22e-06	30	155	5	GO:0097472
GeneOntologyMolecularFunction	protein kinase activity	SMG1 MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 RET CDK10 EFNB3 PRKAA1 MAP3K10 CDK1 EPHA1 CDK4 DYRK3 CDK6	4.41e-06	600	155	17	GO:0004672
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	SMG1 MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 RET CDK10 EFNB3 PIK3C2B PRKAA1 MAP3K10 CDK1 EPHA1 CDK4 DYRK3 CDK6	1.03e-05	709	155	18	GO:0016773
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	SMG1 MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 CDK10 PRKAA1 MAP3K10 CDK1 CDK4 DYRK3 CDK6	1.04e-05	446	155	14	GO:0004674
GeneOntologyMolecularFunction	kinase activity	SMG1 MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 RET CDK10 EFNB3 PIK3C2B PRKAA1 MAP3K10 CDK1 EPHA1 CDK4 DYRK3 CDK6	2.78e-05	764	155	18	GO:0016301
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	SMG1 MAP2K4 PIM2 MARK1 CDK12 MAP3K8 GNPTAB PAK5 RET CDK10 EFNB3 PIK3C2B PRKAA1 MAP3K10 CDK1 EPHA1 CDK4 DYRK3 CDK6	1.24e-04	938	155	19	GO:0016772
GeneOntologyMolecularFunction	cyclin binding	CDK12 CDK1 CDK4 CDK6	1.52e-04	35	155	4	GO:0030332
GeneOntologyMolecularFunction	heparan sulfate 6-O-sulfotransferase activity	HS6ST2 HS6ST1	1.79e-04	3	155	2	GO:0017095
GeneOntologyMolecularFunction	exogenous lipid antigen binding	CD1A CD1B	5.90e-04	5	155	2	GO:0030884
GeneOntologyMolecularFunction	endogenous lipid antigen binding	CD1A CD1B	5.90e-04	5	155	2	GO:0030883
GeneOntologyMolecularFunction	lipid antigen binding	CD1A CD1B	8.80e-04	6	155	2	GO:0030882
GeneOntologyBiologicalProcess	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	CD1A CD1B AP3D1	1.34e-05	7	152	3	GO:0048007
GeneOntologyBiologicalProcess	antigen processing and presentation of lipid antigen via MHC class Ib	CD1A CD1B AP3D1	1.34e-05	7	152	3	GO:0048003
GeneOntologyCellularComponent	cyclin-dependent protein kinase holoenzyme complex	CDK12 CDK10 CCNA2 CDK1 CDK4 CDK6	5.76e-06	61	154	6	GO:0000307
GeneOntologyCellularComponent	protein kinase complex	CDK12 CDK10 CCNA2 PRKAA1 CDK1 LAS1L CDK4 CDK6	3.87e-05	170	154	8	GO:1902911
GeneOntologyCellularComponent	female pronucleus	SLC2A1 CCNA2 TET3	4.53e-05	10	154	3	GO:0001939
GeneOntologyCellularComponent	cyclin A2-CDK1 complex	CCNA2 CDK1	5.39e-05	2	154	2	GO:0097122
GeneOntologyCellularComponent	basal plasma membrane	ITGA3 SLC2A1 NOD1 SLC22A4 PKD1 LRP1 KCNN4 GM2A SLC41A1 SLC4A9	3.04e-04	354	154	10	GO:0009925
GeneOntologyCellularComponent	apical part of cell	FN1 TMEM114 LCT SLC2A1 NOD1 SLC22A4 PRKAA1 ASPM PKHD1 LRP1 KCNN4 GM2A SLC4A9	4.52e-04	592	154	13	GO:0045177
GeneOntologyCellularComponent	basal part of cell	ITGA3 SLC2A1 NOD1 SLC22A4 PKD1 LRP1 KCNN4 GM2A SLC41A1 SLC4A9	5.08e-04	378	154	10	GO:0045178
GeneOntologyCellularComponent	basolateral plasma membrane	ITGA3 SLC2A1 NOD1 PKD1 LRP1 KCNN4 GM2A SLC41A1 SLC4A9	6.28e-04	320	154	9	GO:0016323
GeneOntologyCellularComponent	transferase complex, transferring phosphorus-containing groups	CDK12 CDK10 CCNA2 PIK3C2B PRKAA1 CDK1 LAS1L CDK4 CDK6	8.68e-04	335	154	9	GO:0061695
GeneOntologyCellularComponent	apical plasma membrane	FN1 TMEM114 LCT SLC2A1 NOD1 SLC22A4 PRKAA1 ASPM PKHD1 KCNN4 GM2A	9.91e-04	487	154	11	GO:0016324
GeneOntologyCellularComponent	serine/threonine protein kinase complex	CDK12 CDK10 CCNA2 CDK1 CDK4 CDK6	1.10e-03	157	154	6	GO:1902554
GeneOntologyCellularComponent	pronucleus	SLC2A1 CCNA2 TET3	1.12e-03	28	154	3	GO:0045120
GeneOntologyCellularComponent	male pronucleus	CCNA2 TET3	1.47e-03	8	154	2	GO:0001940
GeneOntologyCellularComponent	dendrite	CACNA1C MAP2K4 HDAC6 PNMT MARK1 RGS11 RET GRM3 PTPRZ1 KCNJ6 PRKAA1 NEURL1 LRP1 BAIAP2 MMP3	1.71e-03	858	154	15	GO:0030425
GeneOntologyCellularComponent	dendritic tree	CACNA1C MAP2K4 HDAC6 PNMT MARK1 RGS11 RET GRM3 PTPRZ1 KCNJ6 PRKAA1 NEURL1 LRP1 BAIAP2 MMP3	1.75e-03	860	154	15	GO:0097447
HumanPheno	Abnormality of globe location or size	POMT2 CACNA1C ERCC1 DEAF1 HDAC6 FN1 STAG1 MARS1 HS6ST2 GNPTAB SPTBN1 BCORL1 NUP88 SMPD4 ITGA3 RET NSMCE3 CDK10 SLC2A1 SLC2A10 MEGF8 TENM3 CCBE1 FANCI HS6ST1 KCNJ6 PPP1R15B SCN4A ASPM KIF14 LAS1L CPLANE1 TMCO1 AP3D1	4.07e-06	1246	68	34	HP:0000489
MousePheno	abnormal kidney collecting duct morphology	STAG1 ITGA3 RET NPHP3 PKD1 PKHD1	6.11e-06	53	121	6	MP:0004754
MousePheno	abnormal renal tubule morphology	ERCC1 SGSH ITGA3 RET CDK10 NPHP3 PKD1 PKHD1 CPLANE1 AP3D1	2.75e-05	227	121	10	MP:0002703
MousePheno	abnormal kidney epithelial cell primary cilium morphology	NPHP3 PKD1 PKHD1 CPLANE1	4.16e-05	23	121	4	MP:0011065
Domain	Kinase-like_dom	SMG1 MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 RET CDK10 PIK3C2B PRKAA1 MAP3K10 CDK1 EPHA1 CDK4 DYRK3 CDK6	2.51e-06	542	154	17	IPR011009
Domain	Protein_kinase_ATP_BS	MAP2K4 PIM2 MARK1 CDK12 PAK5 RET CDK10 PRKAA1 MAP3K10 CDK1 EPHA1 CDK4 DYRK3 CDK6	3.18e-06	379	154	14	IPR017441
Domain	PROTEIN_KINASE_ATP	MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 RET CDK10 PRKAA1 MAP3K10 CDK1 EPHA1 CDK4 DYRK3 CDK6	6.21e-06	459	154	15	PS00107
Domain	Ser/Thr_kinase_AS	MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 CDK10 PRKAA1 MAP3K10 CDK1 CDK4 DYRK3 CDK6	8.46e-06	357	154	13	IPR008271
Domain	S_TKc	MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 CDK10 PRKAA1 MAP3K10 CDK1 CDK4 DYRK3 CDK6	8.98e-06	359	154	13	SM00220
Domain	PROTEIN_KINASE_ST	MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 CDK10 PRKAA1 MAP3K10 CDK1 CDK4 DYRK3 CDK6	9.82e-06	362	154	13	PS00108
Domain	Prot_kinase_dom	MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 RET CDK10 PRKAA1 MAP3K10 CDK1 EPHA1 CDK4 DYRK3 CDK6	1.32e-05	489	154	15	IPR000719
Domain	PROTEIN_KINASE_DOM	MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 RET CDK10 PRKAA1 MAP3K10 CDK1 EPHA1 CDK4 DYRK3 CDK6	1.45e-05	493	154	15	PS50011
Domain	Pkinase	MAP2K4 PIM2 MARK1 CDK12 MAP3K8 PAK5 CDK10 PRKAA1 MAP3K10 CDK1 CDK4 DYRK3 CDK6	1.69e-05	381	154	13	PF00069
Domain	ARM-type_fold	SMG1 VPS11 STAG1 DOCK8 HEATR4 WDFY4 URB1 PIK3C2B ASPM TARBP1 AP3D1	1.20e-04	339	154	11	IPR016024
Domain	Renal_dipep_fam	DPEP2 DPEP3	2.02e-04	3	154	2	IPR008257
Domain	Peptidase_M19	DPEP2 DPEP3	2.02e-04	3	154	2	PF01244
Domain	Dipep_AS	DPEP2 DPEP3	2.02e-04	3	154	2	IPR000180
Domain	RENAL_DIPEPTIDASE_1	DPEP2 DPEP3	2.02e-04	3	154	2	PS00869
Domain	Heparan_SO4-6-sulfoTrfase	HS6ST2 HS6ST1	2.02e-04	3	154	2	IPR010635
Domain	RENAL_DIPEPTIDASE_2	DPEP2 DPEP3	2.02e-04	3	154	2	PS51365
Domain	ARM-like	SMG1 STAG1 DOCK8 HEATR4 PPP4R1L WDFY4 ASPM TARBP1 AP3D1	4.12e-04	270	154	9	IPR011989
Pubmed	Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation.	CCNA2 CDK1 CDK4 CDK6	4.82e-08	9	156	4	16678773
Pubmed	A CRISPR knockout negative screen reveals synergy between CDKs inhibitor and metformin in the treatment of human cancer in vitro and in vivo.	CDK1 CDK4 CDK6	8.85e-08	3	156	3	32811807
Pubmed	Specific regulation of E2F family members by cyclin-dependent kinases.	CCNA2 CDK1 CDK4 CDK6	1.25e-07	11	156	4	9199321
Pubmed	Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6.	CCNA2 CDK1 CDK4 CDK6	2.70e-07	13	156	4	7739547
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	PIM2 PNMT CDK12 MAP3K8 NPEPPS RET PIK3C2B PTPRZ1 PRKAA1 MAP3K10	5.33e-07	276	156	10	28319085
Pubmed	Mouse development and cell proliferation in the absence of D-cyclins.	CCNA2 CDK1 CDK4 CDK6	6.80e-07	16	156	4	15315760
Pubmed	Targeting cyclin-dependent kinase 1 (CDK1) but not CDK4/6 or CDK2 is selectively lethal to MYC-dependent human breast cancer cells.	CDK1 CDK4 CDK6	8.79e-07	5	156	3	24444383
Pubmed	S10 phosphorylation of p27 mediates atRA induced growth arrest in ovarian carcinoma cell lines.	CDK1 CDK4 CDK6	8.79e-07	5	156	3	18615582
Pubmed	Cdk1 is sufficient to drive the mammalian cell cycle.	CDK1 CDK4 CDK6	8.79e-07	5	156	3	17700700
Pubmed	Formation of p27-CDK complexes during the human mitotic cell cycle.	CCNA2 CDK4 CDK6	1.75e-06	6	156	3	8822197
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CRYBG2 ARSJ CDK12 ELP6 ATG2A ITGA3 SLC2A1 URB1 MEGF8 SH3TC1 PIK3C2B FANCI PPP1R15B PKD1 ZFYVE26 ZNF324B GGA1 AP3D1	2.58e-06	1105	156	18	35748872
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	FN1 ITGA2B MEGF8 PTPRZ1 DPEP2 SUSD2 LRP1 LILRB5 GAA	2.65e-06	257	156	9	16335952
Pubmed	Distinct phosphorylation events regulate p130- and p107-mediated repression of E2F-4.	CCNA2 CDK4 CDK6	3.06e-06	7	156	3	12006580
Pubmed	Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites.	CCNA2 CDK1 CDK4	3.06e-06	7	156	3	8626527
Pubmed	Tob2, a novel anti-proliferative Tob/BTG1 family member, associates with a component of the CCR4 transcriptional regulatory complex capable of binding cyclin-dependent kinases.	CDK1 CDK4 CDK6	3.06e-06	7	156	3	10602502
Pubmed	Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit.	CCNA2 CDK1 CDK4 CDK6	4.58e-06	25	156	4	28923932
Pubmed	Differential modulation of G1-S-phase cyclin-dependent kinase 2/cyclin complexes occurs during the acquisition of a polyploid DNA content.	CCNA2 CDK4 CDK6	4.88e-06	8	156	3	9716181
Pubmed	Cdc2-cyclin E complexes regulate the G1/S phase transition.	CCNA2 CDK1 CDK4	4.88e-06	8	156	3	16007079
Pubmed	APOLLON protein promotes early mitotic CYCLIN A degradation independent of the spindle assembly checkpoint.	CCNA2 CDK1 CDK4	4.88e-06	8	156	3	24302728
Pubmed	Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6.	CCNA2 CDK1 CDK6	4.88e-06	8	156	3	10339564
Pubmed	Association of cyclin-dependent kinase 5 and its activator p35 with apoptotic cell death.	CDK1 CDK4 CDK6	7.29e-06	9	156	3	9438340
Pubmed	PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2.	PKD1 CDK4 CDK6	7.29e-06	9	156	3	12007403
Pubmed	Cell cycle regulation in mouse heart during embryonic and postnatal stages.	CCNA2 CDK1 CDK4	7.29e-06	9	156	3	22957921
Pubmed	Cyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73.	CCNA2 CDK1 CDK4	7.29e-06	9	156	3	12676926
Pubmed	NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor.	CCNA2 CDK1 CDK4 CDK6	7.33e-06	28	156	4	21952639
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SMG1 RC3H2 CDK12 DHX57 TTLL12 CASKIN2 WDR6 SLC22A4 TUBGCP3 PRKAA1 OSBPL11 TMCO1 AP3D1	8.17e-06	650	156	13	38777146
Pubmed	Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons.	STAG1 CCNA2 CDK1 CDK4 CDK6	8.27e-06	61	156	5	34746147
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK4 SPTBN1 PAK5 TTLL12 FAM117A FAM171A2 MEGF8 PIK3C2B CASKIN2 NEURL1 MAP3K10 FAM83G KIF14 BAIAP2 ARAP2	8.44e-06	861	156	15	36931259
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FN1 NPEPPS SPTBN1 NUP88 DHX57 DDX10 TTLL12 URB1 WDR6 FANCI KIF14 UQCRC1 LAS1L	8.58e-06	653	156	13	22586326
Pubmed	BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases.	CCNA2 CDK1 CDK4	1.04e-05	10	156	3	9244350
Pubmed	PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis.	CCNA2 CDK1 CDK6	1.04e-05	10	156	3	9885575
Pubmed	Direct interaction of p21 cyclin-dependent kinase inhibitor with the retinoblastoma tumor suppressor protein.	CCNA2 CDK4 CDK6	1.04e-05	10	156	3	10486249
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	HDAC6 FN1 MARS1 NPEPPS SPTBN1 DHX57 LDHB PGD SLC2A1 DDX10 URB1 WDR6 FANCI TUBGCP3 ASPM CDK1 UQCRC1 LAS1L AP3D1	1.12e-05	1353	156	19	29467282
Pubmed	A p27Kip1 mutant that does not inhibit CDK activity promotes centrosome amplification and micronucleation.	CCNA2 CDK1 CDK4	1.42e-05	11	156	3	22158041
Pubmed	Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage.	CCNA2 CDK1 CDK4	1.42e-05	11	156	3	8662825
Pubmed	Proliferation inhibition of astrocytes, neurons, and non-glial cells by intracellularly expressed human immunodeficiency virus type 1 (HIV-1) Tat protein.	CCNA2 CDK1 CDK4	1.42e-05	11	156	3	15050687
Pubmed	Functional proteomics mapping of a human signaling pathway.	THAP5 SMG1 FN1 STAG1 DOCK8 CDK12 SPTBN1 TENM3 PPP1R15B PKD1 LRP1 GGA1	1.59e-05	591	156	12	15231748
Pubmed	Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth.	CCNA2 CDK1 CDK4 CDK6	1.63e-05	34	156	4	23342106
Pubmed	The protein interaction landscape of the human CMGC kinase group.	LPCAT1 CDK12 CDK10 CCNA2 FAM117A WDR6 PRKAA1 CDK1 BAIAP2 MED23 CDK4 DYRK3 CDK6	1.65e-05	695	156	13	23602568
Pubmed	CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome.	CDK10 CDK1 CDK4	1.89e-05	12	156	3	24218572
Pubmed	Ubiquitin C-terminal hydrolase L1 (UCH-L1) acts as a novel potentiator of cyclin-dependent kinases to enhance cell proliferation independently of its hydrolase activity.	CDK1 CDK4 CDK6	1.89e-05	12	156	3	23543736
Pubmed	Functional interaction of Puralpha with the Cdk2 moiety of cyclin A/Cdk2.	CCNA2 CDK1 CDK4	1.89e-05	12	156	3	15707957
Pubmed	Regulation of cyclin and cyclin-dependent kinase gene expression during lens differentiation requires the retinoblastoma protein.	CCNA2 CDK1 CDK4	1.89e-05	12	156	3	8552401
Pubmed	Cyclin-dependent kinase-mediated phosphorylation of RBP1 and pRb promotes their dissociation to mediate release of the SAP30·mSin3·HDAC transcriptional repressor complex.	CCNA2 CDK1 CDK4	1.89e-05	12	156	3	21148318
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	RC3H2 VPS11 NUP88 ELP6 CASKIN2 TUBGCP3 KIF14 CDK1	1.90e-05	251	156	8	29778605
Pubmed	Cyclin A-Cdk1 regulates the origin firing program in mammalian cells.	CCNA2 CDK1	2.00e-05	2	156	2	19221029
Pubmed	Novel mutations in human and mouse SCN4A implicate AMPK in myotonia and periodic paralysis.	SCN4A PRKAA1	2.00e-05	2	156	2	25348630
Pubmed	Defining the transcriptional and biological response to CDK4/6 inhibition in relation to ER+/HER2- breast cancer.	CDK4 CDK6	2.00e-05	2	156	2	27564114
Pubmed	AMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression.	CCNA2 PRKAA1	2.00e-05	2	156	2	24012615
Pubmed	A Phase I Study of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib (LEE011) in Patients with Advanced Solid Tumors and Lymphomas.	CDK4 CDK6	2.00e-05	2	156	2	27542767
Pubmed	To Cycle or Fight-CDK4/6 Inhibitors at the Crossroads of Anticancer Immunity.	CDK4 CDK6	2.00e-05	2	156	2	30224338
Pubmed	Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1.	CDK4 CDK6	2.00e-05	2	156	2	32294430
Pubmed	Induction of Therapeutic Senescence in Vemurafenib-Resistant Melanoma by Extended Inhibition of CDK4/6.	CDK4 CDK6	2.00e-05	2	156	2	26988987
Pubmed	Anatomy of CD1-lipid antigen complexes.	CD1A CD1B	2.00e-05	2	156	2	15864273
Pubmed	Small-molecule compounds boost genome-editing efficiency of cytosine base editor.	ABCA4 HDAC6	2.00e-05	2	156	2	34329468
Pubmed	RB expression confers sensitivity to CDK4/6 inhibitor-mediated radiosensitization across breast cancer subtypes.	CDK4 CDK6	2.00e-05	2	156	2	34932500
Pubmed	Beyond the Cell Cycle: Enhancing the Immune Surveillance of Tumors Via CDK4/6 Inhibition.	CDK4 CDK6	2.00e-05	2	156	2	29934327
Pubmed	Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease.	HDAC6 PKD1	2.00e-05	2	156	2	28887310
Pubmed	Negative regulation of AMPKα1 by PIM2 promotes aerobic glycolysis and tumorigenesis in endometrial cancer.	PIM2 PRKAA1	2.00e-05	2	156	2	31358902
Pubmed	CDK4/6 Inhibition Sensitizes Intracranial Tumors to PD-1 Blockade in Preclinical Models of Brain Metastasis.	CDK4 CDK6	2.00e-05	2	156	2	37611074
Pubmed	Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6-independent manner.	CDK4 CDK6	2.00e-05	2	156	2	28453226
Pubmed	Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma.	CDK4 CDK6	2.00e-05	2	156	2	30899002
Pubmed	CDK4/6 are necessary for UCP1-mediated thermogenesis of white adipose tissue.	CDK4 CDK6	2.00e-05	2	156	2	37011871
Pubmed	Deciphering the Immunomodulatory Role of Cyclin-Dependent Kinase 4/6 Inhibitors in the Tumor Microenvironment.	CDK4 CDK6	2.00e-05	2	156	2	36768557
Pubmed	Role of protein kinase A and class II phosphatidylinositol 3-kinase C2β in the downregulation of KCa3.1 channel synthesis and membrane surface expression by lyso-globotriaosylceramide.	PIK3C2B KCNN4	2.00e-05	2	156	2	26820527
Pubmed	Protein kinase D1 mediates synergistic MMP-3 expression induced by TNF-α and bradykinin in human colonic myofibroblasts.	PKD1 MMP3	2.00e-05	2	156	2	21867693
Pubmed	The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein.	PKD1 PKHD1	2.00e-05	2	156	2	11919560
Pubmed	The Immunological Role of CDK4/6 and Potential Mechanism Exploration in Ovarian Cancer.	CDK4 CDK6	2.00e-05	2	156	2	35095879
Pubmed	The class II phosphatidylinositol 3 kinase C2beta is required for the activation of the K+ channel KCa3.1 and CD4 T-cells.	PIK3C2B KCNN4	2.00e-05	2	156	2	19587117
Pubmed	Targeting the cyclin-dependent kinases (CDK) 4/6 in estrogen receptor-positive breast cancers.	CDK4 CDK6	2.00e-05	2	156	2	26857361
Pubmed	Expression of cyclin-dependent kinase 6, but not cyclin-dependent kinase 4, alters morphology of cultured mouse astrocytes.	CDK4 CDK6	2.00e-05	2	156	2	12861051
Pubmed	Upregulation of Cdc2 and cyclin A during apoptosis of endothelial cells induced by cleaved high-molecular-weight kininogen.	CCNA2 CDK1	2.00e-05	2	156	2	12742823
Pubmed	Inhibition of CDK4/6 kinases causes production of aneuploid oocytes by inactivating the spindle assembly checkpoint and accelerating first meiotic progression.	CDK4 CDK6	2.00e-05	2	156	2	33865884
Pubmed	Altered G1 signaling order and commitment point in cells proliferating without CDK4/6 activity.	CDK4 CDK6	2.00e-05	2	156	2	33082317
Pubmed	Physiologically Based Pharmacokinetic Modeling of Central Nervous System Pharmacokinetics of CDK4/6 Inhibitors to Guide Selection of Drug and Dosing Regimen for Brain Cancer Treatment.	CDK4 CDK6	2.00e-05	2	156	2	32799335
Pubmed	Inhibition of CDK4/6 regulates AD pathology, neuroinflammation and cognitive function through DYRK1A/STAT3 signaling.	CDK4 CDK6	2.00e-05	2	156	2	36907286
Pubmed	Modification of the DNA damage response by therapeutic CDK4/6 inhibition.	CDK4 CDK6	2.00e-05	2	156	2	22733811
Pubmed	A CDK4/6-Dependent Epigenetic Mechanism Protects Cancer Cells from PML-induced Senescence.	CDK4 CDK6	2.00e-05	2	156	2	27206849
Pubmed	Sequences within the conserved cyclin box of human cyclin A are sufficient for binding to and activation of cdc2 kinase.	CCNA2 CDK1	2.00e-05	2	156	2	8423786
Pubmed	Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy.	ABCA4 NRL	2.00e-05	2	156	2	22033104
Pubmed	Pathogenicity analysis of novel variations in Chinese Han patients with polycystic kidney disease.	PKD1 PKHD1	2.00e-05	2	156	2	28578020
Pubmed	Inducible deletion of CDK4 and CDK6 - deciphering CDK4/6 inhibitor effects in the hematopoietic system.	CDK4 CDK6	2.00e-05	2	156	2	32855282
Pubmed	Ovarian cancer cell heparan sulfate 6-O-sulfotransferases regulate an angiogenic program induced by heparin-binding epidermal growth factor (EGF)-like growth factor/EGF receptor signaling.	HS6ST2 HS6ST1	2.00e-05	2	156	2	24563483
Pubmed	Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties.	HS6ST2 HS6ST1	2.00e-05	2	156	2	12492399
Pubmed	Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability.	CACNA1C PKD1	2.00e-05	2	156	2	25888683
Pubmed	Differential Regulation of Cancer Progression by CDK4/6 Plays a Central Role in DNA Replication and Repair Pathways.	CDK4 CDK6	2.00e-05	2	156	2	33372040
Pubmed	Mechanisms of resistance to cyclin-dependent kinase 4/6 inhibitors.	CDK4 CDK6	2.00e-05	2	156	2	33409716
Pubmed	The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.	FN1 LRP1	2.00e-05	2	156	2	11867643
Pubmed	Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation.	CDK4 CDK6	2.00e-05	2	156	2	32255427
Pubmed	CDK4/6 Inhibitor PD 0332991 Sensitizes Acute Myeloid Leukemia to Cytarabine-Mediated Cytotoxicity.	CDK4 CDK6	2.00e-05	2	156	2	25744718
Pubmed	Expression patterns and prognostic values of the cyclin-dependent kinase 1 and cyclin A2 gene cluster in pancreatic adenocarcinoma.	CCNA2 CDK1	2.00e-05	2	156	2	33290118
Pubmed	Understanding divergent trial results of adjuvant CDK4/6 inhibitors for early stage breast cancer.	CDK4 CDK6	2.00e-05	2	156	2	33689702
Pubmed	MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase.	MAP2K4 MAP3K10	2.00e-05	2	156	2	9182538
Pubmed	SMG1 and CDK12 Link ΔNp63α Phosphorylation to RNA Surveillance in Keratinocytes.	SMG1 CDK12	2.00e-05	2	156	2	34761935
Pubmed	Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts.	CDK4 CDK6	2.00e-05	2	156	2	20354191
Pubmed	7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4.	MAP2K4 MAP3K8	2.00e-05	2	156	2	21378167
Pubmed	LRP1 is required for novobiocin-mediated fibronectin turnover.	FN1 LRP1	2.00e-05	2	156	2	30061663
Pubmed	Palbociclib and cetuximab in platinum-resistant and in cetuximab-resistant human papillomavirus-unrelated head and neck cancer: a multicentre, multigroup, phase 2 trial.	CDK4 CDK6	2.00e-05	2	156	2	31351869
Pubmed	Alteration in the expression of cdk4 and cdk6 proteins in oral cancer and premalignant lesions.	CDK4 CDK6	2.00e-05	2	156	2	20618617
Pubmed	Enhancement of metastatic activity of colon cancer as influenced by expression of cell surface antigens.	FN1 ITGA3	2.00e-05	2	156	2	9733622
GeneFamily	Cyclin dependent kinases	CDK12 CDK10 CDK1 CDK4 CDK6	4.52e-07	26	110	5	496
Coexpression	FERRANDO_HOX11_NEIGHBORS	ERCC1 CCNA2 CD1A CD1B	9.79e-06	23	156	4	M2059
Coexpression	WINTER_HYPOXIA_METAGENE	VPS11 FN1 PIM2 GBE1 LDHB SLC2A1 BTG1 LRP1 CDK1	1.59e-05	243	156	9	M14072
Coexpression	PRC2_SUZ12_UP.V1_DN	MAP2K4 CRYBG2 LPCAT1 MARK1 ELP6 SLITRK3 ATG2A CD1B	2.06e-05	192	156	8	M2740
Coexpression	GSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_DN	CHRNA9 MARK1 BCORL1 ITGA2B PGD NPHP3 FAM171A2 TPRG1	2.76e-05	200	156	8	M6798
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARSJ DOCK8 MAP3K8 SH3TC1 PTPRZ1 KCNJ6 NEURL1 TPRG1 SLC4A9	7.66e-09	165	157	9	dc570154baed59ed109e5369589448e075ba66a9
ToppCell	COVID-19-lung-Proliferative_fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	CACNA1C FN1 CCNA2 TENM3 CCBE1 FANCI ASPM KIF14 CDK1	3.41e-08	196	157	9	2ce8a787f2731faa913d20342d73041d59468f27
ToppCell	356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|356C / Donor, Lineage, Cell class and subclass (all cells)	PNMT ITGA2B CCNA2 FAM117A ASPM KIF14 CDK1 CDK6	2.69e-07	181	157	8	be4f35c9eb5b3083acb2264128f095fac1f3da45
ToppCell	wk_20-22-Hematologic-Myeloid-MEP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MPL PNMT ITGA2B CCNA2 ASPM KCNN4 KIF14 CDK1	3.31e-07	186	157	8	e6e9135a65da568b3a7d0e378f8ce9ae34483968
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LDHB CCNA2 PTPRZ1 FANCI ASPM CDK1 CDK4 CDK6	5.33e-07	198	157	8	06888fe2d42ac66ac12157608becd42764e0d034
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ZMYND15 BCORL1 CCNA2 FANCI VSIG10L ASPM CDK1 ZNF324B	5.53e-07	199	157	8	c6d59ed26eadd3c41acfe1b4d929270e00ea3e95
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	CRYBG2 PTPRZ1 CCBE1 HS6ST1 KCNN4 TPRG1 MMP3	1.86e-06	163	157	7	f21951e63188eb0c04675a8f81a0da495c26c007
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCA4 LDHB CCNA2 FAM187B ASPM KIF14 CDK1	2.18e-06	167	157	7	a90f905ef38437752e2b0b71bd0322a184de1861
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_1\|390C / Donor, Lineage, Cell class and subclass (all cells)	WDFY4 CCNA2 FANCI ASPM KCNN4 KIF14 CDK1	2.27e-06	168	157	7	2082b15fc7935a211f1c61506b305af5501a21ad
ToppCell	Int-URO-Lymphocyte-T_NK-CD4_TEM\|Int-URO / Disease, Lineage and Cell Type	CACNA1C CRYBG2 PIM2 ACTRT3 LDHB BTG1 TPRG1	2.36e-06	169	157	7	5b2fb89cbc9b92d609994d6e5aa35a67c3cc8f22
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZMYND15 FN1 DOCK8 LRP1 GM2A ZFYVE26 GAA	2.87e-06	174	157	7	d5c22b43531414951666ee7542a66ed9380e2d14
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PNMT MTFP1 CCNA2 CASKIN2 FANCI ASPM CDK1	2.98e-06	175	157	7	86dfce849b2ec023a72f7e887fa681b117155e51
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LPCAT1 TEX15 LDHB CCNA2 FANCI ASPM CDK1	3.21e-06	177	157	7	a68c3688f12aee22f3cb4049c4bccacbacb0fae6
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MARK1 RET NSMCE3 FAM171A2 PTPRZ1 SLC22A4 DYRK3	3.59e-06	180	157	7	c72f15763ba707189e29c85db533557f01c7fdb1
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|bone_marrow / Manually curated celltypes from each tissue	P4HA3 PGD CCNA2 FANCI ASPM KIF14 CDK1	3.72e-06	181	157	7	ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LPCAT1 PIM2 SSUH2 DPEP2 BTG1 PKHD1 SERINC3	4.30e-06	185	157	7	42690b95e2e7d56c822211bb1150acb787cfe2e8
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	SMG1 STAG1 CDK12 GNPTAB PRKAA1 OSBPL11 TET3	4.45e-06	186	157	7	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 CCNA2 FANCI ASPM KIF14 CDK1 AMIGO2	5.68e-06	193	157	7	444de545117dae8ab24a22880583ac2f0b2d6eac
ToppCell	RA-08._Macrophage\|World / Chamber and Cluster_Paper	DOCK4 DOCK8 MAP3K8 WDFY4 SH3TC1 TET3 MUC6	5.68e-06	193	157	7	5fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCell	RA-08._Macrophage\|RA / Chamber and Cluster_Paper	DOCK4 DOCK8 MAP3K8 WDFY4 SH3TC1 TET3 MUC6	5.87e-06	194	157	7	ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PNMT NRL HEATR4 TMEM114 CCBE1 AMIGO2	5.99e-06	127	157	6	9bc55cb9f4bddb274930784d12a83b9dceb35cb7
ToppCell	Immune-alveolar_macrophage_(MARCO_positive)\|World / Lineage, Cell type, age group and donor	DOCK8 WDFY4 PGD LRP1 OSBPL11 TPRG1 AMIGO2	6.07e-06	195	157	7	f92114ef995e690a3bedc62c89c5fd6773d0d9f7
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	DOCK8 MAP3K8 WDFY4 SH3TC1 LRP1 TPRG1 TET3	6.07e-06	195	157	7	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_1\|343B / Donor, Lineage, Cell class and subclass (all cells)	CCNA2 CD1A CD1B FANCI ASPM KCNN4 CDK1	6.07e-06	195	157	7	47a01b8a92eebeb34ac7f70bf1ab4613a326e24f
ToppCell	COVID-19-lung-Proliferative_fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FN1 CCNA2 CCBE1 FANCI ASPM KIF14 CDK1	6.28e-06	196	157	7	ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CCNA2 NOD1 FANCI ASPM KIF14 CDK1 EPHA1	6.28e-06	196	157	7	36ed1918f70b6f5760bb088b15ce422998055cc7
ToppCell	myeloid-CD34+_Monoblast\|myeloid / Lineage and Cell class	LDHB CCNA2 FANCI ASPM CDK1 CDK4 CDK6	6.71e-06	198	157	7	e26b98a8380e693110a97d8e5a353998f8d67c6d
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 WDFY4 DPEP2 LRP1 OSBPL11 TPRG1 AMIGO2	6.71e-06	198	157	7	e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 WDFY4 DPEP2 LRP1 OSBPL11 TPRG1 AMIGO2	6.71e-06	198	157	7	0baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DOCK4 ERCC1 DOCK8 WDFY4 SH3TC1 ARHGAP27 GAA	6.93e-06	199	157	7	b0a906586e58009f5ed9272fc29ba28e49c85ee6
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LPCAT1 CCNA2 FANCI SUSD2 ASPM KIF14 CDK1	6.93e-06	199	157	7	6a89c3a65fa50af92585c52bec203bcff6f94efc
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2_proliferating-AT2_proliferating_L.0.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LPCAT1 CCNA2 FANCI SUSD2 ASPM KIF14 CDK1	6.93e-06	199	157	7	d7dbc551c05da32c698908348572fb0ce1166e10
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	THAP5 PANX2 WDFY4 SSUH2 FAM117A DPEP2 MAP3K10	6.93e-06	199	157	7	7271dbeca9aa838b88ad44d00059263a29c0316b
ToppCell	BAL-Severe-cDC_0\|Severe / Compartment, Disease Groups and Clusters	FN1 PGD DPEP2 LRP1 UQCRC1 LILRB5 GAA	6.93e-06	199	157	7	d39be8b173156bf87baddd3caed4b35597c53ea1
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SSUH2 FAM187B ASPM KCNN4 CDK1	1.97e-05	93	157	5	b3e057132633b25bd4f8ff2c0aa203ade0f3ba4c
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)--\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SSUH2 FAM187B ASPM KCNN4 CDK1	1.97e-05	93	157	5	38a075f06001a2fd1ec77fc301a08a87618a2440
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SSUH2 FAM187B ASPM KCNN4 CDK1	1.97e-05	93	157	5	a0117b12889d9c48294a7ccea4284d00c087889f
ToppCell	facs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIM2 TMEM151B CCNA2 SCN4A ASPM KIF14	2.01e-05	157	157	6	0fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCell	facs-Marrow-B-cells-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZMYND15 FN1 TENM3 DPEP2 LRP1 GM2A	2.01e-05	157	157	6	0966e347f8d32b13f8a3b3afba3f64637c69cdf9
ToppCell	facs-Marrow-B-cells-24m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZMYND15 FN1 TENM3 DPEP2 LRP1 GM2A	2.01e-05	157	157	6	6ebfedd91d62c6d4aa8f046657a899a279f82ba2
ToppCell	390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	ITGA2B CCNA2 FANCI ASPM KIF14 CDK1	2.16e-05	159	157	6	0fbfdb18b7ed4bde077add13f2b3636e144b254f
ToppCell	droplet-Heart-nan-18m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS11 WDFY4 CCNA2 FAM187B FANCI DYRK3	2.40e-05	162	157	6	7f425a3983325a5a3ea33f812b15aa010cc55de0
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LCT CD1A CD1B ASPM KIF14 ARAP2	2.40e-05	162	157	6	a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCell	390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ITGA2B CCNA2 FANCI ASPM KIF14 CDK1	2.48e-05	163	157	6	aa5ea367f787c1543afb7eb80a801432e1c44011
ToppCell	wk_20-22-Hematologic-Myeloid-HSC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MPL LDHB FAM117A DPEP3 KCNN4 CDK6	2.57e-05	164	157	6	a35a0725b8bfe3cad5b85484217fd8a02bdee827
ToppCell	normal_Pleural_Fluid-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	ITGA3 SLC2A1 CCNA2 ASPM KIF14 CDK1	2.75e-05	166	157	6	d16af6570806ed2880bd0efb5298932fd2a89cf5
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNA2 SCN4A PKHD1 OSBPL11 SERINC3 CDK1	2.75e-05	166	157	6	bb8135119dc37fdbba476599a56d368f422688dc
ToppCell	Dividing_Macrophages-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	CCNA2 ZP1 FANCI ASPM KIF14 CDK1	2.75e-05	166	157	6	ea95b94ccc2ac67df741b30c27f4ae698925875f
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	ITGA2B CCNA2 ASPM KIF14 CDK1 CDK6	2.84e-05	167	157	6	315cde87eed2b42a1b9b068fae94caa10ec64c70
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WDFY4 CCNA2 DPEP2 ASPM ZFYVE26 CDK1	2.94e-05	168	157	6	9b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic-cDC1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WDFY4 CCNA2 DPEP2 ASPM ZFYVE26 CDK1	2.94e-05	168	157	6	4b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WDFY4 CCNA2 DPEP2 ASPM ZFYVE26 CDK1	2.94e-05	168	157	6	c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTRT3 CCNA2 FANCI ASPM KIF14 CDK1	3.04e-05	169	157	6	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FAM187B ASPM FAM83G KCNN4 C16orf54	3.08e-05	102	157	5	2c3622fc3cd62d9b7e185d0204cf7f03e7dde73c
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO10 RET CCNA2 FANCI TUBGCP3 KIF14	3.24e-05	171	157	6	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO10 RET CCNA2 FANCI TUBGCP3 KIF14	3.24e-05	171	157	6	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPL DOCK8 WDFY4 FAM117A KCNN4 CDK1	3.24e-05	171	157	6	c60313b045cb77c0923ddb81bbd1a654aa1087c5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 CCNA2 FANCI ASPM KIF14 CDK1	3.58e-05	174	157	6	c26eac176e9b0cba385630fdc60e0314a4e4caac
ToppCell	18-Distal-RBC\|Distal / Age, Tissue, Lineage and Cell class	PIM2 PNMT WDFY4 SLC2A1 KCNN4 TET3	3.69e-05	175	157	6	cc476b4244442418b8f21721a82a36209b556b36
ToppCell	18-Distal-RBC-RBC\|Distal / Age, Tissue, Lineage and Cell class	PIM2 PNMT WDFY4 SLC2A1 KCNN4 TET3	3.69e-05	175	157	6	7130b816e0c02309c161d8e9ad7cb4bc2469e251
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZMYND15 DOCK8 PIK3C2B DPEP2 PPP1R15B LRP1	3.69e-05	175	157	6	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ARSJ SH3TC1 CCBE1 KCNJ6 NEURL1 SLC4A9	3.81e-05	176	157	6	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	SMG1 ACTRT3 GNPTAB URB1 PPP1R15B CDK6	3.81e-05	176	157	6	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_2\|356C / Donor, Lineage, Cell class and subclass (all cells)	CCNA2 CD1A ASPM KCNN4 CDK1 LILRB5	3.81e-05	176	157	6	4bba41ebf9dd187c8705a6997ed039878de62b4e
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	SMG1 ACTRT3 GNPTAB URB1 PPP1R15B CDK6	3.93e-05	177	157	6	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	P4HA3 CCNA2 TENM3 ASPM CDK1 MMP3	3.93e-05	177	157	6	4197cf2b1e743230c821f422836fa5991b155a52
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_1\|367C / Donor, Lineage, Cell class and subclass (all cells)	CCNA2 CD1A FANCI ASPM KIF14 CDK1	3.93e-05	177	157	6	ba701d3c90722d8bff70d0fa651899305cdad257
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELP6 TEX15 CCNA2 ASPM CDK1 TARBP1	4.19e-05	179	157	6	54621d2b3a66e62aa76b7e444118878ed97c1e02
ToppCell	367C-Lymphocytic-ILC-ILC-2\|ILC / Donor, Lineage, Cell class and subclass (all cells)	ANO10 ATG2A UQCRC1 ARAP2	4.24e-05	55	157	4	7916216b3a24f9c6b966aa5392fc2bc43b3d2c4c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARSJ DOCK8 CCBE1 KCNJ6 NEURL1 SLC4A9	4.32e-05	180	157	6	cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell	Control-Myeloid-Alveolar_macrophages\|Control / group, cell type (main and fine annotations)	FN1 WDFY4 LRP1 OSBPL11 TPRG1 GAA	4.46e-05	181	157	6	8d2102c8c86c59a82610f26f90946b290552e666
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCNA2 DPEP2 FANCI ASPM KIF14 CDK1	4.46e-05	181	157	6	73b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCell	Healthy_Control-Lymphoid-T-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	SPTBN1 CCNA2 FANCI ASPM KIF14 CDK1	4.46e-05	181	157	6	ac1ee313910c05b1b3cb497bae14565464919c21
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	RC3H2 VPS11 PIM2 SH3TC1 MED23 CDK6	4.46e-05	181	157	6	b193f3606554adc55c5906219d114288bb1f978a
ToppCell	mild_COVID-19_(asymptomatic)-T/NK_proliferative\|World / disease group, cell group and cell class (v2)	LCT CCNA2 FANCI ASPM KIF14 CDK1	4.60e-05	182	157	6	9adf90bb2808f234d53b89ca0ae07380478204ad
ToppCell	severe-multiplets\|World / disease stage, cell group and cell class	ITGA2B CCNA2 ZP1 DPEP3 KIF14 CDK1	4.60e-05	182	157	6	5e30ec7120a988d9ee3000513e1209618f28f5f9
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPL CCNA2 FANCI ASPM KIF14 CDK1	4.60e-05	182	157	6	0fc45214f0b0766f69be6eff69cc4bec574023aa
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPL CCNA2 FANCI ASPM KIF14 CDK1	4.60e-05	182	157	6	bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCell	COVID-19-Epithelial_cells-ECM-high_epithelial\|COVID-19 / group, cell type (main and fine annotations)	CACNA1C LPCAT1 FN1 HS6ST2 SPTBN1 ITGA3	4.74e-05	183	157	6	dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCell	severe-multiplets\|severe / disease stage, cell group and cell class	ITGA2B CCNA2 ZP1 DPEP3 KIF14 CDK1	4.74e-05	183	157	6	78af8df48f0fe49ac37ccec0ad7b2993883b1148
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ITGA2B CCNA2 MEGF8 ASPM KIF14 CDK1	4.74e-05	183	157	6	f03d87b556a3d50360d4eb6126b3466fe7266677
ToppCell	mild_COVID-19_(asymptomatic)-T/NK_proliferative\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	LCT CCNA2 FANCI ASPM KIF14 CDK1	4.74e-05	183	157	6	df8568751205313d149939ea2683097e3652a60b
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMK+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	MAP3K8 MTFP1 ATG2A BTG1 TPRG1 ARAP2	4.74e-05	183	157	6	79defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCell	wk_15-18-Hematologic-Meg-ery-Cycling_definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SLC2A1 CCNA2 FANCI SLC22A4 ASPM KCNN4	4.88e-05	184	157	6	238eba615b4e04967d44ac7858a6673bdd7f67e9
ToppCell	wk_08-11-Epithelial-PNS-COL20A1+_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	DOCK8 HS6ST2 TENM3 IL1RAPL2 PTPRZ1 KCNN4	5.03e-05	185	157	6	abec2a49fe0f0fa4cba49347207a1ee317333657
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	HS6ST2 RET IL1RAPL2 PTPRZ1 ARAP2 AMIGO2	5.03e-05	185	157	6	a8946379fc066903fe8f4bc9cbf693b7b424a0cd
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HS6ST2 RET GRM3 IL1RAPL2 PTPRZ1 MMP3	5.03e-05	185	157	6	5a0340c25196453f19e424d346efbf66d2c53ac3
ToppCell	Control-Myeloid-MoAM5\|Control / Disease group,lineage and cell class （2021.01.30）	MTFP1 SLC2A1 AARS2 FAM83G KCNN4 FCRL4	5.34e-05	187	157	6	8769341be67382cea2a590d962f4def7c39de883
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 TENM3 FANCI ASPM KIF14 CDK1	5.34e-05	187	157	6	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	BAL-Control-Myeloid-MoAM-MoAM5-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MTFP1 SLC2A1 AARS2 FAM83G KCNN4 FCRL4	5.34e-05	187	157	6	0d589de12108230ced5b60229564f4a181e2f172
ToppCell	BAL-Control-Myeloid-MoAM-MoAM5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MTFP1 SLC2A1 AARS2 FAM83G KCNN4 FCRL4	5.34e-05	187	157	6	59d28f4ee1d463ae20abb8d7e7399b504d80698a
ToppCell	BAL-Control-Myeloid-MoAM-MoAM5-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MTFP1 SLC2A1 AARS2 FAM83G KCNN4 FCRL4	5.34e-05	187	157	6	25adf648c05c21534b4913254e73d43fc5f64e06
ToppCell	BAL-Control-Myeloid-MoAM-MoAM5\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	MTFP1 SLC2A1 AARS2 FAM83G KCNN4 FCRL4	5.34e-05	187	157	6	3b0cfa9e5ea5e7d6dda689c328b9b5110b43ee1d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 TENM3 FANCI ASPM KIF14 CDK1	5.34e-05	187	157	6	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	3'_v3-Lung-Myeloid_Dendritic-Cycling_Dendritic\|Lung / Manually curated celltypes from each tissue	CCNA2 CD1A CD1B FANCI ASPM CDK1	5.50e-05	188	157	6	0e8ac42c439f30a05e015210e1d5c2dcb9d9d471
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	TEX15 WDFY4 CCNA2 PLEKHH1 KIF14 CDK1	5.50e-05	188	157	6	723348a1836a074e068320cb736ce6a953e0038f
ToppCell	normal-na-Lymphocytic\|normal / PBMC cell types (v2) per disease, treatment status, and sex	LCT CCNA2 FANCI ASPM KIF14 CDK1	5.67e-05	189	157	6	1d382f8eb998c6a30e09fddc9a427afc8f5f7323
ToppCell	Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	FN1 DOCK8 LRP1 OSBPL11 GAA AMIGO2	5.67e-05	189	157	6	c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell	normal-na-Lymphocytic-lymphocyte\|normal / PBMC cell types (v2) per disease, treatment status, and sex	LCT CCNA2 FANCI ASPM KIF14 CDK1	5.67e-05	189	157	6	b83fd81ecc5ef363be7435ee12cb7079e2434af7
ToppCell	normal-na-Lymphocytic-lymphocyte-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	LCT CCNA2 FANCI ASPM KIF14 CDK1	5.67e-05	189	157	6	3db4177d68cab4cd16842d2ebcaca28f69300e44
Computational	Neighborhood of CCNA2	CCNA2 FANCI ASPM KIF14 CDK1	2.53e-04	68	90	5	GNF2_CCNA2
Computational	Neighborhood of TTK	CCNA2 FANCI ASPM CDK1	3.02e-04	39	90	4	GNF2_TTK
Computational	Neighborhood of RFC3	CCNA2 FANCI ASPM CDK1	3.67e-04	41	90	4	GNF2_RFC3
Computational	Neighborhood of BUB1B	CCNA2 FANCI ASPM KIF14	7.30e-04	49	90	4	GNF2_BUB1B
Computational	Neighborhood of CKS2	CCNA2 FANCI ASPM CDK1	7.89e-04	50	90	4	GNF2_CKS2
Computational	Neighborhood of RRM1	CCNA2 FANCI ASPM KIF14 CDK1	8.35e-04	88	90	5	GNF2_RRM1
Computational	Lymphoma and immune response expression clusters.	PANX2 ITGA3 CCNA2 ASPM CDK1 CDK4 DYRK3	8.40e-04	183	90	7	MODULE_126
Computational	Response to DNA damage.	MAP3K8 DDX10 KIF14 CDK1 CDK4 DYRK3 CDK6	9.54e-04	187	90	7	MODULE_244
Computational	Neighborhood of MCM4	CCNA2 FANCI ASPM KIF14	9.84e-04	53	90	4	GNF2_MCM4
Drug	Methionylmethionine	LCT DPEP2 DPEP3 GAA	2.60e-07	9	156	4	CID000104294
Drug	glycyl-L-leucine	LCT DPEP2 DPEP3 LRP1 MMP3 GAA	1.85e-06	54	156	6	CID000092843
Drug	NSC683246	CACNA1C CDK12 CDK10 CCNA2 NPHP3 PKD1 PKHD1 CDK1 CDK4 CDK6	5.13e-06	234	156	10	CID000005097
Drug	Deferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A	MPL FN1 NRL TEX15 GRM3 SLC2A1 EFNB3 SCN4A ZNF324	9.41e-06	198	156	9	3842_UP
Drug	(R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; MCF7; HT_HG-U133A	DEAF1 PIM2 MARS1 BCORL1 DHX57 CDK10 KCNN4 ZNF324 EPHA1	1.02e-05	200	156	9	4841_DN
Drug	linarin	CDK1 CDK4 CDK6	1.08e-05	7	156	3	CID005317025
Drug	4 SP	CCNA2 CDK1 CDK4	1.08e-05	7	156	3	CID000004566
Drug	methyl ethyl ketone	MAP2K4 FN1 ACTRT3 MARK1 CDK12 MAP3K8 ITGA2B RET LDHB CDK10 CCNA2 MAP3K10 CDK1 CDK4 CDK6	1.31e-05	587	156	15	CID000006569
Drug	diallyl	MAP2K4 FN1 SPTBN1 CDK1	2.40e-05	25	156	4	CID000011598
Drug	HS 1030	CCNA2 CDK4 CDK6	2.57e-05	9	156	3	ctd:C403899
Drug	afimoxifene	MAP2K4 FN1 MAP3K8 NPEPPS SPTBN1 RET DDX10 PIK3C2B BTG1 PRKAA1 KCNN4 CDK1 EPHA1	2.73e-05	479	156	13	ctd:C016601
Drug	butyrolactone I	MAP2K4 CDK12 CDK10 CCNA2 CDK1 CDK4 CDK6	2.93e-05	128	156	7	CID000123740
Drug	SAHA; Up 200; 10uM; MCF7; HT_HG-U133A	DOCK4 FN1 BCORL1 ATG2A FAM117A EFNB3 BAIAP2 DYRK3	3.50e-05	180	156	8	6939_UP
Drug	olomoucine	CDK12 CDK10 CCNA2 CDK1 EPHA1 CDK4 CDK6	3.57e-05	132	156	7	CID000004592
Drug	HS 1183	CCNA2 CDK4 CDK6	3.66e-05	10	156	3	ctd:C403900
Drug	Flavopiridol	CDK1 CDK4 CDK6	3.66e-05	10	156	3	DB03496
Drug	silydianin	CCNA2 CDK1 CDK4 CDK6	3.82e-05	28	156	4	CID003033957
Drug	silychristin	CCNA2 CDK1 CDK4 CDK6	4.41e-05	29	156	4	CID000441764
Drug	Destruxin E	CCNA2 CDK4 CDK6	5.00e-05	11	156	3	CID000107863
Drug	Epitiostanol [2363-58-8]; Up 200; 13uM; MCF7; HT_HG-U133A	POMT2 MARS1 MAP3K8 SPTBN1 ATG2A RET NEURL1 EPHA1	5.33e-05	191	156	8	7342_UP
Drug	ST021200; Up 200; 10uM; PC3; HT_HG-U133A	RC3H2 TEX15 ITGA2B CDK10 TENM3 HEMK1 BAIAP2 ZNF324B	5.95e-05	194	156	8	7493_UP
Drug	Etomidate [33125-97-2]; Down 200; 16.4uM; MCF7; HT_HG-U133A	PIM2 NUP88 CDK10 CASKIN2 SLC22A4 PRKAA1 BAIAP2 ZNF324B	6.17e-05	195	156	8	3519_DN
Drug	Bufexamac [2438-72-4]; Down 200; 18uM; HL60; HT_HG-U133A	BCORL1 RET CDK10 URB1 IL1RAPL2 ARAP2 DYRK3 CDK6	6.39e-05	196	156	8	2382_DN
Drug	isosilybin B	CCNA2 CDK1 CDK4 CDK6	6.57e-05	32	156	4	CID003085830
Drug	Naloxone hydrochloride [357-08-4]; Up 200; 11uM; MCF7; HT_HG-U133A	POMT2 SPTBN1 TEX15 ITGA2B NOD1 EFNB3 GM2A DYRK3	6.63e-05	197	156	8	1506_UP
Drug	Acyclovir [59277-89-3]; Up 200; 17.8uM; MCF7; HT_HG-U133A	FN1 SPTBN1 EFNB3 TENM3 ZNF324 GM2A BAIAP2 CDK6	6.63e-05	197	156	8	1543_UP
Drug	Minoxidil [38304-91-5]; Up 200; 19.2uM; MCF7; HT_HG-U133A	PIM2 CHRNA9 SPTBN1 TEX15 ZNF324 GM2A BAIAP2 GGA1	6.63e-05	197	156	8	1496_UP
Drug	Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A	CRYBG2 GNPTAB SPTBN1 TEX15 GRM3 IL1RAPL2 NEURL1 GM2A	6.63e-05	197	156	8	3525_UP
Drug	Orphenadrine hydrochloride [341-69-5]; Up 200; 13uM; MCF7; HT_HG-U133A	POMT2 DEAF1 HDAC6 TEX15 CD1A EFNB3 SH3TC1 CPLANE1	6.63e-05	197	156	8	2318_UP
Drug	Tiletamine hydrochloride; Up 200; 15.4uM; HL60; HT_HG-U133A	CHRNA9 PAK5 CDK10 URB1 LRP1 ZNF324 HEMK1 MUC6	7.11e-05	199	156	8	3137_UP
Drug	Artemisinin [63968-64-9]; Up 200; 14.2uM; HL60; HG-U133A	RC3H2 DEAF1 FN1 NPEPPS CDK10 IL1RAPL2 NEURL1 GGA1	7.37e-05	200	156	8	1714_UP
Drug	Monocrotaline [315-22-0]; Up 200; 12.2uM; HL60; HG-U133A	DOCK4 DEAF1 TMEM151B CDK10 URB1 EFNB3 PIK3C2B NEURL1	7.37e-05	200	156	8	1757_UP
Drug	sorafenib	HDAC6 FN1 RET CCNA2 CDK1 CDK4 CDK6	7.70e-05	149	156	7	ctd:C471405
Drug	N6-9	CCNA2 CDK1 CDK4 CDK6	8.38e-05	34	156	4	CID009547890
Drug	UCN-01	MAP2K4 CDK12 CDK10 CCNA2 CDK1 CDK4 CDK6	9.48e-05	154	156	7	CID000072271
Disease	Profound Mental Retardation	DEAF1 STAG1 DOCK8 SLC2A1 CCNA2 CCBE1 TMCO1	9.20e-06	139	155	7	C0020796
Disease	Mental Retardation, Psychosocial	DEAF1 STAG1 DOCK8 SLC2A1 CCNA2 CCBE1 TMCO1	9.20e-06	139	155	7	C0025363
Disease	Mental deficiency	DEAF1 STAG1 DOCK8 SLC2A1 CCNA2 CCBE1 TMCO1	9.20e-06	139	155	7	C0917816
Disease	gastric adenocarcinoma (is_marker_for)	MAP2K4 CDK12 PTPRZ1 AMIGO2	1.36e-05	28	155	4	DOID:3717 (is_marker_for)
Disease	Intellectual Disability	DEAF1 STAG1 DOCK8 CDK10 SLC2A1 CCNA2 CCBE1 LAS1L MED23 TMCO1 TET3	2.61e-05	447	155	11	C3714756
Disease	level of dipeptidase 2 in blood serum	DPEP2 DPEP3	2.74e-05	2	155	2	OBA_2041349
Disease	non-functioning pancreatic endocrine tumor (is_marker_for)	CDK4 CDK6	2.74e-05	2	155	2	DOID:7698 (is_marker_for)
Disease	platelet crit	MPL CACNA1C VPS11 DEAF1 STAG1 NPEPPS HEATR4 ITGA2B TTLL12 CCBE1 KCNN4 UQCRC1 SLC41A1 EPHX3 GAA CDK6	4.41e-05	952	155	16	EFO_0007985
Disease	Medullary Neoplasms	CDK4 CDK6	1.63e-04	4	155	2	C0751887
Disease	Brain Stem Neoplasms, Primary	CDK4 CDK6	1.63e-04	4	155	2	C0751886
Disease	Pontine Tumors	CDK4 CDK6	1.63e-04	4	155	2	C0751889
Disease	Mesencephalic Neoplasms	CDK4 CDK6	1.63e-04	4	155	2	C0751888
Disease	Brain Stem Neoplasms	CDK4 CDK6	1.63e-04	4	155	2	C0677866
Disease	Malignant neoplasm of breast	MAP2K4 ABCA4 FN1 PCDHB15 BCORL1 PANX2 LDHB SLC2A1 DDX10 SLC2A10 IL1RAPL2 PRKAA1 OSBPL11 ZFYVE26 MMP3 GGA1	1.78e-04	1074	155	16	C0006142
Disease	Metastatic melanoma	MAP2K4 PAK5 MAP3K10 CDK6	1.89e-04	54	155	4	C0278883
Disease	Autosomal Recessive Primary Microcephaly	ASPM KIF14 CDK6	2.03e-04	22	155	3	C3711387
Disease	progranulin measurement	MAP2K4 ITGA2B FAM171A2	2.03e-04	22	155	3	EFO_0004625
Disease	Noninfiltrating Intraductal Carcinoma	LDHB SLC2A1	2.71e-04	5	155	2	C0007124
Disease	Atypical Ductal Breast Hyperplasia	LDHB SLC2A1	2.71e-04	5	155	2	C1332347
Disease	lung non-small cell carcinoma (is_marker_for)	ERCC1 MAP3K8 BCORL1 PRKAA1 CDK4 CDK6	2.79e-04	169	155	6	DOID:3908 (is_marker_for)
Disease	rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement	STAG1 TMEM151B WDFY4 TPRG1 TET3 CDK6	2.88e-04	170	155	6	EFO_0000685, EFO_0007791, EFO_0007837
Disease	liposarcoma	CDK4 CDK6	4.06e-04	6	155	2	C0023827
Disease	Myotonia	SLC2A1 SCN4A	4.06e-04	6	155	2	C0027125
Disease	Child Development Disorders, Specific	DOCK8 WDFY4 SLC2A1	4.70e-04	29	155	3	C0085997
Disease	Child Development Deviations	DOCK8 WDFY4 SLC2A1	4.70e-04	29	155	3	C0085996
Disease	Developmental Disabilities	DOCK8 WDFY4 SLC2A1	5.20e-04	30	155	3	C0008073
Disease	Helicobacter Infections	PTPRZ1 PRKAA1	5.66e-04	7	155	2	C0079487
Disease	abnormal vaginal discharge smell	KCNJ6 MAP3K10	5.66e-04	7	155	2	EFO_0009408
Disease	polycystic liver disease (implicated_via_orthology)	HDAC6 PKD1	5.66e-04	7	155	2	DOID:0050770 (implicated_via_orthology)
Disease	monocyte count	CRYBG2 FN1 STAG1 DOCK8 SPTBN1 LCT SLC2A1 TTLL12 CD1A CD1B SLC22A4 PKD1 KCNN4 FCRL4 SLC41A1 AP3D1 CDK6	5.98e-04	1320	155	17	EFO_0005091
Disease	Pena-Shokeir syndrome type I	NUP88 GBE1	7.52e-04	8	155	2	C1276035
Disease	Autosomal Recessive Polycystic Kidney Disease	NPHP3 PKHD1	9.63e-04	9	155	2	C0085548
Disease	dipeptidase 2 measurement	DPEP2 DPEP3	1.20e-03	10	155	2	EFO_0801528
Disease	Lymphoma	DOCK8 CDK4 CDK6	1.22e-03	40	155	3	C0024299
Disease	diabetes mellitus (is_marker_for)	FN1 SLC2A1 MMP3	1.31e-03	41	155	3	DOID:9351 (is_marker_for)
Disease	high grade glioma (is_marker_for)	ASPM CDK4 CDK6	1.40e-03	42	155	3	DOID:3070 (is_marker_for)
Disease	Liver carcinoma	PGD SLC2A1 CCBE1 FANCI ASPM KIF14 CDK1 LILRB5 CDK4	1.50e-03	507	155	9	C2239176
Disease	Adenocarcinoma of large intestine	MAP2K4 CDK12 PAK5 RET	1.67e-03	96	155	4	C1319315
Disease	neurotic disorder	STAG1 GRM3 TENM3 BAIAP2	2.01e-03	101	155	4	EFO_0004257
Disease	melanoma	ERCC1 HDAC6 RET GRM3 EPHX3 CDK4	2.05e-03	248	155	6	C0025202
Disease	matrix metalloproteinase measurement	MMP3 LILRB5	2.06e-03	13	155	2	EFO_0004744
Disease	ascorbic acid 2-sulfate measurement	DEAF1 C16orf54	2.06e-03	13	155	2	EFO_0800169
Disease	Nephronophthisis	NPHP3 SLC41A1	2.06e-03	13	155	2	C0687120
Disease	cannabis dependence measurement	RET SLC35G1 PKHD1	2.07e-03	48	155	3	EFO_0008457
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	NPHP3 PKD1	2.39e-03	14	155	2	DOID:898 (implicated_via_orthology)
Disease	polycystic kidney disease (implicated_via_orthology)	HDAC6 PKD1	2.39e-03	14	155	2	DOID:0080322 (implicated_via_orthology)
Disease	Squamous cell carcinoma of the head and neck	CCNA2 CDK4 CDK6	2.60e-03	52	155	3	C1168401
Disease	pancreatic adenocarcinoma (is_implicated_in)	CDK4 CDK6	2.75e-03	15	155	2	DOID:4074 (is_implicated_in)
Disease	Autosomal recessive primary microcephaly	ASPM CDK6	2.75e-03	15	155	2	cv:C3711387
Disease	R-warfarin measurement	DOCK4 CACNA1C SMG1 STAG1 TBX18 ZFYVE26	2.84e-03	265	155	6	EFO_0803324
Disease	mean platelet volume	DOCK8 CDK12 NPEPPS SPTBN1 BCORL1 NUP88 ITGA2B FAM187B CCBE1 SLC22A4 KCNN4 ZNF324B CDK4	2.91e-03	1020	155	13	EFO_0004584
Disease	Chromosome Aberrations	ERCC1 CDK6	3.13e-03	16	155	2	C0008625
Disease	Autosome Abnormalities	ERCC1 CDK6	3.13e-03	16	155	2	C0004403
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	PKD1 PKHD1	3.13e-03	16	155	2	DOID:0110861 (implicated_via_orthology)
Disease	primary autosomal recessive microcephaly (is_implicated_in)	ASPM KIF14	3.13e-03	16	155	2	DOID:0070296 (is_implicated_in)
Disease	rheumatoid arthritis	STAG1 CDK12 TMEM151B NUP88 WDFY4 TPRG1 TET3 CDK6	3.16e-03	462	155	8	EFO_0000685
Disease	Glycogen storage disease	GBE1 GAA	3.54e-03	17	155	2	cv:C0017919
Disease	Inborn Errors of Metabolism	LDHB SLC2A1	3.54e-03	17	155	2	C0025521
Disease	matrix metalloproteinase 12 measurement	MMP3 LILRB5	3.97e-03	18	155	2	EFO_0010590
Disease	Meckel syndrome type 1	NPHP3 KIF14	3.97e-03	18	155	2	C3714506
Disease	myeloid white cell count	FN1 DNAH10 DOCK8 SPTBN1 LCT SLC2A1 TTLL12 DPEP2 SLC22A4 PKD1 GGA1 CDK6	4.03e-03	937	155	12	EFO_0007988
Disease	glomerulonephritis (is_marker_for)	FN1 MMP3	4.42e-03	19	155	2	DOID:2921 (is_marker_for)
Disease	Hereditary Diffuse Gastric Cancer	ERCC1 MARK1 PRKAA1 MUC6 EPHX3 CDK4	4.64e-03	293	155	6	C1708349
Disease	cholangiocarcinoma (is_marker_for)	HDAC6 PANX2 MUC6	4.69e-03	64	155	3	DOID:4947 (is_marker_for)
Disease	Malignant Neoplasms	ERCC1 RET CDK4 CDK6	4.72e-03	128	155	4	C0006826
Disease	glomerulonephritis (biomarker_via_orthology)	ITGA3 MMP3	4.90e-03	20	155	2	DOID:2921 (biomarker_via_orthology)
Disease	Stomach Neoplasms	ERCC1 MARK1 PRKAA1 MUC6 EPHX3 CDK4	4.95e-03	297	155	6	C0038356
Disease	Tinnitus	MAP3K8 SPTBN1 METTL25B PKHD1	4.99e-03	130	155	4	HP_0000360
Disease	Malignant neoplasm of stomach	ERCC1 MARK1 PRKAA1 MUC6 EPHX3 CDK4	5.19e-03	300	155	6	C0024623

Protein segments in the cluster

Peptide	Gene	Start	Entry
DGIPYRTVSEWLESI	EPHA1	911	P21709
LGLPWYVSATVISLA	SLC4A9	771	Q96Q91
LLLGEERYTPAIDVW	CDK12	906	Q9NYV4
GVDPYSRRSIWDLLL	ABCA4	1091	P78363
ISYPVERGLITSWED	ACTRT3	66	Q9BYD9
RLWSLTYEEELTTPL	ASB10	106	Q8WXI3
SLDTILSSYLLGQWP	FAM117A	91	Q9C073
WLILEAPGTRRYTLA	GRM3	706	Q14832
RDGEVILSDWSTYPE	FCRL4	231	Q96PJ5
LETIWLLLSYGADPT	BCORL1	1576	Q5H9F3
RSEDWYGSAVPLLTD	C16orf54	91	Q6UWD8
WTAISALEYGVPVTL	PGD	266	P52209
VLRYDGLITWDAPAI	CHRNA9	136	Q9UGM1
SYNRIGLLDSEWIPV	AMIGO2	76	Q86SJ2
RWSSLAEPGSAYLVV	ARAP2	1401	Q8WZ64
VTLWYRAPEVLLQSS	CDK6	181	Q00534
SGEARWTYPVLLVDD	ELP6	131	Q0PNE2
IILYWRNPTSIGSIV	CD1B	291	P29016
PLWLRIGLETTYGEL	ASPM	821	Q8IZT6
LWPRGTSEPEYTEIL	ATG2A	526	Q2TAZ0
EWYISILVELTRLEG	AP3D1	416	O14617
YVGLVLDETRDWPES	C17orf113	201	A0A1B0GUU1
VRSDVWSLGITLYEL	MAP2K4	286	P45985
AGLRISPEQWSSLLY	RC3H2	291	Q9HBD1
LLLWEAGSEAVRYSI	PCDHB5	21	Q9Y5E4
WTSTLRPAAELDYAI	RGS11	111	O94810
IPWLEEAVSLFRGSY	P4HA3	201	Q7Z4N8
GSEWTSVLLYVPSII	ANO10	351	Q9NW15
SRLPYGTEVDIWSLG	PAK5	616	Q9P286
DITRVLLWRYTSIPT	FANCI	876	Q9NVI1
VDISIPGRYNLTLIW	MUC6	966	Q6W4X9
IPYRESVLTWLLKES	KIF14	651	Q15058
ESRDIPIWGTLIQYI	LPCAT1	156	Q8NF37
VLLWELLTGEVPYRE	MAP3K10	291	Q02779
LWLIPITFLTIGYGD	KCNN4	241	O15554
TISPAYLLWDLSAIS	GNPTAB	296	Q3T906
RYGESILPTTLTTLW	SLC2A1	51	P11166
TWLVLSEIYPVEIRG	SLC2A10	431	O95528
ITSEILWGYRFTPVL	KCNJ6	326	P48051
LWGYRFTPVLTLEDG	KCNJ6	331	P48051
ELVSSWLQSRPDLYL	HEMK1	301	Q9Y5R4
GITLDLVSRLVYWAD	LRP1	371	Q07954
HITDWYPTLISLAEG	ARSJ	376	Q5FYB0
YDIWETISEGLRSPR	ARSJ	401	Q5FYB0
WEEVTPLTFSRLYEG	MMP3	141	P08254
DILPSADGTWYLRAT	CD1A	251	P06126
LILAWSPEEAGRYLE	ERCC1	196	P07992
PWLSSVRYGTVEDLL	MAP3K8	71	P41279
LGTLVLGLEWPYEVS	ITGA3	811	P26006
VLSYHRLPAGVSWLE	CSNKA2IP	671	A0A1B0GTH6
ATEGTRPGLEELYWL	NRL	61	P54845
SLTSETEWVGYPFRL	MED23	1176	Q9ULK4
LVDDVWLYVSGGRTP	MEGF8	341	Q7Z7M0
AYVDLRPWLLEIGFS	NOD1	96	Q9Y239
ISWSRILPDGTTRYI	LCT	1451	P09848
ASLYVLGTATRWPLA	MTFP1	106	Q9UDX5
ISGIRPTYILRWTVE	LAS1L	411	Q9Y4W2
LELLYSWTVGLPEEV	GGA1	116	Q9UJY5
WSILYLLLSLSEDPR	TUBGCP3	91	Q96CW5
TLWCQGPLETEEYRL	LILRB5	46	O75023
EVVRYRSVWPLTLLA	METTL25B	76	Q96FB5
TSLLVTWERPRVVYD	PTPRZ1	326	P23471
LEVTLAGWEPRRYSV	PCDHB15	21	Q9Y5E8
CGESPVWRIYVTLLS	GPR42	251	O15529
SLLTYGRRIPLAEWE	UQCRC1	416	P31930
IAEWLPSYIPTDLLE	CASKIN2	551	Q8WXE0
ITLLRDPVSRYLSEW	HS6ST1	181	O60243
LVDRYLSWFLPTEGS	SMPD4	226	Q9NXE4
WIGSLSDAELLDYLP	PIK3C2B	906	O00750
ATLPLSYRLGTWVLV	FAM171A2	81	A8MVW0
SYRLGTWVLVTAARP	FAM171A2	86	A8MVW0
ITSKSGEILYRISPW	GBE1	146	Q04446
VSTFEGWPELLYRSI	CACNA1C	1131	Q13936
GWPELLYRSIDSHTE	CACNA1C	1136	Q13936
LWVERTSLYLVQSLP	DOCK4	1436	Q8N1I0
TSLYLVQSLPGISRW	DOCK4	1441	Q8N1I0
SVETLLGYSWLPILL	DOCK8	661	Q8NF50
TAAILTSLWLLEQPY	CPLANE1	1781	Q9H799
TLWYRAPELLLGTTT	CDK10	201	Q15131
VTLWYRAPEVLLQST	CDK4	176	P11802
LVNGLELSEPRSWLY	DEAF1	441	O75398
RWTPLNSSTIIGYRI	FN1	1286	P02751
VWTIGLELEYLTSRF	DHX57	271	Q6P158
LLALGHTWTYREEPE	CCBE1	26	Q6UXH8
GSLRRVVWDYSTPEI	CRYBG2	1061	Q8N1P7
LLWAIHYEESPGVRL	HEATR4	801	Q86WZ0
PALSWRSTGGILDVY	GAA	326	P10253
TTPTLLLWGEKDTYL	EPHX3	296	Q9H6B9
PEVDVWSLGVILYTL	MARK1	236	Q9P0L2
STYPVLIEELLSRGW	DPEP2	366	Q9H4A9
ITILRDPVSRYLSEW	HS6ST2	321	Q96MM7
VDILTYVTWKLSGLP	LDHB	141	P07195
YLGEVLVWSSRLRPE	FAM187B	181	Q17R55
PVLEALYRLQWTSTD	DDX10	126	Q13206
YPVLIEELLSRSWSE	DPEP3	376	Q9H4B8
ILTWPVLQSRTGLVY	HDAC6	471	Q9UBN7
SWPESLIRKTGYTLE	CCNA2	371	P20248
ELYGILDPTTRDWTD	DNAH10	2151	Q8IVF4
VLGLVSGLSLEPVYW	EFNB3	21	Q15768
LSALIEIPAYITAWL	SLC22A4	376	Q9H015
EIPAYITAWLLLRTL	SLC22A4	381	Q9H015
YLREDGALSIWPLTQ	PPP4R1L	281	Q9P1A2
WGLVTYRETALLIDP	NPEPPS	321	P55786
ILGSRYSTPIDIWSF	DYRK3	381	O43781
LVPIIEGGSYRVWSD	PKD1	2256	P98161
YVPALGWEFLASTRL	PANX2	136	Q96RD6
YARSILTVPWVELGG	OSBPL11	571	Q9BXB4
KSWDSRIDLIPSLYV	NUP88	351	Q99567
LDLGWPDTIAYRGVT	FAM83G	131	A6ND36
DLELPSWLTTGNYRI	GM2A	156	P17900
SLPTQTITIELWGYE	SUSD2	186	Q9UGT4
WLGYSELGPIKSLRT	SCN4A	1116	P35499
LGSWLVPFAYLTVLD	POMT2	151	Q9UKY4
LLAEGITWVLVYRTD	TMCO1	71	Q9UM00
ALLTLSWPLRVLAEY	TMEM151B	306	Q8IW70
AWETVRLEYLEGPTV	NPHP3	826	Q7Z494
IIVLTPDYILRRGWS	IL1RAPL2	471	Q9NP60
PDYILRRGWSIFELE	IL1RAPL2	476	Q9NP60
ALPATVWSLGILLYD	PIM2	216	Q9P1W9
ASYILRLEEISPWLA	SMG1	2086	Q96Q15
WLERIPYTALVGDIT	SLITRK3	246	O94933
EYTVELRGATLSWAP	ARHGAP27	556	Q6ZUM4
RGLYDVALPWLSSVF	SH3TC1	516	Q8TE82
ATREVLYSGWEPVII	SLC41A1	311	Q8IVJ1
VTALEWDPLSTDYLL	WDR17	226	Q8IZU2
SDWTLDTIYPVLDLL	WDR17	1126	Q8IZU2
LELTEATPGYRWQIV	PKHD1	341	P08F94
VADIFSSYRPGILLW	ITGA2B	231	P08514
WGVELLPSSLQSRLY	PPP1R15B	181	Q5SWA1
AYVSLLDLTPTILDW	SGSH	311	P51688
WSSEYVRGLGALLPT	URB1	1176	O60287
LTQVYGIPEERLWIS	AARS2	156	Q5JTZ9
TELLERLPSYDWLLQ	SSUH2	26	Q9Y2M2
AWLLGQEPYLSSREI	SPTBN1	2031	Q01082
ISGRLYAGPEVDIWS	PRKAA1	196	Q13131
RLLPSELTLWVDPYE	BTG1	96	P62324
LITLLVPEARDGWHY	BAIAP2	401	Q9UQB8
TLWYRSPEVLLGSAR	CDK1	166	P06493
WYLAGEARLTVVPVS	PNMT	221	P11086
PTGVSVIYWERLLLG	ZNF324	136	O75467
VDVLAEWGSLYVLTR	VPS11	331	Q9H270
ATTWGYPVALLLLVA	ZP1	6	P60852
TADPLWALVDVYGLT	NEURL1	196	O76050
LVESYAFWRPSLRTL	TBX18	341	O95935
FTPDSLDIRWGIRYL	THAP5	61	Q7Z6K1
LRIYWGSPEEQSLLS	TPRG1	166	Q6ZUI0
IWRLGPTYLFEEAIS	WDFY4	1231	Q6ZS81
VWLPLISYRNSLVTG	STAG1	1041	Q8WVM7
LLRIAYDTSGHPTLW	TENM3	1796	Q9P273
DYDILAGRWTTPDIE	TENM3	2356	Q9P273
FWYIIDTERLERTGP	TMEM114	31	B3SHH9
SYWLQLRSEPDGISL	MPL	251	P40238
LAWEGIPRSLGDTLY	TET3	926	O43151
DYVWPRATSELILLP	WDR6	6	Q9NNW5
LYVWTLVAPLVLTSR	SERINC3	456	Q13530
VAYTLLWPLRDLDTG	TTLL12	221	Q14166
YLTADSPSLLEEWIR	PLEKHH1	651	Q9ULM0
TEAWDFLRRLGVYPT	NSMCE3	196	Q96MG7
RTYPGLVNWLFVLTE	nan	36	Q6ZVL8
VRRYTSTLLPGDTWA	RET	311	P07949
SVIILSVLGEWSLPY	SLC35G1	266	Q2M3R5
YILPRLSGLIEDEWI	TARBP1	1361	Q13395
TYRDWVSLLILGPQE	VSIG10L	716	Q86VR7
EGEPTLRSLLWYDET	TEX15	1711	Q9BXT5
SIDPTLESWGKYLIA	ZFYVE26	2226	Q68DK2
YTWRGLSLDSPIAVL	ZMYND15	466	Q9H091
ESLADIVLWGALYPL	MARS1	141	P56192
PTGVSVIYWERLLLG	ZNF324B	136	Q6AW86