Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnetrin receptor activity

UNC5D UNC5B UNC5C

1.37e-076393GO:0005042
GeneOntologyMolecularFunctionsemaphorin receptor binding

SEMA5A SEMA3C SEMA5B

1.19e-0523393GO:0030215
GeneOntologyMolecularFunctionchemorepellent activity

SEMA5A SEMA3C SEMA5B

2.43e-0529393GO:0045499
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

ADGRB3 TMIGD3 VIPR2 CD72 SEMA5A TRPV1 OSMR UNC5D UNC5B UNC5C

2.04e-0413533910GO:0004888
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

SEMA5A LIPC

1.46e-0329392GO:0043395
GeneOntologyMolecularFunctionglycosaminoglycan binding

SEMA5A THBS2 LIPC ADAMTSL5

1.80e-03268394GO:0005539
GeneOntologyBiologicalProcessnetrin-activated signaling pathway

UNC5D UNC5B UNC5C

5.21e-079393GO:0038007
GeneOntologyBiologicalProcessnegative chemotaxis

SEMA5A SEMA3C SEMA5B UNC5C

2.56e-0651394GO:0050919
GeneOntologyBiologicalProcessaxon guidance

SEMA5A SEMA3C SEMA5B UNC5D UNC5B UNC5C

1.47e-05285396GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

SEMA5A SEMA3C SEMA5B UNC5D UNC5B UNC5C

1.50e-05286396GO:0097485
GeneOntologyBiologicalProcessanterior/posterior axon guidance

UNC5B UNC5C

7.27e-057392GO:0033564
GeneOntologyBiologicalProcesssemaphorin-plexin signaling pathway

SEMA5A SEMA3C SEMA5B

1.30e-0452393GO:0071526
GeneOntologyBiologicalProcessneural crest cell migration

SEMA5A SEMA3C SEMA5B

2.19e-0462393GO:0001755
GeneOntologyBiologicalProcessmesenchymal cell migration

SEMA5A SEMA3C SEMA5B

2.40e-0464393GO:0090497
GeneOntologyBiologicalProcessoligosaccharide catabolic process

MAN2C1 LCT

4.11e-0416392GO:0009313
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

ADGRB3 SEMA5A SEMA3C SEMA5B UNC5D UNC5B UNC5C

4.48e-04748397GO:0048667
MousePhenoincreased coronary flow rate

TMIGD3 TRPV1

3.86e-054362MP:0003022
DomainTSP_1

ADGRB3 ADAMTS18 SEMA5A THBS2 THSD1 ADAMTSL5 SEMA5B SSPOP UNC5D UNC5B UNC5C

2.04e-19633711PF00090
DomainTSP1

ADGRB3 ADAMTS18 SEMA5A THBS2 THSD1 ADAMTSL5 SEMA5B SSPOP UNC5D UNC5B UNC5C

2.96e-19653711SM00209
DomainTSP1_rpt

ADGRB3 ADAMTS18 SEMA5A THBS2 THSD1 ADAMTSL5 SEMA5B SSPOP UNC5D UNC5B UNC5C

2.96e-19653711IPR000884
DomainTSP1

ADGRB3 ADAMTS18 SEMA5A THBS2 THSD1 ADAMTSL5 SEMA5B SSPOP UNC5D UNC5B UNC5C

2.96e-19653711PS50092
DomainUPA

UNC5D UNC5B UNC5C

7.14e-085373IPR033772
DomainUPA

UNC5D UNC5B UNC5C

7.14e-085373PF17217
DomainZU5

UNC5D UNC5B UNC5C

5.96e-079373SM00218
DomainZU5

UNC5D UNC5B UNC5C

8.51e-0710373PS51145
DomainZU5

UNC5D UNC5B UNC5C

1.56e-0612373PF00791
DomainZU5_dom

UNC5D UNC5B UNC5C

1.56e-0612373IPR000906
DomainSemaphorin

SEMA5A SEMA3C SEMA5B

7.97e-0620373IPR027231
DomainDEATH

UNC5D UNC5B UNC5C

2.03e-0527373SM00005
DomainSema

SEMA5A SEMA3C SEMA5B

3.10e-0531373SM00630
DomainSemap_dom

SEMA5A SEMA3C SEMA5B

3.10e-0531373IPR001627
DomainSema

SEMA5A SEMA3C SEMA5B

3.10e-0531373PF01403
DomainSEMA

SEMA5A SEMA3C SEMA5B

3.10e-0531373PS51004
DomainIg_I-set

LRRC4B SEMA3C UNC5D UNC5B UNC5C

3.46e-05190375IPR013098
DomainI-set

LRRC4B SEMA3C UNC5D UNC5B UNC5C

3.46e-05190375PF07679
DomainDeath

UNC5D UNC5B UNC5C

3.75e-0533373PF00531
DomainDeath_domain

UNC5D UNC5B UNC5C

5.76e-0538373IPR000488
DomainDEATH_DOMAIN

UNC5D UNC5B UNC5C

5.76e-0538373PS50017
DomainK_chnl_volt-dep_Kv9

KCNS3 KCNV2

7.97e-057372IPR003971
DomainPSI

SEMA5A SEMA3C SEMA5B

8.96e-0544373IPR016201
DomainPSI

SEMA5A SEMA3C SEMA5B

1.02e-0446373SM00423
Domain-

TMIGD3 LRRC4B SEMA3C OSMR UNC5D UNC5B UNC5C

2.80e-046633772.60.40.10
DomainIg-like_fold

TMIGD3 LRRC4B SEMA3C OSMR UNC5D UNC5B UNC5C

4.09e-04706377IPR013783
DomainIg-like_dom

TMIGD3 LRRC4B SEMA3C UNC5D UNC5B UNC5C

4.23e-04503376IPR007110
Domain-

UNC5D UNC5B UNC5C

8.21e-04933731.10.533.10
DomainADAM_spacer1

ADAMTS18 ADAMTSL5

9.41e-0423372IPR010294
DomainADAM_spacer1

ADAMTS18 ADAMTSL5

9.41e-0423372PF05986
DomainDEATH-like_dom

UNC5D UNC5B UNC5C

9.85e-0499373IPR011029
DomainPeptidase_M12B_ADAM-TS

ADAMTS18 ADAMTSL5

1.03e-0324372IPR013273
DomainHormR

ADGRB3 VIPR2

1.11e-0325372SM00008
DomainIGc2

LRRC4B UNC5D UNC5B UNC5C

1.16e-03235374SM00408
DomainIg_sub2

LRRC4B UNC5D UNC5B UNC5C

1.16e-03235374IPR003598
DomainK_chnl_volt-dep_Kv

KCNS3 KCNV2

1.30e-0327372IPR003968
DomainIG

LRRC4B SEMA3C UNC5D UNC5B UNC5C

1.37e-03421375SM00409
DomainIg_sub

LRRC4B SEMA3C UNC5D UNC5B UNC5C

1.37e-03421375IPR003599
DomainHRM

ADGRB3 VIPR2

1.40e-0328372PF02793
DomainIon_trans_dom

KCNS3 TRPV1 KCNV2

1.48e-03114373IPR005821
DomainIon_trans

KCNS3 TRPV1 KCNV2

1.48e-03114373PF00520
DomainPSI

SEMA5A SEMA5B

1.82e-0332372PF01437
DomainPlexin_repeat

SEMA5A SEMA5B

1.82e-0332372IPR002165
DomainVG_K_chnl

KCNS3 KCNV2

1.94e-0333372IPR028325
DomainGPCR_2_secretin-like_CS

ADGRB3 VIPR2

2.06e-0334372IPR017983
DomainVWFC_1

THBS2 SSPOP

2.31e-0336372PS01208
DomainVWC

THBS2 SSPOP

2.57e-0338372SM00214
DomainVWFC_2

THBS2 SSPOP

2.57e-0338372PS50184
DomainIG_LIKE

LRRC4B SEMA3C UNC5D UNC5B UNC5C

2.68e-03491375PS50835
DomainG_PROTEIN_RECEP_F2_1

ADGRB3 VIPR2

2.84e-0340372PS00649
DomainGPCR_2_extracellular_dom

ADGRB3 VIPR2

2.84e-0340372IPR001879
DomainG_PROTEIN_RECEP_F2_3

ADGRB3 VIPR2

2.84e-0340372PS50227
DomainAAA+_ATPase

ABCC1 ABCG5 DNAH11

2.88e-03144373IPR003593
DomainAAA

ABCC1 ABCG5 DNAH11

2.88e-03144373SM00382
DomainVWF_dom

THBS2 SSPOP

3.13e-0342372IPR001007
DomainABC_tran

ABCC1 ABCG5

4.07e-0348372PF00005
DomainABC_TRANSPORTER_2

ABCC1 ABCG5

4.07e-0348372PS50893
Domain-

SEMA5A SEMA3C IFT122 SEMA5B

4.12e-033333742.130.10.10
DomainWD40/YVTN_repeat-like_dom

SEMA5A SEMA3C IFT122 SEMA5B

4.21e-03335374IPR015943
DomainABC_TRANSPORTER_1

ABCC1 ABCG5

4.24e-0349372PS00211
DomainG_PROTEIN_RECEP_F2_2

ADGRB3 VIPR2

4.41e-0350372PS00650
Domain7tm_2

ADGRB3 VIPR2

4.41e-0350372PF00002
DomainABC_transporter-like

ABCC1 ABCG5

4.41e-0350372IPR003439
DomainBTB_2

KCNS3 KCNV2

4.94e-0353372PF02214
DomainT1-type_BTB

KCNS3 KCNV2

4.94e-0353372IPR003131
DomainChannel_four-helix_dom

KCNS3 KCNV2

5.69e-0357372IPR027359
Domain-

KCNS3 KCNV2

5.69e-03573721.20.120.350
DomainGPCR_2_secretin-like

ADGRB3 VIPR2

6.29e-0360372IPR000832
DomainGPCR_2-like

ADGRB3 VIPR2

6.29e-0360372IPR017981
DomainG_PROTEIN_RECEP_F2_4

ADGRB3 VIPR2

6.49e-0361372PS50261
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS18 SEMA5A THBS2 THSD1 ADAMTSL5 SEMA5B SSPOP

5.53e-1239367M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS18 SEMA5A THBS2 THSD1 ADAMTSL5 SEMA5B SSPOP

5.53e-1239367MM15165
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS18 SEMA5A THBS2 THSD1 ADAMTSL5 SEMA5B SSPOP

3.31e-1068367M27303
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS18 SEMA5A THBS2 THSD1 ADAMTSL5 SEMA5B SSPOP

9.44e-09109367MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS18 SEMA5A THBS2 THSD1 ADAMTSL5 SEMA5B SSPOP

1.07e-08111367M27416
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS18 SEMA5A THBS2 THSD1 ADAMTSL5 SEMA5B SSPOP

6.23e-08143367M27275
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS18 SEMA5A THBS2 THSD1 LCT ADAMTSL5 SEMA5B SSPOP

1.72e-07250368M27554
PathwayKEGG_AXON_GUIDANCE

SEMA5A SEMA3C SEMA5B UNC5D UNC5B UNC5C

8.13e-07129366M5539
PathwayREACTOME_NETRIN_MEDIATED_REPULSION_SIGNALS

UNC5D UNC5B UNC5C

8.49e-078363M27328
PathwayREACTOME_NETRIN_1_SIGNALING

UNC5D UNC5B UNC5C

1.89e-0444363M875
PathwayREACTOME_OTHER_SEMAPHORIN_INTERACTIONS

CD72 SEMA5A

5.66e-0414362MM15047
PathwayREACTOME_OTHER_SEMAPHORIN_INTERACTIONS

CD72 SEMA5A

1.06e-0319362M10959
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADGRB3 ADAMTS18 SEMA5A THBS2 ADAMTSL5 SEMA5B SSPOP

2.87e-127540720637190
Pubmed

An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.

SEMA5A SEMA3C SEMA5B UNC5D UNC5B UNC5C

3.06e-115240626633812
Pubmed

A novel class of murine semaphorins with homology to thrombospondin is differentially expressed during early embryogenesis.

SEMA5A SEMA3C SEMA5B

1.41e-0854038817451
Pubmed

Cloning of three mouse Unc5 genes and their expression patterns at mid-gestation.

UNC5D UNC5B UNC5C

4.92e-08740312351186
Pubmed

Peri-pubertal emergence of UNC-5 homologue expression by dopamine neurons in rodents.

UNC5D UNC5B UNC5C

4.92e-08740320628609
Pubmed

Invariant Sema5A inhibition serves an ensheathing function during optic nerve development.

SEMA5A SEMA3C SEMA5B

7.86e-08840312506007
Pubmed

The sensory innervation of the mouse spinal cord may be patterned by differential expression of and differential responsiveness to semaphorins.

SEMA5A SEMA3C SEMA5B

1.18e-0794038812066
Pubmed

Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain.

UNC5D UNC5B UNC5C

1.18e-07940323457482
Pubmed

Novel role for Netrins in regulating epithelial behavior during lung branching morphogenesis.

UNC5D UNC5B UNC5C

2.31e-071140315186747
Pubmed

Analysis of Netrin 1 receptors during inner ear development.

UNC5D UNC5B UNC5C

2.31e-071140317616930
Pubmed

Widespread Differential Expression of Coding Region and 3' UTR Sequences in Neurons and Other Tissues.

UNC5D UNC5B UNC5C

3.08e-071240326687222
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

SEMA5A SEMA3C SEMA5B UNC5D UNC5B

3.42e-0712640516284245
Pubmed

KDM5c inhibits multidrug resistance of colon cancer cell line by down-regulating ABCC1.

ABCC1 KDM5C

1.29e-06240230257334
Pubmed

Neurites from trigeminal ganglion explants grown in vitro are repelled or attracted by tooth-related tissues depending on developmental stage.

SEMA5A SEMA3C SEMA5B

1.35e-061940315051154
Pubmed

Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.

UNC5D UNC5B UNC5C

2.14e-062240322726835
Pubmed

Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons.

UNC5D UNC5B UNC5C

2.80e-062440326633881
Pubmed

The association of semaphorins 3C, 5A and 6D with liver fibrosis stage in chronic hepatitis C.

SEMA5A SEMA3C

3.87e-06340230592759
Pubmed

Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers.

UNC5B UNC5C

3.87e-06340226859457
Pubmed

Role of the netrin system of repellent factors on synovial fibroblasts in rheumatoid arthritis and osteoarthritis.

UNC5B UNC5C

3.87e-06340219822088
Pubmed

The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment.

UNC5B UNC5C

3.87e-06340212655055
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

SEMA5A THBS2 THSD1 SEMA5B UNC5C

4.24e-0621040516537572
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

SEMA5A SEMA3C SEMA5B

4.53e-062840318617019
Pubmed

Noggin is required for correct guidance of dorsal root ganglion axons.

SEMA5A SEMA3C SEMA5B

5.04e-062940312435358
Pubmed

Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development.

UNC5D UNC5B UNC5C

5.60e-063040332562661
Pubmed

Expansion of the piriform cortex contributes to corticothalamic pathfinding defects in Gli3 conditional mutants.

SEMA5A SEMA3C SEMA5B

6.19e-063140324014668
Pubmed

A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties.

SEMA5A SEMA3C UNC5D

6.83e-063240324192035
Pubmed

Distinct expression of select and transcriptome-wide isolated 3'UTRs suggests critical roles in development and transition states.

UNC5D UNC5B UNC5C

7.51e-063340333951080
Pubmed

Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate.

SEMA3C UNC5B UNC5C

7.51e-063340318480165
Pubmed

The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase.

UNC5B UNC5C

7.73e-06440215729359
Pubmed

Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion.

UNC5D UNC5B

7.73e-06440226235030
Pubmed

UNC5C is required for spinal accessory motor neuron development.

UNC5B UNC5C

7.73e-06440217543537
Pubmed

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

LIPC ABCG5 DNAH11

8.23e-063440319060911
Pubmed

Rejection of inappropriate synaptic partners in mouse retina mediated by transcellular FLRT2-UNC5 signaling.

UNC5D UNC5C

1.29e-05540237557174
Pubmed

Netrin 1 acts as an attractive or as a repulsive cue for distinct migrating neurons during the development of the cerebellar system.

UNC5B UNC5C

1.29e-05540210704383
Pubmed

Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.

SEMA5A SEMA5B

1.29e-05540225313870
Pubmed

Netrin-1 promotes thalamic axon growth and is required for proper development of the thalamocortical projection.

UNC5B UNC5C

1.93e-05640210908620
Pubmed

Netrin-1 is a chemorepellent for oligodendrocyte precursor cells in the embryonic spinal cord.

UNC5B UNC5C

1.93e-05640212736344
Pubmed

Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension.

SEMA3C SEMA5B

1.93e-0564027748561
Pubmed

TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.

SEMA5A SEMA3C SEMA5B

2.21e-054740335462405
Pubmed

Essential function of oncostatin m in nociceptive neurons of dorsal root ganglia.

TRPV1 OSMR

2.70e-05740214985435
Pubmed

Pax6 is required for the normal development of the forebrain axonal connections.

SEMA5A SEMA3C

2.70e-05740212397112
Pubmed

FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development.

UNC5D UNC5B

2.70e-05740225374360
Pubmed

Floor plate and netrin-1 are involved in the migration and survival of inferior olivary neurons.

UNC5B UNC5C

3.60e-05840210341242
Pubmed

Topography of thalamic projections requires attractive and repulsive functions of Netrin-1 in the ventral telencephalon.

UNC5B UNC5C

3.60e-05840218479186
Pubmed

Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling.

SEMA3C UNC5B UNC5C

4.38e-055940331351040
Pubmed

Inactivation of the Sema5a gene results in embryonic lethality and defective remodeling of the cranial vascular system.

SEMA5A SEMA5B

4.62e-05940215743826
Pubmed

A role for proneural genes in the maturation of cortical progenitor cells.

SEMA3C UNC5D

8.45e-051240216766700
Pubmed

FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons.

UNC5D UNC5B

8.45e-051240221673655
Pubmed

A locus on mouse Chromosome 9 (Adip5) affects the relative weight of the gonadal but not retroperitoneal adipose depot.

LIPC MAN2C1

9.98e-051340217103052
Pubmed

Pax6 exerts regional control of cortical progenitor proliferation via direct repression of Cdk6 and hypophosphorylation of pRb.

SEMA5A SEMA3C

9.98e-051340223622063
Pubmed

Dorsally derived netrin 1 provides an inhibitory cue and elaborates the 'waiting period' for primary sensory axons in the developing spinal cord.

UNC5B UNC5C

1.16e-041440216510500
Pubmed

The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function.

ANKRD11 SEMA3C

1.16e-041440238951500
Pubmed

FLRT2 and FLRT3 Cooperate in Maintaining the Tangential Migratory Streams of Cortical Interneurons during Development.

UNC5D UNC5B

1.34e-041540234301831
Pubmed

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.

ANKRD11 DNAH11

1.73e-041740223502783
Pubmed

Development of the prethalamus is crucial for thalamocortical projection formation and is regulated by Olig2.

SEMA5A UNC5C

1.95e-041840224803655
Pubmed

Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons.

UNC5B UNC5C

2.18e-041940223307742
Pubmed

The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3.

SEMA5B KDM5C

2.42e-042040223637629
Pubmed

Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1.

UNC5B UNC5C

2.67e-042140223312517
Pubmed

Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.

SEMA5A SEMA5B

2.67e-042140221835343
Pubmed

Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity.

SEMA3C SEMA5B

2.67e-042140236240771
Pubmed

CECR2 is involved in spermatogenesis and forms a complex with SNF2H in the testis.

CECR2 UNC5C

2.67e-042140222154806
Pubmed

Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development.

SEMA5A SEMA3C

2.94e-042240236549270
Pubmed

Stromal netrin 1 coordinates renal arteriogenesis and mural cell differentiation.

UNC5B UNC5C

2.94e-042240237823339
Pubmed

Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c.

SEMA3C UNC5D

2.94e-042240226182416
Pubmed

Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney.

UNC5B CAPN6

2.94e-042240229449449
Pubmed

Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease.

SEMA5A UNC5C

2.94e-042240218628988
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

SEMA5A THBS2 LIPC OSMR KCNV2 UNC5C

3.14e-0481440623251661
Pubmed

Netrin 1 directs vascular patterning and maturity in the developing kidney.

UNC5B UNC5C

3.21e-042340237818607
Pubmed

Genomic variants in an inbred mouse model predict mania-like behaviors.

TRPV1 DNAH11

3.21e-042340229768498
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

SEMA5A SEMA3C SEMA5B

3.35e-0411740317145500
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ADGRB3 SMG1 SEMA5B KDM5C CECR2

3.39e-0452940514621295
Pubmed

A semaphorin code defines subpopulations of spinal motor neurons during mouse development.

SEMA5A SEMA3C

3.50e-042440215869472
Pubmed

Ca2+ homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling.

SEMA3C UNC5C

4.12e-042640235927240
Pubmed

Defining the lineage of thermogenic perivascular adipose tissue.

VIPR2 TRPV1

5.13e-042940233846639
Pubmed

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.

LIPC ABCG5

5.50e-043040219936222
Pubmed

Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.

SEMA3C UNC5B

5.87e-043140222076636
Pubmed

Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.

VIPR2 ABCC1 ADAMTSL5

5.89e-0414240319851296
Pubmed

Association of genetic variants with hemorrhagic stroke in Japanese individuals.

VIPR2 ABCC1 ADAMTSL5

6.02e-0414340320198315
Pubmed

Biological, clinical and population relevance of 95 loci for blood lipids.

LIPC ABCG5 DNAH11

6.39e-0414640320686565
Pubmed

GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development.

LCT ABCG5

9.30e-043940224929016
Pubmed

Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.

IFT122 DNAH11

9.79e-044040232317081
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCNS3 KCNV2

9.79e-044040216382104
Pubmed

Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.

LIPC ABCG5

1.03e-034140219878569
InteractionFLRT3 interactions

UNC5D UNC5B UNC5C

1.16e-0523393int:FLRT3
InteractionNTN1 interactions

UNC5D UNC5B UNC5C

1.69e-0526393int:NTN1
InteractionFLRT2 interactions

UNC5D UNC5B UNC5C

2.36e-0529393int:FLRT2
InteractionFLRT1 interactions

UNC5D UNC5B UNC5C

9.60e-0546393int:FLRT1
InteractionPIGA interactions

KCNS3 THBS2 CCDC107

1.16e-0449393int:PIGA
Cytoband2p21

THADA ABCG5

1.31e-03614022p21
Cytoband9p13.3

CD72 CCDC107

1.97e-03754029p13.3
CytobandEnsembl 112 genes in cytogenetic band chr2p21

THADA ABCG5

2.24e-0380402chr2p21
CytobandEnsembl 112 genes in cytogenetic band chr7q36

VIPR2 SSPOP

8.53e-03159402chr7q36
CytobandEnsembl 112 genes in cytogenetic band chr3q21

IFT122 SEMA5B

8.63e-03160402chr3q21
CytobandEnsembl 112 genes in cytogenetic band chr9p13

CD72 CCDC107

1.01e-02174402chr9p13
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA5A SEMA3C SEMA5B

4.15e-0620293736
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

LRRC4B SEMA3C UNC5D UNC5B UNC5C

5.26e-06161295593
GeneFamilyPotassium voltage-gated channels

KCNS3 KCNV2

1.87e-0340292274
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

ADAMTS18 VIPR2 KCNS3 SEMA3C OSMR ADAMTSL5 SEMA5B UTRN UNC5B DNAH11

2.75e-0610743910M1941
CoexpressionGSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_UP

THBS2 THADA LIPC OSMR ADAMTSL5

1.15e-05200395M6780
CoexpressionKYNG_DNA_DAMAGE_BY_4NQO

ANKRD11 ABCC1 CYB5A

2.10e-0536393M11361
CoexpressionGSE7509_FCGRIIB_VS_TNFA_IL1B_IL6_PGE_STIM_DC_DN

ANKRD11 KCNS3 ADAMTSL5 UTRN

8.03e-05154394M6824
CoexpressionHEVNER_CORTEX_ROSTRAL_SUBVENTRICULAR_ZONE

SEMA5A SEMA3C

1.18e-0411392MM448
CoexpressionGENTILE_UV_LOW_DOSE_DN

SEMA5A SEMA3C UTRN

1.19e-0464393M4594
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_BRAIN_ENDOTHELIAL

SEMA5A THSD1 UTRN UNC5B CYB5A

1.99e-04365395M39018
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_PERICYTE

SEMA5A KCNS3 LRRC4B SEMA5B

1.99e-04195394M45684
CoexpressionGSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_DN

OSMR THSD1 KCNV2 CAPN6

2.11e-04198394M7916
CoexpressionGSE360_L_MAJOR_VS_T_GONDII_DC_DN

SMG1 THBS2 OSMR ZBED4

2.11e-04198394M5208
CoexpressionGSE3982_MAST_CELL_VS_NKCELL_DN

ANKRD11 CD72 UNC5B UNC5C

2.15e-04199394M5452
CoexpressionGSE17721_12H_VS_24H_POLYIC_BMDC_DN

CD72 UTRN CYB5A CCDC107

2.20e-04200394M4102
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#2

ADGRB3 LRRC4B THBS2 SEMA5B

3.36e-05100394Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_500_K2
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000

ADAMTS18 SEMA5A LRRC4B SEMA3C LIPC SEMA5B CECR2 UNC5C CAPN6

5.82e-05986399PCBC_EB_fibroblast_1000
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A LRRC4B UTRN UNC5C DNAH11

1.17e-081774064943d040eee0f9dceaddc7498171281d170e271f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A LRRC4B UTRN UNC5C DNAH11

1.17e-081774063f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ADGRB3 VIPR2 SEMA5A THBS2 SEMA5B UNC5C

1.57e-08186406cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

ADGRB3 VIPR2 SEMA5A THBS2 SEMA5B UNC5C

1.84e-0819140678c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA5A KCNS3 SEMA3C UNC5D UNC5C

7.58e-08120405a4e3f9a83bc52ccc75bcd64b1be4e2c5441f6d1a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA5A KCNS3 SEMA3C UNC5D UNC5C

3.49e-07163405bba830a302919c8b33f914a8839877fc21dd28a0
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

ADGRB3 SEMA5A SEMA5B UTRN UNC5C

6.01e-071824052075efeae633550fb2eb026d0dfd741c8252482e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 VIPR2 SEMA5A LRRC4B UNC5C

6.18e-07183405667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA5A LRRC4B SEMA5B UNC5D DNAH11

6.69e-071864050c477016c1b539b3086a8066c3c6443f08c222a3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A LRRC4B UNC5C DNAH11

6.87e-07187405530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A LRRC4B UNC5C DNAH11

6.87e-07187405ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 SEMA5A THBS2 OSMR UNC5C

7.63e-07191405b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A LRRC4B UNC5C DNAH11

7.83e-0719240524e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SEMA5A THBS2 OSMR UNC5B UNC5C

8.89e-071974052ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SEMA5A THBS2 OSMR UNC5B UNC5C

9.34e-07199405d65ee89d5c7e8ed693d58e6a6de09565840e11c5
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SEMA5A KCNS3 LRRC4B SEMA3C SEMA5B

9.34e-07199405aacd3ffa40a6e6f435aa9be5b959d88812eb69d4
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SEMA5A THBS2 OSMR UNC5B UNC5C

9.34e-07199405bf138cc692df727e087d140c014149ee5da00d9d
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SEMA5A LRRC4B SEMA3C THBS2 CAPN6

9.57e-07200405747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SEMA5A THBS2 OSMR UNC5B UNC5C

9.57e-072004053c898e81444b001835c3f1bbc68183078701b135
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SEMA5A THBS2 OSMR UNC5B UNC5C

9.57e-072004053eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SEMA5A LRRC4B SEMA3C THBS2 CAPN6

9.57e-07200405de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA5A KCNS3 SEMA3C UNC5C

3.69e-061174040602bbad908cb28c5093b74d717da5f2af577943
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Vipr2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

VIPR2 KCNS3 ADAMTSL5 UNC5B

3.95e-061194046425425b2e622c97b6c74c530ccbfe394d3b202d
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

LRRC4B ADAMTSL5 SEMA5B UNC5C

1.21e-051584048d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA5A KCNS3 SEMA3C UNC5C

1.24e-051594040dccc4275b9b4f8554dd556da7218e130bff8fd1
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA5A KCNS3 SEMA3C UNC5C

1.37e-051634048d17f44faf0549fe71a9a45f811f50d767275414
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA5A KCNS3 SEMA3C UNC5C

1.40e-0516440408819970174a3eb4eee8e1e675075828665b845e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 LRRC4B UNC5B UNC5C

1.40e-05164404f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A LRRC4B UNC5C

1.44e-05165404cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A LRRC4B UNC5C

1.44e-051654044f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IFT122 UNC5D UNC5C DNAH11

1.54e-051684049a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 LRRC4B UNC5B UNC5C

1.69e-05172404553701349444eb366df3c11f54bb093434f153c6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 LRRC4B UNC5B UNC5C

1.69e-0517240408a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

SEMA5A LRRC4B UNC5D UNC5C

1.73e-05173404fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LIPC UTRN UNC5D DNAH11

1.85e-05176404327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITPKC THSD1 UTRN UNC5B

1.89e-05177404227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LIPC UTRN UNC5D DNAH11

1.89e-05177404da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITPKC THSD1 UTRN UNC5B

1.89e-0517740466ffa279147961080c104242a08b176e301d80e3
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITPKC THSD1 UTRN UNC5B

1.89e-051774040cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCell356C-Fibroblasts-Fibroblast-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

SEMA3C TRPV1 THBS2 LIPC

1.94e-05178404a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell356C-Fibroblasts-Fibroblast-E|356C / Donor, Lineage, Cell class and subclass (all cells)

SEMA3C TRPV1 THBS2 LIPC

1.94e-05178404371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS18 SEMA5A OSMR UNC5B

1.94e-05178404e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

ADGRB3 SEMA5A SEMA5B UTRN

2.07e-051814048dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADGRB3 SEMA5A SEMA5B UNC5C

2.07e-0518140433cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA5A LIPC UNC5D DNAH11

2.11e-051824045e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

ADGRB3 SEMA5A SEMA5B UTRN

2.16e-05183404e3835db4795362b0442d5893baf2a78efcc20428
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA5A SEMA3C LCT ADAMTSL5

2.16e-05183404ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEMA5A THBS2 CECR2 DNAH11

2.25e-051854047aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

ADGRB3 SEMA5A SEMA5B UTRN

2.25e-05185404ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEMA5A THBS2 CECR2 DNAH11

2.25e-051854042e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS18 SEMA5A SEMA5B DNAH11

2.30e-051864046568358812f0ca4e0161a1a1b29682fbced35c79
ToppCellCOVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type

ADAMTS18 VIPR2 SEMA3C DNAH11

2.35e-05187404ce05b89860573fe0356102e2998d1ef6d1968034
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LIPC UTRN UNC5D DNAH11

2.40e-0518840463a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADAMTS18 SEMA5A KCNS3 SEMA5B

2.45e-051894049c2492c38f27e4c699b40680652e4c64911cce52
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 SEMA5A LRRC4B UNC5C

2.45e-05189404fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAMTS18 SEMA5A KCNS3 SEMA5B

2.50e-0519040410125091ad648163777b02e9f0d5e8d7f17d44a5
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA5A THBS2 OSMR UNC5C

2.50e-0519040445df8fee00f8949937863159d7aa042e72748d9b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C THBS2 UNC5B UNC5C

2.55e-05191404107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3C THBS2 UNC5B UNC5C

2.55e-05191404bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA5A THBS2 OSMR UNC5C

2.60e-05192404162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

LRRC4B SEMA3C THBS2 CAPN6

2.60e-051924044ed5040594ba2d0639f0990697504ecef872ca70
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C OSMR THSD1 UTRN

2.60e-051924049ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

LRRC4B SEMA3C THBS2 CAPN6

2.60e-05192404d4f5d6653564c2c5d0f5f7c932d89cb1b1412844
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA5A THBS2 OSMR UNC5C

2.60e-05192404ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C OSMR THSD1 UTRN

2.60e-05192404a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C OSMR THSD1 UTRN

2.60e-0519240466defad13bd8e79319741e43ddb056841710b1d7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA5A UNC5D ABCG5 DNAH11

2.66e-05193404ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SEMA5A SEMA3C THBS2 SEMA5B

2.66e-05193404000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SEMA5A OSMR UNC5B UNC5C

2.66e-051934045e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR2 SEMA5A OSMR SEMA5B

2.66e-05193404c5bd0ed6f57459e54d2463318e8d9b1879718e63
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

LRRC4B SEMA3C THBS2 CAPN6

2.66e-051934043d85c28f6ebdcb15e875ad01d52d6c138fbf8525
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNS3 SEMA3C THBS2 LIPC

2.71e-051944047bf6edefd13047e04665dbe34051ef3f481f85a4
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 SEMA5A OSMR UNC5C

2.71e-0519440489b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

VIPR2 THBS2 UTRN UNC5C

2.71e-05194404ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SEMA5A KCNS3 SEMA3C SEMA5B

2.71e-0519440467f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNS3 SEMA3C THBS2 LIPC

2.71e-0519440419e5beae2c1f8bf42cbe618e89810ce7b01a396c
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR2 SEMA5A OSMR SEMA5B

2.71e-05194404c45e9d09b5cd6973de6c3f1713b3bf36fa4bfe57
ToppCell15-Trachea-Mesenchymal|Trachea / Age, Tissue, Lineage and Cell class

SEMA5A LRRC4B THBS2 CAPN6

2.82e-051964047e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCellwk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SEMA5A THBS2 SEMA5B CAPN6

2.82e-05196404eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCellParenchymal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA5A LRRC4B UNC5D UNC5C

2.88e-0519740441dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA5A LRRC4B UNC5D UNC5C

2.88e-05197404f66945f9007d59d4208849c7fd727f8519713fbc
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SEMA5A OSMR UNC5B UNC5C

2.88e-051974042f72fd9a5b6d62c24a95ed2246194ea7458c0f12
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS18 KCNS3 SEMA5B DNAH11

2.88e-05197404fd65a9b41df618ff2a09d76dcf9f1ca3f3bdf52a
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SEMA5A KCNS3 LRRC4B SEMA5B

2.94e-0519840476d46950c11cb4708866db0da54ce00d5c0adab8
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

ADGRB3 SEMA5A THBS2 UNC5C

2.94e-05198404bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADGRB3 SEMA5A THBS2 UNC5B

2.94e-051984046a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SEMA5A SEMA3C SEMA5B CAPN6

3.05e-05200404fee22a6a6c7b93af204b5b56f2c34f1411500e18
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SEMA5A OSMR UNC5B UNC5C

3.05e-05200404ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Interneuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ABCC1 OSMR UNC5B UNC5C

3.05e-05200404a6500d0d2e8bcac92381ab771dbdee66b0e1d48e
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

VIPR2 CD72 UNC5B

4.91e-0579403cc17a013a4a57a99c404b10449ef61ce559631d1
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

VIPR2 CD72 UNC5B

4.91e-057940319fb2bc964589ea40e7b9f0809c641331c93dacd
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KCNS3 LCT UTRN

1.79e-04122403eae9d94f8510ac0f434942451d55c7260977b178
ToppCellPND01-03-samps-Lymphocyte-B_cell-B_cell_1|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CD72 LIPC SSPOP

2.06e-041284035d82247ceda55017628720ed8b6c36ff7cec8437
ToppCellPND01-03-samps-Lymphocyte-B_cell|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CD72 LIPC SSPOP

2.06e-041284037661402dd7cd533c1bfe8d9247cecd88c1be9a5e
ToppCellPND01-03-samps-Lymphocyte|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CD72 LIPC SSPOP

2.06e-04128403d3158825a2178244b57ac5ad2676617fd58d8466
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA5A TRPV1 ADAMTSL5

2.15e-041304030f9d3e6297f48ae14d24ac997d8d3a94f337d4d4
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SEMA5A TRPV1 ADAMTSL5

2.15e-04130403fc68a648161dd314d9ee6612fd039cb12171b8c6
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Gpc3_Slc18a3|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA5A SEMA3C SEMA5B

2.51e-04137403d346086f42d8f04d3fa67fe696834284acdc7080
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Vipr2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

VIPR2 KCNS3 UNC5B

2.68e-0414040372c272f44e5600b3037c1dbf9d3a4669a35588d8
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA5A SEMA3C SEMA5B

2.91e-041444030322fef818a963be00535d5f141f028d43de5c6a
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

ANKRD11 SMG1 UTRN

2.41e-0449273GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
DrugANIT

ABCC1 LIPC LCT CYB5A

5.27e-0669384CID000011080
DrugCefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A

KCNS3 ITPKC TRPV1 MAN2C1 UNC5B

1.83e-051973857186_DN
DrugMethacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; PC3; HT_HG-U133A

VIPR2 KCNS3 MAN2C1 OSMR UNC5B

1.88e-051983854062_DN
Diseasenetrin receptor UNC5B measurement

UNC5B UNC5C

1.02e-054392EFO_0802792
Diseaseurate measurement, bone density

ADGRB3 ANKRD11 VIPR2 KCNS3 UTRN PSMG3-AS1 DNAH11

1.48e-05619397EFO_0003923, EFO_0004531
DiseaseLipid Metabolism, Inborn Errors

LIPC ABCG5

2.54e-056392C0023772
Diseasecleft lip

ADGRB3 SEMA5A KCNS3 THADA LIPC

3.51e-05284395EFO_0003959
DiseaseSubarachnoid Hemorrhage

THSD1 UNC5B

6.09e-059392C0038525
Diseaseprostate specific antigen measurement

ADAMTS18 THADA LIPC DNAH11

1.10e-04188394EFO_0004624
DiseaseHypercholesterolemia, Familial

LIPC ABCG5

2.57e-0418392C0020445
Diseasegamma-glutamylglutamine measurement

ABCC1 UNC5D

3.87e-0422392EFO_0021138
Diseasemultiple myeloma

ANKRD11 UNC5B DNAH11

4.40e-04112393EFO_0001378
DiseaseCoronary heart disease

ABCG5 DNAH11

4.61e-0424392C0010068
DiseaseDyslipidemias

ABCG5 DNAH11

4.61e-0424392C0242339
DiseaseDyslipoproteinemias

ABCG5 DNAH11

4.61e-0424392C0598784
Diseaseskin microbiome measurement

ADGRB3 THADA

1.22e-0339392EFO_0801228
DiseaseHypercholesterolemia

LIPC ABCG5

1.22e-0339392C0020443
Diseasetotal lipids in very small VLDL measurement

LIPC ABCG5

1.63e-0345392EFO_0022156
Diseasecortical surface area measurement

ADAMTS18 SEMA5A KCNS3 SEMA3C THADA UNC5C DNAH11

1.72e-031345397EFO_0010736
DiseasePrimary Ciliary Dyskinesia

IFT122 DNAH11

1.77e-0347392C4551720
Diseaseresponse to trauma exposure

UNC5D DNAH11

2.08e-0351392EFO_0008483
Diseasephospholipids in very small VLDL measurement

LIPC ABCG5

2.08e-0351392EFO_0022300
Diseasefree cholesterol to total lipids in small HDL percentage

LIPC ABCG5

2.08e-0351392EFO_0022285
DiseaseRespiratory Distress Syndrome, Adult

LCT CYB5A

2.42e-0355392C0035222
Diseasevascular endothelial growth factor measurement

SEMA5B KCNV2

2.51e-0356392EFO_0004762

Protein segments in the cluster

PeptideGeneStartEntry
WRTDNWKTISSPAWS

ANKRD11

546

Q6UB99
RETWAWLSRTDTAWP

C19orf48

86

Q6RUI8
GVWEEWSPWSLCSFT

ADGRB3

346

O60242
LCPVDGQWQEWSSWS

ADGRB3

396

O60242
LTAATTWLTWQDDCW

DNAH11

796

Q96DT5
TWSWWTLESESCRSS

CD72

331

P21854
GTWWLLCQTEEEWRQ

CECR2

241

Q9BXF3
QWSAWSKWSECSRTC

ADAMTS18

591

Q8TE60
PNFWSNWSSWEEVSV

OSMR

126

Q99650
WSWSELETTCLWTET

ITPKC

126

Q96DU7
SICWNPSSRWESFWM

IFT122

181

Q9HBG6
LPWDQTPWRVSFSWS

PSMG3-AS1

21

Q96PY0
GSISSSNWWSWVRQP

IGHV4-4

46

A0A075B6R2
TTIDSSSSWWTNWVI

CYB5A

101

P00167
SSSWWTNWVIPAISA

CYB5A

106

P00167
WANVWDTVQTIIPWS

LIPC

426

P11150
VWPQTSSSWIRVVPW

LCT

716

P09848
TSSLTSIPICWWWAT

KCNS3

351

Q9BQ31
GEWTPWVSWTRCSSS

ADAMTSL5

46

Q6ZMM2
WEEPTNWSTETWNLA

CCDC107

226

Q8WV48
NWSTETWNLATSWEV

CCDC107

231

Q8WV48
VRPWWDITSCRQQWT

ABCG5

51

Q9H222
TWWTCWFRVELTIPE

MAN2C1

76

Q9NTJ4
WSGPWSEISEEWQQL

CAPN6

291

Q9Y6Q1
WLSWWLKETVPSNTT

LRRC4B

321

Q9NT99
GSDPLWDWNVTWNTS

ABCC1

11

P33527
WDWNVTWNTSNPDFT

ABCC1

16

P33527
AGWSRVRTWTEDWCN

UTRN

1631

P46939
SSWIDQWHETWVSPL

THADA

516

Q6YHU6
TDKWSPWTWASSVRA

SEMA3C

671

Q99985
DGEWSTWSPWSVCSE

SSPOP

1751

A2VEC9
TEVFGWTPWTSWSSC

SSPOP

2771

A2VEC9
ECAVPEAWTLWSSWS

SSPOP

4251

A2VEC9
EAWTLWSSWSDCPVS

SSPOP

4256

A2VEC9
EECVWSSWSSWTRCS

SSPOP

4366

A2VEC9
VPSTNFTTIPHSWWW

KCNV2

436

Q8TDN2
WSSCTTPDEWWRVTQ

SMG1

2301

Q96Q15
NTQPCPESWSEWSDW

SEMA5A

891

Q13591
WCFRVDEVNWTTWNT

TRPV1

741

Q8NER1
ETWGLWQPWSQCSAT

THSD1

341

Q9NS62
EGWSPWSEWSKCTDD

SEMA5B

966

Q9P283
VDGAWTEWSKWSACS

UNC5B

301

Q8IZJ1
PVDGSWEVWSEWSVC

UNC5D

306

Q6UXZ4
WEVWSEWSVCSPECE

UNC5D

311

Q6UXZ4
CWDTNDHSVPWWVIR

VIPR2

271

P41587
EEGWSPWAEWTQCSV

THBS2

381

P35442
WESSWEEQPDWTLGC

TMIGD3

16

P0DMS9
GGWSTWTEWSVCNSR

UNC5C

261

O95185
KQLECWWEAWVTSTG

ZBED4

786

O75132
NPTSSPLLAWWEWDT

KDM5C

1226

P41229