Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glycogen phosphorylase activity	PYGB PYGM	1.05e-04	3	119	2	GO:0008184
GeneOntologyBiologicalProcess	regulation of GTPase activity	TGM2 EFNA5 ARHGEF10 CCL3 CCL13 GRHL3 CCL23 FGD6 PREX1 AGAP3	2.14e-05	335	117	10	GO:0043087
HumanPheno	Teratoma	MNX1 NSD1 MSH3 STK11	9.32e-07	11	39	4	HP:0009792
Domain	PHOSPHORYLASE	PYGB PYGM	1.18e-04	3	118	2	PS00102
Domain	Glycg_phsphrylas	PYGB PYGM	1.18e-04	3	118	2	IPR011833
Domain	DUF4592	KIAA1210 CRACDL	1.18e-04	3	118	2	IPR028030
Domain	Glyco_trans_35	PYGB PYGM	1.18e-04	3	118	2	IPR000811
Domain	DUF4592	KIAA1210 CRACDL	1.18e-04	3	118	2	PF15262
Domain	Phosphorylase	PYGB PYGM	1.18e-04	3	118	2	PF00343
Domain	EPHD	KDM4C KDM4B RAI1	3.47e-04	22	118	3	PS51805
Domain	PH_dom-like	RANBP2 RASA1 MYO10 IRS1 MTMR4 ARHGEF10 PLCB3 FGD6 PREX1 AGAP3	3.73e-04	426	118	10	IPR011993
Domain	cEGF	LRP1B FBLN1 SCUBE1	5.75e-04	26	118	3	PF12662
Domain	SMALL_CYTOKINES_CC	CCL3 CCL13 CCL23	5.75e-04	26	118	3	PS00472
Domain	cEGF	LRP1B FBLN1 SCUBE1	5.75e-04	26	118	3	IPR026823
Domain	Chemokine_CC_CS	CCL3 CCL13 CCL23	5.75e-04	26	118	3	IPR000827
Domain	GAR	DST GAS2L2	5.84e-04	6	118	2	PS51460
Domain	GAS2	DST GAS2L2	5.84e-04	6	118	2	PF02187
Domain	-	DST GAS2L2	5.84e-04	6	118	2	3.30.920.20
Domain	GAS_dom	DST GAS2L2	5.84e-04	6	118	2	IPR003108
Domain	GAS2	DST GAS2L2	5.84e-04	6	118	2	SM00243
Domain	UmuC	POLH ESCO1	5.84e-04	6	118	2	IPR001126
Domain	-	RANBP2 RASA1 MYO10 IRS1 MTMR4 PLCB3 FGD6 PREX1 AGAP3	8.47e-04	391	118	9	2.30.29.30
Domain	zf-C2H2	HIVEP2 ZNF628 ZNF275 ZNF491 ZNF551 ZSCAN29 ZSCAN32 ZNF469 ZNF878 SALL1 ZNF425 ZNF791	1.46e-03	693	118	12	PF00096
Domain	DAGK_acc	DGKB DGKZ	1.72e-03	10	118	2	PF00609
Domain	JmjN	KDM4C KDM4B	1.72e-03	10	118	2	SM00545
Domain	Diacylglycerol_kin_accessory	DGKB DGKZ	1.72e-03	10	118	2	IPR000756
Domain	JmjN	KDM4C KDM4B	1.72e-03	10	118	2	PF02375
Domain	JMJN	KDM4C KDM4B	1.72e-03	10	118	2	PS51183
Domain	DAGKa	DGKB DGKZ	1.72e-03	10	118	2	SM00045
Domain	JmjN	KDM4C KDM4B	1.72e-03	10	118	2	IPR003349
Domain	Znf_C2H2	HIVEP2 ZNF628 ZNF275 ZNF365 ZNF491 ZNF551 ZSCAN29 ZSCAN32 ZNF469 ZNF878 SALL1 ZNF425 ZNF791	1.73e-03	805	118	13	IPR007087
Domain	ZnF_C2H2	HIVEP2 ZNF628 ZNF275 ZNF365 ZNF491 ZNF551 ZSCAN29 ZSCAN32 ZNF469 ZNF878 SALL1 ZNF425 ZNF791	1.78e-03	808	118	13	SM00355
Domain	SCY	CCL3 CCL13 CCL23	2.36e-03	42	118	3	SM00199
Domain	Znf_FYVE_PHD	KDM4C NSD1 MTMR4 FGD6 KDM4B	2.42e-03	147	118	5	IPR011011
Domain	PHD	KDM4C NSD1 KDM4B RAI1	2.45e-03	89	118	4	SM00249
Domain	Znf_PHD	KDM4C NSD1 KDM4B RAI1	2.65e-03	91	118	4	IPR001965
Domain	Chemokine_IL8-like_dom	CCL3 CCL13 CCL23	2.70e-03	44	118	3	IPR001811
Domain	IL8	CCL3 CCL13 CCL23	2.70e-03	44	118	3	PF00048
Domain	ZF_PHD_2	KDM4C NSD1 KDM4B RAI1	3.10e-03	95	118	4	PS50016
Domain	ZF_PHD_1	KDM4C NSD1 KDM4B RAI1	3.22e-03	96	118	4	PS01359
Domain	PH	RASA1 MYO10 IRS1 FGD6 PREX1 AGAP3	3.35e-03	229	118	6	PF00169
Domain	DAGKc	DGKB DGKZ	3.43e-03	14	118	2	SM00046
Domain	ZINC_FINGER_C2H2_2	HIVEP2 ZNF628 ZNF275 ZNF491 ZNF551 ZSCAN29 ZSCAN32 ZNF469 ZNF878 SALL1 ZNF425 ZNF791	3.65e-03	775	118	12	PS50157
Domain	ZINC_FINGER_C2H2_1	HIVEP2 ZNF628 ZNF275 ZNF491 ZNF551 ZSCAN29 ZSCAN32 ZNF469 ZNF878 SALL1 ZNF425 ZNF791	3.73e-03	777	118	12	PS00028
Domain	Diacylglycerol_kinase_cat_dom	DGKB DGKZ	3.94e-03	15	118	2	IPR001206
Domain	DAGK	DGKB DGKZ	3.94e-03	15	118	2	PS50146
Domain	DAGK_cat	DGKB DGKZ	3.94e-03	15	118	2	PF00781
Domain	Znf_C2H2/integrase_DNA-bd	HIVEP2 ZNF628 ZNF491 ZNF551 ZSCAN29 ZSCAN32 ZNF469 ZNF878 SALL1 ZNF425 ZNF791	4.50e-03	694	118	11	IPR013087
Domain	Znf_C2H2-like	HIVEP2 ZNF628 ZNF365 ZNF491 ZNF551 ZSCAN29 ZSCAN32 ZNF469 ZNF878 SALL1 ZNF425 ZNF791	4.52e-03	796	118	12	IPR015880
Domain	NAD/diacylglycerol_kinase	DGKB DGKZ	5.06e-03	17	118	2	IPR016064
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TCF7L2 HIVEP2 CALD1 RASA1 ADGRV1 ESCO1 NSRP1 BICD1 OR51E2 PHKB SENP1 EFNA5 CBFA2T2 KNDC1 PARD3 MAML3 FAM162A KDM4B RAI1 AGAP3 RPAP2	3.87e-08	1489	120	21	28611215
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CYLD CASP8AP2 SNRK ADGRV1 DST ARHGEF10 NAV2 PREX1 KDM4B	9.49e-08	225	120	9	12168954
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CYLD HIVEP2 PAK4 HJURP IRS1 CDCA2 MTMR4 DST MAST4 ARHGEF10 NAV2 KIF2A PARD3 FGD6 AGAP3	3.02e-07	861	120	15	36931259
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HIVEP2 ZNF628 MYO10 NSD1 IRS1 CABLES1 ORC1 IGF2R DST NAV2 PYGB ANKRD33B PREX1 RAI1 AGAP3	6.50e-06	1105	120	15	35748872
Pubmed	Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.	TGM2 IGHM	1.18e-05	2	120	2	22451718
Pubmed	Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity.	KDM4C KDM4B	1.18e-05	2	120	2	24361252
Pubmed	Study on the expression of PAK4 and P54 protein in breast cancer.	PAK4 NONO	1.18e-05	2	120	2	27297086
Pubmed	Isoform-selective regulation of glycogen phosphorylase by energy deprivation and phosphorylation in astrocytes.	PYGB PYGM	1.18e-05	2	120	2	25130497
Pubmed	Characterization of a family of RanBP2-type zinc fingers that can recognize single-stranded RNA.	RANBP2 ZRANB2	1.18e-05	2	120	2	21256132
Pubmed	Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.	CYLD MSH3 HELB PYGB NONO	1.33e-05	87	120	5	17148452
Pubmed	Pellino-2 in nonimmune cells: novel interaction partners and intracellular localization.	MYO10 IRS1 TGM2	1.42e-05	14	120	3	34674267
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	CYLD MED16 RRP1 CDCA2 PHKB DST ACTR6 KDM4B RAI1 MPG RPAP2	1.53e-05	645	120	11	25281560
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RANBP2 MED16 MKRN1 NSD1 DGKZ RRP1 ORC1 DST CRACDL ZRANB2 KIF2A PARD3 NONO PREX1 NR1I3 AGAP3 MPG	1.56e-05	1497	120	17	31527615
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CASP8AP2 PAK4 SANBR SNRK ADGRV1 DST MAST4 NAV2 KDM4B RAI1	1.59e-05	529	120	10	14621295
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	CYLD TMEM248 PAK4 HJURP NSD1 DGKZ ST3GAL2 PHKB STK11 IGF2R TEX264 KIF2A PARD3 DDX39A	2.34e-05	1084	120	14	11544199
Pubmed	Interaction network of human early embryonic transcription factors.	RANBP2 TCF7L2 HIVEP2 MNX1 MSH3 SALL1 WDR6 RAI1	3.13e-05	351	120	8	38297188
Pubmed	Tissue transglutaminase clusters soluble A-type ephrins into functionally active high molecular weight oligomers.	TGM2 EFNA5	3.53e-05	3	120	2	17707797
Pubmed	Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.	KDM4C EFNA5	3.53e-05	3	120	2	22072270
Pubmed	Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells.	KDM4C KDM4B	3.53e-05	3	120	2	17611647
Pubmed	New biomarkers to predict the evolution of in situ breast cancers.	HJURP TGM2	3.53e-05	3	120	2	25243117
Pubmed	Pro-oncogenic Roles of HLXB9 Protein in Insulinoma Cells through Interaction with Nono Protein and Down-regulation of the c-Met Inhibitor Cblb (Casitas B-lineage Lymphoma b).	MNX1 NONO	3.53e-05	3	120	2	26342078
Pubmed	Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development.	KDM4C KDM4B	3.53e-05	3	120	2	27266524
Pubmed	Association of LKB1 with a WD-repeat protein WDR6 is implicated in cell growth arrest and p27(Kip1) induction.	STK11 WDR6	3.53e-05	3	120	2	17216128
Pubmed	The histone demethylase JMJD2C is stage-specifically expressed in preimplantation mouse embryos and is required for embryonic development.	KDM4C KDM4B	3.53e-05	3	120	2	19696013
Pubmed	The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance.	KDM4C KDM4B	3.53e-05	3	120	2	31434704
Pubmed	Whole Exome Sequencing Reveals Homozygous Mutations in RAI1, OTOF, and SLC26A4 Genes Associated with Nonsyndromic Hearing Loss in Altaian Families (South Siberia).	OTOF RAI1	3.53e-05	3	120	2	27082237
Pubmed	Histone demethylase JMJD2B and JMJD2C induce fibroblast growth factor 2: mediated tumorigenesis of osteosarcoma.	KDM4C KDM4B	3.53e-05	3	120	2	25636512
Pubmed	Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis.	CCL3 CCL13 CCL23	3.73e-05	19	120	3	10438970
Pubmed	A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.	TCF7L2 DGKB IRS1 GRHL3	4.01e-05	55	120	4	22581228
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	CASP8AP2 RANBP2 TCF7L2 NSD1 MSH3 ESCO1 RRP1 ZSCAN29 CDCA2 ORC1 DST ACTR6 NONO RAI1 MPG	4.08e-05	1294	120	15	30804502
Pubmed	A 2-Mb YAC/BAC-based physical map of the ovum mutant (Om) locus region on mouse chromosome 11.	CCL3 CCL13 CCL23	4.37e-05	20	120	3	10995569
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	PAK4 NSD1 DGKB IRS1 LRP1B TGM2 SENP1 MTMR4 ADAMTS15 PLCB3 NONO	4.73e-05	730	120	11	34857952
Pubmed	IL-2-induced proliferative response is controlled by loci Cinda1 and Cinda2 on mouse chromosomes 11 and 12: a distinct control of the response induced by different IL-2 concentrations.	CCL3 CCL13 CCL23	5.88e-05	22	120	3	9177770
Pubmed	Organization and chromosomal mapping of mouse Gh/tissue transglutaminase gene (Tgm2).	TGM2 PYGB	7.05e-05	4	120	2	10334875
Pubmed	G-protein-activated phospholipase C-beta, new partners for cell polarity proteins Par3 and Par6.	PLCB3 PARD3	7.05e-05	4	120	2	15782111
Pubmed	Transcription factor-7-like 2 (TCF7L2) gene acts downstream of the Lkb1/Stk11 kinase to control mTOR signaling, β cell growth, and insulin secretion.	TCF7L2 STK11	7.05e-05	4	120	2	29967064
Pubmed	Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.	KDM4C KDM4B	7.05e-05	4	120	2	27257215
Pubmed	A novel IRS-1-associated protein, DGKζ regulates GLUT4 translocation in 3T3-L1 adipocytes.	DGKZ IRS1	7.05e-05	4	120	2	27739494
Pubmed	The histone demethylase Kdm4 suppresses activation of hepatic stellate cell by inducing MiR-29 transcription.	KDM4C KDM4B	7.05e-05	4	120	2	31014673
Pubmed	Gastrointestinal stromal tumors with BRAF gene fusions. A report of two cases showing low or absent KIT expression resulting in diagnostic pitfalls.	MKRN1 AGAP3	7.05e-05	4	120	2	34398495
Pubmed	αv Integrins regulate germinal center B cell responses through noncanonical autophagy.	IGHM RUBCN	7.05e-05	4	120	2	29999501
Pubmed	Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha.	KDM4C KDM4B	7.05e-05	4	120	2	18713068
Pubmed	A protein interaction landscape of breast cancer.	CALD1 IRS1 MSH3 STK11 TGM2 IGF2R DST NAV2 MPG RPAP2	7.27e-05	634	120	10	34591612
Pubmed	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	CYLD SANBR ZNF365 CCL13	9.25e-05	68	120	4	22412388
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	CWF19L2 RANBP2 RBM45 MED16 NSRP1 RRP1 ZSCAN29 DST ZRANB2 KIF2A DDX39A NONO MPG	9.64e-05	1082	120	13	38697112
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	TCF7L2 KDM4C MYO10 ZNF365 ESCO1 ORC1 GAS2L2 ACTR6 CRACDL ZRANB2 ZNF791 KDM4B MPG RPAP2	1.01e-04	1242	120	14	30973865
Pubmed	Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight.	TCF7L2 DGKB IRS1	1.10e-04	27	120	3	20490451
Pubmed	Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.	DGKB DGKZ	1.17e-04	5	120	2	22627129
Pubmed	Gestational diabetes mellitus shares polymorphisms of genes associated with insulin resistance and type 2 diabetes in the Greek population.	TCF7L2 IRS1	1.17e-04	5	120	2	20540670
Pubmed	ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK).	RASA1 IRS1	1.17e-04	5	120	2	9174053
Pubmed	Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling.	RASA1 IRS1	1.17e-04	5	120	2	11604231
Pubmed	Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family.	KDM4C KDM4B	1.17e-04	5	120	2	21914792
Pubmed	Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.	KDM4C KDM4B	1.17e-04	5	120	2	16738407
Pubmed	Relationship of five type 2 diabetes candidate gene polymorphisms to the age at diagnosis of diabetes in the Slovakian population.	TCF7L2 IRS1	1.17e-04	5	120	2	20437825
Pubmed	Selective binding of the truncated form of the chemokine CKbeta8 (25-99) to CC chemokine receptor 1(CCR1).	CCL3 CCL23	1.17e-04	5	120	2	10660125
Pubmed	Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription.	TCF7L2 CBFA2T2	1.17e-04	5	120	2	18039847
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	BICD1 PHKB SENP1 PRR14L AGAP3	1.25e-04	139	120	5	25476789
Pubmed	Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2.	RANBP2 SENP1	1.75e-04	6	120	2	22194619
Pubmed	Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.	BICD1 PARD3	1.75e-04	6	120	2	20709820
Pubmed	Identification and characterization of JMJD2 family genes in silico.	KDM4C KDM4B	1.75e-04	6	120	2	15138608
Pubmed	β-catenin inhibits promyelocytic leukemia protein tumor suppressor function in colorectal cancer cells.	RANBP2 TCF7L2	1.75e-04	6	120	2	22155184
Pubmed	Differential release of MIP-1alpha and eotaxin during infection of mice by Histoplasma capsulatum or inoculation of beta-glucan.	CCL3 CCL13	1.75e-04	6	120	2	15316665
Pubmed	Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways.	CCL3 CCL13	1.75e-04	6	120	2	10072545
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	NUF2 ZNF365 BICD1 DST BICRAL	1.84e-04	151	120	5	17043677
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	MYO10 POLH ADGRV1 ESCO1 BICD1	1.90e-04	152	120	5	34299191
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	TCF7L2 RRP1 SENP1 TEX264 ZRANB2 NONO MAML3 RAI1	1.95e-04	457	120	8	32344865
Pubmed	Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.	TCF7L2 LRP1B PYGB	2.03e-04	33	120	3	24159190
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RANBP2 MSH3 CDCA2 ORC1 TGM2 DST WDR6 PYGB PRR14L KIF2A PARD3 DDX39A NONO MPG	2.44e-04	1353	120	14	29467282
Pubmed	Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling.	PAK4 PARD3	2.45e-04	7	120	2	18319301
Pubmed	Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate.	SNRK STK11	2.45e-04	7	120	2	15733851
Pubmed	Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.	KDM4C KDM4B	2.45e-04	7	120	2	28262558
Pubmed	Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development.	KDM4C KDM4B	2.45e-04	7	120	2	21445275
Pubmed	TGF-betaRII, BAX, IGFIIR, caspase-5, hMSH3 and hMSH6 alterations are not associated with microsatellite instability or p53 mutations in invasive urothelial carcinoma of the urinary bladder.	MSH3 IGF2R	2.45e-04	7	120	2	17676485
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	TCF7L2 POLH NSD1 MSH3 RRP1 CDCA2 KDM4B RAI1 MPG	2.69e-04	608	120	9	36089195
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	RANBP2 TCF7L2 MED16 HJURP IRS1 ZNF275 NSRP1 RRP1 ZNF551 SENP1 IGF2R TEX264 NONO	2.72e-04	1203	120	13	29180619
Pubmed	CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist.	CCL3 CCL13	3.26e-04	8	120	2	10477718
Pubmed	Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.	TCF7L2 IRS1	3.26e-04	8	120	2	19734900
Pubmed	Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice.	RAD54L MPG	3.26e-04	8	120	2	9607915
Pubmed	Identification of potential nuclear reprogramming and differentiation factors by a novel selection method for cloning chromatin-binding proteins.	MKRN1 NSD1	3.26e-04	8	120	2	15522233
Pubmed	CYLD coordinates with EB1 to regulate microtubule dynamics and cell migration.	CYLD STK11	3.26e-04	8	120	2	24552808
Pubmed	Guanosine triphosphatase-activating protein-associated protein, but not src-associated protein p68 in mitosis, is a part of insulin signaling complexes.	RASA1 IRS1	3.26e-04	8	120	2	9564850
Pubmed	Genome-wide association study of chronic periodontitis in a general German population.	LRP1B IGF2R ADAMTS15 KDM4B	3.50e-04	96	120	4	24024966
Pubmed	Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.	RANBP2 MYO10 PARD3 NONO	3.94e-04	99	120	4	27746211
Pubmed	Proteomic identification of brain proteins that interact with dynein light chain LC8.	MYO10 POLH PARD3	4.17e-04	42	120	3	14760703
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KDM4C MYO10 DGKB DST	4.25e-04	101	120	4	9872452
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	MED16 PAK4 ESCO1 RAD54L RAI1 MPG	4.46e-04	281	120	6	24163370
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	RANBP2 CALD1 MSH3 RRP1 TGM2 DST KIF2A DDX39A NONO	4.88e-04	660	120	9	32780723
Pubmed	Insulin-like growth factor axis gene polymorphisms and clinical outcomes in pancreatic cancer.	IRS1 IGF2R	5.22e-04	10	120	2	20416304
Pubmed	Insulin-like growth factor axis gene polymorphisms modify risk of pancreatic cancer.	IRS1 IGF2R	5.22e-04	10	120	2	21852217
Pubmed	Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse.	KDM4C KDM4B	5.22e-04	10	120	2	27023172
Pubmed	A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function.	ADGRV1 OTOF	5.22e-04	10	120	2	17329413
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SANBR ZNF469 MAML3 RAI1	5.29e-04	107	120	4	11347906
Pubmed	Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.	RANBP2 CDCA2 KIAA1210 IGF2R	5.87e-04	110	120	4	37219487
Pubmed	Chemokine/chemokine receptor nomenclature.	CCL3 CCL13 CCL23	6.19e-04	48	120	3	12080938
Pubmed	Genomic organization of the genes for human and mouse CC chemokine LEC.	CCL3 CCL23	6.36e-04	11	120	2	10235110
Pubmed	Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.	KDM4C KDM4B	6.36e-04	11	120	2	19144645
Pubmed	Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling.	DGKB DGKZ	6.36e-04	11	120	2	17021016
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KDM4C NSD1 KDM4B	6.57e-04	49	120	3	34368113
Pubmed	The protein interaction landscape of the human CMGC kinase group.	RANBP2 MED16 PAK4 SANBR NSRP1 CABLES1 WDR6 ZRANB2 DDX39A	7.05e-04	695	120	9	23602568
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	CYLD HIVEP2 RBM45 MYO10 STK11 IGF2R ARHGEF10 IGHM ZRANB2 DDX39A RPAP2	7.36e-04	1005	120	11	19615732
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	HIVEP2 ZNF628 ZNF275 ZNF365 ZNF491 ZNF551 ZSCAN29 ZSCAN32 ZNF469 ZNF878 SALL1 ZNF425 ZNF791	7.15e-06	718	75	13	28
GeneFamily	Glycogen phosphorylases	PYGB PYGM	5.08e-05	3	75	2	437
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASA1 MYO10 IRS1 FGD6 PREX1 AGAP3	2.13e-04	206	75	6	682
GeneFamily	EF-hand domain containing\|Diacylglycerol kinases	DGKB DGKZ	7.48e-04	10	75	2	1178
GeneFamily	Chemokine ligands\|Endogenous ligands	CCL3 CCL13 CCL23	8.58e-04	45	75	3	483
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF10 FGD6 PREX1	2.60e-03	66	75	3	722
GeneFamily	Zinc fingers RANBP2-type \|RNA binding motif containing	RANBP2 ZRANB2	3.39e-03	21	75	2	89
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM4C KDM4B	4.42e-03	24	75	2	485
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	MTMR4 FGD6	7.30e-03	31	75	2	81
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	RANBP2 TCF7L2 HIVEP2 RASA1 KDM4C MYO10 IRS1 MSH3 BICD1 IGF2R EFNA5 DST ARHGEF10 BICRAL KIF2A PARD3	1.51e-06	856	118	16	M4500
Coexpression	LINDGREN_BLADDER_CANCER_CLUSTER_1_DN	MNX1 ST3GAL2 RRP1 CDCA2 ORC1 NAV2 CCL13 PREX1 RUBCN RAD54L	8.46e-06	378	118	10	M17788
Coexpression	BENPORATH_NANOG_TARGETS	CYLD TCF7L2 CALD1 RASA1 MKRN1 ST3GAL2 ZNF551 CABLES1 ORC1 ZSCAN32 FBLN1 SALL1 WDR6 DDX39A UBE2W RAI1	9.34e-06	988	118	16	M6616
Coexpression	GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_UP	CASP8AP2 RASA1 SNRK KIF2A CCL13 RAD54L RAI1	3.50e-05	200	118	7	M3830
Coexpression	GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_1H_DN	REXO5 RASA1 ST3GAL2 ESCO1 IGF2R PYGM GRHL3	3.50e-05	200	118	7	M6949
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	REXO5 POLH HJURP NUF2 CDCA2 FBXO43 DDX39A RAD54L	3.73e-08	185	119	8	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	REXO5 POLH HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	5.39e-08	194	119	8	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	REXO5 HJURP NUF2 CDCA2 ORC1 FBXO43 NAV2 RAD54L	5.83e-08	196	119	8	6d80e23f6a1725a3f5ea7263233c55c2ea56f977
ToppCell	BAL-Control-Myeloid-Myeloid\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	REXO5 HJURP NUF2 CDCA2 ORC1 FBXO43 NAV2 RAD54L	5.83e-08	196	119	8	bf1d3fae8c01bb3d17c2dafad92b94937c663acd
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	REXO5 HJURP NUF2 CDCA2 ORC1 FBXO43 NAV2 RAD54L	5.83e-08	196	119	8	3dd7ed1dfac8d90c8a44f0ae00128bb46d9ef496
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	REXO5 HJURP NUF2 CDCA2 ORC1 FBXO43 NAV2 RAD54L	5.83e-08	196	119	8	4f649e3bfd21f21682678828673843a7d51c4ff2
ToppCell	BAL-Control-Myeloid-Myeloid\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	REXO5 HJURP NUF2 CDCA2 ORC1 FBXO43 NAV2 RAD54L	5.83e-08	196	119	8	799c290fb3dfacb666dd0dc3c43ec8a86b697ec7
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	REXO5 HJURP NUF2 CDCA2 ORC1 FBXO43 NAV2 RAD54L	5.83e-08	196	119	8	0c003a767c3b58605099dab64b9df0d8e5d8bc4b
ToppCell	Control-Myeloid-proliferating_Myeloid_cells\|Control / Disease group,lineage and cell class （2021.01.30）	REXO5 HJURP NUF2 CDCA2 ORC1 FBXO43 NAV2 RAD54L	6.06e-08	197	119	8	ddbe3fe078766bb55f0d7ca1aeb8f9e4aa696d8e
ToppCell	IIH-cycling-\|IIH / Condition, Cell_class and T cell subcluster	HJURP NUF2 LRP1B CDCA2 ORC1 FBXO43 RAD54L	5.82e-07	181	119	7	7f4fed9e296bc22cb5a1e6c8e3c4b641e97c3078
ToppCell	IIH-cycling\|IIH / Condition, Cell_class and T cell subcluster	HJURP NUF2 LRP1B CDCA2 ORC1 FBXO43 RAD54L	5.82e-07	181	119	7	ec3e782ce93dcfe1a54fb7284e4e39063614b0e2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	REXO5 POLH HJURP NUF2 CDCA2 FBXO43 RAD54L	7.24e-07	187	119	7	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	REXO5 POLH HJURP NUF2 CDCA2 FBXO43 NAV2	8.64e-07	192	119	7	27723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	REXO5 POLH HJURP NUF2 CDCA2 FBXO43 NAV2	8.64e-07	192	119	7	0a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	CALD1 MYO10 TGM2 FBLN1 DST NAV2 PARD3	9.59e-07	195	119	7	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HJURP NUF2 CDCA2 ORC1 CCL3 DDX39A RAD54L	1.06e-06	198	119	7	4909a97c62702704a0327b9a2cd73f048c8afeb6
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HJURP NUF2 CDCA2 ORC1 FBXO43 DDX39A RAD54L	1.06e-06	198	119	7	ddec07c7bc26d35f155537d907b46e2cb5b55b5f
ToppCell	T_cells-GZMK+GZMB+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	HJURP NUF2 CDCA2 IGHM FBXO43 CCL3 RAD54L	1.06e-06	198	119	7	085ba270f9defbf5ef45108c6d870e1d7c428479
ToppCell	proximal-Epithelial-Proliferating_Basal\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L FGFBP1	1.10e-06	199	119	7	521ff4ae3437c8ba477a0a42b9da195af976c3ff
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	POLH HJURP NUF2 CDCA2 IGHM FBXO43 DDX39A	1.10e-06	199	119	7	c9d15c84b9f8c87b4ea0008be7d5efc5f45efd1a
ToppCell	tumor_Lung-T/NK_cells-Undetermined\|tumor_Lung / Location, Cell class and cell subclass	HJURP NUF2 CDCA2 ORC1 FBXO43 DDX39A RAD54L	1.10e-06	199	119	7	2e222e2e080bc2be63d0fdf285e1790676b911ef
ToppCell	proximal-Epithelial-Proliferating_Basal-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L FGFBP1	1.10e-06	199	119	7	e8549b2c4152cb23548351d9cee27c3805892cd8
ToppCell	proximal-3-Epithelial-Proliferating_Basal\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L FGFBP1	1.10e-06	199	119	7	2263bb73d9c5693b44d91d2548305efc1b6e4079
ToppCell	tumor_Lung-T/NK_cells-Undetermined\|T/NK_cells / Location, Cell class and cell subclass	HJURP NUF2 CDCA2 ORC1 FBXO43 DDX39A RAD54L	1.14e-06	200	119	7	a1ef1b4824b2d56f6b2af15d698f58fc5590c392
ToppCell	390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	HJURP NUF2 ZNF491 OR51E2 FBXO43 RAD54L	4.42e-06	159	119	6	0fbfdb18b7ed4bde077add13f2b3636e144b254f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	REXO5 HJURP CTRC NUF2 CDCA2 FBXO43	5.47e-06	165	119	6	eec2d327c94832d1390314c93ef6a2be4648478b
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HJURP BICD1 CDCA2 ORC1 WDR6 RAD54L	5.67e-06	166	119	6	21ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCell	droplet-Heart-nan-18m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HJURP KCP ADGRV1 ZNF365 FBLN1 MTMR4	5.67e-06	166	119	6	9adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HJURP NUF2 CDCA2 ORC1 FBXO43 NAV2	5.86e-06	167	119	6	bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	POLH HJURP NUF2 CDCA2 FBXO43 RAD54L	6.28e-06	169	119	6	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	droplet-Lung-nan-3m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HJURP NUF2 PKD1L3 CDCA2 ORC1 RAD54L	6.28e-06	169	119	6	df2c9c706bfc9db2bc5726602a49f5f5a94e9481
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HJURP NUF2 PKD1L3 CDCA2 ORC1 RAD54L	6.28e-06	169	119	6	f6a6d2f614d60395ad9b867ff1cf59eba72b04ce
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HJURP NUF2 CDCA2 FBXO43 NAV2 RAD54L	6.72e-06	171	119	6	c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	REXO5 HJURP NUF2 CDCA2 FBXO43 RAD54L	7.42e-06	174	119	6	84da9faff088d05233183b425385beb054c92d1b
ToppCell	COVID-19_Convalescent-PLT_1\|World / Disease Group and Platelet Clusters	CWF19L2 MSH3 ZNF275 PLCB3 KDM4B RPAP2	8.72e-06	179	119	6	d0f2764c6fc5d61fd69e9231b3603a80ac373f65
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYLD TLR10 IGHM DNAH8 ANKRD33B KDM4B	9.29e-06	181	119	6	d66838fca0429cad2079cd8d92a5cd33eb0d3522
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	REXO5 POLH HJURP NUF2 CDCA2 FBXO43	9.59e-06	182	119	6	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	9.89e-06	183	119	6	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	HJURP NUF2 CDCA2 FBLN1 DST RAD54L	1.05e-05	185	119	6	9d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCell	Dividing_Macrophages-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	HJURP KCP NUF2 CDCA2 ORC1 FBXO43	1.08e-05	186	119	6	0067eb78d4c7e32b9563550d9fcaf13445ee6a48
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KCP ADGRV1 LRP1B EFNA5 SALL1 MAST4	1.12e-05	187	119	6	85e58a312fc325e4063a2d250666b99b8f99beb6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	REXO5 POLH HJURP NUF2 CDCA2 FBXO43	1.12e-05	187	119	6	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SNRK ADGRV1 BICD1 SALL1 MAST4 ANKRD33B	1.22e-05	190	119	6	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CALD1 RASA1 SNRK RRP1 DST IGHM	1.22e-05	190	119	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	wk_20-22-Hematologic_Lymphocytic-NK-Cycling_NK\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HJURP NUF2 CDCA2 FBXO43 DDX39A RAD54L	1.26e-05	191	119	6	5d4fed25bd318472a17228b12ade4c331865bda5
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.26e-05	191	119	6	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	POLH HJURP NUF2 CDCA2 FBXO43 DDX39A	1.26e-05	191	119	6	0ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	REXO5 HJURP NUF2 CDCA2 ORC1 RAD54L	1.26e-05	191	119	6	b85a0978dc1e8af4f49423f56dcfd52efce09ed1
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO10 ADGRV1 CABLES1 FBLN1 PYGM PARD3	1.30e-05	192	119	6	43beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	REXO5 POLH HJURP NUF2 CDCA2 FBXO43	1.30e-05	192	119	6	026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCell	Control-Lymphoid-Proliferating_CD4_T_cells\|Control / Condition, Lineage and Cell class	HJURP NUF2 CDCA2 FBXO43 NAV2 RAD54L	1.34e-05	193	119	6	33d409d6ed1c606337248587ad997ac5f67f081d
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CALD1 MYO10 FBLN1 DST ADAMTS15 NAV2	1.34e-05	193	119	6	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	normal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_DZ\|normal_Lymph_Node / Location, Cell class and cell subclass	HJURP NUF2 CDCA2 ORC1 DDX39A RAD54L	1.34e-05	193	119	6	5ce93860bc60ce6ecfed3a3d985f84e28781eec1
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	CABLES1 TGM2 DST CRACDL FGD6 MAML3	1.34e-05	193	119	6	826457e2aafdb61ead8a0a44d8cf9088d310684b
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.38e-05	194	119	6	f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MNX1 HJURP NUF2 CDCA2 ORC1 RAD54L	1.38e-05	194	119	6	17af04acd54dd6a895a966cbb4422de25dc4f1e6
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Pro-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.38e-05	194	119	6	3590ff471f74a361ee5bf02a58e3104cd3bf7d00
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MNX1 HJURP NUF2 CDCA2 ORC1 RAD54L	1.38e-05	194	119	6	3c385d93c5fe1a7817813c492f79fdb94d887357
ToppCell	3'_v3-blood-Lymphocytic_NK-Cycling_NK\|blood / Manually curated celltypes from each tissue	HJURP NUF2 CDCA2 ORC1 DDX39A RAD54L	1.38e-05	194	119	6	bf9734abaad603ade2a6a6940918aaf1e1c4e2cd
ToppCell	Control-Lymphoid_T/NK-T/NK_proliferative\|Control / Disease group, lineage and cell class	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.38e-05	194	119	6	9bbb124001fba7450f4639f47f9b720a483e7242
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.38e-05	194	119	6	a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.38e-05	194	119	6	17744fd6645cf5a447a01a83f07e8d305c2bcd9c
ToppCell	E15.5-Mesenchymal-developing_mesenchymal_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CALD1 HJURP NUF2 CDCA2 FBLN1 IGF2R	1.38e-05	194	119	6	d840c1949c328779426c9172e02da09e968f0567
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MNX1 HJURP NUF2 CDCA2 ORC1 RAD54L	1.38e-05	194	119	6	635d0e88f9c542a1d9363066c6cdbc6e44db76c1
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.38e-05	194	119	6	e14f66f7584909621b776292fbd52808273fd2ee
ToppCell	Healthy/Control-T/NK_proliferative\|Healthy/Control / Disease group and Cell class	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.42e-05	195	119	6	957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCell	Control-Lymphoid-Proliferating_CD4_T_cells\|Lymphoid / Condition, Lineage and Cell class	TCF7L2 HJURP NUF2 CDCA2 FBXO43 CCL23	1.42e-05	195	119	6	578bbb06a5476c08fc3b351cc580c551dfe53ae4
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	KDM4C ADGRV1 EFNA5 NAV2 PARD3 MAML3	1.46e-05	196	119	6	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	ADGRV1 LRP1B EFNA5 DST NAV2 PYGB	1.46e-05	196	119	6	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.46e-05	196	119	6	9d4f0a95e49bda25864cbe27e4e86096cba5609f
ToppCell	COVID-19-lung-Proliferative_fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	REXO5 HJURP NUF2 CDCA2 FBXO43 RAD54L	1.46e-05	196	119	6	2ce8a787f2731faa913d20342d73041d59468f27
ToppCell	COVID-19-lung-Proliferative_fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HJURP NUF2 CDCA2 FBLN1 FBXO43 RAD54L	1.46e-05	196	119	6	ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCell	Control-T/NK_proliferative\|Control / Disease condition and Cell class	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.46e-05	196	119	6	7b7bc25aef49bfd64f79303a92d527bf8188f7a6
ToppCell	Mild_COVID-19-T/NK-proliferating_T/NK\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.50e-05	197	119	6	5fd52fba2cb6fa67377f873da2ff6ce9c83b0591
ToppCell	wk_15-18-Hematologic_Lymphocytic-B-Large_pre-B\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	HJURP NUF2 CDCA2 IGHM DDX39A RAD54L	1.50e-05	197	119	6	7e0834b3947031bf244a10624dcf3f2095c79368
ToppCell	Healthy_Control-Lymphoid-T-Proliferating_T\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	HJURP NUF2 CDCA2 FBXO43 NAV2 RAD54L	1.50e-05	197	119	6	3ce3dcbbe0edeb5a6fb5596dd6c2b4d6c1d5159d
ToppCell	Healthy/Control-T/NK_proliferative\|World / Disease group and Cell class	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.50e-05	197	119	6	4a4d3083938783d6f5b87da02f10e501917da0b4
ToppCell	proximal-Hematologic-Proliferating_Macrophage\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HJURP NUF2 CDCA2 ORC1 CCL23 RAD54L	1.50e-05	197	119	6	0b1fa881abbfcc54b322fc27124db3f8947af016
ToppCell	wk_20-22-Hematologic_Lymphocytic-B-Large_pre-B\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HJURP NUF2 CDCA2 ORC1 IGHM RAD54L	1.50e-05	197	119	6	cebf47d66f425c84d3fea962e11f5bf4bfe2e60f
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.50e-05	197	119	6	d7a9296092153cf66426911fecd810f0c1ef978e
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.50e-05	197	119	6	dcff23240bb7cb652d7426b29355aa74442ef6fc
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.50e-05	197	119	6	434a5686a103bb766e0d80038413f0e12ea3981a
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HJURP NUF2 CDCA2 NAV2 CCL23 RAD54L	1.50e-05	197	119	6	76b61e60a757e58b465569538e632d6d9953e89a
ToppCell	Mild-Lymphoid-T-Proliferating_T\|Mild / Condition, Lineage, Cell class and cell subclass	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.50e-05	197	119	6	794517c70089da109f4c6489fe406c0ba6882b76
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.50e-05	197	119	6	6bddfa199ca812d9e518eaa02c3d4fb67e9f5b16
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.50e-05	197	119	6	c0a71a9452febda433bc544e4ac0a79c43dcf13e
ToppCell	BAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.50e-05	197	119	6	f34b1e34f1f0694564031077172c890b233ce8b7
ToppCell	proximal-3-Hematologic-Proliferating_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HJURP NUF2 CDCA2 ORC1 CCL23 RAD54L	1.50e-05	197	119	6	0dd9058aa19d1268ebba9a65555870224b5a5978
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Cycling_T\|lymph-node_spleen / Manually curated celltypes from each tissue	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.50e-05	197	119	6	aca6cbff7391ff550061bb7daa67fc5f6585806a
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	HJURP NUF2 CDCA2 GRHL3 RAD54L FGFBP1	1.50e-05	197	119	6	0a6754a5109bec0d0de42adbfdf4db43ff60c3d2
ToppCell	proximal-Hematologic-Proliferating_Macrophage-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HJURP NUF2 CDCA2 ORC1 CCL23 RAD54L	1.50e-05	197	119	6	9243617b307acf3df40d93c41cd8d4788699a7ea
ToppCell	Healthy_donor-T/NK_proliferative\|Healthy_donor / disease group, cell group and cell class (v2)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.50e-05	197	119	6	b6bbf87e5823fa66b4cad6a7be4f777356887b59
ToppCell	distal-Hematologic-Proliferating_NK/T-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.55e-05	198	119	6	5c14b152912429f099dfcb6bcb1aec80314a3284
ToppCell	distal-3-Hematologic-Proliferating_NK/T\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.55e-05	198	119	6	aa23119d73554733981df474648e59918d04edfc
ToppCell	COVID-19_Moderate-T/NK_proliferative\|World / disease group, cell group and cell class	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.55e-05	198	119	6	bf0131fbca6032e1aab4aa807f8c1d3be689cb7f
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	KDM4C ADGRV1 EFNA5 NAV2 PARD3 MAML3	1.55e-05	198	119	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	normal_Lung-T/NK_cells-Undetermined\|normal_Lung / Location, Cell class and cell subclass	HJURP NUF2 CDCA2 FBXO43 DDX39A RAD54L	1.55e-05	198	119	6	c65cdb54409087014125a76627e5efb5fe8dabc9
ToppCell	distal-1-Hematologic-Proliferating_Macrophage\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.55e-05	198	119	6	df3f5559ecd1f3cd1fd60e39dbad8741309e83a3
ToppCell	distal-Hematologic-Proliferating_Macrophage-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HJURP NUF2 CDCA2 ORC1 FBXO43 RAD54L	1.55e-05	198	119	6	2b0716e900bce54ad1825d6dcdaf4ebf31f355c4
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HJURP NUF2 CDCA2 ORC1 DDX39A RAD54L	1.55e-05	198	119	6	bcfe7b6d91f2e2f145cb2660b65fd2a6c1134b86
Computational	Cell ion homeostasis / chemokines.	CCL3 CCL13 CCL23	2.00e-04	19	66	3	MODULE_262
Computational	Genes in the cancer module 191.	CCL3 CCL13 CCL23	2.00e-04	19	66	3	MODULE_191
Drug	6-FPLP	OXCT2 PYGB PYGM	1.38e-06	5	119	3	CID000146246
Drug	6-FDPL	OXCT2 PYGB PYGM	1.38e-06	5	119	3	CID000129578
Drug	irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A	TCF7L2 HIVEP2 RASA1 MYO10 HJURP BICD1 MAST4 PARD3	3.78e-06	174	119	8	7530_DN
Drug	AC1Q6RZL	SNRK STK11 PYGB PYGM MPG	4.61e-06	47	119	5	CID000001144
Drug	6-fluoropyridoxal	OXCT2 PYGB PYGM	4.80e-06	7	119	3	CID003080803
Drug	Eburnamonine (-) [4880-88-0]; Down 200; 13.6uM; PC3; HT_HG-U133A	TCF7L2 HIVEP2 MNX1 ZNF365 ORC1 ZSCAN32 IGF2R KDM4B	7.22e-06	190	119	8	7154_DN
Drug	Mycophenolic acid [24280-93-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A	HJURP NSD1 MSH3 BICD1 EFNA5 BICRAL PARD3 KDM4B	7.51e-06	191	119	8	2857_DN
Drug	Oxantel pamoate [68813-55-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A	TCF7L2 BICD1 STK11 EFNA5 MAST4 NAV2 PARD3 RPAP2	9.07e-06	196	119	8	5338_UP
Drug	Harmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; HL60; HT_HG-U133A	TCF7L2 POLH NSD1 FBLN1 PLCB3 PRR14L PARD3 KDM4B	9.41e-06	197	119	8	2149_DN
Drug	Sulfadiazine [68-35-9]; Down 200; 16uM; PC3; HT_HG-U133A	TCF7L2 HIVEP2 MNX1 MED16 POLH ST3GAL2 ZSCAN32 KIF2A	9.41e-06	197	119	8	1810_DN
Drug	butyl rubber	OXCT2 CABLES1 GRHL3	1.14e-05	9	119	3	CID000062703
Drug	8-azidoadenosine 5'-monophosphate	PYGB PYGM MPG	1.63e-05	10	119	3	CID000124726
Drug	5'-deoxypyridoxal	OXCT2 PYGB PYGM	2.96e-05	12	119	3	CID000164889
Drug	Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; PC3; HT_HG-U133A	TCF7L2 HIVEP2 HJURP NSD1 ZNF365 MAST4 PARD3	4.11e-05	177	119	7	4652_DN
Drug	daunorubicin HCl; Down 200; 1uM; MCF7; HT_HG-U133A	HJURP BICD1 MAST4 NAV2 BICRAL PARD3 KDM4B	6.65e-05	191	119	7	7525_DN
Drug	Econazole nitrate [24169-02-6]; Down 200; 9uM; MCF7; HT_HG-U133A	TCF7L2 ST3GAL2 ZNF365 STK11 CBFA2T2 PLCB3 PRR14L	6.87e-05	192	119	7	7427_DN
Drug	(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; PC3; HT_HG-U133A	CALD1 MED16 KDM4C STK11 CBFA2T2 BICRAL RUBCN	7.33e-05	194	119	7	4524_DN
Drug	Cimetidine [51481-61-9]; Down 200; 15.8uM; PC3; HG-U133A	TCF7L2 PAK4 MAST4 ARHGEF10 WDR6 CBFA2T2 PYGB	7.33e-05	194	119	7	1884_DN
Drug	Metronidazole [443-48-1]; Down 200; 23.4uM; MCF7; HT_HG-U133A	CYLD MYO10 ST3GAL2 STK11 ZSCAN32 ARHGEF10 CBFA2T2	7.33e-05	194	119	7	4141_DN
Drug	Stachydrine hydrochloride; Down 200; 22.2uM; MCF7; HT_HG-U133A	MED16 POLH BICD1 TGM2 FBLN1 KDM4B RPAP2	7.33e-05	194	119	7	2743_DN
Drug	Menadione [58-27-5]; Down 200; 23.2uM; PC3; HT_HG-U133A	CYLD TCF7L2 HIVEP2 SNRK NAV2 BICRAL RUBCN	7.33e-05	194	119	7	4662_DN
Drug	butylethanolamine	PHKB PYGB PYGM	7.42e-05	16	119	3	CID000249006
Drug	Fusidic acid sodium salt [751-94-0]; Down 200; 7.4uM; HL60; HT_HG-U133A	MED16 PAK4 RRP1 PLCB3 CCL23 RUBCN RPAP2	7.57e-05	195	119	7	1293_DN
Drug	Pridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; PC3; HT_HG-U133A	TCF7L2 MED16 STK11 MAST4 BICRAL KIF2A KDM4B	7.82e-05	196	119	7	5860_DN
Drug	Benzonatate [104-31-4]; Down 200; 6.6uM; MCF7; HT_HG-U133A	CYLD MED16 BICD1 STK11 BICRAL UBE2W RAD54L	7.82e-05	196	119	7	1679_DN
Drug	Folic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A	TCF7L2 POLH ST3GAL2 BICD1 BICRAL PRR14L KDM4B	8.07e-05	197	119	7	7201_DN
Drug	Nafronyl oxalate [3200-06-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A	MED16 POLH NSD1 ST3GAL2 BICD1 BICRAL RPAP2	8.07e-05	197	119	7	5287_DN
Drug	3,5-dimethylphenyl isocyanate	PYGB PYGM	8.10e-05	3	119	2	CID000521488
Drug	5'-deoxy-5'-fluoro-5'-(methylthio)adenosine	PYGB PYGM	8.10e-05	3	119	2	CID000147839
Drug	NSC758405	PYGB PYGM	8.10e-05	3	119	2	CID000003201
Drug	3,5-dinitrophenyl phosphate	PYGB PYGM	8.10e-05	3	119	2	CID000151920
Drug	pyridoxal phosphoglucose	PYGB PYGM	8.10e-05	3	119	2	CID000196007
Drug	5-ethyl-4-hydroxy-2-methyl-3(2H)-furanone	PYGB PYGM	8.10e-05	3	119	2	CID000093111
Drug	adenosine-5'-chloromethylphosphonate	PYGB PYGM	8.10e-05	3	119	2	CID000191554
Drug	hydan	PYGB PYGM	8.10e-05	3	119	2	CID000008360
Drug	EHMF	PYGB PYGM	8.10e-05	3	119	2	CID000033931
Drug	pyridoxal 5'-methylenephosphonate	PYGB PYGM	8.10e-05	3	119	2	CID003082249
Drug	Plp 5'-mpa	PYGB PYGM	8.10e-05	3	119	2	CID003082151
Drug	glucose-1,2-cyclic phosphate	PYGB PYGM	8.10e-05	3	119	2	CID000191723
Drug	3'-FFdUrd	PYGB PYGM	8.10e-05	3	119	2	CID000072260
Drug	2',3',4',5,5'-pentachloro-2-biphenylol	PYGB PYGM	8.10e-05	3	119	2	CID000119518
Drug	AC1L8XK3	PYGB PYGM	8.10e-05	3	119	2	CID000409735
Drug	N-acetyl-N'-beta-D-glucopyranosyl urea	PYGB PYGM	8.10e-05	3	119	2	CID000446801
Drug	riboflavin tetraacetate	PYGB PYGM	8.10e-05	3	119	2	CID000094186
Drug	2,5-dimethyl-3-furanone	PYGB PYGM	8.10e-05	3	119	2	CID000085730
Drug	3,5-dinitrophenol	PYGB PYGM	8.10e-05	3	119	2	CID000011459
Drug	Lynestrenol [52-76-6]; Down 200; 14uM; MCF7; HT_HG-U133A	HIVEP2 MED16 POLH ST3GAL2 BICD1 STK11 RAD54L	8.33e-05	198	119	7	1537_DN
Drug	Ifenprodil tartrate [23210-58-4]; Up 200; 8.4uM; HL60; HT_HG-U133A	TCF7L2 MED16 STK11 CBFA2T2 PYGB PLCB3 KDM4B	8.33e-05	198	119	7	2372_UP
Drug	Clorgyline hydrochloride [17780-75-5]; Down 200; 13uM; MCF7; HT_HG-U133A	CYLD KDM4C MAST4 PLCB3 PRR14L KIF2A KDM4B	8.33e-05	198	119	7	3219_DN
Drug	Proxyphylline [603-00-9]; Down 200; 16.8uM; HL60; HT_HG-U133A	TCF7L2 MED16 PAK4 BICD1 STK11 FBLN1 KDM4B	8.60e-05	199	119	7	3115_DN
Drug	Diclofenac sodium [15307-79-6]; Down 200; 12.6uM; MCF7; HT_HG-U133A	TCF7L2 KDM4C POLH MSH3 CBFA2T2 NAV2 BICRAL	8.60e-05	199	119	7	7215_DN
Drug	Piperacetazine [3819-00-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A	TCF7L2 BICD1 STK11 MAST4 ARHGEF10 PARD3 KDM4B	8.60e-05	199	119	7	7191_DN
Drug	Cefazolin sodium salt [27164-46-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A	CYLD CALD1 MED16 ARHGEF10 CBFA2T2 PRR14L PARD3	8.60e-05	199	119	7	4708_DN
Drug	AC1L9IXX	MSH3 TGM2 EFNA5 GRHL3	8.96e-05	45	119	4	CID000446000
Drug	coproporphyrinogen I	RBM45 OXCT2 CTRC	1.07e-04	18	119	3	CID000440776
Drug	galocitabine	PYGB PYGM	1.61e-04	4	119	2	CID000065950
Drug	5-deoxyribose-1-phosphate	PYGB PYGM	1.61e-04	4	119	2	CID000135786
Drug	ingliforib	PYGB PYGM	1.61e-04	4	119	2	CID006451325
Drug	uric acid riboside	PYGB PYGM	1.61e-04	4	119	2	CID000164933
Drug	pseudo-dl-glucose	PYGB PYGM	1.61e-04	4	119	2	CID000125259
Drug	pyridoxal diphosphate	PYGB PYGM	1.61e-04	4	119	2	CID000125696
Drug	2,5-anhydro-D-mannitol 1-phosphate	PYGB PYGM	1.61e-04	4	119	2	CID000189134
Drug	AC1LAMW2	PYGB PYGM	1.61e-04	4	119	2	CID000491364
Drug	FdUrd-C8	PYGB PYGM	1.61e-04	4	119	2	CID000094262
Drug	Mem-CC	PYGB PYGM	1.61e-04	4	119	2	CID003081269
Drug	BCIp4A	PYGB PYGM	1.61e-04	4	119	2	CID000192417
Drug	3'-chloromethotrexate	PYGB PYGM	1.61e-04	4	119	2	CID000097703
Drug	Myomodulin	MNX1 EFNA5 CCL13	1.73e-04	21	119	3	CID000123654
Drug	Mgamp-pnp	CALD1 MYO10 ACTR6	1.73e-04	21	119	3	CID005311323
Drug	AC1L9IMU	PYGB PYGM MPG	2.28e-04	23	119	3	CID000445825
Drug	BrVarafUTP	POLH PYGB PYGM	2.60e-04	24	119	3	CID005273539
Drug	heptulose-2-P	PYGB PYGM	2.68e-04	5	119	2	CID000124823
Drug	gluconohydroximo-1,5-lactone	PYGB PYGM	2.68e-04	5	119	2	CID009576855
Drug	DHPBU	PYGB PYGM	2.68e-04	5	119	2	CID000125914
Drug	5'-isobutylthioinosine	PYGB PYGM	2.68e-04	5	119	2	CID003080910
Drug	indirubin-5-sulphonate	PYGB PYGM	2.68e-04	5	119	2	CID005288641
Drug	AC1LCUXJ	PYGB PYGM	2.68e-04	5	119	2	CID000656425
Drug	6-amino-5-bromouracil	PYGB PYGM	2.68e-04	5	119	2	CID000080578
Drug	etafenone	PYGB PYGM	2.68e-04	5	119	2	CID000003275
Drug	ddEtUrd	PYGB PYGM	2.68e-04	5	119	2	CID000451452
Drug	5-trifluoromethyl-2'-deoxycytidine	PYGB PYGM	2.68e-04	5	119	2	CID000125618
Drug	m-anisidine	PYGB PYGM	2.68e-04	5	119	2	CID000010824
Drug	2-hydroxypropylphosphonate	PYGB PYGM	2.68e-04	5	119	2	CID000441028
Drug	3'-O-methylpyridoxal 5'-phosphate	PYGB PYGM	2.68e-04	5	119	2	CID003082179
Drug	GlcMan	PYGB PYGM	2.68e-04	5	119	2	CID000152120
Drug	U66985	PYGB PYGM	2.68e-04	5	119	2	CID000127224
Drug	AC1O3M08	PYGB PYGM	2.68e-04	5	119	2	CID006331955
Drug	irinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A	TCF7L2 HIVEP2 MAST4 NAV2 PARD3 KDM4B	2.83e-04	171	119	6	7535_DN
Drug	AC1NSKHI	DGKZ STK11 ACTR6 PLCB3	2.94e-04	61	119	4	CID005311358
Disease	medulloblastoma (is_marker_for)	KDM4C KDM4B	1.44e-04	5	113	2	DOID:0050902 (is_marker_for)
Disease	Liver carcinoma	CYLD HJURP IRS1 NUF2 CDCA2 ORC1 IGF2R CCL3 RAD54L	1.50e-04	507	113	9	C2239176
Disease	macrophage inflammatory protein 1a measurement	ZNF365 SCUBE1 CCL3	2.50e-04	32	113	3	EFO_0008218
Disease	multiple myeloma (is_marker_for)	RANBP2 IGF2R NONO	3.56e-04	36	113	3	DOID:9538 (is_marker_for)
Disease	C-C motif chemokine 3-like 1 measurement	CCL3 CCL23	4.01e-04	8	113	2	EFO_0008052
Disease	alopecia areata (is_marker_for)	KDM4C KDM4B	6.41e-04	10	113	2	DOID:986 (is_marker_for)
Disease	neuroimaging measurement	TCF7L2 BICD1 ZNF469 MAST4 CBFA2T2 NAV2 PYGB PARD3 FGD6 KDM4B RAI1 AGAP3	8.25e-04	1069	113	12	EFO_0004346
Disease	Malignant mesothelioma	MTMR4 CCL3 CCL23 FGD6	8.33e-04	109	113	4	C0345967
Disease	pancreatic cancer (is_implicated_in)	TCF7L2 NUF2 STK11 RAD54L	9.21e-04	112	113	4	DOID:1793 (is_implicated_in)
Disease	peripheral arterial disease, traffic air pollution measurement	TCF7L2 HIVEP2 TLR10 NAV2 PYGB	9.22e-04	194	113	5	EFO_0004265, EFO_0007908
Disease	C-C motif chemokine 16 measurement	GAS2L2 CCL23	9.36e-04	12	113	2	EFO_0008044
Disease	sitting height ratio	TCF7L2 NSD1 CABLES1	9.96e-04	51	113	3	EFO_0007118
Disease	cortical thickness	TCF7L2 MSH3 ADGRV1 ZNF469 SCUBE1 EFNA5 MAST4 NAV2 PYGB PARD3 KDM4B AGAP3	1.17e-03	1113	113	12	EFO_0004840
Disease	femoral neck bone geometry	NSD1 KIF2A	1.28e-03	14	113	2	EFO_0004511
Disease	fourth ventricle volume measurement	CWF19L2 BICD1	1.68e-03	16	113	2	EFO_0010303
Disease	periodontitis	TCF7L2 LRP1B IGF2R OTOF KDM4B	1.71e-03	223	113	5	EFO_0000649
Disease	Glycogen storage disease	PHKB PYGM	1.90e-03	17	113	2	cv:C0017919
Disease	respiratory symptom change measurement, response to placebo	CDCA2 NAV2	1.90e-03	17	113	2	EFO_0008344, EFO_0010068
Disease	coronary artery disease	CWF19L2 TCF7L2 HIVEP2 PKD1L3 SCUBE1 SENP1 IGF2R MAST4 FGD6 PREX1 KDM4B RAI1	2.10e-03	1194	113	12	EFO_0001645
Disease	neuroticism measurement, wellbeing measurement, depressive symptom measurement	TCF7L2 MAML3	2.38e-03	19	113	2	EFO_0007006, EFO_0007660, EFO_0007869
Disease	corneal hysteresis	TCF7L2 ZNF469	2.64e-03	20	113	2	EFO_0010066
Disease	Fetal Growth Retardation	MNX1 ORC1	2.64e-03	20	113	2	C0015934
Disease	breast cancer (is_implicated_in)	TCF7L2 KDM4C KDM4B RAD54L	2.69e-03	150	113	4	DOID:1612 (is_implicated_in)
Disease	melanoma	KDM4C LRP1B STK11 KDM4B RAI1	2.71e-03	248	113	5	C0025202
Disease	vital capacity	HIVEP2 ZNF628 PKD1L3 CABLES1 SENP1 EFNA5 DST ADAMTS15 PARD3 FAM162A KDM4B AGAP3	2.79e-03	1236	113	12	EFO_0004312
Disease	migraine disorder, endometriosis	LRP1B CDCA2 FGD6	2.80e-03	73	113	3	EFO_0001065, MONDO_0005277
Disease	HIV-1 infection, Susceptibility to viral and mycobacterial infections	KDM4C NAV2	2.91e-03	21	113	2	EFO_0000180, Orphanet_391311
Disease	diaphragmatic hernia	CALD1 DGKB	2.91e-03	21	113	2	EFO_0008561
Disease	Nystagmus	MSH3 MAST4	2.91e-03	21	113	2	HP_0000639
Disease	age at first sexual intercourse measurement	TCF7L2 MKRN1 DGKZ EFNA5 MAML3 KDM4B	3.63e-03	383	113	6	EFO_0009749
Disease	Coronary heart disease	TCF7L2 IRS1	3.80e-03	24	113	2	C0010068
Disease	supramarginal gyrus volume measurement	CWF19L2 CRACDL	3.80e-03	24	113	2	EFO_0010332

Protein segments in the cluster

Peptide	Gene	Start	Entry
KVSGKSLPERRFFCS	C2orf42	211	Q9NWW7
ASLQGCRSAKDKTRL	AGAP3	606	Q96P47
PNCQFRSKTARLKTF	ACTR6	26	Q9GZN1
SDSECKNGIPRSFLR	ARHGEF10	286	O15013
LTKKGRRFCANPSDK	CCL23	86	P55773
SGTQRKRQFSPSLCD	BICD1	851	Q96G01
SRCPQKAVIFRTKLG	CCL13	56	Q99616
FSATLSKDIRPVCRK	DDX39A	226	O00148
FAGNPTSCLKLKDER	FGFBP1	96	Q14512
CSLINPKRKDTRGFS	ADGRV1	5696	Q8WXG9
SKTIPRRGKSTVCLD	CASP8AP2	966	Q9UKL3
SPRDKCKLICRANGT	ADAMTS15	611	Q8TE58
RKPAGSKNCLQRLTD	ANKRD33B	271	A6NCL7
KRSLEAGRCLPKSDS	HJURP	506	Q8NCD3
KNTTSSPCKGRAKRR	RAI1	1546	Q7Z5J4
KIESFGSPKGSVCRR	RANBP2	3201	P49792
CDRSFRAILAEPKNK	RBM45	181	Q8IUH3
VTRRNCGRSKPSSKL	NSD1	1016	Q96L73
EVPKCSFREARSGIK	NSRP1	196	Q9H0G5
CNLRKSSPGTSNKRL	RASA1	576	P20936
APSQLAKRKPEGRSC	RAD54L	6	Q92698
CKGFFRRTVSKSIGP	NR1I3	31	Q14994
SGNSEPKKCLRTRNV	MSH3	116	P20585
SGKPAARKALDRCSE	NONO	196	Q15233
SDGRSCKRPKNELFL	LRP1B	511	Q9NZR2
CDGNFSPTSKRIRKD	MAML3	181	Q96JK9
SGNRVLEAAKSCSKR	DST	3986	Q03001
NLLGKCRRPRTAFTS	MNX1	236	P50219
CGARQLSKLKRFLTT	CBFA2T2	111	O43439
QLPSKSERAKAFGTC	OR51E2	226	Q9H255
TADILCPKAKRTSRF	NUF2	106	Q9BZD4
LCSGFRKPTKNSEER	CWF19L2	401	Q2TBE0
CFSPVGEKFRARSLK	DNAH8	2951	Q96JB1
QSTKTFTPCERLEKR	MYO10	1866	Q9HD67
ERPRFCLLSKEEGKS	PDZD3	111	Q86UT5
GCPATLPSKSRQKTR	KDM4B	711	O94953
RSFQCARSTSKRPKA	KDM4C	371	Q9H3R0
KRSIPLESCFNINKR	IRS1	61	P35568
AKKFSVSSCRARPRP	CRACDL	571	Q6NV74
RLLSYGCCSKRPNSK	MTMR4	926	Q9NYA4
RCTTDLNRKDKFPAI	MED16	266	Q9Y2X0
TSCASLDSPGRIKRK	ORC1	251	Q13415
ESCGLKFNRSESIRP	PLCB3	191	Q01970
NTLGSFRCRPKLQCK	FBLN1	281	P23142
CSRGAAKPRNRKDAL	FBXO43	681	Q4G163
KKEFGPPSRRKSNCV	KIF2A	146	O00139
FRRKVKCPDSSNSGV	GRHL3	416	Q8TE85
KASRREPLKASQCSP	BICRAL	921	Q6AI39
SFGSRRGCNTRKKPV	CTRC	236	Q99895
NPRKSKLICQATGFS	IGHM	126	P01871
RCRTLSGSPRPKNFK	CABLES1	306	Q8TDN4
PNSDKAKACLSKGRR	GAS2L2	746	Q8NHY3
PKTGLFCSLVKRTRN	DGKB	786	Q9Y6T7
SRVLKDRELCSGPSK	MPG	206	P29372
QCSKPGVIFLTKRSR	CCL3	56	P10147
CPSAQGSKPKNFRLR	C16orf90	46	A8MZG2
PAANTDRRAEGKKCT	MAST4	2361	O15021
GSSDEPGKRRKSFCI	CDCA2	966	Q69YH5
PGKRRKSFCISTLAN	CDCA2	971	Q69YH5
SAIPDNGRRSCLKLK	EFNA5	141	P52803
APGKCSSFKEQLSPR	KIAA1210	1281	Q9ULL0
CKRLSEDGISRKSFP	KNDC1	1401	Q76NI1
TQGSEKCPQKTTRRD	ESCO1	221	Q5FWF5
EKINFRCKPSFRESG	DGKZ	146	Q13574
RVPSKTATGQRTCAK	H1-9P	96	P60008
CFSIFSTEGKRRPAK	GPR15L	16	Q6UWK7
ALFVKLKSCRPDSRF	CYLD	531	Q9NQC7
SRGAPESCNDKAKLR	RUBCN	416	Q92622
KCLSRAKTSPRAQLS	SCUBE1	406	Q8IWY4
PFRDRGKFKNTACDI	SALL1	991	Q9NSC2
LPKSRASKRTCGVND	HELB	1031	Q8NG08
SQKRFPSNCGRDGKL	PHKB	426	Q93100
LNRFPRGAKTAKQCT	OTOF	1851	Q9HC10
KGLRSPASIADKVFC	PRR14L	1861	Q5THK1
FCAQVSKEVPRRKSL	PAK4	461	O96013
ARRISKCNELKSPGS	PARD3	681	Q8TEW0
KANPSERRFGILSNC	MKRN1	291	Q9UHC7
CPDGIRKKSTTIRFT	IGF2R	1461	P11717
CTKTVGRPAFKRFDI	IGF2R	2096	P11717
KGRPSKLRQSNPEFC	TMEM248	291	Q9NWD8
NKLSDSVFRCLPKSI	TLR10	431	Q9BXR5
GPKDVERSRIFSKLC	TACO1	71	Q9BSH4
REANARCGVLKSSPF	KCP	1406	Q6ZWJ8
AASPKFCRSTLPRKQ	NAV2	1486	Q8IVL1
SRNFIRISSKGDKCL	PKD1L3	116	Q7Z443
RRRKLSTVPKCFLGN	PREX1	431	Q8TCU6
SGSCRRSLLSPKKTQ	SENP1	161	Q9P0U3
GLQRLSKERLSGKSC	ST3GAL2	56	Q16842
SQKRSEKPPAGSICR	RRP1	261	P56182
CSKNFPGKTALATRE	POLH	321	Q9Y253
PNPARKACSASSKIR	STK11	411	Q15831
ASRCLPNSKLKGLTF	THAP6	11	Q8TBB0
LRFDPTQLTKGCKVR	SANBR	446	Q6NSI8
RIPSASGRKKAFNTC	OR6J1	226	Q8NGC5
SLKPTASGRKCLFRV	SNRK	431	Q9NRH2
SSDLKRINGFCTKPQ	FAM162A	31	Q96A26
KKSTGCAFAVSPNLR	OXCT2	496	Q9BYC2
CFTPKGSSLKIEERA	CALD1	636	Q05682
PKFLKNAGRDCSRRS	TGM2	201	P21980
KECGKSFSARPAFRV	ZNF791	331	Q3KP31
QAESSRDLCRPPKKG	ZNF365	366	Q70YC5
RTPEQCRTKFKSLQL	ZSCAN32	301	Q9NX65
RFKSSKFGCRDPVRT	PYGM	311	P11217
APRCSRKAAGTKQTS	RPAP2	16	Q8IXW5
CNLRALKRLFKSFGP	REXO5	516	Q96IC2
RCNVLKKSASSFPRS	SPATA31D1	741	Q6ZQQ2
SCRSKVRGTSKPIFS	STYXL2	811	Q5VZP5
TDLSAPKKCRARFGL	TCF7L2	456	Q9NQB0
AKKRITFCPSRSLDE	FGD6	1186	Q6ZV73
SECGKSFSRKSNLIR	ZNF551	646	Q7Z340
VGRALQPVRKKFSDC	ERVK-8	176	P63133
RFKSSKFGCRDPVRT	PYGB	311	P11216
GRLFTESCSISPKLR	TEX264	61	Q9Y6I9
CFKSRSRPGTLKAVT	WDR6	341	Q9NNW5
PDKKCGNVNFARRTS	ZRANB2	16	O95218
RLPARAQAKSCTKGP	ZNF469	3751	Q96JG9
KECEKSFISPASIRR	ZNF491	106	Q8N8L2
LSSCKEKRRPPDNSF	UBE2W	116	Q96B02
RTPEQCRTKFKSLQT	ZSCAN29	456	Q8IWY8
ASTVSPSRERKKCFL	HIVEP2	1066	P31629
KKCFLVRQASFSGSP	HIVEP2	1076	P31629
PHCGKLFRRSSELTK	ZNF275	296	Q9NSD4
PECGRSFSRKAALKT	ZNF425	361	Q6IV72
DFVRKCFSSRKRTPN	THEGL	171	P0DJG4
CFSSRKRTPNLSKPK	THEGL	176	P0DJG4
KECGKAFRFPSSVRR	ZNF878	146	C9JN71
PDCPKAFKNSSSLRR	ZNF628	151	Q5EBL2