Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionthiamine pyrophosphate binding

OGDH TKT OGDHL

9.42e-0681123GO:0030976
GeneOntologyMolecularFunctionantiporter activity

SLC25A21 SLC26A3 SLC35D2 SLC26A4 SLC7A6 SLC7A9

1.28e-041381126GO:0015297
GeneOntologyMolecularFunctionbasic amino acid transmembrane transporter activity

SLC7A6 SLC7A9 SLC15A4

1.83e-04201123GO:0015174
GeneOntologyMolecularFunctionoxoglutarate dehydrogenase (succinyl-transferring) activity

OGDH OGDHL

1.86e-0441122GO:0004591
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

SRCAP GATAD2B PBRM1 BAZ1A DPF3

1.67e-04961125GO:0070603
GeneOntologyCellularComponentPR-DUB complex

ASXL1 ASXL2

1.70e-0441122GO:0035517
GeneOntologyCellularComponentmyosin filament

MYO18A MYBPC1 MYBPC3

3.16e-04251123GO:0032982
DomainTransketolase-like_Pyr-bd

OGDH TKT OGDHL

1.15e-0581123IPR005475
DomainTransket_pyr

OGDH TKT OGDHL

1.15e-0581123SM00861
DomainTransket_pyr

OGDH TKT OGDHL

1.15e-0581123PF02779
Domain2-oxogl_dehyd_N

OGDH OGDHL

3.56e-0521122IPR032106
Domain2-oxogl_dehyd_N

OGDH OGDHL

3.56e-0521122PF16078
DomainTHDP-binding

OGDH TKT OGDHL

5.75e-05131123IPR029061
Domain-

OGDH TKT OGDHL

5.75e-051311233.40.50.970
DomainHARE-HTH

ASXL1 ASXL2

1.07e-0431122PF05066
DomainASXH

ASXL1 ASXL2

1.07e-0431122PF13919
DomainPHD_3

ASXL1 ASXL2

1.07e-0431122PF13922
DomainASX-like_PHD

ASXL1 ASXL2

1.07e-0431122IPR026905
Domain2oxoglutarate_DH_E1

OGDH OGDHL

1.07e-0431122IPR011603
DomainASXH

ASXL1 ASXL2

1.07e-0431122IPR028020
DomainKGD_C

OGDH OGDHL

1.07e-0431122IPR031717
DomainASX/ASX-like

ASXL1 ASXL2

1.07e-0431122IPR024811
DomainOxoGdeHyase_C

OGDH OGDHL

1.07e-0431122PF16870
DomainHB1/Asxl_HTH

ASXL1 ASXL2

1.07e-0431122IPR007759
DomainFN3

IL13RA1 IL31RA FSD1L IGSF9 USH2A MYBPC1 MYBPC3

1.98e-041991127PS50853
DomainFN3_dom

IL13RA1 IL31RA FSD1L IGSF9 USH2A MYBPC1 MYBPC3

2.67e-042091127IPR003961
DomainZF_PHD_2

ASXL1 BAZ1A DPF3 KDM2A ASXL2

2.67e-04951125PS50016
DomainZF_PHD_1

ASXL1 BAZ1A DPF3 KDM2A ASXL2

2.81e-04961125PS01359
Domainfn3

IL31RA FSD1L IGSF9 USH2A MYBPC1 MYBPC3

4.35e-041621126PF00041
DomainE1_dh

OGDH OGDHL

5.26e-0461122PF00676
DomainDH_E1

OGDH OGDHL

5.26e-0461122IPR001017
DomainS04_transporter_CS

SLC26A3 SLC26A4

7.34e-0471122IPR018045
DomainFN3

IL31RA FSD1L IGSF9 USH2A MYBPC1 MYBPC3

8.74e-041851126SM00060
DomainSLC26A

SLC26A3 SLC26A4

1.55e-03101122PS01130
DomainSTAS

SLC26A3 SLC26A4

1.89e-03111122PS50801
DomainZF_CXXC

KDM2A DNMT1

1.89e-03111122PS51058
DomainIL6Ra-bind

IL13RA1 IL31RA

1.89e-03111122PF09240
DomainBAH

PBRM1 DNMT1

1.89e-03111122PS51038
DomainSTAS

SLC26A3 SLC26A4

1.89e-03111122PF01740
DomainSLC26A/SulP_fam

SLC26A3 SLC26A4

1.89e-03111122IPR001902
DomainBAH_dom

PBRM1 DNMT1

1.89e-03111122IPR001025
DomainBAH

PBRM1 DNMT1

1.89e-03111122SM00439
DomainSTAS_dom

SLC26A3 SLC26A4

1.89e-03111122IPR002645
DomainZnf_CXXC

KDM2A DNMT1

1.89e-03111122IPR002857
DomainSLC26A/SulP_dom

SLC26A3 SLC26A4

1.89e-03111122IPR011547
DomainBAH

PBRM1 DNMT1

1.89e-03111122PF01426
Domainzf-CXXC

KDM2A DNMT1

1.89e-03111122PF02008
Domain-

SLC26A3 SLC26A4

1.89e-031111223.30.750.24
DomainSulfate_transp

SLC26A3 SLC26A4

1.89e-03111122PF00916
DomainTypeI_recpt_CBD

IL13RA1 IL31RA

1.89e-03111122IPR015321
DomainZnf_PHD

ASXL1 BAZ1A DPF3 KDM2A

2.19e-03911124IPR001965
DomainPX

SNX30 SH3PXD2A SNX12

2.32e-03441123SM00312
DomainAA_permease_2

SLC7A6 SLC7A9

2.66e-03131122PF13520
DomainAA/rel_permease1

SLC7A6 SLC7A9

2.66e-03131122IPR002293
PathwayREACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS

XDH PPL BTN3A3

3.73e-0512803M27738
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ELOA DHX37 SYNPO SRCAP CHAMP1 GATAD2B PBRM1 NOP14 BAZ1A ZBTB21 KDM2A DNMT1

7.99e-076081141236089195
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TTLL3 CARMIL1 RNF213 SYNPO IDE OGDH NRP1 CSDE1 SNX30 SH3PXD2A CDK5RAP1 IGSF9 KDM2A GREB1 HPS5 CRAMP1 TRAPPC9

7.26e-0614891141728611215
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

EMC3 PLGRKT MRPL30 RNF213 IDE LBR OGDH POLR3A STAU1 SCYL2 PIKFYVE NOP14 MRPL16 PI4KA CDK5RAP1 OGDHL TRIM13

7.71e-0614961141732877691
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

ELOA DHX37 MYO18A OGDH STAU1 CSDE1 PBRM1 NOP14 BAZ1A OGDHL UTP20 DNMT1

7.75e-067591141235915203
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SETD1B DHX37 LBR SRCAP POLR3A STAU1 CSDE1 NOP14 BAZ1A TKT PI4KA UTP20 KDM2A RIC8A DDX60L DNMT1

8.98e-0613531141629467282
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ELOA RPS6KA5 CARMIL1 MYO18A CHAMP1 GATAD2B PPL MED24 TKT ZBTB21 UTP20 DNMT1

9.43e-067741141215302935
Pubmed

A novel missense mutation in the myosin binding protein-C gene is responsible for hypertrophic cardiomyopathy with left ventricular dysfunction and dilation in elderly patients.

MYBPC1 MYBPC3

1.07e-052114212628722
Pubmed

ASXL1/2 mutations and myeloid malignancies.

ASXL1 ASXL2

1.07e-052114236068610
Pubmed

ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.

ASXL1 ASXL2

1.07e-052114228516957
Pubmed

Silencing of endogenous envelope genes in human choriocarcinoma cells shows that envPb1 is involved in heterotypic cell fusions.

ERVW-1 PBRM1

1.07e-052114222573740
Pubmed

Dependence of cell survival on correlative activities of xanthine oxidase and dihydopyrimidine dehydrogenase in human brain-derived cell culture.

DPYD XDH

1.07e-052114223597150
Pubmed

PI4KA and PIKfyve: Essential phosphoinositide signaling enzymes involved in myriad human diseases.

PIKFYVE PI4KA

1.07e-052114237453227
Pubmed

A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration.

MRPL30 OGDH OGDHL

1.52e-0515114330737405
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MPP3 ANKS6 SETD1B ZDHHC5 SRCAP LYST PIKFYVE UNC119 SNX30 PI4KA OGDHL RIC8A CRAMP1 TRAPPC9

1.61e-0511051141435748872
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

RNF213 SRCAP CHAMP1 GATAD2B MED24 NOP14 KDM2A GREB1

1.76e-05341114832971831
Pubmed

Human transcription factor protein interaction networks.

ASXL1 DHX37 MYO18A KLF15 LBR SRCAP GATAD2B STAU1 MED24 PBRM1 NOP14 MRPL16 DPF3 ZBTB21 ASXL2 TRAPPC9

1.76e-0514291141635140242
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ELOA MYO18A SYNPO SRCAP OGDH LYST PRX PPL NOP14 KIAA0825 BAZ1A SH3PXD2A TKT ZBTB21 OGDHL MYBPC1

1.96e-0514421141635575683
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

ELOA RNF213 CHAMP1 GATAD2B POLR3A CSDE1 MED24 PBRM1 BAZ1A TKT ZBTB21 KDM2A DNMT1

2.92e-0510141141332416067
Pubmed

Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}.

ASXL1 ASXL2

3.19e-053114221047783
Pubmed

Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family.

ASXL1 ASXL2

3.19e-053114216412590
Pubmed

Functional proteomics of the epigenetic regulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics for translational medicine.

ASXL1 ASXL2

3.19e-053114225835095
Pubmed

ASXL2 mutations are frequently found in pediatric AML patients with t(8;21)/ RUNX1-RUNX1T1 and associated with a better prognosis.

ASXL1 ASXL2

3.19e-053114228063196
Pubmed

Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting Multiple Independent Domains.

ASXL1 ASXL2

3.19e-053114229284740
Pubmed

Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase.

ASXL1 ASXL2

3.19e-053114233731362
Pubmed

Understanding the phenotypic spectrum of ASXL-related disease: Ten cases and a review of the literature.

ASXL1 ASXL2

3.19e-053114233751773
Pubmed

Molecular analysis of human solute carrier SLC26 anion transporter disease-causing mutations using 3-dimensional homology modeling.

SLC26A3 SLC26A4

3.19e-053114228941661
Pubmed

Multidimensional Proteomics Reveals a Role of UHRF2 in the Regulation of Epithelial-Mesenchymal Transition (EMT).

GATAD2B PBRM1 KDM2A DNMT1

3.28e-0555114427114453
Pubmed

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.

ASXL1 SETD1B ASXL2

3.75e-0520114329785026
Pubmed

Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator.

MYO18A CHAMP1 BAZ1A DNMT1

5.62e-0563114425680957
Pubmed

BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion.

ASXL1 ASXL2

6.36e-054114234170818
Pubmed

MIP-T3 associates with IL-13Ralpha1 and suppresses STAT6 activation in response to IL-13 stimulation.

IL13RA1 TRAF3IP1

6.36e-054114212935900
Pubmed

Oncogenic Truncations of ASXL1 Enhance a Motif for BRD4 ET-Domain Binding.

ASXL1 ASXL2

6.36e-054114234536441
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SYNPO SLC7A6 CHAMP1 HECW2 ZBTB21 IGSF9 HHIPL1 HPS5 CRAMP1

6.42e-05529114914621295
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

SLC26A3 TTLL3 TMPRSS4 SYNPO SLC7A6 SLC7A9 CSDE1 FSD1L BMX ANKEF1 ZBTB21 OGDHL HYDIN MYBPC1

8.79e-0512931141415342556
Pubmed

Differential expression of C-protein isoforms in developing and degenerating mouse striated muscles.

MYBPC1 MYBPC3

1.06e-045114210024132
Pubmed

Isoform transitions of the myosin binding protein C family in developing human and mouse muscles: lack of isoform transcomplementation in cardiac muscle.

MYBPC1 MYBPC3

1.06e-04511429440711
Pubmed

Replication of the five novel loci for uric acid concentrations and potential mediating mechanisms.

CARMIL1 GCKR

1.06e-045114219861489
Pubmed

Analysis of atherosclerosis susceptibility in mice with genetic defects in platelet function.

LYST HPS5

1.06e-04511422369371
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

RNF213 SRCAP CHAMP1 GATAD2B PBRM1 BAZ1A DNMT1

1.17e-04332114732786267
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CARMIL1 LBR LYST UNC119 BMX SH3PXD2A PI4KA ZBTB21 SSH2 TRAPPC9 DNMT1

1.28e-048611141136931259
Pubmed

Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger.

SLC26A3 SLC26A4

1.58e-046114211087667
Pubmed

Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9.

SLC26A3 SLC26A4

1.58e-046114211834742
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

SETD1B SRCAP PBRM1 DPF3 DNMT1

1.74e-04157114530186101
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

SETD1B RPS6KA5 STAU1 SCUBE1 PBRM1 PI4KA TRAPPC9 DNMT1

1.78e-04475114831040226
Pubmed

A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects.

SETD1B RIC8A ARHGEF3

1.91e-0434114324026423
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

ELOA DHX37 STAU1 SCYL2 PBRM1 NOP14 TKT UTP20

1.99e-04483114836912080
Pubmed

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.

GATAD2B BAZ1A

2.21e-047114226816381
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZDHHC5 RNF213 GATAD2B PRX PIKFYVE KDM2A SSH2 TRAPPC9

2.28e-04493114815368895
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ELOA CARMIL1 SRCAP CHAMP1 STAU1 SCYL2 CSDE1 BAZ1A TKT ZBTB21 DNMT1

2.57e-049341141133916271
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ANKS6 EMC3 LBR LYST PIKFYVE SNX30 PI4KA TRIM13

2.65e-04504114834432599
Pubmed

CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes.

SETD1B DNMT1

2.94e-048114218680430
Pubmed

The Inv compartment of renal cilia is an intraciliary signal-activating center to phosphorylate ANKS6.

ANKS6 UNC119

2.94e-048114229395339
Pubmed

Predictive value of 8 genetic loci for serum uric acid concentration.

CARMIL1 GCKR

2.94e-048114220162742
Pubmed

Common variants in SLC17A3 gene affect intra-personal variation in serum uric acid levels in longitudinal time series.

CARMIL1 GCKR

2.94e-048114220162743
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZDHHC5 KLF15 SRCAP GATAD2B ZNF710 PBRM1 BAZ1A DPF3 ZBTB21 DNMT1

3.36e-048081141020412781
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ASXL1 PIKFYVE KDM2A HPS5

3.63e-04102114410231032
Pubmed

Gene duplication and neofunctionalization: POLR3G and POLR3GL.

POLR3GL POLR3A

3.78e-049114224107381
Pubmed

The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.

ASXL1 ASXL2

3.78e-049114226416890
Pubmed

Metabolic activation-related CD147-CD98 complex.

SLC7A6 SLC7A9

3.78e-049114215901826
Pubmed

Physiological roles and regulation of mammalian sulfate transporters.

SLC26A3 SLC26A4

3.78e-049114211581495
Pubmed

Additional sex combs-like family genes are required for normal cardiovascular development.

ASXL1 ASXL2

3.78e-049114224860998
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

ELOA IL13RA1 SETD1B MED24 PTCHD1 PACRGL PBRM1 TKT CDK5RAP1 KDM2A RIC8A SSH2 CRAMP1

4.17e-0413271141332694731
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

ASXL1 TRAF3IP1 CARMIL1 XDH IDE CHAMP1 PPL CSDE1 PBRM1 MRPL16 TKT ASXL2

4.18e-0411551141220360068
Pubmed

An atlas of genetic influences on human blood metabolites.

GCKR SLC7A6 SLC7A9 TKT HPS5

4.19e-04190114524816252
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

CHAMP1 HHIPL1 FRMPD3 HYDIN

4.36e-04107114411347906
Pubmed

ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer.

ASXL1 ASXL2

4.71e-0410114232669118
Pubmed

N-glycosylation and topology of the human SLC26 family of anion transport membrane proteins.

SLC26A3 SLC26A4

4.71e-0410114224647542
Pubmed

Comparison of chemical carcinogen skin tumor induction efficacy in inbred, mutant, and hybrid strains of mice: morphologic variations of induced tumors and absence of a papillomavirus cocarcinogen.

LBR LYST

4.71e-041011429328433
Pubmed

The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.

ASXL1 ASXL2

4.71e-0410114219815555
Pubmed

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.

CARMIL1 GCKR

4.71e-0410114219503597
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FOXR1 ASXL1 GATAD2B NOP14 BAZ1A PI4KA ZBTB21 UTP20 KDM2A ASXL2

5.31e-048571141025609649
Pubmed

A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells.

PRX PPL

5.75e-0411114214625392
Pubmed

Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease.

CARMIL1 GCKR

5.75e-0411114219890391
Pubmed

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.

RNF213 CHAMP1 STAU1 DNMT1

5.91e-04116114421282530
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

MYO18A ZDHHC5 STAU1 SCYL2 CSDE1 PBRM1 NOP14 CDK5RAP1 TRIM13

6.18e-04719114935337019
Pubmed

Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase.

OGDH OGDHL

6.88e-0412114225438054
Pubmed

Molecular diversity of myofibrillar proteins: gene regulation and functional significance.

MYBPC1 MYBPC3

6.88e-041211428618961
Pubmed

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.

MRPL16 BAZ1A TRIM13

7.53e-0454114326288249
Pubmed

Functional proteomics mapping of a human signaling pathway.

GATAD2B PPL STAU1 SCYL2 PBRM1 BAZ1A KDM2A ASXL2

7.55e-04591114815231748
Pubmed

Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

DHX37 LBR OGDH POLR3A CSDE1 UTP20 RIC8A

7.65e-04454114733226137
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

ASXL1 EXTL1 PRX CSDE1 BMX SNX12

7.76e-04329114617474147
Pubmed

ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.

DHX37 LBR GATAD2B STAU1 PBRM1 NOP14

7.88e-04330114633301849
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

ASXL1 SLC25A21 ANKS6 TTLL3 DCDC2C CARMIL1 IDE OGDH SH3PXD2A HECW2 TRAPPC9 RAPGEFL1

7.91e-0412421141230973865
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DHX37 IDE LBR OGDH POLR3A STAU1 PBRM1 BAZ1A TKT PI4KA UTP20 DNMT1 MYBPC1

8.10e-0414251141330948266
Pubmed

Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation.

ELOA BMX

8.11e-0413114215207703
Pubmed

Loss of the tumor suppressor BAP1 causes myeloid transformation.

ASXL1 ASXL2

8.11e-0413114222878500
Pubmed

TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF.

MYBPC1 MYBPC3

8.11e-0413114216052631
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

RNF213 STAU1 PBRM1 TKT UTP20 DDX60L

8.13e-04332114625693804
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

IL31RA RPS6KA5 MRPL30 LYST GATAD2B PRX UNC119 SH3PXD2A DDX60L CPLANE1

8.41e-049101141036736316
Pubmed

Human metabolic individuality in biomedical and pharmaceutical research.

GCKR SLC7A6 HPS5

8.82e-0457114321886157
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

GATAD2B STAU1 NOP14 BAZ1A UTP20 DNMT1

1.05e-03349114625665578
Pubmed

Nucleosome-interacting proteins regulated by DNA and histone methylation.

ZBTB21 KDM2A

1.09e-0315114221029866
Pubmed

Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells.

SLC15A4 HPS5

1.09e-0315114221045126
Pubmed

Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.

PBRM1 DPF3

1.09e-0315114223785148
Pubmed

An essential switch in subunit composition of a chromatin remodeling complex during neural development.

PBRM1 DPF3

1.09e-0315114217640523
Pubmed

Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1.

STAU1 DNMT1

1.09e-0315114227030811
Pubmed

EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos.

TRIM13 DNMT1

1.09e-0315114226576615
Pubmed

Platelet storage pool deficiency in mouse pigment mutations associated with seven distinct genetic loci.

LYST HPS5

1.09e-031511426696991
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

ELOA OGDH PPL CSDE1 TKT KDM2A

1.23e-03360114633111431
Pubmed

Interferon-induced SCYL2 limits release of HIV-1 by triggering PP2A-mediated dephosphorylation of the viral protein Vpu.

RPS6KA5 SCYL2

1.24e-0316114223047923
InteractionZNF330 interactions

ELOA DHX37 KLF15 STAU1 PBRM1 NOP14 BAZ1A TKT ZBTB21 UTP20 KDM2A DNMT1

7.82e-0644611312int:ZNF330
GeneFamilyFibronectin type III domain containing

IL31RA FSD1L IGSF9 USH2A MYBPC1 MYBPC3

4.22e-05160726555
GeneFamilySolute carriers

SLC25A21 SLC26A3 SLC35D2 SLC26A4 FLVCR2 SLC7A6 SLC7A9 SLC15A4

1.71e-04395728752
GeneFamilyFibronectin type III domain containing|I-set domain containing|Myosin binding proteins

MYBPC1 MYBPC3

4.31e-048722658
GeneFamilyZinc fingers CXXC-type

KDM2A DNMT1

1.01e-0312722136
GeneFamilyPDZ domain containing

MPP3 MYO18A PRX FRMPD3

3.17e-031527241220
CoexpressionGSE27291_0H_VS_6H_STIM_GAMMADELTA_TCELL_DN

FOXR1 ANKS6 SLC35D2 PPL CSDE1 UNC119 UTP20 ASXL2

2.22e-061961138M8453
CoexpressionGSE27786_BCELL_VS_ERYTHROBLAST_DN

MPP3 IL13RA1 SLC26A3 IL31RA FLVCR2 OGDH SLC7A9

2.64e-052001137M4811
CoexpressionGSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_DN

MRPL30 RNF213 NRP1 SCYL2 SLC15A4 CDK5RAP1 HPS5

2.64e-052001137M7347
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL13RA1 PLEKHG7 CARMIL1 MRPL30 BMX OGDHL

4.74e-0616811468072d0496b7b730c4601009eaa69ec5366d26d73
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUP210L SYNPO PRX HECW2 HHIPL1 GREB1

5.42e-061721146073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

MPP3 CARMIL1 FLVCR2 PPL OGDHL HPS5

1.21e-05198114685f424cd9bb3117c9e322031024aabb87696ce47
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate|GW23 / Sample Type, Dataset, Time_group, and Cell type.

TTLL3 SLC35D2 SLC26A4 ANKEF1 DDX60L USH2A

1.28e-052001146fe772d98c461c973dfc082e1fc50117c27ced804
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL13RA1 PLEKHG7 CARMIL1 BMX OGDHL

5.91e-051611145f5df8c6a340d5026726804b103e32137f363ca40
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHG7 MRPL30 PTCHD1 BMX OGDHL

6.09e-0516211450ccdb224ee3c585a6d0caffde5608d9d3cc452f8
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHG7 MRPL30 PTCHD1 BMX OGDHL

6.09e-0516211450d35752a7249b3c62b8007ec8a775c37d16b8d31
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHG7 MRPL30 PTCHD1 BMX OGDHL

6.09e-0516211459ccee8e7e78e16b0149a94867e12d86d3b04f9b9
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC26A3 FLVCR2 BAZ1A TKT UTP20

6.09e-051621145d712bc31840ad1523e3dbf884acbb428a8995001
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IL31RA DMRT3 IGSF9 HYDIN

6.16e-058311441ab68323518adc7fd0a459b41fad12d60f97eb5c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR-CR_Lhx5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IL31RA DMRT3 IGSF9 HYDIN

6.16e-0583114475b27d91a4473286f4b40027e96ac5246f5abe5b
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

JAKMIP2 C3orf33 PBRM1 BAZ1A HYDIN

6.64e-051651145436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

JAKMIP2 C3orf33 PBRM1 BAZ1A HYDIN

6.64e-051651145242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL13RA1 MRPL30 PTCHD1 BMX OGDHL

7.43e-05169114505e12524d68d409fed386ffad233305683b4575b
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-3|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS4 PPL XRRA1 RAPGEFL1 MYBPC3

8.53e-05174114576310c0af1d7df6a4de3816838b2ac2892f68746
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Tuft|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL13RA1 PLEKHG7 CARMIL1 BMX OGDHL

9.49e-051781145f17c3b7bb562ac24c6a03fe3c9ba94c2b434c141
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

PLEKHG7 TMPRSS4 RNF213 EXTL1 DDX60L

9.49e-051781145ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCellE17.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PRX NRP1 HECW2 ARHGEF3 USH2A

9.49e-051781145982205ba117a4c7b7e9b713689a5b69190f0bca9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPYD RPS6KA5 SLC26A4 PPL NRP1

9.75e-051791145747a32460b257fffca30527b56a74720eb9c12e4
ToppCelldroplet-Fat-Bat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP3 ANKS6 SYNPO PRX HECW2

9.75e-051791145e6224864eb76a2e9c1fc0c61513d9e936bb5c72c
ToppCelldroplet-Fat-Bat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP3 ANKS6 SYNPO PRX HECW2

9.75e-0517911459863ab3ceb160a4b1d9790033a4ac48845863d65
ToppCelldroplet-Fat-Bat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP3 ANKS6 SYNPO PRX HECW2

9.75e-051791145dfe110add7228cd834b35916cbcc849769a01bb9
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RNF213 PRX NRP1 HECW2 ARHGEF3

1.08e-041831145e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCelldroplet-Tongue-nan-24m-Epithelial-keratinocyte|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MFSD6 ZDHHC5 TMPRSS4 IDE PPL

1.08e-0418311459e6c96ada930e8559246a270dfc69fb3cbb3bdf3
ToppCellPBMC-Mild-cDC_9|Mild / Compartment, Disease Groups and Clusters

RNF213 PPL SCUBE1 UTP20 DDX60L

1.11e-0418411452e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL13RA1 MRPL30 PTCHD1 BMX OGDHL

1.14e-041851145686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL13RA1 CARMIL1 MRPL30 BMX OGDHL

1.14e-04185114501d0e848d8ede2745cfb10b070e2d9674ef4d477
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

CARMIL1 ZNF710 SH3PXD2A GREB1 TRAPPC9

1.17e-041861145de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MPP3 CARMIL1 FLVCR2 PPL TRIM13

1.17e-0418611453aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

CARMIL1 ZNF710 SH3PXD2A GREB1 TRAPPC9

1.17e-0418611450b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

TRAF3IP1 IDE CHAMP1 PBRM1 ASXL2

1.17e-04186114503db813598b67b1e08f759758a1c2023396921fa
ToppCellControl-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

MPP3 PRX NRP1 HECW2 ARHGEF3

1.23e-04188114588b3415e33db81726dd29c1f50c886e057af50a0
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL13RA1 PLEKHG7 CARMIL1 BMX OGDHL

1.32e-04191114554f07e4de61735051498846afb44b1798bed8144
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NUP210L C1orf87 XDH ACSBG2 USH2A

1.39e-041931145315840bc48899f3a36d57b19197509de19716e3d
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LBR LYST BMX BAZ1A TKT

1.39e-041931145e1855cff9a6bcfda9188b9fdf6c9d698405da990
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XDH PRX NRP1 HECW2 ARHGEF3

1.42e-041941145f159ef8541d75a4e98468947f231bb463bec922c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TMPRSS4 RNF213 PPL SSH2 HYDIN

1.42e-041941145e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

PLEKHG7 RNF213 BAZ1A DDX60L ARHGEF3

1.45e-041951145b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHG7 SLC26A4 TMPRSS4 XDH RNF213

1.45e-0419511453f8ed20ad17afe1545e574e5ca5fe33c3704c7f3
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 TMPRSS4 PPL CPLANE1 HYDIN

1.53e-0419711455c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCellBL|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DPYD RNF213 LYST BAZ1A DDX60L

1.53e-0419711451acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCellControl-PLT_4|Control / Disease Group and Platelet Clusters

ELOA LBR GATAD2B DPF3 TRIM13

1.56e-041981145387fd3037fd52e4d4c42de0588767e58af228b59
ToppCellLPS_only-Epithelial_airway-airway_epithelial|LPS_only / Treatment groups by lineage, cell group, cell type

C1orf87 TMPRSS4 JAKMIP2 HYDIN MYBPC1

1.56e-041981145e035380578c01b0243bfef29ca9b50cc17cce771
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPEGNB SYNPO SRCAP NRP1 ASB6

1.56e-041981145399760b6b6fef8639ded53b14f251b9fce600e81
ToppCellLPS_only-Epithelial_airway|LPS_only / Treatment groups by lineage, cell group, cell type

C1orf87 TMPRSS4 JAKMIP2 HYDIN MYBPC1

1.56e-041981145ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMPRSS4 PPL TKT IGSF9 RAPGEFL1

1.56e-04198114522935a8afac54021f68b5f7a5accf51523e2f336
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRAF3IP1 PLEKHG7 TMPRSS4 CPLANE1 HYDIN

1.56e-041981145d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Airway-Club|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

C1orf87 TMPRSS4 XDH JAKMIP2 MYBPC1

1.60e-0419911458649c2380285a668782d75eb076ce548eed0911d
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MFSD6 TMPRSS4 PPL SH3PXD2A CPLANE1

1.64e-04200114597f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

C1orf87 TMPRSS4 XDH JAKMIP2 HYDIN

1.64e-042001145da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

IRX3 FLVCR2 FSD1L OGDHL IGSF9

1.64e-042001145eac33be484dc443794e66e473f03e98406c2983e
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

RNF213 SRCAP JAKMIP2 BTN3A3 ARHGEF3

1.64e-0420011452281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

C1orf87 TMPRSS4 XDH JAKMIP2 HYDIN

1.64e-04200114572c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
DrugICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A_EA

ELOA SLC35D2 NRP1 ANKEF1 UTP20 KDM2A GREB1 RAPGEFL1

3.58e-0618211381043_DN
DiseaseIGF-1 measurement

CARMIL1 GCKR SRCAP OGDH MED24 ASXL2 DDX60L HPS5 CRAMP1 DNMT1 MYBPC3

2.65e-0648811211EFO_0004627
Diseaseoxoglutarate dehydrogenase deficiency (implicated_via_orthology)

OGDH OGDHL

1.43e-0521122DOID:0081326 (implicated_via_orthology)
Diseasesignal peptide, CUB and EGF-like domain-containing protein 1 measurement

GCKR SCUBE1

8.53e-0541122EFO_0803074
Diseaseneuropilin-1 measurement

GCKR NRP1

2.96e-0471122EFO_0020603
Diseaselysine measurement

SLC7A6 SLC7A9 DPF3

3.76e-04371123EFO_0005002
Diseasemonocyte count

ASXL1 CARMIL1 GCKR OGDH LYST MED24 BAZ1A TKT PI4KA SSH2 DNMT1 RAPGEFL1 MYBPC1 MYBPC3

4.81e-04132011214EFO_0005091
Diseaseornithine measurement

SLC7A6 OGDH SLC7A9

6.29e-04441123EFO_0009776
Diseasephosphatidylcholine 34:1 measurement

GCKR JAKMIP2

7.68e-04111122EFO_0010375
Diseaselevel of Diacylglycerol (18:1_18:1) in blood serum

GCKR B4GALNT2

7.68e-04111122OBA_2045170
Diseasecortical thickness

NUP210L GATAD2B STAU1 NRP1 SCUBE1 DMRT3 KIAA0825 BAZ1A SH3PXD2A PI4KA IGSF9 SSH2

1.08e-03111311212EFO_0004840
Diseasetriacylglycerol 46:2 measurement

GCKR JAKMIP2

1.26e-03141122EFO_0010402
Diseaseplatelet storage pool deficiency (implicated_via_orthology)

LYST HPS5

1.45e-03151122DOID:2223 (implicated_via_orthology)
Diseasemean platelet volume

MPP3 SETD1B SLC35D2 NUP210L CARMIL1 GCKR SRCAP ZNF710 PI4KA ARHGEF3 MYBPC3

1.74e-03102011211EFO_0004584
Diseaselung non-small cell carcinoma (is_implicated_in)

NRP1 PBRM1 KDM2A DNMT1

1.98e-031391124DOID:3908 (is_implicated_in)
Diseasecognitive function measurement, self reported educational attainment

DPYD SLC35D2 PLEKHG7 CARMIL1 GATAD2B STAU1

2.39e-033551126EFO_0004784, EFO_0008354
Diseasetriacylglycerol 48:2 measurement

GCKR JAKMIP2

3.14e-03221122EFO_0010405
Diseasemean corpuscular hemoglobin concentration

SETD1B SLC35D2 CARMIL1 MRPL30 ZDHHC5 GCKR LBR BAZ1A HECW2 RIC8A ASXL2

3.23e-03110511211EFO_0004528

Protein segments in the cluster

PeptideGeneStartEntry
PIPVETLVKKKIPII

ACSBG2

526

Q5FVE4
LIPPVKATPLKRFSQ

ARHGEF3

51

Q9NR81
NLKLPEPPRKVGIFL

BTN3A3

451

O00478
EPSEPEIEIKLPKLR

DNMT1

1126

P26358
AKFPVTIRHPVIPKL

B4GALNT2

296

Q8NHY0
FPDRVLKIPRAVPVL

BMX

166

P51813
KGKFVLPLPICVIPE

ANKEF1

426

Q9NU02
DPLPGRIKVDFVIPK

CSDE1

281

O75534
CFIPKRPIPTIKDVI

DPYD

911

Q12882
PVDVKVKALPLPDRL

ASB6

391

Q9NWX5
EPKVPPIRIQLSRIK

ASXL1

566

Q8IXJ9
IQVRKVPPLKIPVSR

ASXL2

611

Q76L83
DLKELPEPTPVKTRL

BAZ1A

406

Q9NRL2
PLKPLKIRPVSQPFV

C1orf87

446

Q8N0U7
REVEVKLTPLILKPF

LBR

111

Q14739
RPIIKRFLGKLTIPV

HECW2

271

Q9P2P5
ILPPILAETPKRAVK

SLC25A21

76

Q9BQT8
FRKPIVPQKEPSPLL

PBRM1

1291

Q86U86
VIRRPPLTEKLLSKP

TRAF3IP1

16

Q8TDR0
RSSKPIKRPVLDPFI

JAKMIP2

421

Q96AA8
EEKPLPIRPLKTTLR

KIAA0825

1166

Q8IV33
KACRQPPIVFLPKLV

GREB1

1251

Q4ZG55
KTEPPKIFRVKPVLG

IL31RA

121

Q8NI17
RLIPFVPKEKFIPKT

HHIPL1

596

Q96JK4
PKLRLLEIKPEVELP

DPF3

91

Q92784
LKFLPVPKAPEIDPV

FSD1L

191

Q9BXM9
KEKAIFPPRILSTRP

KIAA1109

4876

Q2LD37
KKLLSLPPLPVITLR

HPS5

261

Q9UPZ3
IPLPKIKRLLASSVP

DDX60L

1326

Q5H9U9
KKPAFLVPIVPLSFI

PLGRKT

76

Q9HBL7
QILLPFRKPLIIFTP

OGDHL

831

Q9ULD0
LVTKKFPVDLRLPPV

MYO18A

196

Q92614
LKYRRETPLKPIPVE

PPL

391

O60437
LPPIKEAKPRLQKLF

PI4KA

781

P42356
PAKPVIPTAAKRIDL

GLRB

461

P48167
LAAKKVPAPFKPVIR

RPS6KA5

326

O75582
LRKQLEKTLLEIPPP

GATAD2B

356

Q8WXI9
FVKPATLRCVPKIRP

MFSD6

151

Q6ZSS7
EKSKPVPLKLFTPRL

NOP14

756

P78316
VPLKLFTPRLVKVLE

NOP14

761

P78316
YLKRLKIIIFPPIPD

IL13RA1

366

P78552
PIPLKKLFPSIISIT

GCKR

446

Q14397
PKPLITRFVRIKPAT

NRP1

396

O14786
ILLPFRKPLIIFTPK

OGDH

846

Q02218
CVPLPKIFIKRQAPL

PIKFYVE

1391

Q9Y2I7
KLEVIFAPKKRVPPF

HYDIN

4486

Q4G0P3
KLKFPTRPKVRVPTI

KDM2A

521

Q9Y2K7
PPIRKVAEIFVKAFP

CPLANE1

1356

Q9H799
LAKLRKVPDVLPVLP

ELOA

496

Q14241
LFIPPAKIIIPKFSL

DCDC2C

146

A8MYV0
KANRPPLEVLKKIFP

DMRT3

246

Q9NQL9
KPVLSIDTEPRKPAL

CHAMP1

516

Q96JM3
LPKEVRLSPKLILDP

FRMPD3

966

Q5JV73
KELERPIKVPVVIPV

SLC7A9

401

P82251
DQKPVRLPLKVPIEL

CRAMP1

311

Q96RY5
LARYKLRIVKPPKLP

FOXR1

21

Q6PIV2
LTRLPSDKLKAVIPP

ANKS6

546

Q68DC2
LAPPILELREKLKPE

ELMO3

516

Q96BJ8
IPITLPIIASLRKEP

C3orf33

96

Q6P1S2
ILVIIVFKEKPKYPP

FLVCR2

266

Q9UPI3
PVREITFPKSNKPII

LYST

3741

Q99698
SKFVRIAPVPIAAKP

KLF15

276

Q9UIH9
LLPPVLKKVPSDKER

CARMIL1

1296

Q5VZK9
TEFKRGLPLFPLVKP

IDE

996

P14735
VTTKVPFPLTLRFKP

EMC3

136

Q9P0I2
RLFAKPPPVIKVESR

DHX37

421

Q8IY37
PPKRRILIVVPEIFL

SCUBE1

831

Q8IWY4
KALVKIVPVFLALIP

SLC15A4

316

Q8N697
VFPPFRLLPEKMTLI

NUP210L

1081

Q5VU65
KGAPEKAIPLLPRLI

PACRGL

146

Q8N7B6
KAIPLLPRLIPVLKA

PACRGL

151

Q8N7B6
KKLLKTAFQPVPRRP

IRX3

471

P78415
IFVKPAIQEKRKTPP

MPP3

501

Q13368
EKPKLRFIERAPLVP

MRPL16

46

Q9NX20
KIHKEPYIRERPPLV

USH2A

5066

O75445
PHIRPLEKEKVIPLV

UTP20

526

O75691
KERITILLPKRPPKT

POLR3GL

126

Q9BT43
FDKKIPVKLFPLPLL

SLC35D2

86

Q76EJ3
SKPRNKRVPILPFVI

ERVW-1

311

Q9UQF0
SKIVVPPLPGKALKR

SNX12

86

Q9UMY4
LIRIKPLKLPQGLPA

MRPL30

116

Q8TCC3
ILPVILTFLPPSKKK

PTCHD1

841

Q96NR3
FVLSPIKEPAKVSPR

SYNPO

816

Q8N3V7
LPPKRPIKEVLTDIF

MED24

701

O75448
DEKIKVRLPPPTILK

POLR3A

576

O14802
LPKVLPKLPKRVIVQ

SCYL2

356

Q6P3W7
AIRLPSFKVKRKEPP

SETD1B

956

Q9UPS6
KGPPRVLEPLKDVVL

SPEGNB

51

A0A087WV53
RFKDKLPVPIPIEFI

SLC26A3

281

P40879
SLVPPLETEKLPRKR

SRCAP

3126

Q6ZRS2
RPARKFLKAQVLPPL

RIC8A

346

Q9NPQ8
FIVAAVTKLPPIKVP

EXTL1

591

Q92935
VKKLSEQVFLPPRPP

CDK5RAP1

286

Q96SZ6
IFPKVTCRPPKEVID

RNF213

2126

Q63HN8
LINIIKPPVRDPKGF

RNF213

4601

Q63HN8
KALELALKRPRPPVL

ZBTB21

266

Q9ULJ3
VLFEIKKPPVSERLP

UNC119

101

Q13432
REKIKVIKETPLPPS

TRIM13

256

O60858
VLDPFTIKPLDRKLI

TKT

531

P29401
LEELKKLPPLPAVER

STAU1

246

O95793
VPLPLPKRVEIIEYT

SSH2

1001

Q76I76
RFRHKIPVPIPIEVI

SLC26A4

291

O43511
LIPPLPEKFVVKGVV

SNX30

151

Q5VWJ9
DPKQRIIPFLPGKIL

SH3PXD2A

66

Q5TCZ1
KLPKVPEAALPEVRL

PRX

451

Q9BXM0
LNSLDVKPLRKPRIP

TMPRSS4

11

Q9NRS4
PPVRLVPKVKFEKVE

ZNF710

101

Q8N1W2
IFPPELLRLKDTPRK

XDH

211

P47989
KVAPSILKPRKAPAL

TTLL3

631

Q9Y4R7
RVLLKAPPAFIERPK

IGSF9

411

Q9P2J2
PKRPRPLKLSVFFPI

SLC7A6

416

Q92536
PKKEKTIVIRPPFLR

ZDHHC5

256

Q9C0B5
PIPLDRLVVKSIEPL

PLEKHG7

606

Q6ZR37
PVPFTKLPIVRHVKL

TRAPPC9

531

Q96Q05
PVIPFVPLILKDLTF

RAPGEFL1

571

Q9UHV5
SLPPIFEILPVKSLK

XRRA1

346

Q6P2D8
QPILVKEIIEPPKIR

MYBPC1

826

Q00872
ELFVKEPPVLITRPL

MYBPC3

446

Q14896