Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	growth factor binding	IGFBP1 IGFBP2 WFIKKN1 WFIKKN2 LRP2 LTBP3	5.39e-06	156	57	6	GO:0019838
GeneOntologyMolecularFunction	insulin-like growth factor I binding	IGFBP1 IGFBP2 LRP2	6.18e-06	13	57	3	GO:0031994
GeneOntologyMolecularFunction	glutamine N-acyltransferase activity	GLYATL1 GLYATL1B	8.01e-06	2	57	2	GO:0047946
GeneOntologyMolecularFunction	insulin-like growth factor binding	IGFBP1 IGFBP2 LRP2	2.07e-05	19	57	3	GO:0005520
GeneOntologyMolecularFunction	transforming growth factor beta binding	WFIKKN1 WFIKKN2 LTBP3	5.47e-05	26	57	3	GO:0050431
GeneOntologyMolecularFunction	glycine N-acyltransferase activity	GLYATL1 GLYATL1B	7.96e-05	5	57	2	GO:0047961
GeneOntologyMolecularFunction	polysaccharide binding	CLEC18A CLEC18B CLEC18C	9.37e-05	31	57	3	GO:0030247
GeneOntologyMolecularFunction	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	FUT5 FUT6	1.19e-04	6	57	2	GO:0017083
GeneOntologyMolecularFunction	insulin-like growth factor II binding	IGFBP1 IGFBP2	2.22e-04	8	57	2	GO:0031995
GeneOntologyMolecularFunction	alpha-(1->3)-fucosyltransferase activity	FUT5 FUT6	2.22e-04	8	57	2	GO:0046920
GeneOntologyMolecularFunction	phosphotyrosine residue binding	PTPN5 SYK CBLB	4.17e-04	51	57	3	GO:0001784
GeneOntologyMolecularFunction	fucosyltransferase activity	FUT5 FUT6	7.13e-04	14	57	2	GO:0008417
GeneOntologyMolecularFunction	metalloendopeptidase inhibitor activity	WFIKKN1 WFIKKN2	9.36e-04	16	57	2	GO:0008191
GeneOntologyMolecularFunction	protein phosphorylated amino acid binding	PTPN5 SYK CBLB	1.01e-03	69	57	3	GO:0045309
GeneOntologyMolecularFunction	N-acyltransferase activity	GLYATL1 GLYATL1B GTF3C4	3.10e-03	102	57	3	GO:0016410
GeneOntologyMolecularFunction	protein domain specific binding	SYK LRP2 TACC2 KEAP1 MBD2 CBLB FZD2 AXIN1	3.24e-03	875	57	8	GO:0019904
Domain	EGF-like_dom	CLEC18A FBN2 CLEC18B LRP2 CLEC18C ADAM33 LAMC3 LTBP3 OTOG	5.05e-08	249	56	9	IPR000742
Domain	EGF_3	CLEC18A FBN2 CLEC18B LRP2 CLEC18C ADAM33 LTBP3 OTOG	4.71e-07	235	56	8	PS50026
Domain	EGF	CLEC18A FBN2 CLEC18B LRP2 CLEC18C ADAM33 LAMC3 LTBP3	4.71e-07	235	56	8	SM00181
Domain	EGF_1	CLEC18A FBN2 CLEC18B LRP2 CLEC18C ADAM33 LAMC3 LTBP3	8.73e-07	255	56	8	PS00022
Domain	EGF-like_CS	CLEC18A FBN2 CLEC18B LRP2 CLEC18C ADAM33 LAMC3 LTBP3	1.04e-06	261	56	8	IPR013032
Domain	EGF_2	CLEC18A FBN2 CLEC18B LRP2 CLEC18C ADAM33 LAMC3 LTBP3	1.16e-06	265	56	8	PS01186
Domain	Growth_fac_rcpt_	FBN2 IGFBP1 IGFBP2 LRP2 LAMC3 LTBP3	7.09e-06	156	56	6	IPR009030
Domain	TIL_dom	LRP2 KCP OTOG	9.08e-06	14	56	3	IPR002919
Domain	-	CLEC18A CLEC18B CLEC18C	1.13e-05	15	56	3	3.40.33.10
Domain	CAP	CLEC18A CLEC18B CLEC18C	1.13e-05	15	56	3	PF00188
Domain	CAP_domain	CLEC18A CLEC18B CLEC18C	1.13e-05	15	56	3	IPR014044
Domain	SCP	CLEC18A CLEC18B CLEC18C	1.13e-05	15	56	3	SM00198
Domain	Allrgn_V5/Tpx1	CLEC18A CLEC18B CLEC18C	1.13e-05	15	56	3	IPR001283
Domain	cEGF	FBN2 LRP2 LTBP3	6.32e-05	26	56	3	IPR026823
Domain	cEGF	FBN2 LRP2 LTBP3	6.32e-05	26	56	3	PF12662
Domain	IGFBP1-6	IGFBP1 IGFBP2	1.31e-04	6	56	2	IPR009168
Domain	IGFBP_1-6_chordata	IGFBP1 IGFBP2	1.31e-04	6	56	2	IPR022321
Domain	TB	FBN2 LTBP3	1.84e-04	7	56	2	PF00683
Domain	Glyco_transf_10	FUT5 FUT6	2.44e-04	8	56	2	PF00852
Domain	Glyco_tran_10_N	FUT5 FUT6	2.44e-04	8	56	2	PF17039
Domain	Glyco_trans_10	FUT5 FUT6	2.44e-04	8	56	2	IPR001503
Domain	Glyco_tran_10_N	FUT5 FUT6	2.44e-04	8	56	2	IPR031481
Domain	-	FBN2 LTBP3	2.44e-04	8	56	2	3.90.290.10
Domain	C-type_lectin_CS	CLEC18A CLEC18B CLEC18C	2.89e-04	43	56	3	IPR018378
Domain	CTDL_fold	CLEC18A CLEC18B SUMF1 CLEC18C	2.97e-04	107	56	4	IPR016187
Domain	TB	FBN2 LTBP3	3.14e-04	9	56	2	PS51364
Domain	TB_dom	FBN2 LTBP3	3.14e-04	9	56	2	IPR017878
Domain	Insulin_GF-bd_Cys-rich_CS	IGFBP1 IGFBP2	4.77e-04	11	56	2	IPR017891
Domain	IGFBP_N_1	IGFBP1 IGFBP2	5.72e-04	12	56	2	PS00222
Domain	Unchr_dom_Cys-rich	KCP OTOG	6.74e-04	13	56	2	IPR014853
Domain	C8	KCP OTOG	6.74e-04	13	56	2	SM00832
Domain	VWD	KCP OTOG	1.03e-03	16	56	2	SM00216
Domain	WAP	WFIKKN1 WFIKKN2	1.03e-03	16	56	2	SM00217
Domain	VWF_type-D	KCP OTOG	1.03e-03	16	56	2	IPR001846
Domain	VWFD	KCP OTOG	1.03e-03	16	56	2	PS51233
Domain	WAP	WFIKKN1 WFIKKN2	1.03e-03	16	56	2	PF00095
Domain	VWD	KCP OTOG	1.03e-03	16	56	2	PF00094
Domain	TY	IGFBP1 IGFBP2	1.17e-03	17	56	2	SM00211
Domain	-	IGFBP1 IGFBP2	1.17e-03	17	56	2	4.10.800.10
Domain	WAP	WFIKKN1 WFIKKN2	1.17e-03	17	56	2	PS51390
Domain	THYROGLOBULIN_1_2	IGFBP1 IGFBP2	1.17e-03	17	56	2	PS51162
Domain	Thyroglobulin_1	IGFBP1 IGFBP2	1.17e-03	17	56	2	IPR000716
Domain	Thyroglobulin_1	IGFBP1 IGFBP2	1.17e-03	17	56	2	PF00086
Domain	THYROGLOBULIN_1_1	IGFBP1 IGFBP2	1.17e-03	17	56	2	PS00484
Domain	-	WFIKKN1 WFIKKN2	1.17e-03	17	56	2	4.10.75.10
Domain	-	WFIKKN1 WFIKKN2	1.31e-03	18	56	2	4.10.410.10
Domain	Prtase_inh_Kunz-CS	WFIKKN1 WFIKKN2	1.31e-03	18	56	2	IPR020901
Domain	KAZAL_1	WFIKKN1 WFIKKN2	1.31e-03	18	56	2	PS00282
Domain	IB	IGFBP1 IGFBP2	1.31e-03	18	56	2	SM00121
Domain	KU	WFIKKN1 WFIKKN2	1.31e-03	18	56	2	SM00131
Domain	VWC_out	KCP OTOG	1.46e-03	19	56	2	SM00215
Domain	NTR	WFIKKN1 WFIKKN2	1.46e-03	19	56	2	PF01759
Domain	BPTI_KUNITZ_2	WFIKKN1 WFIKKN2	1.46e-03	19	56	2	PS50279
Domain	Kunitz_BPTI	WFIKKN1 WFIKKN2	1.46e-03	19	56	2	PF00014
Domain	Netrin_module_non-TIMP	WFIKKN1 WFIKKN2	1.46e-03	19	56	2	IPR018933
Domain	BPTI_KUNITZ_1	WFIKKN1 WFIKKN2	1.46e-03	19	56	2	PS00280
Domain	IGFBP-like	IGFBP1 IGFBP2	1.62e-03	20	56	2	IPR000867
Domain	IGFBP	IGFBP1 IGFBP2	1.62e-03	20	56	2	PF00219
Domain	IGFBP_N_2	IGFBP1 IGFBP2	1.62e-03	20	56	2	PS51323
Domain	C_TYPE_LECTIN_1	CLEC18A CLEC18B CLEC18C	1.78e-03	80	56	3	PS00615
Domain	WAP_dom	WFIKKN1 WFIKKN2	1.96e-03	22	56	2	IPR008197
Domain	Lectin_C	CLEC18A CLEC18B CLEC18C	2.05e-03	84	56	3	PF00059
Domain	CLECT	CLEC18A CLEC18B CLEC18C	2.05e-03	84	56	3	SM00034
Domain	C_TYPE_LECTIN_2	CLEC18A CLEC18B CLEC18C	2.12e-03	85	56	3	PS50041
Domain	NTR	WFIKKN1 WFIKKN2	2.15e-03	23	56	2	PS50189
Domain	Netrin_domain	WFIKKN1 WFIKKN2	2.15e-03	23	56	2	IPR001134
Domain	Kunitz_BPTI	WFIKKN1 WFIKKN2	2.15e-03	23	56	2	IPR002223
Domain	C-type_lectin-like	CLEC18A CLEC18B CLEC18C	2.19e-03	86	56	3	IPR001304
Domain	EGF_CA	FBN2 LRP2 LTBP3	2.19e-03	86	56	3	PF07645
Domain	NUDIX	NUDT5 MUTYH	2.34e-03	24	56	2	PF00293
Domain	NUDIX	NUDT5 MUTYH	2.74e-03	26	56	2	PS51462
Domain	TIMP-like_OB-fold	WFIKKN1 WFIKKN2	2.74e-03	26	56	2	IPR008993
Domain	EGF_Ca-bd_CS	FBN2 LRP2 LTBP3	3.08e-03	97	56	3	IPR018097
Pathway	KEGG_MEDICUS_REFERENCE_LEWIS_X_ANTIGEN_BIOSYNTHESIS	FUT5 FUT6	8.21e-05	5	41	2	M47966
Pathway	KEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS	FUT5 FUT6	1.23e-04	6	41	2	M47967
Pathway	WP_PHOTODYNAMIC_THERAPYINDUCED_HIF1_SURVIVAL_SIGNALING	IGFBP1 IGFBP2 SLC16A1	1.79e-04	38	41	3	M39707
Pubmed	Human CLEC18 Gene Cluster Contains C-type Lectins with Differential Glycan-binding Specificity.	CLEC18A CLEC18B CLEC18C	4.88e-09	3	60	3	26170455
Pubmed	The C-type lectin-like domain superfamily.	CLEC18A CLEC18B CLEC18C	4.88e-09	3	60	3	16336259
Pubmed	Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.	CLEC18A CLEC18B CLEC18C	4.88e-09	3	60	3	33603190
Pubmed	The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation.	CLEC18A CLEC18B CLEC18C	1.95e-08	4	60	3	16709836
Pubmed	Complexes between insulin-like growth factor binding proteins and alpha-2-macroglobulin in patients with tumor.	IGFBP1 IGFBP2	2.93e-06	2	60	2	25746666
Pubmed	Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules.	WFIKKN1 WFIKKN2	2.93e-06	2	60	2	11928817
Pubmed	Expression, purification and characterization of the second Kunitz-type protease inhibitor domain of the human WFIKKN protein.	WFIKKN1 WFIKKN2	2.93e-06	2	60	2	12709070
Pubmed	TRIM46 upregulates Wnt/β-catenin signaling by inhibiting Axin1 to mediate hypoxia-induced epithelial-mesenchymal transition in HK2 cells.	TRIM46 AXIN1	2.93e-06	2	60	2	35670901
Pubmed	Inhibition of CBLB protects from lethal Candida albicans sepsis.	SYK CBLB	2.93e-06	2	60	2	27428901
Pubmed	The γ-Protocadherin-C3 isoform inhibits canonical Wnt signalling by binding to and stabilizing Axin1 at the membrane.	EMX1 AXIN1	2.93e-06	2	60	2	27530555
Pubmed	Molecular cloning of the human homolog of a striatum-enriched phosphatase (STEP) gene and chromosomal mapping of the human and murine loci.	PTPN5 OTOG	2.93e-06	2	60	2	7490079
Pubmed	Site-specific fucosylation of sialylated polylactosamines by alpha1,3/4-fucosyltransferases-V and -VI Is defined by amino acids near the N terminus of the catalytic domain.	FUT5 FUT6	2.93e-06	2	60	2	17604274
Pubmed	IGFBP-1 and IGFBP-2 are associated with a decreased pulse-wave velocity in young, healthy adults.	IGFBP1 IGFBP2	2.93e-06	2	60	2	33706704
Pubmed	Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes.	FUT5 FUT6	2.93e-06	2	60	2	1339443
Pubmed	Cubilin-, megalin-, and Dab2-dependent transcription revealed by CRISPR/Cas9 knockout in kidney proximal tubule cells.	LRP2 EMX1	2.93e-06	2	60	2	34747197
Pubmed	Raised serum levels of IGFBP-1 and IGFBP-2 in idiopathic pulmonary fibrosis.	IGFBP1 IGFBP2	2.93e-06	2	60	2	27215343
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	FBN2 RSF1 LRP2 LTBP3	7.13e-06	71	60	4	33541421
Pubmed	Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms.	FUT5 FUT6	8.77e-06	3	60	2	7650030
Pubmed	Overexpressed N-fucosylation on the cell surface driven by FUT3, 5, and 6 promotes cell motilities in metastatic pancreatic cancer cell lines.	FUT5 FUT6	8.77e-06	3	60	2	30808544
Pubmed	Physical maps of human alpha (1,3)fucosyltransferase genes FUT3-FUT6 on chromosomes 19p13.3 and 11q21.	FUT5 FUT6	8.77e-06	3	60	2	7782074
Pubmed	A Modular Organization of LRR Protein-Mediated Synaptic Adhesion Defines Synapse Identity.	LRRTM1 EMX1	8.77e-06	3	60	2	29983322
Pubmed	Sex-Specific Control of Muscle Mass: Elevated IGFBP Proteolysis and Reductions of IGF-1 Levels Are Associated with Substantial Loss of Carcass Weight in Male DU6PxIGFBP-2 Transgenic Mice.	IGFBP1 IGFBP2	8.77e-06	3	60	2	32993096
Pubmed	Immunohistochemical analysis of insulin-like growth factor-binding proteins -1, -2, and -3 in implantation sites of the mouse.	IGFBP1 IGFBP2	8.77e-06	3	60	2	9785199
Pubmed	WFIKKN1 and WFIKKN2: "Companion" proteins regulating TGFB activity.	WFIKKN1 WFIKKN2	8.77e-06	3	60	2	27325460
Pubmed	Cbl-b negatively regulates B cell antigen receptor signaling in mature B cells through ubiquitination of the tyrosine kinase Syk.	SYK CBLB	8.77e-06	3	60	2	12771181
Pubmed	Calpain proteolysis of insulin-like growth factor binding protein (IGFBP) -2 and -3, but not of IGFBP-1.	IGFBP1 IGFBP2	8.77e-06	3	60	2	17655506
Pubmed	A mouse knockout library for secreted and transmembrane proteins.	CLEC18A CLEC18B SUMF1 CLEC18C ADAM33 LRRTM1 SEZ6L2	1.43e-05	460	60	7	20562862
Pubmed	miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway.	FUT5 FUT6	1.75e-05	4	60	2	28771224
Pubmed	Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11.	WFIKKN1 WFIKKN2	1.75e-05	4	60	2	18596030
Pubmed	Selective developmental regulation of gene expression for insulin-like growth factor-binding proteins in mouse spinal cord.	IGFBP1 IGFBP2	1.75e-05	4	60	2	10888943
Pubmed	A cross-sectional analysis of the associations between adult height, BMI and serum concentrations of IGF-I and IGFBP-1 -2 and -3 in the European Prospective Investigation into Cancer and Nutrition (EPIC).	IGFBP1 IGFBP2	1.75e-05	4	60	2	20731527
Pubmed	Insulin-like growth factor axis and risk of type 2 diabetes in women.	IGFBP1 IGFBP2	1.75e-05	4	60	2	22554827
Pubmed	Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells.	FUT5 FUT6	1.75e-05	4	60	2	19349624
Pubmed	Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions.	IGFBP1 IGFBP2	1.75e-05	4	60	2	9408744
Pubmed	Serum levels of insulin-like growth factors (IGFs) and their binding proteins (IGFBPs), -1, -2, -3, in oral cancer.	IGFBP1 IGFBP2	1.75e-05	4	60	2	17113753
Pubmed	Temporal changes in insulin-like growth factors I and II and in insulin-like growth factor binding proteins 1, 2, and 3 in human milk.	IGFBP1 IGFBP2	2.92e-05	5	60	2	18259111
Pubmed	Tyrosine phosphorylation and complex formation of Cbl-b upon T cell receptor stimulation.	SYK CBLB	2.92e-05	5	60	2	10022120
Pubmed	Delayed mammary gland involution in mice with mutation of the insulin-like growth factor binding protein 5 gene.	IGFBP1 IGFBP2	2.92e-05	5	60	2	17255210
Pubmed	Insulin-like growth factors and related proteins in plasma and cerebrospinal fluids of HIV-positive individuals.	IGFBP1 IGFBP2	2.92e-05	5	60	2	25890304
Pubmed	Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.	FUT5 FUT6	2.92e-05	5	60	2	29593094
Pubmed	Free and total insulin-like growth factor (IGF)-I, -II, and IGF binding protein-1, -2, and -3 serum levels in patients with active thyroid eye disease.	IGFBP1 IGFBP2	2.92e-05	5	60	2	12519841
Pubmed	Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling.	CLEC18A CLEC18B CLEC18C	3.64e-05	37	60	3	22432025
Pubmed	FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice.	FBN2 IGFBP1 IGFBP2	3.94e-05	38	60	3	26134413
Pubmed	Insulin-like growth factor binding proteins are transcribed by preimplantation mouse embryos.	IGFBP1 IGFBP2	4.37e-05	6	60	2	7511095
Pubmed	Gene expression of the six insulin-like growth factor binding proteins in the mouse conceptus during mid- and late gestation.	IGFBP1 IGFBP2	4.37e-05	6	60	2	7684980
Pubmed	Generation of antisera to mouse insulin-like growth factor binding proteins (IGFBP)-1 to -6: comparison of IGFBP protein and messenger ribonucleic acid localization in the mouse embryo.	IGFBP1 IGFBP2	4.37e-05	6	60	2	10579362
Pubmed	Insulin-like growth factor (IGF)-binding proteins in serum--do they have additional roles besides modulating the endocrine IGF actions?	IGFBP1 IGFBP2	4.37e-05	6	60	2	8923818
Pubmed	Simultaneous detection of multiple gene expression in mouse and human individual preimplantation embryos.	IGFBP1 IGFBP2	4.37e-05	6	60	2	9093203
Pubmed	Disruption of the GH Receptor Gene in Adult Mice Increases Maximal Lifespan in Females.	IGFBP1 IGFBP2	4.37e-05	6	60	2	27732088
Pubmed	Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2.	WFIKKN1 WFIKKN2	4.37e-05	6	60	2	23829672
Pubmed	Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b.	SYK CBLB	4.37e-05	6	60	2	17493844
Pubmed	Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span.	IGFBP1 IGFBP2	4.37e-05	6	60	2	12933651
Pubmed	Insulin-like growth factors and insulin-like growth factor binding proteins in adult patients with severe liver disease before and after orthotopic liver transplantation.	IGFBP1 IGFBP2	4.37e-05	6	60	2	12006706
Pubmed	Regulation of metabolic water and protein compartments by insulin-like growth factor-I and testosterone in growth hormone-deficient lit/lit mice.	IGFBP1 IGFBP2	4.37e-05	6	60	2	7510770
Pubmed	Growth hormone deficiency in 'little' mice results in aberrant body composition, reduced insulin-like growth factor-I and insulin-like growth factor-binding protein-3 (IGFBP-3), but does not affect IGFBP-2, -1 or -4.	IGFBP1 IGFBP2	4.37e-05	6	60	2	7679139
Pubmed	Transgenic mouse models for studying the functions of insulin-like growth factor-binding proteins.	IGFBP1 IGFBP2	4.37e-05	6	60	2	10744620
Pubmed	Selective alterations in organ sizes in mice with a targeted disruption of the insulin-like growth factor binding protein-2 gene.	IGFBP1 IGFBP2	4.37e-05	6	60	2	10976924
Pubmed	cDNA cloning and mRNA expression of the six mouse insulin-like growth factor binding proteins.	IGFBP1 IGFBP2	4.37e-05	6	60	2	7529732
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	ACP6 CLEC18A CLEC18B CD177 SUMF1 WFIKKN2 ADAM33 LRRTM1 SEZ6L2	4.57e-05	985	60	9	12975309
Pubmed	Transferrin is an insulin-like growth factor-binding protein-3 binding protein.	IGFBP1 IGFBP2	6.11e-05	7	60	2	11297622
Pubmed	Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers.	IGFBP1 IGFBP2	8.14e-05	8	60	2	19843326
Pubmed	Biosensor measurement of the interaction kinetics between insulin-like growth factors and their binding proteins.	IGFBP1 IGFBP2	8.14e-05	8	60	2	10407151
Pubmed	The expression of insulin-like growth factor and insulin-like growth factor binding protein mRNAs in mouse placenta.	IGFBP1 IGFBP2	8.14e-05	8	60	2	16338473
Pubmed	Gene expression of the insulin-like growth factor system during mouse kidney development.	IGFBP1 IGFBP2	1.05e-04	9	60	2	9324049
Pubmed	GASP-2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP-1 transgenics.	WFIKKN1 WFIKKN2	1.05e-04	9	60	2	31960486
Pubmed	WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity.	WFIKKN1 WFIKKN2	1.05e-04	9	60	2	21054789
Pubmed	mRNA expression patterns of the IGF system during mouse limb bud development, determined by whole mount in situ hybridization.	IGFBP1 IGFBP2	1.05e-04	9	60	2	9685224
Pubmed	Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells.	FZD2 AXIN1	1.05e-04	9	60	2	19038973
Pubmed	mRNA and protein localization of the IGF system during mouse embryonic development in areas with apoptosis.	IGFBP1 IGFBP2	1.05e-04	9	60	2	10502456
Pubmed	Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma.	IGFBP1 IGFBP2	1.31e-04	10	60	2	19124510
Pubmed	Identification of two clusters of mouse insulin-like growth factor binding protein genes on chromosomes 1 and 11.	IGFBP1 IGFBP2	1.31e-04	10	60	2	7525452
Pubmed	IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes.	IGFBP1 IGFBP2	1.59e-04	11	60	2	15721138
Pubmed	Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis.	IGFBP1 IGFBP2	1.59e-04	11	60	2	7750499
Pubmed	Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease.	IGFBP1 IGFBP2 FZD2	1.89e-04	64	60	3	24431302
Pubmed	Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex.	TRNP1 CAMKK1 EMX1	1.89e-04	64	60	3	20798045
Pubmed	Nonsyndromic Genetic Hyperinsulinism Overview	SLC16A1 PMM2	1.91e-04	12	60	2	20301549
Pubmed	Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis.	IGFBP1 IGFBP2	2.26e-04	13	60	2	35741102
Pubmed	Overexpression of thioredoxin-1 reduces oxidative stress in the placenta of transgenic mice and promotes fetal growth via glucose metabolism.	IGFBP1 IGFBP2	2.63e-04	14	60	2	18450962
Pubmed	Expression of insulin-like growth factor binding proteins during mouse cochlear development.	IGFBP1 IGFBP2	2.63e-04	14	60	2	23813480
Pubmed	Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration.	EMX1 FZD2	2.63e-04	14	60	2	35649377
Pubmed	Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.	WFIKKN1 TPSG1 AXIN1	2.90e-04	74	60	3	11157797
Pubmed	Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism.	FUT5 FUT6	3.03e-04	15	60	2	11698403
Pubmed	Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2.	WFIKKN1 WFIKKN2	3.03e-04	15	60	2	24019467
Pubmed	Genomic analysis of mouse retinal development.	TRNP1 SLC16A1 ACOT7 TACC2 RNF187 SEZ6L2 FZD2 AXIN1	3.22e-04	1006	60	8	15226823
Pubmed	Differential regulation of NF-κB-mediated proviral and antiviral host gene expression by primate lentiviral Nef and Vpu proteins.	IGFBP1 IGFBP2	3.46e-04	16	60	2	25620704
Pubmed	A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales.	FBN2 CSMD3	3.91e-04	17	60	2	22832960
Pubmed	Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice.	IGFBP1 IGFBP2	3.91e-04	17	60	2	9175833
Pubmed	Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.	KEAP1 AXIN1	3.91e-04	17	60	2	17510365
Pubmed	Eighteen insulin-like growth factor pathway genes, circulating levels of IGF-I and its binding protein, and risk of prostate and breast cancer.	IGFBP1 IGFBP2	4.40e-04	18	60	2	20810604
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF469 FBN2 IGFBP1 SLC16A1 RSF1 LRP2 KEAP1 MBD2	6.39e-04	1116	60	8	31753913
Pubmed	Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.	LAMC3 CSMD3	6.61e-04	22	60	2	35245678
Pubmed	Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior.	EMX1 FZD2	7.23e-04	23	60	2	20445055
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TXNL1 SLC16A1 LRP2 KEAP1 GTF3C4	7.77e-04	418	60	5	34709266
Pubmed	Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span.	IGFBP1 IGFBP2	8.56e-04	25	60	2	23563309
Pubmed	Role of the focal adhesion protein TRIM15 in colon cancer development.	SYK KEAP1	8.56e-04	25	60	2	25450970
Pubmed	Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation.	IGFBP1 IGFBP2	9.26e-04	26	60	2	27861515
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	TRIM46 FBN2 IGFBP2 WFIKKN1 FAAP20 TACC2 FZD2 MUTYH	1.11e-03	1215	60	8	15146197
Pubmed	Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.	ATF7 FBN2	1.15e-03	29	60	2	21998595
GeneFamily	Insulin like growth factor binding proteins	IGFBP1 IGFBP2	8.63e-05	6	44	2	1065
GeneFamily	C-type lectin domain family	CLEC18A CLEC18B CLEC18C	2.02e-04	47	44	3	494
GeneFamily	Fucosyltransferases\|Blood group antigens	FUT5 FUT6	4.44e-04	13	44	2	434
GeneFamily	WAP four-disulfide core domain containing\|Fibronectin type III domain containing	WFIKKN1 WFIKKN2	8.64e-04	18	44	2	361
Coexpression	NABA_MATRISOME	CLEC18A FBN2 IGFBP1 IGFBP2 CLEC18B WFIKKN1 WFIKKN2 KCP CLEC18C ADAM33 LAMC3 LTBP3 CPN2 OTOG	3.74e-08	1008	59	14	MM17056
Coexpression	NABA_MATRISOME	CLEC18A FBN2 IGFBP1 IGFBP2 CLEC18B WFIKKN1 WFIKKN2 KCP CLEC18C ADAM33 LAMC3 LTBP3 CPN2 OTOG	4.66e-08	1026	59	14	M5889
Coexpression	NABA_ECM_GLYCOPROTEINS	FBN2 IGFBP1 IGFBP2 KCP LAMC3 LTBP3 OTOG	2.42e-07	191	59	7	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	FBN2 IGFBP1 IGFBP2 KCP LAMC3 LTBP3 OTOG	2.88e-07	196	59	7	M3008
Coexpression	DESCARTES_FETAL_KIDNEY_METANEPHRIC_CELLS	GLYATL1 CLEC18B WFIKKN1 LRP2 CLEC18C LRRTM1	1.45e-06	157	59	6	M40223
Coexpression	NABA_CORE_MATRISOME	FBN2 IGFBP1 IGFBP2 KCP LAMC3 LTBP3 OTOG	2.46e-06	270	59	7	MM17057
Coexpression	NABA_CORE_MATRISOME	FBN2 IGFBP1 IGFBP2 KCP LAMC3 LTBP3 OTOG	2.78e-06	275	59	7	M5884
Coexpression	MARTENS_TRETINOIN_RESPONSE_UP	TRIM46 ZSCAN1 CAMKK1 ADAM33 LAMC3 TPSG1 FUT6 EMX1 KRT38 OTOG	1.91e-05	855	59	10	M2098
Coexpression	GSE30083_SP2_VS_SP4_THYMOCYTE_UP	LRP2 ACOT7 LAMC3 TACC2 CPN2	8.82e-05	200	59	5	M5034
CoexpressionAtlas	kidney	GLYATL1 CLEC18A CLEC18B LRP2 KCP CLEC18C FUT6 EMX1	2.60e-06	323	58	8	kidney
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_500	PTPN5 CLEC18A CLEC18B WFIKKN1 LRP2 CLEC18C FUT5 EMX1	5.68e-05	495	58	8	PCBC_ECTO_500
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	ZNF469 FBN2 ACOT7 ADAM33 FZD2	3.07e-06	167	60	5	9062577a4b7902c9a888d706589d1b05221c0fa8
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CLEC18A FBN2 CLEC18B WFIKKN2 CLEC18C	5.06e-06	185	60	5	8ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CLEC18A FBN2 CLEC18B WFIKKN2 CLEC18C	5.06e-06	185	60	5	b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Breast_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	CLEC18A FBN2 CLEC18B OTOG	1.10e-05	102	60	4	010b446526c0fdfde45cdc04dc2395cbbe60e820
ToppCell	Thalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--\|Thalamus / BrainAtlas - Mouse McCarroll V32	SYK ADAM33 TPSG1 WDFY4	1.54e-05	111	60	4	a1b7940c6fa0e5a58aa4798b604469d79f33fa44
ToppCell	Thalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	SYK ADAM33 TPSG1 WDFY4	1.54e-05	111	60	4	d1ec8e8e9adb11511b4ef363cc6f99286e2cc842
ToppCell	Thalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)\|Thalamus / BrainAtlas - Mouse McCarroll V32	SYK ADAM33 TPSG1 WDFY4	1.54e-05	111	60	4	567e5ac2c78d45db207067f0f152bb24ed048c50
ToppCell	Thalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)\|Thalamus / BrainAtlas - Mouse McCarroll V32	SYK ADAM33 TPSG1 WDFY4	1.54e-05	111	60	4	fd7aa25e83a0d762969e3966a658652da40c490e
ToppCell	Thalamus-Hematopoietic-MACROPHAGE\|Thalamus / BrainAtlas - Mouse McCarroll V32	SYK ADAM33 TPSG1 WDFY4	1.54e-05	111	60	4	d48561078c387ac856c1c30e3d7a3e75ebde942e
ToppCell	TCGA-Kidney\|World / Sample_Type by Project: Shred V9	CLEC18A CLEC18B LRP2 EMX1	5.14e-05	151	60	4	e31974c0d0a0c644205a0ee6013ab74a09d8a306
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN2 IGFBP2 SYK LAMC3	5.98e-05	157	60	4	beab0ac47202266b04543c02cfcdda012375e879
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	ZNF469 FBN2 ZSCAN1 SEZ6L2	7.08e-05	164	60	4	9b4a6007abae992db871d9f6f731d5af724de30d
ToppCell	Control-B_cells-Activated_B_cells\|Control / group, cell type (main and fine annotations)	GLYATL1 SYK GLYATL1B WDFY4	7.77e-05	168	60	4	a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GLYATL1 SLC16A1 LRP2 FUT6	7.77e-05	168	60	4	fa0d251693935116adf633d02b7ec4a295100865
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-Th17\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRIM46 ZNF469 KCP ANO8	7.77e-05	168	60	4	97bf074b91c9ae0064edc31fa4a2658ffdcfefa3
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 IGFBP1 LRP2 ACOT7	8.32e-05	171	60	4	8e7223ba447947cdf4e1c82a52fd90439cf3d8f6
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACP6 FAAP20 KCP FZD2	8.90e-05	174	60	4	d77fa525d5c87c190b4a10787b270eabd16c610f
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGFBP2 SLC16A1 LRP2 ADAM33	9.30e-05	176	60	4	8e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGFBP2 SLC16A1 LRP2 ADAM33	9.30e-05	176	60	4	ed575330a08a6748ea4b28433292c8cfd157d444
ToppCell	facs-Pancreas-Exocrine-24m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGFBP2 CD177 LRP2 CSMD3	1.01e-04	180	60	4	72310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBN2 ADAM33 LAMC3 SEZ6L2	1.04e-04	181	60	4	35bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLYATL1 FBN2 ADAM33 LAMC3	1.06e-04	182	60	4	3d7a8d2ee2137b098248597058974ef5ae09c19e
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIM46 TRNP1 FUT6 PMM2	1.06e-04	182	60	4	818b5155ec81f0059048d6070a108116ecd72e3c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GLYATL1 CLEC18A LRP2 FUT6	1.08e-04	183	60	4	85446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRNP1 IGFBP2 LRP2 EMX1	1.08e-04	183	60	4	03649492c37f9b274a1caf3e2132ce2915cf1df5
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 LRP2 CSMD3 OTOG	1.10e-04	184	60	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 LRP2 CSMD3 OTOG	1.10e-04	184	60	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 LRP2 CSMD3 OTOG	1.10e-04	184	60	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC18A IGFBP2 LTBP3 LRRTM1	1.13e-04	185	60	4	872720275789d249c9859de825a923803d458875
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC18A IGFBP2 LTBP3 LRRTM1	1.17e-04	187	60	4	806075c2531a7f5c1da38b85ea494a3b4b5e92ec
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	FBN2 SLC16A1 WFIKKN1 LRP2	1.38e-04	195	60	4	2fa0216ba493d9722324c0a9a0c59c40e72b3c4e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells-retina_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	FBN2 SLC16A1 WFIKKN1 LRP2	1.38e-04	195	60	4	06a437459717dc3c41ec343b1ec57cf910ecbdd8
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CLEC18A TPSG1 EMX1	1.42e-04	75	60	3	3bc5df14f21c1c93c2a0fd5fc47bc5d146ba87a2
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PTPN5 FBN2 CSMD3 FZD2	1.44e-04	197	60	4	2cb1f557ce1400398975de94638126b4522567f3
ToppCell	18-Airway\|18 / Age, Tissue, Lineage and Cell class	FBN2 IGFBP2 ADAM33 CCDC17	1.46e-04	198	60	4	3cdfcc6445858c3c54058bbd90b20b88b1771cca
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TRNP1 CD177 ADAM33 FZD2	1.52e-04	200	60	4	24e13b6d9d2d8b29df1f02544ea9c50084d9e75c
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GLYATL1 FUT6 DOP1B PMM2	1.52e-04	200	60	4	ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TRNP1 CD177 ADAM33 FZD2	1.52e-04	200	60	4	f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	ZNF469 CLEC18B WFIKKN2 CSMD3	1.52e-04	200	60	4	fe772d98c461c973dfc082e1fc50117c27ced804
Disease	alpha-(1;3)-fucosyltransferase 5 measurement	FUT5 FUT6	2.35e-05	4	59	2	EFO_0021979
Disease	galactoside 3(4)-L-fucosyltransferase measurement	FUT5 FUT6	8.20e-05	7	59	2	EFO_0021853
Disease	alpha-(1,3)-fucosyltransferase 5 measurement	FUT5 FUT6	8.20e-05	7	59	2	EFO_0020136
Disease	Colonic Neoplasms	IGFBP1 SLC16A1 FZD2 MUTYH	2.47e-04	152	59	4	C0009375
Disease	stomach carcinoma (is_implicated_in)	CBLB MUTYH	2.56e-04	12	59	2	DOID:5517 (is_implicated_in)
Disease	Malignant tumor of colon	IGFBP1 SLC16A1 FZD2 MUTYH	2.93e-04	159	59	4	C0007102
Disease	COVID-19, mortality	SUMF1 LRP2 ADAM33 LTBP3	3.78e-04	170	59	4	EFO_0004352, MONDO_0100096
Disease	serum carcinoembryonic antigen measurement	FUT5 FUT6	7.30e-04	20	59	2	EFO_0005760
Disease	Child Development Disorders, Specific	LRP2 WDFY4	1.54e-03	29	59	2	C0085997
Disease	Child Development Deviations	LRP2 WDFY4	1.54e-03	29	59	2	C0085996
Disease	Developmental Disabilities	LRP2 WDFY4	1.65e-03	30	59	2	C0008073
Disease	type 1 diabetes mellitus (implicated_via_orthology)	MBD2 CBLB	2.78e-03	39	59	2	DOID:9744 (implicated_via_orthology)
Disease	Secondary Biliary Cholangitis	IGFBP1 KEAP1	3.21e-03	42	59	2	C0238065
Disease	Biliary cirrhosis	IGFBP1 KEAP1	3.21e-03	42	59	2	C0023892
Disease	Biliary Cirrhosis, Primary, 1	IGFBP1 KEAP1	3.21e-03	42	59	2	C4551595
Disease	candidiasis (implicated_via_orthology)	FUT5 FUT6	3.52e-03	44	59	2	DOID:1508 (implicated_via_orthology)
Disease	osteoarthritis, knee	CLEC18A SLC16A1 SUMF1	3.93e-03	158	59	3	EFO_0004616

Protein segments in the cluster

Peptide	Gene	Start	Entry
ADLPPCGACITGRIM	ACOT7	46	O00154
GEPALLPCGTCDMVF	CCDC17	6	Q96LX7
ARPAQPCPMGCDCFV	CPN2	16	P22792
PVPICRAEDACGGTM	CSMD3	231	Q7Z407
AGALCRQAMGDCDLP	ADAM33	471	Q9BZ11
MGDDRPFVCNAPGCG	ATF7	1	P17544
ADPGSLRCPVCLSME	CD177	126	Q8N6Q3
QALAAAECPPCAMAG	ANO8	1166	Q9HCE9
LRCSAMPTEGECAPG	PCDHA9	721	Q9Y5H5
GALDMCCSERLPGLP	PTPN5	21	P54829
LNCCVAGALMRPIGP	SLC16A1	186	P53985
PSVEGAAALRSCPMC	FAAP20	136	Q6NZ36
GACFQMLPAAPSGCP	LRRTM1	26	Q86UE6
EKGERMGCPAGCPRE	SYK	586	P43405
MEGGPAVCCQDPRAE	CAMKK1	1	Q8N5S9
EENCCAPIPMGGRAY	DOP1B	1141	Q9Y3R5
GCQPGAEANIAPMCL	KRT38	31	O76015
EGSRCCSIIDPFGMP	CBLB	431	Q13191
PMCALPLGAACGVAT	IGFBP1	61	P08833
PAAVAAVAGGARMPC	IGFBP2	61	P18065
ARMPCAELVREPGCG	IGFBP2	71	P18065
GDIAECSPAVCMDPG	NUDT5	121	Q9UKK9
CAAPCEPARPDGSMF	FZD2	221	Q14332
CIEDLPAACMLGPEG	GLYATL1	201	Q969I3
CALMAPCGPAAGPAA	MIR1-1HG	6	Q9H1L0
NSDEAGCPTRPPGMC	LRP2	1216	P98164
MRAHPGGGRCCPEQE	MBD2	1	Q9UBB5
HFPPRCVDMGCAGLR	AXIN1	446	O15169
CLGALPAACMLGPEG	GLYATL1B	201	A0A0U1RQE8
ALPRCSEMVPGTADC	FUT6	76	P51993
EAEPCGPGRGICMNT	LTBP3	621	Q9NS15
MQPDPRPSGAGACCR	KEAP1	1	Q14145
MCLAGCTPRKAAAPG	EMX1	1	Q04741
RCDCPPGLAVGMDGR	FBN2	681	P35556
AAAAVMAPPGCPGSC	RSF1	6	Q96T23
GEPMRPLAEECCQLG	IPO4	556	Q8TEX9
GVMSCDSRAPAAACP	OTOG	871	Q6ZRI0
MAAPGPALCLFDVDG	PMM2	1	O15305
LPRCSEMVPGAADCN	FUT5	91	Q11128
IMFPCPACQGDVELG	TRIM46	126	Q7Z4K8
PDMLCARGPGDACQD	TPSG1	206	Q9NRR2
MALPAGPAEAACALC	RNF187	1	Q5TA31
AGPLCAACRMAAGPE	RNF187	101	Q5TA31
PRCLPRPASCMAFGD	KCP	1206	Q6ZWJ8
AKPSACDGMIAECPG	MUTYH	46	Q9UIF7
CDGMIAECPGAPAGL	MUTYH	51	Q9UIF7
PACKAMCGGELSEPA	SEZ6L2	521	Q6UXD5
MAAPALGLVCGRCPE	SUMF1	1	Q8NBK3
AGGLCEVPRNPCRMS	CLEC18A	221	A5D8T8
AGGLCEVPRNPCRMS	CLEC18B	221	Q6UXF7
AGGLCEVPRNPCRMS	CLEC18C	221	Q8NCF0
PRGGRPFQCADCGMV	ZSCAN1	286	Q8NBB4
PEGAITCCCLMEGPA	WDFY4	3066	Q6ZS81
RGCPDGLCPLDMFLN	ACP6	386	Q9NPH0
CQDPACSDKAPGMEG	TACC2	1746	O95359
PMGCDANGRCLLAAL	GTF3C4	171	Q9UKN8
LSMPADPCEGGARSC	ZNF839	256	A8K0R7
ALRSPPAACAGEMGA	ZNF469	1216	Q96JG9
PAACAGEMGASPGLL	ZNF469	1221	Q96JG9
PQRGGCMTFPARGCD	WFIKKN1	321	Q96NZ8
MPGCRISACGPGAQE	TRNP1	1	Q6NT89
MRGCGPCLRIAPAFS	TXNL1	31	O43396
LACMSGPLAACSLPA	WFIKKN2	376	Q8TEU8
ALLAPRAAGAGMGAC	LAMC3	11	Q9Y6N6