Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionheme binding

CYP26B1 CYP3A43 CYP17A1 FLVCR1 CYP4F2 PXDN GUCY1A2 CYP4F3

3.02e-051541578GO:0020037
GeneOntologyMolecularFunctiontetrapyrrole binding

CYP26B1 CYP3A43 CYP17A1 FLVCR1 CYP4F2 PXDN GUCY1A2 CYP4F3

4.73e-051641578GO:0046906
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

6.14e-0521572GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

6.14e-0521572GO:0097259
GeneOntologyBiologicalProcesspositive regulation of steroid biosynthetic process

CYP17A1 SREBF1 ABCG1 SCAP CSHL1

9.52e-06381565GO:0010893
GeneOntologyBiologicalProcesspositive regulation of steroid metabolic process

CYP17A1 SREBF1 ABCG1 SCAP CSHL1

1.58e-05421565GO:0045940
GeneOntologyBiologicalProcessactin filament-based process

NPHS1 CDC42BPG PDE4B CARMIL2 NEDD4L SYNPO2L OBSCN MYOZ2 SRCIN1 ARHGEF17 SHANK3 ARHGEF10L GJA1 ALMS1 NISCH SYNE2 SCN4A SCN8A CACNA1G TNXB

1.88e-0591215620GO:0030029
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

NPHS1 CARMIL2 NEDD4L BCL2L11 NUMBL PIEZO1 FPR2 AZU1 SYNPO2L DHX33 PLXND1 ATG2A NCAPG2 EMILIN1 SHANK3 ARHGEF10L LRP8 GJA1 ABCG1 VPS13D TTBK1 ALMS1 CERS1 CNOT1 TNXB

3.41e-05136615625GO:0051130
GeneOntologyBiologicalProcesscardiac muscle cell contraction

PDE4B NEDD4L GJA1 SCN4A SCN8A CACNA1G

7.53e-05931566GO:0086003
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

NPHS1 CARMIL2 NEDD4L BCL2L11 NUMBL MYCBP2 MCIDAS PIEZO1 SYNPO2L MARCHF7 SRCIN1 DHX33 ATG2A EMILIN1 SHANK3 ARHGEF10L GJA1 TTBK1 ALMS1 SYNE2 CNOT1 SORL1

9.09e-05118915622GO:0044087
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

NEDD4L GJA1 SCN4A SCN8A CACNA1G

1.06e-04621565GO:0086002
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

JPH4 CYP26B1 CYP3A43 CYP17A1 PIEZO1 TMEM199 SREBF1 CYP4F2 NCSTN ATG2A POM121C GJA1 ABCG1 UBXN4 SCAP SYNE2 TLR3 DISP3 CYP4F3 CERS1 TNPO3 NOTCH4 SORL1

1.80e-04132715923GO:0042175
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN4A SCN8A CACNA1G

2.72e-04171593GO:0001518
GeneOntologyCellularComponentendoplasmic reticulum membrane

JPH4 CYP26B1 CYP3A43 CYP17A1 PIEZO1 TMEM199 SREBF1 CYP4F2 NCSTN ATG2A POM121C GJA1 ABCG1 UBXN4 SCAP SYNE2 TLR3 DISP3 CYP4F3 CERS1 NOTCH4 SORL1

3.26e-04129315922GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

JPH4 CYP26B1 CYP3A43 CYP17A1 PIEZO1 TMEM199 SREBF1 CYP4F2 NCSTN ATG2A POM121C GJA1 ABCG1 UBXN4 SCAP SYNE2 TLR3 DISP3 CYP4F3 CERS1 NOTCH4 SORL1

3.47e-04129915922GO:0098827
GeneOntologyCellularComponentlamellipodium membrane

PIEZO1 PLXND1 SYNE2

5.98e-04221593GO:0031258
DomainCyt_P450_CS

CYP26B1 CYP3A43 CYP17A1 CYP4F2 CYP4F3

7.45e-05531545IPR017972
DomainCYTOCHROME_P450

CYP26B1 CYP3A43 CYP17A1 CYP4F2 CYP4F3

1.06e-04571545PS00086
Domain-

CYP26B1 CYP3A43 CYP17A1 CYP4F2 CYP4F3

1.15e-045815451.10.630.10
Domainp450

CYP26B1 CYP3A43 CYP17A1 CYP4F2 CYP4F3

1.15e-04581545PF00067
DomainCyt_P450

CYP26B1 CYP3A43 CYP17A1 CYP4F2 CYP4F3

1.35e-04601545IPR001128
DomainSSD

SCAP DISP3 DISP2

1.48e-04131543IPR000731
DomainSSD

SCAP DISP3 DISP2

1.48e-04131543PS50156
DomainLRRNT

LRRC52 IGFALS PXDN TLR3 PKD1 GP5

1.61e-04981546IPR000372
DomainLRRNT

LRRC52 IGFALS PXDN TLR3 PKD1 GP5

1.61e-04981546SM00013
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DOCK3 KMT2B BCL2L11 MYCBP2 PIEZO1 SIPA1L3 KSR2 INTS1 OBSCN SREBF1 CUL9 PLXND1 ATG2A POM121C ARHGEF10L FAM83H PIAS4 JAK3 SCAP CELSR3 NISCH PKD1 SCN8A HELZ2 ZER1 DISP2 TNKS1BP1 TNPO3

2.05e-1311051602835748872
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ENOSF1 CDC42BPG NEDD4L NUMBL MYCBP2 FLVCR1 SIPA1L3 KSR2 FRMPD1 OBSCN LAMA3 SRCIN1 UBN2 LRP8 PIAS4 ABCG1 PXDN KCNQ5 SEMA3B UQCRC1 MAP2K3 CNOT1 MTARC1

3.72e-0714891602328611215
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PABIR1 CARMIL2 NEDD4L NUMBL MYCBP2 SIPA1L3 ARHGEF17 FAM83H VPS13D MAP7D1 KCNQ5 ALMS1 SYNE2 DOCK7 TNKS1BP1 USP54 TNPO3

5.33e-078611601736931259
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

NEDD4L MYCBP2 PIEZO1 SREBF1 NCSTN PLXND1 NCAPG2 LRP8 GJA1 CNNM3 PDF SCAP PXDN CELSR3 SEMA3B TNKS1BP1 CERS1 MTARC1 SORL1

2.99e-0612011601935696571
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK3 SIPA1L3 UBN2 POM121C SHANK3 FAN1 VPS13D TTBK1 SCAP ALMS1 HELZ2 DISP3

3.34e-064931601215368895
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TBRG4 PIEZO1 SRCIN1 NCSTN PLXND1 ATG2A ARHGEF10L UBXN4 CELSR3 TNKS1BP1 CACNA1G CNOT1

6.81e-065291601214621295
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TBRG4 FRMPD1 FAN1 NISCH SYNE2 CNOT1

8.07e-06102160610231032
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CDC42BPG CYP26B1 KMT2B INTS1 OBSCN PTGER1 ARHGEF17 DARS2 SPATC1 TLR3 PKD1 SCN8A CNOT1 GP5

8.58e-067361601429676528
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYCBP2 SIPA1L3 SCAP ALMS1 SYNE2 HELZ2 TNKS1BP1 CACNA1G

1.04e-05225160812168954
Pubmed

Replication study of candidate genes for cognitive abilities: the Lothian Birth Cohort 1936.

NCSTN SHANK3 SORL1

1.12e-0510160319077115
Pubmed

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

CYP26B1 CYP3A43 CYP17A1 CYP4F2 CYP4F3

1.84e-0570160515128046
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NEDD4L TSPOAP1 FRMPD1 CUL9 ARHGEF17 MAP7D1 PXDN NISCH DOCK7 DISP2

2.07e-054071601012693553
Pubmed

Loss of apolipoprotein E receptor LR11 in Alzheimer disease.

LRP8 SORL1

2.10e-052160215313836
Pubmed

Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells.

NCSTN NOTCH4

2.10e-052160224919951
Pubmed

Wheel Running Improves Motor Function and Spinal Cord Plasticity in Mice With Genetic Absence of the Corticospinal Tract.

CELSR3 EMX1

2.10e-052160230941019
Pubmed

Association study between the TNXB locus and schizophrenia in a Japanese population.

TNXB NOTCH4

2.10e-052160217192952
Pubmed

DNA methylation of lipid-related genes affects blood lipid levels.

SREBF1 ABCG1

2.10e-052160225583993
Pubmed

Cyclic adenosine 5'-monophosphate-dependent sphingosine-1-phosphate biosynthesis induces human CYP17 gene transcription by activating cleavage of sterol regulatory element binding protein 1.

CYP17A1 SREBF1

2.10e-052160216306078
Pubmed

Isomer specific effects of Conjugated Linoleic Acid on macrophage ABCG1 transcription by a SREBP-1c dependent mechanism.

SREBF1 ABCG1

2.10e-052160217141191
Pubmed

Functional motor recovery from motoneuron axotomy is compromised in mice with defective corticospinal projections.

CELSR3 EMX1

2.10e-052160225003601
Pubmed

Lipogenic SREBP-1a/c transcription factors activate expression of the iron regulator hepcidin, revealing cross-talk between lipid and iron metabolisms.

SREBF1 SCAP

2.10e-052160231270208
Pubmed

Perilipin-mediated lipid droplet formation in adipocytes promotes sterol regulatory element-binding protein-1 processing and triacylglyceride accumulation.

SREBF1 PLIN1

2.10e-052160223734208
Pubmed

Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development.

DPY19L2 DPY19L2P2

2.10e-052160225354700
Pubmed

Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation.

DPY19L2 DPY19L2P2

2.10e-052160225354701
Pubmed

Nonalcoholic fatty liver disease impairs the cytochrome P-450-dependent metabolism of α-tocopherol (vitamin E).

SREBF1 CYP4F2

2.10e-052160228628909
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

2.10e-05216028026587
Pubmed

Association between SCAP and SREBF1 gene polymorphisms and metabolic syndrome in schizophrenia patients treated with atypical antipsychotics.

SREBF1 SCAP

2.10e-052160226982812
Pubmed

Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia.

SREBF1 SCAP

2.10e-052160217666524
Pubmed

Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus.

DPY19L2 DPY19L2P2

2.10e-052160222764053
Pubmed

Plasticity of motor network and function in the absence of corticospinal projection.

CELSR3 EMX1

2.10e-052160225792481
Pubmed

Shank3 Exons 14-16 Deletion in Glutamatergic Neurons Leads to Social and Repetitive Behavioral Deficits Associated With Increased Cortical Layer 2/3 Neuronal Excitability.

SHANK3 EMX1

2.10e-052160231649512
Pubmed

Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1.

ANKZF1 ZNF169

2.10e-052160238666541
Pubmed

The Role of SCAP/SREBP as Central Regulators of Lipid Metabolism in Hepatic Steatosis.

SREBF1 SCAP

2.10e-052160238256181
Pubmed

Cholesterol attenuated the progression of DEN-induced hepatocellular carcinoma via inhibiting SCAP mediated fatty acid de novo synthesis.

SREBF1 SCAP

2.10e-052160230638930
Pubmed

Sterol regulatory element binding protein and dietary lipid regulation of fatty acid synthesis in the mammary epithelium.

SREBF1 SCAP

2.10e-052160220739508
Pubmed

Congenital absence of corticospinal tract does not severely affect plastic changes of the developing postnatal spinal cord.

CELSR3 EMX1

2.10e-052160226079333
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

MCF2L2 CUL9 PLXND1 VPS13D CELSR3 ALMS1

3.22e-05130160612421765
Pubmed

Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo.

PLXND1 EMILIN1 PKD1

3.35e-0514160331475747
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

TBRG4 RNF31 MYCBP2 NADK2 UBN2 ANKZF1 ZER1 TNKS1BP1 UQCRC1 CNOT1 TNPO3

3.94e-055331601125544563
Pubmed

Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity.

NEDD4L GJA1

6.29e-053160238032389
Pubmed

Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.

CYP4F2 CYP4F3

6.29e-053160215145985
Pubmed

PlexinD1 and Sema3E determine laminar positioning of heterotopically projecting callosal neurons.

PLXND1 EMX1

6.29e-053160231454665
Pubmed

Synergy of TRIF-dependent TLR3 and MyD88-dependent TLR7 in up-regulating expression of mouse FPR2, a promiscuous G-protein-coupled receptor, in microglial cells.

FPR2 TLR3

6.29e-053160219559490
Pubmed

Prominent role of forebrain excitatory neurons in SCN8A encephalopathy.

SCN8A EMX1

6.29e-053160230601941
Pubmed

Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP.

SREBF1 SCAP

6.29e-053160227866836
Pubmed

Duplication and relocation of the functional DPY19L2 gene within low copy repeats.

DPY19L2 DPY19L2P2

6.29e-053160216526957
Pubmed

Correction of the hypomorphic Gabra2 splice site variant in mouse strain C57BL/6J modifies the severity of Scn8a encephalopathy.

SCN8A EMX1

6.29e-053160235047853
Pubmed

Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse.

SCN8A EMX1

6.29e-053160233140451
Pubmed

Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth.

SREBF1 SCAP

6.29e-053160226555173
Pubmed

Hedgehog signaling pathway and gastric cancer.

DISP3 DISP2

6.29e-053160216258256
Pubmed

Dynamics of Sun5 localization during spermatogenesis in wild type and Dpy19l2 knock-out mice indicates that Sun5 is not involved in acrosome attachment to the nuclear envelope.

DPY19L2 DPY19L2P2

6.29e-053160225775128
Pubmed

Association of MARC1, ADCY5, and BCO1 Variants with the Lipid Profile, Suggests an Additive Effect for Hypertriglyceridemia in Mexican Adult Men.

BCO1 MTARC1

6.29e-053160236233117
Pubmed

Phosphodiesterase 4B mediates extracellular signal-regulated kinase-dependent up-regulation of mucin MUC5AC protein by Streptococcus pneumoniae by inhibiting cAMP-protein kinase A-dependent MKP-1 phosphatase pathway.

PDE4B MUC5AC

6.29e-053160222610099
Pubmed

Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes.

SREBF1 SCAP

6.29e-053160214512514
Pubmed

Cigarette smoke augments MUC5AC production via the TLR3-EGFR pathway in airway epithelial cells.

TLR3 MUC5AC

6.29e-053160226100173
Pubmed

Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating protein.

SREBF1 SCAP

6.29e-05316029242699
Pubmed

DNA methylome analysis identifies BMI-related epigenetic changes associated with non-small cell lung cancer susceptibility.

SREBF1 ABCG1

6.29e-053160233939316
Pubmed

GP73 regulates Hepatic Steatosis by enhancing SCAP-SREBPs interaction.

SREBF1 SCAP

6.29e-053160229097707
Pubmed

Loss of PKD1 and loss of Bcl-2 elicit polycystic kidney disease through distinct mechanisms.

BCL2L11 PKD1

6.29e-053160216282979
Pubmed

Unbiased proteomic screening identifies a novel role for the E3 ubiquitin ligase Nedd4-2 in translational suppression during ER stress.

NEDD4L EMX1

6.29e-053160233064840
Pubmed

PIASy-mediated sumoylation of SREBP1c regulates hepatic lipid metabolism upon fasting signaling.

SREBF1 PIAS4

6.29e-053160224379443
Pubmed

Rhinovirus-induced major airway mucin production involves a novel TLR3-EGFR-dependent pathway.

TLR3 MUC5AC

6.29e-053160218978302
Pubmed

Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity.

SREBF1 SCAP

6.29e-053160223563690
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

NEDD4L RNF31 TMEM199 ATG2A DARS2 CNNM3 UBXN4 SCAP SYNE2 CERS1

6.68e-054681601031056421
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

NUDT19 ENOSF1 TBRG4 BCL2L11 PDK4 NADK2 FASTKD1 CLPX LAP3 DARS2 PDF VPS13D NCBP2AS2 UQCRC1 MTO1 MTARC1

7.54e-0511361601634800366
Pubmed

Genome-wide identification of FOXL2 binding and characterization of FOXL2 feminizing action in the fetal gonads.

CYP26B1 CYP17A1 SRY

8.77e-0519160330212841
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

ISYNA1 OBSCN SRCIN1 DOCK7 ZER1 TNKS1BP1 MAP2K3 CNOT1

8.79e-05304160832235678
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DOCK3 MYCBP2 TAF1C SIPA1L3 MCF2L2 CUL9 NCKAP5 HUNK ZBED5 FAN1 SYNGAP1 CELSR3 NISCH PKD1 DENND6B UQCRC1 USP54

9.55e-0512851601735914814
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

MYCBP2 FAM83H ALMS1 DOCK7 USP54

1.07e-04101160524613305
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

ANKZF1 SHANK3 MAP7D1 KCNQ5 ALMS1 GUCY1A2 NOTCH4

1.08e-04233160737704626
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SRCIN1 HELZ2 DOCK7 DISP2 TNKS1BP1

1.13e-04102160511214970
Pubmed

Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

TNXB TNPO3 NOTCH4

1.20e-0421160321408207
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

ISYNA1 MYCBP2 MARCHF7 DARS2 FAM83H VPS13D MAP7D1 USP54 MTO1 MAP2K3 MTARC1

1.23e-046061601136538041
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

TBRG4 FLVCR1 MARCHF7 NCSTN POM121C NCAPG2 DARS2 GJA1 CNNM3 SCAP PXDN NISCH CERS1 TNPO3

1.24e-049421601431073040
Pubmed

Syngap1 Disruption Induced by Recombination between Inverted loxP Sites Is Associated with Hippocampal Interneuron Dysfunction.

SYNGAP1 EMX1

1.25e-044160237072176
Pubmed

C2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms.

NEDD4L EMX1

1.25e-044160231357244
Pubmed

Insulin regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes: roles of forkhead box O1 and sterol regulatory element-binding protein 1c.

CYP17A1 SREBF1

1.25e-044160216885156
Pubmed

Association of selected ABC gene family single nucleotide polymorphisms with postprandial lipoproteins: results from the population-based Hortega study.

ABCG1 ABCG8

1.25e-044160220170916
Pubmed

An mRNA differential display strategy for cloning genes expressed during mouse gonad development.

CYP17A1 SRY

1.25e-04416029303351
Pubmed

Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR.

ABCG1 ABCG8

1.25e-044160212777468
Pubmed

Circadian lipid synthesis in brown fat maintains murine body temperature during chronic cold.

SREBF1 SCAP

1.25e-044160231451658
Pubmed

Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice.

SREBF1 SCAP

1.25e-044160228244871
Pubmed

Srebp-controlled glucose metabolism is essential for NK cell functional responses.

SREBF1 SCAP

1.25e-044160228920951
Pubmed

SREBP-1a-stimulated lipid synthesis is required for macrophage phagocytosis downstream of TLR4-directed mTORC1.

SREBF1 SCAP

1.25e-044160230530672
Pubmed

Role of ABCG1 and other ABCG family members in lipid metabolism.

ABCG1 ABCG8

1.25e-044160211590207
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3

1.25e-044160218065749
Pubmed

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.

SREBF1 SCAP

1.25e-044160212202038
Pubmed

Somatostatin-Positive Interneurons Contribute to Seizures in SCN8A Epileptic Encephalopathy.

SCN8A EMX1

1.25e-044160234544834
Pubmed

Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia.

NEDD4L EMX1

1.25e-044160222213801
Pubmed

FASTKD1 and FASTKD4 have opposite effects on expression of specific mitochondrial RNAs, depending upon their endonuclease-like RAP domain.

TBRG4 FASTKD1

1.25e-044160228335001
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

DOCK3 KMT2B CUL9 CYP4F2 NCKAP5 SHANK3 CELSR3 PKD1

1.51e-04329160817474147
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

PDE4B NEDD4L NUMBL MYCBP2 SIPA1L3 KSR2 UBN2 SHANK3 SYNGAP1 MAP7D1 NISCH SYNE2 DOCK7 CNOT1

1.56e-049631601428671696
Pubmed

Genomic variants in an inbred mouse model predict mania-like behaviors.

KSR2 OBSCN CP

1.58e-0423160329768498
Pubmed

Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).

BCL2L11 OBSCN NCSTN ARHGEF17

1.72e-0460160412787561
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

DDX49 KMT2B NUMBL PIEZO1 TAF1C SIPA1L3 INTS1 DHX33 UBN2 ANKZF1 INTS10 MAP7D1 UBXN4 PXDN KCTD3 HELZ2 UQCRC1 IMP3

1.94e-0414971601831527615
Pubmed

A hearing and vestibular phenotyping pipeline to identify mouse mutants with hearing impairment.

NISCH SCN8A

2.08e-045160220057387
Pubmed

Upregulation of SYNGAP1 expression in mice and human neurons by redirecting alternative splicing.

SYNGAP1 EMX1

2.08e-045160236917980
Pubmed

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins.

SREBF1 SCAP

2.08e-045160212242332
Pubmed

Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism.

CYP4F2 CYP4F3

2.08e-045160218577768
Pubmed

Endoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cells.

SREBF1 SCAP

2.08e-045160222690709
InteractionTOP3B interactions

NUDT19 DOCK3 KMT2B BCL2L11 MYCBP2 PIEZO1 SIPA1L3 KSR2 INTS1 OBSCN SREBF1 CUL9 PLXND1 ATG2A CLPX POM121C ARHGEF10L FAM83H PIAS4 JAK3 SCAP CELSR3 NISCH PKD1 SCN8A HELZ2 ZER1 DISP2 TNKS1BP1 CNOT1 TNPO3

3.05e-07147015731int:TOP3B
GeneFamilyBlood group antigens|CD molecules|ATP binding cassette subfamily G

ABCG1 ABCG8

2.88e-045982811
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

MCF2L2 OBSCN ARHGEF17 ARHGEF10L

4.52e-0466984722
GeneFamilySodium voltage-gated channel alpha subunits

SCN4A SCN8A

1.02e-0399821203
GeneFamilyFibronectin type III domain containing

NPHS1 TSPOAP1 OBSCN TNXB SORL1

1.79e-03160985555
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TSPOAP1 PIEZO1 MCF2L2 INTS1 ZNF169 ABCG1 ADRA2B TMEM37

1.27e-0716116082fe77af3b41e6eacb707a64feea18f9991618173
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP26B1 PIWIL1 PLXND1 SHANK3 TMTC1 ABCG1 TNXB NOTCH4

5.27e-071941608ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PDE4B PLXND1 SHANK3 GJA1 TMTC1 ABCG1 PXDN NOTCH4

5.70e-071961608b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCellTracheal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ISYNA1 DPY19L2 NCKAP5 PLXND1 PTGER1 ARHGEF17 ADRA2B GUCY1A2

6.63e-0720016089d3ae9ea47b1017adb63aa02d10e98193d478458
ToppCellTracheal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ISYNA1 DPY19L2 NCKAP5 PLXND1 PTGER1 ARHGEF17 ADRA2B GUCY1A2

6.63e-07200160878cd0b7d221ef855512ee9ac9a291f61622c2e24
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

GPR34 PIEZO1 MCF2L2 INTS1 ZNF169 ABCG1 ADRA2B

1.51e-06155160715bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHS1 NUMBL GPR34 ITGAL ABCG1 TTBK1 CD27

1.86e-061601607398f162e8a75c6cb5c3e4d1832e98d386e1f222b
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHS1 NUMBL GPR34 ITGAL ABCG1 TTBK1 CD27

1.86e-06160160712aaab0291035f578e2433efd169ae72f393a5a5
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBM44 HIRIP3 MYCBP2 FPR2 LRP8 ABCG1 CELSR3

2.90e-061711607845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 NPHS1 KSR2 LAMA3 DISP3 CERS1

2.91e-061101606c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|343B / Donor, Lineage, Cell class and subclass (all cells)

THEMIS FLVCR1 UBN2 POM121C CD27 DENND6B C8orf76

3.78e-061781607ec6364432d37a32f5152d36d89f5e96dddb72a9d
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OBSCN ITGA10 ARHGEF17 EMILIN1 GJA1 PXDN GUCY1A2

3.92e-061791607a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK3 JPH4 MCF2L2 SRCIN1 LRP8 KCNQ5 DISP3

4.37e-061821607be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR39 LAMA3 CP SYNE2 SEMA3B TNKS1BP1 USP54

4.70e-06184160742ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SIPA1L3 LAMA3 CP SYNE2 SEMA3B TNKS1BP1 USP54

5.23e-06187160758d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellCOVID-19-T_cells|COVID-19 / group, cell type (main and fine annotations)

KLF12 THEMIS ITGAL JAK3 KCNQ5 SYNE2 SORL1

6.00e-0619116077f64add931b64b8d35836fa6bee9ebab593844d3
ToppCellhuman_hepatoblastoma-Endothelial_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

PLXND1 SHANK3 GJA1 TMTC1 ABCG1 PXDN NOTCH4

6.21e-061921607e09f609fed033a25baacaf4a07bbbae1076da366
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIWIL1 PLXND1 SHANK3 TMTC1 ABCG1 TNXB NOTCH4

6.65e-061941607cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

CP SHANK3 GJA1 TMTC1 ABCG1 TNXB NOTCH4

7.59e-0619816078689090bce9ab6e8f122426a404037e572c6713b
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DOCK3 CDC42BPG SERPINA3 ADRA2B KCTD3 CACNA1G

9.47e-061351606c4d3c9eba2a85ac40fea5ecfcc2b442a472323d0
ToppCellBL-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MCIDAS LAMA3 CP HUNK DISP3 CDCA7L

2.48e-0516016063f737451d5713deed20061aa72a9ef77a9a2bc06
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 JPH4 GPR34 FAN1 TMEM37 RD3

2.57e-051611606334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 JPH4 GPR34 FAN1 TMEM37 RD3

2.57e-05161160681d44438e4be4e68a59247e62f02026301a8a0c5
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

GPR34 PDK4 GPR39 PLXND1 NISCH TMEM37

2.76e-0516316064b8abbad4df040c895e3afb240759ebbc66b4d0e
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

PDE4B CYP26B1 TSPOAP1 SHANK3 TLR3 RD3

2.76e-051631606d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_2|Striatum / BrainAtlas - Mouse McCarroll V32

PIWIL1 ITGAL FAM83H CD27 PLIN1

2.78e-059816057a62a77ca83153dacff4d02d6e32104227d0980d
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocye.Tnr.Pdgfa_(Pdgfa)|Striatum / BrainAtlas - Mouse McCarroll V32

PIWIL1 ITGAL FAM83H CD27 PLIN1

2.78e-0598160526250ea4171a0557a67505839cf79d3fe4d9d41a
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr|Striatum / BrainAtlas - Mouse McCarroll V32

PIWIL1 ITGAL FAM83H CD27 PLIN1

2.78e-0598160542875d16ae9fcbaf988cd71be82568f2f862f2dd
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THEMIS HIRIP3 BCL2L11 CUL9 PIAS4 KCNQ5

2.95e-0516516068c7a6f9e2ca0ce077426d3d0726e3f5a4c03b296
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NEDD4L GPR39 NCKAP5 SRCIN1 SYNE2 USP54

3.49e-051701606a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

NPHS1 GPR34 PDK4 ADRA2B MAP2K3 MUC5AC

3.73e-051721606f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIWIL1 SHANK3 TMTC1 ABCG1 DISP3 NOTCH4

3.73e-051721606c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LVRN MCF2L2 PLXND1 SHANK3 TMTC1 NOTCH4

3.98e-0517416063d4c05ea5719ca65e85d1f15198453034791087c
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)-|367C / Donor, Lineage, Cell class and subclass (all cells)

NEDD4L GPR39 LAMA3 NCKAP5 CELSR3 USP54

3.98e-051741606edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)|367C / Donor, Lineage, Cell class and subclass (all cells)

NEDD4L GPR39 LAMA3 NCKAP5 CELSR3 USP54

3.98e-05174160665539f69100db0b7d90b1b39ee15ab8281f86461
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 PIWIL1 PLXND1 SHANK3 TNXB NOTCH4

4.10e-05175160690302e8a44858ef3b2a165b88284d4788d591a99
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYOZ2 HUNK ARHGEF17 KCNQ5 GUCY1A2 TNKS1BP1

4.10e-0517516062a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYOZ2 HUNK ARHGEF17 KCNQ5 GUCY1A2 TNKS1BP1

4.10e-051751606fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT19 CP LAP3 MEP1A IGFALS TMEM37

4.10e-051751606076ad81d6cbeea5512393d192af3ab5aa1f82975
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT19 CP LAP3 MEP1A IGFALS TMEM37

4.10e-051751606445ccb9744a3a9ff37164c532afbe769d306b6c8
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLF12 THEMIS CARMIL2 ABCG1 KCNQ5 SORL1

4.24e-051761606ea27e18407b8a13e8212830da859efeb8f158690
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLF12 THEMIS CARMIL2 ABCG1 KCNQ5 SORL1

4.24e-051761606bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

NEDD4L GPR39 LAMA3 NCKAP5 SEMA3B USP54

4.66e-051791606a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Activated_fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CYP26B1 FPR2 SREBF1 ITGAL PIAS4 ZER1

4.66e-0517916065787ffba96918db80256ced076a455a84ba01384
ToppCellfacs-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOZ2 HUNK ARHGEF17 KCNQ5 GUCY1A2 TNKS1BP1

4.66e-0517916067078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCellfacs-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOZ2 HUNK ARHGEF17 KCNQ5 GUCY1A2 TNKS1BP1

4.66e-051791606d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCellLPS_only-Lymphocytic_NKT-T_cells-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLF12 THEMIS CARMIL2 ABCG1 KCNQ5 SORL1

4.80e-051801606dcef253f2e97e4436b1b04e8a06a53ff6e64522c
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLXND1 SHANK3 LAP3 ABCG1 PXDN HELZ2

4.80e-051801606d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

NEDD4L NCKAP5 SHANK3 PXDN SYNE2 NOTCH4

4.95e-051811606c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellLPS_only-Lymphocytic_NKT-T_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLF12 THEMIS CARMIL2 ABCG1 KCNQ5 SORL1

4.95e-051811606a4347ae554e6dcf03c7001a2b69332b377c7c034
ToppCellHealthy_donor-MAIT|Healthy_donor / disease group, cell group and cell class (v2)

PDE4B THEMIS DPY19L2 ATG2A CD27 SYNE2

5.11e-051821606ac7c83464487ecde3df6804a99551307bd768f21
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DPY19L2 GPR39 KSR2 HUNK DOCK7 EMX1

5.11e-051821606f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCellCOPD-Epithelial-ATI|World / Disease state, Lineage and Cell class

NEDD4L GPR39 LAMA3 NCKAP5 GJA1 SEMA3B

5.11e-051821606e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

PDE4B CYP26B1 SHANK3 ABCG1 HELZ2 NOTCH4

5.11e-051821606fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

ISYNA1 ARHGEF17 TMTC1 VPS13D ADRA2B GUCY1A2

5.26e-051831606273db6a3b00a93ca852498471187b642b5368185
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PIEZO1 LAMA3 NCKAP5 GJA1 MAP7D1 SEMA3B

5.43e-051841606c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PIEZO1 LAMA3 NCKAP5 GJA1 MAP7D1 SEMA3B

5.43e-0518416061ed558a88215b248431c524ea16f13d9022ae98c
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP5 ARHGEF17 BCO1 ADRA2B DISP2 TNXB

5.59e-051851606f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP5 ARHGEF17 BCO1 ADRA2B DISP2 TNXB

5.59e-05185160640e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP5 ARHGEF17 BCO1 ADRA2B DISP2 TNXB

5.59e-0518516065f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellCOPD-Epithelial-ATI|COPD / Disease state, Lineage and Cell class

NEDD4L GPR39 LAMA3 NCKAP5 GJA1 SEMA3B

5.76e-051861606df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCell5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THEMIS CARMIL2 ITGAL JAK3 CD27 GP5

5.93e-051871606c0a18ab7d88420e20e478ccdce6a2cb0a60a7824
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NEDD4L GPR39 LAMA3 NCKAP5 SEMA3B USP54

5.93e-0518716064ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THEMIS CARMIL2 ITGAL JAK3 CD27 GP5

5.93e-051871606442b7bf6bc17fc2d38bccd678be8994b0ead374f
ToppCell5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THEMIS CARMIL2 ITGAL JAK3 CD27 GP5

5.93e-051871606fda45c15806f34e45d44bb2e1d144591bc6eaa02
ToppCellP15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ISYNA1 PDE4B PLXND1 CDCA7L NOTCH4 GP5

6.11e-05188160650b27fc12347ca16bd62333baf345c83cb422a8f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NEDD4L GPR39 LAMA3 NCKAP5 SEMA3B USP54

6.11e-051881606eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellwk_08-11-Mesenchymal-Mesothelial-Early_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NPHS1 ISYNA1 CYP17A1 LRP8 GJA1 TMEM37

6.11e-0518816066151051c027c7ff7d5d4bf5f1e11d7fe58eb22ed
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OBSCN ITGA10 EMILIN1 GJA1 PXDN CACNA1G

6.11e-051881606997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellfacs-Skin-Telogen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4B FLVCR1 GJA1 ABCG1 MAP2K3 TNXB

6.11e-0518816068cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCellControl-Epithelial_alveolar-Mes-Like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CYP26B1 KSR2 LAMA3 DHX33 SPATC1

6.23e-051161605df7609503782d8d7e4f31ed2a626916e5474d5bc
ToppCellCOVID-19-T_cells-CD8+_T_cells|COVID-19 / group, cell type (main and fine annotations)

KLF12 THEMIS ITGAL JAK3 KCNQ5 SYNE2

6.29e-0518916062c018d6120f65f0b2704b483bc9da1c0984872e3
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

ISYNA1 ARHGEF17 ADRA2B GUCY1A2 SYNE2 NOTCH4

6.29e-0518916069c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDK4 KSR2 PTGER1 ARHGEF10L DOCK7 EMX1

6.29e-051891606c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

DPY19L2 PDK4 OBSCN MYOZ2 NCKAP5 USP54

6.29e-0518916060a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP26B1 PIEZO1 LAMA3 PLXND1 SHANK3 NOTCH4

6.48e-051901606b7fc451e160e31dc898b122de844b501f587db67
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CARMIL2 MYCBP2 TSPOAP1 KSR2 CELSR3 SCN8A

6.48e-051901606416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell21-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

PLXND1 EMILIN1 SHANK3 PXDN TMEM37 NOTCH4

6.48e-051901606bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NEDD4L GPR39 LAMA3 NCKAP5 SEMA3B USP54

6.48e-05190160630b50d183d7649146eb1e79b47ba897355f1998a
ToppCellhuman_hepatoblastoma-Endothelial_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

SHANK3 GJA1 TMTC1 ABCG1 PXDN NOTCH4

6.48e-0519016068d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

ARHGEF17 SHANK3 TMTC1 GUCY1A2 SYNE2 NOTCH4

6.48e-051901606a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP26B1 PIEZO1 LAMA3 PLXND1 SHANK3 NOTCH4

6.48e-05190160683cc851fb9f644b17a8ebf4d99a646003769a22f
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP26B1 PIEZO1 LAMA3 PLXND1 SHANK3 NOTCH4

6.48e-0519016065f440d4b334d66d419c03bd828f7d93f16c1ce67
ToppCell21-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

PLXND1 EMILIN1 SHANK3 PXDN TMEM37 NOTCH4

6.48e-05190160608437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

KLF12 NUDT17 ZBED5 ZER1 CNOT1 TNPO3

6.67e-051911606d7920f4a602b50d0ef064eb47001e71939695ed2
ToppCellAdult-Immune-natural_killer_cell|Adult / Lineage, Cell type, age group and donor

KLF12 ITGAL JAK3 KCNQ5 SYNE2 SORL1

6.67e-051911606758ec27e47d7662a5175305e98a1506c6859dbf7
ToppCellCOVID-19-T_cells-CD4+_T_cells|COVID-19 / group, cell type (main and fine annotations)

KLF12 THEMIS ITGAL JAK3 SYNE2 SORL1

6.67e-0519116060646cca78e24aeb6baa9934d3c439b797c567997
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CP SHANK3 TMTC1 ABCG1 SYNE2 NOTCH4

6.87e-05192160627ff3621e177e7932dd44dd6baa81551ea75a874
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

DOCK3 DPY19L2 PDK4 OBSCN MYOZ2 NCKAP5

6.87e-051921606ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA10 LAMA3 CP SHANK3 TMTC1 NOTCH4

6.87e-0519216063259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCellAT1_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

NEDD4L LAMA3 NCKAP5 GJA1 PXDN SEMA3B

6.87e-0519216060444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 DPY19L2 PDK4 OBSCN MYOZ2 NCKAP5

7.07e-051931606dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CYP26B1 PLXND1 SHANK3 TMTC1 TNXB NOTCH4

7.07e-0519316061f978e102a029a6beb10913052cd0a20c7253e8e
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PDE4B SHANK3 GJA1 ABCG1 PXDN NOTCH4

7.07e-051931606479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EMILIN1 JAK3 TMTC1 PXDN GUCY1A2 TNXB

7.27e-05194160681713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellIPF-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

ISYNA1 DPY19L2 NCKAP5 ARHGEF17 GUCY1A2 SYNE2

7.27e-0519416063892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCellEndothelial-A-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

CYP26B1 SHANK3 TMTC1 ADRA2B TNXB NOTCH4

7.27e-051941606e656ac5539e59e321b46706cb8cc423b2c3358a0
ToppCellIPF-Endothelial-VE_Capillary_B|IPF / Disease state, Lineage and Cell class

ITGA10 NCKAP5 SHANK3 TMTC1 PXDN NOTCH4

7.27e-051941606169a304d5c13f08c39fad4116f093bc4a0765e9d
ToppCellIPF-Endothelial|IPF / Disease state, Lineage and Cell class

ITGA10 SHANK3 GJA1 TMTC1 PXDN NOTCH4

7.27e-0519416069591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

PIEZO1 LAMA3 NCKAP5 SEMA3B CDCA7L FHIP2B

7.27e-05194160688db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
Diseasearthritis

SHANK3 BCO1

8.09e-0531542EFO_0005856
Diseasemetabolite measurement

CYP3A43 PIWIL1 SREBF1 CYP4F2 CAPN11 BCO1 ALMS1 SYNE2 DPY19L2P2 ABCG8 SORL1

1.82e-0456015411EFO_0004725
Diseasehippurate measurement

ABCG1 MAP2K3

2.68e-0451542EFO_0010992
DiseasePR interval

MYCBP2 SYNPO2L OBSCN MYOZ2 CUL9 NCKAP5 CSHL1 SYNE2 CACNA1G CNOT1

2.88e-0449515410EFO_0004462
Diseasemyeloperoxidase measurement

TSPOAP1 TNXB NOTCH4

3.32e-04261543EFO_0005243
DiseaseLiver carcinoma

KMT2B PDK4 CYP17A1 FLVCR1 SREBF1 CP ADRA2B SCAP IGFALS CELSR3

3.48e-0450715410C2239176
Diseasetongue squamous cell carcinoma (biomarker_via_orthology)

JAK3 GJA1

4.00e-0461542DOID:0050865 (biomarker_via_orthology)
Diseasecholesterol to total lipids in very small VLDL percentage

INTS10 DOCK7 ABCG8 MTARC1

4.24e-04671544EFO_0022245
Diseaseheart failure

PDE4B NEDD4L SYNPO2L POM121C TMTC1 PKD1

4.37e-041851546EFO_0003144
DiseaseEpileptic encephalopathy

NEDD4L SYNGAP1 KCTD3

5.10e-04301543C0543888
Diseasecholesteryl esters to total lipids in very small VLDL percentage

INTS10 DOCK7 ABCG8 MTARC1

5.28e-04711544EFO_0022259
DiseaseProfound Mental Retardation

SHANK3 SYNGAP1 ADRA2B SCN8A CACNA1G

8.32e-041391545C0020796
DiseaseMental Retardation, Psychosocial

SHANK3 SYNGAP1 ADRA2B SCN8A CACNA1G

8.32e-041391545C0025363
DiseaseMental deficiency

SHANK3 SYNGAP1 ADRA2B SCN8A CACNA1G

8.32e-041391545C0917816
Diseaseobesity (implicated_via_orthology)

DHX33 PLXND1 CAPN11 ALMS1 PLIN1 NOTCH4

9.58e-042151546DOID:9970 (implicated_via_orthology)
Diseasethioredoxin domain-containing protein 12 measurement

DOCK3 SCAP CELSR3

1.11e-03391543EFO_0008298
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

INTS10 SYNE2 HELZ2 DOCK7 ABCG8 MTARC1

1.13e-032221546EFO_0008317, EFO_0020943
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

INTS10 SYNE2 DOCK7 ABCG8 MTARC1

1.17e-031501545EFO_0004611, EFO_0020947
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN4A SCN8A

1.18e-03101542DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN4A SCN8A

1.18e-03101542DOID:0080422 (implicated_via_orthology)
Diseaseubiquitin-conjugating enzyme E2 G2 measurement

TNXB NOTCH4

1.18e-03101542EFO_0022035
Diseasehypertrophic cardiomyopathy

SYNPO2L NCKAP5 PKD1 TNKS1BP1

1.40e-03921544EFO_0000538
Diseasepeptidyl-glycine alpha-amidating monooxygenase measurement

LVRN MYCBP2

1.44e-03111542EFO_0801871
Diseaseleft ventricular systolic function measurement

NEDD4L OBSCN PXDN

1.58e-03441543EFO_0008206
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN4A SCN8A

1.73e-03121542DOID:0060170 (implicated_via_orthology)
Diseasemethionine sulfone measurement

CYP3A43 ALMS1

1.73e-03121542EFO_0800072
Diseasedementia (is_implicated_in)

LRP8 NOTCH4

1.73e-03121542DOID:1307 (is_implicated_in)
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

DOCK7 ZER1 ABCG8 MTARC1

1.83e-03991544EFO_0004611, EFO_0007878
DiseaseJT interval

KLF12 PDE4B OBSCN CNNM3 PXDN CNOT1

1.98e-032481546EFO_0007885
Diseasehematologic cancer (implicated_via_orthology)

PIAS4 JAK3

2.03e-03131542DOID:2531 (implicated_via_orthology)
Diseasemiddle temporal gyrus volume measurement, Alzheimer's disease biomarker measurement

MYCBP2 KSR2

2.03e-03131542EFO_0006514, EFO_0010316
DiseaseQT interval

KLF12 PDE4B SYNPO2L MCF2L2 CNNM3 SCAP PXDN CNOT1 NOTCH4

2.04e-035341549EFO_0004682
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

DOCK7 ZER1 ABCG8 MTARC1

2.04e-031021544EFO_0004329, EFO_0004611
Diseaseinsomnia measurement

PDE4B NEDD4L MYCBP2 KSR2 MARCHF7 ARHGEF10L ALMS1 SORL1

2.35e-034431548EFO_0007876
Diseasegastric ulcer (implicated_via_orthology)

PTGER1 MUC5AC

2.36e-03141542DOID:10808 (implicated_via_orthology)
Diseasedystonia (is_implicated_in)

KMT2B TSPOAP1

2.36e-03141542DOID:543 (is_implicated_in)
DiseaseAutistic Disorder

PDE4B TAF1C CP SHANK3 SYNGAP1 GJA1

2.55e-032611546C0004352
Diseasephospholipids in IDL measurement

DOCK7 ABCG8 MTARC1

2.55e-03521543EFO_0022164
Diseasetotal phospholipids in lipoprotein particles measurement

DOCK7 ABCG8 MTARC1

2.70e-03531543EFO_0022315
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

INTS10 SYNE2 HELZ2 DOCK7 ABCG8 MTARC1

2.70e-032641546EFO_0008317, EFO_0020944
DiseaseN-acetylmethionine measurement

DOCK3 ALMS1

2.72e-03151542EFO_0021427
DiseaseTremor, Rubral

CP SCN8A

3.10e-03161542C0750940
DiseaseAtaxia, Appendicular

CP SCN8A

3.10e-03161542C0750937
DiseaseAtaxia, Motor

CP SCN8A

3.10e-03161542C0278161
Diseaseendoplasmic reticulum resident protein 29 measurement

TNXB NOTCH4

3.10e-03161542EFO_0020346
DiseaseAtaxia, Sensory

CP SCN8A

3.10e-03161542C0240991
DiseaseAbnormal coordination

CP SCN8A

3.10e-03161542C0520966
DiseaseAtaxia, Truncal

CP SCN8A

3.10e-03161542C0427190
Diseasecholesterol in medium HDL measurement

TMEM199 INTS10 MTARC1

3.66e-03591543EFO_0021903
Diseasephospholipids in VLDL measurement

INTS10 DOCK7 ABCG8

3.66e-03591543EFO_0022301
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

INTS10 SYNE2 ABCG8 MTARC1

3.78e-031211544EFO_0008595, EFO_0020943
Diseasetotal lipids in IDL

DOCK7 ABCG8 MTARC1

3.84e-03601543EFO_0022161
Diseasehuman papilloma virus infection

KLF12 GPR39

3.92e-03181542EFO_0001668
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

INTS10 SYNE2 HELZ2 DOCK7 ABCG8 MTARC1

4.35e-032911546EFO_0008317, EFO_0020946
DiseaseX-11470 measurement

TNXB NOTCH4

4.37e-03191542EFO_0021241
Diseasetriglycerides to total lipids in IDL percentage

DOCK7 ABCG8 MTARC1

4.40e-03631543EFO_0022329
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

INTS10 SYNE2 ABCG8 MTARC1

4.49e-031271544EFO_0008595, EFO_0020947
DiseaseObesity

CYP26B1 KSR2 SREBF1 ZNF169 PLIN1

4.52e-032051545C0028754
DiseaseAlzheimer's disease (is_implicated_in)

NCSTN LRP8 UQCRC1 SORL1

5.14e-031321544DOID:10652 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
RKSSRRIDRFTFPAL

ARHGEF10L

111

Q9HCE6
ILSLVFASRLRPASR

DISP3

741

Q9P2K9
TFNPTTSILLVRARE

ERVK13-1

241

Q9NX77
QTLADFRQLPARTLS

CD27

161

P26842
TQILQRAPLRSFTET

CLPX

46

O76031
FSSLPRRAAVNIEFR

ABCG1

66

P45844
LVETRTIVRFNRPFL

SERPINA3

386

P01011
PAALQLFLSRARTLR

CARMIL2

451

Q6F5E8
SGSLRPLDTFRVLSQ

EVX1

301

P49640
LLFRRFQGEPSRSES

GPR34

341

Q9UPC5
RDLLRPFVRATLQES

ALMS1

4026

Q8TCU4
SRLEPVRFLRSTFTN

CSHL1

116

Q14406
TLIRRQISNDFRDLP

ABCG8

401

Q9H221
RSPLFIFMRRSSLLS

BCL2L11

76

O43521
RLSHNAIASLRPRTF

IGFALS

296

P35858
AVLTSRSLRAPQNLF

ADRA2B

36

P18089
RRALLASQLEPTFAR

LVRN

231

Q6Q4G3
IFTNSREVSSQLRLP

CAPN11

501

Q9UMQ6
VSRLPFVRLFQALLS

DENND6B

156

Q8NEG7
LSRRFPRQLAFLLST

C3orf22

106

Q8N5N4
PDRLSRVAFSLRQTS

DISP2

1046

A7MBM2
QPRRSFFESFIRTLI

TMEM37

16

Q8WXS4
QTVFRLSAPRATLRL

ATG2A

631

Q2TAZ0
RLNELPSTLQRRTDF

NUMBL

326

Q9Y6R0
VALRRVLLAQFSAFP

RAD51D

51

O75771
QIHSEFSISRLPRTR

RBM44

931

Q6ZP01
RLEQRAATLQFTTLP

TSPOAP1

961

O95153
QRPSFRAVIRDLNSL

JAK3

766

P52333
TRFTFRTARQVPRLG

ISYNA1

46

Q9NPH2
TQFLRSLFETLPGRV

INTS10

96

Q9NVR2
SRDLPRIFRVTTSQL

CDC42BPG

1021

Q6DT37
VRSTARLARALSPAF

NCSTN

621

Q92542
RTSFAFLRQELPVRL

PDK4

51

Q16654
RSLSPSVRQLSRRFD

ARHGEF17

76

Q96PE2
ASFIRTRLLLQFTQP

C8orf76

266

Q96K31
RRDTANLFPQTSLTL

CP

671

P00450
GRPTRTLIEFLLRFS

LAP3

501

P28838
TARVTPRSSDNRQLL

NPHS1

201

O60500
PLLFASRRQSSARRT

GPR39

391

O43194
TRSFFRGRPDLSTLT

HIRIP3

11

Q9BW71
SSALARFVLLAQSRP

MTARC1

6

Q5VT66
IAIRERFNISTPAFR

LAMA3

2721

Q16787
RRPEILSFFSTNLQR

INTS1

2076

Q8N201
VQLLLSRRPESVSFA

NUDT17

6

P0C025
LTPFLRGTTRRFDTA

NUDT19

201

A8MXV4
PSVVRTEIFLQSSRR

SLC2A7

401

Q6PXP3
SIREPIANRVFSSSR

NADK2

376

Q4G0N4
FTSRVEFRLSLRPDN

MTO1

491

Q9Y2Z2
SSRPLRVLTAVVASF

FPR2

236

P25090
TSRFELATRTFPRIT

CYP26B1

461

Q9NR63
SFNDRTRFRPSLRLK

KCNQ5

466

Q9NR82
RSPLLSERSLRSFFV

KSR2

356

Q6VAB6
PATRSRITLVASALR

EZHIP

211

Q86X51
QAALLRSPRRTSLDS

JPH4

151

Q96JJ6
ISRLSVRDVRFPTSL

ENOSF1

6

Q7L5Y1
RPSRFIQRTFTDIGI

MCF2L2

136

Q86YR7
SRLVSVFPARERLFA

PLXND1

356

Q9Y4D7
RQLRSPALLREAVAF

FHIP2B

401

Q86V87
STSLQRPLFLAVRLA

PTGER1

326

P34995
VTPFAQVLASLRSVR

PDE4B

166

Q07343
RRLFLNENRITSLPA

LRRC52

56

Q8N7C0
DVAPSSLRSALRSQR

KMT2B

131

Q9UMN6
QLRRSQESAAPTLSR

MUC5AC

121

P98088
RRSSIGLRVAFQFPT

CDCA7L

136

Q96GN5
RFTTRRSQSPINCIR

PABIR1

181

Q96E09
ILRTSSNDRRPFIAL

DPY19L2

316

Q6NUT2
RVFVNPSLRVLDSRL

PDF

151

Q9HBH1
LLRTPALRSTATFAQ

UQCRC1

26

P31930
RIRSHSTIRTLAFPQ

MCIDAS

351

D6RGH6
DRRFSRSAIPEQIIS

POM121C

256

A8CG34
STRLRSARNSISVPI

PLIN1

121

O60240
RTSATLTIRALPARF

OBSCN

3526

Q5VST9
TSATLTVRALPARFI

OBSCN

3791

Q5VST9
FSFSESRRILLPVVL

DOCK3

846

Q8IZD9
RSAVRPASLNLNRSR

DOCK7

881

Q96N67
NETLRLFPVVSRVTR

CYP3A43

361

Q9HB55
FSAVRTVRVLRPLRA

CACNA1G

176

O43497
LATRRPTFQELQRVL

ANKZF1

326

Q9H8Y5
SRVSSISAIRFRIDP

FRMPD1

936

Q5SYB0
VGFSRTPTISDRNRL

CYP17A1

336

P05093
LAIVDQRPSSRASSR

GJA1

356

P17302
QLEILSPSRSARVQF

FASTKD1

646

Q53R41
RILNSPVSLARRNSS

HUNK

581

P57058
PVSLARRNSSERTLS

HUNK

586

P57058
QPRRVAAISLATRVS

DHX33

126

Q9H6R0
TALRSAATARLFRPL

CERS1

71

P27544
FTDAVIQERRRTLPS

CYP4F2

266

P78329
TALSPRRFVVLLIFS

FLVCR1

101

Q9Y5Y0
TNEPSTRVRFINLAR

MARCHF7

661

Q9H992
SFLARSRSAVTLPRN

MAP7D1

306

Q3KQU3
RQRDPSSFLREIRTI

ITGA10

311

O75578
VTASSFCRRRLPTVL

IMP3

101

Q9NV31
QLRTLPAAAFRNLSR

GP5

301

P40197
RALPRALFRNLSSLE

GP5

376

P40197
SISPFSIESTRRQRR

KLF12

291

Q9Y4X4
PLSRAASFASRVRRL

CUL9

1411

Q8IWT3
VPARRQTLLFSATLT

DDX49

176

Q9Y6V7
FTDAVIQERRRTLPS

CYP4F3

266

Q08477
RTAFSPSQLLRLERA

EMX1

196

Q04741
RLSRLEDRFNSTLGP

EMILIN1

406

Q9Y6C2
SPISLEFRLLQTANR

CELSR3

2461

Q9NYQ7
DSFRSRLNPLVQRSS

FAM83H

666

Q6ZRV2
SRCFRLLFPSNRETL

HELZ2

1751

Q9BYK8
GRLSRFPRFVNVTVT

AZU1

161

P20160
RSPLSRAFQLVEEIR

SCAP

116

Q12770
RESPLLARARRTESF

KCTD3

651

Q9Y597
ILRTSSNDRRPFIAL

DPY19L2P2

126

Q6ZN68
AAQSRRSVPLLRAIS

TBRG4

266

Q969Z0
SPSLIFTNRHEVRRI

LRP8

421

Q14114
RRTLFSRNLSEPRAI

LRP8

531

Q14114
AALSVRPFALRRLSA

PKD1

3881

P98161
PRNLDSRTFITIGDR

MAP2K3

41

P46734
VNATFERVLLRLSTP

GUCY1A2

371

P33402
EAPRRSIATFQSRLA

ALOX15B

631

O15296
IVRLSTNHFRLTSRP

PIWIL1

111

Q96J94
FTSRRPALEARLQLI

FAN1

876

Q9Y2M0
FQVARPRFSATRTGL

SYNPO2L

951

Q9H987
RSLLQSSQRRIPEFS

DARS2

31

Q6PI48
SRRESRLPFLFTLVA

SORL1

6

Q92673
RLTIVNSSVLDRPRA

SORL1

866

Q92673
FVSPTLFRVIRLARI

SCN4A

1441

P35499
LSQIFRQARASTPAI

SPATA5L1

546

Q9BVQ7
STRPQRSFLSRVVRA

SYNE2

6821

Q8WXH0
RSFLSRVVRAALPLQ

SYNE2

6826

Q8WXH0
TLSILFQQRVRPTSD

NCKAP5

251

O14513
QTRRPKRRTQLSSSF

TAF1C

746

Q15572
FLTFSIIAILSQRPR

MEP1A

731

Q16819
RAFLPLRHRSSSEIT

SIPA1L3

161

O60292
LPVRNSLRRENELFS

MYCBP2

1671

O75592
RARISPFASDIRTIS

RD3

156

Q7Z3Z2
LRVSFSPARSRALRL

ITGAL

781

P20701
SPARSRALRLTAFAS

ITGAL

786

P20701
AARFSRPTAARRLLE

NOTCH4

1641

Q99466
RDLSSLRRLAQSFRP

SREBF1

1016

P36956
ENSRLTSVPTLRRFA

BCO1

346

Q9HAY6
SRPVSRRLVSLIFNS

NCAPG2

511

Q86XI2
QRFLSREVDVFSPLR

CNNM3

501

Q8NE01
TRSPVTFLSDLRSNL

CNOT1

2186

A5YKK6
SRALTELQRQRLEPF

RNF31

606

Q96EP0
SRILASEIRSNFPKR

THEMIS

316

Q8N1K5
DSSSGPQRLVSFRLI

TMEM199

46

Q8N511
FSLFSDPRSTRLTRI

ZER1

71

Q7Z7L7
RVAFISLSPVRRREA

UBN2

6

Q6ZU65
LTRNSFALVPSLQRL

TLR3

471

O15455
DLRRSQPRGTFTLST

TTBK1

116

Q5TCY1
LSRESLFRSGVQTLP

TMTC1

466

Q8IUR5
RFRQSLPLSRSASQT

SRCIN1

161

Q9C0H9
DRTSSFRQILPRFRS

SYNGAP1

151

Q96PV0
SRRITPAEISSLFER

SHANK3

746

Q9BYB0
FQLDRRILSSIFPER

SPATC1

451

Q76KD6
RDFTIFRSLGQRPSL

SEMA3B

196

Q13214
AHLRPTSLVQRRFSE

TNKS1BP1

416

Q9C0C2
SRTSTIFLNGNRERP

TNXB

4041

P22105
RNRNSFKLSRVPLST

NISCH

936

Q9Y2I1
APQTSILDLRFNRIR

PXDN

61

Q92626
SSRIFPSLRRSVKRN

SCN8A

626

Q9UQD0
FALTPRQVELIRNSR

PIAS4

166

Q8N2W9
DLFRLATRFIQRSPV

TNPO3

751

Q9Y5L0
ATRFIQRSPVTLLRS

TNPO3

756

Q9Y5L0
SIARRAVRVLLPFAT

ZBED5

626

Q49AG3
VQENIPALRRSSSFL

SRY

21

Q05066
QEAATLAPTRRSRLA

PIEZO1

171

Q92508
RRVPLFSLRFRPASS

nan

11

Q8N1Y9
RSTVARIQFRLPDGS

UBXN4

316

Q92575
SSLRKRPSRISRTFF

ZNF169

151

Q14929
FLFVLSDAPRREQIR

USP54

1661

Q70EL1
FSRLNFLQRVRTSPE

VPS13D

2731

Q5THJ4
SFVNPLSGRRSFNRT

MYOZ2

221

Q9NPC6
SESRPIRRAAQLTAF

NCBP2AS2

21

Q69YL0
FSSLIQREPSSRLRS

NEDD4L

326

Q96PU5