Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	-	LRP8 TENM3 TRIM56 HHIPL2	8.28e-05	39	111	4	2.120.10.30
Domain	2oxoglutarate_DH_E1	OGDH DHTKD1	1.05e-04	3	111	2	IPR011603
Domain	KGD_C	OGDH DHTKD1	1.05e-04	3	111	2	IPR031717
Domain	SBF2	SBF1 SBF2	1.05e-04	3	111	2	PF12335
Domain	OxoGdeHyase_C	OGDH DHTKD1	1.05e-04	3	111	2	PF16870
Domain	SBF1/SBF2	SBF1 SBF2	1.05e-04	3	111	2	IPR022096
Domain	6-blade_b-propeller_TolB-like	LRP8 TENM3 TRIM56 HHIPL2	1.59e-04	46	111	4	IPR011042
Domain	TF_AP2	TFAP2D TFAP2B	3.46e-04	5	111	2	IPR004979
Domain	TF_AP2_C	TFAP2D TFAP2B	3.46e-04	5	111	2	IPR013854
Domain	TF_AP-2	TFAP2D TFAP2B	3.46e-04	5	111	2	PF03299
Domain	E1_dh	OGDH DHTKD1	5.17e-04	6	111	2	PF00676
Domain	DH_E1	OGDH DHTKD1	5.17e-04	6	111	2	IPR001017
Domain	Transketolase-like_Pyr-bd	OGDH DHTKD1	9.57e-04	8	111	2	IPR005475
Domain	Transket_pyr	OGDH DHTKD1	9.57e-04	8	111	2	SM00861
Domain	Transket_pyr	OGDH DHTKD1	9.57e-04	8	111	2	PF02779
Domain	Tyr_kinase_rcpt_2_CS	INSRR ALK	1.86e-03	11	111	2	IPR002011
Domain	WD40_repeat_dom	FBXW9 NBEA LRRK1 SF3B3 TENM3 CSTF1 WDR90	1.99e-03	297	111	7	IPR017986
Domain	Quinoprot_gluc/sorb_DH	TRIM56 HHIPL2	2.22e-03	12	111	2	IPR011041
Domain	RECEPTOR_TYR_KIN_II	INSRR ALK	2.22e-03	12	111	2	PS00239
Domain	Olfact_rcpt	OR2M4 OR52R1 OR4P4 OR51I2 OR52E6 OR8B12 OR6T1 OR9A2	2.40e-03	393	111	8	IPR000725
Domain	THDP-binding	OGDH DHTKD1	2.62e-03	13	111	2	IPR029061
Domain	-	OGDH DHTKD1	2.62e-03	13	111	2	3.40.50.970
Domain	Myotubularin-like_Pase_dom	SBF1 SBF2	3.04e-03	14	111	2	IPR010569
Domain	uDENN	SBF1 SBF2	3.04e-03	14	111	2	SM00800
Domain	PPASE_MYOTUBULARIN	SBF1 SBF2	3.04e-03	14	111	2	PS51339
Domain	Myotubularin_fam	SBF1 SBF2	3.04e-03	14	111	2	IPR030564
Domain	Myotub-related	SBF1 SBF2	3.04e-03	14	111	2	PF06602
Domain	uDENN	SBF1 SBF2	3.49e-03	15	111	2	PF03456
Domain	GRAM	SBF1 SBF2	3.98e-03	16	111	2	SM00568
Domain	DENN	SBF1 SBF2	3.98e-03	16	111	2	SM00799
Domain	DENN	SBF1 SBF2	3.98e-03	16	111	2	PF02141
Domain	dDENN	SBF1 SBF2	3.98e-03	16	111	2	PF03455
Domain	UDENN	SBF1 SBF2	3.98e-03	16	111	2	PS50946
Domain	DDENN	SBF1 SBF2	3.98e-03	16	111	2	PS50947
Domain	dDENN	SBF1 SBF2	3.98e-03	16	111	2	SM00801
Domain	dDENN_dom	SBF1 SBF2	3.98e-03	16	111	2	IPR005112
Domain	uDENN_dom	SBF1 SBF2	3.98e-03	16	111	2	IPR005113
Domain	DENN	SBF1 SBF2	3.98e-03	16	111	2	PS50211
Domain	DENN_dom	SBF1 SBF2	3.98e-03	16	111	2	IPR001194
Domain	CarboxyPept-like_regulatory	TENM3 NOMO2	4.49e-03	17	111	2	IPR008969
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABCC3 ZBTB4 FBRS C15orf39 LRRK1 PPP1R26 INTS5 SBF1 CANT1 KLHL36 SSU72 SBF2 MCM3AP NAV1 NLRC5 WDR90 RAI1	1.09e-07	1105	113	17	35748872
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SDK2 DLGAP5 LRRK1 INTS5 SF3B3 SBF1 DDHD1 WDR90 FLRT3 IGSF1 CARNS1 RAI1	1.66e-07	529	113	12	14621295
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	PPP1R26 MCM3AP NAV1 MACF1 IGSF1 CARNS1 PLXNA2	2.41e-07	130	113	7	12421765
Pubmed	Synthetic analogues of 2-oxo acids discriminate metabolic contribution of the 2-oxoglutarate and 2-oxoadipate dehydrogenases in mammalian cells and tissues.	OGDH DHTKD1	1.05e-05	2	113	2	32024885
Pubmed	A human specific Alu DNA cassette is found flanking the genes of transcription factor AP2.	TFAP2D TFAP2B	1.05e-05	2	113	2	30975199
Pubmed	Angiotensin II-induced Hypertension is Reduced by Deficiency of P-selectin Glycoprotein Ligand-1.	SELPLG AGT	1.05e-05	2	113	2	29459637
Pubmed	Distinct roles for the Charcot-Marie-Tooth disease-causing endosomal regulators Mtmr5 and Mtmr13 in axon radial sorting and Schwann cell myelination.	SBF1 SBF2	1.05e-05	2	113	2	34718573
Pubmed	Pals-associated tight junction protein functionally links dopamine and angiotensin II to the regulation of sodium transport in renal epithelial cells.	AGT PATJ	1.05e-05	2	113	2	19563532
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	FBRS C15orf39 CCDC6 SF3B3 NOMO2 MCM3AP NAV1 MACF1 CRYBG3 PATJ	2.31e-05	588	113	10	38580884
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	UBR2 ENC1 RNF213 PARD3B ATP8B1 H6PD OGDH LRP8 PXDN SBF2 NAV1 NLRC5 MACF1 PATJ CLEC16A RAI1	2.59e-05	1489	113	16	28611215
Pubmed	Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor.	RNF213 ALK	3.13e-05	3	113	2	12112524
Pubmed	DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo.	OGDH DHTKD1	3.13e-05	3	113	2	32160276
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBR2 PXDN TENM3 MCM3AP NAV1 MACF1 CLEC16A PLXNA2	5.76e-05	407	113	8	12693553
Pubmed	Immunocytochemical localization of peroxisomal proteins in human liver and kidney.	EHHADH AGXT	6.25e-05	4	113	2	9053548
Pubmed	The role of Sp1 and AP-2 in basal and protein kinase A--induced expression of mitochondrial serine:pyruvate aminotransferase in hepatocytes.	TFAP2B AGXT	6.25e-05	4	113	2	12169688
Pubmed	Expression of Tfap2d, the gene encoding the transcription factor Ap-2 delta, during mouse embryogenesis.	TFAP2D TFAP2B	6.25e-05	4	113	2	12711551
Pubmed	Isolation of differentially expressed cDNAs from p53-dependent apoptotic cells: activation of the human homologue of the Drosophila peroxidasin gene.	AIFM2 PXDN	1.04e-04	5	113	2	10441517
Pubmed	Analysis of transcription factor AP-2 expression and function during mouse preimplantation development.	TFAP2D TFAP2B	1.04e-04	5	113	2	16672719
Pubmed	AP-2α and AP-2β regulate dorsal interneuron specification in the spinal cord.	TFAP2D TFAP2B	1.04e-04	5	113	2	27984181
Pubmed	RET, ROS1 and ALK fusions in lung cancer.	CCDC6 ALK	1.04e-04	5	113	2	22327623
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ABCC3 SLC43A1 ROR1 LRP8 CANT1 NAV1 FLRT3 PATJ PLXNA2	1.04e-04	569	113	9	30639242
Pubmed	Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening.	ENC1 TFAP2B PLXNA2	1.55e-04	32	113	3	16516881
Pubmed	Transcription factor gene AP-2 gamma essential for early murine development.	TFAP2D TFAP2B	1.56e-04	6	113	2	11940672
Pubmed	PlexinA2 and Sema6A are required for retinal progenitor cell migration.	TFAP2B PLXNA2	1.56e-04	6	113	2	27301906
Pubmed	Loss of AP-2delta reduces retinal ganglion cell numbers and axonal projections to the superior colliculus.	TFAP2D TFAP2B	1.56e-04	6	113	2	27259519
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	SPNS1 ROR1 RNF213 ATP8B1 OGDH LRP8 INTS5 COG1 CANT1 MCM3AP MACF1 FLRT3	1.79e-04	1061	113	12	33845483
Pubmed	Genome-wide association study of smoking behaviours among Bangladeshi adults.	UBR2 TENM3 SBF2	1.86e-04	34	113	3	24665060
Pubmed	Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.	BRIP1 USP9Y SBF1 SBF2	1.91e-04	87	113	4	17148452
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SPNS1 USP9Y OGDH INTS5 SF3B3 SBF1 SACS CSTF1 AGK MACF1 MED17 TNXB	2.14e-04	1082	113	12	38697112
Pubmed	Cloning and characterization of the mouse AP-2 epsilon gene: a novel family member expressed in the developing olfactory bulb.	TFAP2D TFAP2B	2.17e-04	7	113	2	14572467
Pubmed	AP-2ε Expression in Developing Retina: Contributing to the Molecular Diversity of Amacrine Cells.	TFAP2D TFAP2B	2.17e-04	7	113	2	29467543
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	SDK2 LRP8 TENM3 PLXNA2	2.27e-04	91	113	4	28558017
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	THNSL1 C15orf39 AIFM2 TMEM62 SBF1 DDHD1 CRYBG3 PATJ CLEC16A	2.80e-04	650	113	9	38777146
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	TFAP2D C15orf39 MCM3AP PATJ RAI1	3.14e-04	180	113	5	35198878
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	ROR1 INSRR LRP8 ALK	3.38e-04	101	113	4	23382219
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SDK2 ZBTB4 TENM3 FLRT3	3.65e-04	103	113	4	10819331
Pubmed	Yeast two-hybrid screening of proteins interacting with plasmin receptor subunit: C-terminal fragment of annexin A2.	ZBTB4 OGDH	3.71e-04	9	113	2	21963895
Pubmed	A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities.	MLYCD EHHADH AGXT	4.01e-04	44	113	3	20178365
Pubmed	Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.	SBF1 SBF2	4.63e-04	10	113	2	9736772
Pubmed	Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.	TENM3 FLRT3	4.63e-04	10	113	2	38713721
Pubmed	Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.	GRIA2 NOMO2 SBF2 CLEC16A	4.68e-04	110	113	4	27889896
Pubmed	Charcot-Marie-Tooth Hereditary Neuropathy Overview	SBF1 SBF2 MCM3AP	5.19e-04	48	113	3	20301532
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	UBR2 ABCC3 RNF213 OGFOD3 H6PD LRP8 PXDN TENM3 CANT1 NOMO2 TMEM245 AGT	5.45e-04	1201	113	12	35696571
Pubmed	Charcot-Marie-Tooth Neuropathy Type 4 – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	SBF1 SBF2	5.65e-04	11	113	2	20301641
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	ABCC3 PARD3B TTPAL LRP8 TENM3 NOMO2 NAV1 MACF1 FLRT3	5.80e-04	719	113	9	35337019
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	SDK2 FLRT3 PLXNA2	6.57e-04	52	113	3	26633812
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	CCDC28B PXDN SBF1 SACS NAV1 MACF1	7.76e-04	332	113	6	37433992
Pubmed	Protocadherins.	PCDHB5 PCDHB4	7.97e-04	13	113	2	12231349
Pubmed	Conditional deletion of activating protein 2alpha (AP-2alpha) in the developing retina demonstrates non-cell-autonomous roles for AP-2alpha in optic cup development.	TFAP2D TFAP2B	7.97e-04	13	113	2	17724084
Pubmed	Risk alleles for multiple sclerosis in multiplex families.	CLEC16A ALK	7.97e-04	13	113	2	19506219
Pubmed	Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis.	CLEC16A ALK	9.28e-04	14	113	2	19834503
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ABCC3 DLGAP5 FBRS NBEA DDHD1 AGK MED17 RAI1	1.16e-03	638	113	8	31182584
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZBTB4 RNF213 PPP1R26 SACS SBF2 MACF1 DHTKD1	1.17e-03	493	113	7	15368895
Pubmed	Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system.	PCDHB5 PCDHB4	1.38e-03	17	113	2	18279309
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	ENC1 INSRR SF3B3 KLHL36 TRIM56 ALK	1.39e-03	372	113	6	22939624
Pubmed	Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios.	H6PD TENM3	1.73e-03	19	113	2	14671302
Pubmed	Understanding the development of oral epithelial organs through single cell transcriptomic analysis.	ENC1 GRIA2 TFAP2B	1.76e-03	73	113	3	35831953
Pubmed	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.	PCDHB5 PCDHB4	1.91e-03	20	113	2	11322959
Pubmed	Aerobic glycolysis tunes YAP/TAZ transcriptional activity.	OGDH SF3B3 CSTF1 PATJ	1.97e-03	162	113	4	25796446
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	RNF213 SACS MACF1	1.98e-03	76	113	3	27542412
Pubmed	The human olfactory receptor gene family.	OR2M4 OR52R1 OR51I2 OR52E6 OR8B12 OR6T1 OR9A2	1.98e-03	541	113	7	14983052
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	MAT2A PSMA6 SF3B3 AGK MACF1 CRYBG3 PATJ MED17	2.23e-03	708	113	8	39231216
Pubmed	Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.	GRIA2 LRP8 TENM3	2.45e-03	82	113	3	31073041
Pubmed	The protein tyrosine kinase family of the human genome.	ROR1 INSRR ALK	2.54e-03	83	113	3	11114734
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	ROR1 INSRR LRRK1 LRP8 SBF1 ALK	2.55e-03	420	113	6	28065597
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CYP2A13 PSMA6 GRIA2 OGFOD3 OGDH SF3B3 PXDN SACS COG1 MACF1 PLXNA2 RAI1	2.57e-03	1442	113	12	35575683
Pubmed	Nsp2 has the potential to be a drug target revealed by global identification of SARS-CoV-2 Nsp2-interacting proteins.	THNSL1 PSMA6 AGK	2.63e-03	84	113	3	34159380
Pubmed	Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.	UBR2 FBXW9 RNF213	2.72e-03	85	113	3	19028597
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	BRIP1 SLC43A1 DLGAP5 RNF213 NOMO2 DDHD1 NAV1 PATJ	2.76e-03	733	113	8	34672954
Pubmed	AP-2δ is a crucial transcriptional regulator of the posterior midbrain.	TFAP2D TFAP2B	2.99e-03	25	113	2	21858141
Pubmed	AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex.	TFAP2D TFAP2B	3.23e-03	26	113	2	19749747
Cytoband	1p32-p31	ROR1 MACF1	2.14e-04	9	113	2	1p32-p31
Cytoband	11q14	CAPN5 MED17	3.90e-04	12	113	2	11q14
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	ROR1 INSRR ALK	4.75e-04	40	69	3	321
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	SBF1 SBF2	1.46e-03	15	69	2	903
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THNSL1 FBXW9 PSTPIP1 NEMP2 INTS5 SF3B3	4.06e-06	165	113	6	1d0f60bf47a40ac916f0fcb5532a968742a0edbb
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	MAT2A INSRR GRIA2 NBEA IGSF1 ALK	6.48e-06	179	113	6	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 ATP8B1 H6PD EHHADH AGT DHTKD1	7.35e-06	183	113	6	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	UBR2 BRIP1 RNF213 NOMO2 DDHD1 MACF1	8.06e-06	186	113	6	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NEU4 EHHADH AGT AGXT FLRT3 SLC5A12	1.09e-05	196	113	6	4ebcaac758ed01d918de9c1cd383a84457b615f3
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	UBR2 RNF213 USP9Y DDHD1 NLRC5 MACF1	1.18e-05	199	113	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SLC43A1 ROR1 RIPOR3 TFAP2B TNXB	1.75e-05	126	113	5	f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SLC43A1 ROR1 RIPOR3 TFAP2B TNXB	1.75e-05	126	113	5	fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SLC43A1 ROR1 RIPOR3 TFAP2B TNXB	1.75e-05	126	113	5	3d507f829882d043f633db2612b76936e2042445
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SLC43A1 ROR1 RIPOR3 TFAP2B TNXB	1.75e-05	126	113	5	1ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SLC43A1 ROR1 RIPOR3 TFAP2B TNXB	1.75e-05	126	113	5	2de551d7a8765afec1da8852727c79fec90f45f8
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	SLC43A1 ROR1 RIPOR3 TFAP2B TNXB	4.45e-05	153	113	5	e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	SLC43A1 ROR1 RIPOR3 TFAP2B TNXB	4.45e-05	153	113	5	b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP\|Thalamus / BrainAtlas - Mouse McCarroll V32	SLC43A1 ROR1 RIPOR3 TFAP2B TNXB	4.45e-05	153	113	5	2513edfae62a44e51d3556675a096723194c966c
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG ABCC3 HHIPL2 SLC5A12 TNXB	5.03e-05	157	113	5	7fdc0094dd5729990a91a30c1982a14c74650b52
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG ABCC3 HHIPL2 SLC5A12 TNXB	5.03e-05	157	113	5	c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCell	Control-B_naive-12\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SDK2 FBXW9 NEMP2 CRYBG3 DHTKD1	5.03e-05	157	113	5	4803f601c1ba43260aa09172acc7964aac2c8ccf
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG ABCC3 HHIPL2 SLC5A12 TNXB	5.03e-05	157	113	5	6b5b08bb5520fcf6f4c0560f7ed7645ec179806d
Drug	3-hydroxyoctanoate	MAT2A AIFM2 EHHADH ALK	7.01e-07	15	111	4	CID000026613
Disease	sleep disorder (implicated_via_orthology)	TFAP2D INSRR TFAP2B	6.88e-06	11	104	3	DOID:535 (implicated_via_orthology)
Disease	Primary hyperoxaluria, type I	AGXT AGK	1.23e-05	2	104	2	C0268164
Disease	angiotensinogen measurement	AGT AGXT	7.35e-05	4	104	2	EFO_0008025
Disease	Alzheimer disease, memory impairment	AGT AGXT	7.35e-05	4	104	2	EFO_0001072, MONDO_0004975
Disease	pancreatic carcinoma	BRIP1 ROR1 SBF2 AGT AGXT	3.86e-04	174	104	5	EFO_0002618
Disease	1-ribosyl-imidazoleacetate measurement	CARNS1 DHTKD1	4.36e-04	9	104	2	EFO_0800034
Disease	Charcot-Marie-Tooth disease	SBF1 SBF2 MCM3AP	4.42e-04	42	104	3	cv:C0007959
Disease	Myocardial infarction, susceptibility to	PSMA6 LRP8	9.36e-04	13	104	2	cv:C1832662
Disease	Charcot-Marie-Tooth disease type 4	SBF1 SBF2	9.36e-04	13	104	2	cv:C4082197
Disease	–	PSMA6 LRP8	9.36e-04	13	104	2	608446
Disease	immunoglobulin lambda-like polypeptide 1 measurement	AGT AGXT	1.43e-03	16	104	2	EFO_0801688
Disease	Liver Cirrhosis, Experimental	ISYNA1 ZBTB4 ENC1 NBEA PSTPIP1 PXDN AGT NLRC5 DHTKD1	1.68e-03	774	104	9	C0023893
Disease	neurodegenerative disease (implicated_via_orthology)	UBR2 GRIA2 OGDH CLEC16A	1.76e-03	145	104	4	DOID:1289 (implicated_via_orthology)
Disease	lung cancer	BRIP1 ATP8B1	2.47e-03	21	104	2	MONDO_0008903
Disease	renal system measurement, blood urea nitrogen measurement	TFAP2D TFAP2B	2.71e-03	22	104	2	EFO_0004741, EFO_0004742
Disease	carotid artery disease (is_implicated_in)	SELPLG AGT	2.71e-03	22	104	2	DOID:3407 (is_implicated_in)
Disease	response to radiation, Hematuria	AGT AGXT	2.97e-03	23	104	2	GO_0009314, HP_0000790

Protein segments in the cluster

Peptide	Gene	Start	Entry
EPSGFINLTSFSLHV	TMEM62	461	Q0P6H9
PSSSISGLAGHSVFL	nan	71	A8MUN3
FIPLGETSSLSHTLF	AGK	151	Q53H12
SGPHLTGLELLSFDS	CRYBG3	751	Q68DQ2
FISGVSGSHVFQPIL	APOBEC4	201	Q8WW27
SIFKSNGFFHGISIP	CDKL4	226	Q5MAI5
LKLGHSPAFGSITET	FLRT3	441	Q9NZU0
VSKAVSFHPGGLTFL	CARNS1	26	A5YM72
QIFTSLIIHSLFPGG	AMTN	121	Q6UX39
IPTTFEPGHTGEFLL	CAPN5	471	O15484
ISPGLSYASHTVGFT	CCDC6	366	Q16204
FTLSNLPHFRIGGSV	DHTKD1	346	Q96HY7
GIHVLFPSAFQFTGT	ATP8B1	1121	O43520
PTFTEGSLFFLLHGE	ARMC10	301	Q8N2F6
LSTVVGVFTAPGLHL	AGT	196	P01019
THFSLITHGFGAPAI	TFAP2B	396	Q92481
LTHFSLITHGFGTPA	TFAP2D	376	Q7Z6R9
HGSLPLDSFSKFVAG	RAI1	576	Q7Z5J4
FPGHLVDVSGTGTLS	PCDHB5	731	Q9Y5E4
GGVLKVHPTSTRFTF	ISYNA1	36	Q9NPH2
ISPGYAITIHSGTFT	ABCC3	621	O15438
FSGLLHGSPKTTSLA	PSTPIP1	311	O43586
HVVPFFSSLSGRILG	PARD3B	216	Q8TEW8
IRSFDVGHSFPITGI	FBXW9	381	Q5XUX1
TLGIHLFSSLPFASE	NOMO2	1241	Q5JPE7
FGISASSLHLTKPTF	OGFOD3	196	Q6PK18
ILNHFGTLSFTPDFL	KLHL36	171	Q8N4N3
PTGHSFVLVTSLGLT	MAGEA10	196	P43363
LSSPTPFIIGVHSVF	SBF2	266	Q86WG5
AISFLIETGTLLHFP	LRRK1	896	Q38SD2
GTFLFTSESVGEGHP	MAT2A	16	P31153
VGPFSGLEHTSTFVA	MCM3AP	81	O60318
FPSNHFGTLTGLQSL	SLC43A1	471	O75387
HLGVFSSLSPIPGFT	MLYCD	321	O95822
GAVVPTHGFSSFKFI	CANT1	336	Q8WVQ1
FSAPRTFGLTLGHVV	EHHADH	66	Q08426
TLHVSFITPSFPTDG	GRIA2	106	P42262
SIASGHTPLTITGFN	PLXNA2	1051	O75051
SPTHTFLFSLVLGIF	OR2M4	21	Q96R27
FFLLTGIPGLESSHS	OR51I2	11	Q9H344
DTQFHTSSFLLLGIP	OR52E6	6	Q96RD3
TTHFFGGIEIFILTG	OR4P4	101	Q8NGL7
SKFADFVLGGSHLSP	NEMP2	376	A6NFY4
SAGSLFPHHGTFEVI	MED17	211	Q9NVC6
FPDAGFTGLISFHVT	PADI3	256	Q9ULW8
GTVFLFFIAVLGHTP	NEU4	96	Q8WWR8
GLSDHLPTFLAGLAS	NLRC5	556	Q86WI3
ILEAHLATGGFSLSP	MACF1	1656	Q9UPN3
HTLAGQSSGFTPVFL	SBF1	1471	O95248
GITTATFPILQGHFS	BRIP1	481	Q9BX63
VGFLETISPGYSIHT	GBA	516	P04062
GNSSSHPVSFILLGI	OR52R1	6	Q8NGF1
FPGHLVDVSGTGTLS	PCDHB4	731	Q9Y5E5
VDPFHTLFGIAGLSL	RABGGTB	286	P53611
FHLPTTTFIGGQESA	OGDH	186	Q02218
SSHIIVVSLFFGSGA	OR8B12	241	Q8NGG6
IAGTSVLSPFLHIGS	CEPT1	281	Q9Y6K0
GQELSHPASLFTATG	FBRS	131	Q9HAH7
SPGASAAHFLIISVG	IGSF1	826	Q8N6C5
RGTHGANIDPTFFLS	CYP2A13	161	Q16696
LFSTLETITGQHPAG	COG1	291	Q8WTW3
KVIPGFSDFSLSHTL	DNAH3	3031	Q8TD57
ARHISFGGNLITFSP	DLGAP5	826	Q15398
ASLHSVPGRASTFGI	INSRR	281	P14616
VPITGRSFSLGDLSH	CCDC177	296	Q9NQR7
LFAFGGTSVSHDKLP	ENC1	446	O14682
VGTQTLPHSSSGFLD	DDHD1	796	Q8NEL9
RSISFHPSGDFILVG	CSTF1	221	Q05048
PGLISTHSKFIISFA	HHIPL2	556	Q6UWX4
HLALSGGSSPVALFQ	H6PD	586	O95479
GSAGTPLQHSFLTEV	CCDC28B	71	Q9BUN5
GPVGHLSFSEILDTS	SDK2	896	Q58EX2
SSTGLPVHISGFFGL	SACS	456	Q9NZJ4
LISSTDFLSHPFGIA	LRP8	621	Q14114
LSTLEPGAFHGLQSL	LINGO4	96	Q6UY18
SSATEFHLLGFPGSQ	OR9A2	6	Q8NGT5
SLGLALTHSFGPSLA	NAV1	1386	Q8NEY1
VFSPSSHSFLLILGN	TAS2R13	271	Q9NYV9
GLFIPFSVSSVTHKG	SELPLG	281	Q14242
LFLTHGESSTGVLQP	AGXT	151	P21549
PFSHLILATGSTGPF	AIFM2	101	Q9BRQ8
HLSLETLTAFVLPFG	LTB4R2	181	Q9NPC1
VGFHGTIKSSPSDFI	PUS7L	21	Q9H0K6
FAPFLSRTLLGSHGQ	NBEA	1906	Q8NFP9
GIPTSSVFALHFTEP	SETD3	361	Q86TU7
SFVLLGFPSSHLIQF	OR6T1	11	Q8NGN1
AGFSPLLSTQLFHFG	PPP1R26	1076	Q5T8A7
VVAHIGSSFPGTIIS	INTS5	226	Q6P9B9
GEFHTTTLGTLRKFP	KCTD14	41	Q9BQ13
TSVQGHPILTLFALG	B3GALT9	111	A8MXE2
LFQIFGTGHSSLESP	ALK	216	Q9UM73
AFGPGQTLLSSVHVL	ALKBH7	96	Q9BT30
GLGSSTSTQHLPFRF	CLEC16A	841	Q2KHT3
GHPFGILKADFTIST	CLEC20A	346	Q6ZU45
TSAPGDSLEQHFTGL	C15orf39	756	Q6ZRI6
GVSLSKASHFGPFIA	TTPAL	191	Q9BTX7
TFTALRFPELNGGHS	ROR1	346	Q01973
SAGFDRHITIFSPEG	PSMA6	6	P60900
STLSPGGGVTVFFHA	RNF213	371	Q63HN8
SLSLSPGTHLLAVGF	WDR90	1681	Q96KV7
STSDVGFLPLTFGPH	RIPOR3	421	Q96MK2
HYISSIVSGGPVDTL	PATJ	581	Q8NI35
SLVTLGSSFIPGEHF	SPNS1	136	Q9H2V7
GGITSHQLLGLFPST	TNXB	3981	P22105
TESGKFHISPEGFLT	PXDN	566	Q92626
AFHGISPGLLASEKT	ZBTB4	386	Q9P1Z0
ELFHGPTGSFKDLSL	THNSL1	341	Q8IYQ7
PLESRHFLFKTGTGT	TENM3	246	Q9P273
HFLFKTGTGTTPLFS	TENM3	251	Q9P273
ISFLIGSDSTHVIPG	TENM3	841	Q9P273
SSDFQVHFLKSGGLP	USP9Y	1111	O00507
TLSGGIGILVPFTSH	SF3B3	1121	Q15393
GTFLHPFKSSLTRLG	TMEM245	91	Q9H330
FLTVLIQGSTHAGGF	SLC5A12	196	Q1EHB4
DFSGISLGTGDLHIF	UBR2	1431	Q8IWV8
FSVRSFGTGTHVKLP	SSU72	31	Q9NP77
ALVFLTTSPQGHFVG	TRIM56	636	Q9BRZ2