Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24

1.77e-11371078GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24

2.23e-11381078GO:0070001
GeneOntologyMolecularFunctiontranscription coactivator activity

NCOA3 MAK KAT6A ARID1A ZFPM2 TSC22D1 KMT2D MED12L SMARCA2 CCAR1 MED12 EP300 NOTCH1

8.85e-0930310713GO:0003713
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 CPEB3 ERVK-7 ERVK-10 ERVK-8

7.64e-08211075GO:0035613
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

2.50e-07111074GO:0004523
GeneOntologyMolecularFunctiontranscription coregulator activity

NCOA3 MAK KAT6A ARID1A ZFPM2 HNRNPU TSC22D1 KMT2D TOB1 MED12L SMARCA2 CCAR1 MED12 EP300 NOTCH1

3.17e-0756210715GO:0003712
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

7.48e-07141074GO:0003964
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 EP400 POLG CHD9 ERVK-7 ERVK-10 ARID1A BPTF ERVK-8 SMARCA2

1.47e-0626210710GO:0140097
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 POLG ERVK-7 ERVK-10 ERVK-8

1.75e-06381075GO:0034061
GeneOntologyMolecularFunctionchromatin binding

NCOA3 EP400 YBX1 POLG KAT6A RELA ARID1A HNRNPU CRX PHC3 ASCL1 SMARCA2 PRDM15 MED12 EP300 NOTCH1

1.98e-0673910716GO:0003682
GeneOntologyMolecularFunctiontranscription factor binding

NCOA3 KAT6A RELA ARID1A TFDP2 ZFPM2 HNRNPU CRX BPTF GTF2A1 ASCL1 MED12L BSN MED12 EP300

1.16e-0575310715GO:0008134
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

NCOA3 MAK COL11A2 YBX1 KAT6A ARID1A WNK1 ZFPM2 HNRNPU TSC22D1 KMT2D TOB1 TNRC6A MED12L SMARCA2 CCAR1 MED12 EP300 NOTCH1

1.17e-05116010719GO:0030674
GeneOntologyMolecularFunctionzinc ion binding

TET2 ERVK-6 ZSWIM3 KAT6A ERVK-7 ERVK-21 ERVK-9 ERVK-10 ZFPM2 PHC3 SEC24B ERVK-8 CIZ1 ERVK-19 ERVK-24 EP300

2.08e-0589110716GO:0008270
GeneOntologyMolecularFunctionmolecular adaptor activity

NCOA3 MAK COL11A2 YBX1 KAT6A ARID1A WNK1 DCTN1 ZFPM2 HNRNPU TSC22D1 KMT2D TOB1 TNRC6A MED12L SMARCA2 CCAR1 MED12 EP300 NOTCH1

3.06e-05135610720GO:0060090
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8

4.49e-05371074GO:0016891
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

EP400 CHD9 ARID1A SMARCA2

4.49e-05371074GO:0140658
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 SMG6

6.61e-05791075GO:0004521
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8

1.07e-04461074GO:0016893
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-6 EP400 POLG CHD9 ERVK-7 ERVK-10 ARID1A GGT5 BPTF ERVK-8 SMARCA2 SMG6

1.76e-0464510712GO:0140640
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

NCOA3 HNRNPU SCAF4 GTF2A1

4.35e-04661074GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

NCOA3 HNRNPU SCAF4 GTF2A1

4.35e-04661074GO:0001098
GeneOntologyMolecularFunctiontransition metal ion binding

TET2 ERVK-6 ZSWIM3 KAT6A ERVK-7 ERVK-21 ERVK-9 ERVK-10 ZFPM2 PHC3 SEC24B ERVK-8 CIZ1 ERVK-19 ERVK-24 EP300

5.81e-04118910716GO:0046914
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

EP400 CHD9 ARID1A BPTF SMARCA2

6.09e-041271075GO:0008094
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

TFEB NCOA3 SP4 RELA RFXAP TFDP2 HNRNPU CRX BPTF GTF2A1 CPHXL ASCL1 NFYC CCAR1 ZNF853 PRDM15 MED12 EP300

7.17e-04145910718GO:0000977
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 SMG6

8.30e-041361075GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 SMG6

8.30e-041361075GO:0004519
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

TFEB NCOA3 RELA RFXAP TFDP2 CRX KMT2D NFYC PRDM15 NOTCH1

8.54e-0456010710GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

TFEB NCOA3 RELA RFXAP TFDP2 CRX KMT2D NFYC PRDM15 NOTCH1

9.26e-0456610710GO:0001216
GeneOntologyMolecularFunctionstructural molecule activity

ERVK-6 COL11A2 PNN ERVK-7 ERVK-21 ERVK-9 ERVK-10 EFEMP1 ERVK-8 MACF1 ERVK-19 BSN ERVK-24

9.55e-0489110713GO:0005198
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

NCOA3 KAT6A RELA ARID1A ZFPM2 CRX GTF2A1 ASCL1 MED12 EP300

1.14e-0358210710GO:0140297
GeneOntologyMolecularFunctionRNA polymerase II complex binding

NCOA3 HNRNPU SCAF4

1.19e-03391073GO:0000993
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 POLG ERVK-7 ERVK-10 ERVK-8

1.36e-031521075GO:0016779
GeneOntologyMolecularFunctionRNA polymerase II C-terminal domain binding

HNRNPU SCAF4

1.52e-03111072GO:0099122
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 POLG ERVK-7 ERVK-10 ERVK-8 SMG6

1.54e-032311076GO:0004518
GeneOntologyMolecularFunctionRNA polymerase core enzyme binding

NCOA3 HNRNPU SCAF4

1.80e-03451073GO:0043175
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

NCOA3 RELA ARID1A ZFPM2 CRX GTF2A1 MED12 EP300

1.82e-034171078GO:0061629
GeneOntologyMolecularFunctionmiRNA binding

YBX1 PUM2 PUM1

2.17e-03481073GO:0035198
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24

2.21e-034301078GO:0004175
GeneOntologyMolecularFunctionAP-2 adaptor complex binding

BMP2K AAK1

2.48e-03141072GO:0035612
GeneOntologyMolecularFunctionhistone acetyltransferase activity

NCOA3 KAT6A EP300

2.58e-03511073GO:0004402
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

KAT6A EP300

2.85e-03151072GO:0010484
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

TFEB SP4 RELA HNRNPU CRX BPTF CPHXL ASCL1 NFYC CCAR1 ZNF853 PRDM15 MED12 EP300 NOTCH1

3.16e-03127110715GO:0000987
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

NCOA3 KAT6A EP300

3.21e-03551073GO:0061733
GeneOntologyMolecularFunctionprotein antigen binding

EP400 EP300

3.25e-03161072GO:1990405
GeneOntologyMolecularFunctionnuclear receptor binding

NCOA3 ARID1A CRX MED12 EP300

3.36e-031871075GO:0016922
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

NCOA3 KAT6A EP300

4.10e-03601073GO:0034212
GeneOntologyMolecularFunctionMHC class I receptor activity

LILRB3 MFSD6

4.12e-03181072GO:0032393
GeneOntologyMolecularFunctionnuclear receptor coactivator activity

NCOA3 CCAR1 MED12

4.30e-03611073GO:0030374
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

ERVK-6 MAK BMP2K POLG AAK1 ERVK-7 ALPK1 ERVK-10 WNK1 EFEMP1 NRK ERVK-8

4.42e-0393810712GO:0016772
GeneOntologyMolecularFunctionregulatory RNA binding

YBX1 PUM2 PUM1

4.50e-03621073GO:0061980
GeneOntologyMolecularFunctionpre-mRNA binding

HNRNPU CELF3 EP300

4.92e-03641073GO:0036002
GeneOntologyMolecularFunctiongeneral transcription initiation factor binding

RELA HNRNPU GTF2A1

4.92e-03641073GO:0140296
GeneOntologyMolecularFunctionRNA polymerase binding

NCOA3 HNRNPU SCAF4

5.14e-03651073GO:0070063
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

NCOA3 EP300

5.59e-03211072GO:0042975
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

TFEB SP4 RELA HNRNPU CRX BPTF CPHXL ASCL1 NFYC CCAR1 ZNF853 PRDM15 MED12 EP300

6.58e-03124410714GO:0000978
GeneOntologyMolecularFunctionhistone H4 acetyltransferase activity

KAT6A EP300

6.69e-03231072GO:0010485
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

TET2 TFEB NCOA3 YBX1 RELA RFXAP TFDP2 ZFPM2 HNRNPU CRX BPTF GTF2A1 BMP6 TSC22D1 KMT2D GABPB2 ASCL1 NFYC MED12L SMARCA2 PRDM15 MED12 EP300 NOTCH1

2.41e-07139011024GO:0045944
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 ERVK-8

5.28e-07131104GO:0015074
GeneOntologyBiologicalProcessnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

YBX1 CPEB3 HNRNPU TOB1 DCP1B TNRC6A

1.28e-06651106GO:0000288
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-6 ERVK-7 ERVK-10 HNRNPU ERVK-8 SMG6

5.42e-06831106GO:0006278
GeneOntologyBiologicalProcessnuclear-transcribed mRNA catabolic process

YBX1 CPEB3 HNRNPU TOB1 DCP1B TNRC6A SMG6

6.90e-061321107GO:0000956
GeneOntologyBiologicalProcesspositive regulation of mRNA metabolic process

YBX1 CPEB3 PUM2 HNRNPU TOB1 DCP1B CELF3 TNRC6A PUM1

1.04e-052591109GO:1903313
GeneOntologyBiologicalProcessregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

YBX1 CPEB3 HNRNPU TOB1

1.22e-05271104GO:1900151
GeneOntologyBiologicalProcessmRNA destabilization

YBX1 CPEB3 PUM2 HNRNPU TOB1 DCP1B TNRC6A PUM1

1.48e-052061108GO:0061157
GeneOntologyBiologicalProcessRNA destabilization

YBX1 CPEB3 PUM2 HNRNPU TOB1 DCP1B TNRC6A PUM1

1.76e-052111108GO:0050779
GeneOntologyBiologicalProcesspositive regulation of mRNA catabolic process

YBX1 CPEB3 PUM2 HNRNPU TOB1 DCP1B TNRC6A PUM1

1.76e-052111108GO:0061014
GeneOntologyBiologicalProcessRNA localization

ERVK-6 YBX1 PUM2 ERVK-21 NUP42 WNK1 HNRNPU SMG6

2.15e-052171108GO:0006403
GeneOntologyBiologicalProcessnegative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

YBX1 HNRNPU TOB1

3.14e-05121103GO:1900152
GeneOntologyBiologicalProcesspositive regulation of nuclear-transcribed mRNA poly(A) tail shortening

CPEB3 TOB1 TNRC6A

5.15e-05141103GO:0060213
GeneOntologyBiologicalProcesspons development

CACNA1A ASCL1 SEC24B

6.41e-05151103GO:0021548
GeneOntologyBiologicalProcessregulation of nuclear-transcribed mRNA poly(A) tail shortening

CPEB3 TOB1 TNRC6A

7.86e-05161103GO:0060211
GeneOntologyBiologicalProcessmusculoskeletal movement, spinal reflex action

CACNA1A ASCL1

8.43e-0531102GO:0050883
GeneOntologyBiologicalProcessvestibular nucleus development

CACNA1A ASCL1

8.43e-0531102GO:0021750
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

9.20e-05851105GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

9.20e-05851105GO:0000768
GeneOntologyBiologicalProcessconnective tissue development

COL11A2 PUM2 CASR RELA BMP6 EFEMP1 GLG1 EP300 NOTCH1

9.31e-053431109GO:0061448
GeneOntologyBiologicalProcessregulation of cell division

CCP110 NCOA3 YBX1 MAP10 WNK1 KIF20A PRDM15

1.03e-042011107GO:0051302
GeneOntologyBiologicalProcesssyncytium formation

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

1.14e-04891105GO:0006949
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-7 ERVK-10 ERVK-8

1.24e-04481104GO:0000731
GeneOntologyBiologicalProcess3'-UTR-mediated mRNA destabilization

CPEB3 PUM2 PUM1

1.34e-04191103GO:0061158
GeneOntologyBiologicalProcessregulation of termination of RNA polymerase II transcription

WNK1 SCAF4

1.68e-0441102GO:1904594
GeneOntologyBiologicalProcessDNA biosynthetic process

ERVK-6 POLG ERVK-7 ERVK-10 HNRNPU ERVK-8 SMG6

1.69e-042181107GO:0071897
GeneOntologyBiologicalProcessregulation of mRNA stability

YBX1 CPEB3 PUM2 HNRNPU TOB1 DCP1B TNRC6A PUM1

1.72e-042921108GO:0043488
GeneOntologyBiologicalProcessmRNA catabolic process

YBX1 CPEB3 PUM2 HNRNPU TOB1 DCP1B TNRC6A PUM1 SMG6

1.75e-043731109GO:0006402
GeneOntologyBiologicalProcesspositive regulation of Notch signaling pathway

BMP2K AAK1 ASCL1 NOTCH1

1.83e-04531104GO:0045747
GeneOntologyBiologicalProcessviral process

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24 EP300 NOTCH1

1.90e-0446411010GO:0016032
GeneOntologyBiologicalProcessregulation of RNA stability

YBX1 CPEB3 PUM2 HNRNPU TOB1 DCP1B TNRC6A PUM1

2.48e-043081108GO:0043487
GeneOntologyBiologicalProcessregulation of mRNA catabolic process

YBX1 CPEB3 PUM2 HNRNPU TOB1 DCP1B TNRC6A PUM1

2.53e-043091108GO:0061013
GeneOntologyBiologicalProcessregulation of chondrocyte differentiation

RELA BMP6 EFEMP1 GLG1

2.78e-04591104GO:0032330
GeneOntologyBiologicalProcessmitral valve formation

ZFPM2 NOTCH1

2.79e-0451102GO:0003192
GeneOntologyBiologicalProcessmedulla oblongata development

CACNA1A ASCL1

2.79e-0451102GO:0021550
GeneOntologyBiologicalProcessnucleobase-containing compound catabolic process

YBX1 CPEB3 PUM2 NUDT17 HNRNPU TOB1 DCP1B TNRC6A PDE5A PUM1 EP300 SMG6

3.40e-0469611012GO:0034655
GeneOntologyBiologicalProcessRNA transport

ERVK-6 YBX1 ERVK-21 NUP42 WNK1 SMG6

3.54e-041751106GO:0050658
GeneOntologyBiologicalProcessnucleic acid transport

ERVK-6 YBX1 ERVK-21 NUP42 WNK1 SMG6

3.54e-041751106GO:0050657
GeneOntologyBiologicalProcessestablishment of RNA localization

ERVK-6 YBX1 ERVK-21 NUP42 WNK1 SMG6

3.87e-041781106GO:0051236
GeneOntologyBiologicalProcessDNA-templated DNA replication

ERVK-6 POLG ERVK-7 ERVK-10 ERVK-8 CIZ1

3.87e-041781106GO:0006261
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

NCOA3 UBQLN1 PUM2 RELA ALPK1 ARID1A KMT2D PUM1 EP300

3.91e-044161109GO:0030522
GeneOntologyBiologicalProcessregulation of termination of DNA-templated transcription

WNK1 SCAF4

4.17e-0461102GO:0031554
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

YBX1 KAT6A CPEB3 RELA ARID1A TFDP2 ZFPM2 HNRNPU SCAF4 BPTF PHC3 BMP6 TOB1 ASCL1 SMARCA2 CCAR1 EP300 NOTCH1

4.20e-04139911018GO:0045892
GeneOntologyBiologicalProcessspinal cord development

CACNA1A DCTN1 ASCL1 MED12 NOTCH1

4.44e-041191105GO:0021510
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

YBX1 KAT6A CPEB3 RELA ARID1A TFDP2 ZFPM2 HNRNPU SCAF4 BPTF PHC3 BMP6 TOB1 ASCL1 SMARCA2 CCAR1 EP300 NOTCH1

4.72e-04141311018GO:1902679
GeneOntologyBiologicalProcessRNA catabolic process

YBX1 CPEB3 PUM2 HNRNPU TOB1 DCP1B TNRC6A PUM1 SMG6

5.13e-044321109GO:0006401
GeneOntologyBiologicalProcessregulation of mRNA metabolic process

YBX1 CPEB3 PUM2 HNRNPU TOB1 DCP1B CELF3 TNRC6A PUM1

6.14e-044431109GO:1903311
GeneOntologyBiologicalProcessnuclear-transcribed mRNA poly(A) tail shortening

CPEB3 TOB1 TNRC6A

7.17e-04331103GO:0000289
GeneOntologyBiologicalProcessnegative regulation of stem cell differentiation

NCOA3 HNRNPU NOTCH1

7.17e-04331103GO:2000737
GeneOntologyBiologicalProcesschondrocyte differentiation

COL11A2 RELA BMP6 EFEMP1 GLG1

7.36e-041331105GO:0002062
GeneOntologyBiologicalProcesscoronary vasculature morphogenesis

ZFPM2 SEC24B NOTCH1

7.83e-04341103GO:0060977
GeneOntologyBiologicalProcessDNA-templated transcription termination

WNK1 SCAF4 LIPE

7.83e-04341103GO:0006353
GeneOntologyBiologicalProcessembryonic organ development

TFEB NCOA3 KAT6A ARID1A ZFPM2 BPTF NRK SEC24B MED12 NOTCH1

8.40e-0456111010GO:0048568
GeneOntologyBiologicalProcessnucleic acid catabolic process

YBX1 CPEB3 PUM2 HNRNPU TOB1 DCP1B TNRC6A PUM1 SMG6

8.53e-044641109GO:0141188
GeneOntologyBiologicalProcessprotein-DNA complex organization

TET2 NCOA3 EP400 KAT6A CHD9 RELA ARID1A EMSY HNRNPU BPTF GTF2A1 KMT2D SMARCA2 EP300

8.61e-0499911014GO:0071824
GeneOntologyBiologicalProcessregulation of chromosome segregation

PUM2 ARID1A HNRNPU SMARCA2 PUM1

8.98e-041391105GO:0051983
GeneOntologyBiologicalProcessregulation of cartilage development

RELA BMP6 EFEMP1 GLG1

9.29e-04811104GO:0061035
GeneOntologyBiologicalProcesschromatin organization

TET2 NCOA3 EP400 KAT6A CHD9 RELA ARID1A EMSY HNRNPU BPTF KMT2D SMARCA2 EP300

9.71e-0489611013GO:0006325
GeneOntologyBiologicalProcessatrioventricular valve formation

ZFPM2 NOTCH1

9.90e-0491102GO:0003190
GeneOntologyBiologicalProcessregulation of cytoplasmic translation

YBX1 CPEB3 HNRNPU

1.00e-03371103GO:2000765
GeneOntologyCellularComponentnuclear protein-containing complex

NCOA3 EP400 PNN YBX1 RELA NUP42 ARID1A RFXAP TFDP2 HNRNPU CRX BPTF GTF2A1 PHC3 KMT2D ASCL1 NFYC MED12L SMARCA2 SAGE1 MED12 SMG6

2.08e-06137710922GO:0140513
GeneOntologyCellularComponentRNA polymerase II transcription regulator complex

NCOA3 RFXAP TFDP2 HNRNPU CRX GTF2A1 ASCL1 NFYC

9.06e-052721098GO:0090575
GeneOntologyCellularComponenttranscription regulator complex

TFEB NCOA3 RELA RFXAP TFDP2 HNRNPU CRX GTF2A1 ASCL1 NFYC EP300

2.83e-0459610911GO:0005667
GeneOntologyCellularComponentCRD-mediated mRNA stability complex

YBX1 HNRNPU

3.99e-0461092GO:0070937
GeneOntologyCellularComponentmitotic spindle

MAK MAP10 WNK1 DCTN1 TFDP2 HNRNPU

6.53e-042011096GO:0072686
DomainMediator_Med12

MED12L MED12

2.78e-052992IPR019035
DomainMed12

MED12L MED12

2.78e-052992PF09497
DomainMediator_Med12_LCEWAV

MED12L MED12

2.78e-052992IPR021990
DomainMediator_Med12_catenin-bd

MED12L MED12

2.78e-052992IPR021989
DomainPumilio_RNA-bd

PUM2 PUM1

2.78e-052992IPR033712
DomainMed12-PQL

MED12L MED12

2.78e-052992PF12144
DomainMed12-LCEWAV

MED12L MED12

2.78e-052992PF12145
DomainMed12

MED12L MED12

2.78e-052992SM01281
DomainPUM-HD

PUM2 PUM1

8.32e-053992IPR033133
DomainPUF

PUM2 PUM1

8.32e-053992PF00806
DomainPUM_HD

PUM2 PUM1

8.32e-053992PS50303
DomainPumilio_RNA-bd_rpt

PUM2 PUM1

1.66e-044992IPR001313
DomainHSA

EP400 SMARCA2

1.66e-044992SM00573
DomainSUZ

ARPP21 R3HDM2

1.66e-044992IPR024771
DomainSUZ

ARPP21 R3HDM2

1.66e-044992PS51673
DomainHSA

EP400 SMARCA2

1.66e-044992PS51204
DomainHSA_dom

EP400 SMARCA2

1.66e-044992IPR014012
DomainPUM

PUM2 PUM1

1.66e-044992PS50302
DomainHSA

EP400 SMARCA2

1.66e-044992PF07529
DomainPumilio

PUM2 PUM1

1.66e-044992SM00025
Domainzf-RING_9

RUBCNL PLEKHM3

2.75e-045992PF13901
DomainDUF4206

RUBCNL PLEKHM3

2.75e-045992SM01175
DomainZf-RING_9

RUBCNL PLEKHM3

2.75e-045992IPR025258
DomainSAP

RFFL HNRNPU CCAR1

3.05e-0425993PS50800
DomainSAP_dom

RFFL HNRNPU CCAR1

3.05e-0425993IPR003034
DomainBromodomain_CS

BPTF SMARCA2 EP300

3.44e-0426993IPR018359
DomainBRK

CHD9 SMARCA2

4.11e-046992SM00592
DomainNuc_rcpt_coact

NCOA3 EP300

4.11e-046992IPR009110
DomainBRK_domain

CHD9 SMARCA2

4.11e-046992IPR006576
DomainBRK

CHD9 SMARCA2

4.11e-046992PF07533
DomainSNF2_N

EP400 CHD9 SMARCA2

6.41e-0432993IPR000330
DomainSNF2_N

EP400 CHD9 SMARCA2

6.41e-0432993PF00176
DomainR3H

ARPP21 R3HDM2

9.77e-049992SM00393
DomainBROMODOMAIN_1

BPTF SMARCA2 EP300

9.85e-0437993PS00633
DomainBromodomain

BPTF SMARCA2 EP300

1.07e-0338993PF00439
DomainZnf_FYVE_PHD

KAT6A RFFL BPTF KMT2D BSN

1.11e-03147995IPR011011
DomainBROMODOMAIN_2

BPTF SMARCA2 EP300

1.33e-0341993PS50014
DomainBROMO

BPTF SMARCA2 EP300

1.43e-0342993SM00297
DomainBromodomain

BPTF SMARCA2 EP300

1.43e-0342993IPR001487
Domain-

BPTF SMARCA2 EP300

1.43e-03429931.20.920.10
DomainR3H

ARPP21 R3HDM2

1.48e-0311992PS51061
DomainR3H

ARPP21 R3HDM2

1.48e-0311992PF01424
Domain-

ARPP21 R3HDM2

1.48e-03119923.30.1370.50
DomainR3H_dom

ARPP21 R3HDM2

1.48e-0311992IPR001374
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

RELA EP300 NOTCH1

1.00e-058813M48024
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

KAT6A ARID1A SMARCA2 EP300 NOTCH1

3.49e-0565815M39682
PathwayREACTOME_ADIPOGENESIS

NCOA3 CHD9 RELA HNRNPU MED12 EP300

3.97e-05110816M48259
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

TFEB EP400 RELA HNRNPU KMT2D SMARCA2 MED12 EP300 NOTCH1

5.55e-05301819MM15983
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

ARID1A PHC3 SMARCA2 EP300

5.78e-0537814M27797
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

NUMBL RELA ASCL1 EP300 NOTCH1

1.07e-0482815MM15922
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

NCOA3 CHD9 RELA MED12 EP300

1.20e-0484815M1008
PathwayBIOCARTA_VDR_PATHWAY

NCOA3 ARID1A EP300

2.60e-0422813MM1370
Pubmed

cDNAs with long CAG trinucleotide repeats from human brain.

NCOA3 EP400 NUMBL KMT2D CELF3 TNRC6A MED12

6.54e-132311179225980
Pubmed

Human transcription factor protein interaction networks.

TET2 NCOA3 EP400 PNN YBX1 PUM2 R3HDM2 RELA ARID1A RFXAP EMSY TFDP2 ZFPM2 SCAF4 BPTF PHC3 KMT2D DCP1B SEC24B TNRC6A NFYC SMARCA2 CCAR1 PUM1 EP300

2.81e-1214291112535140242
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10 ERVK-24

9.83e-114111410469592
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

2.35e-1012111514557543
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-21 ERVK-19

4.90e-105111412629516
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-24

7.39e-1094111821542922
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

TFEB NCOA3 SP4 RELA NUP42 ARID1A TFDP2 CRX BPTF GTF2A1 TSC22D1 CPHXL CIZ1 NFYC SMARCA2 CCAR1

6.51e-098081111620412781
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOA3 EP400 ARID1A BPTF KMT2D SMARCA2 EP300

9.47e-0983111728794006
Pubmed

Interaction network of human early embryonic transcription factors.

TET2 NCOA3 EP400 ARID1A EMSY CRX BPTF KMT2D SMARCA2 MED12 EP300

1.82e-083511111138297188
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

TET2 NCOA3 PUM2 R3HDM2 GTF2A1 TNRC6A CIZ1 EP300

3.34e-08152111838360978
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

EP400 KAT6A ARID1A BPTF PHC3 KMT2D SMARCA2 EP300

4.29e-08157111830186101
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

UBQLN1 EP400 BMP2K NUMBL AAK1 PUM2 RELA EMSY SCAF4 PHC3 GLG1 SEC24B TNRC6A CIZ1 SMARCA2 CCAR1 MACF1 LIMCH1 MED12 SMG6

5.34e-0814971112031527615
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

TET2 NCOA3 EP400 ARID1A ZFPM2 PHC3 KMT2D CIZ1 NFYC SMARCA2 EP300

6.53e-083981111135016035
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TET2 NCOA3 SP4 UBQLN1 EP400 YBX1 CHD9 ARID1A EMSY HNRNPU SCAF4 BPTF KMT2D SMARCA2 CCAR1 MED12 EP300

8.13e-0811031111734189442
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-10 ERVK-19

1.26e-07411137983737
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

WBP1 SP4 UBQLN1 EP400 WNK1 IVL PHC3 TOB1 SGCE BSN NOTCH1

1.42e-074301111135044719
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NCOA3 EP400 PNN AAK1 PUM2 RFFL EMSY SCAF4 BPTF PHC3 KMT2D SMARCA2 CCAR1 LIMCH1

1.87e-077741111415302935
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

TFEB CCP110 NCOA3 BMP2K NUMBL YBX1 AAK1 RELA ALPK1 WNK1 KIF20A DCP1B SEC24B LIMCH1 PUM1 MED12

2.03e-0710381111626673895
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

EP400 PNN ARID1A DCTN1 EMSY SCAF4 BPTF KMT2D SEC24B CIZ1 MED12 EP300

2.03e-075491111238280479
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

TET2 NCOA3 EP400 PNN ARID1A EMSY KMT2D SMARCA2 MED12

2.13e-07268111933640491
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

PNN AAK1 EMSY HNRNPU SCAF4 BPTF SEC24B DEF6 CCAR1 MACF1

2.54e-073601111033111431
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-10 ERVK-24

2.90e-0718111418664271
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

EP400 PNN NUMBL AAK1 PUM2 WNK1 DCTN1 EMSY HNRNPU SCAF4 GTF2A1 PHC3 SEC24B CIZ1 MACF1

3.01e-079341111533916271
Pubmed

Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor.

ASCL1 EP300 NOTCH1

3.15e-075111311564735
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

CCP110 NCOA3 EP400 YBX1 ARID1A ZFPM2 KIF20A BPTF KMT2D TNRC6A CCAR1

3.36e-074691111127634302
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-9 ERVK-19

6.28e-076111315063128
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

NCOA3 EP400 ARID1A EMSY BPTF KMT2D MED12

1.16e-06167111720362541
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

PNN NUP42 ARID1A GTF2A1 SEC24B TNRC6A TMEM131L MACF1

2.17e-06263111834702444
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

NCOA3 PUM2 NUP42 ARID1A KMT2D DCP1B TNRC6A SMARCA2 PUM1 EP300

2.20e-064571111032344865
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TFEB EP400 POLG KAT6A ARID1A WNK1 DCTN1 PLEKHG5 KMT2D DEF6 PUM1 MED12 EP300 NOTCH1 SMG6

2.43e-0611051111535748872
Pubmed

Genetic interaction mapping in mammalian cells using CRISPR interference.

EP400 ARID1A PHC3 KMT2D MED12

2.89e-0669111528481362
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-21 ERVK-19

3.74e-0610111312970426
Pubmed

A human MAP kinase interactome.

RELA NUP42 WNK1 DCTN1 GTF2A1 TSC22D1 TNRC6A NFYC MACF1 EP300

3.79e-064861111020936779
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TET2 TFEB CCP110 NUMBL AAK1 ALPK1 WNK1 DCP1B SEC24B MACF1 PLEKHM3 LIMCH1 PUM1

3.86e-068611111336931259
Pubmed

Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation.

RELA GTF2A1 EP300

5.12e-0611111310454579
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

NCOA3 ARID1A KMT2D SMARCA2 CCAR1 MED12 EP300

7.16e-06220111735785414
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

EP400 YBX1 PUM2 ARID1A ZFPM2 BPTF SMARCA2 CCAR1 EP300

7.20e-06411111935182466
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

EP400 PUM2 ARID1A EMSY BPTF PUM1

7.78e-06146111623892456
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

TET2 TFEB ARID1A TFDP2 SCAF4 BPTF GTF2A1 TNRC6A PUM1 SMG6

8.91e-065361111015840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

TET2 TFEB ARID1A TFDP2 SCAF4 BPTF GTF2A1 TNRC6A PUM1 SMG6

9.21e-065381111010512203
Pubmed

Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling.

EFEMP1 NOTCH1

1.01e-052111222665268
Pubmed

Association of the CAG repeat polymorphism in mitochondrial polymerase gamma (POLG1) with male infertility: a case-control study in an Algerian population.

POLG MED12

1.01e-052111234077112
Pubmed

PUM2 regulates the formation of thoracic aortic dissection through EFEMP1.

PUM2 EFEMP1

1.01e-052111237062520
Pubmed

Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins.

PUM2 PUM1

1.01e-052111212459267
Pubmed

Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins.

PUM2 PUM1

1.01e-052111229165587
Pubmed

PUMILIO-mediated translational control of somatic cell cycle program promotes folliculogenesis and contributes to ovarian cancer progression.

PUM2 PUM1

1.01e-052111235507203
Pubmed

Bespoke RNA recognition by Pumilios.

PUM2 PUM1

1.01e-052111226517885
Pubmed

Mouse Pum1 and Pum2 genes, members of the Pumilio family of RNA-binding proteins, show differential expression in fetal and adult hematopoietic stem cells and progenitors.

PUM2 PUM1

1.01e-052111212667987
Pubmed

Hypermethylation of adjacent CpG sites is negatively correlated with the expression of lineage oncogene ASCL1 in pulmonary neuroendocrine tumors.

ASCL1 NOTCH1

1.01e-052111228621224
Pubmed

Scaffold/matrix attachment region elements interact with a p300-scaffold attachment factor A complex and are bound by acetylated nucleosomes.

HNRNPU EP300

1.01e-052111211909954
Pubmed

Characterization of four novel CAG repeat-containing cDNAs.

R3HDM2 KMT2D

1.01e-05211128595911
Pubmed

Characterization of LILRB3 and LILRA6 allelic variants in the Japanese population.

LILRB3 LILRA6

1.01e-052111233526815
Pubmed

A Quantitative and Predictive Model for RNA Binding by Human Pumilio Proteins.

PUM2 PUM1

1.01e-052111231078383
Pubmed

Principles of mRNA control by human PUM proteins elucidated from multimodal experiments and integrative data analysis.

PUM2 PUM1

1.01e-052111232753408
Pubmed

Synergistic association of Notch and NFκB signaling and role of Notch signaling in modulating epithelial to mesenchymal transition in colorectal adenocarcinoma.

RELA NOTCH1

1.01e-052111225257945
Pubmed

MOZ is fused to p300 in an acute monocytic leukemia with t(8;22).

KAT6A EP300

1.01e-052111210824998
Pubmed

Characterization of mammalian orthologues of the Drosophila osa gene: cDNA cloning, expression, chromosomal localization, and direct physical interaction with Brahma chromatin-remodeling complex.

ARID1A SMARCA2

1.01e-052111211318604
Pubmed

The roles of calcium-sensing receptor and calcium channel in osteogenic differentiation of undifferentiated periodontal ligament cells.

CACNA1A CASR

1.01e-052111224842051
Pubmed

Effects of PUMILIO1 and PUMILIO2 knockdown on cardiomyogenic differentiation of human embryonic stem cells culture.

PUM2 PUM1

1.01e-052111232437472
Pubmed

Small cell lung cancer, an epithelial to mesenchymal transition (EMT)-like cancer: significance of inactive Notch signaling and expression of achaete-scute complex homologue 1.

ASCL1 NOTCH1

1.01e-052111227785690
Pubmed

Notch1 expression, which is related to p65 Status, is an independent predictor of prognosis in colorectal cancer.

RELA NOTCH1

1.01e-052111221771876
Pubmed

Effects of Celastrol on growth inhibition of U937 leukemia cells through the regulation of the Notch1/NF-kappaB signaling pathway in vitro.

RELA NOTCH1

1.01e-052111220346213
Pubmed

Characterization of RNP Networks of PUM1 and PUM2 Post-Transcriptional Regulators in TCam-2 Cells, a Human Male Germ Cell Model.

PUM2 PUM1

1.01e-052111232316190
Pubmed

Identification of a conserved interface between PUF and CPEB proteins.

CPEB3 PUM2

1.01e-052111222496444
Pubmed

Distinct frequency patterns of LILRB3 and LILRA6 allelic variants in Europeans.

LILRB3 LILRA6

1.01e-052111236449053
Pubmed

Molecular determinants of CaV2.1 channel regulation by calcium-binding protein-1.

CACNA1A CASR

1.01e-052111221965686
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

1.01e-05211129060628
Pubmed

Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer.

PUM2 PUM1

1.01e-052111212771951
Pubmed

Alternate modes of cognate RNA recognition by human PUMILIO proteins.

PUM2 PUM1

1.01e-052111221397187
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

1.01e-05211129460924
Pubmed

FOG-2 competes with GATA-4 for transcriptional coactivator p300 and represses hypertrophic responses in cardiac myocytes.

ZFPM2 EP300

1.01e-052111215220332
Pubmed

Critical role of phosphorylation of serine 165 of YBX1 on the activation of NF-κB in colon cancer.

YBX1 RELA

1.01e-052111226318844
Pubmed

Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients.

LILRB3 LILRA6

1.01e-052111219617579
Pubmed

PUMILIO proteins promote colorectal cancer growth via suppressing p21.

PUM2 PUM1

1.01e-052111235338151
Pubmed

Family-wide Structural Analysis of Human Numb-Associated Protein Kinases.

BMP2K AAK1

1.01e-052111226853940
Pubmed

NCOA3, a new fusion partner for MOZ/MYST3 in M5 acute myeloid leukemia.

NCOA3 KAT6A

1.01e-052111217805331
Pubmed

Ultrasound induces cyclooxygenase-2 expression through integrin, integrin-linked kinase, Akt, NF-kappaB and p300 pathway in human chondrocytes.

RELA EP300

1.01e-052111217692505
Pubmed

Comparative analysis of mRNA targets for human PUF-family proteins suggests extensive interaction with the miRNA regulatory system.

PUM2 PUM1

1.01e-052111218776931
Pubmed

Somatic mutations in KMT2D and TET2 associated with worse prognosis in Epstein-Barr virus-associated T or natural killer-cell lymphoproliferative disorders.

TET2 KMT2D

1.01e-052111231311407
Pubmed

Diversity of the human LILRB3/A6 locus encoding a myeloid inhibitory and activating receptor pair.

LILRB3 LILRA6

1.01e-052111224096970
Pubmed

Tagging genes with cassette-exchange sites.

NCOA3 COL11A2 PUM2 SOCS7 BPTF MACF1 PUM1 SMG6

1.27e-05335111815741177
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNA1A NCOA3 NUMBL AAK1 DCTN1 EMSY HNRNPU CCAR1 PPP1R3F MACF1 LIMCH1 BSN SMG6

1.28e-059631111328671696
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

TFEB EP400 PNN ARID1A RFXAP EMSY HNRNPU SCAF4 KIF20A BPTF PHC3 KMT2D CIZ1 CCAR1 EP300

1.60e-0512941111530804502
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

TFEB CCP110 EP400 NUP42 ARID1A WNK1 EMSY TNRC6A MACF1 BSN

1.98e-055881111038580884
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NUMBL POLG KAT6A AAK1 CHD9 ARID1A HNRNPU BPTF TSC22D1 SMARCA2 CCAR1 MACF1 LIMCH1 PRDM15 EP300 SMG6

2.07e-0514891111628611215
Pubmed

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

NCOA3 SMARCA2 EP300

2.08e-0517111319183483
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

EP400 RELA ARID1A SCAF4 BPTF GTF2A1 SMARCA2 MACF1 MED12

2.15e-05472111938943005
Pubmed

Genome-scale RNAi screen for host factors required for HIV replication.

BMP2K AAK1 RELA WNK1 HNRNPU GTF2A1 GABPB2 TMEM131L

2.17e-05361111818976975
Pubmed

TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.

ARID1A SMARCA2 EP300

2.49e-0518111328068325
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

UBQLN1 NUMBL KAT6A R3HDM2 WNK1 ZFPM2 EFEMP1 CELF3 PUM1 NOTCH1

2.62e-056081111016713569
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

PNN PUM2 HNRNPU SEC24B TNRC6A CCAR1 PUM1

2.95e-05274111734244482
Pubmed

SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators.

RELA EP300

3.02e-053111211567019
Pubmed

Antagonistic and cooperative AGO2-PUM interactions in regulating mRNAs.

PUM2 PUM1

3.02e-053111230333515
Pubmed

The transcriptional co-activator p/CIP (NCoA-3) is up-regulated by STAT6 and serves as a positive regulator of transcriptional activation by STAT6.

NCOA3 EP300

3.02e-053111215145939
Pubmed

Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas.

KMT2D NOTCH1

3.02e-053111227566587
Pubmed

The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression.

KMT2D EP300

3.02e-053111237410700
Pubmed

Caveolin-1 mediates chemoresistance in cisplatin-resistant ovarian cancer cells by targeting apoptosis through the Notch-1/Akt/NF-κB pathway.

RELA NOTCH1

3.02e-053111226503358
Pubmed

Role of p300 in regulating neuronal nitric oxide synthase gene expression through nuclear factor-κB-mediated way in neuronal cells.

RELA EP300

3.02e-053111223811396
Pubmed

A novel function of human Pumilio proteins in cytoplasmic sensing of viral infection.

PUM2 PUM1

3.02e-053111225340845
Pubmed

The MN1 oncoprotein synergizes with coactivators RAC3 and p300 in RAR-RXR-mediated transcription.

NCOA3 EP300

3.02e-053111212569362
InteractionSOX9 interactions

NCOA3 EP400 ARID1A PHC3 KMT2D SMARCA2 MED12 EP300

3.51e-08971038int:SOX9
InteractionTLE3 interactions

TET2 NCOA3 ARID1A EMSY SCAF4 CRX PHC3 KMT2D TNRC6A CCAR1 SAGE1 EP300 NOTCH1

6.35e-0837610313int:TLE3
InteractionCRX interactions

TET2 NCOA3 SP4 EP400 ARID1A CRX KMT2D NFYC SMARCA2 MED12 EP300

7.37e-0825410311int:CRX
InteractionETS1 interactions

NCOA3 EP400 ARID1A EMSY BPTF KMT2D SMARCA2 EP300

1.98e-071211038int:ETS1
InteractionSOX7 interactions

TET2 NCOA3 ARID1A ZFPM2 KMT2D SMARCA2 EP300

2.06e-07821037int:SOX7
InteractionALG13 interactions

NCOA3 PUM2 R3HDM2 ARID1A KMT2D TNRC6A CCAR1 PUM1 EP300

4.15e-071831039int:ALG13
InteractionEYA4 interactions

TET2 NCOA3 AAK1 PUM2 R3HDM2 GTF2A1 SEC24B TNRC6A CIZ1 EP300

4.77e-0724310310int:EYA4
InteractionHNF1B interactions

TET2 NCOA3 EP400 ARID1A CRX BPTF KMT2D SMARCA2 EP300

5.70e-071901039int:HNF1B
InteractionFMR1 interactions

NCOA3 PNN NUMBL YBX1 KAT6A PUM2 EMSY ZFPM2 HNRNPU KIF20A MACF1 BSN PUM1 SMG6

5.88e-0753610314int:FMR1
InteractionMED23 interactions

EP400 PUM2 RELA EMSY TNRC6A NFYC MED12L MED12 EP300 NOTCH1

1.09e-0626610310int:MED23
InteractionGCM1 interactions

TET2 NCOA3 ARID1A KMT2D SMARCA2 EP300

1.30e-06681036int:GCM1
InteractionCPEB4 interactions

CPEB3 PUM2 R3HDM2 NUP42 DCP1B TNRC6A SMARCA2 PUM1

1.37e-061561038int:CPEB4
InteractionTBR1 interactions

TET2 NCOA3 ARID1A KIF20A KMT2D SMARCA2 EP300

1.84e-061131037int:TBR1
InteractionCELF1 interactions

PUM2 R3HDM2 NUP42 HNRNPU SCAF4 TNRC6A CIZ1 CCAR1 PUM1 NOTCH1

2.22e-0628810310int:CELF1
InteractionEGR2 interactions

TET2 NCOA3 EP400 ARID1A EMSY KMT2D SMARCA2 EP300

2.73e-061711038int:EGR2
InteractionSP7 interactions

TET2 NCOA3 EP400 PNN ARID1A SCAF4 KMT2D SMARCA2 CCAR1 EP300

3.60e-0630410310int:SP7
InteractionAGO1 interactions

YBX1 R3HDM2 RELA HNRNPU KIF20A TNRC6A PUM1 SMG6

4.52e-061831038int:AGO1
InteractionGATA3 interactions

NCOA3 ARID1A ZFPM2 SCAF4 KMT2D SMARCA2 CCAR1 EP300

5.30e-061871038int:GATA3
InteractionFHL2 interactions

SP4 EP400 BMP2K MAP10 WNK1 EMSY PHC3 TOB1 NFYC CCAR1 EP300

5.80e-0639610311int:FHL2
InteractionPBRM1 interactions

EP400 KAT6A ARID1A TULP2 CRX BPTF NFYC SMARCA2 NOTCH1

7.07e-062581039int:PBRM1
InteractionZYX interactions

CCP110 BMP2K AAK1 WNK1 DCP1B TNRC6A CCAR1 MACF1 LIMCH1 EP300

7.23e-0632910310int:ZYX
InteractionSOX10 interactions

NCOA3 ARID1A CRX KMT2D SMARCA2 EP300

7.69e-06921036int:SOX10
InteractionELF5 interactions

PNN ARID1A EMSY BPTF KMT2D SMARCA2 EP300

1.05e-051471037int:ELF5
InteractionHNF4A interactions

NCOA3 EP400 ARID1A RFXAP EMSY BPTF KMT2D SMARCA2 EP300

1.18e-052751039int:HNF4A
InteractionPABPC1 interactions

TET2 YBX1 KAT6A PUM2 CHD9 R3HDM2 HNRNPU KIF20A TOB1 DCP1B TNRC6A PUM1 EP300 SMG6

1.27e-0569910314int:PABPC1
InteractionTNRC6A interactions

R3HDM2 ARID1A WNK1 KIF20A DCP1B SEC24B TNRC6A PUM1 MED12

1.36e-052801039int:TNRC6A
InteractionCEBPA interactions

TET2 NCOA3 SP4 UBQLN1 EP400 PNN YBX1 CHD9 ARID1A EMSY HNRNPU SCAF4 BPTF KMT2D SMARCA2 CCAR1 MACF1 MED12 EP300

1.58e-05124510319int:CEBPA
InteractionBAG2 interactions

TFEB POLG AAK1 RELA WNK1 KIF20A BPTF PHC3 CIZ1 NFYC PUM1 MED12 EP300

1.71e-0562210313int:BAG2
InteractionSMAD3 interactions

NCOA3 YBX1 KAT6A RELA ARID1A CRX BPTF TOB1 NFYC EP300 NOTCH1

1.80e-0544710311int:SMAD3
InteractionERG interactions

TET2 NCOA3 ARID1A EMSY HNRNPU KMT2D SMARCA2 EP300

1.91e-052231038int:ERG
InteractionNFIX interactions

EP400 YBX1 ARID1A RFXAP EMSY BPTF KMT2D SMARCA2

2.17e-052271038int:NFIX
InteractionPAX8 interactions

TET2 NCOA3 ARID1A KMT2D SMARCA2 EP300

2.26e-051111036int:PAX8
InteractionCNOT1 interactions

MAK R3HDM2 NUP42 GTF2A1 TOB1 TNRC6A PUM1 NOTCH1 SMG6

2.68e-053051039int:CNOT1
InteractionETV4 interactions

NCOA3 ARID1A KMT2D SMARCA2 EP300

2.74e-05691035int:ETV4
InteractionTBXT interactions

NCOA3 ARID1A KMT2D SMARCA2 CCAR1 EP300

2.90e-051161036int:TBXT
InteractionYTHDF2 interactions

BMP2K PUM2 R3HDM2 DCTN1 HNRNPU DCP1B TNRC6A PUM1 SMG6

3.19e-053121039int:YTHDF2
InteractionE2F5 interactions

ARID1A TFDP2 KMT2D EP300

3.34e-05361034int:E2F5
InteractionNAA40 interactions

EP400 PNN NUMBL AAK1 PUM2 WNK1 DCTN1 EMSY HNRNPU SCAF4 GTF2A1 PHC3 SEC24B CIZ1 MACF1 LIMCH1

3.54e-0597810316int:NAA40
InteractionYWHAH interactions

TET2 TFEB CCP110 NCOA3 PNN NUMBL AAK1 R3HDM2 WNK1 DCTN1 PLEKHG5 DCP1B SEC24B MACF1 PLEKHM3 LIMCH1 PUM1

4.12e-05110210317int:YWHAH
InteractionHDAC1 interactions

TET2 EP400 RELA ARID1A DCTN1 EMSY ZFPM2 HNRNPU KIF20A BPTF KMT2D TNRC6A NFYC SMARCA2 MED12 EP300 NOTCH1

4.41e-05110810317int:HDAC1
InteractionNFIA interactions

NCOA3 ARID1A HNRNPU CRX KMT2D SMARCA2 EP300

5.12e-051881037int:NFIA
InteractionR3HDM2 interactions

ARPP21 PUM2 R3HDM2 SEC24B TNRC6A PUM1

5.27e-051291036int:R3HDM2
InteractionSMAP2 interactions

BMP2K NUMBL PUM2 R3HDM2 CRX SEC24B PUM1

5.30e-051891037int:SMAP2
InteractionFBXO42 interactions

TFEB CCP110 EP400 NUP42 ARID1A WNK1 TNRC6A MACF1

5.54e-052591038int:FBXO42
InteractionCXXC1 interactions

TET2 RELA KMT2D NFYC SMARCA2 EP300

5.99e-051321036int:CXXC1
InteractionWWTR1 interactions

EP400 PNN ARID1A DCTN1 EMSY BPTF KMT2D SEC24B EP300 NOTCH1

6.07e-0542210310int:WWTR1
InteractionMYOD1 interactions

NCOA3 EP400 ARID1A BPTF KMT2D SMARCA2 EP300

6.25e-051941037int:MYOD1
InteractionNUP35 interactions

NCOA3 PUM2 NUP42 ARID1A KMT2D DCP1B TNRC6A SMARCA2 PUM1 EP300

6.31e-0542410310int:NUP35
InteractionKLF5 interactions

TET2 NCOA3 EP400 ARID1A KMT2D SMARCA2 EP300

6.45e-051951037int:KLF5
InteractionIRF1 interactions

YBX1 RELA ARID1A SMARCA2 EP300

6.69e-05831035int:IRF1
InteractionPGR interactions

NCOA3 RELA ARID1A BPTF EP300

7.09e-05841035int:PGR
InteractionIRF4 interactions

NCOA3 ARID1A KMT2D SMARCA2 EP300

7.50e-05851035int:IRF4
InteractionCLTA interactions

TET2 BMP2K NUMBL YBX1 AAK1 WNK1 DCP1B SEC24B TNRC6A

7.93e-053511039int:CLTA
InteractionCDX2 interactions

PNN RELA BPTF SMARCA2 EP300

7.93e-05861035int:CDX2
InteractionFEV interactions

NCOA3 EP400 ARID1A EMSY PHC3 KMT2D EP300

8.31e-052031037int:FEV
InteractionNUP43 interactions

EP400 PNN CHD9 CCDC168 NUP42 ARID1A EMSY BPTF PHC3 KMT2D CIZ1 MED12

8.31e-0562510312int:NUP43
InteractionSP4 interactions

SP4 CRX GTF2A1 NFYC

8.90e-05461034int:SP4
InteractionSNRNP40 interactions

EP400 PNN KAT6A ARID1A EMSY SCAF4 KIF20A PHC3 CIZ1 CCAR1 SAGE1 MED12

9.94e-0563710312int:SNRNP40
InteractionTNRC6B interactions

KAT6A PUM2 R3HDM2 KIF20A DCP1B SEC24B TNRC6A PUM1

1.00e-042821038int:TNRC6B
InteractionNFIC interactions

TET2 NCOA3 RELA ARID1A CRX KMT2D SMARCA2

1.03e-042101037int:NFIC
InteractionCPEB1 interactions

YBX1 PUM2 R3HDM2 DCP1B TNRC6A PUM1

1.05e-041461036int:CPEB1
InteractionPAX6 interactions

NCOA3 EP400 ARID1A RFXAP BPTF KMT2D NFYC SMARCA2 EP300

1.09e-043661039int:PAX6
InteractionFOXI1 interactions

NCOA3 ARID1A KMT2D SMARCA2 EP300

1.09e-04921035int:FOXI1
InteractionGTSE1 interactions

BMP2K NUMBL AAK1 WNK1 DCTN1 SEC24B TNRC6A

1.19e-042151037int:GTSE1
InteractionZMYND11 interactions

EP400 PNN RELA EMSY SMARCA2

1.21e-04941035int:ZMYND11
InteractionTLX3 interactions

TET2 NCOA3 ARID1A TFDP2 CRX KMT2D SMARCA2 EP300

1.25e-042911038int:TLX3
InteractionAP2B1 interactions

CCP110 BMP2K NUMBL YBX1 AAK1 WNK1 KIF20A TNRC6A EP300

1.26e-043731039int:AP2B1
InteractionDPF3 interactions

RELA ARID1A CRX SMARCA2 EP300

1.27e-04951035int:DPF3
InteractionHDAC2 interactions

TET2 EP400 BMP2K RELA ARID1A WNK1 DCTN1 EMSY ZFPM2 HNRNPU KIF20A BPTF SMARCA2 EP300

1.28e-0486510314int:HDAC2
InteractionTOP3B interactions

TFEB EP400 YBX1 POLG KAT6A R3HDM2 ARID1A WNK1 DCTN1 PLEKHG5 HNRNPU KMT2D SEC24B DEF6 PUM1 MED12 EP300 NOTCH1 SMG6

1.49e-04147010319int:TOP3B
InteractionAR interactions

TET2 NCOA3 EP400 PNN RELA ARID1A EMSY HNRNPU KMT2D MED12L SMARCA2 CCAR1 LIMCH1 MED12 EP300

1.53e-0499210315int:AR
InteractionEIF4ENIF1 interactions

PUM2 R3HDM2 KIF20A DCP1B DEF6 TNRC6A PUM1 SMG6

1.54e-043001038int:EIF4ENIF1
InteractionLILRA6 interactions

LILRB3 LILRA6

1.54e-0441032int:LILRA6
InteractionFOXK2 interactions

KAT6A EMSY CRX BPTF KMT2D NFYC EP300

1.57e-042251037int:FOXK2
InteractionMKRN2 interactions

PUM2 R3HDM2 RELA NUP42 TNRC6A MACF1 PUM1 EP300 NOTCH1

1.59e-043851039int:MKRN2
InteractionMEF2C interactions

NCOA3 ASCL1 EP300 NOTCH1

1.67e-04541034int:MEF2C
InteractionKLF3 interactions

EP400 ARID1A EMSY BPTF KMT2D SMARCA2 EP300

1.71e-042281037int:KLF3
InteractionSAP18 interactions

NCOA3 PNN RELA ARID1A HNRNPU DEF6 SMARCA2 SMG6

1.72e-043051038int:SAP18
InteractionKLF4 interactions

NCOA3 RELA ARID1A KMT2D SMARCA2 EP300

1.73e-041601036int:KLF4
InteractionNANOG interactions

EP400 PUM2 RELA ARID1A EMSY BPTF SMARCA2 PUM1 MED12 EP300

1.78e-0448110310int:NANOG
InteractionCNOT9 interactions

CCP110 PUM2 R3HDM2 TOB1 TNRC6A TMEM131L PUM1

1.85e-042311037int:CNOT9
InteractionBRCA1 interactions

NCOA3 YBX1 CHD9 RELA ARID1A DCTN1 EMSY TULP2 HNRNPU KIF20A BPTF SEC24B TNRC6A SMARCA2 SAGE1 MED12 EP300

1.90e-04124910317int:BRCA1
InteractionPPP1R12C interactions

CACNA1A KIF20A SMARCA2 MACF1

2.21e-04581034int:PPP1R12C
InteractionSMG7 interactions

NCOA3 R3HDM2 ARID1A KMT2D TNRC6A CCAR1 PUM1 SMG6

2.33e-043191038int:SMG7
InteractionEP300 interactions

NCOA3 UBQLN1 YBX1 KAT6A RELA ARID1A ZFPM2 HNRNPU SCAF4 CRX KMT2D ASCL1 SEC24B SMARCA2 BSN PUM1 EP300 NOTCH1

2.45e-04140110318int:EP300
InteractionUNK interactions

UBQLN1 YBX1 PUM2 ARID1A HNRNPU TSC22D1 TNRC6A LIMCH1 PUM1

2.45e-044081039int:UNK
InteractionTAF15 interactions

CACNA1A TET2 PNN ARID1A HNRNPU KIF20A CCAR1 MED12 EP300

2.45e-044081039int:TAF15
InteractionGATA1 interactions

ARID1A ZFPM2 KMT2D SMARCA2 CCAR1 EP300

2.48e-041711036int:GATA1
InteractionBARD1 interactions

PNN YBX1 KAT6A RELA TULP2 SCAF4 SMARCA2 CCAR1

2.54e-043231038int:BARD1
InteractionTLX1 interactions

NCOA3 KAT6A ARID1A KMT2D SMARCA2 EP300

2.80e-041751036int:TLX1
InteractionTEAD1 interactions

ARID1A CRX BPTF KMT2D SMARCA2 EP300

2.89e-041761036int:TEAD1
InteractionNFYC interactions

SP4 EP400 RFXAP EMSY CRX NFYC

2.98e-041771036int:NFYC
InteractionELF4 interactions

EP400 EMSY BPTF KMT2D SMARCA2

3.11e-041151035int:ELF4
InteractionKAT2A interactions

TFEB RELA CRX MED12 EP300 NOTCH1

3.26e-041801036int:KAT2A
InteractionSEC16A interactions

BMP2K R3HDM2 RELA DCTN1 KIF20A DCP1B SEC24B TNRC6A PUM1

3.37e-044261039int:SEC16A
InteractionKAT2B interactions

NCOA3 RELA HNRNPU NFYC SMARCA2 EP300 NOTCH1

3.46e-042561037int:KAT2B
InteractionCPAP interactions

CCP110 RELA DCTN1 DCP1B SEC24B TNRC6A

3.46e-041821036int:CPAP
InteractionHELZ interactions

PUM2 R3HDM2 NUP42 KIF20A DCP1B TNRC6A PUM1

3.54e-042571037int:HELZ
InteractionEED interactions

EP400 PNN BMP2K YBX1 ARID1A DCTN1 HNRNPU SCAF4 KIF20A BPTF PHC3 TSC22D1 NRK SEC24B SMARCA2 CCAR1 MACF1 LIMCH1

3.57e-04144510318int:EED
InteractionYWHAZ interactions

TET2 TFEB CCP110 NUMBL HS6ST2 KAT6A AAK1 R3HDM2 ARID1A WNK1 DCTN1 PLEKHG5 DCP1B MACF1 PLEKHM3 PUM1 EP300

3.59e-04131910317int:YWHAZ
GeneFamilyAtaxins|Trinucleotide repeat containing

NCOA3 EP400 NUMBL KMT2D CELF3 TNRC6A MED12

2.27e-1225647775
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA3 KAT6A EP300

2.78e-0517643486
GeneFamilyZinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases

KAT6A ZFPM2

1.43e-031664266
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

NCOA3 EP400 PNN YBX1 KAT6A AAK1 PUM2 ARID1A WNK1 HNRNPU BPTF PHC3 KMT2D GLG1 DEF6 SMARCA2 TMEM131L MACF1 EP300 NOTCH1

1.24e-06149210320M40023
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

NCOA3 KAT6A PUM2 CHD9 R3HDM2 BPTF SEC24B NFYC SMARCA2 LIMCH1 PUM1

2.29e-0646610311M13522
CoexpressionGSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN

TET2 POLG CHD9 WNK1 PHC3 TNRC6A MACF1

4.28e-061661037M6826
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

TET2 ARID1A WNK1 BPTF MED12L MACF1 EP300

7.29e-061801037M8239
CoexpressionGSE24726_WT_VS_E2_2_KO_PDC_DAY6_POST_DELETION_DN

CHD9 R3HDM2 WNK1 TFDP2 PHC3 PUM1 NOTCH1

1.45e-052001037M8056
CoexpressionIVANOVA_HEMATOPOIESIS_MATURE_CELL

CCP110 LILRB3 BMP2K AAK1 RFFL TFDP2 GTF2A1 GABPB2

2.37e-052981038M11205
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

NCOA3 KAT6A CPEB3 PUM2 CHD9 BPTF TMEM131L PUM1

2.49e-053001038M8702
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

NCOA3 BMP2K KAT6A PUM2 CHD9 R3HDM2 BPTF SEC24B NFYC SMARCA2 TMEM131L MACF1 PUM1

3.12e-0585610313M4500
CoexpressionPYEON_HPV_POSITIVE_TUMORS_UP

HNRNPU GABPB2 SMARCA2 PRDM15 NOTCH1

4.99e-051011035M7738
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN

TET2 CHD9 WNK1 HNRNPU TNRC6A SMARCA2 PUM1 NOTCH1 SMG6

9.57e-054671039M1347
CoexpressionENK_UV_RESPONSE_KERATINOCYTE_DN

NCOA3 KAT6A PUM2 WNK1 BPTF EFEMP1 SEC24B SMARCA2 MACF1

1.20e-044811039M3898
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN

TET2 CHD9 WNK1 HNRNPU TNRC6A SMARCA2 PUM1 NOTCH1 SMG6

1.25e-044841039MM999
CoexpressionGSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_DN

R3HDM2 TNFRSF10D ARID1A DEF6 MACF1 NOTCH1

1.30e-041971036M3193
CoexpressionGSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_UP

YBX1 RUBCNL TFDP2 HNRNPU GTF2A1 TMEM131L

1.38e-041991036M8035
CoexpressionGSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP

AAK1 DCTN1 LIPE MED12 EP300 NOTCH1

1.38e-041991036M7254
CoexpressionGSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP

BMP2K AAK1 PUM2 DCTN1 BPTF NOTCH1

1.38e-041991036M7259
CoexpressionGSE14350_TREG_VS_TEFF_IN_IL2RB_KO_UP

BMP2K PUM2 CHD9 RFFL PHC3 PPP1R3F

1.42e-042001036M3419
CoexpressionGSE18893_CTRL_VS_TNF_TREATED_TREG_2H_UP

BMP2K YBX1 AAK1 PHC3 GLG1 PDE5A

1.42e-042001036M7294
CoexpressionGSE6681_DELETED_FOXP3_VS_WT_TREG_DN

PUM2 RFXAP SCAF4 GLG1 PRDM15 NOTCH1

1.42e-042001036M6779
CoexpressionGSE17721_LPS_VS_CPG_1H_BMDC_DN

PNN RFFL GGT5 TSC22D1 SMARCA2 BSN

1.42e-042001036M3987
CoexpressionGSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_UP

TFEB UBQLN1 WNK1 ZFPM2 GGT5 BSN

1.42e-042001036M8853
CoexpressionSTARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP

SP4 NUMBL CHD9 WNK1 SMARCA2 BSN

1.66e-042061036M2817
CoexpressionSTARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP

SP4 NUMBL CHD9 WNK1 SMARCA2 BSN

1.75e-042081036MM581
CoexpressionTHAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_7DY_DN

LILRB3 PNN POLG AAK1 LILRA6 GABPB2 TMEM131L PUM1 EP300 NOTCH1

2.00e-0463410310M40866
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

NCOA3 MAK R3HDM2 ARID1A BPTF PUM1 SMG6

2.61e-071861037de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

NCOA3 MAK R3HDM2 ARID1A BPTF PUM1 SMG6

2.61e-0718610370b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KAT6A HNRNPU BPTF GLG1 SMARCA2 MACF1 PDE5A

3.02e-071901037d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K KAT6A CHD9 HNRNPU EFEMP1 MED12L MACF1

3.35e-0719310379c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PNN AAK1 HNRNPU BPTF PHC3 MACF1 SMG6

4.12e-071991037f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

KAT6A AAK1 PHC3 SMARCA2 TMEM131L MACF1

2.13e-061621036b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellcontrol-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RUBCNL CCDC168 MAP10 RFXAP CRX JHY

2.63e-061681036affc39c7568b7df4b36af6f5b0e3702a18b6268c
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1A CPEB3 KMT2D ASCL1 CELF3 JHY

4.17e-0618210361923932a9c60e9ec33db69ded441210d1fb07bec
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1A CPEB3 KMT2D ASCL1 CELF3 JHY

4.17e-06182103669ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TFEB HS6ST2 CPEB3 CASR NRK ST6GALNAC5

4.44e-061841036e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

CACNA1A CCP110 DCTN1 EMSY CIZ1 TMEM131L

4.44e-061841036ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CASR WNK1 TSC22D1 MED12L LIMCH1

5.02e-061881036bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K KAT6A CHD9 HNRNPU EFEMP1 MACF1

5.83e-06193103606b65110db974f4ef90d3511ff34428976a52c9c
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K KAT6A CHD9 HNRNPU EFEMP1 MACF1

5.83e-061931036a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K KAT6A CHD9 HNRNPU EFEMP1 MACF1

5.83e-061931036b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCOA3 MAK BMP2K RUBCNL CHD9 TMEM131L

6.01e-061941036d852aebf7a763b9a776c4570711f0c759f591910
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP2K KAT6A CHD9 GGT5 MED12L MACF1

6.19e-061951036a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

HS6ST2 PUM2 ARID1A WNK1 BPTF NOTCH1

6.95e-061991036358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellMyeloid-Myeloid-E_(Neutrophils)|Myeloid / shred on cell class and cell subclass (v4)

LILRB3 MFSD6 LILRA6 GGT5 MED12L

2.59e-0515010351bffb8d86b737ac43be902d9468041aef3542f1f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAK RUBCNL TTLL6 ASCL1 CELF3

3.86e-05163103599cf60dc87f7ce288553091bffcd85109a02bd8f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAK RUBCNL TTLL6 ASCL1 CELF3

3.86e-051631035510c0af66e82c5a8cf8edd0547dae4018a87dbbf
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RUBCNL CCDC168 CRX DEF6 MED12L

4.09e-0516510358b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCellcontrol-Myeloid-pDC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RUBCNL CCDC168 CRX DEF6 MED12L

4.09e-051651035243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A CASR ASCL1 CELF3 BSN

5.26e-051741035a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CPEB3 CASR BMP6 NRK

5.41e-051751035e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TET2 BMP2K WNK1 MED12L MACF1

5.41e-0517510351ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCellAdult-Epithelial-club_cell-D175|Adult / Lineage, Cell type, age group and donor

HS6ST2 CASR DCTN1 SOCS7 GGT5

5.71e-051771035d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CPEB3 CASR BMP6 NRK

5.86e-051781035dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CPEB3 CASR BMP6 NRK

5.86e-0517810354df6218b20c2f076c22346d23260964cc0d73e65
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAK HS6ST2 EFEMP1 PDE5A BSN

6.02e-051791035dcd0a83f0592ae27f814d064b4791f84c3c86e64
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CPEB3 CASR NRK ST6GALNAC5

6.51e-051821035041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCellwk_15-18-Epithelial-PNS-Early_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL11A2 HS6ST2 ASCL1 CELF3 BSN

6.68e-0518310357e8366ec8117d36cec67f77dcb0e9a6032d87fcb
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

COL11A2 HS6ST2 RUBCNL ASCL1 ST6GALNAC5

6.68e-051831035e0854864d377e158a4793088d1cb6b3dbf2c805d
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RUBCNL ASCL1 FAM186A CELF3 ST6GALNAC5

6.86e-0518410357aa245b73e10fd73d292e822de6b72920aa12355
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A CHD9 MACF1 PLEKHM3 EP300

6.86e-0518410351154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellmild-Myeloid-Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MAK RUBCNL ALPK1 BMP6 NOTCH1

6.86e-0518410351a0e8b20b3ac8416d05c2d5934ab4ac80be4cce5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CPEB3 CASR BMP6 NRK

7.22e-0518610351850583d23903d08226aeb0edb3e07b0994330e4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CPEB3 CASR BMP6 NRK

7.22e-0518610354dafc215c42e7949f932a3627359c107943b5d6b
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

BMP2K LILRA6 ALPK1 NUDT17 PRDM15

7.40e-0518710353c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCellPCW_05-06-Neuronal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HS6ST2 RUBCNL ASCL1 CELF3 ST6GALNAC5

7.40e-05187103503a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCellASK454-Epithelial-Type_1|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

SOCS7 EFEMP1 ST6GALNAC5 PPP1R3F LIMCH1

7.59e-05188103513f8ce8f24ac7d7ed87f4ae3b8f4096de29383c2
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

HS6ST2 CASR WNK1 NRK LIMCH1

7.59e-051881035df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CASR WNK1 TSC22D1 LIMCH1

7.59e-051881035eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CPEB3 CASR WNK1 NRK

7.78e-051891035f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CASR WNK1 NRK LIMCH1

7.78e-051891035975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CASR WNK1 NRK LIMCH1

7.78e-0518910357eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellwk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CACNA1A ASCL1 CELF3 ST6GALNAC5 BSN

7.98e-0519010355f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CPEB3 CASR WNK1 NRK

7.98e-051901035b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CPEB3 CASR NRK ST6GALNAC5

7.98e-051901035cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CASR WNK1 MED12L LIMCH1

7.98e-051901035e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TFEB HS6ST2 CPEB3 CASR NRK

8.18e-051911035963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

YBX1 ASCL1 ST6GALNAC5 TMEM131L PDE5A

8.18e-051911035509d17d8ee0d028757ce0f2c9b97e5875f06f0ab
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

NCOA3 PNN GLG1 TMEM131L MACF1

8.18e-0519110359454f642c3621370fa23640b631301346b300950
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HS6ST2 CASR ZFPM2 NRK SMARCA2

8.59e-05193103568089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCellB_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CACNA1A NCOA3 BMP2K RUBCNL BMP6

8.80e-05194103522b87fe2bb84632ddcef8f1d7742021728e2246d
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HS6ST2 CASR WNK1 TOB1 NRK

9.01e-0519510353123e02d2894c83962ba402085b5e6422ebf8c73
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARPP21 YBX1 TSC22D1 ASCL1 CELF3

9.23e-051961035fe2dd3a93fe22da93e24a400e154a68757985fc8
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

WNK1 HNRNPU TOB1 MACF1 PUM1

9.23e-051961035ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TET2 HS6ST2 RELA HNRNPU PUM1

9.46e-0519710355bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RUBCNL TFDP2 ASCL1 CELF3 NOTCH1

9.46e-0519710351378bf90a4b80b8166ef352c282ce51b114ba693
ToppCell368C-Fibroblasts-Fibroblast-G|368C / Donor, Lineage, Cell class and subclass (all cells)

TSC22D1 MACF1 PDE5A SGCE LIMCH1

9.46e-051971035156155c2f0c1a2461e45803da578af18ee221660
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PNN AAK1 HNRNPU SMARCA2 MACF1

9.46e-05197103557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellcontrol-Myeloid-Non-resident_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TET2 LILRB3 HNRNPU GABPB2 PUM1

9.46e-051971035df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCell368C-Fibroblasts-Fibroblast-G-|368C / Donor, Lineage, Cell class and subclass (all cells)

TSC22D1 MACF1 PDE5A SGCE LIMCH1

9.46e-051971035d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A ARPP21 CASR ASCL1 CELF3

9.69e-0519810358f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

YBX1 RUBCNL TFDP2 ASCL1 NOTCH1

9.69e-051981035e442692a8a5aad5b84eabbf051d32eae01b1069a
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A ARPP21 CASR ASCL1 CELF3

9.69e-051981035e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pre_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ARPP21 PNN RUBCNL TFDP2 TMEM131L

9.92e-051991035dd94e42b62af7cbd69c472681d3c758552694ae2
ToppCell10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-pre_B_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ARPP21 PNN RUBCNL TFDP2 TMEM131L

9.92e-051991035dadee9fc6ce4f4bdb19d29326889316443dda0cb
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GGT5 EFEMP1 NRK SGCE LIMCH1

9.92e-051991035e78f661b40da34768469549b6e755d330be6bbd8
ToppCellfacs-Brain_Non-Myeloid-Hippocampus|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCP110 UBQLN1 WNK1 DCTN1 HNRNPU

1.02e-042001035fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 PNN HNRNPU BPTF MACF1

1.02e-04200103512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCP110 UBQLN1 WNK1 DCTN1 HNRNPU

1.02e-042001035f0c338877e39226a90c4effe12f6501d33542a73
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

PNN R3HDM2 HNRNPU BPTF NRK

1.02e-0420010357c261e39ac30b318511373ab7302aa53b8b81b9c
Drugglutamin

CACNA1A NCOA3 UBQLN1 POLG KAT6A ARID1A DCTN1 CRX GGT5 GLG1 CELF3 CIZ1 EP300

1.86e-0746110413CID000000738
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A

KAT6A PUM2 CHD9 ARID1A SEC24B PUM1 EP300

1.91e-0518010474541_DN
DrugAC1O3GBZ

POLG RELA TNFRSF10D SMG6

2.16e-05361044CID006327751
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

PUM2 CHD9 ARID1A BPTF SEC24B TMEM131L PUM1

2.20e-0518410472321_DN
Drugtyrphostin AG-825; Down 200; 25.2uM; MCF7; HT_HG-U133A_EA

NCOA3 PUM2 CHD9 ARID1A BPTF SEC24B PUM1

2.28e-0518510471114_DN
DrugAmethopterin (R,S) [59-05-2]; Down 200; 8.8uM; HL60; HG-U133A

AAK1 ARID1A TFDP2 KIF20A BPTF SMARCA2 MACF1

2.90e-0519210471599_DN
DrugPropantheline bromide [50-34-0]; Up 200; 9uM; MCF7; HT_HG-U133A

CASR NUP42 SOCS7 CIZ1 PUM1 JHY SMG6

3.10e-0519410474798_UP
DrugVerapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; HL60; HG-U133A

ARID1A SCAF4 KIF20A BPTF CIZ1 SMARCA2 TMEM131L

3.10e-0519410472009_DN
DrugMepenzolate bromide [76-90-4]; Down 200; 9.6uM; PC3; HT_HG-U133A

TFEB AAK1 ARID1A WNK1 DCTN1 SCAF4 GLG1

3.41e-0519710473748_DN
DrugBumetanide [28395-03-1]; Up 200; 11uM; MCF7; HT_HG-U133A

POLG CASR BMP6 ASCL1 SMARCA2 MED12 SMG6

3.64e-0519910475542_UP
DrugNomifensine maleate [32795-47-4]; Up 200; 11.2uM; PC3; HT_HG-U133A

TFEB EMSY TFDP2 BMP6 LIMCH1 JHY SMG6

3.64e-0519910472062_UP
DrugTacrine hydrochloride hydrate [1684-40-8]; Down 200; 15.8uM; HL60; HT_HG-U133A

POLG AAK1 RELA DCTN1 TFDP2 CIZ1 EP300

3.76e-0520010471278_DN
DiseaseMalignant neoplasm of breast

NCOA3 YBX1 RELA NUDT17 ARID1A WNK1 EMSY CRX GTF2A1 KMT2D LIPE EFEMP1 NFYC MACF1 MED12 EP300 NOTCH1

1.37e-07107410117C0006142
DiseaseBreast Carcinoma

NCOA3 YBX1 RELA NUDT17 ARID1A EMSY KMT2D EFEMP1 MED12 EP300 NOTCH1

2.42e-0653810111C0678222
Diseasetestosterone measurement

TET2 TFEB HS6ST2 R3HDM2 ARID1A ZFPM2 CRX BMP6 LIPE ASCL1 FAM186A SMARCA2 MACF1 PLEKHM3 MED12 JHY

6.74e-06127510116EFO_0004908
DiseaseMammary Carcinoma, Human

NCOA3 YBX1 RELA NUDT17 EMSY KMT2D EFEMP1 MED12 EP300 NOTCH1

1.32e-0552510110C4704874
DiseaseMammary Neoplasms, Human

NCOA3 YBX1 RELA NUDT17 EMSY KMT2D EFEMP1 MED12 EP300 NOTCH1

1.32e-0552510110C1257931
DiseaseMammary Neoplasms

NCOA3 YBX1 RELA NUDT17 EMSY KMT2D EFEMP1 MED12 EP300 NOTCH1

1.36e-0552710110C1458155
DiseaseT-Cell Lymphoma

ARID1A KMT2D EP300

2.11e-05161013C0079772
DiseaseAdenoid Cystic Carcinoma

KAT6A ARID1A SMARCA2 EP300 NOTCH1

2.47e-051001015C0010606
Diseasefree androgen index

TET2 TFEB R3HDM2 ARID1A ZFPM2 ASCL1 SMARCA2 JHY

4.48e-053741018EFO_0007005
Diseaseobesity (implicated_via_orthology)

PUM2 BMP6 MED12L PUM1 MED12 NOTCH1

9.94e-052151016DOID:9970 (implicated_via_orthology)
DiseaseSezary Syndrome

TET2 ARID1A KMT2D

1.07e-04271013C0036920
DiseaseMalignant Cystosarcoma Phyllodes

KMT2D MED12

1.15e-0451012C0600066
DiseasePhyllodes Tumor

KMT2D MED12

1.15e-0451012C0010701
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

ARID1A SMARCA2

1.15e-0451012C3281201
DiseaseBladder Neoplasm

ARID1A BPTF KMT2D EP300 NOTCH1

1.23e-041401015C0005695
DiseaseMalignant neoplasm of urinary bladder

ARID1A BPTF KMT2D EP300 NOTCH1

1.27e-041411015C0005684
Diseasemonocyte count

TET2 LILRB3 BMP2K LILRA6 R3HDM2 WNK1 TFDP2 ZFPM2 GGT5 GLG1 MED12L TMEM131L PDE5A SMG6

1.62e-04132010114EFO_0005091
Diseaseleukocyte immunoglobulin-like receptor subfamily B member 3 measurement

LILRB3 LILRA6

1.72e-0461012EFO_0802705
Diseaseleukocyte immunoglobulin-like receptor subfamily A member 6 measurement

LILRB3 LILRA6

1.72e-0461012EFO_0801767
Diseaseprostate cancer (is_marker_for)

NCOA3 BMP6 KMT2D SMARCA2 EP300

2.04e-041561015DOID:10283 (is_marker_for)
Diseaselysosomal protective protein measurement

ZFPM2 TMEM131L

2.41e-0471012EFO_0008215
Diseaseneutrophil count

CACNA1A TET2 CHD9 ARID1A ZFPM2 IVL GTF2A1 GABPB2 GLG1 FAM186A DEF6 TNRC6A GRIN3B SMG6

2.59e-04138210114EFO_0004833
DiseaseNeoplasm of uncertain or unknown behavior of breast

ARID1A EP300 NOTCH1

3.78e-04411013C0496956
DiseaseBreast adenocarcinoma

ARID1A EP300 NOTCH1

3.78e-04411013C0858252
DiseaseMalignant mesothelioma

TFDP2 EFEMP1 SMARCA2 LIMCH1

5.46e-041091014C0345967
Diseasealcohol use disorder (implicated_via_orthology)

ARID1A CIZ1 SMARCA2 EP300 NOTCH1

5.68e-041951015DOID:1574 (implicated_via_orthology)
Diseaseapolipoprotein A 1 measurement

TET2 PUM2 R3HDM2 ARID1A ZFPM2 GTF2A1 ASCL1 DEF6 MACF1 SMG6

6.64e-0484810110EFO_0004614
DiseaseCoffin-Siris syndrome

ARID1A SMARCA2

8.83e-04131012C0265338
DiseaseConnective Tissue Diseases

COL11A2 NOTCH1

8.83e-04131012C0009782
DiseaseSquamous cell carcinoma

NCOA3 IVL EP300 NOTCH1

8.86e-041241014C0007137
Diseaseage at menarche

TET2 AAK1 ARID1A GABPB2 TNRC6A SMARCA2 BSN JHY

1.01e-035941018EFO_0004703
DiseaseMalignant neoplasm of skin

RELA IVL NOTCH1

1.10e-03591013C0007114
DiseaseSkin Neoplasms

RELA IVL NOTCH1

1.10e-03591013C0037286
Diseasemyelodysplastic syndrome (implicated_via_orthology)

TET2 POLG

1.18e-03151012DOID:0050908 (implicated_via_orthology)
Diseaseoral squamous cell carcinoma (is_marker_for)

TET2 RELA KMT2D

1.33e-03631013DOID:0050866 (is_marker_for)
Diseaselung non-small cell carcinoma (is_implicated_in)

TET2 RELA ARID1A KMT2D

1.35e-031391014DOID:3908 (is_implicated_in)
Diseasestomach cancer (is_marker_for)

TET2 ARID1A KMT2D SGCE

1.46e-031421014DOID:10534 (is_marker_for)
Diseasebreast carcinoma (is_marker_for)

NCOA3 KMT2D EP300

1.52e-03661013DOID:3459 (is_marker_for)
Diseaseesophagus squamous cell carcinoma (is_marker_for)

TET2 BMP6 KMT2D

2.12e-03741013DOID:3748 (is_marker_for)
Diseasecancer (implicated_via_orthology)

ARID1A PHC3 SMARCA2 MACF1 NOTCH1

2.32e-032681015DOID:162 (implicated_via_orthology)
DiseaseInfiltrating duct carcinoma of female breast

MAK NRK

2.33e-03211012C3165106
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

TET2 ARPP21 TFDP2 KMT2D TNRC6A BSN

2.51e-033981016EFO_0003756, EFO_0003888, EFO_0004337
DiseaseC-reactive protein measurement

TFEB ARPP21 R3HDM2 CCDC168 ZFPM2 SCAF4 BPTF ASCL1 MACF1 BSN ZNF853

2.80e-03120610111EFO_0004458
DiseaseColorectal Carcinoma

TET2 ARID1A WNK1 BMP6 EFEMP1 CCAR1 EP300 AMTN

2.86e-037021018C0009402
Diseasecongenital heart disease (is_implicated_in)

SP4 NOTCH1

3.05e-03241012DOID:1682 (is_implicated_in)
DiseaseCerebral Astrocytoma

NCOA3 NOTCH1

3.31e-03251012C0750935
DiseaseIntracranial Astrocytoma

NCOA3 NOTCH1

3.31e-03251012C0750936
DiseaseAstrocytoma

NCOA3 NOTCH1

3.31e-03251012C0004114
DiseaseGrade I Astrocytoma

NCOA3 NOTCH1

3.31e-03251012C1704230
DiseaseAtaxia

CACNA1A PUM1

3.31e-03251012C0004134
DiseaseSubependymal Giant Cell Astrocytoma

NCOA3 NOTCH1

3.31e-03251012C0205768
DiseaseMixed oligoastrocytoma

NCOA3 NOTCH1

3.31e-03251012C0547065
DiseasePilocytic Astrocytoma

NCOA3 NOTCH1

3.31e-03251012C0334583
DiseaseJuvenile Pilocytic Astrocytoma

NCOA3 NOTCH1

3.31e-03251012C0280783
DiseaseDiffuse Astrocytoma

NCOA3 NOTCH1

3.31e-03251012C0280785
DiseaseChildhood Cerebral Astrocytoma

NCOA3 NOTCH1

3.31e-03251012C0338070

Protein segments in the cluster

PeptideGeneStartEntry
AGGSGPPQQQQQQQQ

CACNA1A

2306

O00555
LNNQEQNGPIDPENN

SMG6

101

Q86US8
VQAKNQQNQQPGQSP

EP300

486

Q09472
QQPSNQGQFLPQTQF

EP300

756

Q09472
QRAGLPQQQPQQQLQ

EP300

2141

Q09472
VQVPQIQGQAQSPAQ

EP400

2791

Q96L91
QQQQQQQQREGPDGC

CELF3

366

Q5SZQ8
NQQEASVERQQQPPP

DCTN1

536

Q14203
QGLPAQAQATPQHQQ

AAK1

451

Q2M2I8
QQLQQPQQTLLTQPA

CCAR1

96

Q8IX12
QTLPNQNQSQTQPLL

CCAR1

206

Q8IX12
QEQQQQPLTLPQQQR

CASR

941

P41180
LAPDQGTLPNQQQSN

AMTN

31

Q6UX39
PPQQHRVLQQLQQGD

BMP2K

431

Q9NSY1
QPQSNVQGQSPVRVQ

BPTF

2456

Q12830
QQPPQSQNVINNQQG

ARPP21

696

Q9UBL0
QEPNNDNLEPSQNQP

ALPK1

651

Q96QP1
QQQQQQAASVAPVPT

NUMBL

441

Q9Y6R0
RGLLPCTAQQQQQQQ

R3HDM2

396

Q9Y2K5
QQQQQQQQLPALPPT

R3HDM2

406

Q9Y2K5
PQDVQQQPQDLQSQV

RUBCNL

56

Q9H714
QQPQDLQSQVPAAGN

RUBCNL

61

Q9H714
GQRPLTPNQGQQGQQ

PUM2

391

Q8TB72
PPQQQQQQPSTNLQS

PUM2

506

Q8TB72
QQQPQSQPPQLQSSQ

ARID1A

501

O14497
PSRYPPQQQQQQQQR

ARID1A

1321

O14497
NLQPANIQQQQSLQP

NOTCH1

2396

P46531
TQQERQQLQQPASQP

MAP10

211

Q9P2G4
RQLQKQLSSNQPQQG

MED12L

2121

Q86YW9
ASQGNQNNPPRQQQN

JHY

386

Q6NUN7
QESQQQLQARIQPNP

NUDT17

191

P0C025
ANPQQENISQNPQHE

ZFPM2

1056

Q8WW38
QLQGRQAAPGPQQSQ

BSN

3746

Q9UPA5
AASRQPQTQQQQQGL

BSN

3771

Q9UPA5
QPQLQLQSQSQPVLQ

PNN

481

Q9H307
PSFGQQRQQQQPQQQ

PDE5A

6

O76074
PATQQQQPQQQRGAA

HNRNPU

166

Q00839
PQNQQPHRAQRSPQQ

COL11A2

236

P13942
QQQQQPQQPQVLSSE

POLG

51

P54098
PQGQRLRQQLQQSQG

MED12

1906

Q93074
PQSQPQFQRQGLQQT

MED12

2131

Q93074
RQLQQQLSNTQPQPS

MED12

2156

Q93074
QRPGQQPQAGLSQAN

LILRA6

266

Q6PI73
QRPGQQPQAGLSQAN

LILRB3

266

O75022
TPLQQQQQQQPLLQG

PLEKHM3

166

Q6ZWE6
QQQQQPLLQGPHVTR

PLEKHM3

171

Q6ZWE6
QPLQGTNENRENSPA

MFSD6

721

Q6ZSS7
QPGPNLQQSTANQVQ

PHC3

431

Q8NDX5
QPTAVQVQGQQQGQQ

NFYC

151

Q13952
QSPTGEQIPQFQQRQ

MACF1

5591

Q9UPN3
GRQQPQQQPSGNNRR

NUP42

31

O15504
QTTPQAQQGQQQVLR

PUM1

491

Q14671
GGASQRPLTPNQNQQ

PUM1

506

Q14671
RPLTPNQNQQGQQTD

PUM1

511

Q14671
QSCVVERPPSNQQQQ

KAT6A

1636

Q92794
ENQQQRIPQPNQTLD

DCP1B

206

Q8IZD4
LSGNEQRGQPQAPQQ

ERVK-10

606

P87889
LSGNEQRGQPQAPQQ

ERVK-19

606

Q9YNA8
LSGNEQRGQPQAPQQ

ERVK-21

606

P62683
LSGNEQRGQPQAPQQ

ERVK-24

606

P63145
LSGNEQRGQPQAPQQ

ERVK-6

606

Q7LDI9
LSGNEQRGQPQAPQQ

ERVK-7

606

P63130
LSGNEQRGQPQAPQQ

ERVK-8

606

P62685
LSGNEQRGQPQAPQQ

ERVK-9

606

P63126
LSGNEQRGQPQAPQQ

HERVK_113

606

P62684
QQLPQLPQSSQLQQQ

GLG1

61

Q92896
QNRNNLNPGQNSLSQ

CHD9

181

Q3L8U1
PQQQQRQQQQPQPES

CPEB3

16

Q8NE35
QQQQQQQAPQLRPAA

ASCL1

56

P50553
QPQPPALRQQEEQQQ

BMP6

101

P22004
QRGLQDRGQNQTQRP

GGT5

541

P36269
QNPSETRVLQPNQGQ

CCP110

941

O43303
QGNRTPSPNSNEQQK

DEF6

591

Q9H4E7
QNLSVQQPPKQQSQE

MAK

351

P20794
SQNPNPNANQNLTQN

HS6ST2

546

Q96MM7
QQQTQQQVAQPSPVS

EMSY

416

Q7Z589
NQPGSTNIQVQPQTH

CCDC168

1591

Q8NDH2
QQAQAQGIPLTPQQA

FAM186A

1606

A6NE01
NVTPNTVNQQPGAQQ

SEC24B

101

O95487
DRDGRQQPPQQPQQQ

SCAF4

936

O95104
QQRQQQKQQQQPPGG

CRX

96

O43186
QSQLQSQLPQNNGKP

CPHXL

351

A0A1W2PPM1
NTQQKPASNQRPLTQ

LIPE

46

Q05469
GTNPQLAQDPSQNQQ

LIMCH1

931

Q9UPQ0
QLQQVPRGQNQRSQT

POM121L1P

406

Q3SYA9
QGQDQVPEQQRQGQA

NRK

521

Q7Z2Y5
VPEQQRQGQAPEQQQ

NRK

526

Q7Z2Y5
SGPEVEQQQQQQDQP

GRIN3B

901

O60391
EQQQQQQDQPTAPEG

GRIN3B

906

O60391
QIIVNNEQPQQETQP

EFEMP1

76

Q12805
QNQVNVNPERANPVT

GABPB2

161

Q8TAK5
PSQGLVQLQNQPQQL

SP4

76

Q02446
QQQQQQQQQLGGPPT

TFEB

36

P19484
PQTQQQQQPALVNYN

SMARCA2

246

P51531
PEISRKNNGNNQQVP

TMEM131L

1131

A2VDJ0
SVPPAQVQENQQANG

RFFL

186

Q8WZ73
PPQQAAQPQVQAEQQ

PRDM15

1486

P57071
NSIPGARPVLQQQQQ

NCOA3

966

Q9Y6Q9
GQKERPPQQQQQQQQ

ST6GALNAC5

31

Q9BVH7
NQQVLEQRQQQFPGT

RFXAP

256

O00287
NIGQQANIPTAVQQP

TSC22D1

731

Q15714
QQGQLEVPEQQVGQP

IVL

446

P07476
TQQNLPHQTQIPQQQ

SGCE

416

O43556
RQNEQQNQGPPALNS

TFDP2

256

Q14188
LSGNEQRGQPQAPQQ

ERVK-9

606

P63128
PQAHSQGPRQVQLQQ

CIZ1

381

Q9ULV3
QDEVPQQTVAPQQQR

TNFRSF10D

61

Q9UBN6
QPQQTVPQQAQTQQV

GTF2A1

91

P52655
NAQNQLQQLRAQEPP

PLEKHG5

681

O94827
GTNSQNQRINVQPLN

TULP2

411

O00295
NQGDETQGQQPPQRR

YBX1

266

P67809
ENDQPQPNNVLSTVQ

SAGE1

306

Q9NXZ1
GTNQENQQPNQQPPG

KIF20A

831

O95235
SRQPQPQNEQSPQRS

SPDYE5

21

A6NIY4
VNPQLQNPEVRFQQQ

UBQLN1

536

Q9UMX0
QQQQLPQLEPQPECQ

PPP1R3F

301

Q6ZSY5
RENPGAQNGLQNAQQ

TTLL6

36

Q8N841
PLGRLSRGEQQQQQQ

SOCS7

171

O14512
SRGEQQQQQQQQPPP

SOCS7

176

O14512
PQQQQQQKTSALSPN

TOB1

256

P50616
LQQLEQQPEPQQQPQ

ZNF853

91

P0CG23
QPQQDGQQQLSQLQQ

ZNF853

121

P0CG23
AQQVQVQQQSQVPPS

ZSWIM3

476

Q96MP5
NPPQQGEANQNDSVA

ZNF788P

11

Q6ZQV5
SSSQPIQHPQQQQGI

WNK1

731

Q9H4A3
IQHPQQQQGIQQTAP

WNK1

736

Q9H4A3
QQQGIQQTAPPQQTV

WNK1

741

Q9H4A3
QPSQSSHLPQNQQQQ

TET2

731

Q6N021
SQRIQTNNNPFQVPI

RELA

131

Q04206
QQQLRELCPGVNNQP

WBP1

21

Q96G27
NRPQQDQQGRPLSVQ

TNRC6A

1436

Q8NDV7
SPQQQQQQQVALGPG

KMT2D

3986

O14686