Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein antigen binding	SIRPB1 SIRPA	3.33e-04	16	34	2	GO:1990405
GeneOntologyMolecularFunction	protein binding involved in heterotypic cell-cell adhesion	SIRPB1 SIRPA	4.23e-04	18	34	2	GO:0086080
GeneOntologyBiologicalProcess	negative regulation of I-kappaB phosphorylation	SIRPB1 SIRPA	1.58e-05	4	34	2	GO:1903720
GeneOntologyBiologicalProcess	negative regulation of macrophage inflammatory protein 1 alpha production	SIRPB1 SIRPA	2.63e-05	5	34	2	GO:0071641
GeneOntologyBiologicalProcess	negative regulation of JNK cascade	NCOR1 SIRPB1 SIRPA	4.83e-05	43	34	3	GO:0046329
GeneOntologyBiologicalProcess	regulation of macrophage inflammatory protein 1 alpha production	SIRPB1 SIRPA	7.34e-05	8	34	2	GO:0071640
GeneOntologyBiologicalProcess	negative regulation of chemokine (C-C motif) ligand 5 production	SIRPB1 SIRPA	9.43e-05	9	34	2	GO:0071650
GeneOntologyBiologicalProcess	macrophage inflammatory protein-1 alpha production	SIRPB1 SIRPA	9.43e-05	9	34	2	GO:0071608
GeneOntologyBiologicalProcess	regulation of I-kappaB phosphorylation	SIRPB1 SIRPA	1.18e-04	10	34	2	GO:1903719
GeneOntologyBiologicalProcess	cellular response to interleukin-12	SIRPB1 SIRPA	2.03e-04	13	34	2	GO:0071349
GeneOntologyBiologicalProcess	monocyte extravasation	SIRPB1 SIRPA	2.03e-04	13	34	2	GO:0035696
GeneOntologyBiologicalProcess	regulation of chemokine (C-C motif) ligand 5 production	SIRPB1 SIRPA	2.73e-04	15	34	2	GO:0071649
GeneOntologyBiologicalProcess	chemokine (C-C motif) ligand 5 production	SIRPB1 SIRPA	3.12e-04	16	34	2	GO:0071609
GeneOntologyBiologicalProcess	response to interleukin-12	SIRPB1 SIRPA	3.12e-04	16	34	2	GO:0070671
GeneOntologyBiologicalProcess	negative regulation of interferon-beta production	SIRPB1 SIRPA	4.92e-04	20	34	2	GO:0032688
GeneOntologyBiologicalProcess	positive regulation of phagocytosis	SIRPB1 SIRPA IL2RB	5.76e-04	99	34	3	GO:0050766
GeneOntologyBiologicalProcess	I-kappaB phosphorylation	SIRPB1 SIRPA	5.97e-04	22	34	2	GO:0007252
GeneOntologyBiologicalProcess	response to reactive oxygen species	KPNA4 SESN2 SIRPB1 SIRPA	6.91e-04	246	34	4	GO:0000302
GeneOntologyBiologicalProcess	negative regulation of nitric oxide metabolic process	SIRPB1 SIRPA	7.73e-04	25	34	2	GO:1904406
GeneOntologyBiologicalProcess	negative regulation of nitric oxide biosynthetic process	SIRPB1 SIRPA	7.73e-04	25	34	2	GO:0045019
Domain	EamA_dom	SLC35G5 SLC35G6 SLC35G3	2.16e-06	14	35	3	IPR000620
Domain	EamA	SLC35G5 SLC35G6 SLC35G3	2.16e-06	14	35	3	PF00892
Domain	ARM-type_fold	KPNA4 HSF2BP FRYL RSPH14 NUP188 DOCK9	3.56e-05	339	35	6	IPR016024
Domain	-	KPNA4 HSF2BP FRYL RSPH14	7.62e-04	222	35	4	1.25.10.10
Domain	Transl_B-barrel	MRPL3 GSPT2	1.16e-03	27	35	2	IPR009000
Domain	Arm	KPNA4 RSPH14	1.53e-03	31	35	2	PF00514
Domain	ARM-like	KPNA4 HSF2BP FRYL RSPH14	1.57e-03	270	35	4	IPR011989
Domain	Armadillo	KPNA4 RSPH14	3.50e-03	47	35	2	IPR000225
Domain	RabGAP-TBC	TBC1D28 TBC1D26	4.43e-03	53	35	2	PF00566
Domain	C1-set	SIRPB1 SIRPA	4.59e-03	54	35	2	PF07654
Domain	TBC_RABGAP	TBC1D28 TBC1D26	4.76e-03	55	35	2	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D28 TBC1D26	4.76e-03	55	35	2	IPR000195
Domain	IGc1	SIRPB1 SIRPA	4.93e-03	56	35	2	SM00407
Domain	Ig_C1-set	SIRPB1 SIRPA	5.28e-03	58	35	2	IPR003597
Domain	IGv	SIRPB1 SIRPA	8.69e-03	75	35	2	SM00406
Pubmed	RT-PCR of fatty acid elongases.	SLC35G5 SLC35G6 SLC35G3	4.07e-09	4	36	3	9056918
Pubmed	Emergence of primate genes by retrotransposon-mediated sequence transduction.	SLC35G5 SLC35G6 SLC35G3	4.07e-09	4	36	3	17101974
Pubmed	ER stress transforms random olfactory receptor choice into axon targeting precision.	OR8A1 OR10J5 OR4E1	8.52e-08	9	36	3	36167070
Pubmed	Minigenes impart odorant receptor-specific axon guidance in the olfactory bulb.	OR8A1 OR10J5	1.04e-06	2	36	2	12194868
Pubmed	Spontaneous and sensory-evoked activity in mouse olfactory sensory neurons with defined odorant receptors.	OR8A1 OR10J5	1.04e-06	2	36	2	23596334
Pubmed	SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis.	SIRPB1 SIRPA	3.12e-06	3	36	2	36202053
Pubmed	Requirement of SIRPα for protective immunity against Leishmania major.	SIRPB1 SIRPA	3.12e-06	3	36	2	20854790
Pubmed	Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance.	SIRPB1 SIRPA	3.12e-06	3	36	2	33074246
Pubmed	Central nervous system antigen P84 can serve as a substrate for neurite outgrowth.	SIRPB1 SIRPA	3.12e-06	3	36	2	2303162
Pubmed	SHPS-1 promotes the survival of circulating erythrocytes through inhibition of phagocytosis by splenic macrophages.	SIRPB1 SIRPA	3.12e-06	3	36	2	16141346
Pubmed	Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the migration of Langerhans cells from the epidermis to draining lymph nodes.	SIRPB1 SIRPA	3.12e-06	3	36	2	15034021
Pubmed	Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury.	SIRPB1 SIRPA	3.12e-06	3	36	2	31883525
Pubmed	Signal regulatory protein α is associated with tumor-polarized macrophages phenotype switch and plays a pivotal role in tumor progression.	SIRPB1 SIRPA	3.12e-06	3	36	2	23504854
Pubmed	Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 mutant mice.	SIRPB1 SIRPA	3.12e-06	3	36	2	17617577
Pubmed	Resistance to collagen-induced arthritis in SHPS-1 mutant mice.	SIRPB1 SIRPA	3.12e-06	3	36	2	18455510
Pubmed	Regulation of Phagocyte Migration by Signal Regulatory Protein-Alpha Signaling.	SIRPB1 SIRPA	3.12e-06	3	36	2	26057870
Pubmed	Non-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and Spleen.	SIRPB1 SIRPA	3.12e-06	3	36	2	26222253
Pubmed	Essential roles of SHPS-1 in induction of contact hypersensitivity of skin.	SIRPB1 SIRPA	3.12e-06	3	36	2	18809435
Pubmed	SIRPα signaling regulates podocyte structure and function.	SIRPB1 SIRPA	3.12e-06	3	36	2	23842779
Pubmed	Essential roles of SIRPα in homeostatic regulation of skin dendritic cells.	SIRPB1 SIRPA	3.12e-06	3	36	2	20955735
Pubmed	A role for SHPS-1/SIRPalpha in Concanavalin A-dependent production of MMP-9.	SIRPB1 SIRPA	3.12e-06	3	36	2	17825046
Pubmed	Signal regulatory protein alpha (SIRPalpha)/CD47 interaction and function.	SIRPB1 SIRPA	3.12e-06	3	36	2	19223164
Pubmed	SIRPα deficiency accelerates the pathologic process in models of Parkinson disease.	SIRPB1 SIRPA	3.12e-06	3	36	2	31322787
Pubmed	Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages.	SIRPB1 SIRPA	3.12e-06	3	36	2	18233962
Pubmed	BIT, an immune antigen receptor-like molecule in the brain.	SIRPB1 SIRPA	3.12e-06	3	36	2	9271230
Pubmed	Soluble SIRP-Alpha Promotes Murine Acute Lung Injury Through Suppressing Macrophage Phagocytosis.	SIRPB1 SIRPA	3.12e-06	3	36	2	35634325
Pubmed	Gene structure of mouse BIT/SHPS-1.	SIRPB1 SIRPA	3.12e-06	3	36	2	10585853
Pubmed	Suppression of SHP-1 promotes corticospinal tract sprouting and functional recovery after brain injury.	SIRPB1 SIRPA	3.12e-06	3	36	2	23559001
Pubmed	Negative regulation of platelet clearance and of the macrophage phagocytic response by the transmembrane glycoprotein SHPS-1.	SIRPB1 SIRPA	3.12e-06	3	36	2	12167615
Pubmed	Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk.	SIRPB1 SIRPA	3.12e-06	3	36	2	31507080
Pubmed	The Rho kinase pathway regulates the migration of dendritic cells through SIRP-α.	SIRPB1 SIRPA	3.12e-06	3	36	2	22391241
Pubmed	The murine P84 neural adhesion molecule is SHPS-1, a member of the phosphatase-binding protein family.	SIRPB1 SIRPA	3.12e-06	3	36	2	9348339
Pubmed	Targeting SIRP-α protects from type 2-driven allergic airway inflammation.	SIRPB1 SIRPA	3.12e-06	3	36	2	21108471
Pubmed	Mutational analysis of the mechanism of negative regulation by SRC homology 2 domain-containing protein tyrosine phosphatase substrate-1 of phagocytosis in macrophages.	SIRPB1 SIRPA	3.12e-06	3	36	2	16920950
Pubmed	Src homology 2 domain-containing protein tyrosine phosphatase substrate 1 regulates the induction of Langerhans cell maturation.	SIRPB1 SIRPA	3.12e-06	3	36	2	17109464
Pubmed	SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress.	SIRPB1 SIRPA	3.12e-06	3	36	2	22671569
Pubmed	Signal regulatory protein α negatively regulates mast-cell activation following FcεRI aggregation.	SIRPB1 SIRPA	3.12e-06	3	36	2	23504624
Pubmed	Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRPα inhibitory signaling in mice.	SIRPB1 SIRPA	3.12e-06	3	36	2	23472187
Pubmed	Involvement of signal regulatory protein α, a negative regulator of Toll-like receptor signaling, in impairing the MyD88-independent pathway and intracellular killing of Burkholderia pseudomallei-infected mouse macrophages.	SIRPB1 SIRPA	3.12e-06	3	36	2	22988019
Pubmed	Hypothermia-induced tyrosine phosphorylation of SIRPα in the brain.	SIRPB1 SIRPA	3.12e-06	3	36	2	22468987
Pubmed	Endothelial SIRPα signaling controls VE-cadherin endocytosis for thymic homing of progenitor cells.	SIRPB1 SIRPA	3.12e-06	3	36	2	35511221
Pubmed	Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha.	SIRPB1 SIRPA	3.12e-06	3	36	2	34917090
Pubmed	Effect of Serum Deprivation Stress on Signal Induction Regulatory Protein-Alpha (SIRP-Alpha)-Mediated Erythrophagocytosis by Macrophages.	SIRPB1 SIRPA	3.12e-06	3	36	2	30894504
Pubmed	Regulation by Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 of alpha-galactosylceramide-induced antimetastatic activity and Th1 and Th2 responses of NKT cells.	SIRPB1 SIRPA	3.12e-06	3	36	2	17475843
Pubmed	Inhibitory regulation of osteoclast bone resorption by signal regulatory protein alpha.	SIRPB1 SIRPA	3.12e-06	3	36	2	19667119
Pubmed	Expression of Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 in pancreatic beta-Cells and its role in promotion of insulin secretion and protection against diabetes.	SIRPB1 SIRPA	3.12e-06	3	36	2	18635660
Pubmed	SIRP/CD47 signaling in neurological disorders.	SIRPB1 SIRPA	3.12e-06	3	36	2	25795378
Pubmed	SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors.	SIRPB1 SIRPA	3.12e-06	3	36	2	28669759
Pubmed	Tyrosine phosphorylation of the transmembrane protein SIRPα: Sensing synaptic activity and regulating ectodomain cleavage for synapse maturation.	SIRPB1 SIRPA	3.12e-06	3	36	2	29914984
Pubmed	Focal cerebral ischemia upregulates SHP-1 in reactive astrocytes in juvenile mice.	SIRPB1 SIRPA	3.12e-06	3	36	2	12742627
Pubmed	Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103(+) CD11b(+) DCs in the intestinal lamina propria.	SIRPB1 SIRPA	3.12e-06	3	36	2	25236797
Pubmed	SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility.	SIRPB1 SIRPA	3.12e-06	3	36	2	11118207
Pubmed	Dendritic cell SIRPα regulates homeostasis of dendritic cells in lymphoid organs.	SIRPB1 SIRPA	3.12e-06	3	36	2	25818708
Pubmed	SIRPα controls the activity of the phagocyte NADPH oxidase by restricting the expression of gp91(phox).	SIRPB1 SIRPA	3.12e-06	3	36	2	23022485
Pubmed	Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity.	SIRPB1 SIRPA	3.12e-06	3	36	2	29158380
Pubmed	Deficiency in SIRP-α cytoplasmic recruitment confers protection from acute kidney injury.	SIRPB1 SIRPA	3.12e-06	3	36	2	31370677
Pubmed	Intratumoral SIRPα-deficient macrophages activate tumor antigen-specific cytotoxic T cells under radiotherapy.	SIRPB1 SIRPA	3.12e-06	3	36	2	34050181
Pubmed	Lack of non-hematopoietic SIRPα signaling disturbs the splenic marginal zone architecture resulting in accumulation and displacement of marginal zone B cells.	SIRPB1 SIRPA	3.12e-06	3	36	2	25817792
Pubmed	Ectodomain shedding of SHPS-1 and its role in regulation of cell migration.	SIRPB1 SIRPA	3.12e-06	3	36	2	15123722
Pubmed	A functional subset of CD8+ T cells during chronic exhaustion is defined by SIRPα expression.	SIRPB1 SIRPA	3.12e-06	3	36	2	30770827
Pubmed	Signal regulatory protein α protects podocytes through promoting autophagic activity.	SIRPB1 SIRPA	3.12e-06	3	36	2	30888336
Pubmed	Critical role for protein tyrosine phosphatase SHP-1 in controlling infection of central nervous system glia and demyelination by Theiler's murine encephalomyelitis virus.	SIRPB1 SIRPA	3.12e-06	3	36	2	12134038
Pubmed	Podocyte SIRPα reduction aggravates lupus nephritis via promoting T cell inflammatory responses.	SIRPB1 SIRPA	3.12e-06	3	36	2	38758648
Pubmed	SIRPα+ dendritic cells promote the development of fibroblastic reticular cells in murine peripheral lymph nodes.	SIRPB1 SIRPA	3.12e-06	3	36	2	31099900
Pubmed	Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration.	SIRPB1 SIRPA	3.12e-06	3	36	2	33795678
Pubmed	HSF1 promotes the viability of islet β-cells via upregulating SIRPα expression.	SIRPB1 SIRPA	6.24e-06	4	36	2	32141563
Pubmed	CD47 restricts antiviral function of alveolar macrophages during influenza virus infection.	SIRPB1 SIRPA	6.24e-06	4	36	2	36437873
Pubmed	Enhanced phagocytosis of CD47-deficient red blood cells by splenic macrophages requires SHPS-1.	SIRPB1 SIRPA	6.24e-06	4	36	2	16580635
Pubmed	CD47-signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction.	SIRPB1 SIRPA	6.24e-06	4	36	2	22042861
Pubmed	SIRPα Mediates IGF1 Receptor in Cardiomyopathy Induced by Chronic Kidney Disease.	SIRPB1 SIRPA	6.24e-06	4	36	2	35722884
Pubmed	Membrane mobility and clustering of Integrin Associated Protein (IAP, CD47)--major differences between mouse and man and implications for signaling.	SIRPB1 SIRPA	6.24e-06	4	36	2	16697668
Pubmed	SIRPα - CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen.	SIRPB1 SIRPA	6.24e-06	4	36	2	35413056
Pubmed	Dominant negative form of signal-regulatory protein-alpha (SIRPalpha /SHPS-1) inhibits tumor necrosis factor-mediated apoptosis by activation of NF-kappa B.	SIRPB1 SIRPA	6.24e-06	4	36	2	12446684
Pubmed	Synapse maturation by activity-dependent ectodomain shedding of SIRPα.	SIRPB1 SIRPA	6.24e-06	4	36	2	24036914
Pubmed	An essential role for the association of CD47 to SHPS-1 in skeletal remodeling.	SIRPB1 SIRPA	6.24e-06	4	36	2	21638321
Pubmed	Absence of adenylyl cyclase 3 perturbs peripheral olfactory projections in mice.	OR8A1 OR10J5	6.24e-06	4	36	2	17581954
Pubmed	The absence of CD47 promotes nerve fiber growth from cultured ventral mesencephalic dopamine neurons.	SIRPB1 SIRPA	6.24e-06	4	36	2	23049778
Pubmed	Macrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement.	SIRPB1 SIRPA	6.24e-06	4	36	2	22976304
Pubmed	Regulation by SIRPα of dendritic cell homeostasis in lymphoid tissues.	SIRPB1 SIRPA	6.24e-06	4	36	2	20682853
Pubmed	Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein α (SIRPα) signaling.	SIRPB1 SIRPA	6.24e-06	4	36	2	23990469
Pubmed	Signal regulatory protein-α protects against cardiac hypertrophy via the disruption of toll-like receptor 4 signaling.	SIRPB1 SIRPA	6.24e-06	4	36	2	24101669
Pubmed	Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways.	SIRPB1 SIRPA	6.24e-06	4	36	2	34097709
Pubmed	Signal regulatory protein-α interacts with the insulin receptor contributing to muscle wasting in chronic kidney disease.	SIRPB1 SIRPA	6.24e-06	4	36	2	23515050
Pubmed	TLR5 mediates CD172α(+) intestinal lamina propria dendritic cell induction of Th17 cells.	SIRPB1 SIRPA	6.24e-06	4	36	2	26907705
Pubmed	Surfactant protein D prevents mucin overproduction in airway goblet cells via SIRPα.	SIRPB1 SIRPA	6.24e-06	4	36	2	38245585
Pubmed	CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis.	SIRPB1 SIRPA	6.24e-06	4	36	2	32768386
Pubmed	Dual regulation of SIRPalpha phosphorylation by integrins and CD47.	SIRPB1 SIRPA	6.24e-06	4	36	2	17584740
Pubmed	Blocking the CD47-SIRPα interaction reverses the disease phenotype in a polycythemia vera mouse model.	SIRPB1 SIRPA	6.24e-06	4	36	2	37095207
Pubmed	Self inhibition of phagocytosis: the affinity of 'marker of self' CD47 for SIRPalpha dictates potency of inhibition but only at low expression levels.	SIRPB1 SIRPA	6.24e-06	4	36	2	20299253
Pubmed	Protein tyrosine phosphatase Shp2 positively regulates cold stress-induced tyrosine phosphorylation of SIRPα in neurons.	SIRPB1 SIRPA	6.24e-06	4	36	2	34237430
Pubmed	Down-regulation of platelet surface CD47 expression in Escherichia coli O157:H7 infection-induced thrombocytopenia.	SIRPB1 SIRPA	6.24e-06	4	36	2	19771158
Pubmed	Inflammation Unrestrained by SIRPα Induces Secondary Hemophagocytic Lymphohistiocytosis Independent of IFN-γ.	SIRPB1 SIRPA	6.24e-06	4	36	2	33028619
Pubmed	CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development.	SIRPB1 SIRPA	6.24e-06	4	36	2	30308165
Pubmed	Loss of Cell Surface CD47 Clustering Formation and Binding Avidity to SIRPα Facilitate Apoptotic Cell Clearance by Macrophages.	SIRPB1 SIRPA	6.24e-06	4	36	2	26085683
Pubmed	G protein-coupled odorant receptors underlie mechanosensitivity in mammalian olfactory sensory neurons.	OR8A1 OR10J5	6.24e-06	4	36	2	25550517
Pubmed	High expression of inhibitory receptor SHPS-1 and its association with protein-tyrosine phosphatase SHP-1 in macrophages.	SIRPB1 SIRPA	6.24e-06	4	36	2	9712903
Pubmed	The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment.	SIRPB1 SIRPA	6.24e-06	4	36	2	24269920
Pubmed	Prion pathogenesis is unaltered in the absence of SIRPα-mediated "don't-eat-me" signaling.	SIRPB1 SIRPA	6.24e-06	4	36	2	28545141
Pubmed	Activation of protein-tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain molecule.	SIRPB1 SIRPA	6.24e-06	4	36	2	8810330
Pubmed	Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses.	SIRPB1 SIRPA	6.24e-06	4	36	2	10477552
Cytoband	17p11.2	TBC1D28 NCOR1 TBC1D26	2.68e-04	159	36	3	17p11.2
Cytoband	20p13	SIRPB1 SIRPA	2.93e-03	102	36	2	20p13
GeneFamily	CD molecules\|V-set domain containing\|C1-set domain containing\|Signal regulatory proteins	SIRPB1 SIRPA	1.68e-05	5	24	2	747
GeneFamily	C1-set domain containing	SIRPB1 SIRPA	1.41e-03	42	24	2	591
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	SIRPB1 SIRPA IL2RB	1.48e-02	394	24	3	471
GeneFamily	Solute carriers	SLC35G5 SLC35G6 SLC35G3	1.49e-02	395	24	3	752
GeneFamily	Adenosine receptors\|V-set domain containing	SIRPB1 SIRPA	1.96e-02	163	24	2	590
Coexpression	BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS	SLC35G5 CERS2 FRYL SIRPB1 SIRPA SLC35G6 IL2RB SLC35G3	1.21e-05	871	34	8	MM1005
ToppCell	Healthy-B_cell\|World / disease group, cell group and cell class	SLC35G5 SESN2 IL2RB DOCK9	5.78e-06	146	36	4	588359d3df6ad7090b7fa6c7f8d29cc1717e7f4f
Disease	level of tyrosine-protein phosphatase non-receptor type substrate 1 in blood serum	SIRPB1 SIRPA	1.37e-06	2	35	2	OBA_2040362
Disease	signal-regulatory protein beta-1 measurement	SIRPB1 SIRPA	4.89e-05	9	35	2	EFO_0802069
Disease	immature platelet count	SIRPB1 SIRPA	7.04e-03	106	35	2	EFO_0803544
Disease	eosinophil measurement	SESN2 CTNS	7.30e-03	108	35	2	EFO_0803540
Disease	peptide measurement	DLEC1 IL2RB	7.43e-03	109	35	2	EFO_0010520
Disease	immature platelet fraction	SIRPB1 SIRPA	8.10e-03	114	35	2	EFO_0009187
Disease	creatinine measurement, glomerular filtration rate	CERS2 PHTF2	8.52e-03	117	35	2	EFO_0004518, EFO_0005208
Disease	immature platelet measurement	SIRPB1 SIRPA	8.80e-03	119	35	2	EFO_0803541

Protein segments in the cluster

Peptide	Gene	Start	Entry
CVVVLLSAELVQHFH	PIK3AP1	66	Q6ZUJ8
FKEQIIHHVATIILI	CERS2	206	Q96G23
KIVRCHEHIEILTVN	MCTS1	51	Q9ULC4
RLLQECLTLHHLVVE	NUDT18	236	Q6ZVK8
EHLLHVTVVLCVVLL	LRIT2	461	A6NDA9
IHEAVKAIVLCHNVT	ATP9B	541	O43861
AVLHIHTCIEEVEIT	GSPT2	541	Q8IYD1
CNIAVILLTDLIIDH	FRYL	1596	O94915
VIAHRVTTVLNCDHI	ABCC11	1331	Q96J66
VTRVIIHVVAQCHEE	DOCK9	891	Q9BZ29
ISLQVVHVETHRCNI	IL2RB	136	P14784
HAVVLTLIIIVQCCL	CTNS	211	O60931
ITLEALHCQHLETVL	DLEC1	931	Q9Y238
CTILTVVIIIAAQHH	PRRT1	286	Q99946
IIMSHHTCLLLVAVV	OR8A1	151	Q8NGG7
ANIIIVTIICIDHHL	OR10J5	41	Q8NHC4
LLIIAVITLDQHLHT	OR14I1	41	A6ND48
KHVVTLLQVQDCHVL	MRPL3	116	P09001
VCLHVLRLVQSVVLE	HSF2BP	271	O75031
LVCAVLHSEVVVALI	SLC35G5	281	Q96KT7
LAELIQALVLLTHCH	SESN2	191	P58004
VVFICCAQLLHVHEI	PHTF2	646	Q8N3S3
LVCAVLHSEVVVALI	SLC35G3	281	Q8N808
HRLITLADHICQIIT	NCOR1	2046	O75376
DVHSQVICEVAHVTL	SIRPA	221	P78324
IIHCIQLDVSHTLQK	TBC1D26	141	Q86UD7
DCEHVIVITDIRLVH	SNAPC3	316	Q92966
VHSQVICEVAHVTLQ	SIRPB1	221	Q5TFQ8
VDAVRIVHIHSVIIL	BRCC3	66	P46736
VHSQVICEIAHITLQ	SIRPB1	221	O00241
LACIDTHVIEILIVS	OR4E1	191	P0C645
QVCHFDVIPILVHLL	RSPH14	226	Q9UHP6
IVVTHCLLNPHALVI	ZBED8	266	Q8IZ13
ILELIHAILNLCHET	NUP188	736	Q5SRE5
LVCAVLHSEVVVALI	SLC35G6	281	P0C7Q6
IIHCIQLDVSHTLQK	TBC1D28	141	Q2M2D7
FIHITEQLSTHICVV	PP6455	86	Q8WZ26
ALCVLIHHTDVNILV	KPNA4	246	O00629
LLLCHALAIAVVQIV	LYPD6B	16	Q8NI32