Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL4A2 COL4A4 COL7A1 LAMA4 MATN4 SSPOP HMCN2 PODN PCOLCE2 MUC5AC FBN3	7.83e-08	188	138	11	GO:0005201
GeneOntologyCellularComponent	extracellular matrix	COL4A2 COL4A4 COL7A1 ADAMTS1 VASN LAMA4 MATN4 ADAMTS13 SSPOP SSC5D SFTPA2 HMCN2 ADAMTS7 PODN SFTPA1 PCOLCE2 MUC5AC FBN3	2.67e-07	656	136	18	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL4A2 COL4A4 COL7A1 ADAMTS1 VASN LAMA4 MATN4 ADAMTS13 SSPOP SSC5D SFTPA2 HMCN2 ADAMTS7 PODN SFTPA1 PCOLCE2 MUC5AC FBN3	2.79e-07	658	136	18	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL4A2 COL4A4 COL7A1 ADAMTS1 LAMA4 MATN4 SSPOP SSC5D SFTPA2 HMCN2 PODN SFTPA1 PCOLCE2	4.36e-05	530	136	13	GO:0062023
GeneOntologyCellularComponent	basement membrane	COL4A2 COL4A4 COL7A1 ADAMTS1 LAMA4 HMCN2	1.48e-04	122	136	6	GO:0005604
GeneOntologyCellularComponent	collagen trimer	COL4A2 COL4A4 COL7A1 SFTPA2 SFTPA1	2.75e-04	88	136	5	GO:0005581
GeneOntologyCellularComponent	complex of collagen trimers	COL4A2 COL4A4 COL7A1	3.29e-04	21	136	3	GO:0098644
GeneOntologyCellularComponent	collagen type IV trimer	COL4A2 COL4A4	6.20e-04	6	136	2	GO:0005587
GeneOntologyCellularComponent	basement membrane collagen trimer	COL4A2 COL4A4	1.15e-03	8	136	2	GO:0098651
GeneOntologyCellularComponent	network-forming collagen trimer	COL4A2 COL4A4	1.15e-03	8	136	2	GO:0098642
GeneOntologyCellularComponent	collagen network	COL4A2 COL4A4	1.15e-03	8	136	2	GO:0098645
GeneOntologyCellularComponent	RNA polymerase III transcription regulator complex	BDP1 GTF3C2	1.47e-03	9	136	2	GO:0090576
Domain	EGF_1	CNTNAP3B VASN CNTNAP3 LAMA4 MATN4 CUBN SSPOP ITGB2 HMCN2 TENM1 NRG3 EGFL8 FBN3	5.02e-08	255	137	13	PS00022
Domain	FA58C	CNTNAP3B DDR2 CNTNAP3 SSPOP NRP1	3.65e-07	21	137	5	SM00231
Domain	FA58C_3	CNTNAP3B DDR2 CNTNAP3 SSPOP NRP1	3.65e-07	21	137	5	PS50022
Domain	FA58C_1	CNTNAP3B DDR2 CNTNAP3 SSPOP NRP1	3.65e-07	21	137	5	PS01285
Domain	FA58C_2	CNTNAP3B DDR2 CNTNAP3 SSPOP NRP1	3.65e-07	21	137	5	PS01286
Domain	EGF_2	CNTNAP3B VASN CNTNAP3 MATN4 CUBN SSPOP ITGB2 HMCN2 TENM1 NRG3 EGFL8 FBN3	6.00e-07	265	137	12	PS01186
Domain	F5_F8_type_C	CNTNAP3B DDR2 CNTNAP3 SSPOP NRP1	7.50e-07	24	137	5	PF00754
Domain	FA58C	CNTNAP3B DDR2 CNTNAP3 SSPOP NRP1	7.50e-07	24	137	5	IPR000421
Domain	EGF	CNTNAP3B VASN CNTNAP3 LAMA4 MATN4 CUBN GPR179 TENM1 NRG3 EGFL8 FBN3	1.30e-06	235	137	11	SM00181
Domain	EGF_3	CNTNAP3B VASN CNTNAP3 MATN4 CUBN SSPOP HMCN2 TENM1 NRG3 EGFL8 FBN3	1.30e-06	235	137	11	PS50026
Domain	EGF-like_dom	CNTNAP3B VASN CNTNAP3 LAMA4 MATN4 CUBN HMCN2 TENM1 NRG3 EGFL8 FBN3	2.29e-06	249	137	11	IPR000742
Domain	EGF-like_CS	VASN CNTNAP3 LAMA4 MATN4 CUBN ITGB2 HMCN2 TENM1 NRG3 EGFL8 FBN3	3.60e-06	261	137	11	IPR013032
Domain	EGF	VASN CNTNAP3 MATN4 CUBN NRG3 EGFL8 FBN3	4.00e-05	126	137	7	PF00008
Domain	CUB	ADAMTS13 CUBN CDCP1 NRP1 PCOLCE2	4.27e-05	53	137	5	PS01180
Domain	CUB_dom	ADAMTS13 CUBN CDCP1 NRP1 PCOLCE2	6.08e-05	57	137	5	IPR000859
Domain	Collagen	COL4A2 COL4A4 COL7A1 SFTPA2 SFTPA1	4.04e-04	85	137	5	IPR008160
Domain	Collagen	COL4A2 COL4A4 COL7A1 SFTPA2 SFTPA1	4.04e-04	85	137	5	PF01391
Domain	EGF_CA	MATN4 CUBN HMCN2 EGFL8 FBN3	4.27e-04	86	137	5	PF07645
Domain	-	CUBN CDCP1 NRP1 PCOLCE2	5.71e-04	52	137	4	2.60.120.290
Domain	PDZ	DLG5 LNX2 SIPA1 AHNAK SCRIB PDZRN3	6.08e-04	141	137	6	PF00595
Domain	Galactose-bd-like	CNTNAP3B DDR2 CNTNAP3 SSPOP NRP1	6.42e-04	94	137	5	IPR008979
Domain	Peptidase_M12B_ADAM-TS	ADAMTS1 ADAMTS13 ADAMTS7	6.98e-04	24	137	3	IPR013273
Domain	PDZ	DLG5 LNX2 SIPA1 AHNAK SCRIB PDZRN3	7.85e-04	148	137	6	SM00228
Domain	C4	COL4A2 COL4A4	7.86e-04	6	137	2	SM00111
Domain	Collagen_VI_NC	COL4A2 COL4A4	7.86e-04	6	137	2	IPR001442
Domain	NC1_IV	COL4A2 COL4A4	7.86e-04	6	137	2	PS51403
Domain	-	COL4A2 COL4A4	7.86e-04	6	137	2	2.170.240.10
Domain	C4	COL4A2 COL4A4	7.86e-04	6	137	2	PF01413
Domain	-	DLG5 LNX2 SIPA1 AHNAK SCRIB PDZRN3	8.41e-04	150	137	6	2.30.42.10
Domain	ASX_HYDROXYL	MATN4 CUBN HMCN2 EGFL8 FBN3	8.51e-04	100	137	5	PS00010
Domain	PDZ	DLG5 LNX2 SIPA1 AHNAK SCRIB PDZRN3	8.71e-04	151	137	6	PS50106
Domain	PDZ	DLG5 LNX2 SIPA1 AHNAK SCRIB PDZRN3	9.01e-04	152	137	6	IPR001478
Domain	EGF-type_Asp/Asn_hydroxyl_site	MATN4 CUBN HMCN2 EGFL8 FBN3	1.11e-03	106	137	5	IPR000152
Domain	CTDL_fold	COL4A2 COL4A4 PLA2R1 SFTPA2 SFTPA1	1.15e-03	107	137	5	IPR016187
Domain	TSP_1	ADAMTS1 ADAMTS13 SSPOP ADAMTS7	1.18e-03	63	137	4	PF00090
Domain	TSP1	ADAMTS1 ADAMTS13 SSPOP ADAMTS7	1.33e-03	65	137	4	SM00209
Domain	TSP1_rpt	ADAMTS1 ADAMTS13 SSPOP ADAMTS7	1.33e-03	65	137	4	IPR000884
Domain	TSP1	ADAMTS1 ADAMTS13 SSPOP ADAMTS7	1.33e-03	65	137	4	PS50092
Domain	-	DDR2 CNTNAP3 SSPOP NRP1	2.04e-03	73	137	4	2.60.120.260
Domain	EGF_CA	MATN4 CUBN HMCN2 EGFL8 FBN3	2.06e-03	122	137	5	SM00179
Domain	EGF-like_Ca-bd_dom	MATN4 CUBN HMCN2 EGFL8 FBN3	2.21e-03	124	137	5	IPR001881
Domain	LAM_G_DOMAIN	CNTNAP3B CNTNAP3 LAMA4	2.70e-03	38	137	3	PS50025
Domain	VWFA	COL7A1 MATN4 ITGB2 HMCN2	3.11e-03	82	137	4	PS50234
Domain	DISINTEGRIN_1	ADAMTS1 ADAMTS13 ADAMTS7	3.13e-03	40	137	3	PS00427
Domain	Reprolysin	ADAMTS1 ADAMTS13 ADAMTS7	3.13e-03	40	137	3	PF01421
Domain	Laminin_G_2	CNTNAP3B CNTNAP3 LAMA4	3.13e-03	40	137	3	PF02210
Domain	ADAM_MEPRO	ADAMTS1 ADAMTS13 ADAMTS7	3.13e-03	40	137	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS1 ADAMTS13 ADAMTS7	3.13e-03	40	137	3	PS50214
Domain	Peptidase_M12B	ADAMTS1 ADAMTS13 ADAMTS7	3.13e-03	40	137	3	IPR001590
Domain	Disintegrin_dom	ADAMTS1 ADAMTS13 ADAMTS7	3.36e-03	41	137	3	IPR001762
Domain	C8	SSPOP MUC5AC	3.36e-03	12	137	2	PF08742
Domain	TIL	SSPOP MUC5AC	3.36e-03	12	137	2	PF01826
Domain	VWA	COL7A1 MATN4 ITGB2 HMCN2	3.40e-03	84	137	4	SM00327
Domain	C-type_lectin_CS	PLA2R1 SFTPA2 SFTPA1	3.85e-03	43	137	3	IPR018378
Domain	Unchr_dom_Cys-rich	SSPOP MUC5AC	3.95e-03	13	137	2	IPR014853
Domain	C8	SSPOP MUC5AC	3.95e-03	13	137	2	SM00832
Domain	LamG	CNTNAP3B CNTNAP3 LAMA4	4.10e-03	44	137	3	SM00282
Domain	Ldl_recept_a	TMPRSS9 SSPOP LRP11	4.37e-03	45	137	3	PF00057
Domain	TIL_dom	SSPOP MUC5AC	4.59e-03	14	137	2	IPR002919
Domain	-	TMPRSS9 SSPOP LRP11	4.66e-03	46	137	3	4.10.400.10
Domain	LDLRA_1	TMPRSS9 SSPOP LRP11	5.25e-03	48	137	3	PS01209
Domain	CUB	CUBN NRP1 PCOLCE2	5.56e-03	49	137	3	PF00431
Domain	LDrepeatLR_classA_rpt	TMPRSS9 SSPOP LRP11	5.56e-03	49	137	3	IPR002172
Domain	LDLa	TMPRSS9 SSPOP LRP11	5.56e-03	49	137	3	SM00192
Domain	LDLRA_2	TMPRSS9 SSPOP LRP11	5.56e-03	49	137	3	PS50068
Domain	ConA-like_dom	CNTNAP3B CNTNAP3 LAMA4 NRP1 TRIM11 NEURL4	5.59e-03	219	137	6	IPR013320
Domain	EGF_Ca-bd_CS	CUBN HMCN2 EGFL8 FBN3	5.67e-03	97	137	4	IPR018097
Domain	CUB	CUBN NRP1 PCOLCE2	5.88e-03	50	137	3	SM00042
Domain	Growth_fac_rcpt_	MATN4 CUBN GPR179 HMCN2 FBN3	5.89e-03	156	137	5	IPR009030
Domain	VWF_type-D	SSPOP MUC5AC	5.99e-03	16	137	2	IPR001846
Domain	VWFD	SSPOP MUC5AC	5.99e-03	16	137	2	PS51233
Domain	VWD	SSPOP MUC5AC	5.99e-03	16	137	2	SM00216
Domain	VWD	SSPOP MUC5AC	5.99e-03	16	137	2	PF00094
Domain	EGF_CA	CUBN HMCN2 EGFL8 FBN3	6.09e-03	99	137	4	PS01187
Domain	VWF_A	COL7A1 MATN4 ITGB2 HMCN2	6.09e-03	99	137	4	IPR002035
Domain	EMI	SSPOP EGFL8	6.76e-03	17	137	2	PS51041
Domain	Znf_RING_CS	MKRN3 RNF223 LNX2 TRIM11 PDZRN3	7.06e-03	163	137	5	IPR017907
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL4A2 COL4A4 COL7A1 ADAMTS1 DDR2 LAMA4 MATN4 ITGB2 PCOLCE2 FBN3	2.53e-05	300	92	10	M610
Pathway	REACTOME_LAMININ_INTERACTIONS	COL4A2 COL4A4 COL7A1 LAMA4	4.09e-05	30	92	4	M27216
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS1 ADAMTS13 SSPOP ADAMTS7 MUC5AC	8.00e-05	68	92	5	M27303
Pathway	REACTOME_ANCHORING_FIBRIL_FORMATION	COL4A2 COL4A4 COL7A1	1.16e-04	15	92	3	M27161
Pathway	REACTOME_LAMININ_INTERACTIONS	COL4A2 COL4A4 LAMA4	1.16e-04	15	92	3	MM14922
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS1 ADAMTS13 SSPOP ADAMTS7	1.17e-04	39	92	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS1 ADAMTS13 SSPOP ADAMTS7	1.17e-04	39	92	4	MM15165
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTS1 ADAMTS13 CUBN SSPOP SFTPA2 ADAMTS7 SFTPA1 MUC5AC	2.26e-04	250	92	8	M27554
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL4A2 COL4A4 COL7A1 DDR2 LAMA4 MATN4 ITGB2 PCOLCE2	2.79e-04	258	92	8	MM14572
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL4A2 COL4A4 COL7A1 LAMA4 MATN4 SFTPA2 HMCN2 SFTPA1 PCOLCE2	2.97e-08	167	141	9	22159717
Pubmed	The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis.	KRT5 SAFB SFTPA2 SFTPA1 MUC5AC	1.88e-07	32	141	5	28546511
Pubmed	In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.	CNTNAP3B CNTNAP3 NRG3	1.29e-06	6	141	3	34143959
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	POLRMT KIF7 SLC25A12 SLMAP SAFB2 TNKS1BP1 NEURL4 VARS1	2.64e-06	212	141	8	33853758
Pubmed	Placing the HIRA histone chaperone complex in the chromatin landscape.	BDP1 E2F1 SMARCC1 CABIN1	7.48e-06	31	141	4	23602572
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	COL4A2 COL4A4 COL7A1 DPY19L1 VASN CNTNAP3 LAMA4 NRP1 PLA2R1 P4HTM JMJD8 LRP11 TNKS1BP1 PCOLCE2 SCRIB NME3 PBXIP1	7.96e-06	1201	141	17	35696571
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	HK3 POLRMT IRF3 SNX33 MEIS1 KIF7 GTF3C2 NFATC1 RECQL4 SLMAP SMARCC1 SCRIB CABIN1 VARS1	1.10e-05	857	141	14	25609649
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ADAMTS1 BTBD18 POLRMT CRACR2B SIPA1 KIF7 ARHGEF40 ATP2C1 SLC25A12 HMCN2 INTS13 SMARCC1 SCRIB CRYBG3 PDZRN3 BAHCC1	1.28e-05	1116	141	16	31753913
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS1 ADAMTS13 ADAMTS7	1.40e-05	12	141	3	25770910
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS1 ADAMTS13 CUBN SSPOP ADAMTS7	1.40e-05	75	141	5	20637190
Pubmed	Surfactant protein-A binds group B streptococcus enhancing phagocytosis and clearance from lungs of surfactant protein-A-deficient mice.	SFTPA2 SFTPA1	1.63e-05	2	141	2	9922219
Pubmed	Maternal surfactant protein A influences the immunoprotective properties of milk in a murine model.	SFTPA2 SFTPA1	1.63e-05	2	141	2	24858142
Pubmed	Breast carcinoma with brain metastases: clinical analysis and immunoprofile on tissue microarrays.	KRT5 KRT75	1.63e-05	2	141	2	21427063
Pubmed	Scaffold attachment factors SAFB1 and SAFB2: Innocent bystanders or critical players in breast tumorigenesis?	SAFB SAFB2	1.63e-05	2	141	2	14587024
Pubmed	Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome.	SFTPA2 SFTPA1	1.63e-05	2	141	2	24954098
Pubmed	Surfactant protein A modulates neuroinflammation in adult mice upon pulmonary infection.	SFTPA2 SFTPA1	1.63e-05	2	141	2	38964703
Pubmed	ZNF674: a new kruppel-associated box-containing zinc-finger gene involved in nonsyndromic X-linked mental retardation.	ZNF674 KRBOX4	1.63e-05	2	141	2	16385466
Pubmed	Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants.	SFTPA2 SFTPA1	1.63e-05	2	141	2	34917085
Pubmed	Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation.	SFTPA2 SFTPA1	1.63e-05	2	141	2	22219327
Pubmed	Surfactant protein A is a principal and oxidation-sensitive microbial permeabilizing factor in the alveolar lining fluid.	SFTPA2 SFTPA1	1.63e-05	2	141	2	15890661
Pubmed	Enhanced lung injury and delayed clearance of Pneumocystis carinii in surfactant protein A-deficient mice: attenuation of cytokine responses and reactive oxygen-nitrogen species.	SFTPA2 SFTPA1	1.63e-05	2	141	2	15385504
Pubmed	A TLR4-interacting SPA4 peptide inhibits LPS-induced lung inflammation.	SFTPA2 SFTPA1	1.63e-05	2	141	2	23475791
Pubmed	Surfactant protein A associated with respiratory distress syndrome in Korean preterm infants: evidence of ethnic difference.	SFTPA2 SFTPA1	1.63e-05	2	141	2	23038062
Pubmed	Characterization of the human IRF-3 promoter and its regulation by the transcription factor E2F1.	E2F1 IRF3	1.63e-05	2	141	2	19826915
Pubmed	Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences.	SFTPA2 SFTPA1	1.63e-05	2	141	2	29394894
Pubmed	Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice.	SFTPA2 SFTPA1	1.63e-05	2	141	2	17307210
Pubmed	Surfactant protein A modulates induction of regulatory T cells via TGF-β.	SFTPA2 SFTPA1	1.63e-05	2	141	2	22474025
Pubmed	Surfactant protein A promotes western diet-induced hepatic steatosis and fibrosis in mice.	SFTPA2 SFTPA1	1.63e-05	2	141	2	38553537
Pubmed	Surfactant protein A reduces TLR4 and inflammatory cytokine mRNA levels in neonatal mouse ileum.	SFTPA2 SFTPA1	1.63e-05	2	141	2	33510368
Pubmed	Genetic complexity of the human innate host defense molecules, surfactant protein A1 (SP-A1) and SP-A2--impact on function.	SFTPA2 SFTPA1	1.63e-05	2	141	2	19392648
Pubmed	Surfactant protein A suppresses lipopolysaccharide-induced IL-10 production by murine macrophages.	SFTPA2 SFTPA1	1.63e-05	2	141	2	11342662
Pubmed	Surfactant protein A-deficient mice are susceptible to group B streptococcal infection.	SFTPA2 SFTPA1	1.63e-05	2	141	2	9126996
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	1.63e-05	2	141	2	26807827
Pubmed	Lung development in the mouse embryo.	SFTPA2 SFTPA1	1.63e-05	2	141	2	2050021
Pubmed	Structures of collagen IV globular domains: insight into associated pathologies, folding and network assembly.	COL4A2 COL4A4	1.63e-05	2	141	2	30443360
Pubmed	Effects of surfactant protein-A on the interaction of Pneumocystis murina with its host at different stages of the infection in mice.	SFTPA2 SFTPA1	1.63e-05	2	141	2	19335775
Pubmed	Altered surfactant protein A gene expression and protein metabolism associated with repeat exposure to inhaled endotoxin.	SFTPA2 SFTPA1	1.63e-05	2	141	2	12922979
Pubmed	Differences in the alveolar macrophage toponome in humanized SP-A1 and SP-A2 transgenic mice.	SFTPA2 SFTPA1	1.63e-05	2	141	2	33141765
Pubmed	Innate immunity of surfactant protein A in experimental otitis media.	SFTPA2 SFTPA1	1.63e-05	2	141	2	31378117
Pubmed	Immunosuppressed surfactant protein A-deficient mice have increased susceptibility to Pneumocystis carinii infection.	SFTPA2 SFTPA1	1.63e-05	2	141	2	11237812
Pubmed	Surfactant protein A deficiency exacerbates renal interstitial fibrosis following obstructive injury in mice.	SFTPA2 SFTPA1	1.63e-05	2	141	2	27916681
Pubmed	Surfactant protein A inhibits alveolar macrophage cytokine production by CD14-independent pathway.	SFTPA2 SFTPA1	1.63e-05	2	141	2	12959932
Pubmed	Surfactant protein secreted by the maturing mouse fetal lung acts as a hormone that signals the initiation of parturition.	SFTPA2 SFTPA1	1.63e-05	2	141	2	15044702
Pubmed	Structural comparison of recombinant pulmonary surfactant protein SP-A derived from two human coding sequences: implications for the chain composition of natural human SP-A.	SFTPA2 SFTPA1	1.63e-05	2	141	2	1986781
Pubmed	Surfactant protein A is a required mediator of keratinocyte growth factor after experimental marrow transplantation.	SFTPA2 SFTPA1	1.63e-05	2	141	2	12740217
Pubmed	Surfactant protein-A plays an important role in lung surfactant clearance: evidence using the surfactant protein-A gene-targeted mouse.	SFTPA2 SFTPA1	1.63e-05	2	141	2	18083768
Pubmed	Direct repression of the human IRF-3 promoter by E2F1.	E2F1 IRF3	1.63e-05	2	141	2	21225257
Pubmed	The alveolar macrophage toponome of female SP-A knockout mice differs from that of males before and after SP-A1 rescue.	SFTPA2 SFTPA1	1.63e-05	2	141	2	35322074
Pubmed	Characteristics of surfactant from SP-A-deficient mice.	SFTPA2 SFTPA1	1.63e-05	2	141	2	9700084
Pubmed	Novel role for surfactant protein A in gastrointestinal graft-versus-host disease.	SFTPA2 SFTPA1	1.63e-05	2	141	2	22508928
Pubmed	Relationship between surfactant protein A polymorphisms and allergic rhinitis in a Chinese Han population.	SFTPA2 SFTPA1	1.63e-05	2	141	2	20963503
Pubmed	Type IV pilus glycosylation mediates resistance of Pseudomonas aeruginosa to opsonic activities of the pulmonary surfactant protein A.	SFTPA2 SFTPA1	1.63e-05	2	141	2	25605768
Pubmed	Role of surfactant protein-A in nitric oxide production and mycoplasma killing in congenic C57BL/6 mice.	SFTPA2 SFTPA1	1.63e-05	2	141	2	12959946
Pubmed	Scaffold attachment factor B (SAFB)1 and SAFB2 cooperatively inhibit the intranuclear mobility and function of ERα.	SAFB SAFB2	1.63e-05	2	141	2	22566185
Pubmed	Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome.	SFTPA2 SFTPA1	1.63e-05	2	141	2	31354704
Pubmed	Signaling Pathways That Mediate Alveolar Macrophage Activation by Surfactant Protein A and IL-4.	SFTPA2 SFTPA1	1.63e-05	2	141	2	35444643
Pubmed	Surfactant-associated protein A inhibits LPS-induced cytokine and nitric oxide production in vivo.	SFTPA2 SFTPA1	1.63e-05	2	141	2	10749762
Pubmed	The flagellum of Pseudomonas aeruginosa is required for resistance to clearance by surfactant protein A.	SFTPA2 SFTPA1	1.63e-05	2	141	2	17593964
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	1.63e-05	2	141	2	31150793
Pubmed	Studies of the structure of lung surfactant protein SP-A.	SFTPA2 SFTPA1	1.63e-05	2	141	2	2610270
Pubmed	Surfactant protein-A--deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of influenza A virus.	SFTPA2 SFTPA1	1.63e-05	2	141	2	11867335
Pubmed	Pneumocystis murina colonization in immunocompetent surfactant protein A deficient mice following environmental exposure.	SFTPA2 SFTPA1	1.63e-05	2	141	2	19228388
Pubmed	SP-A preserves airway homeostasis during Mycoplasma pneumoniae infection in mice.	SFTPA2 SFTPA1	1.63e-05	2	141	2	19494306
Pubmed	An 11-nt sequence polymorphism at the 3'UTR of human SFTPA1 and SFTPA2 gene variants differentially affect gene expression levels and miRNA regulation in cell culture.	SFTPA2 SFTPA1	1.63e-05	2	141	2	24793167
Pubmed	Characterization of a second human pulmonary surfactant-associated protein SP-A gene.	SFTPA2 SFTPA1	1.63e-05	2	141	2	1372511
Pubmed	Lung effector memory and activated CD4+ T cells display enhanced proliferation in surfactant protein A-deficient mice during allergen-mediated inflammation.	SFTPA2 SFTPA1	1.63e-05	2	141	2	21257967
Pubmed	The Pseudomonas aeruginosa flagellum confers resistance to pulmonary surfactant protein-A by impacting the production of exoproteases through quorum-sensing.	SFTPA2 SFTPA1	1.63e-05	2	141	2	21205009
Pubmed	Surfactant protein A binds flagellin enhancing phagocytosis and IL-1β production.	SFTPA2 SFTPA1	1.63e-05	2	141	2	24312669
Pubmed	Correlation analysis between single nucleotide polymorphisms of pulmonary surfactant protein A gene and pulmonary tuberculosis in the Han population in China.	SFTPA2 SFTPA1	1.63e-05	2	141	2	24984162
Pubmed	Effect of cysteine 85 on biochemical properties and biological function of human surfactant protein A variants.	SFTPA2 SFTPA1	1.63e-05	2	141	2	17580966
Pubmed	Isolation and characterization of cDNA clones for the 35-kDa pulmonary surfactant-associated protein.	SFTPA2 SFTPA1	1.63e-05	2	141	2	3755136
Pubmed	SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells.	SAFB SAFB2	1.63e-05	2	141	2	19901029
Pubmed	Surfactant protein-A suppresses eosinophil-mediated killing of Mycoplasma pneumoniae in allergic lungs.	SFTPA2 SFTPA1	1.63e-05	2	141	2	22384248
Pubmed	Surfactant protein A enhances production of secretory leukoprotease inhibitor and protects it from cleavage by matrix metalloproteinases.	SFTPA2 SFTPA1	1.63e-05	2	141	2	19155504
Pubmed	Surfactant Protein A can Affect the Surface Tension of the Eustachian Tube and Macrophage Migration.	SFTPA2 SFTPA1	1.63e-05	2	141	2	36102297
Pubmed	The collagen-like region of surfactant protein A (SP-A) is required for correction of surfactant structural and functional defects in the SP-A null mouse.	SFTPA2 SFTPA1	1.63e-05	2	141	2	11504713
Pubmed	Nrp1, a Neuronal Regulator, Enhances DDR2-ERK-Runx2 Cascade in Osteoblast Differentiation via Suppression of DDR2 Degradation.	DDR2 NRP1	1.63e-05	2	141	2	25924845
Pubmed	Polymorphisms in the surfactant protein a gene are associated with the susceptibility to recurrent urinary tract infection in chinese women.	SFTPA2 SFTPA1	1.63e-05	2	141	2	20448439
Pubmed	Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products.	SFTPA2 SFTPA1	1.63e-05	2	141	2	20048345
Pubmed	Functional assessment and phenotypic heterogeneity of SFTPA1 and SFTPA2 mutations in interstitial lung diseases and lung cancer.	SFTPA2 SFTPA1	1.63e-05	2	141	2	32855221
Pubmed	Type IV pilus of Pseudomonas aeruginosa confers resistance to antimicrobial activities of the pulmonary surfactant protein-A.	SFTPA2 SFTPA1	1.63e-05	2	141	2	24080545
Pubmed	Murine pulmonary surfactant SP-A gene: cloning, sequence, and transcriptional activity.	SFTPA2 SFTPA1	1.63e-05	2	141	2	1443158
Pubmed	Surfactant Protein A and B Gene Polymorphisms and Risk of Respiratory Distress Syndrome in Late-Preterm Neonates.	SFTPA2 SFTPA1	1.63e-05	2	141	2	27835691
Pubmed	Genetic Variation in Surfactant Protein-A2 Delays Resolution of Eosinophilia in Asthma.	SFTPA2 SFTPA1	1.63e-05	2	141	2	31350355
Pubmed	Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2.	SFTPA2 SFTPA1	1.63e-05	2	141	2	23069847
Pubmed	Ablation of SP-A has a negative impact on the susceptibility of mice to Klebsiella pneumoniae infection after ozone exposure: sex differences.	SFTPA2 SFTPA1	1.63e-05	2	141	2	19055785
Pubmed	Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions.	SFTPA2 SFTPA1	1.63e-05	2	141	2	34484180
Pubmed	Surfactant protein A limits Pneumocystis murina infection in immunosuppressed C3H/HeN mice and modulates host response during infection.	SFTPA2 SFTPA1	1.63e-05	2	141	2	15857803
Pubmed	Surfactant protein-A reduces translocation of mediators from the lung into the circulation.	SFTPA2 SFTPA1	1.63e-05	2	141	2	20715984
Pubmed	No germline mutations in supposed tumour suppressor genes SAFB1 and SAFB2 in familial breast cancer with linkage to 19p.	SAFB SAFB2	1.63e-05	2	141	2	19077293
Pubmed	Low SAFB levels are associated with worse outcome in breast cancer patients.	SAFB SAFB2	1.63e-05	2	141	2	19137425
Pubmed	Cryptococcus neoformans is resistant to surfactant protein A mediated host defense mechanisms.	SFTPA2 SFTPA1	1.63e-05	2	141	2	18159253
Pubmed	Regulatory roles of SP-A and exosomes in pneumonia-induced acute lung and kidney injuries.	SFTPA2 SFTPA1	1.63e-05	2	141	2	37256132
Pubmed	Surfactant protein a attenuates generalized and localized neuroinflammation in neonatal mice.	SFTPA2 SFTPA1	1.63e-05	2	141	2	36871846
Pubmed	Surfactant Protein A, a Novel Regulator for Smooth Muscle Phenotypic Modulation and Vascular Remodeling-Brief Report.	SFTPA2 SFTPA1	1.63e-05	2	141	2	33267655
Pubmed	Human SP-A protein variants derived from one or both genes stimulate TNF-alpha production in the THP-1 cell line.	SFTPA2 SFTPA1	1.63e-05	2	141	2	10781424
Pubmed	SP-A is necessary for increased clearance of alveolar DPPC with hyperventilation or secretagogues.	SFTPA2 SFTPA1	1.63e-05	2	141	2	12676766
Pubmed	Repression of interferon regulatory factor 3 by the Epstein-Barr virus immediate-early protein Rta is mediated through E2F1 in HeLa cells.	E2F1 IRF3	1.63e-05	2	141	2	24535579
Pubmed	Structural characterisation of human proteinosis surfactant protein A.	SFTPA2 SFTPA1	1.63e-05	2	141	2	11087951
Pubmed	Surfactant protein-A inhibits Aspergillus fumigatus-induced allergic T-cell responses.	SFTPA2 SFTPA1	1.63e-05	2	141	2	16120217
GeneFamily	PDZ domain containing	DLG5 LNX2 SIPA1 AHNAK SCRIB PDZRN3	8.64e-05	152	86	6	1220
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS1 ADAMTS13 ADAMTS7	9.53e-05	19	86	3	50
GeneFamily	Collectins	SFTPA2 SFTPA1	9.82e-04	10	86	2	491
GeneFamily	Collagens	COL4A2 COL4A4 COL7A1	1.36e-03	46	86	3	490
GeneFamily	Ring finger proteins	MKRN3 RNF223 LNX2 TRIM11 MARCHF11 PDZRN3	1.99e-03	275	86	6	58
GeneFamily	Immunoglobulin like domain containing	SEMA4G IGDCC4 HMCN2 ALPK3 GPA33	2.28e-03	193	86	5	594
Coexpression	NABA_MATRISOME	COL4A2 COL4A4 COL7A1 ADAMTS1 LAMA4 MATN4 ADAMTS13 SSPOP SEMA4G P4HTM SFTPA2 HMCN2 ADAMTS7 PODN SFTPA1 PCOLCE2 MST1L NRG3 EGFL8 MUC5AC FBN3	1.29e-07	1026	140	21	M5889
Coexpression	NABA_MATRISOME	COL4A2 COL4A4 COL7A1 ADAMTS1 LAMA4 MATN4 ADAMTS13 SSPOP SEMA4G P4HTM SFTPA2 HMCN2 ADAMTS7 PODN SFTPA1 PCOLCE2 MST1L NRG3 EGFL8 MUC5AC	4.35e-07	1008	140	20	MM17056
Coexpression	NABA_CORE_MATRISOME	COL4A2 COL4A4 COL7A1 LAMA4 MATN4 SSPOP HMCN2 PODN PCOLCE2 FBN3	2.38e-06	275	140	10	M5884
Coexpression	HEBERT_MATRISOME_TNBC_LUNG_METASTASIS	COL4A2 COL4A4 COL7A1 SFTPA1	6.38e-06	23	140	4	M48001
Coexpression	GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_DN	IL12RB1 COL7A1 ZNF142 POLRMT SNX33 JMJD8 ZFYVE26 PBXIP1	1.26e-05	200	140	8	M6208
Coexpression	NABA_CORE_MATRISOME	COL4A2 COL4A4 COL7A1 LAMA4 MATN4 SSPOP HMCN2 PODN PCOLCE2	1.55e-05	270	140	9	MM17057
Coexpression	HAY_BONE_MARROW_STROMAL	COL4A2 COL7A1 ADAMTS1 VASN DDR2 PHLDA3 LAMA4 IGDCC4 KIF7 NRP1 TNFRSF12A PLA2R1 SAMD11 PODN TNKS1BP1	1.59e-05	767	140	15	M39209
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	COL4A2 ADAMTS1 VASN DDR2 LAMA4 MEIS1 SAMD11 PODN PDZRN3	1.60e-08	200	141	9	954fee8425673e76198be414f5f6c4e3597c1919
ToppCell	390C-Fibroblasts\|390C / Donor, Lineage, Cell class and subclass (all cells)	COL4A2 ADAMTS1 VASN DDR2 PHLDA3 LAMA4 MEIS1 PODN PDZRN3	1.60e-08	200	141	9	3abe0f017fee6057ba73bd661a2bc8ec9e2bfe38
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B DPY19L1 DDR2 CNTNAP3 NRP1 TRPM3 TENM1 CRYBG3	8.32e-08	173	141	8	95c723b09254ae7131fe5ba0841472502e83269b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B DPY19L1 DDR2 CNTNAP3 NRP1 TRPM3 TENM1 CRYBG3	9.50e-08	176	141	8	72a2a01618ce836bc843395d5095e9090759b4a6
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B DPY19L1 DDR2 CNTNAP3 NRP1 TRPM3 TENM1 CRYBG3	9.93e-08	177	141	8	4c069f0d044a96118090b85ca592a21d6b5d9399
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HK3 PHLDA3 ITGB2 NRP1 TRPV2 ALPK3 PCOLCE2 GPA33	1.04e-07	178	141	8	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B DPY19L1 DDR2 CNTNAP3 NRP1 ARHGAP31 TENM1 CRYBG3	1.13e-07	180	141	8	e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B DPY19L1 DDR2 CNTNAP3 NRP1 TRPM3 TENM1 CRYBG3	1.18e-07	181	141	8	08f44323bf71b6004a921bbc969c954c75feeb66
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT5 LAMA4 CRACR2B NRP1 PLA2R1 PGPEP1L ARHGEF40 ARHGAP31	1.23e-07	182	141	8	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT5 LAMA4 CRACR2B NRP1 PLA2R1 PGPEP1L ARHGEF40 ARHGAP31	1.23e-07	182	141	8	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	DDR2 LAMA4 MEIS1 IGDCC4 SSC5D HMCN2 PODN PDZRN3	1.39e-07	185	141	8	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DDR2 LAMA4 MEIS1 IGDCC4 SSC5D SAMD11 PODN PDZRN3	1.85e-07	192	141	8	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	DDR2 LAMA4 MEIS1 IGDCC4 KIF7 SAMD11 PODN PDZRN3	1.85e-07	192	141	8	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A2 DDR2 LAMA4 IGDCC4 SSC5D SAMD11 PODN PDZRN3	1.93e-07	193	141	8	b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADAMTS1 DDR2 LAMA4 MEIS1 IGDCC4 SAMD11 PODN PDZRN3	1.93e-07	193	141	8	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	15-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	COL4A2 ADAMTS1 VASN DDR2 MATN4 SAMD11 PODN PCOLCE2	2.17e-07	196	141	8	7e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCell	COPD-Stromal\|COPD / Disease state, Lineage and Cell class	COL4A2 ADAMTS1 VASN DDR2 LAMA4 MEIS1 PODN PDZRN3	2.26e-07	197	141	8	d5390d86acaa8c39f1da893e8d2271f9ed2951d7
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	VASN DDR2 LAMA4 SSC5D SAMD11 TENM1 PODN PDZRN3	2.44e-07	199	141	8	e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCell	390C-Fibroblasts-Fibroblast-H-\|390C / Donor, Lineage, Cell class and subclass (all cells)	VASN DDR2 PHLDA3 LAMA4 MEIS1 SAMD11 PODN PDZRN3	2.53e-07	200	141	8	ec7d6a08e34bcad5b3bbff56ebef96ae17e4cefd
ToppCell	(5)_Fibroblast-H\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	ADAMTS1 VASN LAMA4 MEIS1 TNFRSF12A SAMD11 PODN PDZRN3	2.53e-07	200	141	8	94e77a1082ade6fad93a37168e037af8aefe7ff4
ToppCell	390C-Fibroblasts-Fibroblast-H\|390C / Donor, Lineage, Cell class and subclass (all cells)	VASN DDR2 PHLDA3 LAMA4 MEIS1 SAMD11 PODN PDZRN3	2.53e-07	200	141	8	671e731977c58a0c44c36b56422085d93d999aad
ToppCell	Biopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ADAMTS1 DDR2 LAMA4 IGDCC4 KIF7 TET1 PODN PDZRN3	2.53e-07	200	141	8	cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCell	343B-Epithelial_cells-Epithelial-E_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VASN LAMA4 IGDCC4 SSC5D SAMD11 PODN FBN3	5.91e-07	153	141	7	d5f5399ebbbff508c96ce7f01272716b61597ab5
ToppCell	343B-Epithelial_cells-Epithelial-E_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VASN LAMA4 IGDCC4 SSC5D SAMD11 PODN FBN3	5.91e-07	153	141	7	32cf4ca828d228f23366480305592f9813fed7ff
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A4 RNF223 KCNH3 TG PGPEP1L BEND7 RECQL4	9.43e-07	164	141	7	cdb8cd2d6b369189ea77e4946738e2816d502e03
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A4 RNF223 KCNH3 TG PGPEP1L BEND7 RECQL4	9.43e-07	164	141	7	5dbfcdd450f652b16d97da53b528d4584b0eabcf
ToppCell	facs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A4 RNF223 KCNH3 TG PGPEP1L BEND7 RECQL4	9.43e-07	164	141	7	f1423f4434af4af9c60c8a5b0b0abec4a7df9401
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL4A4 SEMA4G GTF3C2 TRPM3 SLC49A3 FBN3	1.25e-06	108	141	6	d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A2 ADAMTS1 LAMA4 MEIS1 PGPEP1L DCLK2 PDZRN3	1.35e-06	173	141	7	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	COL4A2 COL7A1 ADAMTS1 VASN LAMA4 SAMD11 PDZRN3	1.40e-06	174	141	7	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B DPY19L1 CNTNAP3 NRP1 TRPM3 TENM1 CRYBG3	1.63e-06	178	141	7	431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCell	facs-Kidney-nan-24m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR2 E2F1 SNX33 MEIS1 SSC5D PPIP5K1 PCOLCE2	1.76e-06	180	141	7	f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B DPY19L1 CNTNAP3 NRP1 TRPM3 TENM1 CRYBG3	1.76e-06	180	141	7	b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 IGDCC4 HMCN2 TRPM3 ALPK3 TENM1	1.82e-06	181	141	7	af92b8b7f455210dab502ef6964f3a0162180759
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT5 LAMA4 CRACR2B NRP1 PLA2R1 PGPEP1L ARHGEF40	1.89e-06	182	141	7	b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MKRN3 COL4A4 DDR2 CNTNAP3 ADAMTS7 TENM1	2.00e-06	117	141	6	0602bbad908cb28c5093b74d717da5f2af577943
ToppCell	COPD-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	PHLDA3 GPRIN3 NRP1 TRPV2 ALPK3 PCOLCE2 GPA33	2.03e-06	184	141	7	7fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A2 ADAMTS1 VASN DDR2 KIF7 TENM1 PODN	2.11e-06	185	141	7	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 DDR2 ADAMTS13 MEIS1 PODN NRG3 PDZRN3	2.11e-06	185	141	7	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	Control-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	PHLDA3 GPRIN3 NRP1 ATP2C1 TRPV2 ALPK3 PCOLCE2	2.11e-06	185	141	7	85cb81759589a26d83676cffbf2bc37399683c10
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Control / Disease state, Lineage and Cell class	PHLDA3 GPRIN3 CDCP1 NRP1 TRPV2 ALPK3 PCOLCE2	2.43e-06	189	141	7	937e876122bc4b94372a4104e9c1a9068c232018
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B CUBN FAM135B NRP1 TRPM3 BEND7 NRG3	2.43e-06	189	141	7	28b502611829e4a24caff2562545c7db97686099
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 DDR2 LAMA4 MEIS1 NRP1 CRYBG3 PDZRN3	2.43e-06	189	141	7	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 DDR2 LAMA4 MEIS1 NRP1 CRYBG3 PDZRN3	2.51e-06	190	141	7	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 DDR2 LAMA4 MEIS1 NRP1 CRYBG3 PDZRN3	2.51e-06	190	141	7	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 DDR2 LAMA4 MEIS1 NRP1 CRYBG3 PDZRN3	2.60e-06	191	141	7	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 DDR2 LAMA4 MEIS1 NRP1 CRYBG3 PDZRN3	2.60e-06	191	141	7	806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 DDR2 LAMA4 MEIS1 NRP1 CRYBG3 PDZRN3	2.60e-06	191	141	7	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	21-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	COL4A2 ADAMTS1 DDR2 LAMA4 IGDCC4 SAMD11 PDZRN3	2.89e-06	194	141	7	749dd8113ef260e00facac09de9861d61725124a
ToppCell	Control-Stromal-Fibroblast\|Control / Disease state, Lineage and Cell class	ADAMTS1 VASN DDR2 LAMA4 MEIS1 PODN PDZRN3	3.09e-06	196	141	7	7ca94477498a84cafcdd9933ee92a6cbde76c70e
ToppCell	Control-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	ADAMTS1 VASN DDR2 LAMA4 MEIS1 PODN PDZRN3	3.09e-06	196	141	7	1ec7a4daa51b3156db97e1fd6cb925ad311bb4b5
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC71L ADAMTS1 VASN DDR2 LAMA4 PODN PDZRN3	3.19e-06	197	141	7	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	Control-Stromal\|Control / Disease state, Lineage and Cell class	ADAMTS1 VASN DDR2 LAMA4 MEIS1 PODN PDZRN3	3.30e-06	198	141	7	ae726b6b7f0a4107899be4d32ac256ffa0bd8d59
ToppCell	Fibroblasts-HLA-DRA_high_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	COL4A2 ADAMTS1 DDR2 LAMA4 SSC5D PODN TNKS1BP1	3.30e-06	198	141	7	e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCell	tumor_Lung-Fibroblasts-COL14A1+_matrix_FBs\|tumor_Lung / Location, Cell class and cell subclass	ADAMTS1 VASN DDR2 IGDCC4 SAMD11 PODN PDZRN3	3.30e-06	198	141	7	74f2c7ef702b25a5b99e56121229e678ed992524
ToppCell	IPF-Stromal\|IPF / Disease state, Lineage and Cell class	COL4A2 ADAMTS1 VASN DDR2 LAMA4 MEIS1 PDZRN3	3.30e-06	198	141	7	ece914c32c9b123b779aa9624b92e6230763a20e
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	COL4A2 TMPRSS9 BTBD18 KIF7 HMCN2 PODN PCOLCE2	3.41e-06	199	141	7	07b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A2 COL4A4 ADAMTS1 PHLDA3 LAMA4 PODN PDZRN3	3.41e-06	199	141	7	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	Biopsy_Other_PF-Mesenchymal-Myofibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	VASN DDR2 LAMA4 SSC5D SAMD11 PODN PDZRN3	3.53e-06	200	141	7	e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	VASN DDR2 LAMA4 SSC5D SAMD11 PODN PDZRN3	3.53e-06	200	141	7	6e3d1ae0ef84d3075afa40129a41169996462672
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A2 DDR2 LAMA4 NRP1 TENM1 PODN PDZRN3	3.53e-06	200	141	7	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS1 DDR2 LAMA4 MEIS1 NRP1 PODN PDZRN3	3.53e-06	200	141	7	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Biopsy_IPF-Mesenchymal\|Biopsy_IPF / Sample group, Lineage and Cell type	ADAMTS1 VASN DDR2 LAMA4 SSC5D PODN PDZRN3	3.53e-06	200	141	7	bb605b373caf3f873dc1b87d712704568e0d6040
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	COL4A2 ADAMTS1 DDR2 LAMA4 MEIS1 NRP1 PDZRN3	3.53e-06	200	141	7	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	Biopsy_Other_PF-Mesenchymal\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ADAMTS1 VASN DDR2 LAMA4 SSC5D PODN PDZRN3	3.53e-06	200	141	7	d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL7A1 VASN DDR2 SSC5D SAMD11 PODN PDZRN3	3.53e-06	200	141	7	54806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DDR2 LAMA4 MEIS1 IGDCC4 SAMD11 PODN PDZRN3	3.53e-06	200	141	7	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A2 DDR2 LAMA4 NRP1 TENM1 PODN PCOLCE2	3.53e-06	200	141	7	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	5'-Adult-LargeIntestine-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A2 ADAMTS1 VASN DDR2 LAMA4 PODN PCOLCE2	3.53e-06	200	141	7	5a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUBN SSPOP GPR179 P4HTM FMN1 SCRIB	5.21e-06	138	141	6	c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUBN SSPOP GPR179 P4HTM FMN1 SCRIB	6.14e-06	142	141	6	67d4ff3483ae34f77c3325aa0fbd3462ca19ade4
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Gkn3)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CUBN GFI1 PKP3 ALPK3 EGFL8	6.33e-06	82	141	5	ea3bdd7b871269eacb81167c6cf59a0e21bf6d83
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Gkn3)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CUBN GFI1 PKP3 ALPK3 EGFL8	6.33e-06	82	141	5	72d5a55ca7c03e9c54f865524e206b288f242017
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Gkn3)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CUBN GFI1 PKP3 ALPK3 EGFL8	6.33e-06	82	141	5	e500582511814a067852dc3bd78d19937c28ba60
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL10RA HK3 ITGB2 KCNH3 HMCN2 PCOLCE2	7.20e-06	146	141	6	b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS1 ADAMTS13 SNX33 LCMT2 NRG3 INCA1	1.09e-05	157	141	6	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	DDR2 LAMA4 MEIS1 PODN SFTPA1 PDZRN3	1.17e-05	159	141	6	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC168 SSPOP LCMT2 KCNH3 PLA2R1 PCOLCE2	1.17e-05	159	141	6	fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC168 SSPOP LCMT2 KCNH3 PLA2R1 PCOLCE2	1.17e-05	159	141	6	aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CCDC168 SSPOP LCMT2 KCNH3 PLA2R1 PCOLCE2	1.17e-05	159	141	6	8bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL4A4 LNX2 DPY19L1 PHLDA3 SLC25A12 SLC49A3	1.35e-05	163	141	6	1c014e373667be290d7fb5d24c06c6f313ac8fa3
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LAMA4 MEIS1 TNFRSF12A ARHGAP31 PCOLCE2 SCRIB	1.35e-05	163	141	6	0ab043b68e8739adcedda01165a3758cd0d22728
ToppCell	facs-Trachea-nan-18m-Epithelial-mucus_secreting_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF223 KCNH3 TG PGPEP1L BEND7 RECQL4	1.45e-05	165	141	6	7e7643834ed483aec04f513cca38d6367fda9ff8
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	CNTNAP3B KIF7 TRPM3 TET1 PDZRN3 LRRC74B	1.55e-05	167	141	6	5c82d801e3b7d7c6c967a73b94b2ee2a8da1fd6e
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MKRN3 GPRIN3 ARHGEF40 ARHGAP31 BOD1L1	1.59e-05	99	141	5	a815a887094204de30b299e8907e81ad9a39c016
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A4 MEIS1 NRP1 SSC5D PLA2R1 PRRT4	1.60e-05	168	141	6	d19a115365c5415e51c039718d7669de788fcf33
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPY19L1 CNTNAP3 NRP1 TRPM3 TENM1 PCOLCE2	1.60e-05	168	141	6	7abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A2 COL7A1 ADAMTS1 LAMA4 CRYBG3 PDZRN3	1.66e-05	169	141	6	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 GPRIN3 SSPOP PKP3 AHNAK ARHGAP45	1.71e-05	170	141	6	aff226a84e397ab58204325aa9d8b396a881986e
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 GPRIN3 SSPOP PKP3 AHNAK ARHGAP45	1.71e-05	170	141	6	6af16e6f276aec6389ece99505ba13c7edc4c4fa
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B NRP1 ARHGAP31 TRPV2 NRG3 ARHGAP45	1.89e-05	173	141	6	afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LNX2 CRACR2B MEIS1 AHNAK PPIP5K1 MUC5AC	1.95e-05	174	141	6	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L5-6_FEZF2_ANKRD20A1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DDR2 CNTNAP3 NRP1 TRPM3 TENM1 CRYBG3	1.95e-05	174	141	6	99eb5e1aee136c7039e23b68a43a0fa3d775859f
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL4A2 DDR2 LAMA4 MEIS1 IGDCC4 PDZRN3	2.15e-05	177	141	6	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL4A2 DDR2 LAMA4 MEIS1 IGDCC4 PDZRN3	2.15e-05	177	141	6	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL7A1 PHLDA3 LAMA4 IGDCC4 NRP1 PDZRN3	2.29e-05	179	141	6	98c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 NRP1 TRPM3 TENM1 CRYBG3	2.29e-05	179	141	6	f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	COL4A2 ADAMTS1 LAMA4 MEIS1 DCLK2 PDZRN3	2.36e-05	180	141	6	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCDC71L COL4A4 DDR2 PHLDA3 MEIS1 KIF7	2.36e-05	180	141	6	d1c52aeceb3627e3c5fb6cc3af77e0400f9380ab
ToppCell	facs-Spleen-nan-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPRIN3 ITGB2 NRP1 ARHGAP31 PKP3 AHNAK	2.52e-05	182	141	6	fbe5bdd642b86010dbef0a567b25c69c7335688f
Disease	Asperger syndrome (is_implicated_in)	DISC1 SLC25A12	2.17e-05	2	138	2	DOID:0050432 (is_implicated_in)
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	KIF7 SFTPA2 SFTPA1	1.89e-04	24	138	3	DOID:3827 (biomarker_via_orthology)
Disease	level of leukocyte immunoglobulin-like receptor subfamily B member 4 in blood serum	SFTPA2 SFTPA1	2.15e-04	5	138	2	OBA_2042200
Disease	level of prosaposin in blood serum	SFTPA2 SFTPA1	2.15e-04	5	138	2	OBA_2044552
Disease	newborn respiratory distress syndrome (biomarker_via_orthology)	SFTPA2 SFTPA1	3.22e-04	6	138	2	DOID:12716 (biomarker_via_orthology)
Disease	newborn respiratory distress syndrome (is_implicated_in)	SFTPA2 SFTPA1	4.49e-04	7	138	2	DOID:12716 (is_implicated_in)
Disease	Chloracne	ITGB2 INTS13 AHNAK	4.93e-04	33	138	3	C0263454
Disease	Malignant neoplasm of breast	KRT5 COL7A1 HK3 ADAMTS1 E2F1 CUBN HELQ MEIS1 ZNF668 BEND7 TENM1 ZFYVE26 BOD1L1 ZNHIT2	5.26e-04	1074	138	14	C0006142
Disease	procollagen galactosyltransferase 1 measurement	COL7A1 SMARCC1	5.97e-04	8	138	2	EFO_0801922
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	5.97e-04	8	138	2	DOID:0060308 (implicated_via_orthology)
Disease	leukocyte immunoglobulin-like receptor subfamily B member 4 measurement	SFTPA2 SFTPA1	5.97e-04	8	138	2	EFO_0801768
Disease	allergic rhinitis (biomarker_via_orthology)	ITGB2 MUC5AC	9.53e-04	10	138	2	DOID:4481 (biomarker_via_orthology)
Disease	albuminuria	COL4A4 CUBN FMN1 BAHCC1	1.01e-03	94	138	4	EFO_0004285
Disease	complement C1q tumor necrosis factor-related protein 1 measurement	SFTPA2 SFTPA1	1.39e-03	12	138	2	EFO_0801493
Disease	granulins measurement	SFTPA2 SFTPA1	1.39e-03	12	138	2	EFO_0008141
Disease	systolic blood pressure, alcohol consumption measurement	CCDC71L SIPA1 LINC00208	1.40e-03	47	138	3	EFO_0006335, EFO_0007878
Disease	urinary albumin to creatinine ratio	COL4A4 TSPY26P CUBN GTF3C2 BAHCC1	1.57e-03	179	138	5	EFO_0007778
Disease	Hamman-Rich syndrome	SFTPA2 SFTPA1	1.90e-03	14	138	2	C0085786
Disease	trimethylamine-N-oxide measurement	CUBN INTS13	1.90e-03	14	138	2	EFO_0010541
Disease	bacterial pneumonia (biomarker_via_orthology)	SFTPA2 SFTPA1	1.90e-03	14	138	2	DOID:874 (biomarker_via_orthology)
Disease	macula measurement	COL4A4 DLG5 E2F1 CDCP1 LRP11	1.99e-03	189	138	5	EFO_0008375
Disease	cancer biomarker measurement	FAM135B PPIP5K1	2.19e-03	15	138	2	EFO_0005127
Disease	Proteinuria	CUBN ADAMTS7	2.19e-03	15	138	2	HP_0000093
Disease	idiopathic scoliosis (implicated_via_orthology)	SSPOP KIF7	2.50e-03	16	138	2	DOID:0060250 (implicated_via_orthology)
Disease	asthma (biomarker_via_orthology)	SFTPA2 SFTPA1 MUC5AC	2.69e-03	59	138	3	DOID:2841 (biomarker_via_orthology)
Disease	Global developmental delay	ZNF142 P4HTM SLC25A12 TRPM3	3.58e-03	133	138	4	C0557874
Disease	viral load	MKRN3 ADAMTS1 CCT8L2 FBN3	3.88e-03	136	138	4	EFO_0010125
Disease	urinary microalbumin measurement	COL4A4 CUBN	3.90e-03	20	138	2	EFO_0010967
Disease	triacylglycerol 46:1 measurement	GTF3C2 NFATC1	3.90e-03	20	138	2	EFO_0010401
Disease	Familial Idiopathic Pulmonary Fibrosis	SFTPA2 SFTPA1	3.90e-03	20	138	2	C4721952
Disease	Idiopathic Pulmonary Fibrosis	SFTPA2 SFTPA1	4.30e-03	21	138	2	C1800706

Protein segments in the cluster

Peptide	Gene	Start	Entry
CVAAGGPISPGVIED	ACSM6	341	Q6P461
PSEVGGEPEIGSLCA	LINC00208	31	Q96KT6
SEDCEGLLGTEAPPR	BAHCC1	1656	Q9P281
ETGPCTLGLDRGLGE	BDP1	2211	A6H8Y1
TETGGICIAPRPSEE	ACSS1	446	Q9NUB1
ERATVTPGVEPGCAG	CNTNAP3	946	Q9BZ76
LGVDGRTCMEGSPEP	EGFL8	176	Q99944
VGEASGSCPLRPGEL	ARHGEF40	341	Q8TER5
GLSPGACSLPARVEE	ARHGEF40	1436	Q8TER5
DTCLDVIGGRDTPGA	CRYBG3	2891	Q68DQ2
GETELCMEGRGIPAP	AHSA1	296	O95433
LRQIGPGESCPDGVT	CDCP1	146	Q9H5V8
ESPENGPILGLDVGC	BCDIN3D	61	Q7Z5W3
SDEPDSCGTQGPVGV	ALPK3	551	Q96L96
GACAQVPDVEGRTPG	ALPK3	1136	Q96L96
PGSVDLLRGEPGDCG	COL4A4	1281	P53420
GPAGTPGQIDCDTDV	COL4A2	651	P08572
GPSVGVEVPDVELEC	AHNAK	1886	Q09666
RPLPGSGEGCTDDNE	FBN3	2241	Q75N90
GERGEAEGCPPSREA	DISC1	221	Q9NRI5
VPGDTVCLSVGDRVP	ATP2C1	156	P98194
CVPGADGLEAPVTEG	ADAMTS13	831	Q76LX8
ECVPVGFRPEAVDGG	ADAMTS7	526	Q9UKP4
DRELGGCELAAPGPD	IGDCC4	1181	Q8TDY8
AGLGDGEDAPVRPLC	P4HTM	36	Q9NXG6
SRCVAAPPGGKGEET	PDZRN3	231	Q9UPQ7
GTCGVVDDEPRPTGK	ADAMTS1	196	Q9UHI8
GLGREVLPPDCSSTE	FMN1	261	Q68DA7
LEDPPSISEGCGGRV	INTS13	396	Q9NVM9
SPRVVDGIEDGCGSD	KCNH3	821	Q9ULD8
LATCTPREPGVAGGD	MEIS1	96	O00470
PREPGVAGGDVCSSE	MEIS1	101	O00470
GGEGAAEPPRELRCS	NRG3	41	P56975
DCGGIDLREFPGDLP	PODN	81	Q7Z5L7
RPEAAGSPPEEGGCT	ARHGAP45	586	Q92619
ELELRAGGGPQEDCP	LRP11	76	Q86VZ4
CPEEGISAGTELRSP	MATN4	566	O95460
ERGAGLGLFCEPAPE	GFI1	146	Q99684
PSKPECGIEGETIIG	GPA33	141	Q99795
PREQEAVCPGEGTGS	GPR179	2176	Q6PRD1
ICPGEETGVPSEESG	GPR179	2241	Q6PRD1
TACTTGGELLPDPDG	MST1L	426	Q2TV78
PGEEESGCSGVVKPV	DDR2	496	Q16832
GEEAVLVCEASGVPP	HMCN2	711	Q8NDA2
GEECRLSGEGVGPVN	KRT5	476	P13647
ETGCVRPPATTDEPG	LANCL2	46	Q9NS86
PEADCLGTGAVPVER	LNX2	176	Q8N448
GGPELDRCISPEGVN	DCLK2	366	Q8N568
GVCLPGSPDVLESGV	PGPEP1L	86	A6NFU8
DPEEGFPRGLGACTL	NFATC1	216	O95644
EGLSPIESCEGLGDP	DPY19L1	141	Q2PZI1
LLPFETEVGPCGVGE	DLG5	916	Q8TDM6
PACLPGDEVGSEQRG	KIF7	581	Q2M1P5
PCGPALREGEAAAVE	METTL16	431	Q86W50
LREGEAAAVEGPCPS	METTL16	436	Q86W50
GCLEEESPLTDGLGP	IL10RA	461	Q13651
LGALPEAGPITEGCF	MUC5AC	5241	P98088
PERPVFTCGGILTGE	PCOLCE2	26	Q9UKZ9
CDVSLIPSVDGGGRG	HK3	451	P52790
LVPGDTESSVIPCGG	NUTM1	776	Q86Y26
LGCEVEAPTAGPTTP	NRP1	581	O14786
FTGPGDPDSIRCDTR	ITGB2	51	P05107
GPGKTCGPLASEEEL	PATL2	6	C9JE40
AVSGKDEVTPVPGGC	BOD1L1	1961	Q8NFC6
IGSLESPGAEGCRTP	BTBD18	511	B2RXH4
ACGDELTGEGVIRSP	CUBN	816	O60494
ELAEGSERPGPKVCG	CABIN1	1666	Q9Y6J0
GPIDVFLCPEETVGG	E2F1	291	Q01094
FLCPEETVGGISPGK	E2F1	296	Q01094
GLEPVCFERTDDIGG	FMO5	26	P49326
PCRTPEETFESGGLD	CRACR2B	106	Q8N4Y2
GLLVAEETPGSRPAC	GPAT2	626	Q6NUI2
ELPEGCQGLAPGTEV	IL12RB1	266	P42701
SEPLGEVAPRCRGAD	MARCHF11	66	A6NNE9
GGTPVRTCAGEDRPE	KRBOX4	71	Q5JUW0
ERLDGIALPPTGACG	BEND7	401	Q8N7W2
VAPGPCFGGRTLEEI	CCDC71L	166	Q8N9Z2
CTTAGGVPVTRPPDD	COL7A1	216	Q02388
PDTEGGTCIRPIAGD	CCDC168	5241	Q8NDH2
CLPDGRTENTPGVET	FAM135B	861	Q49AJ0
SPECLVLGGGDTNPD	HELQ	71	Q8TDG4
CGGLPPVEEGDRKIS	CCDC192	206	P0DO97
RSPGEPQETCSGTEV	C1orf127	441	Q8N9H9
VGGPEGERQGAICDS	GPRIN3	216	Q6ZVF9
VDVARLPECGSGDGS	POLRMT	86	O00411
CPGVAPEVTEGAKGL	NLRP6	586	P59044
SCRPLKGEPGVGFEE	NEURL4	1446	Q96JN8
ERATVTPGVEPGCAG	CNTNAP3B	946	Q96NU0
LPDAPLVCVRTDGEG	IRGQ	321	Q8WZA9
ACGRLSGVPEAEQGP	LRRC74B	21	Q6ZQY2
GDPGVQGLPLCSEDS	PCARE	336	A6NGG8
VTGECLEEGFEPPTG	LAMA4	251	Q16363
EPVVLGEEGCGFPST	INCA1	146	Q0VD86
APPGTIRGDFCIEVG	NME3	116	Q13232
SCPEGLRLVGSEVGD	IRF3	221	Q14653
PAGIPECGTDALRFG	VARS1	911	P26640
GVRQCPDGSDEGPDA	SSPOP	1626	A2VEC9
DCPGAEGSTVEPVTG	SSPOP	3866	A2VEC9
TCTRPPSEQEGAVGG	RECQL4	856	O94761
GEELLVSECEGGSPP	SMG1	1891	Q96Q15
DDGCTVVEEPRAGGL	SNX33	121	Q8WV41
GAQASGPEGIEVPCL	SIPA1	596	Q96FS4
FGGSCPERGTIVPEL	TENM1	996	Q9UKZ4
GEDPETAAVGCRGPT	SAMD11	471	Q96NU1
ERVGVCALPGGTLED	CCT8L2	201	Q96SF2
LRQAAECGPEPGVSG	RDH14	91	Q9HBH5
ECGPEPGVSGVGELI	RDH14	96	Q9HBH5
PGAVGPEDVALCSSR	SCRIB	1601	Q14160
EVKDVCVGSPGIPGT	SFTPA2	21	Q8IWL1
EDVGVTCTGPPGLDS	SSC5D	561	A1L4H1
LRDQGEGGDLPSCPT	SANBR	466	Q6NSI8
GLESSCIAGTGPDEP	SMARCC1	756	Q92922
PRGCAEGVAAALTPE	PLA2R1	16	Q13018
EVKDVCVGSPGIPGT	SFTPA1	21	Q8IWL2
PGDGERTDCEPVGLE	SAFB	301	Q15424
VTEGGGEIDFRCPLE	PHLDA3	76	Q9Y5J5
AEILPGPLEGTRCGE	TET1	211	Q8NFU7
DGSVPLPAEVLAGGC	SLC25A12	421	O75746
PGREPGFVCVDVGLS	RNF223	151	E7ERA6
RDLAGAPPGEVVGCF	PKP3	556	Q9Y446
ECTARGASLEDPRGP	SLC49A3	491	Q6UXD7
RCEQVALSSGPPEGA	nan	31	Q9BRP9
DPGPCVLGQERFTSG	TRIM11	326	Q96F44
CQDAGVREAPGPLEG	ZNF668	486	Q96K58
EGGVPEPRPGSCITD	SEMA4G	366	Q9NTN9
EAAREGVSGPDLPVC	MKRN3	21	Q13064
KGTLEGDVCGVEPPG	PBXIP1	81	Q96AQ6
PVPVVVCDGSGRASD	TRPM3	381	Q9HCF6
SRGSEESPPCEILSG	SLMAP	86	Q14BN4
GLRDLEVTCDPDSGG	TNKS1BP1	1316	Q9C0C2
LCEDPSGAGVPRTLE	TRPV2	721	Q9Y5S1
VEPGEVGGPCTRALA	YJEFN3	201	A6XGL0
DSGGPLVCEEPSGRF	TMPRSS9	386	Q7Z410
PGSCSVGELPEREGQ	PRRT4	321	C9JH25
GKGCGFPSPTREVEI	ARHGAP31	856	Q2M1Z3
GDGERTDCEPVGLEP	SAFB2	301	Q14151
GGEALPSGSECEVPL	VASN	641	Q6EMK4
AAERVLGDVPGACTP	ZNHIT2	176	Q9UHR6
TTPIEETGGEGCPAV	TNFRSF12A	111	Q9NP84
EIDDSEFCIRIPGGG	PSMG2	171	Q969U7
AACPGGEEVDGAPRD	GTF3C2	231	Q8WUA4
PGCLLVEATATEEGP	ZNF142	56	P52746
ELCALTGPFERGEPA	LCMT2	131	O60294
GGTPVRTCAGEDRPE	ZNF674	71	Q2M3X9
DEAPETCGAEGLGTR	TSPY26P	76	Q9H489
EEVPGTRVTGGQPAC	TG	1196	P01266
SESVEEKGGGPPRCS	ZFYVE26	1046	Q68DK2
VEEEGSAPAGCGFRP	PPIP5K1	916	Q6PFW1
CGVGDPAEEGRGETA	ZNF784	301	Q8NCA9
EGEECRLSGEGVSPV	KRT75	456	O95678
PGGPGAVAEEERCTV	JMJD8	31	Q96S16