Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

ERBB3 ABL2

4.50e-03145142GO:0004713
GeneOntologyMolecularFunctionprotein kinase activity

DMPK ERBB3 ABL2

7.67e-03600143GO:0004672
GeneOntologyBiologicalProcessanatomical structure maturation

DCHS1 CACNA1A ABL2 RUNX1

7.45e-05354144GO:0071695
GeneOntologyBiologicalProcessdevelopmental maturation

DCHS1 CACNA1A ABL2 RUNX1

1.71e-04439144GO:0021700
GeneOntologyBiologicalProcessbehavioral response to pain

CACNA1A RUNX1

2.10e-0432142GO:0048266
GeneOntologyBiologicalProcesspositive regulation of interleukin-2 production

ABL2 RUNX1

3.63e-0442142GO:0032743
GeneOntologyBiologicalProcessneuromuscular process

DMPK CACNA1A ABL2

4.27e-04225143GO:0050905
GeneOntologyBiologicalProcessadult walking behavior

CACNA1A ABL2

5.14e-0450142GO:0007628
GeneOntologyBiologicalProcessresponse to pain

CACNA1A RUNX1

5.35e-0451142GO:0048265
GeneOntologyBiologicalProcessendocardial cushion development

DCHS1 ERBB3

6.92e-0458142GO:0003197
GeneOntologyBiologicalProcesscerebellum morphogenesis

CACNA1A ABL2

7.40e-0460142GO:0021587
GeneOntologyBiologicalProcesswalking behavior

CACNA1A ABL2

7.40e-0460142GO:0090659
GeneOntologyBiologicalProcesshindbrain morphogenesis

CACNA1A ABL2

8.42e-0464142GO:0021575
GeneOntologyBiologicalProcesssynapse organization

DMPK CACNA1A ARHGAP22 ABL2

9.25e-04685144GO:0050808
GeneOntologyBiologicalProcessmusculoskeletal movement

DMPK CACNA1A

9.78e-0469142GO:0050881
GeneOntologyBiologicalProcessmulticellular organismal movement

DMPK CACNA1A

1.09e-0373142GO:0050879
GeneOntologyBiologicalProcessregulation of interleukin-2 production

ABL2 RUNX1

1.12e-0374142GO:0032663
GeneOntologyBiologicalProcessneuromuscular process controlling balance

CACNA1A ABL2

1.12e-0374142GO:0050885
GeneOntologyBiologicalProcessinterleukin-2 production

ABL2 RUNX1

1.38e-0382142GO:0032623
GeneOntologyBiologicalProcessregulation of extracellular matrix organization

ABL2 RUNX1

1.44e-0384142GO:1903053
GeneOntologyBiologicalProcessregulation of neuron apoptotic process

HRK CACNA1A ERBB3

1.60e-03355143GO:0043523
GeneOntologyBiologicalProcessnegative regulation of cell adhesion

ERBB3 ABL2 RUNX1

1.87e-03375143GO:0007162
GeneOntologyBiologicalProcesscirculatory system development

DCHS1 ARHGAP22 ERBB3 ABL2 RUNX1

1.95e-031442145GO:0072359
GeneOntologyBiologicalProcessperipheral nervous system development

ERBB3 RUNX1

1.96e-0398142GO:0007422
GeneOntologyBiologicalProcesspositive regulation of type II interferon production

ABL2 RUNX1

2.16e-03103142GO:0032729
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

DCHS1 CACNA1A ARHGAP22 ABL2 RUNX1

2.21e-031483145GO:0048646
GeneOntologyBiologicalProcessneuron apoptotic process

HRK CACNA1A ERBB3

2.46e-03413143GO:0051402
GeneOntologyBiologicalProcessadult locomotory behavior

CACNA1A ABL2

2.73e-03116142GO:0008344
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

DCHS1 EVX1 ABL2 RUNX1

2.85e-03929144GO:0009792
GeneOntologyBiologicalProcessmulticellular organismal response to stress

CACNA1A RUNX1

3.21e-03126142GO:0033555
GeneOntologyBiologicalProcesscell junction organization

DMPK CACNA1A ARHGAP22 ABL2

3.38e-03974144GO:0034330
GeneOntologyBiologicalProcessresponse to retinoic acid

ABL2 RUNX1

3.47e-03131142GO:0032526
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled receptor signaling pathway

NTSR2 ABL2

3.57e-03133142GO:0007200
DomainTyrKc

ERBB3 ABL2

1.93e-0388142SM00219
DomainTyr_kinase_cat_dom

ERBB3 ABL2

1.93e-0388142IPR020635
DomainPROTEIN_KINASE_TYR

ERBB3 ABL2

2.33e-0397142PS00109
DomainTyr_kinase_AS

ERBB3 ABL2

2.33e-0397142IPR008266
DomainPkinase_Tyr

ERBB3 ABL2

4.08e-03129142PF07714
DomainPROTEIN_KINASE_ATP

DMPK ERBB3 ABL2

4.39e-03459143PS00107
DomainSer-Thr/Tyr_kinase_cat_dom

ERBB3 ABL2

4.65e-03138142IPR001245
DomainProt_kinase_dom

DMPK ERBB3 ABL2

5.24e-03489143IPR000719
DomainPROTEIN_KINASE_DOM

DMPK ERBB3 ABL2

5.36e-03493143PS50011
DomainKinase-like_dom

DMPK ERBB3 ABL2

6.97e-03542143IPR011009
Pubmed

Associations of rs2300782 CAMK4, rs2292239 ERBB3 and rs10491034 ARHGAP22 with Diabetic Retinopathy Among Chinese Hui Population.

ARHGAP22 ERBB3

4.51e-07314231976761
Pubmed

Dchs1-Fat4 regulation of polarized cell behaviours during skeletal morphogenesis.

DCHS1 RUNX1

3.16e-06714227145737
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

CACNA1A ARHGAP22 CEP72

1.35e-0511814321078624
Pubmed

The Repeat Expansion Diseases: The dark side of DNA repair.

DMPK CACNA1A

3.79e-052314226002199
Pubmed

Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA.

EVX1 RUNX1

7.89e-053314230917309
Pubmed

Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia.

EVX1 RUNX1

8.89e-053514238025786
Pubmed

Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression.

EVX1 RUNX1

2.05e-045314227210758
Pubmed

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.

ERBB3 ABL2 RUNX1

4.02e-0437114325241761
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|343B / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP22 CEP72 ABL2

1.42e-0515514384221a285277292f7225eb69508c887541abeed1
ToppCellP28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DMPK CACNA1A ARHGAP22

1.81e-051681438c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCellfacs-Heart-RA-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMPK ARHGAP22 RUNX1

1.97e-051731435058cb5e3f2d57dbe947e1b113eb2bef7bf6dd7d
ToppCellfacs-Heart-RA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMPK ARHGAP22 RUNX1

1.97e-051731434fa5f502fa3ff8f888e279f68a0dafd91b37f26f
ToppCellfacs-Heart-RA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMPK ARHGAP22 RUNX1

1.97e-05173143ea406b47ff3ead992bc06f6b1707c76eee574782
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCHS1 CACNA1A ARHGAP22

2.01e-051741437be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ERBB3 ABL2 RUNX1

2.08e-051761431e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCellSigmoid-Dendritic_cell-cDC1|Sigmoid / Region, Cell class and subclass

ARHGAP22 SLC45A1 RUNX1

3.04e-052001433523ec986e8c9e176e08836c974b1de8b56d8b16
ToppCellSigmoid-(5)_Dendritic_cell-(51)_cDC1|Sigmoid / shred on region, Cell_type, and subtype

ARHGAP22 SLC45A1 RUNX1

3.04e-052001434ce0a2238c90622e41fd86ac4b7d82adf4af2c3b
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ARHGAP22 CCDC116

2.27e-04721427877184d5c9dd6d96476d71e7504e58c0b4d0f26
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ERBB3 RUNX1

3.24e-048614279c4326df78f0a5b3ef13b2fb4e5074934536e35
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CEP72 EVX1

3.55e-04901423817a5b0235e632d976ea565175bdbebbd959bf0
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CEP72 EVX1

3.55e-0490142a528f5dcee1a356dea89ff2588d2e0f276f2d5fc
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P1-P1_1|Thalamus / BrainAtlas - Mouse McCarroll V32

CEP72 ERBB3

5.48e-0411214267b4d2ecc437398c985e6543b82bb593cb164f7f
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1-P1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

CEP72 ERBB3

6.18e-041191420dd72dbded7ade911612d20e0c6e3f40e85fc890
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CEP72 ERBB3

6.18e-041191420c9aff5442a1b1e51e142d6527d5a48211d94335
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Hippocampus / BrainAtlas - Mouse McCarroll V32

CEP72 ERBB3

6.18e-041191427367b6e4906d234ca864075443efe420ee407421
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_B3-5|TCGA-Thymus / Sample_Type by Project: Shred V9

CEP72 EVX1

6.29e-041201429d4e630e1d3b9adf94a1884071bfe46edaa3f0c1
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Car10|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NTSR2 EVX1

6.93e-0412614261e599678680e5aa86291c2b347b2995014591ea
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rxfp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HRK ARHGAP22

7.48e-0413114281efe8b0ca4377e557a42ddb12aecaf3f46b15bf
ToppCellfacs-Heart-RV-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC116 SLC45A1

7.83e-041341420c63c8b3c748d29c59fcb27d03276ba4f6a0d6b2
ToppCellfacs-Heart-RV-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC116 SLC45A1

7.83e-04134142d101e16cb87ff72c81324406fe7e3d70ed8f45df
ToppCellCOVID-19_Moderate-B_cell|World / disease group, cell group and cell class

CACNA1A ERBB3

8.42e-04139142b93e1da87d44e55d75e8cc1b87c2970645679c01
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HRK ARHGAP22

8.66e-041411425ef3166c5271aa90fd0633016edfe2c74b835319
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature_2|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DMPK SLC45A1

8.90e-04143142abe6ec0f6956b87f394d537926eb2427fcfad93f
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DCHS1 ABL2

9.03e-041441425e948d4cb913ccd8f82262a1b4d20967aadab3ab
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ERBB3 SLC45A1

9.40e-04147142aba44c7057096483c4293a7ebcf8ccc8baed0231
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-3|TCGA-Stomach / Sample_Type by Project: Shred V9

DCHS1 ARHGAP22

9.53e-04148142c95a732163050cfb5d604c2a4c9eb1afa9f19a95
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CEP72 ABL2

9.79e-04150142744050a1b665c6989f37141348af3df7579a73c9
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-STAT1+_Naive_B|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMPK HRK

1.00e-03152142dd728aa3ffdb2c415730a62678f69cf0e8af09df
ToppCellP15-Epithelial-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ERBB3 SLC45A1

1.00e-0315214200d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTSR2 ERBB3

1.02e-031531420ef7c45cdd854c79e527006034029767f8e108b2
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CEP72 ABL2

1.03e-03154142874b1220337276489a89fcc9a39bc81ba6b68baf
ToppCellBAL-Control-cDC_12|Control / Compartment, Disease Groups and Clusters

DMPK CACNA1A

1.03e-031541420121d08cc527aed9b3e11ff62bb9012916f5c56b
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1A ERBB3

1.04e-0315514277fdae85d36efb776db977eb424b32487ef222e4
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

DCHS1 ABL2

1.04e-03155142c4dc0fa1d0e657753a56939eb4829fb60382c17f
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

HRK CEP72

1.04e-031551427aba8ef53c9170ad8ed955c904c8991097ab1e32
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

HRK CCDC116

1.06e-03156142b093dbba6662e4fffc8aa577587b77f64ac44b56
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A CCDC116

1.06e-03156142d34f386985dd17293b1e320d732ab11b46be76ce
ToppCelldroplet-Heart-nan-24m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCHS1 CACNA1A

1.10e-031591427ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DMPK CACNA1A

1.13e-031611421d446f5ba57d84949823a35cbedaee8f448fe40f
ToppCelldroplet-Fat-Mat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.13e-031611428c62ae3fcf304db0f71633e328ceba81a70f03c4
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DMPK CACNA1A

1.13e-031611421670108afc0af90861eb80a84e59995571c0da1b
ToppCellnormal-na-Lymphocytic_B-B_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

HRK SLC45A1

1.14e-03162142ae292318d339305932457bb0e91430594f7a3dfa
ToppCelldroplet-Kidney-nan-21m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.17e-03164142d4cdcd61e8c28b3fb912cef8837cc1a49678a729
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A ERBB3

1.17e-03164142d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-mature_NK_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.17e-0316414222f37c39fdce2cf6dc72c6db619537d4b0234839
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMPK CACNA1A

1.17e-03164142b895674ed2df87db8fbfb30b7e31620945588491
ToppCelldroplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 CEP72

1.17e-0316414278de403446fe0eb375c82ff1832cc5fbb8e20afa
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC116 SLC45A1

1.18e-031651420edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Pancreas-Endocrine-3m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.18e-031651424d51eb992670bce164eea29b540877b4d567953c
ToppCellfacs-Pancreas-Endocrine-3m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.18e-031651422e9e703c3f89784a47ed40f799d2aa86eba6cc9a
ToppCell3'_v3-blood-Lymphocytic_B_plasma-Plasma_cells|blood / Manually curated celltypes from each tissue

HRK ZC2HC1B

1.18e-031651421c0c24fe252b761cf879b83562e23c02f0b6489f
ToppCellfacs-Pancreas-Endocrine-3m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.18e-031651428715ea74d02e9b7cd05fa1b4896b353078544678
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP22 CEP72

1.18e-03165142c39f0479955c4e23921f7a450d3bc251a002200f
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC116 SLC45A1

1.18e-03165142fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.20e-03166142d80c2522cf314d56730d60f160b1247933443378
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 ERBB3

1.20e-0316614211b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 ERBB3

1.20e-03166142fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.20e-03166142f2593e2f1043a8cedaa677a73e6b28393991b910
ToppCellfacs-Marrow-KLS-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 SLC45A1

1.21e-03167142d15168f46c1599d9fc68a05a7b822c4b439f2987
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.21e-03167142991a93e1075d562b7391f0689b2f62c1351d48d1
ToppCellfacs-Kidney-nan-3m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.21e-03167142934905aeaafbc215ec8f6a7903498b0e258b9220
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HRK ERBB3

1.21e-0316714217c653b46507c8bb85da95836ae72a6015336142
ToppCellfacs-Marrow-KLS-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 SLC45A1

1.21e-031671422812353ff66e76f10bd327ceb0e6b009502a5258
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP22 ERBB3

1.21e-031671429f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP22 ERBB3

1.21e-03167142bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A RUNX1

1.21e-03167142f5bffa77061baec0ba87bd688a047595f32534db
ToppCellfacs-Kidney-nan-3m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.21e-03167142f22d1471c785b30d096ec5cdc68974e850ed7de0
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

DCHS1 ERBB3

1.22e-031681426501495b7ad252af330b18011696c43031541018
ToppCellControl-NK|Control / Disease group and Cell class

ARHGAP22 ABL2

1.22e-03168142683d389c8a1e791bfc773e63148115a21a6566db
ToppCellInt-URO-Lymphocyte-B-B_intermediate|Int-URO / Disease, Lineage and Cell Type

HRK CACNA1A

1.22e-031681425b3fb1fc8fea810c6d4e6feb42c24fb57e8066de
ToppCelldroplet-Lung-nan-18m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 CCDC116

1.24e-03169142149a4f83da15bdeb170e980fb5b5b1af89ae07a6
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP22 CCDC116

1.25e-03170142bf589c4297ccc90e5f51e3d0fcc229548af4fcef
ToppCelldroplet-Thymus-nan-3m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMPK ARHGAP22

1.27e-03171142508b41e3ad2638f9dd546d251b13ff60fc8c3207
ToppCellfacs-Heart-RA-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.27e-03171142467f53033f172905e653d85aaa6751a00e5d9e10
ToppCellInfluenza_Severe-B_intermediate|World / Disease group and Cell class

CACNA1A ERBB3

1.27e-031711424d33e1dc1efc423dbdd5f4cca6d6440a68add8d0
ToppCelldroplet-Thymus-nan-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMPK ARHGAP22

1.27e-0317114225493a4a7b636920e2cfd984542cc500709c9dcf
ToppCellfacs-Heart-RA-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.27e-0317114215fedb078d93ac4b7fd2945870b50a718f665487
ToppCellmild-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ERBB3 RUNX1

1.27e-031711425c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMPK ABL2

1.28e-03172142574ebdf36e45222bcd907cd2c2ee7ff50ed4573a
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMPK ABL2

1.28e-031721421627fa7035b0e0bbc82a1c0f000d8231254c680a
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 RUNX1

1.28e-03172142cabe7b4131d72da87d3caacd8cced3a4f2cbef53
ToppCell3'_v3-blood-Lymphocytic_B-Naive_B_cells|blood / Manually curated celltypes from each tissue

HRK ZC2HC1B

1.28e-03172142f16f90d17feac1ee52fd513907b28456865fd31d
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGAP22 ERBB3

1.30e-0317314245808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGAP22 ERBB3

1.30e-031731427fa9dbcb258c3ab974490063951620e2def03db1
ToppCellCOVID-19-kidney-REN+Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A EVX1

1.31e-031741428393f0b43c767839c1630bcb952d62b42efc788d
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A SLC45A1

1.31e-03174142a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1A ARHGAP22

1.33e-031751421b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1A ARHGAP22

1.33e-03175142cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1A ARHGAP22

1.33e-0317514296219e58dcb327fd27190be78193e7a0d611e62b
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMPK ABL2

1.34e-031761428e89471f838ea81235256cc2470f1c12c9b75f8a
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-progenitor-Germ|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HRK EVX1

1.34e-03176142eea554ea75580f8dd5fefb57e7f33441ab86b884
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HRK EVX1

1.34e-03176142d5cee483d2a60f82fdc67ad447b589d022fe8c97
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMPK ARHGAP22

1.36e-0317714226bad614560609d318bfc9c235a698bca4e1c22c
ToppCellILEUM-inflamed-(9)_Enteric_neurons|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DCHS1 ERBB3

1.37e-03178142d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMPK SLC45A1

1.37e-03178142d3a75a8082e70543b84c35d53fe77625300d19fa
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMPK SLC45A1

1.37e-03178142b2cda1df801b1a1a41e3dd2808baef37765cd804
ToppCellILEUM-inflamed-(9)_Neuro_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DCHS1 ERBB3

1.37e-03178142611504b0a9e6318b18fba83787b03f9245c82252
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A EVX1

1.39e-03179142d70791d2a0db35a6b013fa7ed2f9f39364581eff
DrugFluorometholone [426-13-1]; Up 200; 10.6uM; PC3; HT_HG-U133A

DMPK HRK ARHGAP22 RUNX1

4.98e-061961445771_UP
DrugDichlorodiphenyl Dichloroethylene

HRK CACNA1A ERBB3 RUNX1

2.74e-05302144ctd:D003633
Drug3HPP

DMPK CACNA1A

4.75e-0517142CID000000091
DrugCortisporin

HRK CACNA1A EVX1

1.58e-04177143CID000004454
DrugC0107

DMPK CACNA1A

1.83e-0433142CID000018639
DrugEtofylline [519-37-9]; Up 200; 17.8uM; PC3; HT_HG-U133A

ARHGAP22 ABL2 RUNX1

2.04e-041931432093_UP
DrugBretylium tosylate [61-75-6]; Up 200; 9.6uM; MCF7; HT_HG-U133A

DMPK ABL2 RUNX1

2.04e-041931435020_UP
DrugHydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A

DMPK CACNA1A RUNX1

2.07e-041941432311_UP
DrugHaloperidol [52-86-8]; Up 200; 10.6uM; PC3; HT_HG-U133A

DMPK CACNA1A RUNX1

2.07e-041941434678_UP
DrugZalcitabine [7481-89-2]; Up 200; 19uM; MCF7; HT_HG-U133A

DMPK HRK RUNX1

2.07e-041941437352_UP
DrugTrichlormethiazide [133-67-5]; Down 200; 10.6uM; PC3; HT_HG-U133A

ARHGAP22 ABL2 RUNX1

2.10e-041951434198_DN
DrugGemfibrozil [25812-30-0]; Up 200; 16uM; PC3; HT_HG-U133A

HRK CEP72 RUNX1

2.10e-041951432113_UP
DrugSulfamerazine [127-79-7]; Down 200; 15.2uM; PC3; HT_HG-U133A

DMPK CACNA1A RUNX1

2.10e-041951433718_DN
DrugTrichlorfon [52-68-6]; Up 200; 15.6uM; MCF7; HT_HG-U133A

DMPK NTSR2 RUNX1

2.13e-041961435989_UP
DrugFluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A

DMPK HRK RUNX1

2.13e-041961433314_UP
Drug3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; PC3; HT_HG-U133A

CACNA1A ARHGAP22 RUNX1

2.13e-041961433742_DN
DrugEtilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; PC3; HT_HG-U133A

DMPK ABL2 RUNX1

2.13e-041961434590_DN
Drugestradiol, USP; Down 200; 0.01uM; PC3; HT_HG-U133A

DMPK HRK RUNX1

2.13e-041961434465_DN
DrugPargyline hydrochloride [306-07-0]; Up 200; 20.4uM; PC3; HT_HG-U133A

HRK ARHGAP22 RUNX1

2.13e-041961432102_UP
DrugNicardipine hydrochloride [54527-84-3]; Up 200; 7.8uM; MCF7; HT_HG-U133A

CACNA1A ABL2 RUNX1

2.13e-041961435397_UP
DrugFoliosidine [2520-38-9]; Down 200; 13uM; PC3; HT_HG-U133A

CACNA1A ABL2 RUNX1

2.13e-041961433739_DN
DrugProchlorperazine dimaleate [84-02-6]; Up 200; 6.6uM; PC3; HT_HG-U133A

DMPK ABL2 RUNX1

2.16e-041971436664_UP
DrugMetronidazole [443-48-1]; Down 200; 23.4uM; PC3; HT_HG-U133A

DMPK CACNA1A RUNX1

2.20e-041981434023_DN
DrugHarmane hydrochloride [21655-84-5]; Down 200; 18.2uM; PC3; HT_HG-U133A

DMPK CACNA1A RUNX1

2.20e-041981434584_DN
DrugCarbenoxolone disodium salt [7421-40-1]; Down 200; 6.6uM; PC3; HT_HG-U133A

CACNA1A ARHGAP22 RUNX1

2.20e-041981434093_DN
DrugCiprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A

HRK CACNA1A RUNX1

2.20e-041981431522_UP
DrugGabapentin [60142-96-3]; Up 200; 23.4uM; PC3; HT_HG-U133A

CACNA1A ABL2 RUNX1

2.20e-041981435875_UP
DrugMelatonin [73-31-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A

DMPK HRK ABL2

2.20e-041981435393_UP
DrugOxybenzone [131-57-7]; Up 200; 17.6uM; MCF7; HT_HG-U133A

ARHGAP22 ABL2 RUNX1

2.20e-041981435410_UP
DrugDelsoline [509-18-2]; Up 200; 8.6uM; PC3; HT_HG-U133A

HRK ABL2 RUNX1

2.20e-041981435858_UP
DrugPhthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A

DMPK CACNA1A RUNX1

2.20e-041981435614_UP
DrugPirlindole mesylate [60762-57-4]; Down 200; 12.4uM; HL60; HT_HG-U133A

CACNA1A CEP72 RUNX1

2.23e-041991433140_DN
DrugIodipamide [606-17-7]; Up 200; 3.6uM; PC3; HT_HG-U133A

ARHGAP22 ERBB3 RUNX1

2.23e-041991435085_UP
DrugMonobenzone [103-16-2]; Up 200; 20uM; PC3; HT_HG-U133A

HRK CACNA1A RUNX1

2.23e-041991436713_UP
DrugCephalothin sodium salt [58-71-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A

HRK ABL2 RUNX1

2.23e-041991436079_DN
Drug(cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; PC3; HT_HG-U133A

DMPK DCHS1 RUNX1

2.23e-041991433806_UP
DrugICI 182,780; Up 200; 0.01uM; PC3; HT_HG-U133A

HRK ABL2 RUNX1

2.26e-042001431238_UP
DrugLysergol [602-85-7]; Up 200; 15.8uM; MCF7; HT_HG-U133A

DMPK CEP72 RUNX1

2.26e-042001434966_UP
Drug3,4-diaminopyridine

DMPK CACNA1A

2.44e-0438142CID000005918
DrugAC1Q6T4Q

HRK ERBB3

3.42e-0445142CID000000516
Drugvorinostat

CACNA1A ERBB3 RUNX1

8.45e-04314143CID000005311
DrugN5,N10-methylene tetrahydrofolic acid

CACNA1A RUNX1

9.50e-0475142CID000000884
DrugNSC 714187

ERBB3 RUNX1

1.22e-0385142CID005288693
Diseasecolorectal adenocarcinoma (is_marker_for)

ERBB3 RUNX1

7.29e-0527142DOID:0050861 (is_marker_for)
Diseasepsoriasis

ERBB3 SLC45A1 RUNX1

2.64e-04273143EFO_0000676
DiseaseAlzheimer disease, age at onset

DCHS1 HRK ERBB3

5.15e-04343143EFO_0004847, MONDO_0004975
Diseaseage of onset of asthma

ERBB3 RUNX1

6.31e-0479142OBA_2001001
Diseaseleft ventricular structural measurement

EVX1 RUNX1

7.82e-0488142EFO_0008205
DiseaseInhalant adrenergic use measurement

ERBB3 RUNX1

9.29e-0496142EFO_0009941
Diseaseadult onset asthma

ERBB3 RUNX1

1.40e-03118142EFO_1002011
Diseasebrain volume measurement

HRK CACNA1A ERBB3

2.52e-03595143EFO_0006930
Diseaselung non-small cell carcinoma (is_marker_for)

ERBB3 RUNX1

2.84e-03169142DOID:3908 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
RHMSPPLGLGKKCPA

CACNA1A

1856

O00555
ERCPRPVSLHPMPRG

ERBB3

1076

P21860
PLVPEMRPACKPGRV

CCDC116

31

Q8IYX3
MRPACKPGRVPHPPS

CCDC116

36

Q8IYX3
KCAPPPPPVMRLLQH

ABL2

981

P42684
KMVPRGCLSPRAVPP

EVX1

41

P49640
MVPGPLPAPGKCRKR

CEP72

321

Q9P209
CPGMKSPRPHLLLPL

DCHS1

11

Q96JQ0
LCGEHHPMKRLPPKP

NTSR2

376

O95665
CPLVGPGPMHRRHLL

DMPK

561

Q09013
CRLHPQGRPPALPTM

SLC45A1

21

Q9Y2W3
MCPCPLHRGRGPPAV

HRK

1

O00198
MVGGERSPPRILPPC

RUNX1

391

Q01196
PGRMPCPHRLGPVLK

ARHGAP22

26

Q7Z5H3
CMLAIKEGRPLPPPP

ZC2HC1B

96

Q5TFG8