Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

SCYL2 PIK3R4 NEK1 FAM20C FLT1 PRKAA1 PRKAB1 PNCK PRKDC PFKFB3 ACVR1 PANK1 NRP1

1.32e-057098813GO:0016773
GeneOntologyMolecularFunctionlatrotoxin receptor activity

ADGRL1 ADGRL2

1.92e-052882GO:0016524
GeneOntologyMolecularFunctionkinase activity

SCYL2 PIK3R4 NEK1 FAM20C FLT1 PRKAA1 PRKAB1 PNCK PRKDC PFKFB3 ACVR1 PANK1 NRP1

2.89e-057648813GO:0016301
GeneOntologyMolecularFunctionprotein kinase activity

SCYL2 PIK3R4 NEK1 FAM20C FLT1 PRKAA1 PRKAB1 PNCK PRKDC ACVR1 NRP1

6.47e-056008811GO:0004672
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

SCYL2 PIK3R4 NEK1 FAM20C FLT1 PRKAA1 PRKAB1 PNCK PRKDC PFKFB3 ACVR1 PANK1 NRP1

2.28e-049388813GO:0016772
GeneOntologyMolecularFunctionvascular endothelial growth factor receptor activity

FLT1 NRP1

3.97e-047882GO:0005021
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

PIK3R4 NEK1 FAM20C PRKAA1 PRKAB1 PNCK PRKDC ACVR1

7.85e-04446888GO:0004674
GeneOntologyMolecularFunctionAMP-activated protein kinase activity

PRKAA1 PRKAB1

8.44e-0410882GO:0004679
GeneOntologyMolecularFunctionU3 snoRNA binding

DHX37 PRKDC

1.03e-0311882GO:0034511
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

TRAF6 IRF2BP1 CBLL2 RNF114 UBOX5 DDB2 OBI1 SMURF2

1.15e-03473888GO:0004842
GeneOntologyMolecularFunctionubiquitin-ubiquitin ligase activity

TRAF6 UBOX5

1.69e-0314882GO:0034450
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

PRAMEF33 PRAMEF10 PRAMEF17

1.84e-0355883GO:0042974
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

TRAF6 IRF2BP1 CBLL2 RNF114 UBOX5 DDB2 OBI1 SMURF2

1.89e-03512888GO:0019787
GeneOntologyMolecularFunctionacyltransferase activity

TRAF6 IRF2BP1 CBLL2 CLN5 RNF114 UBOX5 DDB2 OBI1 SMURF2 NAA16

2.15e-037758810GO:0016746
GeneOntologyMolecularFunctionaminoacyltransferase activity

TRAF6 IRF2BP1 CBLL2 RNF114 UBOX5 DDB2 OBI1 SMURF2

2.40e-03532888GO:0016755
MousePhenoabnormal erythrocyte osmotic lysis

NEK1 AMPD3 PRKAA1 PRKAB1

1.69e-0530734MP:0003657
MousePhenohemolysis

NEK1 AMPD3 PRKAA1 PRKAB1

2.82e-0534734MP:0010163
DomainLatrophilin

ADGRL1 ADGRL2 ADGRL3

1.01e-073883PF02354
DomainGPCR_2_latrophilin_rcpt_C

ADGRL1 ADGRL2 ADGRL3

1.01e-073883IPR003334
DomainGPCR_2_latrophilin

ADGRL1 ADGRL2 ADGRL3

1.00e-065883IPR003924
DomainLectin_gal-bd_dom

ADGRL1 ADGRL2 ADGRL3

1.00e-065883IPR000922
DomainGal_Lectin

ADGRL1 ADGRL2 ADGRL3

1.00e-065883PF02140
DomainSUEL_LECTIN

ADGRL1 ADGRL2 ADGRL3

1.00e-065883PS50228
DomainHEAT

SCYL2 PIK3R4 MROH1 PRKDC SPAG6

3.02e-0648885PF02985
DomainCUB

MASP1 NETO2 TLL2 CSMD3 NRP1

3.35e-0649885PF00431
DomainCUB

MASP1 NETO2 TLL2 CSMD3 NRP1

3.71e-0650885SM00042
Domain-

MASP1 NETO2 TLL2 CSMD3 NRP1

4.52e-06528852.60.120.290
DomainCUB

MASP1 NETO2 TLL2 CSMD3 NRP1

4.97e-0653885PS01180
DomainCUB_dom

MASP1 NETO2 TLL2 CSMD3 NRP1

7.15e-0657885IPR000859
DomainHEAT

SCYL2 PIK3R4 MROH1 PRKDC SPAG6

7.79e-0658885IPR000357
DomainGAIN_dom_N

ADGRL1 ADGRL2 ADGRL3

1.62e-0511883IPR032471
DomainGAIN

ADGRL1 ADGRL2 ADGRL3

1.62e-0511883PF16489
DomainHomeobox_antennapedia

HOXB4 HOXC4 HOXD4

2.16e-0512883IPR017995
DomainOLF

ADGRL1 ADGRL2 ADGRL3

2.79e-0513883PS51132
DomainOlfac-like_dom

ADGRL1 ADGRL2 ADGRL3

2.79e-0513883IPR003112
DomainOLF

ADGRL1 ADGRL2 ADGRL3

2.79e-0513883SM00284
DomainOLF

ADGRL1 ADGRL2 ADGRL3

2.79e-0513883PF02191
DomainSushi

MASP1 PAPPA C2 CSMD3

1.05e-0452884PF00084
DomainCCP

MASP1 PAPPA C2 CSMD3

1.22e-0454884SM00032
DomainHomeobox_Antennapedia_CS

HOXB4 HOXC4 HOXD4

1.26e-0421883IPR001827
DomainCalponin/LIMCH1

CNN1 CNN3

1.31e-044882IPR001997
DomainSUSHI

MASP1 PAPPA C2 CSMD3

1.40e-0456884PS50923
DomainSushi_SCR_CCP_dom

MASP1 PAPPA C2 CSMD3

1.50e-0457884IPR000436
DomainANTENNAPEDIA

HOXB4 HOXC4 HOXD4

1.90e-0424883PS00032
DomainHormR

ADGRL1 ADGRL2 ADGRL3

2.16e-0425883SM00008
DomainHRM

ADGRL1 ADGRL2 ADGRL3

3.04e-0428883PF02793
DomainCalponin_repeat

CNN1 CNN3

3.25e-046882IPR000557
DomainCalponin

CNN1 CNN3

3.25e-046882PF00402
DomainCALPONIN_1

CNN1 CNN3

3.25e-046882PS01052
DomainCALPONIN_2

CNN1 CNN3

3.25e-046882PS51122
DomainHEAT_REPEAT

SCYL2 PIK3R4 MROH1 PRKDC

3.33e-0470884PS50077
DomainGPS

ADGRL1 ADGRL2 ADGRL3

5.44e-0434883SM00303
DomainGPCR_2_secretin-like_CS

ADGRL1 ADGRL2 ADGRL3

5.44e-0434883IPR017983
DomainGPS

ADGRL1 ADGRL2 ADGRL3

5.93e-0435883PF01825
DomainGPS

ADGRL1 ADGRL2 ADGRL3

6.45e-0436883PS50221
DomainGPS

ADGRL1 ADGRL2 ADGRL3

6.99e-0437883IPR000203
DomainEGF_CA

MASP1 FAT1 HMCN2 TLL2

7.28e-0486884PF07645
DomainG_PROTEIN_RECEP_F2_1

ADGRL1 ADGRL2 ADGRL3

8.80e-0440883PS00649
DomainGPCR_2_extracellular_dom

ADGRL1 ADGRL2 ADGRL3

8.80e-0440883IPR001879
DomainG_PROTEIN_RECEP_F2_3

ADGRL1 ADGRL2 ADGRL3

8.80e-0440883PS50227
DomainEGF_Ca-bd_CS

MASP1 FAT1 HMCN2 TLL2

1.14e-0397884IPR018097
DomainEGF-like_dom

MASP1 FAT1 HMCN2 MUC17 TLL2 TECTA

1.15e-03249886IPR000742
DomainSM22_calponin

CNN1 CNN3

1.17e-0311882IPR003096
DomainEGF_CA

MASP1 FAT1 HMCN2 TLL2

1.23e-0399884PS01187
DomainEGF_1

LAMB4 MASP1 FAT1 HMCN2 MUC17 TLL2

1.30e-03255886PS00022
DomainEGF-like_CS

LAMB4 MASP1 FAT1 HMCN2 MUC17 TLL2

1.46e-03261886IPR013032
DomainEGF_2

LAMB4 MASP1 FAT1 HMCN2 MUC17 TLL2

1.58e-03265886PS01186
DomainEGF-type_Asp/Asn_hydroxyl_site

MASP1 FAT1 HMCN2 TLL2

1.59e-03106884IPR000152
DomainG_PROTEIN_RECEP_F2_2

ADGRL1 ADGRL2 ADGRL3

1.69e-0350883PS00650
Domain7tm_2

ADGRL1 ADGRL2 ADGRL3

1.69e-0350883PF00002
DomainEGF_CA

MASP1 FAT1 HMCN2 TLL2

2.65e-03122884SM00179
DomainEGF-like_Ca-bd_dom

MASP1 FAT1 HMCN2 TLL2

2.81e-03124884IPR001881
DomainGPCR_2_secretin-like

ADGRL1 ADGRL2 ADGRL3

2.85e-0360883IPR000832
DomainGPCR_2-like

ADGRL1 ADGRL2 ADGRL3

2.85e-0360883IPR017981
DomainHEAT_type_2

PIK3R4 MROH1

2.85e-0317882IPR021133
DomainG_PROTEIN_RECEP_F2_4

ADGRL1 ADGRL2 ADGRL3

2.99e-0361883PS50261
DomainPRAME_family

PRAMEF10 PRAMEF17

3.56e-0319882IPR026271
Domain-

SCYL2 PIK3R4 MROH1 PRKDC SPAG6

4.00e-032228851.25.10.10
DomainKinase-like_dom

SCYL2 PIK3R4 NEK1 FLT1 PRKAA1 PNCK PRKDC ACVR1

4.02e-03542888IPR011009
Pubmed

A family of heptahelical receptors with adhesion-like domains: a marriage between two super families.

ADGRL1 ADGRL2 ADGRL3

1.73e-08391310994649
Pubmed

The multiple actions of black widow spider toxins and their selective use in neurosecretion studies.

ADGRL1 ADGRL2 ADGRL3

1.73e-08391315066411
Pubmed

alpha-Latrotoxin and its receptors: neurexins and CIRL/latrophilins.

ADGRL1 ADGRL2 ADGRL3

1.73e-08391311520923
Pubmed

The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins.

ADGRL1 ADGRL2 ADGRL3

3.45e-07691310964907
Pubmed

Sequence and embryonic expression of the murine Hox-3.5 gene.

HOXB4 HOXC4 HOXD4

6.02e-0779131363091
Pubmed

Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations.

HOXB4 HOXC4 HOXD4

6.02e-0779138660891
Pubmed

The binding of Ku antigen to homeodomain proteins promotes their phosphorylation by DNA-dependent protein kinase.

HOXC4 HOXD4 PRKDC

9.61e-07891311279128
Pubmed

Hox genes regulate the onset of Tbx5 expression in the forelimb.

HOXB4 HOXC4 HOXD4

9.61e-07891322872086
Pubmed

Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.

ZAR1L PRAMEF33 PRAMEF10 PRAMEF17

1.14e-063091438786026
Pubmed

Region-specific gastrointestinal Hox code during murine embryonal gut development.

HOXB4 HOXC4 HOXD4

1.44e-06991311869294
Pubmed

Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code.

HOXB4 HOXC4 HOXD4

1.44e-06991310579975
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

ADGRL1 ADGRL2 ADGRL3

2.05e-061091338713721
Pubmed

Expression of class I homeobox genes in fetal and adult murine skin.

HOXB4 HOXC4 HOXD4

3.75e-06129138105001
Pubmed

Wnt-3a is required for somite specification along the anteroposterior axis of the mouse embryo and for regulation of cdx-1 expression.

HOXB4 HOXD4 WNT3A

3.75e-061291311335109
Pubmed

Regulation of erythrocyte survival by AMP-activated protein kinase.

PRKAA1 PRKAB1

6.77e-06291219050047
Pubmed

Enhanced technique to measure proteins in single segments of human skeletal muscle fibers: fiber-type dependence of AMPK-alpha1 and -beta1.

PRKAA1 PRKAB1

6.77e-06291221088205
Pubmed

Latrophilin receptors: novel bronchodilator targets in asthma.

ADGRL1 ADGRL3

6.77e-06291227325752
Pubmed

Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans.

ACVR1 PGR

6.77e-06291224244176
Pubmed

Molecular cloning and gene mapping of human basic and acidic calponins.

CNN1 CNN3

6.77e-0629128526917
Pubmed

Active Wnt proteins are secreted on exosomes.

WNT3A TSG101

6.77e-06291222983114
Pubmed

Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins.

ADGRL2 ADGRL3

6.77e-06291230792275
Pubmed

Differential Expression of VEGFA Isoforms Regulates Metastasis and Response to Anti-VEGFA Therapy in Sarcoma.

FLT1 PRKDC

6.77e-06291228377452
Pubmed

Activators of the energy sensing kinase AMPK inhibit random cell movement and chemotaxis in U937 cells.

PRKAA1 PRKAB1

6.77e-06291216405649
Pubmed

Latrophilin GPCR signaling mediates synapse formation.

ADGRL2 ADGRL3

6.77e-06291233646123
Pubmed

Lacteal junction zippering protects against diet-induced obesity.

FLT1 NRP1

6.77e-06291230093598
Pubmed

Mutations in paralogous Hox genes result in overlapping homeotic transformations of the axial skeleton: evidence for unique and redundant function.

HOXB4 HOXD4

6.77e-0629127750651
Pubmed

AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest.

PRKAA1 PFKFB3

6.77e-06291226322680
Pubmed

HOXC4 homeoprotein efficiently expands human hematopoietic stem cells and triggers similar molecular alterations as HOXB4.

HOXB4 HOXC4

6.77e-06291222298821
Pubmed

A distinct Hox code for the branchial region of the vertebrate head.

HOXB4 HOXC4 HOXD4

7.71e-06159131682814
Pubmed

New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.

HOXB4 HOXC4 HOXD4 WNT3A

9.21e-065091428188179
Pubmed

The mouse PcG gene eed is required for Hox gene repression and extraembryonic development.

HOXB4 HOXC4 HOXD4

1.91e-052091312370779
Pubmed

Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.

PRAMEF33 PRAMEF10 PRAMEF17

1.91e-052091326694250
Pubmed

Genetic variation within the hypothalamus-pituitary-ovarian axis in women with recurrent miscarriage.

PAPPA ACVR1 PGR

1.91e-052091320716560
Pubmed

VEGF-A165 induces human aortic smooth muscle cell migration by activating neuropilin-1-VEGFR1-PI3K axis.

FLT1 NRP1

2.03e-05391218284215
Pubmed

AMPK couples plasma renin to cellular metabolism by phosphorylation of ACC1.

PRKAA1 PRKAB1

2.03e-05391223785098
Pubmed

AMPKα1 Regulates Lung and Breast Cancer Progression by Regulating TLR4-Mediated TRAF6-BECN1 Signaling Axis.

TRAF6 PRKAA1

2.03e-05391233172060
Pubmed

AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells.

PRKAA1 PRKAB1

2.03e-05391219211918
Pubmed

Hoxd4 and Rarg interact synergistically in the specification of the cervical vertebrae.

HOXB4 HOXD4

2.03e-05391210559481
Pubmed

Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states.

PRKAA1 PRKAB1

2.03e-05391230478170
Pubmed

Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization.

PFKFB3 PGR

2.03e-05391224204309
Pubmed

AMPK is required for uterine receptivity and normal responses to steroid hormones.

PRKAA1 PGR

2.03e-05391232191914
Pubmed

Trafficking dynamics of VEGFR1, VEGFR2, and NRP1 in human endothelial cells.

FLT1 NRP1

2.03e-05391238324585
Pubmed

AMP-activated protein kinase positively regulates FGF-2-stimulated VEGF synthesis in osteoblasts.

PRKAA1 PRKAB1

2.03e-05391220708602
Pubmed

Use of FMF algorithm for prediction of preeclampsia in high risk pregnancies: a single center longitudinal study.

FLT1 PAPPA

2.03e-05391233979553
Pubmed

Endothelial H2S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.

PRKAA1 PRKAB1

2.03e-05391238266576
Pubmed

Galectin-1 induces vascular permeability through the neuropilin-1/vascular endothelial growth factor receptor-1 complex.

FLT1 NRP1

2.03e-05391224719187
Pubmed

Macrophage alpha1 AMP-activated protein kinase (alpha1AMPK) antagonizes fatty acid-induced inflammation through SIRT1.

PRKAA1 PRKAB1

2.03e-05391220421294
Pubmed

Red Pepper Seed Inhibits Differentiation of 3T3-L1 Cells during the Early Phase of Adipogenesis via the Activation of AMPK.

PRKAA1 PRKAB1

2.03e-05391229316805
Pubmed

Neuropilin-1 is required for endothelial cell adhesion to soluble vascular endothelial growth factor receptor 1.

FLT1 NRP1

2.03e-05391234252269
Pubmed

Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression.

PRKAA1 PRKAB1

2.03e-05391210760274
Pubmed

Functional analysis of rat acidic calponin.

CNN1 CNN3

2.03e-05391212033495
Pubmed

Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits.

PRKAA1 PRKAB1

2.03e-0539128663446
Pubmed

Predictive value of sFlt-1, PlGF, sFlt-1/PlGF ratio and PAPP-A for late-onset preeclampsia and IUGR between 32 and 37 weeks of pregnancy.

FLT1 PAPPA

2.03e-05391229674192
Pubmed

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism.

PRKAA1 PRKAB1

2.03e-05391221892142
Pubmed

Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function.

PRKAA1 PRKAB1

2.03e-05391227411013
Pubmed

The outcome of renal ischemia-reperfusion injury is unchanged in AMPK-β1 deficient mice.

PRKAA1 PRKAB1

2.03e-05391222253816
Pubmed

Iron regulates glucose homeostasis in liver and muscle via AMP-activated protein kinase in mice.

PRKAA1 PRKAB1

2.03e-05391223515442
Pubmed

Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly.

PRKAA1 PRKAB1

2.03e-05391230232152
Pubmed

A functional role for AMPK in female fertility and endometrial regeneration.

PRKAA1 PGR

2.03e-05391230328345
Pubmed

Inhibition of inducible nitric-oxide synthase by activators of AMP-activated protein kinase: a new mechanism of action of insulin-sensitizing drugs.

PRKAA1 PRKAB1

2.03e-05391214985344
Pubmed

Production and Crystallization of Full-Length Human AMP-Activated Protein Kinase (α1β1γ1).

PRKAA1 PRKAB1

2.03e-05391229480465
Pubmed

Role of AMP-activated protein kinase in autophagy and proteasome function.

PRKAA1 PRKAB1

2.03e-05391218328803
Pubmed

Tyrosine phosphorylation of calponins. Inhibition of the interaction with F-actin.

CNN1 CNN3

2.03e-05391215206927
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

PIK3R4 PDCD2 DHX37 XRN1 RNF114 HIF1AN

2.07e-0521291633853758
Pubmed

Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis.

HOXB4 HOXC4 HOXD4

2.23e-052191330254164
Pubmed

Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features.

HOXB4 HOXC4 HOXD4

2.23e-052191325381007
Pubmed

Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.

PRAMEF33 PRAMEF10 PRAMEF17

2.57e-052291331729367
Pubmed

Organization of human class I homeobox genes.

HOXB4 HOXC4 HOXD4

2.57e-05229132576652
Pubmed

Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects.

HOXB4 HOXC4 HOXD4

3.37e-05249139367423
Pubmed

MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.

PRAMEF33 PRAMEF10 PRAMEF17

3.82e-052591337451217
Pubmed

Estrogen Receptor β Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis.

PRKDC PGR

4.05e-05491226544941
Pubmed

VEGF receptors and neuropilins are expressed in the urothelial and neuronal cells in normal mouse urinary bladder and are upregulated in inflammation.

FLT1 NRP1

4.05e-05491218463314
Pubmed

Snake venom vascular endothelial growth factors (VEGFs) exhibit potent activity through their specific recognition of KDR (VEGF receptor 2).

FLT1 NRP1

4.05e-05491214600159
Pubmed

Proteolytic activities of two types of mannose-binding lectin-associated serine protease.

MASP1 C2

4.05e-05491210946292
Pubmed

Increased expression of VEGF-receptors (FLT-1, KDR, NRP-1) and thrombospondin-1 is associated with glomeruloid microvascular proliferation, an aggressive angiogenic phenotype, in malignant melanoma.

FLT1 NRP1

4.05e-05491215166498
Pubmed

Quantitative polymerase chain reaction analysis of cytotoxic cell proteinase gene transcripts in T cells. Pattern of expression is dependent on the nature of the stimulus.

GZMA CTLA4

4.05e-0549121544892
Pubmed

Controlling skeletal muscle CPT-I malonyl-CoA sensitivity: the importance of AMPK-independent regulation of intermediate filaments during exercise.

PRKAA1 PRKAB1

4.05e-05491227941154
Pubmed

Neuropilin-1 regulates a new VEGF-induced gene, Phactr-1, which controls tubulogenesis and modulates lamellipodial dynamics in human endothelial cells.

FLT1 NRP1

4.05e-05491221939755
Pubmed

Activation of 5'-AMP-activated kinase with diabetes drug metformin induces casein kinase Iepsilon (CKIepsilon)-dependent degradation of clock protein mPer2.

PRKAA1 PRKAB1

4.05e-05491217525164
Pubmed

Epidermal autonomous VEGFA/Flt1/Nrp1 functions mediate psoriasis-like disease.

FLT1 NRP1

4.05e-05491231934626
Pubmed

Functional modulation of AMP-activated protein kinase by cereblon.

PRKAA1 PRKAB1

4.05e-05491221232561
Pubmed

Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum.

ADGRL2 ADGRL3

4.05e-05491232202499
Pubmed

Regulation of AMPK Activity by CRBN Is Independent of the Thalidomide-CRL4CRBN Protein Degradation Axis.

PRKAA1 PRKAB1

4.05e-05491234073624
Pubmed

Differential binding of vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1.

FLT1 NRP1

4.05e-05491210409677
Pubmed

Mouse homeo-genes within a subfamily, Hox-1.4, -2.6 and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation.

HOXB4 HOXD4

4.05e-0549122576400
Pubmed

The interaction of neuropilin-1 with vascular endothelial growth factor and its receptor flt-1.

FLT1 NRP1

4.05e-05491210842181
Pubmed

AMP kinase promotes glioblastoma bioenergetics and tumour growth.

PRKAA1 PRKAB1

4.05e-05491229915361
Pubmed

Somatic mutation of vascular endothelial growth factor receptors in juvenile hemangioma.

FLT1 NRP1

4.05e-05491211807987
Pubmed

Compound mutants for the paralogous hoxa-4, hoxb-4, and hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed.

HOXB4 HOXD4

4.05e-0549127628700
Pubmed

Positive cross-regulation and enhancer sharing: two mechanisms for specifying overlapping Hox expression patterns.

HOXB4 HOXD4

4.05e-0549129106661
Pubmed

Suppression of 5'-nucleotidase enzymes promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscle.

PRKAA1 PRKAB1

4.05e-05491221873433
Pubmed

Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva.

PRKDC ACVR1

4.05e-05491229396429
Pubmed

Synergistic Binding of Vascular Endothelial Growth Factor-A and Its Receptors to Heparin Selectively Modulates Complex Affinity.

FLT1 NRP1

4.05e-05491225979342
Pubmed

Dendritic cell expression of the signaling molecule TRAF6 is critical for gut microbiota-dependent immune tolerance.

TRAF6 PRKDC

4.05e-05491223791643
Pubmed

AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance.

PRKAA1 PRKAB1

4.05e-05491218390901
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

MYCN HOXB4 HOXC4 HOXD4 ACVR1 NRP1

5.31e-0525191629031500
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF33 PRAMEF10 PRAMEF17

5.41e-052891325089626
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRL1 ADGRL2 ADGRL3

6.03e-052991315203201
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

JPH1 SMCHD1 XRN1 PRKDC PFKFB3 OSMR TECTA CSMD3

6.18e-0551391825798074
Pubmed

Genome-wide association study of maternal and inherited loci for conotruncal heart defects.

SMCHD1 PAPPA

6.74e-05591224800985
Cytoband1p36.21

PRAMEF33 PRAMEF10 PRAMEF17

2.74e-04639131p36.21
Cytoband9p13.2

POLR1E ZCCHC7

5.82e-04189129p13.2
GeneFamilyAdhesion G protein-coupled receptors, subfamily L

ADGRL1 ADGRL2 ADGRL3

1.25e-074583918
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

MASP1 PAPPA C2 CSMD3

3.32e-05575841179
GeneFamilyHOXL subclass homeoboxes

HOXB4 HOXC4 HOXD4

6.19e-0452583518
GeneFamilyPRAME family

PRAMEF10 PRAMEF17

2.67e-0324582686
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|390C / Donor, Lineage, Cell class and subclass (all cells)

FLT1 TRPC1 ADGRL2 CNN3 ADGRL3 NRP1

1.46e-061729166f302ed795767a9636081dc64373f8f039ea16d2
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|390C / Donor, Lineage, Cell class and subclass (all cells)

FLT1 TRPC1 ADGRL2 CNN3 ADGRL3 NRP1

1.46e-06172916fd8097299fc05390b30afaa9e6c80b1f607c27aa
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MASP1 HOXC4 ASIC1 PAPPA C2 TMEM151A

2.02e-061829169966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCellControl-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

FLT1 FAT1 NETO2 ADGRL2 ADGRL3 NRP1

2.44e-0618891688b3415e33db81726dd29c1f50c886e057af50a0
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MASP1 CHODL PNCK CPED1 PI15 CNN1

2.44e-06188916879de94924de978478696fc7838e05a4d795b905
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

FLT1 FAT1 KIAA1549 ADGRL2 SMURF2 NRP1

2.59e-061909167f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HMCN2 PAPPA OSMR PI15 CNN1 ADGRL3

3.29e-06198916dc6d9032c5029527e184ac13b887c0c1f22ef1c0
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JPH1 HOXB4 TLL2 DDB2 ADGRL3

8.23e-0613491564979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

JPH1 HOXB4 SCAMP5 DDB2 ADGRL3

1.09e-051429155690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN2 CHODL WNT3A PNCK CNN1

1.94e-051609158624f101828efd32cdd38a65df8d94d690720a63
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN2 CHODL WNT3A PNCK CNN1

1.94e-051609159de3dd6b9d4b51314d60b3b01f4132bcfa2dfc18
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Thalamus / BrainAtlas - Mouse McCarroll V32

MASP1 MUC17 CTLA4 TECTA

1.99e-05789145b45aacaff2a2b98c4ef8e7ac51ad482a69a1d8b
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)|Thalamus / BrainAtlas - Mouse McCarroll V32

MASP1 MUC17 CTLA4 TECTA

1.99e-0578914afed2f358c8a33889931bc5ad8cb24f92323e6f8
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPC1 PAPPA ADGRL2 CSMD3 ADGRL3

2.90e-05174915f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT1 PAPPA CPED1 PI15 ADGRL3

2.90e-05174915015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellCOPD-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

MASP1 FLT1 OSMR ADGRL2 CNN3

3.32e-051799159968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MASP1 HOXC4 ASIC1 C2 TMEM151A

3.32e-05179915adf8b025032a03dbb58871a92025cd7efbeb22ff
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

MASP1 ASIC1 PAPPA CNN3 LRRC17

3.41e-05180915137fc14859c89e1ecd98bee388bb58c04b835847
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JPH1 HOXC4 PAPPA PI15 CNN1

3.41e-05180915d67d3196e6cc3dcd31023a4dc69310226181d583
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JPH1 HOXC4 PAPPA PI15 CNN1

3.41e-05180915573308d43425d9fba20787abdb7f8efefc48efb5
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

MASP1 ASIC1 PAPPA CNN3 LRRC17

3.41e-05180915cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHODL PNCK CPED1 PI15 CNN1

3.69e-0518391561a73de857f4ae02dcba3af348f436f602b28ff2
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HOXC4 ASIC1 PAPPA C2 TMEM151A

3.79e-05184915607b55022de21ddb6a2d75e085df76df7abf6624
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MASP1 HMCN2 CHODL PI15 CNN1

3.79e-05184915590fb32bb1f348ea5fa2aece30ebe1e212512991
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

JPH1 FAT1 CHODL ASIC1 PAPPA

3.89e-051859150094f9baddb20214d2a2c166f1637d1a9cf1169a
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYCN HOXC4 SCAMP5 TECTA CSMD3

3.99e-05186915bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHODL PNCK CPED1 PI15 CNN1

4.31e-05189915ab7ece0a517499b70b7754720d3e434765363af6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 CPED1 PI15 CNN1 ADGRL3

4.41e-051909152e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 CPED1 PI15 CNN1 ADGRL3

4.41e-051909150028f886c789ba238c031eae5d96acaed4af8c25
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT1 CPED1 PI15 CNN1 ADGRL3

4.41e-05190915d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

FAT1 CPED1 PI15 CNN1 ADGRL3

4.53e-05191915fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PAPPA OSMR CPED1 PI15 NRP1

4.99e-051959153d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AMPD3 MASP1 KIAA1549 ADGRL2 NRP1

4.99e-051959157e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 C2 OSMR CPED1 PI15

5.12e-051969156bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 C2 OSMR CPED1 PI15

5.12e-05196915c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 CPED1 CNN1 ADGRL3 PGR

5.12e-051969151522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 CPED1 CNN1 ADGRL3 PGR

5.12e-051969151c8294014713684b50885e638668f2ce75f357f0
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYCN MASP1 ASIC1 CNN3 LRRC17

5.12e-0519691545d1c0a962c4221c17393ee5566961d1deebf442
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HMCN2 OSMR PI15 ADGRL3 CCDC144A

5.24e-05197915cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCellCOPD-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

FLT1 KIAA1549 OSMR ADGRL2 SMURF2

5.24e-0519791530dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HMCN2 CPED1 CNN1 ADGRL3 PGR

5.24e-05197915bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLT1 KIAA1549 OSMR ADGRL2 CNN3

5.24e-051979156ac8d3e3f573e3848ab33e4df66dfaf8f948ea6c
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLT1 KIAA1549 OSMR ADGRL2 CNN3

5.24e-05197915e3be7758a92f12e0a423394822957e1b7f995110
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT1 OSMR ADGRL2 CNN3 NRP1

5.50e-0519991507bda4ac8ffdce1a865ebc99e46c2a27925ff7a8
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TECTA CPED1 CNN1 ADGRL3 PGR

5.50e-051999158ff0fdcbe9661b013913731ec8b53d84836ca865
ToppCellILEUM-non-inflamed-(8)_Smooth_muscle_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LAMB4 FAT1 CPED1 CNN1 ADGRL3

5.50e-051999153368c0a90a47c4dcdfe70be3192550df0744e508
ToppCelldistal-3-Endothelial-Capillary_Aerocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLT1 NETO2 ADGRL2 CNN3 NRP1

5.63e-05200915e12598a097dd9c4cbf9bb85bfa3057722ef73ad5
ToppCellmedial-Endothelial-Capillary|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLT1 KIAA1549 OSMR ADGRL2 CNN3

5.63e-05200915fd4dcdc67db2a5dbdd54bd2ae975c66df904d4d8
ToppCellLPS_IL1RA|World / Treatment groups by lineage, cell group, cell type

FLT1 OSMR ADGRL2 SMURF2 ADGRL3

5.63e-05200915a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FAM20C FAT1 PAPPA OSMR NRP1

5.63e-05200915ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

FLT1 SMCHD1 XRN1 ADGRL2 CNN3

5.63e-05200915edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HMCN2 CPED1 PI15 CNN1 ADGRL3

5.63e-05200915a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellmedial-2-Endothelial-Capillary|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLT1 KIAA1549 OSMR ADGRL2 CNN3

5.63e-05200915e4f390dfd4dd25600f0f7a17c5523283a5966e92
ToppCellmedial-Endothelial-Capillary-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLT1 KIAA1549 OSMR ADGRL2 CNN3

5.63e-052009154291b5453e98e20ec8150a96ccc865a5964bc645
ToppCelldistal-Endothelial-Capillary_Aerocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NETO2 ADGRL2 CNN3 ADGRL3 NRP1

5.63e-05200915d36236c7703b759309c8347f44900fc4bed377f0
ToppCelldistal-Endothelial-Capillary-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLT1 KIAA1549 OSMR ADGRL2 CNN3

5.63e-05200915ab96d3d801373459a2503ccfb665dc3f43bfb5a1
ToppCellLPS-IL1RA-Endothelial-Mes-Like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HOXC4 TLL2 CNN1 PGR

9.75e-051179145a23770806b4612bed4ae6fd716abdec7f7f56c6
ToppCellVE-CD4-CD8_1|VE / Condition, Cell_class and T cell subcluster

TMEM272 GZMA OSMR SPAG6

1.18e-04123914bc0f509716bb71d6e3fa343f4920ecb80eb62794
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Rasd1_(Presubiculum,_Col5a2+)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HOXB4 MUC17 TECTA

1.84e-0454913e40294b708b06f7eee1c099fc67f53a3bb76e306
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2-Rasd1_(Presubiculum,_Col5a2+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HOXB4 MUC17 TECTA

1.84e-0454913a1b3f38a90ca975a3e9c4dadfe3cd4e701a6cb1e
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRC14B FLT1 CACNA2D4 ADGRL3

2.17e-041449141b9e95e4f6e40042d3cf2f94c067f3a6b19428ea
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

POLR1E GZMA CTLA4 OBI1

2.47e-041499141328ce0104d40215ee68abfdbf74eb47b87a7b5b
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|368C / Donor, Lineage, Cell class and subclass (all cells)

HOXC4 GZMA CTLA4 UBOX5

2.53e-04150914c843bcf98c5fad2ca4339602f721f3fb782ae353
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCR10 ASIC1 TRPC1 CSMD3

2.66e-04152914655d47efe0608d729801f1f01668e84c1bc0675f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT1 TRAF6 ASIC1 CSMD3

2.73e-041539149c6fce56300ba5053efda59a438d63a808c497c0
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ELAPOR2 ASIC1 C2 TMEM151A

2.94e-04156914574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ELAPOR2 ASIC1 C2 TMEM151A

2.94e-04156914605d95a900e1443d3f6aae163ef2e893d3293203
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HOXB4 FAT1 CPED1 CNN3

3.01e-04157914b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 CPED1 CNN1 ADGRL3

3.16e-04159914cfb4a8c8aac34b1a857956d98382d487abcf5444
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 CPED1 CNN1 ADGRL3

3.16e-04159914a75ab494959575143cefdaec99e7aee3f318d559
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

CCR10 CPED1 CNN1 ADGRL3

3.31e-0416191464891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GZMA XRN1 PAPPA CTLA4

3.39e-0416291419395bdb282b4a2d88cd33191af12c24a88c3d16
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMB4 FLT1 ADGRL2 ADGRL3

3.47e-04163914977a970b1296234c22178420294cea73506ee02f
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-erythroid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HOXD4 C2 PI15 NRP1

3.47e-04163914240d9f0ea45e8b2c7173e7674fd740555810f9e7
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMB4 FLT1 ADGRL2 ADGRL3

3.47e-04163914ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCellNS-critical-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HOXB4 SCAMP5 CPED1 NRP1

3.64e-0416591417d5c4a111d9b5400780bc5e7b93ce2f5d69ceb7
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

LRRC14B MASP1 ACRBP TSG101

3.72e-04166914063d68f2ffb40770cb4601fa1cb6426ae26f7a37
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

LRRC14B MASP1 ACRBP TSG101

3.72e-04166914417cfb207da08fa1a0fd5f2a13c8786628667a8e
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

LRRC14B MASP1 ACRBP TSG101

3.72e-04166914f28d07715e6b00ca2a0df39273c5f569744be5a8
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HOXC4 ASIC1 C2 TMEM151A

3.81e-041679147abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HOXC4 ASIC1 C2 TMEM151A

3.81e-04167914d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JPH1 MASP1 FAT1 CNN1

3.81e-0416791491b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a6.Nell1_(Neuron.Slc17a6.Nell1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZAR1L GZMA TECTA

3.81e-046991311e6747ed4a45acee210c48ba670bfe0375fb19b
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a6.Nell1_(Neuron.Slc17a6.Nell1)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZAR1L GZMA TECTA

3.81e-046991396564b46008a6e5220b6596cbbe0a24e9b5955ee
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCAMP5 KIAA1549 C2 CPED1

3.89e-04168914d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLT1 ADGRL2 CNN3 NRP1

3.98e-0416991441ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB4 PAPPA ADGRL2 ADGRL3

3.98e-04169914c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHODL C2 OSMR CPED1

3.98e-04169914031465190cd3623a25ef2b868daab8d932c8ff08
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLT1 ADGRL2 CNN3 NRP1

3.98e-0416991442782c61592742190ab0cba8a94f8bdf9c278f90
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TRPC1 ADGRL2 ADGRL3 NRP1

4.07e-04170914a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TRPC1 ADGRL2 ADGRL3 NRP1

4.07e-04170914b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 CCR10 NETO2 STXBP5

4.16e-04171914913bae728b5e653771a27c79a309eb023699f1d0
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 CCR10 NETO2 STXBP5

4.16e-04171914f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

MASP1 ADGRL2 PI15 CNN1

4.16e-04171914080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAPPA CPED1 PI15 CNN1

4.16e-041719144ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCR10 POLR1E TRPC1 CTLA4

4.25e-0417291430f4979abf0218618a56afb06aa6afc23ad838ec
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

PNCK PI15 CNN1 ADGRL3

4.35e-04173914a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CPED1 PI15 CNN1 ADGRL3

4.35e-04173914cb6389536195443633adb06e5f1b7483530773d1
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB4 FLT1 PFKFB3 NRP1

4.35e-04173914fbc8ed566ea36c39c258dd6b3823c82f5d6eb17f
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB4 FLT1 CACNA2D4 NRP1

4.44e-04174914fa6eb451555766398996bbe8f555a3f4c0f3c108
Diseaseleukemia (implicated_via_orthology)

HOXB4 HOXC4 HOXD4

2.32e-0519873DOID:1240 (implicated_via_orthology)
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

ADGRL1 ADGRL2 ADGRL3

7.69e-0528873DOID:1094 (implicated_via_orthology)
DiseaseAdenoid Cystic Carcinoma

MYCN FAT1 NETO2 PRKDC

2.23e-04100874C0010606
Diseaseplacenta growth factor measurement

FLT1 NRP1

4.65e-0411872EFO_0010626
Diseasepreeclampsia, parental genotype effect measurement

FLT1 WNT3A

1.00e-0316872EFO_0000668, EFO_0005939
DiseaseCerebral Astrocytoma

KIAA1549 ACVR1

2.47e-0325872C0750935
DiseaseIntracranial Astrocytoma

KIAA1549 ACVR1

2.47e-0325872C0750936
DiseasePilocytic Astrocytoma

KIAA1549 ACVR1

2.47e-0325872C0334583
DiseaseAstrocytoma

KIAA1549 ACVR1

2.47e-0325872C0004114
DiseaseJuvenile Pilocytic Astrocytoma

KIAA1549 ACVR1

2.47e-0325872C0280783
DiseaseDiffuse Astrocytoma

KIAA1549 ACVR1

2.47e-0325872C0280785
DiseaseGrade I Astrocytoma

KIAA1549 ACVR1

2.47e-0325872C1704230
DiseaseSubependymal Giant Cell Astrocytoma

KIAA1549 ACVR1

2.47e-0325872C0205768
DiseaseMixed oligoastrocytoma

KIAA1549 ACVR1

2.47e-0325872C0547065
DiseaseChildhood Cerebral Astrocytoma

KIAA1549 ACVR1

2.47e-0325872C0338070
DiseaseGemistocytic astrocytoma

KIAA1549 ACVR1

2.67e-0326872C0334581
DiseaseProtoplasmic astrocytoma

KIAA1549 ACVR1

2.67e-0326872C0334580
DiseaseFibrillary Astrocytoma

KIAA1549 ACVR1

2.67e-0326872C0334582
DiseaseAnaplastic astrocytoma

KIAA1549 ACVR1

2.88e-0327872C0334579

Protein segments in the cluster

PeptideGeneStartEntry
IPDLDSPFLCLYYPQ

PRAMEF33

256

A0A0G2JMD5
VPEKPPAGECVTFYF

BBS7

531

Q8IWZ6
AYSAEPLPELCYKAD

CCR10

21

P46092
EYNLEPCEDPGIPQY

CSMD3

1176

Q7Z407
NPDFHPKIKDYYCEV

CPED1

586

A4D0V7
FPDPCPGTYKYLEVQ

ADGRL1

111

O94910
DFPTKICDTDYIQYP

ACRBP

471

Q8NEB7
LVKKEFPYPCYDPAT

GZMA

96

P12544
DYKPPFYDVVPNDPS

ACVR1

426

Q04771
FPDPCPGTYKYLEVQ

ADGRL3

106

Q9HAR2
VFPDPCPGTYKYLEV

ADGRL2

111

O95490
YEKYKIPACPEEEPL

CCDC144CP

256

Q8IYA2
AKKPTPPDYYPECQS

CBLL2

251

Q8N7E2
EDPYCLDDAPPNLDY

AMPD3

206

Q01432
IKETCYPDIPDPYKS

OSMR

766

Q99650
AKPPYVCDITVPDAY

KIAA1549

941

Q9HCM3
DINDCPPVFAKPLYE

FAT1

1871

Q14517
VPDLDCPFLCLYYPQ

PRAMEF17

256

Q5VTA0
TPYYLSPEICENKPY

NEK1

166

Q96PY6
CILFPPDQFECLYPY

HIF1AN

216

Q9NWT6
SYVNKEFAVCPSYPP

MTMR9

146

Q96QG7
AYLYCDTNAIPPPDL

HMCN2

2776

Q8NDA2
YYEECPKDKLPAYPE

LRRC17

396

Q8N6Y2
EPICRQPYSYDFPED

C2

201

P06681
ELSPDFYQPGPDYVK

JPH1

411

Q9HDC5
EIEEAYCYTSPGPPK

HMGXB3

16

Q12766
PRKNDFYSYEPPSEN

PDCD2

101

Q16342
CDFFSPYENGEKEPP

NAA16

356

Q6N069
ISCYEASYQPLDPDK

PFKFB3

191

Q16875
VPYKDEELYDLPAPC

OBI1

376

Q5W0B1
PKDCYPEGAAYPQDE

LRRC14B

426

A6NHZ5
PEPQGCYLELEFLYP

PAPPA

776

Q13219
YPDPNFKSCTPYELR

DDB2

356

Q92466
PCYDEAPQEKNFLYK

MROH1

636

Q8NDA8
RPLPPCQEKDYHFEY

ELAPOR2

56

A8MWY0
NYVDPKFPPCEEYSQ

HOXB4

11

P17483
KFPPCEEYSQSDYLP

HOXB4

16

P17483
KYVDPKFPPCEEYLQ

HOXD4

11

P09016
LCGYPPFYDESDPEL

PNCK

206

Q6P2M8
PGFPEKYPNSLECTY

NRP1

161

O14786
CAYPPDAEPKDDAYP

PGR

361

P06401
VDPDYCEEVKQTPPY

FAM20C

421

Q8IXL6
DPLQPCDTEYPVFVY

CACNA2D4

1006

Q7Z3S7
CCFPSYVYPDPTQEE

CENPJ

216

Q9HC77
NYIDPKFPPCEEYSQ

HOXC4

11

P09017
KFPPCEEYSQNSYIP

HOXC4

16

P09017
YEKYKIPACPEEEPL

CCDC144B

306

Q3MJ40
DFPNPYPKSSECLYT

MASP1

201

P48740
ICDSRFPYDPYDQPN

LAMB4

71

A4D0S4
PTEPECEKQFQPYFI

CTLA4

206

P16410
YEKYKIPACPEEEPL

CCDC144A

306

A2RUR9
CPTPDFEDLPERYQK

FAM161A

426

Q3B820
YCQFDKPLEEPAPTY

DHX37

1011

Q8IY37
PLKPCFYQDFEADIP

SCAMP5

16

Q8TAC9
PGYEFELKLFTEYPC

IRF2BP1

266

Q8IU81
GKPECYYFENPTNPE

PANK1

381

Q8TE04
EYRDQKPYCISPCEP

MUC17

4331

Q685J3
DSLYLPPCYDDAAKP

POLR1E

196

Q9GZS1
PPCYDDAAKPEDVYK

POLR1E

201

Q9GZS1
SPYFKKEPVYQLPCG

UBOX5

491

O94941
DQPYEPVSPYSCKEA

EPRS1

681

P07814
CTYLPALEPFLYDAP

SPAG6

411

O75602
PFLYDRETYPDDPCF

SMCHD1

431

A6NHR9
CLPNPEYLAPEYILS

SCYL2

226

Q6P3W7
YPPNKECIYILEAAP

NETO2

66

Q8NC67
PLESPPCYEDALYFP

TMEM151A

436

Q8N4L1
CETPYPNDFQEPYAV

STXBP5

351

Q5T5C0
QDLPKYLFPEDPSYS

PRKAA1

281

Q13131
PYHQEPYVCKPEERF

PRKAB1

186

Q9Y478
PGDAPYCTPEQYKEC

ASIC1

331

P78348
DFRPKPDPYCQAKYT

CLN5

61

O75503
YICKYEPEINPTAPV

CHODL

176

Q9H9P2
QVYDPKYCLTPEYPE

CNN1

266

P51911
KYCLTPEYPELGEPA

CNN1

271

P51911
QVYDPKYCAAPTEPV

CNN3

266

Q15417
LLDTYPYNPPICFVK

TSG101

76

Q99816
KPTYLPEDNPADFNY

PIK3R4

171

Q99570
CFNRIDIPPYESYEK

SMURF2

716

Q9HAU4
FQPCYGLLDPLPFYE

TECTA

1701

O75443
YFDDKCTLPPPFNII

TRPC1

671

P48995
EKPYEYEQCSTAFPA

ZNF441

221

Q8N8Z8
DEPIPQKPQSAFYYC

RALGAPA1

1751

Q6GYQ0
NPDLEFDSLQPCFYP

MYCN

16

P04198
PNRYTFPCPYCPEKN

RNF114

136

Q9Y508
YDVEFDPPLESKYEC

TRAF6

56

Q9Y4K3
NEDSPIIEYYPPDFK

XRN1

536

Q8IZH2
QSPNYPDDYRPSKEC

TLL2

476

Q9Y6L7
IPDLDSPFLCLYYPQ

PRAMEF10

256

O60809
CTPAAPPYYCDIKQE

ZBTB47

131

Q9UFB7
PPYYCDIKQEADTPG

ZBTB47

136

Q9UFB7
EYTPKRQEICPASYP

SAXO2

356

Q658L1
AAYLSDPRAPPCEYK

PRKDC

3826

P78527
LVYYEASPNFCEPNP

WNT3A

271

P56704
PSPVSPFICYYDDKY

ZCCHC7

371

Q8N3Z6
VKDYAFPYPQDCNPR

PI15

146

O43692
YEKAVSSFPDPALYP

FLT1

431

P17948
VPANAPDYCIDPYKR

ZAR1L

51

A6NP61
PPFQQPQDYCDKTLY

TMEM272

136

A0A1B0GTI8