Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	MAP kinase kinase kinase activity	MAP3K3 MAP3K4 MAP3K2 MAP3K19	8.43e-06	27	97	4	GO:0004709
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH2 DNAH17 DNAH8	8.60e-05	18	97	3	GO:0008569
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH2 DNAH17 DNAH8	3.33e-04	28	97	3	GO:0051959
GeneOntologyMolecularFunction	double-stranded RNA adenosine deaminase activity	ADARB1 ADARB2	3.46e-04	6	97	2	GO:0003726
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	AQP7P3 SLCO1B7 SLC18A2 SLC10A6	3.75e-04	70	97	4	GO:1901618
GeneOntologyMolecularFunction	microtubule motor activity	KIF23 DNAH2 DNAH17 DNAH8	3.75e-04	70	97	4	GO:0003777
GeneOntologyMolecularFunction	tRNA-specific adenosine deaminase activity	ADARB1 ADARB2	6.42e-04	8	97	2	GO:0008251
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH2 DNAH17 DNAH8	7.66e-04	37	97	3	GO:0045505
GeneOntologyCellularComponent	axonemal dynein complex	DNAH2 DNAH17 DNAH8	2.07e-04	25	97	3	GO:0005858
GeneOntologyCellularComponent	CCR4-NOT core complex	CNOT8 CNOT7	3.16e-04	6	97	2	GO:0030015
HumanPheno	Absent sperm flagella	DNAH2 DNAH17 DNAH8 BRWD1	2.08e-05	28	31	4	HP:0032558
HumanPheno	Short sperm flagella	DNAH2 DNAH17 DNAH8 BRWD1	4.06e-05	33	31	4	HP:0032559
Domain	WD40_repeat_dom	NWD1 TBL1Y NBEAL1 APAF1 GEMIN5 ARHGEF17 WDR11 FBXW11 BRWD1	2.05e-05	297	95	9	IPR017986
Domain	WD40_repeat_CS	NWD1 TBL1Y APAF1 GEMIN5 WDR11 FBXW11 BRWD1	2.05e-05	164	95	7	IPR019775
Domain	-	NWD1 TBL1Y NBEAL1 APAF1 GEMIN5 ARHGEF17 WDR11 FBXW11 BRWD1	5.00e-05	333	95	9	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	NWD1 TBL1Y NBEAL1 APAF1 GEMIN5 ARHGEF17 WDR11 FBXW11 BRWD1	5.24e-05	335	95	9	IPR015943
Domain	WD40	NWD1 TBL1Y NBEAL1 APAF1 GEMIN5 WDR11 FBXW11 BRWD1	5.27e-05	259	95	8	PF00400
Domain	WD40	NWD1 TBL1Y NBEAL1 APAF1 GEMIN5 WDR11 FBXW11 BRWD1	6.70e-05	268	95	8	SM00320
Domain	WD40_repeat	NWD1 TBL1Y NBEAL1 APAF1 GEMIN5 WDR11 FBXW11 BRWD1	7.43e-05	272	95	8	IPR001680
Domain	WD_REPEATS_1	NWD1 TBL1Y NBEAL1 APAF1 GEMIN5 WDR11 FBXW11 BRWD1	8.65e-05	278	95	8	PS00678
Domain	WD_REPEATS_2	NWD1 TBL1Y NBEAL1 APAF1 GEMIN5 WDR11 FBXW11 BRWD1	8.87e-05	279	95	8	PS50082
Domain	WD_REPEATS_REGION	NWD1 TBL1Y NBEAL1 APAF1 GEMIN5 WDR11 FBXW11 BRWD1	8.87e-05	279	95	8	PS50294
Domain	-	GTF2IRD2B GTF2IRD2	1.53e-04	4	95	2	3.90.1460.10
Domain	GTF2I	GTF2IRD2B GTF2IRD2	1.53e-04	4	95	2	PS51139
Domain	GTF2I	GTF2IRD2B GTF2IRD2	1.53e-04	4	95	2	PF02946
Domain	GTF2I	GTF2IRD2B GTF2IRD2	1.53e-04	4	95	2	IPR004212
Domain	CAF1	CNOT8 CNOT7	2.53e-04	5	95	2	PF04857
Domain	RNase_CAF1	CNOT8 CNOT7	2.53e-04	5	95	2	IPR006941
Domain	ADEAMc	ADARB1 ADARB2	3.79e-04	6	95	2	SM00552
Domain	A_deamin	ADARB1 ADARB2	3.79e-04	6	95	2	PF02137
Domain	A_DEAMIN_EDITASE	ADARB1 ADARB2	3.79e-04	6	95	2	PS50141
Domain	A_deamin	ADARB1 ADARB2	3.79e-04	6	95	2	IPR002466
Domain	RNaseH-like_dom	CNOT8 GTF2IRD2B CNOT7 GTF2IRD2	4.22e-04	69	95	4	IPR012337
Domain	DHC_N1	DNAH2 DNAH8	7.03e-04	8	95	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH2 DNAH8	7.03e-04	8	95	2	IPR013594
Domain	Znf_SWIM	ZSWIM5 ZSWIM6	9.00e-04	9	95	2	IPR007527
Domain	ZF_SWIM	ZSWIM5 ZSWIM6	9.00e-04	9	95	2	PS50966
Domain	G-protein_beta_WD-40_rep	TBL1Y APAF1 GEMIN5 FBXW11	9.28e-04	85	95	4	IPR020472
Domain	F-box-like	FBXL17 FBXO17 FBXW11	1.45e-03	44	95	3	PF12937
Domain	Kinase-like_dom	CDKL2 NTRK2 TEK MAP3K3 MAP3K4 DST CDK3 MAP3K2 MAP3K19	1.76e-03	542	95	9	IPR011009
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DNAH8	2.24e-03	14	95	2	IPR024317
Domain	PB1	MAP3K3 MAP3K2	2.24e-03	14	95	2	SM00666
Domain	Dynein_HC_stalk	DNAH2 DNAH8	2.24e-03	14	95	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH2 DNAH8	2.24e-03	14	95	2	IPR013602
Domain	DHC_N2	DNAH2 DNAH8	2.24e-03	14	95	2	PF08393
Domain	MT	DNAH2 DNAH8	2.24e-03	14	95	2	PF12777
Domain	AAA_8	DNAH2 DNAH8	2.24e-03	14	95	2	PF12780
Domain	PB1	MAP3K3 MAP3K2	2.24e-03	14	95	2	PF00564
Domain	ATPase_dyneun-rel_AAA	DNAH2 DNAH8	2.24e-03	14	95	2	IPR011704
Domain	PB1	MAP3K3 MAP3K2	2.24e-03	14	95	2	PS51745
Domain	AAA_5	DNAH2 DNAH8	2.24e-03	14	95	2	PF07728
Domain	PB1_dom	MAP3K3 MAP3K2	2.24e-03	14	95	2	IPR000270
Domain	FBOX	FBXL17 FBXO17 FBXW11	2.35e-03	52	95	3	SM00256
Domain	PROTEIN_KINASE_ATP	CDKL2 NTRK2 TEK MAP3K3 MAP3K4 CDK3 MAP3K2 MAP3K19	2.35e-03	459	95	8	PS00107
Domain	S_TKc	CDKL2 TEK MAP3K3 MAP3K4 CDK3 MAP3K2 MAP3K19	2.38e-03	359	95	7	SM00220
Domain	DHC_fam	DNAH2 DNAH8	2.57e-03	15	95	2	IPR026983
Domain	Dynein_heavy_dom	DNAH2 DNAH8	2.57e-03	15	95	2	IPR004273
Domain	Dynein_heavy	DNAH2 DNAH8	2.57e-03	15	95	2	PF03028
Domain	Protein_kinase_ATP_BS	CDKL2 NTRK2 TEK MAP3K4 CDK3 MAP3K2 MAP3K19	3.21e-03	379	95	7	IPR017441
Domain	Prot_kinase_dom	CDKL2 NTRK2 TEK MAP3K3 MAP3K4 CDK3 MAP3K2 MAP3K19	3.47e-03	489	95	8	IPR000719
Domain	PROTEIN_KINASE_DOM	CDKL2 NTRK2 TEK MAP3K3 MAP3K4 CDK3 MAP3K2 MAP3K19	3.64e-03	493	95	8	PS50011
Domain	DSRM	ADARB1 ADARB2	4.14e-03	19	95	2	SM00358
Domain	Apc4_WD40_dom	NWD1 GEMIN5	4.58e-03	20	95	2	IPR024977
Domain	ANAPC4_WD40	NWD1 GEMIN5	4.58e-03	20	95	2	PF12894
Domain	dsrm	ADARB1 ADARB2	4.58e-03	20	95	2	PF00035
Domain	F-box	FBXL17 FBXO17 FBXW11	4.83e-03	67	95	3	PF00646
Domain	FA58C	RS1 DCBLD2	5.05e-03	21	95	2	SM00231
Domain	DS_RBD	ADARB1 ADARB2	5.05e-03	21	95	2	PS50137
Domain	FA58C_3	RS1 DCBLD2	5.05e-03	21	95	2	PS50022
Domain	FA58C_1	RS1 DCBLD2	5.05e-03	21	95	2	PS01285
Domain	FA58C_2	RS1 DCBLD2	5.05e-03	21	95	2	PS01286
Pubmed	MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42.	MAP3K3 MAP3K4 MAP3K2	4.31e-07	6	98	3	9305638
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH2 DNAH17 DNAH8	7.53e-07	7	98	3	31178125
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	IQSEC3 ZSWIM5 SYNE1 ARHGEF12 ZSWIM6 ARHGEF17 MAP3K4 PLCL2 PDZD2	2.37e-06	407	98	9	12693553
Pubmed	Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes.	KIF23 CNOT8 PTPRC CNOT7	6.72e-06	43	98	4	30733279
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH2 DNAH17 DNAH8	7.72e-06	14	98	3	9373155
Pubmed	The kinases MEKK2 and MEKK3 regulate transforming growth factor-β-mediated helper T cell differentiation.	MAP3K3 MAP3K2	7.86e-06	2	98	2	21333552
Pubmed	Conservation of the deadenylase activity of proteins of the Caf1 family in human.	CNOT8 CNOT7	7.86e-06	2	98	2	15769875
Pubmed	Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells.	XPC REV1	7.86e-06	2	98	2	19332561
Pubmed	Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase.	MAP3K3 MAP3K2	7.86e-06	2	98	2	8621389
Pubmed	Error-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasia.	XPC REV1	7.86e-06	2	98	2	20007784
Pubmed	CNOT7 Outcompetes Its Paralog CNOT8 for Integration into The CCR4-NOT Complex.	CNOT8 CNOT7	7.86e-06	2	98	2	35248544
Pubmed	The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation.	CNOT8 CNOT7	7.86e-06	2	98	2	19605561
Pubmed	Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions.	XPC REV1	7.86e-06	2	98	2	28827409
Pubmed	The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste.	UGT2A2 UGT2A1	7.86e-06	2	98	2	35039640
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	7.86e-06	2	98	2	15388857
Pubmed	Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis.	UGT2A2 UGT2A1	7.86e-06	2	98	2	11376859
Pubmed	RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.	ADARB1 ADARB2	7.86e-06	2	98	2	20011587
Pubmed	Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase.	UGT2A2 UGT2A1	7.86e-06	2	98	2	10359671
Pubmed	SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital Glaucoma.	TEK SVEP1	7.86e-06	2	98	2	33027505
Pubmed	MAP3Ks as central regulators of cell fate during development.	MAP3K3 MAP3K4 MAP3K2	9.63e-06	15	98	3	18855897
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	NTRK2 TFDP3 FBXO17 GTF2IRD2 TRIM36 CDK3 MAP3K2 FBXW11	1.08e-05	372	98	8	22939624
Pubmed	Genetic variants of Y chromosome are associated with a protective lipid profile in black men.	TBL1Y USP9Y	2.35e-05	3	98	2	18511697
Pubmed	Skin CD4(+) memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation.	PTPRC CCR8	2.35e-05	3	98	2	27160938
Pubmed	Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta.	MAP3K3 MAP3K2	2.35e-05	3	98	2	10085062
Pubmed	WNK1 activates ERK5 by an MEKK2/3-dependent mechanism.	MAP3K3 MAP3K2	2.35e-05	3	98	2	14681216
Pubmed	NAD(P)H oxidase and eNOS play differential roles in cytomegalovirus infection-induced microvascular dysfunction.	PTPRC NOS3	2.35e-05	3	98	2	22033010
Pubmed	Endothelial nitric oxide synthase regulates white matter changes via the BDNF/TrkB pathway after stroke in mice.	NTRK2 NOS3	2.35e-05	3	98	2	24236179
Pubmed	The Human UDP-glucuronosyltransferase UGT2A1 and UGT2A2 enzymes are highly active in bile acid glucuronidation.	UGT2A2 UGT2A1	2.35e-05	3	98	2	23756265
Pubmed	The BTG4 and CAF1 complex prevents the spontaneous activation of eggs by deadenylating maternal mRNAs.	CNOT8 CNOT7	2.35e-05	3	98	2	27605379
Pubmed	CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells.	CNOT8 CNOT7	2.35e-05	3	98	2	20065043
Pubmed	Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	2.35e-05	3	98	2	15100712
Pubmed	The CCR4-NOT complex suppresses untimely translational activation of maternal mRNAs.	CNOT8 CNOT7	2.35e-05	3	98	2	37767629
Pubmed	Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3.	MAP3K3 MAP3K2	2.35e-05	3	98	2	14661019
Pubmed	Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3.	UGT2A2 UGT2A1	2.35e-05	3	98	2	19858781
Pubmed	The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4-Not nuclease module.	CNOT8 CNOT7	2.35e-05	3	98	2	25944446
Pubmed	Frequent loss of BTG1 activity and impaired interactions with the Caf1 subunit of the Ccr4-Not deadenylase in non-Hodgkin lymphoma.	CNOT8 CNOT7	2.35e-05	3	98	2	33021411
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SYNE1 DST DNAH17	2.39e-05	20	98	3	21689717
Pubmed	Mekk3 is essential for early embryonic cardiovascular development.	TEK MAP3K3 MAP3K2	2.78e-05	21	98	3	10700190
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PMPCB APLP2 PTPRC SSH1 WDR11 PLCL2 CPSF1 INTS4 TRIM36 NEURL4 FBXW11 SYMPK	3.99e-05	1049	98	12	27880917
Pubmed	Functional proteomics mapping of a human signaling pathway.	TENT5A APLP2 XPC SVEP1 DST PTPRC PLCL2 SPRTN UHRF2	4.57e-05	591	98	9	15231748
Pubmed	Relationships of the antiproliferative proteins BTG1 and BTG2 with CAF1, the human homolog of a component of the yeast CCR4 transcriptional complex: involvement in estrogen receptor alpha signaling pathway.	CNOT8 CNOT7	4.70e-05	4	98	2	11136725
Pubmed	Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding.	CNOT8 CNOT7	4.70e-05	4	98	2	11747467
Pubmed	MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function.	MAP3K3 MAP3K2	4.70e-05	4	98	2	29662197
Pubmed	Low expression of CD39(+) /CD45RA(+) on regulatory T cells (Treg ) cells in type 1 diabetic children in contrast to high expression of CD101(+) /CD129(+) on Treg cells in children with coeliac disease.	PTPRC CD101	4.70e-05	4	98	2	25421756
Pubmed	Human carbon catabolite repressor protein (CCR4)-associative factor 1: cloning, expression and characterization of its interaction with the B-cell translocation protein BTG1.	CNOT8 CNOT7	4.70e-05	4	98	2	9820826
Pubmed	TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.	GTF2IRD2B GTF2IRD2	4.70e-05	4	98	2	17823943
Pubmed	Evolution of general transcription factors.	GTF2IRD2B GTF2IRD2	4.70e-05	4	98	2	23229069
Pubmed	GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.	GTF2IRD2B GTF2IRD2	4.70e-05	4	98	2	22899722
Pubmed	MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway.	MAP3K3 MAP3K2	4.70e-05	4	98	2	11073940
Pubmed	Developmental cell death is enhanced in the cerebral cortex of mice lacking the brain vesicular monoamine transporter.	NTRK2 SLC18A2	4.70e-05	4	98	2	17287506
Pubmed	The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex.	CNOT8 CNOT7	4.70e-05	4	98	2	23236473
Pubmed	Quantitative characterization of Tob interactions provides the thermodynamic basis for translation termination-coupled deadenylase regulation.	CNOT8 CNOT7	4.70e-05	4	98	2	20595394
Pubmed	Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.	GTF2IRD2B GTF2IRD2	4.70e-05	4	98	2	21328569
Pubmed	Somatic mutation spectrum of a Chinese cohort of pediatrics with vascular malformations.	TEK MAP3K3	4.70e-05	4	98	2	37658401
Pubmed	Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.	PTPRC CD101 PLCL2	4.77e-05	25	98	3	19898481
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	CCPG1 SYNE1 DNAH2 ZNF529 DST NEURL4	5.34e-05	233	98	6	37704626
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KIF23 GEMIN5 XPC ADARB1 PTPRC SSH1 CPSF1 EXOC2 ESPL1 SYMPK	6.76e-05	774	98	10	15302935
Pubmed	PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway.	MAP3K3 MAP3K2	7.82e-05	5	98	2	12912994
Pubmed	Nurr1 regulates dopamine synthesis and storage in MN9D dopamine cells.	DDC SLC18A2	7.82e-05	5	98	2	12915123
Pubmed	Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase.	CNOT8 CNOT7	7.82e-05	5	98	2	21336257
Pubmed	The HIV-1 gp120 inhibits the binding of adenosine deaminase to CD26 by a mechanism modulated by CD4 and CXCR4 expression.	ADARB1 ADARB2	7.82e-05	5	98	2	10899322
Pubmed	Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily.	UGT2A2 UGT2A1	7.82e-05	5	98	2	16141793
Pubmed	HIV-1 envelope gp120 and viral particles block adenosine deaminase binding to human CD26.	ADARB1 ADARB2	7.82e-05	5	98	2	9330696
Pubmed	The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex.	CNOT8 CNOT7	7.82e-05	5	98	2	22977175
Pubmed	Cnot8 eliminates naïve regulation networks and is essential for naïve-to-formative pluripotency transition.	CNOT8 CNOT7	7.82e-05	5	98	2	35390160
Pubmed	Adenosine deaminase binding to human CD26 is inhibited by HIV-1 envelope glycoprotein gp120 and viral particles.	ADARB1 ADARB2	7.82e-05	5	98	2	9103436
Pubmed	Relaxin exerts two opposite effects on mechanical activity and nitric oxide synthase expression in the mouse colon.	RLN2 NOS3	7.82e-05	5	98	2	22932783
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	IQSEC3 KIF23 TBL1Y SYNE1 NTRK2 ZBTB22 ARHGEF12 DST SSH1 KCNJ4 NEURL4	8.66e-05	963	98	11	28671696
Pubmed	Cerebral cavernous malformation 2 protein promotes smad ubiquitin regulatory factor 1-mediated RhoA degradation in endothelial cells.	MAP3K3 MAP3K2	1.17e-04	6	98	2	19318350
Pubmed	hCAF1, a new regulator of PRMT1-dependent arginine methylation.	CNOT8 CNOT7	1.17e-04	6	98	2	17264152
Pubmed	PB1 domain interaction of p62/sequestosome 1 and MEKK3 regulates NF-kappaB activation.	MAP3K3 MAP3K2	1.17e-04	6	98	2	19903815
Pubmed	Pet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxiety-like and aggressive behavior.	DDC SLC18A2	1.17e-04	6	98	2	12546819
Pubmed	ARF stimulates XPC to trigger nucleotide excision repair by regulating the repressor complex of E2F4.	TFDP3 XPC	1.17e-04	6	98	2	19644500
Pubmed	Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability.	CNOT8 CNOT7	1.17e-04	6	98	2	31924127
Pubmed	Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency.	DDC SLC18A2	1.17e-04	6	98	2	17592014
Pubmed	MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitment.	CNOT8 CNOT7	1.17e-04	6	98	2	20595389
Pubmed	CNOT7/hCAF1 is involved in ICAM-1 and IL-8 regulation by tristetraprolin.	CNOT8 CNOT7	1.17e-04	6	98	2	25038453
Pubmed	Comodulation of CXCR4 and CD26 in human lymphocytes.	ADARB1 ADARB2	1.17e-04	6	98	2	11278278
Pubmed	Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons.	DDC SLC18A2	1.17e-04	6	98	2	14622207
Pubmed	Reprogramming of microRNAs by adenosine-to-inosine editing and the selective elimination of edited microRNA precursors in mouse oocytes and preimplantation embryos.	ADARB1 ADARB2	1.64e-04	7	98	2	23571754
Pubmed	Defects of the chorioallantoic placenta in mouse RXRalpha null fetuses.	RBP1 TEK	1.64e-04	7	98	2	9356169
Pubmed	Complex protein interactions within the human polyadenylation machinery identify a novel component.	CPSF1 SYMPK	1.64e-04	7	98	2	10669729
Pubmed	14-3-3 proteins interact with specific MEK kinases.	MAP3K3 MAP3K2	1.64e-04	7	98	2	9452471
Pubmed	Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.	CNOT8 CNOT7	1.64e-04	7	98	2	10637334
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH2 DNAH8	1.64e-04	7	98	2	9256245
Pubmed	Postnatal maintenance of the 5-Ht1a-Pet1 autoregulatory loop by serotonin in the raphe nuclei of the brainstem.	DDC SLC18A2	1.64e-04	7	98	2	24972638
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	KIF23 APLP2 ARHGEF17 MAP3K2	2.04e-04	102	98	4	15778465
Pubmed	Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons.	DDC SLC18A2	2.18e-04	8	98	2	20016108
Pubmed	TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis.	MAP3K3 MAP3K2	2.18e-04	8	98	2	15001576
Pubmed	Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment.	CNOT8 CNOT7	2.79e-04	9	98	2	21078877
Pubmed	Flow activates ERK1/2 and endothelial nitric oxide synthase via a pathway involving PECAM1, SHP2, and Tie2.	TEK NOS3	2.79e-04	9	98	2	15985432
Pubmed	Distinct expression patterns of the subunits of the CCR4-NOT deadenylase complex during neural development.	CNOT8 CNOT7	2.79e-04	9	98	2	21741365
Pubmed	Kelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates Skeletal Muscle Myogenesis through the E2F1-DP1 Complex.	APAF1 TFDP3	2.79e-04	9	98	2	25940086
Pubmed	Lmx1b Influences Correct Post-mitotic Coding of Mesodiencephalic Dopaminergic Neurons.	DDC SLC18A2	2.79e-04	9	98	2	30930745
Pubmed	Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport.	NTRK2 DST	2.79e-04	9	98	2	17287360
Pubmed	Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the receptor protein of CRL2Prame complex.	FBXL17 FBXO17 FBXW11	3.42e-04	48	98	3	33504946
Pubmed	Limited associations of dopamine system genes with alcohol dependence and related traits in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD).	DDC SLC18A2	3.48e-04	10	98	2	21083670
Pubmed	Defective lung vascular development and fatal respiratory distress in endothelial NO synthase-deficient mice: a model of alveolar capillary dysplasia?	TEK NOS3	3.48e-04	10	98	2	15016731
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	TENT5A ZBTB22 APLP2 DST KCNJ4 SPRTN	3.64e-04	332	98	6	37433992
Pubmed	The DNA sequence and analysis of human chromosome 6.	ENPP3 SYNE1 TENT5A ZBTB22 DST EXOC2 DNAH8 GABBR1	3.84e-04	622	98	8	14574404
Cytoband	9p24.1	CDC37L1 RLN2 UHRF2	5.54e-05	34	99	3	9p24.1
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	MAP3K3 MAP3K4 MAP3K2 MAP3K19	2.72e-06	24	75	4	654
GeneFamily	WD repeat domain containing	NWD1 TBL1Y NBEAL1 APAF1 GEMIN5 WDR11 FBXW11 BRWD1	1.27e-05	262	75	8	362
GeneFamily	Dyneins, axonemal	DNAH2 DNAH17 DNAH8	4.47e-05	17	75	3	536
GeneFamily	Adenosine deaminases acting on RNA	ADARB1 ADARB2	4.68e-04	8	75	2	1303
GeneFamily	Zinc fingers SWIM-type\|Mitogen-activated protein kinase kinase kinases	ZSWIM5 ZSWIM6	6.00e-04	9	75	2	90
GeneFamily	CCR4-NOT transcription complex	CNOT8 CNOT7	9.12e-04	11	75	2	1023
GeneFamily	Fibronectin type III domain containing	TEK PTPRC MYOM2 TRIM36	4.41e-03	160	75	4	555
GeneFamily	Cyclin dependent kinases	CDKL2 CDK3	5.17e-03	26	75	2	496
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ENPP3 TEK PTPRC CD101 CCR8 CD180	5.86e-03	394	75	6	471
GeneFamily	UDP glucuronosyltransferases	UGT2A2 UGT2A1	7.77e-03	32	75	2	363
Coexpression	GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_UP	APLP2 ADARB1 GABBR1	6.15e-06	10	99	3	M13976
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	APAF1 ZBTB22 DST SLC18A2 GTF2IRD2 TXNDC16	2.64e-06	175	99	6	da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CDKL2 ZSWIM5 CECR2 PTGFR DCBLD2 PDZD2	3.42e-06	183	99	6	6847c1252d6bb105524f812658112517fd351eab
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-BMP_responsible_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	NWD1 APLP2 PTPRC OSBPL1A GALNT5 MAP3K19	5.69e-06	200	99	6	5fb90118d3abc28d72bc483e68317255090a04c7
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	ZSWIM6 RLN2 DNAH17 CD180 NEURL4	2.51e-05	155	99	5	15bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	RBP1 APAF1 ADARB1 SVEP1 SLC10A6	3.28e-05	164	99	5	519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADARB1 ZNF529 PTPRC CD101 PLCL2	3.79e-05	169	99	5	8caf7996796a2e2716e3855de855c903d6126bf2
ToppCell	facs-Heart-LV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQSEC3 C3orf62 ZSWIM5 ARHGEF17 BCAR3	4.35e-05	174	99	5	a0a059bb2a64d7011e206db2ebcdf3eb655a925a
ToppCell	facs-Heart-LV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQSEC3 C3orf62 ZSWIM5 ARHGEF17 BCAR3	4.35e-05	174	99	5	7cd6f9103133f8d7b90f9ff4b3b0b078cf554542
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	APAF1 ZBTB22 DST SLC18A2 TXNDC16	4.47e-05	175	99	5	334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Lymphocytic-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 PTPRC CD101 CCR8 TRIM36	4.60e-05	176	99	5	096cbcefd9dcbaee660568998ba210253b58501e
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Lymphocytic\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 PTPRC CD101 CCR8 TRIM36	4.60e-05	176	99	5	90198fb79e8b08e9e7df538cbc05ad7141e78517
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTGFR ADARB2 PTPRC PLCL2 PDZD2	4.85e-05	178	99	5	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	IQSEC3 NTRK2 FBXL17 GTF2IRD2 REV1	4.85e-05	178	99	5	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ACADSB RBP1 ADARB1 SVEP1 SLC10A6	4.98e-05	179	99	5	b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 CD101 CCR8 TRIM36 NEURL4	5.25e-05	181	99	5	8a8061725e718c89a4c751a415120c5312acc757
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENT5A NTRK2 TEK SVEP1 SLC10A6	5.53e-05	183	99	5	5cfcd589a480e67654d3d94e71916f122150db10
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENT5A NTRK2 TEK SVEP1 SLC10A6	5.53e-05	183	99	5	c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENT5A NTRK2 TEK SVEP1 SLC10A6	5.53e-05	183	99	5	81003ddc24164959dd41bb12fcac72638789b8f2
ToppCell	droplet-Heart-4Chambers-21m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAP2 APLP2 TEK SLC18A2 NOS3	5.68e-05	184	99	5	f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCell	control-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ENPP3 ARHGEF12 SLC18A2 OSBPL1A BCAR3	5.68e-05	184	99	5	fad517d047e8eaeaa5bd4f311d770880568dd13c
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 ARHGEF17 ADARB1 SVEP1 SLC10A6	5.98e-05	186	99	5	ca5e9c6531cb5d199e27509bfab1d62e3937177e
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 ARHGEF17 ADARB1 SVEP1 SLC10A6	5.98e-05	186	99	5	1ed71b229f40a680071b14f5a7a19706e0fd14b1
ToppCell	facs-Heart-RA-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 APLP2 TEK SLC18A2 NOS3	6.29e-05	188	99	5	4ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCell	facs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 APLP2 TEK SLC18A2 NOS3	6.29e-05	188	99	5	e47e66906922d5c69b1aafe28face0787d3fc563
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF23 FBXO17 PTGFR ADARB2 PDZD2	6.29e-05	188	99	5	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	droplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 APLP2 TEK SLC18A2 NOS3	6.44e-05	189	99	5	1137583e21d874c201c20581ba1995e2bfa3de59
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 ARHGEF17 ADARB1 SVEP1 SLC10A6	6.61e-05	190	99	5	00fd993675faf53adf985b9316a18c8a33242029
ToppCell	droplet-Heart-nan-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 APLP2 TEK SLC18A2 NOS3	6.61e-05	190	99	5	7068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 ARHGEF17 ADARB1 SVEP1 SLC10A6	6.61e-05	190	99	5	8cda09d761c6b504a744959d587c183f94f1beeb
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	RBP1 ARHGEF17 ADARB1 SVEP1 SLC10A6	6.77e-05	191	99	5	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	facs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 APLP2 TEK SLC18A2 NOS3	6.94e-05	192	99	5	14a816ef116aa992f86edab411f043cf7d07fe04
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NTRK2 ADARB1 MYOM2 BCAR3 TRIM36	6.94e-05	192	99	5	dee97f650ae6f4d07a142ade402aae1905791a22
ToppCell	facs-Heart-LA-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 APLP2 TEK SLC18A2 NOS3	6.94e-05	192	99	5	847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDKL2 ZSWIM5 NTRK2 APLP2 OSBPL1A	7.11e-05	193	99	5	f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	NWD1 SYNE1 DNAH2 SERPINI2 MAP3K19	7.11e-05	193	99	5	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ENPP3 SYNE1 USP9Y MAP3K4 BRWD1	7.11e-05	193	99	5	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	CDKL2 CECR2 PTGFR DCBLD2 PDZD2	7.11e-05	193	99	5	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDKL2 ZSWIM5 NTRK2 APLP2 OSBPL1A	7.11e-05	193	99	5	4ccf984baebbb13ae916727137ce593fda7514a2
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ACADSB RBP1 ADARB1 SVEP1 SLC10A6	7.29e-05	194	99	5	f15e81ff12525523c62d13105cf264ea72205e2e
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 APLP2 TEK SLC18A2 NOS3	7.29e-05	194	99	5	c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 APLP2 TEK SLC18A2 NOS3	7.47e-05	195	99	5	df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Cajal_Retzius-36\|World / Primary Cells by Cluster	NTRK2 APLP2 ADARB1 DST BCAR3	7.47e-05	195	99	5	bc76a0586cc78f013cb96a2444e63e3c5daa3bc7
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Cajal_Retzius\|World / Primary Cells by Cluster	NTRK2 APLP2 ADARB1 DST BCAR3	7.47e-05	195	99	5	424d8e2bc7f7e68f74219de06dbbb671c8b4c24c
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ACADSB RBP1 ADARB1 SVEP1 SLC10A6	7.47e-05	195	99	5	b072fdc2131173f562e55dd78226eaf2c57d3690
ToppCell	droplet-Heart-nan-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBP1 APLP2 TEK SLC18A2 NOS3	7.65e-05	196	99	5	e386526332138e636aef2542c11316347a45689c
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ENPP3 SYNE1 MAP3K4 PTPRC UHRF2	7.84e-05	197	99	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	10x3'2.3-week_14-16-Myeloid_neutrophil-granulo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CCPG1 TENT5A APLP2 PTPRC SLC18A2	8.03e-05	198	99	5	822df797fffbedf63ff8a8d99ea57511ce55f7cf
ToppCell	Bronchus_Control_(B.)-Endothelial-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	B3GALNT1 ARHGEF12 DDC DST ESPL1	8.03e-05	198	99	5	feac39036b5c0ab97b524cc366286942d136d42f
ToppCell	Bronchus_Control_(B.)-Endothelial-TX-Bronchial_vessel\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	B3GALNT1 ADARB2 DDC DST ESPL1	8.03e-05	198	99	5	dcf334d13e5b0018fee24febccfef91c9e17843b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SYNE1 NTRK2 TEK GABBR1 PDZD2	8.22e-05	199	99	5	333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SYNE1 NTRK2 TEK GABBR1 PDZD2	8.22e-05	199	99	5	e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	SYNE1 ARHGEF12 USP9Y PTPRC MYOM2	8.41e-05	200	99	5	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-BMP_responsible_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	RBP1 PTPRC OSBPL1A GALNT5 MAP3K19	8.41e-05	200	99	5	a4b52466b6426a835655b5fe7487e15aea816e14
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Mesenchymal-Cilia-bearing_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	NWD1 RBP1 GALNT5 MAP3K19 PDZD2	8.41e-05	200	99	5	c6060205cab46628d845edbf17e2c5be7508181c
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	B3GALNT1 CECR2 ZBTB22 GTF2IRD2B	9.22e-05	106	99	4	005ca899efc5ad0c9c17b2697022b594c8cea2c1
Disease	Abnormality of the sense of smell, COVID-19 symptoms measurement, ageusia	UGT2A2 UGT2A1	1.07e-05	2	97	2	EFO_0600019, EFO_1001758, HP_0004408
Disease	Drug habituation	SYNE1 ADARB2 WDR11 BCAR3 DNAH8	3.99e-05	115	97	5	C0013170
Disease	Substance-Related Disorders	SYNE1 ADARB2 WDR11 BCAR3 DNAH8	3.99e-05	115	97	5	C0236969
Disease	Drug abuse	SYNE1 ADARB2 WDR11 BCAR3 DNAH8	3.99e-05	115	97	5	C0013146
Disease	Drug Use Disorders	SYNE1 ADARB2 WDR11 BCAR3 DNAH8	3.99e-05	115	97	5	C0013222
Disease	Drug Dependence	SYNE1 ADARB2 WDR11 BCAR3 DNAH8	3.99e-05	115	97	5	C1510472
Disease	Substance Dependence	SYNE1 ADARB2 WDR11 BCAR3 DNAH8	3.99e-05	115	97	5	C0038580
Disease	Substance Use Disorders	SYNE1 ADARB2 WDR11 BCAR3 DNAH8	3.99e-05	115	97	5	C0038586
Disease	Organic Mental Disorders, Substance-Induced	SYNE1 ADARB2 WDR11 BCAR3 DNAH8	3.99e-05	115	97	5	C0029231
Disease	Prescription Drug Abuse	SYNE1 ADARB2 WDR11 BCAR3 DNAH8	3.99e-05	115	97	5	C4316881
Disease	Substance abuse problem	SYNE1 ADARB2 WDR11 BCAR3 DNAH8	4.16e-05	116	97	5	C0740858
Disease	Nerve Degeneration	APLP2 DDC SLC18A2 KCNJ4	1.65e-04	83	97	4	C0027746
Disease	Parkinson Disease	ADARB2 DDC SLC18A2 KCNJ4	1.81e-04	85	97	4	C0030567
Disease	Uterine leiomyoma	SYNE1 DNAH2 UGT2A1 REV1	2.36e-04	91	97	4	HP_0000131
Disease	colitis (biomarker_via_orthology)	NTRK2 TACR2 NOS3	3.60e-04	42	97	3	DOID:0060180 (biomarker_via_orthology)
Disease	niacinamide measurement	OSBPL1A EXOC2	6.91e-04	12	97	2	EFO_0010511
Disease	Oligospermia	NOS3 BRWD1	6.91e-04	12	97	2	C0028960
Disease	Bipolar Disorder	SYNE1 NTRK2 ADARB1 DDC SLC18A2 DNAH8 NOS3	1.02e-03	477	97	7	C0005586
Disease	Cocaine Dependence	NTRK2 SLC18A2 DNAH8 GABBR1	1.16e-03	139	97	4	C0600427
Disease	Fetal Growth Retardation	RBP1 NOS3	1.96e-03	20	97	2	C0015934
Disease	gastric ulcer (biomarker_via_orthology)	TEK NOS3	2.16e-03	21	97	2	DOID:10808 (biomarker_via_orthology)
Disease	Disease Exacerbation	CDKL2 XPC CPSF1 SYMPK	2.18e-03	165	97	4	C0235874
Disease	portal hypertension (biomarker_via_orthology)	DDC NOS3	2.37e-03	22	97	2	DOID:10762 (biomarker_via_orthology)
Disease	Ovarian Serous Adenocarcinoma	TEK MAP3K4	2.59e-03	23	97	2	C1335177
Disease	Hereditary Diffuse Gastric Cancer	RBP1 CPSF1 DCBLD2 NOS3 SYMPK	2.86e-03	293	97	5	C1708349
Disease	Stomach Neoplasms	RBP1 CPSF1 DCBLD2 NOS3 SYMPK	3.03e-03	297	97	5	C0038356
Disease	Malignant neoplasm of stomach	RBP1 CPSF1 DCBLD2 NOS3 SYMPK	3.16e-03	300	97	5	C0024623

Protein segments in the cluster

Peptide	Gene	Start	Entry
VKCCSWSADGARIMV	APAF1	801	O14727
EICKTEFQMRLLWGS	BCAR3	776	O75815
EIAGQTTSKCIEWMG	ACADSB	376	P45954
AGCKVITSWDQMCIE	CD180	16	Q99467
CSAMWVKKRTDLTGA	DDC	311	P20711
KAVEGMCSVRVVWRG	CECR2	366	Q9BXF3
TVSEKTVWQDLICRM	ARHGEF12	1116	Q9NZN5
TVWQDLICRMAASVK	ARHGEF12	1121	Q9NZN5
KQEVLGSMSWISCRG	NWD1	746	Q149M9
LISGSRDTTCMIWQI	NBEAL1	2456	Q6ZS30
ITMSCTDKIARWNVL	ADARB2	551	Q9NS39
SWMEEVIKLCGRELV	RLN2	26	P04090
KICHMVSDGSWVVRV	INTS4	286	Q96HW7
AVISVRDGKLCLMWR	KCNJ4	191	P48050
RCVACMVDSSLGVWV	ARHGEF17	1861	Q96PE2
WHTVVKEACLTQGMT	APLP2	166	Q06481
VQKEWMRLCTSVTES	PMPCB	381	O75439
DMLSELRDKWDTICG	DST	6786	Q03001
MQELSTRWETVCALS	DST	6896	Q03001
CSSVSTLVAEAARMW	GABBR1	246	Q9UBS5
MVSWSVIAKIQEICE	AQP7P3	16	A6NL99
TLKTIMAFRWVTEFC	B3GALNT1	156	O75752
EWEHVTCMKTVSLRS	CPSF1	1096	Q10570
ETCETTLFALRMATW	PTGFR	281	P43088
TAEWMSASKIVCRVG	EXOC2	51	Q96KP1
SDCLAREEVGRIWKM	PDZD2	321	O15018
GLMVTCSKDRSIAVW	FBXW11	331	Q9UKB1
IWQGMLTIKAEECAS	DNAH8	2666	Q96JB1
KADIWSVACTVVEML	MAP3K2	541	Q9Y2U5
GAAWVLCLLKSVTEM	OR13J1	146	Q8NGT2
MSDRKCVELVTGSWI	OR5J2	136	Q8NH18
DFSIWSILRKCIGME	OSBPL1A	546	Q9BXW6
LLTMSCSDKIARWNV	ADARB1	551	P78563
ALSTWSLKTMCSLRE	IQSEC3	416	Q9UPP2
VCMDLDTRTTSSLWK	NOS3	381	P29474
CSKRQLVDLVMEGVW	FBXO17	156	Q96EF6
KAVDVWAIGCLVTEM	CDKL2	181	Q92772
IWSIGCIFAEMVTRK	CDK3	186	Q00526
MTSGVVLCEGVKWLS	CNOT7	141	Q9UIV1
NLARCWTLTEAEKMS	CCPG1	281	Q9ULG6
LVDSCKSTVVWMLEA	ESPL1	426	Q14674
RCVVAEVMKTRTGSW	CD101	376	Q93033
VKSLGMNDTRETCWK	DNAH17	2901	Q9UFH2
EDTCVESTRIWMCNK	ENPP3	86	O14638
LDQWVFGTVMCKVVS	CCR8	96	P51685
IMCFVDEVWSTLLRS	GALNT5	501	Q7Z7M9
SMTIETVDVGWCKEI	FBXL17	616	Q9UF56
TWSLLGEMSEKLRRC	C3orf62	6	Q6ZUJ4
TMIAAGSCDKIIRVW	BRWD1	241	Q9NSI6
MTSGVVLCDNVKWLS	CNOT8	141	Q9UFF9
STVCEWEIRVKMGER	DCBLD2	96	Q96PD2
MDVVVKSVNWICSRG	GTF2IRD2	671	Q86UP8
MDVVVKSVNWICSRG	GTF2IRD2B	671	Q6EKJ0
MIWSVCASVDEEGRK	DNAH2	2321	Q9P225
TIVMEWDLVCEARTL	SLC22A20P	121	A6NK97
RKSDIWSIGCTVFEM	MAP3K19	1246	Q56UN5
LRTKTTWMVSSCEVR	NEURL4	1001	Q96JN8
TVTMDQGATKCVVAW	TACR2	171	P21452
ALVQREKMCLWSTDA	CDC37L1	116	Q7L3B6
MLGTDRCVVEEWLSE	FAM126B	1	Q8IXS8
RKADVWSLGCTVVEM	MAP3K3	546	Q99759
WTDVETRCSVAVEMR	KIF23	926	Q02241
ADIWSLGCVVIEMVT	MAP3K4	1526	Q9Y6R4
ETLECREMWKGFILT	STAP2	101	Q9UGK3
MSWNEIEVCGTSKII	TRIM36	461	Q9NQ86
VKDMWASLLSAGIRC	SYNE1	3366	Q8NF91
TGIDDRKCMTTVSWD	RBP1	76	P09455
RKCMTTVSWDGDKLQ	RBP1	81	P09455
RALKMGCRSVELDVW	PLCL2	461	Q9UPR0
CMADKAWTISRVVGQ	SPATA31E1	1311	Q6ZUB1
IERGCVKESGSHMWI	SLCO1B7	111	G3V0H7
CSEETTRLAKVVMQW	PLB1	241	Q6P1J6
SGVKEMLRCTTSGKW	SVEP1	536	Q4LDE5
LMGVTKITCLESGEW	SVEP1	1821	Q4LDE5
SCTIGMVLRLWSDTK	SSH1	136	Q8WYL5
VMSDWDTSCLQRTIK	LINC00615	106	Q96LM1
TCSCDIMWIKTLQEA	NTRK2	151	Q16620
MWIQVRTIDGSKTCT	UHRF2	1	Q96PU4
TMLLTRINCADWSDV	TXNDC16	441	Q9P2K2
EMVRWLVTCATEVGV	ZSWIM5	886	Q9P217
ISMWKCELTEFVNTL	REV1	361	Q9UBZ9
LLLSTSMDRDVKCWD	GEMIN5	351	Q8TEQ6
WMIVREETRGECTDL	ZNF607	66	Q96SK3
MFSLGCSVEIRKLWS	SLC10A6	46	Q3KNW5
CAEMISTWVERKTDG	SERPINI2	146	O75830
VWVCSVNTVAGMVEK	TEK	421	Q02763
MGTAITTCEALTEWE	USP9Y	1531	O00507
LWDVEQGVCTHTLMK	TBL1Y	436	Q9BQ87
MKVWETVQRKGTTSC	TFDP3	116	Q5H9I0
LEAVEVKWSVRMTLC	SPRTN	61	Q9H040
VKWSVRMTLCAGICS	SPRTN	66	Q9H040
KSRVISELQEACWDM	SYMPK	146	Q92797
TIRNLDCIGMKWEDT	ZNF442	61	Q9H7R0
EMVRWLVTCATEVGV	ZSWIM6	916	Q9HCJ5
SQWEVMESSKLCGLE	ZNF529	101	Q6P280
DPVWMTVTRKCRVDA	XPC	586	Q01831
SDGRVMIWELKSAVC	WDR11	376	Q9BZH6
ILTQGRCDIDEWMTK	RS1	136	O15537
ETMCSRKWQLGVAFL	SLC18A2	321	Q05940
MVKVCNDSDRWSLIS	TENT5A	191	Q96IP4
WEQKATVIVMVTRCE	PTPRC	741	P08575
TTLCETMGKAEIWLI	UGT2A1	286	P0DTE4
GSVLQMWHIVDKCTE	ZBTB22	131	O15209
TTLCETMGKAEIWLI	UGT2A2	251	P0DTE5
FCEVRDTSLVMLWKA	MYOM2	821	P54296