Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnatural killer cell lectin-like receptor binding

RAET1G ULBP2 RAET1L

3.61e-0517773GO:0046703
GeneOntologyMolecularFunctionglucokinase activity

HK2 HK3

1.46e-045772GO:0004340
GeneOntologyMolecularFunctionhexokinase activity

HK2 HK3

1.46e-045772GO:0004396
GeneOntologyMolecularFunctionfructokinase activity

HK2 HK3

1.46e-045772GO:0008865
GeneOntologyBiologicalProcesssusceptibility to natural killer cell mediated cytotoxicity

RAET1G ULBP2 RAET1L

4.13e-069773GO:0042271
GeneOntologyBiologicalProcesspositive regulation of macrophage activation

KARS1 RAET1G ULBP2 RAET1L

1.80e-0542774GO:0043032
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent

RAET1G ULBP2 RAET1L

2.71e-0516773GO:0002486
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway

RAET1G ULBP2 RAET1L

3.28e-0517773GO:0002484
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class Ib

RAET1G ULBP2 RAET1L

3.28e-0517773GO:0002476
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen via MHC class Ib

RAET1G ULBP2 RAET1L

3.92e-0518773GO:0002428
GeneOntologyBiologicalProcessosteoclast development

CLDN18 PAFAH1B1 SLC9B2

7.32e-0522773GO:0036035
GeneOntologyBiologicalProcessbone cell development

CLDN18 PAFAH1B1 SLC9B2

7.32e-0522773GO:0098751
GeneOntologyBiologicalProcesscellular response to exogenous dsRNA

RAET1G ULBP2 RAET1L

7.32e-0522773GO:0071360
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen via MHC class I

RAET1G ULBP2 RAET1L

8.40e-0523773GO:0019885
GeneOntologyBiologicalProcesspositive regulation of nitric oxide biosynthetic process

AGT RAET1G ULBP2 RAET1L

1.02e-0465774GO:0045429
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous peptide antigen

RAET1G ULBP2 RAET1L

1.08e-0425773GO:0002483
GeneOntologyBiologicalProcessantigen processing and presentation via MHC class Ib

RAET1G ULBP2 RAET1L

1.08e-0425773GO:0002475
GeneOntologyBiologicalProcesscarbohydrate phosphorylation

HK2 HK3 GNPTG

1.08e-0425773GO:0046835
GeneOntologyBiologicalProcesspositive regulation of nitric oxide metabolic process

AGT RAET1G ULBP2 RAET1L

1.15e-0467774GO:1904407
GeneOntologyBiologicalProcesscellular response to dsRNA

RAET1G ULBP2 RAET1L

1.53e-0428773GO:0071359
GeneOntologyBiologicalProcesspositive regulation of response to tumor cell

RAET1G ULBP2 RAET1L

1.53e-0428773GO:0002836
GeneOntologyBiologicalProcesspositive regulation of immune response to tumor cell

RAET1G ULBP2 RAET1L

1.53e-0428773GO:0002839
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous antigen

RAET1G ULBP2 RAET1L

2.30e-0432773GO:0019883
GeneOntologyBiologicalProcessregulation of macrophage activation

KARS1 RAET1G ULBP2 RAET1L

2.40e-0481774GO:0043030
GeneOntologyBiologicalProcesspositive regulation of natural killer cell activation

RAET1G ULBP2 RAET1L

3.00e-0435773GO:0032816
GeneOntologyBiologicalProcesspositive regulation of natural killer cell mediated cytotoxicity

RAET1G ULBP2 RAET1L

4.47e-0440773GO:0045954
GeneOntologyBiologicalProcessregulation of nitric oxide biosynthetic process

AGT RAET1G ULBP2 RAET1L

4.78e-0497774GO:0045428
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen via MHC class I

RAET1G ULBP2 RAET1L

4.81e-0441773GO:0002474
GeneOntologyBiologicalProcesspositive regulation of T cell mediated cytotoxicity

RAET1G ULBP2 RAET1L

5.17e-0442773GO:0001916
GeneOntologyBiologicalProcessfluid transport

CLDN18 SLC14A1 AQP6

5.17e-0442773GO:0042044
GeneOntologyBiologicalProcessregulation of nitric oxide metabolic process

AGT RAET1G ULBP2 RAET1L

5.37e-04100774GO:0080164
GeneOntologyBiologicalProcesspositive regulation of natural killer cell mediated immunity

RAET1G ULBP2 RAET1L

5.93e-0444773GO:0002717
DomainMHC_I

RAET1G ULBP2 RAET1L

8.17e-0521763PF00129
DomainMHC_I_a_a1/a2

RAET1G ULBP2 RAET1L

8.17e-0521763IPR001039
Domain-

RAET1G ULBP2 RAET1L

1.23e-04247633.30.500.10
DomainMHC_I-like_Ag-recog

RAET1G ULBP2 RAET1L

1.23e-0424763IPR011161
DomainHexokinase_C

HK2 HK3

1.62e-045762IPR022673
DomainHexokinase_N

HK2 HK3

1.62e-045762IPR022672
DomainHexokinase_1

HK2 HK3

1.62e-045762PF00349
DomainHexokinase_2

HK2 HK3

1.62e-045762PF03727
DomainHEXOKINASE_2

HK2 HK3

1.62e-045762PS51748
DomainHexokinase_BS

HK2 HK3

1.62e-045762IPR019807
DomainHEXOKINASE_1

HK2 HK3

1.62e-045762PS00378
DomainHexokinase

HK2 HK3

2.43e-046762IPR001312
DomainC1Q

C1QL1 C1QL2 C1QL3

2.95e-0432763SM00110
DomainC1q

C1QL1 C1QL2 C1QL3

2.95e-0432763PF00386
DomainC1q_dom

C1QL1 C1QL2 C1QL3

3.54e-0434763IPR001073
DomainC1Q

C1QL1 C1QL2 C1QL3

3.54e-0434763PS50871
DomainMHC_I/II-like_Ag-recog

RAET1G ULBP2 RAET1L

4.93e-0438763IPR011162
Domain-

C1QL1 C1QL2 C1QL3

1.11e-03507632.60.120.40
DomainuDENN

DENND2B DENND3

1.66e-0315762PF03456
DomainTumour_necrosis_fac-like_dom

C1QL1 C1QL2 C1QL3

1.70e-0358763IPR008983
DomainIG_MHC

RAET1G ULBP2 RAET1L

1.88e-0360763PS00290
DomainUDENN

DENND2B DENND3

1.89e-0316762PS50946
DomainDDENN

DENND2B DENND3

1.89e-0316762PS50947
DomainDENN

DENND2B DENND3

1.89e-0316762SM00799
DomaindDENN

DENND2B DENND3

1.89e-0316762SM00801
DomainDENN

DENND2B DENND3

1.89e-0316762PF02141
DomaindDENN_dom

DENND2B DENND3

1.89e-0316762IPR005112
DomainuDENN_dom

DENND2B DENND3

1.89e-0316762IPR005113
DomaindDENN

DENND2B DENND3

1.89e-0316762PF03455
DomainDENN

DENND2B DENND3

1.89e-0316762PS50211
DomainDENN_dom

DENND2B DENND3

1.89e-0316762IPR001194
DomainWD40

PIK3R4 WDR7 PAFAH1B1 ARPC1B DENND3

4.09e-03259765PF00400
DomainWD40_repeat_CS

PIK3R4 WDR7 PAFAH1B1 DENND3

4.50e-03164764IPR019775
DomainRicin_B_lectin

GALNT9 GALNT5

4.61e-0325762PF00652
DomainWD40

PIK3R4 WDR7 PAFAH1B1 ARPC1B DENND3

4.73e-03268765SM00320
DomainWD40_repeat

PIK3R4 WDR7 PAFAH1B1 ARPC1B DENND3

5.03e-03272765IPR001680
DomainCollagen

C1QL1 C1QL2 C1QL3

5.03e-0385763IPR008160
DomainCollagen

C1QL1 C1QL2 C1QL3

5.03e-0385763PF01391
Domain-

KLHL12 KLHL18

5.37e-03277622.130.10.80
DomainWD_REPEATS_1

PIK3R4 WDR7 PAFAH1B1 ARPC1B DENND3

5.51e-03278765PS00678
DomainWD_REPEATS_2

PIK3R4 WDR7 PAFAH1B1 ARPC1B DENND3

5.59e-03279765PS50082
DomainWD_REPEATS_REGION

PIK3R4 WDR7 PAFAH1B1 ARPC1B DENND3

5.59e-03279765PS50294
DomainRICIN

GALNT9 GALNT5

5.77e-0328762SM00458
DomainRICIN_B_LECTIN

GALNT9 GALNT5

5.77e-0328762PS50231
Pubmed

Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.

RAET1G ULBP2 RAET1L

1.04e-08377325212604
Pubmed

Direct interaction of the mouse cytomegalovirus m152/gp40 immunoevasin with RAE-1 isoforms.

RAET1G ULBP2 RAET1L

4.17e-08477320166740
Pubmed

Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: a novel cDNA family encodes cell surface proteins sharing partial homology with MHC class I molecules.

RAET1G ULBP2 RAET1L

4.17e-0847738882725
Pubmed

Cutting edge: tumor rejection mediated by NKG2D receptor-ligand interaction is dependent upon perforin.

RAET1G ULBP2 RAET1L

4.17e-08477312421908
Pubmed

NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules.

RAET1G ULBP2 RAET1L

4.17e-08477312756263
Pubmed

Murine NKG2D ligands: "double, double toil and trouble".

RAET1G ULBP2 RAET1L

4.17e-08477319081632
Pubmed

MULT1E/mIL-12: a novel bifunctional protein for natural killer cell activation.

RAET1G ULBP2 RAET1L

1.04e-07577324572784
Pubmed

The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins.

C1QL1 C1QL2 C1QL3

1.04e-07577321262840
Pubmed

Genomic structures and characterization of Rae1 family members encoding GPI-anchored cell surface proteins and expressed predominantly in embryonic mouse brain.

RAET1G ULBP2 RAET1L

1.04e-0757738982867
Pubmed

Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D.

RAET1G ULBP2 RAET1L

2.08e-07677311825567
Pubmed

Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.

RAET1G ULBP2 RAET1L

2.08e-07677320219610
Pubmed

The NKG2D ligands RAE-1δ and RAE-1ε differ with respect to their receptor affinity, expression profiles and transcriptional regulation.

RAET1G ULBP2 RAET1L

2.08e-07677320976056
Pubmed

Distinct expression of C1q-like family mRNAs in mouse brain and biochemical characterization of their encoded proteins.

C1QL1 C1QL2 C1QL3

2.08e-07677320525073
Pubmed

Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice.

RAET1G ULBP2 RAET1L

2.08e-07677310894171
Pubmed

Polymorphisms of NKG2D ligands: diverse RAET1/ULBP genes in northeastern Thais.

RAET1G ULBP2 RAET1L

2.08e-07677319688209
Pubmed

Ligands for murine NKG2D display heterogeneous binding behavior.

RAET1G ULBP2 RAET1L

2.08e-07677311857333
Pubmed

The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60.

RAET1G ULBP2 RAET1L

3.63e-07777316831899
Pubmed

Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase.

RAET1G ULBP2 RAET1L

3.63e-07777320870941
Pubmed

Critical role of the NKG2D receptor for NK cell-mediated control and immune escape of B-cell lymphoma.

RAET1G ULBP2 RAET1L

3.63e-07777326151313
Pubmed

NKG2D and Its Ligand MULT1 Contribute to Disease Progression in a Mouse Model of Multiple Sclerosis.

RAET1G ULBP2 RAET1L

3.63e-07777330787931
Pubmed

Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D.

RAET1G ULBP2 RAET1L

3.63e-07777312370332
Pubmed

NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery.

RAET1G ULBP2 RAET1L

3.63e-07777325583577
Pubmed

A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity.

RAET1G ULBP2 RAET1L

5.80e-07877312645935
Pubmed

Gut microbiota regulates NKG2D ligand expression on intestinal epithelial cells.

RAET1G ULBP2 RAET1L

8.68e-07977323136011
Pubmed

Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor.

RAET1G ULBP2 RAET1L

8.68e-07977314764662
Pubmed

A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3.

RAET1G ULBP2 RAET1L

1.24e-061077311827464
Pubmed

Cell Surface Downregulation of NK Cell Ligands by Patient-Derived HIV-1 Vpu and Nef Alleles.

RAET1G ULBP2 RAET1L

1.70e-061177326656785
Pubmed

Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy.

FASN FN1 AGT

2.26e-061277324717294
Pubmed

Outcome of lumbar epidural steroid injection is predicted by assay of a complex of fibronectin and aggrecan from epidural lavage.

FN1 ACAN

4.84e-06277221224775
Pubmed

[Evaluation of Gene Expression of Hexokinases in Colorectal Cancer with the Use of Bioinformatics Methods].

HK2 HK3

1.45e-05377226855992
Pubmed

Isolation and proteomic characterization of human Parvulin-associating preribosomal ribonucleoprotein complexes.

FN1 PIN4

1.45e-05377211960984
Pubmed

Maternal endothelial damage as a disorder shared by early preeclampsia, late preeclampsia and intrauterine growth restriction.

FN1 PGF

1.45e-05377227865093
Pubmed

Antitumor effects of a drug combination targeting glycolysis, glutaminolysis and de novo synthesis of fatty acids.

FASN HK2

1.45e-05377226134042
Pubmed

C1ql1 is expressed in adult outer hair cells of the cochlea in a tonotopic gradient.

C1QL1 C1QL3

1.45e-05377233979385
Pubmed

Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism.

HK2 HK3

2.89e-05477225904018
Pubmed

High 18F-FDG uptake in PMAH correlated with normal expression of Glut1, HK1, HK2, and HK3.

HK2 HK3

2.89e-05477225766729
Pubmed

C1q/tumor necrosis factor-related protein 11 (CTRP11), a novel adipose stroma-derived regulator of adipogenesis.

C1QL1 C1QL2

2.89e-05477223449976
Pubmed

Differential NKG2D binding to highly related human NKG2D ligands ULBP2 and RAET1G is determined by a single amino acid in the alpha2 domain.

RAET1G ULBP2

2.89e-05477219424970
Pubmed

Anterograde C1ql1 signaling is required in order to determine and maintain a single-winner climbing fiber in the mouse cerebellum.

C1QL1 C1QL2

2.89e-05477225611509
Pubmed

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function.

FASN HK2 HK3

4.06e-053077327133129
Pubmed

Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1.

FN1 ACAN

4.82e-05577216061471
Pubmed

Linkage of the gene for uncoupling protein to esterase-1,2 and haptoglobin in the rat.

CES1 AGT

4.82e-0557728228167
Pubmed

Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins.

C1QL2 C1QL3

4.82e-05577227133466
Pubmed

ULBP6/RAET1L is an additional human NKG2D ligand.

RAET1G RAET1L

4.82e-05577219658097
Pubmed

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

GAD2 FASN AGT APOL5 GNAO1

6.97e-0519277520602615
Pubmed

Identifying strategies to target the metabolic flexibility of tumours.

FASN HK2

7.22e-05677232694609
Pubmed

Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin.

HK2 FN1 SDHC

9.72e-054077338418556
Pubmed

Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models.

C1QL2 GAD2

1.01e-04777234197733
Pubmed

Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C.

TMEM67 DNAJC10

1.01e-04777219815549
Pubmed

A disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand binding.

ULBP2 RAET1L

1.01e-04777228559451
Pubmed

Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.

FASN FN1 AGT

1.29e-044477331273033
Pubmed

ABO, Rh, MNS, Duffy, Kidd,Yt, Scianna, and Colton blood group systems in indigenous Chinese.

SLC14A1 ERMAP

1.34e-04877215783300
Pubmed

Progressive development of renal cysts in glycogen storage disease type I.

FN1 AGT

1.34e-04877227436577
Pubmed

Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the N-terminal half of type III hexokinase.

HK2 HK3

1.34e-04877211068878
Pubmed

Expression of hexokinases and glucose transporters in treated and untreated oesophageal adenocarcinoma.

HK2 HK3

1.72e-04977219554504
Pubmed

Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities.

FN1 ACAN

1.72e-04977215296947
Pubmed

Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice.

HK2 HK3

1.72e-04977221074528
Pubmed

Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development.

FN1 ACAN

2.63e-041177238750698
Pubmed

Xylosyltransferase I mediates the synthesis of proteoglycans with long glycosaminoglycan chains and controls chondrocyte hypertrophy and collagen fibers organization of in the growth plate.

XYLT1 ACAN

3.71e-041377237296099
Pubmed

An analysis of expression patterns of genes encoding proteins with catalytic activities.

HK2 HK3 SDHC

4.51e-046777317626619
Pubmed

Muscleblind-like 1 is required for normal heart valve development in vivo.

FN1 ACAN

4.99e-041577226472242
Pubmed

Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation.

FN1 ACAN

4.99e-041577238018454
Pubmed

Expression of LIM-homeodomain transcription factors in the developing and mature mouse retina.

GAD2 GNAO1

5.69e-041677224333658
Pubmed

Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.

FN1 ACAN

7.23e-041877235503090
Pubmed

Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs.

FN1 ACAN

7.23e-041877212571105
Pubmed

A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).

FN1 AGT PAFAH1B1 PGF

7.90e-0418677420673868
Pubmed

Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.

FN1 AGT PAFAH1B1 PGF

7.90e-0418677420452482
Pubmed

Purification and Transcriptomic Analysis of Mouse Fetal Leydig Cells Reveals Candidate Genes for Specification of Gonadal Steroidogenic Cells.

SLC6A18 ERMAP

8.07e-041977225855264
Pubmed

Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6.

FN1 PIN4 MAP3K12

8.44e-048377320029029
Pubmed

BMP-Responsive Protease HtrA1 Is Differentially Expressed in Astrocytes and Regulates Astrocytic Development and Injury Response.

FN1 ACAN

8.96e-042077229483282
Pubmed

A series of recombinant inbred strains between the BALB/cHeA and STS/A mouse strains.

CES1 HAO1

9.89e-04217724042679
Pubmed

Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.

FN1 ACAN

1.09e-032277227527664
Pubmed

Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans.

ACAN GALNT5

1.09e-032277225107907
Pubmed

MATH5 controls the acquisition of multiple retinal cell fates.

GAD2 GNAO1

1.09e-032277221087508
Pubmed

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.

HK2 HK3 SDHC

1.17e-039377327215380
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

HK2 CES1 PAFAH1B1 KLHL12 GALNT5 MAPK4 KLHL18

1.18e-0373077734857952
Pubmed

GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.

C1QL1 THADA

1.19e-032377223725790
Pubmed

Loss of the disease-associated glycosyltransferase Galnt3 alters Muc10 glycosylation and the composition of the oral microbiome.

GALNT9 GALNT5

1.29e-032477231882545
Pubmed

Requirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retina.

GAD2 GNAO1

1.29e-032477217092954
Pubmed

Developmental abnormalities in cortical GABAergic system in mice lacking mGlu3 metabotropic glutamate receptors.

GAD2 ACAN

1.40e-032577231665922
Pubmed

The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.

THADA FN1 MAP3K12

1.40e-039977319730683
Pubmed

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.

GAD2 FASN MOXD1 SLC14A1 ARL5A

1.50e-0337677524154525
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

FN1 ACAN

1.52e-032677234189436
Pubmed

Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice.

XYLT1 ACAN

1.52e-032677233905568
Pubmed

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes.

HK2 PRXL2A MRPL19 PLPBP SDHC

1.61e-0338277529222160
Pubmed

Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.

FN1 ACAN

1.64e-032777235894043
Pubmed

Human gingiva transcriptome during wound healing.

HK3 FN1 AGT

1.76e-0310777328005267
Pubmed

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.

HK2 HK3 SDHC

2.10e-0311477328245920
Pubmed

Genetic associations of brain structural networks in schizophrenia: a preliminary study.

FASN APOL5

2.16e-033177220691427
Pubmed

Defining developmental diversification of diencephalon neurons through single cell gene expression profiling.

C1QL2 GAD2

2.16e-033177230872278
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

FASN KARS1 HK2 HK3 PRXL2A MRPL19 PLPBP SDHC

2.21e-03104777818614015
GeneFamilyEndogenous ligands|C1q and TNF related

C1QL1 C1QL2 C1QL3

2.34e-05185731372
GeneFamilyOlfactory receptors, family 10

OR10H5 OR10H2 OR10H1

1.18e-0366573157
GeneFamilyWD repeat domain containing

PIK3R4 WDR7 PAFAH1B1 ARPC1B DENND3

1.39e-03262575362
GeneFamilyPolypeptide N-acetylgalactosaminyltransferases

GALNT9 GALNT5

1.79e-0320572433
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND2B DENND3

2.80e-0325572504
GeneFamilyGlycosyltransferase family 6|Blood group antigens

SLC14A1 ERMAP

6.06e-0337572454
GeneFamilyKelch like|BTB domain containing

KLHL12 KLHL18

7.75e-0342572617
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

THADA ARMCX6

8.12e-0343572409
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

QRFP HK2 SLC14A1 AGT PRXL2A MAPK4

6.84e-071797767ae67e1c09a4ce9b3bcec4c48ee9cf2b1cb4e339
ToppCellTracheal-10x5prime-Stromal-Chondrocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

XYLT1 MOXD1 FN1 SLC14A1 ACAN GALNT9

1.23e-06198776c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCellTracheal-10x5prime-Stromal-Chondrocytic-Chondrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

XYLT1 MOXD1 FN1 SLC14A1 ACAN GALNT9

1.23e-0619877655f013e9e6587d9ece59751fa131b1d22d6cceea
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FASN FN1 SIGMAR1 AGT HAO1

9.96e-06165775d449a568664a81d9b5538e8f409301448a32ac37
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CLDN18 GALNT5 MAPK4 RAB11FIP1 DENND3

1.48e-051797754f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

HK3 FN1 CES1 ECSCR OVCH1

1.60e-05182775a035d45fd512bee8dac38eb387dbf39f5a8a1fed
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLDN18 CES1 GALNT5 RAB11FIP1 DENND3

1.64e-05183775274483009b309289e4cb84beedf6806430db6ff6
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SAA4 SLC14A1 AGT GALNT5 HAO1

1.92e-051897757899af78b273d9c7f029d52f7e0cf6df4da41f5e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 MOXD1 FN1 SLC14A1 DENND2B

2.02e-05191775107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MOXD1 FN1 STARD9 ACAN DENND2B

2.02e-0519177504c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 MOXD1 FN1 SLC14A1 DENND2B

2.02e-05191775bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1|Hippocampus / BrainAtlas - Mouse McCarroll V32

TMEM217 SLC14A1 AGT PRXL2A

5.42e-0511977479342c491a214c870ff6215da613db4a28c9d587
ToppCellHippocampus-Macroglia-ASTROCYTE|Hippocampus / BrainAtlas - Mouse McCarroll V32

TMEM217 SLC14A1 AGT PRXL2A

5.42e-0511977436857095d4e4cc6428d13bf7de04daec1f4cde1e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDK17 FN1 SLC14A1 STARD9

1.47e-04154774e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D16 QRFP THADA SLC14A1

1.70e-0416077455f599df6e3b7a5a505df4b094c834281311d94a
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D16 QRFP THADA SLC14A1

1.70e-04160774296e53e1e0786346d38db2d4188b9a1c0430627b
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLDN18 FASN SLC9B2 RAB11FIP1

1.79e-0416277406f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLDN18 FASN SLC9B2 RAB11FIP1

1.79e-04162774d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCellCF-Myeloid-Alveolar_Macrophage|Myeloid / Disease state, Lineage and Cell class

FN1 CES1 RAET1G MRPL19

1.92e-0416577469ad83f2e4da62acfdf0a5a299d8444932a61160
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A18 GAD2 HK2 GNAO1

2.01e-041677745accd0bc7c95089feb2c09376d12cd8bd3773775
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1QL1 GAD2 CES1 C1QL3

2.05e-041687744e1b522c7400c9d87f63c00e4e1dd07136095cd6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 MOXD1 GNAO1 DENND2B

2.05e-04168774d19a115365c5415e51c039718d7669de788fcf33
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAD2 LHFPL5 GNAO1 GPR179

2.05e-0416877417d46f993dc4ae22b8087808582aba77f5c61892
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM67 HK3 C1QL3 GALNT9

2.25e-041727743f784aed340b50ddbec3f7dc0a5279180d38a2bb
ToppCelldroplet-Marrow-nan-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATG4A FN1 WDR7 SIGMAR1

2.30e-041737746d2ceba4f89a228600e2b40aba81bb0eb81578c0
ToppCellMacrophages-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

FN1 GNAO1 MAP3K12 ARPC1B

2.30e-04173774a112da5b0ab6e1f13d1a7dfa72c67c9a95fa9243
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

HK3 FN1 CES1 OVCH1

2.30e-041737744efa0878ed1ede8fa5d6c191a76d4f70558ba761
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC14A1 ECSCR PPP2R3B GNAO1

2.35e-0417477418ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 MOXD1 FN1 DENND2B

2.45e-041767749bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATG4A SLC14A1 ERMAP PRXL2A

2.45e-04176774fc51e4dcad5456c229d76fdcb9a80c4c79eacf3f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 MOXD1 FN1 DENND2B

2.45e-041767743f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CLDN18 FN1 RAB11FIP1 DENND3

2.45e-04176774f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCellControl-Epithelial_alveolar-AT_1-AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLDN18 CES1 GALNT5 DENND3

2.56e-041787741817bc520f3d23da8c0fa09bba50ae703a820cb1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 QRFP MOXD1 DENND2B

2.56e-04178774d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDK17 ECSCR STARD9 DENND3

2.61e-04179774327cc39161741ddbc4e8d45b9b3d30b3ce508929
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 XYLT1 C1QL2 ACAN

2.67e-04180774fa819df81fca95c2cc602fede635cb03e3f35fad
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 XYLT1 C1QL2 ACAN

2.67e-04180774907cd510fd2e21532ce04ba687e8894f7af71f27
ToppCellAT1_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

CLDN18 GALNT5 RAB11FIP1 DENND3

2.67e-04180774ff4728782c3ec814ba071cc22b7894abdd9da837
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

CLDN18 GALNT5 MAPK4 RAB11FIP1

2.84e-04183774942530449e9c6583705eeb8f6f12621daea57252
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLDN18 CES1 GALNT5 RAB11FIP1

2.84e-0418377406ac66726ec53db810ebb90ec69cfdb903da53f6
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

SLC6A18 GALNT5 MAPK4 DENND3

2.84e-041837746821dca076318115d360ff426eb1218cfe104063
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 XYLT1 C1QL2 ACAN

2.90e-04184774278a7ed764c326450cb70e69ed2175980eaf5fe0
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 XYLT1 C1QL2 ACAN

2.90e-041847748d86e125257ff1d3af8d90577a8b3f0321eca21c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 SLC14A1 AGT MAPK4

2.96e-04185774dbbd348714cd16a4948a04648e914b1e71e2a8ef
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 SLC14A1 AGT MAPK4

2.96e-04185774bea69058afa5aa927fe15c1f8d46460562ec4dd4
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLDN18 GALNT5 RAB11FIP1 DENND3

2.96e-04185774c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-B_cells-Pro-B|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIG4 TMEM217 PPP2R3B DENND3

3.02e-041867744a5264e32ba004ed58dc4102d84e4bc4dbbe1440
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLDN18 GALNT5 RAB11FIP1 DENND3

3.02e-041867743aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-B_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LIG4 TMEM217 PPP2R3B DENND3

3.02e-04186774528ee88f6e27863c7bcdffd4416cbbd83fc65e9d
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

CLDN18 MAPK4 RAB11FIP1 DENND3

3.02e-0418677409d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCelldroplet-Marrow-BM-30m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 SIGMAR1 GALNT9 OSGEP

3.02e-04186774bcb3ac9f9b51346e0a2b0bda96d149b3c11f7883
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJC10 SIGMAR1 ECSCR GALNT5

3.09e-04187774ab109aa51beae3df474c15002e70361f328cadad
ToppCellfacs-Large_Intestine-Distal-18m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJC10 SIGMAR1 ECSCR GALNT5

3.09e-04187774a4c408fc941d2e8a811a26aa916c0b3e3341163a
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

GALNT5 MAPK4 RAB11FIP1 DENND3

3.09e-0418777477f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellmetastatic_Brain-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

HK3 CES1 ECSCR ARPC1B

3.09e-041877747375f70a970a5d5a58b7c33ada2dcf6dcef525c6
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 XYLT1 C1QL2 ACAN

3.15e-041887747471c194276161422326647f09022e94f3d1640c
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-chondrocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

C1QL1 MOXD1 FN1 ACAN

3.15e-041887745a89587ee6f2b4dc14244bd88bb31efb81c50dbe
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL1 XYLT1 C1QL2 ACAN

3.15e-04188774053c251d3ddbeb866f34565aefca4535517b4387
ToppCellMacrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FN1 CES1 ECSCR OVCH1

3.21e-04189774c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D16 CDK17 DNAJC10 GALNT5

3.21e-041897745a0fd34928117f162c83ca1b068aa8f7069a6765
ToppCellNeuroendocrine-neuroendo-2-Calca|World / Class top

AGT LHFPL5 GNAO1 PGF

3.21e-041897746baa9a74560121cc008bb8fa9b2b7a335b3aeee0
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

CLDN18 GALNT5 RAB11FIP1 DENND3

3.21e-041897745a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 CDK17 MOXD1 DENND2B

3.28e-041907741121eb607a984c59fbffe7220837fc178745aa55
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SAA4 SLC14A1 AGT HAO1

3.28e-04190774a34293601aefe5fb5c400c14091294b9ddaa195b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 CDK17 MOXD1 DENND2B

3.28e-04190774048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

C1QL1 XYLT1 C1QL2 ACAN

3.28e-041907746c7e1086c0a274cd5527c3104106e372811c9905
ToppCelldroplet-Marrow-nan-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 SIGMAR1 GALNT9 OSGEP

3.28e-0419077495d8dc8488e95158e84a44bb53ea4ab7bf3d44bb
ToppCelldroplet-Marrow-nan-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 SIGMAR1 GALNT9 OSGEP

3.28e-04190774e2fdbfaf08da3274b6bdda615386aa880040a90a
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MOXD1 SAA4 FN1 CLCF1

3.28e-04190774ad0d9aed8c9c99551765d14730d70ebef1ea856b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 MOXD1 GNAO1 DENND2B

3.34e-04191774a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

FN1 CES1 ECSCR OVCH1

3.34e-041917744c4f50a502e3f6768a89df686fa2830b83b8b33f
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FN1 CES1 ECSCR OVCH1

3.34e-04191774de7c88bb46f794291025ef121a89fcd94dea4ffe
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 MOXD1 GNAO1 DENND2B

3.34e-041917748f6d592edc32fdb901af30501d4360512334e8c2
ToppCellNeuroendocrine|World / Class top

AGT LHFPL5 GNAO1 PGF

3.41e-041927740199da3ef9ddb6673e9aa41f346f374838aec182
ToppCellMonocytes-Tissue-resident_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

HK2 FN1 PRXL2A ARL5A

3.48e-04193774198552810dcac8d0ca63a78badd6702b49ff6edf
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

MOXD1 FN1 ACAN ARPC1B

3.48e-04193774e1de67ddada87229f5db0ec193a6da8745a86a64
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D16 CDK17 DNAJC10 GALNT5

3.48e-041937746a9bce5064938b5b84ad57b4fd4a7841afe100c8
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MOXD1 SAA4 FN1 CLCF1

3.48e-04193774a313541cedfcff8fb311b9bc60157359aa103830
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK17 DNAJC10 SIGMAR1 GALNT5

3.48e-041937744aee372ba2c0351b0221d0d468707d1ad21526d6
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ATG4A SLC14A1 ERMAP GALNT5

3.48e-04193774305e15ee467826ee08b2617c69f250ad39c11b19
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal-choroid_plexus/mesenchymal-like_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

MOXD1 FN1 ACAN ARPC1B

3.48e-04193774b6f5a85210e60798205eaf5884cdb540f549d08a
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK17 DNAJC10 SIGMAR1 GALNT5

3.48e-04193774aaa5042388dc451bff384c6bb237348f08280a08
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ATG4A SLC14A1 ERMAP GALNT5

3.48e-04193774dd376664906caccc9c2065f8e7a364509e18a5cc
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATG4A DNAJC10 SIGMAR1 GALNT5

3.55e-041947740797245ebfa389a6f66874cb0f11297f1456e600
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDK17 SLC14A1 ECSCR OVCH1

3.55e-04194774a429d22c8c9d0fd3bfa9f877a6364cecad68db30
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MOXD1 FN1 CES1 GNAO1

3.55e-041947745f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HK3 FN1 OVCH1 ARPC1B

3.55e-04194774412c2b8eb522da6c84f8b00d32d6f0bee555251f
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATG4A DNAJC10 SIGMAR1 GALNT5

3.55e-041947740241b4b88d6210b4c1b8aa99db17115b18142f01
ToppCellASK452-Endothelial-Lymphatic|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

STARD9 OSGEP KLHL18 ARL5A

3.62e-0419577420f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 MOXD1 FN1 DENND2B

3.62e-0419577449c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HK3 FN1 CES1 ARPC1B

3.62e-041957749e49e59a20b1bbd6167d594c33ab6bdfe2c1ebaf
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HK3 FN1 CES1 ARPC1B

3.62e-04195774412a9fcf9f075d97fae254bbd89774e4b1face07
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FN1 ECSCR PRXL2A ARPC1B

3.62e-041957749ad4981c4d157edc752de206ab0d754aa14beab8
ToppCellnormal_Lung-Epithelial_cells-AT1|normal_Lung / Location, Cell class and cell subclass

CLDN18 GALNT5 RAB11FIP1 DENND3

3.62e-04195774569d1ebc5a5aa110a2430b096755ae35354040c4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 MOXD1 FN1 DENND2B

3.62e-04195774dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CLDN18 GALNT5 RAB11FIP1 DENND3

3.69e-041967746731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 MOXD1 FN1 DENND2B

3.69e-04196774fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SAA4 CES1 GALNT5 CLCF1

3.69e-04196774b246e482f012dd9782b49c2a953acedfa3c1139d
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

C1QL1 XYLT1 C1QL2 ACAN

3.69e-04196774f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SAA4 CES1 GALNT5 CLCF1

3.69e-04196774808c0a7d1889a8f3508ed9790c6dc7ec16bbc840
Drug3-bromopyruvate

GAD2 HK2 HK3 SLC14A1 HAO1

8.34e-0752765CID000070684
Drug[(2S)-2-[(Z)-dodec-9-enoyl]oxy-3-tetradecanoyloxypropyl] [(2R,3R,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl] phosphate

LIG4 HK2 HK3 SLC14A1 AGT

1.72e-0660765CID011968289
Diseaselevel of UL16-binding protein 6 in blood serum

ULBP2 RAET1L

5.87e-062722OBA_2043185
Diseasehyperinsulinemic hypoglycemia (implicated_via_orthology)

HK2 HK3

5.84e-055722DOID:13317 (implicated_via_orthology)
DiseaseFocal glomerulosclerosis

FN1 AGT E2F3

9.39e-0536723C0017668
Diseasematurity-onset diabetes of the young (implicated_via_orthology)

HK2 HK3

2.61e-0410722DOID:0050524 (implicated_via_orthology)
DiseaseDiabetic Retinopathy

GAD2 AGT

3.18e-0411722C0011884
Diseasehyperglycemia (implicated_via_orthology)

HK2 HK3

7.80e-0417722DOID:4195 (implicated_via_orthology)
Diseaseage-related hearing impairment

XYLT1 THADA ACAN PAFAH1B1 GNAO1

1.19e-03324725EFO_0005782
Diseasepulmonary arterial hypertension

DNAJC10 TMEM217

1.31e-0322722EFO_0001361
DiseaseUreteral obstruction

FN1 AGT

1.57e-0324722C0041956
DiseaseLeft Ventricular Hypertrophy

FN1 AGT

1.70e-0325722C0149721
DiseaseVisual seizure

GAD2 SIGMAR1 AGT

1.96e-03101723C0270824
DiseaseEpileptic drop attack

GAD2 SIGMAR1 AGT

1.96e-03101723C0270846
DiseaseGeneralized seizures

GAD2 SIGMAR1 AGT

1.96e-03101723C0234533
DiseaseClonic Seizures

GAD2 SIGMAR1 AGT

1.96e-03101723C0234535
DiseaseVertiginous seizure

GAD2 SIGMAR1 AGT

1.96e-03101723C0422855
DiseaseGustatory seizure

GAD2 SIGMAR1 AGT

1.96e-03101723C0422854
DiseaseSeizures, Somatosensory

GAD2 SIGMAR1 AGT

1.96e-03101723C0422850
DiseaseOlfactory seizure

GAD2 SIGMAR1 AGT

1.96e-03101723C0422853
DiseaseSeizures, Auditory

GAD2 SIGMAR1 AGT

1.96e-03101723C0422852
DiseaseGeneralized Absence Seizures

GAD2 SIGMAR1 AGT

1.96e-03101723C4505436
DiseaseConvulsive Seizures

GAD2 SIGMAR1 AGT

1.96e-03101723C0751494
DiseaseSeizures, Sensory

GAD2 SIGMAR1 AGT

1.96e-03101723C0751496
DiseaseJacksonian Seizure

GAD2 SIGMAR1 AGT

1.96e-03101723C0022333
DiseaseNon-epileptic convulsion

GAD2 SIGMAR1 AGT

1.96e-03101723C0751056
DiseaseAtonic Absence Seizures

GAD2 SIGMAR1 AGT

1.96e-03101723C0751123
DiseaseComplex partial seizures

GAD2 SIGMAR1 AGT

1.96e-03101723C0149958
DiseaseSingle Seizure

GAD2 SIGMAR1 AGT

1.96e-03101723C0751110
DiseaseEpileptic Seizures

GAD2 SIGMAR1 AGT

1.96e-03101723C4317109
DiseaseNonepileptic Seizures

GAD2 SIGMAR1 AGT

1.96e-03101723C3495874
Diseaselissencephaly (implicated_via_orthology)

CDK17 PAFAH1B1

1.98e-0327722DOID:0050453 (implicated_via_orthology)
DiseaseTonic Seizures

GAD2 SIGMAR1 AGT

2.01e-03102723C0270844
DiseaseAbsence Seizures

GAD2 SIGMAR1 AGT

2.01e-03102723C4316903
DiseaseConvulsions

GAD2 SIGMAR1 AGT

2.01e-03102723C4048158
DiseaseSeizures

GAD2 KARS1 SIGMAR1 AGT

2.01e-03218724C0036572
DiseaseSeizures, Focal

GAD2 SIGMAR1 AGT

2.13e-03104723C0751495
DiseaseMyoclonic Seizures

GAD2 SIGMAR1 AGT

2.13e-03104723C4317123
DiseaseTonic - clonic seizures

GAD2 SIGMAR1 AGT

2.13e-03104723C0494475
DiseaseHyalinosis, Segmental Glomerular

FN1 AGT

2.13e-0328722C0086432
Diseaseglucose metabolism disease (implicated_via_orthology)

HK2 HK3

2.13e-0328722DOID:4194 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
MVWIHGGGLMVGAAS

CES1

136

P23141
AKHGRGMAVWTGGSM

ACTL10

201

Q5JWF8
GMAVWTGGSMVASLH

ACTL10

206

Q5JWF8
SDAGWGCMLRCGQMM

ATG4A

71

Q8WYN0
TGEGLCQGLEWMMSR

ARL5A

161

Q9Y689
HVLMRGGDGTSMWAD

C1QL3

176

Q5VWW1
CTTGMDGGMSIWDVK

ARPC1B

346

O15143
LMRGGDGTSMWADLC

C1QL1

181

O75973
MSMCGEKREGSGSEW

DENND2B

181

P78524
GGRLWCCTGNSIMVM

DENND3

1041

A2RUS2
EVGWMAAGLMIGAGA

ARMCX6

6

Q7L4S7
MQAVTGWKTGCSLMG

AGT

246

P01019
WFRCMDLDGDGALSM

PPP2R3B

396

Q9Y5P8
STGMCLMTLVGHDNW

PAFAH1B1

326

P43034
MHVDAAWGGGLLMSR

GAD2

361

Q05329
GCSWAGGLVMGMVVT

OR10H5

146

Q8NGA6
GCSWAGGSVMGMVVT

OR10H2

146

O60403
AGSMGSRMAELCQWE

GPR179

2211

Q6PRD1
DMWAAGCILAEMLTG

MAPK4

211

P31152
LGMRVWQCGGSMEVL

GALNT9

356

Q9HCQ5
AWMQLAAATGLMIGC

LHFPL5

131

Q8TAF8
GRMCVNMEWGAFGDN

HK2

701

P52789
ARQGGDLGWMTRGSM

PIN4

76

Q9Y237
CGLMTAFSWILGSMD

OR2M5

141

A3KFT3
RACQSLGTGMMLSSW

HAO1

96

Q9UJM8
GGRMVVTCMEQAGGW

MROH6

316

A6NGR9
DMWGVGCIFFEMASG

CDK17

371

Q00537
RMTMSCWLLGAADGL

OR2T33

141

Q8NG76
GAMIAQAGWEMFRAG

OSGEP

296

Q9NPF4
SGRMCINMEWGAFGD

HK3

706

P52790
QAGMDMCSAGWLADR

ACAN

291

P16112
MGGLGAGERWADLAM

QRFP

31

P83859
NTFTGMWMRDGDACR

GNPTG

116

Q9UJJ9
WSMLGDMQTAREGAG

KLHL12

406

Q53G59
WTFMAPMACHEGGVG

KLHL18

551

O94889
WMGCSLSEDGGMLAQ

E2F3

241

O00716
WGKGSRGGMMSHFLC

LIG4

471

P49917
MRGGDGTSMWADLCK

C1QL2

211

Q7Z5L3
MDAVEPGGRGWASML

AQP6

1

Q13520
QGWMMVDCTCLGEGS

FN1

206

P02751
GGENMELSFKVWMCG

GALNT5

696

Q7Z7M9
WSLPMAMSICHRGTG

SDHC

61

Q99643
MGTAGAMQLCWVILG

ECSCR

1

Q19T08
SLLVDWSMGIAGGMN

MAP3K12

211

Q12852
GMLDGLVNVGWMDCA

DNAJC10

281

Q8IXB1
CSGMGTQWRGMGLSL

FASN

496

P49327
GVGDMGRAYWDIMIS

SAA4

31

P35542
LGLAGCIAATGMDMW

CLDN18

16

P56856
GCSWAGGLVMGMVVT

OR10H1

146

Q9Y4A9
MATRGGAGVAMAVWS

TMEM67

1

Q5HYA8
MEMASSAGSWLSGCL

ERMAP

1

Q96PL5
MSLMVSAGRGLGAVW

RAB11FIP1

1

Q6WKZ4
AMLDWQNGSMGRSGE

THADA

316

Q6YHU6
GWGMGIDRVAMFLTD

KARS1

546

Q15046
LGRTMLCAGFPDWGM

OVCH1

216

Q7RTY7
SAMMRLWGDSGIQEC

GNAO1

126

P09471
SLGQAVNCWSGMGMS

PRDM7

376

Q9NQW5
CTLVMAFLAGMGWTS

SLC9B2

366

Q86UD5
AGGWMGAMCLLHASL

SIGMAR1

86

Q99720
AWCGSVRSMAMGSHS

STARD9

2406

Q9P2P6
MWRAGSMSAELGVGC

PLPBP

1

O94903
TMGMWSIGAGALGAA

PRXL2A

11

Q9BRX8
GMKRFCDDIAWMTGR

SLC6A18

496

Q96N87
EGTTLAMTNGAWVMG

APOL5

281

Q9BWW9
AMTNGAWVMGAAGAG

APOL5

286

Q9BWW9
TWRTNMTGMAGLAGL

CLEC17A

211

Q6ZS10
MDLRAGDSWGMLACL

CLCF1

1

Q9UBD9
MAACIAAGHWAAMGL

MRPL19

1

P49406
LCIGTSSGTMACWDM

PIK3R4

1156

Q99570
LDSLVGGMWTAMDIC

XYLT1

906

Q86Y38
GGMWTAMDICATGPT

XYLT1

911

Q86Y38
AEMTWGGLSTRSEMC

MOXD1

451

Q6UVY6
MLFRMEWGCALTGSQ

PGF

161

P49763
LCKLCGSGMWDSGSM

TBC1D16

706

Q8TBP0
SMGDCTGWLEDFLMG

RAET1G

186

Q6H3X3
SMGDCIGWLEDFLMG

RAET1L

186

Q5VY80
WGFNSSLACIAMGGM

SLC14A1

286

Q13336
WCGMTAKMGTVLSGV

TMEM217

6

Q8N7C4
SMGDCIGWLEDFLMG

ULBP2

186

Q9BZM5
VWQMDTGALDRCVMG

WDR7

586

Q9Y4E6