Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	STAB2 LRP1B SORL1	9.37e-05	16	113	3	GO:0005041
GeneOntologyMolecularFunction	cargo receptor activity	MIA3 STAB2 LRP1B SCARA3 SORL1	1.21e-04	85	113	5	GO:0038024
GeneOntologyMolecularFunction	single base insertion or deletion binding	PMS2 MSH3	1.89e-04	4	113	2	GO:0032138
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	STAB2 LRP1B SORL1	2.18e-04	21	113	3	GO:0030228
GeneOntologyMolecularFunction	DNA insertion or deletion binding	PMS2 MSH3	4.69e-04	6	113	2	GO:0032135
GeneOntologyCellularComponent	Z disc	MYH7 NEBL NEB XIRP2 SCN8A DMD	1.89e-04	151	115	6	GO:0030018
GeneOntologyCellularComponent	contractile actin filament bundle	MYH7 NEBL ROR1 PTPN11 XIRP2	3.14e-04	107	115	5	GO:0097517
GeneOntologyCellularComponent	stress fiber	MYH7 NEBL ROR1 PTPN11 XIRP2	3.14e-04	107	115	5	GO:0001725
GeneOntologyCellularComponent	I band	MYH7 NEBL NEB XIRP2 SCN8A DMD	3.16e-04	166	115	6	GO:0031674
GeneOntologyCellularComponent	actin cytoskeleton	FILIP1 MYH7 NEBL ROR1 GABARAP NEB PTPN11 XIRP2 TAF5 HCK EPB41L2	3.38e-04	576	115	11	GO:0015629
GeneOntologyCellularComponent	actomyosin	MYH7 NEBL ROR1 PTPN11 XIRP2	4.74e-04	117	115	5	GO:0042641
GeneOntologyCellularComponent	actin filament bundle	MYH7 NEBL ROR1 PTPN11 XIRP2	4.93e-04	118	115	5	GO:0032432
Domain	-	ARHGAP10 SHC4 PREX2 EXOC8 PTPN3 TIAM1 CADPS VAV3 FGD5 MCF2L EPB41L2 PHLDB2 AGAP3	7.04e-07	391	113	13	2.30.29.30
Domain	PH	ARHGAP10 PREX2 EXOC8 TIAM1 CADPS VAV3 FGD5 MCF2L PHLDB2 AGAP3	1.30e-06	229	113	10	PF00169
Domain	PH_dom-like	ARHGAP10 SHC4 PREX2 EXOC8 PTPN3 TIAM1 CADPS VAV3 FGD5 MCF2L EPB41L2 PHLDB2 AGAP3	1.83e-06	426	113	13	IPR011993
Domain	PH	ARHGAP10 PREX2 EXOC8 TIAM1 CADPS VAV3 FGD5 MCF2L PHLDB2 AGAP3	7.32e-06	278	113	10	SM00233
Domain	PH_DOMAIN	ARHGAP10 PREX2 EXOC8 TIAM1 CADPS VAV3 FGD5 MCF2L PHLDB2 AGAP3	7.56e-06	279	113	10	PS50003
Domain	PH_domain	ARHGAP10 PREX2 EXOC8 TIAM1 CADPS VAV3 FGD5 MCF2L PHLDB2 AGAP3	7.80e-06	280	113	10	IPR001849
Domain	RhoGEF	PREX2 TIAM1 VAV3 FGD5 MCF2L	5.71e-05	68	113	5	SM00325
Domain	RhoGEF	PREX2 TIAM1 VAV3 FGD5 MCF2L	6.56e-05	70	113	5	PF00621
Domain	DH_2	PREX2 TIAM1 VAV3 FGD5 MCF2L	6.56e-05	70	113	5	PS50010
Domain	-	PREX2 TIAM1 VAV3 FGD5 MCF2L	7.03e-05	71	113	5	1.20.900.10
Domain	DH-domain	PREX2 TIAM1 VAV3 FGD5 MCF2L	7.03e-05	71	113	5	IPR000219
Domain	GDS_CDC24_CS	PREX2 TIAM1 VAV3 MCF2L	8.87e-05	39	113	4	IPR001331
Domain	Nebulin	NEBL NEB	2.16e-04	4	113	2	PF00880
Domain	NEBULIN	NEBL NEB	2.16e-04	4	113	2	PS51216
Domain	NEBU	NEBL NEB	2.16e-04	4	113	2	SM00227
Domain	Nebulin	NEBL NEB	2.16e-04	4	113	2	IPR013998
Domain	Nebulin_repeat	NEBL NEB	2.16e-04	4	113	2	IPR000900
Domain	SH3	MIA3 NEBL ARHGAP10 NEB VAV3 MCF2L HCK	3.44e-04	216	113	7	SM00326
Domain	SH3	MIA3 NEBL ARHGAP10 NEB VAV3 MCF2L HCK	3.44e-04	216	113	7	PS50002
Domain	SH3_domain	MIA3 NEBL ARHGAP10 NEB VAV3 MCF2L HCK	3.84e-04	220	113	7	IPR001452
Domain	DH_1	PREX2 TIAM1 VAV3 MCF2L	5.75e-04	63	113	4	PS00741
Domain	BBOX	TRIM49 TRIM49C TRIM49D1 TRIM49B	8.11e-04	69	113	4	SM00336
Domain	Butyrophylin	TRIM49 TRIM49C TRIM49D1 TRIM49B	8.57e-04	70	113	4	IPR003879
Domain	-	TRIM49 TRIM49C TRIM49D1 TRIM49B	9.04e-04	71	113	4	4.10.45.10
Domain	zf-B_box	TRIM49 TRIM49C TRIM49D1 TRIM49B	9.52e-04	72	113	4	PF00643
Domain	PTPc	PTPN3 PTPN11 PTPRB	1.33e-03	36	113	3	SM00194
Domain	ZF_BBOX	TRIM49 TRIM49C TRIM49D1 TRIM49B	1.41e-03	80	113	4	PS50119
Domain	Znf_B-box	TRIM49 TRIM49C TRIM49D1 TRIM49B	1.48e-03	81	113	4	IPR000315
Domain	TYR_PHOSPHATASE_PTP	PTPN3 PTPN11 PTPRB	1.68e-03	39	113	3	PS50055
Domain	-	ELP1 LRP1B SORL1	1.68e-03	39	113	3	2.120.10.30
Domain	LDLR_class-A_CS	LRP1B MALRD1 SORL1	1.81e-03	40	113	3	IPR023415
Domain	SPRY	TRIM49 TRIM49C TRIM49D1 TRIM49B	1.92e-03	87	113	4	SM00449
Domain	PTPase_domain	PTPN3 PTPN11 PTPRB	1.94e-03	41	113	3	IPR000242
Domain	Y_phosphatase	PTPN3 PTPN11 PTPRB	1.94e-03	41	113	3	PF00102
Domain	Ldl_recept_a	LRP1B MALRD1 SORL1	2.54e-03	45	113	3	PF00057
Domain	SPRY	TRIM49 TRIM49C TRIM49D1 TRIM49B	2.55e-03	94	113	4	PF00622
Domain	SPRY_dom	TRIM49 TRIM49C TRIM49D1 TRIM49B	2.55e-03	94	113	4	IPR003877
Domain	B30.2/SPRY	TRIM49 TRIM49C TRIM49D1 TRIM49B	2.65e-03	95	113	4	IPR001870
Domain	B302_SPRY	TRIM49 TRIM49C TRIM49D1 TRIM49B	2.65e-03	95	113	4	PS50188
Domain	6-blade_b-propeller_TolB-like	ELP1 LRP1B SORL1	2.71e-03	46	113	3	IPR011042
Domain	-	LRP1B MALRD1 SORL1	2.71e-03	46	113	3	4.10.400.10
Domain	PP2Ac	PPEF2 PPP6C	2.71e-03	13	113	2	SM00156
Domain	Ser/Thr-sp_prot-phosphatase	PPEF2 PPP6C	2.71e-03	13	113	2	IPR006186
Domain	SER_THR_PHOSPHATASE	PPEF2 PPP6C	2.71e-03	13	113	2	PS00125
Domain	LDLRA_1	LRP1B MALRD1 SORL1	3.06e-03	48	113	3	PS01209
Domain	Ldl_recept_b	LRP1B SORL1	3.15e-03	14	113	2	PF00058
Domain	LDLRB	LRP1B SORL1	3.15e-03	14	113	2	PS51120
Domain	SH3_1	NEBL ARHGAP10 NEB VAV3 HCK	3.22e-03	164	113	5	PF00018
Domain	LDrepeatLR_classA_rpt	LRP1B MALRD1 SORL1	3.24e-03	49	113	3	IPR002172
Domain	LDLa	LRP1B MALRD1 SORL1	3.24e-03	49	113	3	SM00192
Domain	LDLRA_2	LRP1B MALRD1 SORL1	3.24e-03	49	113	3	PS50068
Domain	SH2	SHC4 PTPN11 VAV3 HCK	3.31e-03	101	113	4	PF00017
Domain	LY	LRP1B SORL1	3.62e-03	15	113	2	SM00135
Domain	LDLR_classB_rpt	LRP1B SORL1	3.62e-03	15	113	2	IPR000033
Domain	SH2	SHC4 PTPN11 VAV3 HCK	4.48e-03	110	113	4	SM00252
Domain	SH2	SHC4 PTPN11 VAV3 HCK	4.63e-03	111	113	4	PS50001
Domain	SH2	SHC4 PTPN11 VAV3 HCK	4.78e-03	112	113	4	IPR000980
Domain	-	SHC4 PTPN11 VAV3 HCK	4.78e-03	112	113	4	3.30.505.10
Domain	PTPc_motif	PTPN3 PTPN11 PTPRB	5.48e-03	59	113	3	SM00404
Domain	Tyr_Pase_cat	PTPN3 PTPN11 PTPRB	5.48e-03	59	113	3	IPR003595
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PMS2 MIA3 ARHGAP10 ELP1 GABARAP CEP192 PPEF2 CDCA2 PTPN3 RIF1 LONP1 PTPN11 PTPRB TTC7B NUP155 PPP6C TIAM1 PRPF4 DMD	2.01e-09	1049	116	19	27880917
Pubmed	Identification of a genomic reservoir for new TRIM genes in primate genomes.	TRIM49 TRIM49C TRIM49D1 TRIM49B TRIM51G	4.24e-09	19	116	5	22144910
Pubmed	Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.	NEBL NEB XIRP2	1.44e-07	4	116	3	23985323
Pubmed	Novel associations for hypothyroidism include known autoimmune risk loci.	PTPN11 SACS TEX47 MTF1 VAV3	3.70e-07	44	116	5	22493691
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	ARHGAP10 PREX2 RIF1 LONP1 PPP6C TIAM1 SNRNP40 VAV3 FGD5 DMD MCF2L EPB41L2 SORL1 AGAP3	2.36e-06	916	116	14	32203420
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	AARS1 ELP1 APOB MSH3 CDCA2 RIF1 LONP1 PTPN11 NUP155 PRPF4 ASNS SNRNP40 MTR SGO2 PRMT1 FGD5 EPB41L2	5.18e-06	1425	116	17	30948266
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FAM86B1 AARS1 PMS2 MSH3 LRP1B FBH1 TTC7B TIAM1 SACS CADPS USP32 KIF5A WDR13 CTSL GEN1 AGAP3	5.92e-06	1285	116	16	35914814
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	AARS1 MSH3 RIF1 LONP1 PTPN11 NUP155 PRPF4 NAE1 KAT8 ASNS SNRNP40 SMARCA2 PRMT1 MED26	7.53e-06	1014	116	14	32416067
Pubmed	Mutation of ARHGAP9 in patients with coronary spastic angina.	ARHGAP10 TIAM1 VAV3 MCF2L	7.94e-06	38	116	4	19911011
Pubmed	cDNA cloning of new protein tyrosine phosphatases in the human colon.	PTPN3 PTPN11	1.10e-05	2	116	2	1626183
Pubmed	Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.	NEBL NEB	1.10e-05	2	116	2	19851499
Pubmed	Variants in NEB and RIF1 genes on chr2q23 are associated with skeletal muscle index in Koreans: genome-wide association study.	NEB RIF1	1.10e-05	2	116	2	33674626
Pubmed	Mapping of the gene coding for the muscle protein nebulin (Neb) to the proximal region of mouse chromosome 2.	NEB C5	1.10e-05	2	116	2	1683831
Pubmed	Exome sequencing: an efficient diagnostic tool for complex neurodegenerative disorders.	APOB SACS	1.10e-05	2	116	2	23043354
Pubmed	Cep295 is a conserved scaffold protein required for generation of a bona fide mother centriole.	CEP192 CEP295	1.10e-05	2	116	2	27562453
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	AARS1 ELP1 MSH3 CDCA2 TGM1 RIF1 LONP1 NUP155 PPP6C ASNS SNRNP40 SMARCA2 PRMT1 WDR13 EPB41L2 PHLDB2	1.12e-05	1353	116	16	29467282
Pubmed	Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.	TRIM49 TRIM49C TRIM49B	1.60e-05	15	116	3	19703589
Pubmed	Interspecific backcross mice show sex-specific differences in allelic inheritance.	NEB C5 HCK	1.60e-05	15	116	3	1916246
Pubmed	Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins.	CEP192 CDCA2 RIF1	1.96e-05	16	116	3	29764992
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	FILIP1 RIF1 NUP155 TIAM1 PRPF4 SNRNP40 SMARCA2	2.18e-05	250	116	7	33536335
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	AARS1 ARHGAP10 ELP1 EXOC8 PTPN3 PTPN11 NUP155 ASNS PRMT1 OS9 KIF5A DMD SORL1	2.32e-05	974	116	13	28675297
Pubmed	TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum.	MIA3 APOB	3.30e-05	3	116	2	27138255
Pubmed	SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women.	APOB PTPN11	3.30e-05	3	116	2	17214991
Pubmed	Recently reported familial hypercholesterolemia-related mutations from cases in the Middle East and North Africa region.	APOB SORL1	3.30e-05	3	116	2	30694837
Pubmed	Semenogelin I and semenogelin II, the major gel-forming proteins in human semen, are substrates for transglutaminase.	SEMG2 TGM1	3.30e-05	3	116	2	9523691
Pubmed	Multiple mutations and frameshifts are the hallmark of defective hPMS2 in pZ189-transfected human tumor cells.	PMS2 MSH3	3.30e-05	3	116	2	10871409
Pubmed	Cloning and characterization of human CADPS and CADPS2, new members of the Ca2+-dependent activator for secretion protein family.	CADPS DMD	3.30e-05	3	116	2	12659812
Pubmed	Alleviating transcriptional inhibition of the norepinephrine slc6a2 transporter gene in depolarized neurons.	SLC6A2 SMARCA2	3.30e-05	3	116	2	20107077
Pubmed	A human MAP kinase interactome.	NEB PTPN3 RIF1 OS9 VAV3 KIF5A DMD HCK EPB41L2	3.84e-05	486	116	9	20936779
Pubmed	TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.	TRIM49 GABARAP EXOC8	3.95e-05	20	116	3	25127057
Pubmed	ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.	AARS1 IDH1 PTPN11 CADPS PRMT1 AGAP3	6.22e-05	202	116	6	33601422
Pubmed	Beta-dystrobrevin interacts directly with kinesin heavy chain in brain.	KIF5A DMD	6.59e-05	4	116	2	14600269
Pubmed	Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes.	KMT2B PRMT1	6.59e-05	4	116	2	26267306
Pubmed	Isolation and characterization of two evolutionarily conserved murine kinases (Nek6 and nek7) related to the fungal mitotic regulator, NIMA.	NEB C5	6.59e-05	4	116	2	10964517
Pubmed	The mismatch repair system protects against intergenerational GAA repeat instability in a Friedreich ataxia mouse model.	PMS2 MSH3	6.59e-05	4	116	2	22289650
Pubmed	Rho GEFs and cancer: linking gene expression and metastatic dissemination.	PREX2 VAV3	6.59e-05	4	116	2	23033535
Pubmed	Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice.	MYH7 DMD	6.59e-05	4	116	2	25139234
Pubmed	Structural and Functional Analyses of the FAM46C/Plk4 Complex.	CEP192 TENT5D	6.59e-05	4	116	2	32433990
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	COL6A2 AARS1 MIA3 ELP1 EXOC8 PHKA2 NUP155 AACS MTR SORL1	6.70e-05	650	116	10	38777146
Pubmed	Human transcription factor protein interaction networks.	KMT2B ETV3 CEP192 ZNF850 INO80D CDCA2 RIF1 LONP1 PPP6C KAT8 SMARCA2 MTR PRMT1 TAF5 SORL1	8.37e-05	1429	116	15	35140242
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ARHGAP10 INO80D ARSB PRPF4 CADPS SMARCA2 MTR CEP295 TAF5 WDR13 PHLDB2 SORL1 AGAP3	9.25e-05	1116	116	13	31753913
Pubmed	Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.	SHC4 PTPN11 VAV3 HCK	1.07e-04	73	116	4	24728074
Pubmed	Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.	NEB C5	1.10e-04	5	116	2	1679748
Pubmed	His-1 and His-2: identification and chromosomal mapping of two commonly rearranged sites of viral integration in a myeloid leukemia.	NEB C5	1.10e-04	5	116	2	1682866
Pubmed	The interaction of DNA mismatch repair proteins with human exonuclease I.	PMS2 MSH3	1.10e-04	5	116	2	11427529
Pubmed	Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6.	PMS2 MSH3	1.10e-04	5	116	2	16728433
Pubmed	PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer.	PRMT1 C5	1.10e-04	5	116	2	38691454
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	ELP1 MSH3 EXOC8 LONP1 NUP155 PPP6C ASNS SNRNP40 EPB41L2	1.13e-04	560	116	9	35241646
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	MIA3 ELP1 CEP192 LONP1 PPP6C CEP295 PHLDB2 AGAP3	1.30e-04	446	116	8	24255178
Pubmed	Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.	SHC4 PTPN11 VAV3 HCK	1.32e-04	77	116	4	22973453
Pubmed	Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.	SACS PLCXD3 SORL1	1.52e-04	31	116	3	27798109
Pubmed	Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression.	APOB ARSB	1.64e-04	6	116	2	1352323
Pubmed	P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.	PREX2 VAV3	1.64e-04	6	116	2	25538043
Pubmed	Muscle dysfunction caused by loss of Magel2 in a mouse model of Prader-Willi and Schaaf-Yang syndromes.	MYH7 DMD	1.64e-04	6	116	2	27436578
Pubmed	Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2.	PTPN11 HCK	1.64e-04	6	116	2	16684964
Pubmed	Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells.	C5 MX1	1.64e-04	6	116	2	36720219
Pubmed	hMutSalpha forms an ATP-dependent complex with hMutLalpha and hMutLbeta on DNA.	PMS2 MSH3	1.64e-04	6	116	2	11809883
Pubmed	DNA mismatch repair and cancer.	PMS2 MSH3	1.64e-04	6	116	2	11223406
Pubmed	A protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptor.	PTPN11 PRMT1	1.64e-04	6	116	2	9029147
Pubmed	Developmental regulation of biglycan expression in muscle and tendon.	COL6A2 DMD	1.64e-04	6	116	2	16810681
Pubmed	FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability.	ZXDC PPP6C FBXO42	1.67e-04	32	116	3	35813202
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	AARS1 IDH1 EXOC8 LONP1 PTPN11 NUP155 PRPF4 NAE1 ASNS PRMT1 EPB41L2	1.77e-04	878	116	11	37223481
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	AARS1 IDH1 LONP1 PTPN11 NUP155 ASNS SNRNP40 PRMT1 EPB41L2	2.06e-04	607	116	9	39147351
Pubmed	An investigation into the human serum "interactome".	TIAM1 SACS SGO2 DMD CTSL	2.18e-04	162	116	5	15174051
Pubmed	Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors.	SHC4 PTPN11	2.29e-04	7	116	2	28213521
Pubmed	P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses.	PREX2 VAV3	2.29e-04	7	116	2	21178006
Pubmed	Direct cDNA selection with DNA microdissected from mouse chromosome 16: isolation of novel clones and construction of a partial transcription map of the C3-C4 region.	TIAM1 MX1	2.29e-04	7	116	2	8858343
Pubmed	Global/temporal gene expression in diaphragm and hindlimb muscles of dystrophin-deficient (mdx) mice.	NEB DMD	2.29e-04	7	116	2	12176734
Pubmed	Common germline variation in mismatch repair genes and survival after a diagnosis of colorectal cancer.	PMS2 MSH3	2.29e-04	7	116	2	19115210
Pubmed	Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients.	PMS2 MSH3	2.29e-04	7	116	2	18723338
Pubmed	Common variants in mismatch repair genes and risk of invasive ovarian cancer.	PMS2 MSH3	2.29e-04	7	116	2	16774946
Pubmed	Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code.	SMARCA2 MED26	2.29e-04	7	116	2	20111005
Pubmed	Common variants in mismatch repair genes and risk of colorectal cancer.	PMS2 MSH3	2.29e-04	7	116	2	18364438
Pubmed	Strain distribution pattern for SSLP markers in the SWXJ recombinant inbred strain set: chromosomes 1 to 6.	IDH1 C5	2.29e-04	7	116	2	8747926
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	RIF1 KAT8 PRMT1 KIF5A MED26	2.51e-04	167	116	5	20362541
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	MYH7 ELP1 GABARAP NEB PTPN11 XIRP2 OS9 ZNF426	2.71e-04	497	116	8	23414517
Pubmed	Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.	TIAM1 VAV3 MCF2L	2.80e-04	38	116	3	11756498
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	ELP1 RIF1 LONP1 NUP155 PRPF4 ASNS SNRNP40 EPB41L2 AGAP3	2.97e-04	638	116	9	33239621
Pubmed	HIV-1 Tat C phosphorylates VE-cadherin complex and increases human brain microvascular endothelial cell permeability.	PTPN11 PTPRB	3.05e-04	8	116	2	24965120
Pubmed	Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I.	PMS2 MSH3	3.05e-04	8	116	2	16260499
Pubmed	Cloning, characterization, and genomic structure of the mouse Ikbkap gene.	ELP1 PTPN3	3.05e-04	8	116	2	11747609
Pubmed	Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.	NEBL NEB	3.05e-04	8	116	2	11309420
Pubmed	FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.	PMS2 MSH3	3.05e-04	8	116	2	34469738
Pubmed	P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.	PREX2 VAV3	3.05e-04	8	116	2	24659802
Pubmed	A genetic map of mouse chromosome 1 near the Lsh-Ity-Bcg disease resistance locus.	IDH1 NEB	3.05e-04	8	116	2	1970800
Pubmed	Antitumor efficacy of 90Y-NM600 targeted radionuclide therapy and PD-1 blockade is limited by regulatory T cells in murine prostate tumors.	C5 MX1	3.05e-04	8	116	2	36002185
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	AARS1 KMT2B ZNF652 INO80D PRPF4 NAE1 KAT8 ASNS SNRNP40 SMARCA2 PRMT1 PRPF39	3.25e-04	1103	116	12	34189442
Pubmed	FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.	CEP192 NEB SACS	3.77e-04	42	116	3	29348145
Pubmed	Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor.	PTPN3 PTPRB	3.91e-04	9	116	2	12907755
Pubmed	Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.	KIF5A C5	3.91e-04	9	116	2	19674979
Pubmed	The Src homology and collagen A (ShcA) adaptor protein is required for the spatial organization of the costamere/Z-disk network during heart development.	NEBL DMD	3.91e-04	9	116	2	25488665
Pubmed	Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis.	NEB PTPRB	3.91e-04	9	116	2	20018779
Pubmed	Atf4 regulates obesity, glucose homeostasis, and energy expenditure.	AARS1 ASNS	3.91e-04	9	116	2	19690063
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	MSH3 RIF1 TTC7B ASNS SMARCA2 TAF5 MED26 EPB41L2	4.32e-04	533	116	8	30554943
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	MYH7 IDH1 RIF1 PPP6C NAE1 DMD PHLDB2 AGAP3	4.59e-04	538	116	8	28524877
Pubmed	Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation.	TGM1 SMARCA2	4.88e-04	10	116	2	16192310
Pubmed	RNF219/α-Catenin/LGALS3 Axis Promotes Hepatocellular Carcinoma Bone Metastasis and Associated Skeletal Complications.	KMT2B PRMT1	4.88e-04	10	116	2	33643786
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	ROR1 MUC16 APOB LONP1 PTPN11 PTPRB EPB41L2	5.37e-04	420	116	7	28065597
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	PMS2 APOB MSH3 TGM1 BPI MTR MX1	5.45e-04	421	116	7	19692168
Pubmed	The protein interaction landscape of the human CMGC kinase group.	SEMG2 GABARAP NEB PRPF4 KAT8 SNRNP40 MTR PRMT1 SORL1	5.51e-04	695	116	9	23602568
Interaction	DEFB123 interactions	TMEM67 COL6A2 LRP1B SORL1	1.62e-06	16	113	4	int:DEFB123
Cytoband	7q32.3	PLXNA4 SMO	8.40e-04	17	116	2	7q32.3
Cytoband	9q31	ELP1 PTPN3	8.40e-04	17	116	2	9q31
Cytoband	16q22	AARS1 NAE1	8.40e-04	17	116	2	16q22
Cytoband	5p13.1	NUP155 PLCXD3	9.43e-04	18	116	2	5p13.1
Cytoband	9q21.33	CTSL3P CTSL	9.43e-04	18	116	2	9q21.33
Cytoband	2q33.3	IDH1 INO80D	2.63e-03	30	116	2	2q33.3
Cytoband	11q14.3	TRIM49C TRIM49D1	2.99e-03	32	116	2	11q14.3
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PREX2 TIAM1 VAV3 FGD5 MCF2L	1.54e-05	66	86	5	722
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	TIAM1 CADPS VAV3 FGD5 MCF2L PHLDB2 AGAP3	5.65e-05	206	86	7	682
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM49 TRIM49C TRIM49D1 TRIM49B TRIM51G	8.96e-05	95	86	5	59
GeneFamily	SH2 domain containing	SHC4 PTPN11 VAV3 HCK	1.37e-03	101	86	4	741
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPEF2 PPP6C	1.69e-03	13	86	2	693
GeneFamily	Protein tyrosine phosphatases, non-receptor type	PTPN3 PTPN11	3.26e-03	18	86	2	812
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	ARHGAP10 HTRA4 ARSB TTC7B TIAM1 MTF1 VAV3 CTSL HCK	2.00e-09	192	116	9	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FILIP1 MYH7 NEBL ROR1 XIRP2 CADPS PLCXD3 DMD	3.05e-08	185	116	8	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FILIP1 MYH7 NEBL ROR1 XIRP2 PLCXD3 DMD	3.20e-07	170	116	7	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FILIP1 MYH7 NEBL ROR1 XIRP2 PLCXD3 DMD	4.05e-07	176	116	7	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FILIP1 MYH7 NEBL ROR1 XIRP2 PLCXD3 DMD	4.89e-07	181	116	7	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 APOB NEB LRP1B XIRP2 KIF5A DMD	5.47e-07	184	116	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 APOB NEB LRP1B XIRP2 KIF5A DMD	5.47e-07	184	116	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 APOB NEB LRP1B XIRP2 KIF5A DMD	5.47e-07	184	116	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	FILIP1 MYH7 NEBL ROR1 XIRP2 PLCXD3 DMD	5.47e-07	184	116	7	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FILIP1 MYH7 ROR1 XIRP2 CADPS PLCXD3 DMD	5.47e-07	184	116	7	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	FILIP1 MYH7 NEBL ROR1 XIRP2 PLCXD3 DMD	5.67e-07	185	116	7	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	FILIP1 MYH7 NEBL ROR1 XIRP2 PLCXD3 DMD	6.54e-07	189	116	7	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	FILIP1 MYH7 NEBL ROR1 XIRP2 DMD PHLDB2	6.54e-07	189	116	7	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	FILIP1 MYH7 NEBL ROR1 XIRP2 DMD PHLDB2	6.78e-07	190	116	7	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	FILIP1 MYH7 NEBL ROR1 XIRP2 PLCXD3 DMD	7.53e-07	193	116	7	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	FILIP1 MYH7 NEBL ROR1 CADPS PLCXD3 DMD	8.07e-07	195	116	7	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	FILIP1 MYH7 NEBL ROR1 XIRP2 PLCXD3 DMD	8.07e-07	195	116	7	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HTRA4 FAM20C TTC7B TIAM1 VAV3 CTSL HCK	8.94e-07	198	116	7	6a4161680b46b2c12353a693c403b5a4bb3da03f
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	MYH7 NEBL IDH1 XIRP2 VAV3 HCK	5.60e-06	170	116	6	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL PREX2 NMNAT3 FSIP2 VAV3 SCARA3	5.60e-06	170	116	6	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D175\|Adult / Lineage, Cell type, age group and donor	LRP1B PREX2 PTPRB PLXNA4 PLCXD3 FGD5	6.62e-06	175	116	6	0a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 PREX2 PTPRB SACS FGD5 MCF2L	8.02e-06	181	116	6	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	FILIP1 MYH7 NEBL ROR1 XIRP2 DMD	8.28e-06	182	116	6	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	droplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FILIP1 PREX2 PTPRB SACS FGD5 MCF2L	8.28e-06	182	116	6	81279877b920b5a1bc991a07d3031d6458700fe3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ARHGAP10 PLCXD3 DMD EPB41L2	8.28e-06	182	116	6	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ARHGAP10 PLCXD3 DMD EPB41L2	8.28e-06	182	116	6	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	EXOC8 FAM20C ARSB VAV3 CTSL HCK	9.09e-06	185	116	6	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FILIP1 PTPRB NUP155 VAV3 TAF5 MCF2L	9.37e-06	186	116	6	39e475a3c167b33daa63b0c1bfa32451c5f46635
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FILIP1 PTPRB NUP155 VAV3 TAF5 MCF2L	9.37e-06	186	116	6	02418c50fdcca549bf73dedf6199ab4a27862a9b
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Tumor_ECs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	SHC4 PTPRB TTC23 PLCXD3 MCF2L SCARA3	9.66e-06	187	116	6	2713f526f86911fbbf6c7a3e69230f2e6bde31c3
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	FILIP1 NEBL ROR1 NEB CADPS DMD	9.96e-06	188	116	6	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	Control-Endothelial_cells\|Control / group, cell type (main and fine annotations)	PREX2 PTPRB PLCXD3 FGD5 MCF2L EPB41L2	9.96e-06	188	116	6	3953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	FILIP1 MYH7 NEBL ROR1 PLCXD3 DMD	1.06e-05	190	116	6	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ARHGAP10 ROR1 CADPS DMD	1.06e-05	190	116	6	562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ARHGAP10 ROR1 CADPS DMD	1.06e-05	190	116	6	f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	FILIP1 MYH7 NEBL ROR1 PLCXD3 DMD	1.06e-05	190	116	6	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	FILIP1 MYH7 NEBL ROR1 PLCXD3 DMD	1.09e-05	191	116	6	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ROR1 PLCXD3 DMD EPB41L2	1.09e-05	191	116	6	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ROR1 PLCXD3 DMD EPB41L2	1.09e-05	191	116	6	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ARHGAP10 PLCXD3 DMD EPB41L2	1.12e-05	192	116	6	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ARHGAP10 PLCXD3 DMD EPB41L2	1.12e-05	192	116	6	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 ARHGAP10 PREX2 PLCXD3 DMD EPB41L2	1.16e-05	193	116	6	c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 ARHGAP10 PREX2 PLCXD3 DMD EPB41L2	1.16e-05	193	116	6	5b602b1702283184bd3943c2a6f2290b7c37e407
ToppCell	Adult-Endothelial\|Adult / Lineage, Cell type, age group and donor	PREX2 PTPRB PLCXD3 FGD5 MCF2L EPB41L2	1.19e-05	194	116	6	963b3fbee0575af8379baa397ace65949eaf34f7
ToppCell	background-Endothelial_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	FILIP1 STAB2 INO80D PREX2 PTPRB CTSL	1.23e-05	195	116	6	c7d60dabfc7cb310e002cab10003dadfcc34fe33
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NEBL ARHGAP10 PLXNA4 VAV3 EPB41L2 SORL1	1.23e-05	195	116	6	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ARHGAP10 CADPS DMD EPB41L2	1.26e-05	196	116	6	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	FILIP1 STAB2 PREX2 PTPRB FGD5 CTSL	1.26e-05	196	116	6	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	nucseq-Endothelial-Endothelial_Vascular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PREX2 PTPRB PLCXD3 FGD5 MCF2L EPB41L2	1.26e-05	196	116	6	686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 ARHGAP10 PREX2 PLCXD3 DMD EPB41L2	1.26e-05	196	116	6	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ARHGAP10 CADPS DMD EPB41L2	1.26e-05	196	116	6	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 ARHGAP10 PREX2 PLCXD3 DMD EPB41L2	1.26e-05	196	116	6	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	Endothelial\|World / Lineage, Cell type, age group and donor	STAB2 PREX2 PTPRB FGD5 MCF2L EPB41L2	1.26e-05	196	116	6	96c6d78482a130ce4e29f6629972a06d10d7530e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 ARHGAP10 PREX2 PLCXD3 DMD EPB41L2	1.30e-05	197	116	6	09946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ARHGAP10 PREX2 DMD EPB41L2	1.30e-05	197	116	6	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ARHGAP10 PREX2 DMD EPB41L2	1.30e-05	197	116	6	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 ARHGAP10 PREX2 DMD EPB41L2	1.30e-05	197	116	6	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PREX2 PTPRB OPALIN PLXNA4 PLCXD3 FGD5	1.38e-05	199	116	6	3a4deea6e11a0555d27497b7c9983350797aac69
ToppCell	Bronchial-NucSeq-Endothelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PREX2 PTPRB PLCXD3 FGD5 MCF2L EPB41L2	1.38e-05	199	116	6	36a230b80096455df26c2e2c8c05fd6b231508c5
ToppCell	LV-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	MYH7 NEBL XIRP2 PLCXD3 DMD	2.31e-05	130	116	5	a3e12984fb61311e49cc76c59f74f4dffc48faa1
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PREX2 PTPRB SGO2 FGD5 MCF2L	5.53e-05	156	116	5	ff39712c7a2dc1b85c598d5105789aa291dea726
ToppCell	droplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP192 SCN8A SGO2 CEP295 GEN1	7.21e-05	165	116	5	96f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	ZXDC PMS2 MIA3 INO80D MTR	7.42e-05	166	116	5	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	droplet-Marrow-BM-1m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C2orf69 PPEF2 PREX2 PHKA2 MTR	7.85e-05	168	116	5	2e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCell	Control-Mast_cells\|Control / group, cell type (main and fine annotations)	LRP1B TTC7B CADPS VAV3 BEGAIN	8.07e-05	169	116	5	fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL6A2 NEBL PREX2 PTPRB PLCXD3	8.30e-05	170	116	5	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	Control-Mast_cells-Mast_cells\|Control / group, cell type (main and fine annotations)	LRP1B TTC7B CADPS VAV3 BEGAIN	8.30e-05	170	116	5	c80f6d29096c372da95a8407f402349ff1bb7018
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel\|Adult / Lineage, Cell type, age group and donor	LRP1B PREX2 PTPRB CADPS MCF2L	8.77e-05	172	116	5	ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C2orf69 COL6A2 CDCA2 PLCXD3 SCARA3	9.26e-05	174	116	5	1d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	AARS1 SHC4 MUC16 CDCA2 FBH1	9.51e-05	175	116	5	3b5346fba617292de71963b6175e85a4f182fe30
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	AARS1 SHC4 MUC16 CDCA2 FBH1	9.77e-05	176	116	5	dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP10 SMARCA2 PLCXD3 VAV3 PHLDB2	1.00e-04	177	116	5	f902600c639087664316b3cf30cab243bc3d1c5c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5-6_RORB_LINC00320\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LRP1B NMNAT3 VAV3 SCARA3 PHLDB2	1.00e-04	177	116	5	01df8ab3285fa66b4805c555cfbfc4b3b16db919
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 ARHGAP10 PLCXD3 DMD EPB41L2	1.00e-04	177	116	5	b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 ARHGAP10 PLCXD3 DMD EPB41L2	1.03e-04	178	116	5	d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 PLCXD3 DMD EPB41L2	1.03e-04	178	116	5	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM67 COL6A2 PREX2 SMO DMD	1.06e-04	179	116	5	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	LRP1B PLCXD3 VAV3 FGD5 EPB41L2	1.09e-04	180	116	5	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 PREX2 PTPRB VAV3 PHLDB2	1.11e-04	181	116	5	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NEBL TIAM1 SGO2 EPB41L2 AGAP3	1.11e-04	181	116	5	9275531e896e118cee043ed94fd31a0070d9581c
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROR1 CDCA2 ARSB SACS SGO2	1.14e-04	182	116	5	0370b395ceb9d4d66f80cf60dd8c28ac60af5c7b
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	PREX2 PTPRB PLCXD3 FGD5 MCF2L	1.14e-04	182	116	5	d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCell	COVID-19-Heart-CM_4\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FILIP1 XIRP2 CADPS PLCXD3 DMD	1.17e-04	183	116	5	2902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ROR1 ARSB PLXNA4 DMD SCARA3	1.17e-04	183	116	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	IPF-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	COL6A2 ROR1 MUC16 TGM1 PHLDB2	1.17e-04	183	116	5	7df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SGSM1 PREX2 PTPRB FGD5 MCF2L	1.17e-04	183	116	5	c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	STAB2 PTPN3 PTPRB VAV3 FGD5	1.17e-04	183	116	5	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PREX2 PLXNA4 SMO DMD SCARA3	1.17e-04	183	116	5	351d575339038bd4a66f408da518c567444208e8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FILIP1 COL6A2 PLCXD3 DMD EPB41L2	1.20e-04	184	116	5	c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCell	COPD-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	COL6A2 ROR1 MUC16 TGM1 PHLDB2	1.23e-04	185	116	5	23579988036fc1925992c31919750f9b3fe9f790
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PREX2 PTPRB PLCXD3 FGD5 MCF2L	1.23e-04	185	116	5	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FILIP1 ARHGAP10 PREX2 DMD EPB41L2	1.27e-04	186	116	5	888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PREX2 PTPRB SACS FGD5 PHLDB2	1.27e-04	186	116	5	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	COL6A2 ROR1 PLXNA4 DMD PHLDB2	1.30e-04	187	116	5	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PREX2 PTPRB PLCXD3 FGD5 MCF2L	1.30e-04	187	116	5	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	critical-Myeloid-Monocyte-derived_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ARHGAP10 TRIM49D1 TGM1 CTSL MX1	1.30e-04	187	116	5	72e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEBL PREX2 PTPRB PLXNA4 FGD5	1.30e-04	187	116	5	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	PREX2 PTPRB PLCXD3 FGD5 MCF2L	1.30e-04	187	116	5	be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB2 PREX2 PTPRB TIAM1 FGD5	1.33e-04	188	116	5	0aa8747c2931b0c91f6d78bb2db8fd8ede6dd559
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	MYH7 NEBL ROR1 XIRP2 PLCXD3	1.33e-04	188	116	5	0758b474457efa36488e0195f7357100f4b6a090
Drug	Dapsone [80-08-0]; Up 200; 16.2uM; PC3; HT_HG-U133A	KMT2B NEBL ARHGAP10 RIF1 PTPN11 TIAM1 SMARCA2 EPB41L2 MX1	5.07e-07	194	112	9	1827_UP
Drug	Papaverine hydrochloride [61-25-6]; Down 200; 10.6uM; MCF7; HT_HG-U133A	ZXDC NEBL ZNF652 MSH3 INO80D TTC23 VAV3 MCF2L	5.79e-06	196	112	8	6245_DN
Disease	Maffucci Syndrome	IDH1 PTPN11	4.27e-05	3	112	2	C0024454
Disease	Enchondromatosis	IDH1 PTPN11	8.53e-05	4	112	2	C0014084
Disease	dilated cardiomyopathy (implicated_via_orthology)	MYH7 PTPN11 DMD CTSL	2.49e-04	80	112	4	DOID:12930 (implicated_via_orthology)
Disease	Paroxysmal atrial fibrillation	MYH7 NEBL ARHGAP10 PHLDB2 SORL1	3.30e-04	156	112	5	C0235480
Disease	familial atrial fibrillation	MYH7 NEBL ARHGAP10 PHLDB2 SORL1	3.30e-04	156	112	5	C3468561
Disease	Persistent atrial fibrillation	MYH7 NEBL ARHGAP10 PHLDB2 SORL1	3.30e-04	156	112	5	C2585653
Disease	Atrial Fibrillation	MYH7 NEBL ARHGAP10 PHLDB2 SORL1	3.70e-04	160	112	5	C0004238
Disease	sleep latency	SLC6A2 MALRD1 VAV3	3.76e-04	37	112	3	EFO_0005280
Disease	Ependymoblastoma	PMS2 SMO	3.94e-04	8	112	2	C0700367
Disease	Neuroectodermal Tumor, Primitive	PMS2 SMO	3.94e-04	8	112	2	C0206663
Disease	Cerebral Primitive Neuroectodermal Tumor	PMS2 SMO	3.94e-04	8	112	2	C0751675
Disease	Spongioblastoma	PMS2 SMO	3.94e-04	8	112	2	C0334584
Disease	Medulloepithelioma	PMS2 SMO	3.94e-04	8	112	2	C0334596
Disease	valine measurement	AARS1 MALRD1 BPI	4.75e-04	40	112	3	EFO_0009792
Disease	Glioma	ELP1 IDH1	5.05e-04	9	112	2	cv:C0017638
Disease	dilated cardiomyopathy (is_implicated_in)	MYH7 NEBL DMD	5.88e-04	43	112	3	DOID:12930 (is_implicated_in)
Disease	hereditary spastic paraplegia (implicated_via_orthology)	ATP13A5 KIF5A MX1	5.88e-04	43	112	3	DOID:2476 (implicated_via_orthology)
Disease	Familial dilated cardiomyopathy	MYH7 NEBL DMD	6.29e-04	44	112	3	C0340427
Disease	coronary artery disease, factor VII measurement	MIA3 ZNF652 APOB MCF2L	8.62e-04	111	112	4	EFO_0001645, EFO_0004619
Disease	Clear Cell Meningioma	SMO CTSL	9.19e-04	12	112	2	C0431121
Disease	Intraventricular Meningioma	SMO CTSL	9.19e-04	12	112	2	C1334271
Disease	Benign Meningioma	SMO CTSL	9.19e-04	12	112	2	C0281784
Disease	Intraorbital Meningioma	SMO CTSL	9.19e-04	12	112	2	C1334261
Disease	Olfactory Groove Meningioma	SMO CTSL	9.19e-04	12	112	2	C1335107
Disease	Angioblastic Meningioma	SMO CTSL	9.19e-04	12	112	2	C1527197
Disease	Meningiomas, Multiple	SMO CTSL	9.19e-04	12	112	2	C0205834
Disease	Xanthomatous Meningioma	SMO CTSL	9.19e-04	12	112	2	C0457190
Disease	Angiomatous Meningioma	SMO CTSL	9.19e-04	12	112	2	C0334608
Disease	Psammomatous Meningioma	SMO CTSL	9.19e-04	12	112	2	C0334607
Disease	Fibrous Meningioma	SMO CTSL	9.19e-04	12	112	2	C0334606
Disease	Meningothelial meningioma	SMO CTSL	9.19e-04	12	112	2	C0334605
Disease	Hemangioblastic Meningioma	SMO CTSL	9.19e-04	12	112	2	C0334609
Disease	Transitional Meningioma	SMO CTSL	9.19e-04	12	112	2	C0334611
Disease	Hemangiopericytic Meningioma	SMO CTSL	9.19e-04	12	112	2	C0334610
Disease	Spinal Meningioma	SMO CTSL	9.19e-04	12	112	2	C0347515
Disease	Intracranial Meningioma	SMO CTSL	9.19e-04	12	112	2	C0349604
Disease	Papillary Meningioma	SMO CTSL	9.19e-04	12	112	2	C3163622
Disease	Malignant Meningioma	SMO CTSL	9.19e-04	12	112	2	C0259785
Disease	Sphenoid Wing Meningioma	SMO CTSL	9.19e-04	12	112	2	C1565951
Disease	Posterior Fossa Meningioma	SMO CTSL	9.19e-04	12	112	2	C1565950
Disease	Parasagittal Meningioma	SMO CTSL	9.19e-04	12	112	2	C0751304
Disease	Cerebral Convexity Meningioma	SMO CTSL	9.19e-04	12	112	2	C0751303
Disease	Microcystic meningioma	SMO CTSL	9.19e-04	12	112	2	C1384408
Disease	Secretory meningioma	SMO CTSL	9.19e-04	12	112	2	C1384406
Disease	factor VIII measurement, coronary artery disease	MIA3 STAB2 ZNF652 APOB	9.21e-04	113	112	4	EFO_0001645, EFO_0004630
Disease	von Willebrand factor measurement, coronary artery disease	MIA3 STAB2 ZNF652 APOB	1.08e-03	118	112	4	EFO_0001645, EFO_0004629
Disease	gallbladder cancer (is_implicated_in)	APOB LRP1B	1.08e-03	13	112	2	DOID:3121 (is_implicated_in)
Disease	factor VII activating protease measurement	SGSM1 MALRD1 USP32	1.21e-03	55	112	3	EFO_0009368
Disease	ovarian cancer (is_implicated_in)	PMS2 MUC16 APOB	1.27e-03	56	112	3	DOID:2394 (is_implicated_in)
Disease	response to efavirenz, virologic response measurement	MCFD2 CDCA2 TIAM1	1.41e-03	58	112	3	EFO_0006904, EFO_0006906
Disease	response to statin, LDL cholesterol change measurement	APOB EPB41L2	1.45e-03	15	112	2	EFO_0007804, GO_0036273
Disease	Cardiomyopathies	MYH7 NEBL PTPN11 DMD	1.55e-03	130	112	4	C0878544
Disease	severe acute respiratory syndrome, COVID-19	PMS2 DCAF8L2 LRP1B PREX2 MALRD1 CADPS DMD	1.62e-03	447	112	7	EFO_0000694, MONDO_0100096
Disease	glaucoma (implicated_via_orthology)	NMNAT3 PTPN11	1.87e-03	17	112	2	DOID:1686 (implicated_via_orthology)
Disease	Meningioma	SMO CTSL	2.34e-03	19	112	2	C0025286
Disease	Osteoarthritis of hip	FILIP1 SMO	2.59e-03	20	112	2	C0029410
Disease	atrial fibrillation	FILIP1 MYH7 NEBL ARHGAP10 PHLDB2 SORL1	2.97e-03	371	112	6	EFO_0000275
Disease	colorectal carcinoma (is_implicated_in)	MSH3 PTPRB	3.14e-03	22	112	2	DOID:0080199 (is_implicated_in)
Disease	hypertrophic cardiomyopathy (is_implicated_in)	MYH7 CTSL	3.14e-03	22	112	2	DOID:11984 (is_implicated_in)
Disease	interleukin 10 measurement	MIA3 NEBL ROR1	3.29e-03	78	112	3	EFO_0004750
Disease	DNA methylation	NEBL LRP1B SLC6A2 ARSB TIAM1 PLXNA4 SMARCA2 KIF5A	3.59e-03	656	112	8	GO_0006306
Disease	glioblastoma (is_implicated_in)	IDH1 PTPRB	3.73e-03	24	112	2	DOID:3068 (is_implicated_in)
Disease	nephrotic syndrome (biomarker_via_orthology)	APOB CTSL	3.73e-03	24	112	2	DOID:1184 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
HDYMQNIHGKEIDLL	AGAP3	406	Q96P47
GEIYNHKKMQQHFEF	ASNS	76	P08243
AQLAGENHFHVYMKG	ATP13A5	611	Q4VNC0
EHNTDFGAFKHLYML	C2orf69	176	Q8N8R5
SVEAVVYNGKEHNHM	AACS	206	Q86V21
MGQHYEEEKRALSHE	BEGAIN	81	Q9BUH8
QHNQEYREGKHSFTM	CTSL3P	6	Q5NE16
FSFNPEEMKHYLHSQ	ETV3	291	P41162
EYQKHMETFDQNVDH	DMD	1676	P11532
SYAHFGIHEEMLKDE	PRMT1	56	Q99873
HEKNTMGAQEAHIYV	OPALIN	91	Q96PE5
DMVHNHLGVTEKEYF	PTPN3	56	P26045
HHMFVLEQEEYKKEG	MYH7	491	P12883
GMFTFYHQGHELAKD	ARHGAP10	206	A1A4S6
MGQEHQYHSKIDELI	CADPS	1156	Q9ULU8
AHQCYHGFMKAVQEG	FBXO42	86	Q6P3S6
FTITNLQYEEDMHHP	MUC16	12861	Q8WXI7
LQYEEDMHHPGSRKF	MUC16	12866	Q8WXI7
ELEKNYSHQVGNYHM	MSH3	1016	P20585
HTFHRLEAGEQYQIM	PTPRB	961	P23467
NMYEVDHDHNDGGLL	LRP1B	4496	Q9NZR2
ELQLHYFKMHDYDGN	MCFD2	71	Q8NI22
NYKEAFQHEVAHEMP	DYDC2	156	Q96IM9
HDEINHVQKTYAEMD	KAT8	146	Q9H7Z6
QMGSEAHVNTCYKHF	MOB3A	176	Q96BX8
EDSLHHGSLFDQYML	DCAF8L2	566	P0C7V8
YHLQKMQDTGFNGED	FSIP2	301	Q5CZC0
LSMYGVDLHHAKDSE	EPB41L2	401	O43491
HDQKLFPYGEHLEMA	FAM86B1	276	Q8N7N1
MFDFLDEQADKHGIH	PLXNA4	1716	Q9HCM2
AYVEMLQHLNLDFHG	FGD5	906	Q6ZNL6
YHTGTFAQIHEMQDL	LONP1	186	P36776
MGQLYQEHHEEDFFL	GABARAP	91	O95166
QDISIAYGEHLMQEH	ELP1	986	O95163
FEDGHYKSVHSFMED	KMT2B	1456	Q9UMN6
ELVQYYMEHHGQLKE	PTPN11	76	Q06124
YMEHHGQLKEKNGDV	PTPN11	81	Q06124
EYDADHMAQLQRVHG	EXOC8	191	Q8IYI6
GAHHFMSEYLKQEES	MED26	506	O95402
IHQEMFNYNEHEVSK	PRPF39	316	Q86UA1
LSNEEAGHHFEQMLK	NUP155	1011	O75694
HTLGNENGHFMYLEA	MALRD1	1556	Q5VYJ5
DHFGYTKDDKHEQDM	APOB	736	P04114
FLAEYHEHQMKGKAF	HTRA4	361	P83105
TEEAHQMTHDGYLKL	FBH1	616	Q8NFZ0
AIHHEDLSFQKGDQM	HCK	91	P08631
GMYNQDKSIEDFAHS	IDH1	181	O75874
NMDRHHYETFEKFGN	FAM20C	456	Q8IXL6
LDVQMKGEFYSENHH	BPI	251	P17213
MDIDVSYKHKGALHN	C5	1311	P01031
DMFHEKHESENLYSI	COL6A2	761	P12110
LFGNMEEIYHFHNRI	MCF2L	681	O15068
HMHQGYDKYDVSEFC	CDCA2	646	Q69YH5
DFIQDKNRHHYAGMV	ARSB	256	P15848
NLEKEMAHLNHDLYS	CEP192	631	Q8TEP8
PEHYAMEDKQHGEFA	GEN1	421	Q17RS7
MYEGKHIHFSEVDNK	INO80D	1	Q53TQ3
IFNHIYSMDENLEFH	KIF5A	116	Q12840
HTHFQQMIDKYINEA	CEP295	2041	Q9C0D2
GHQYKHQGMFQALTE	SLC25A35	141	Q3KQZ1
ATDNHVHSMLKYLDD	SCARA3	366	Q6AZY7
YGFMHDHLNEGKDSF	SACS	1256	Q9NZJ4
DQHHFYLALDNEMIV	PHKA2	526	P46019
HEDHMVNLRYGFTKE	PPEF2	241	O14830
LGSFIDHVHKEMDYF	TMEM67	881	Q5HYA8
HMYLELVYNQHENEA	TAF5	246	Q15542
GYMAHEHKVNIEDVA	SLC6A2	366	P23975
KHFNESRGYEIHMFD	SORL1	2051	Q92673
AEYQKMPAFHHEEEK	TRIM49	181	P0CI25
ADYYEQMFQSVLKHH	TEX47	66	Q8TBZ9
MFQHIEESFAEHLGY	SMARCA2	1021	P51531
SLDEEFFHHKAMQGT	MIA3	686	Q5JRA6
YELENEKHKHTDYMN	FILIP1	181	Q7Z7B0
QEGHSMGVYDIAFHQ	PRPF4	361	O43172
EDLHNYSGSQLFEMH	RIF1	2431	Q5UIP0
FHLIDHEAMSQGYVQ	MTF1	81	Q14872
GMEEHNLYAINFIHA	MTR	546	Q99707
ESYLHNHFIGEGMTK	TENT5D	281	Q8NEK8
KGHSGAVMELHYNTD	SNRNP40	106	Q96DI7
MNHMYEDNDKDVVHG	SGO2	626	Q562F6
DQEHGHKENKMSYQS	SEMG2	456	Q02383
AGMYHVFDQHVDEAV	WDR13	161	Q9H1Z4
HQQMSEGHRQKSEFY	PHLDB2	961	Q86SQ0
RHIQQYHMEDSEIKG	OS9	126	Q13438
LHNQEYREGKHSFTM	CTSL	61	P07711
EFNHHLESIMDKAYI	CNGB3	336	Q9NQW8
AGMEYLSSHFFVHKD	ROR1	601	Q01973
VFDNVGHLIRYHMDN	SHC4	586	Q6S5L8
TYELRNDHQKMEGFH	XIRP2	1951	A4UGR9
HKEVVFLDFNHFYGM	PLCXD3	136	Q63HM9
AHEQDTKMHEIYKGN	UHRF1BP1L	661	A0JNW5
TVYNLKAHMKGHEQE	ZXDC	251	Q2QGD7
MGNAESQHVEHEFYG	TIAM1	1	Q13009
DDVGKDVYHHTFFEM	AARS1	86	P49588
AHQLVHEGYKFMFDE	PPP6C	236	O00743
AEYQKMPAFHHEEEK	TRIM49C	181	P0CI26
MYEEINQFLHHKSSN	ZBED8	346	Q8IZ13
SNFAYVKHEAGIDDM	SCN8A	1671	Q9UQD0
IEHHLANVSMFFYND	STAB2	2376	Q8WWQ8
DNGFMHHVLEKSEFK	PREX2	541	Q70Z35
ELFELMHQNGDYTHF	SGSM1	1036	Q2NKQ1
EHQDMHSYIAAFGAV	SMO	226	Q99835
HEMIHAYLFVTNNDK	SPRTN	111	Q9H040
HATDEKYNFEMLQQH	PMS2	701	P54278
AEYHKMVAFFHEEEQ	TRIM51G	181	A0A3B3IT33
AQKHYHDALNIIDMA	TTC7B	561	Q86TV6
AEYQKMPAFHHEEEK	TRIM49D1	181	C9J1S8
YFDENMKPLEHLNHD	TGM1	416	P22735
EHHDVAEQYFQESMA	TTC23	286	Q5W5X9
AEYQKMPAFHHEEEK	TRIM49B	181	A6NDI0
QYFDEHMKTHTGEKP	ZNF652	426	Q9Y2D9
FQSYDLDHMEKKDHS	NAE1	196	Q13564
ESYLQAHMRTHNGEK	ZNF426	236	Q9BUY5
HDTTKMGHLTLEDYQ	USP32	326	Q8NFA0
SGSHLIQHQKMYTDE	ZNF850	236	A8MQ14
PDYADSNFHDFKMHT	VAV3	506	Q9UKW4
EIFQHLMAYHQEASK	MX1	576	P20591
NKGMYHFDADAVEHL	NEBL	311	O76041
AQNHISMVKYHEDFE	NEBL	776	O76041
HYEDTKANVHIPNDM	NEB	4536	P20929
FEVARDHLHQTGMYQ	NMNAT3	26	Q96T66