Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein propionyltransferase activity	KAT8 EP300	4.27e-05	2	131	2	GO:0061920
GeneOntologyMolecularFunction	calcium ion binding	PITPNM2 FAT3 CUBN CBLB PCDH20 SVEP1 CRB1 MICU3 CELSR2 HMCN1 VCAN JAG1 NCAN HABP2 LTBP3	1.20e-04	749	131	15	GO:0005509
Domain	EGF_CA	FAT3 CUBN SVEP1 CRB1 CELSR2 HMCN1 VCAN JAG1 NCAN HABP2 LTBP3	7.47e-10	122	128	11	SM00179
Domain	EGF-like_Ca-bd_dom	FAT3 CUBN SVEP1 CRB1 CELSR2 HMCN1 VCAN JAG1 NCAN HABP2 LTBP3	8.90e-10	124	128	11	IPR001881
Domain	ASX_HYDROXYL	FAT3 CUBN SVEP1 CRB1 CELSR2 HMCN1 VCAN JAG1 NCAN LTBP3	1.65e-09	100	128	10	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT3 CUBN SVEP1 CRB1 CELSR2 HMCN1 VCAN JAG1 NCAN LTBP3	2.93e-09	106	128	10	IPR000152
Domain	EGF_Ca-bd_CS	FAT3 CUBN SVEP1 CRB1 HMCN1 VCAN JAG1 NCAN LTBP3	2.16e-08	97	128	9	IPR018097
Domain	EGF_1	FAT3 LAMA4 CUBN ITGB4 SVEP1 CRB1 CELSR2 HMCN1 VCAN JAG1 NCAN HABP2 LTBP3	2.22e-08	255	128	13	PS00022
Domain	EGF_CA	FAT3 CUBN SVEP1 CRB1 HMCN1 VCAN JAG1 NCAN LTBP3	2.59e-08	99	128	9	PS01187
Domain	EGF-like_CS	FAT3 LAMA4 CUBN ITGB4 SVEP1 CRB1 CELSR2 HMCN1 VCAN JAG1 NCAN HABP2 LTBP3	2.92e-08	261	128	13	IPR013032
Domain	Sushi	CFH CR1 SEZ6L2 SVEP1 VCAN NCAN CSMD1	6.23e-08	52	128	7	PF00084
Domain	EGF	FAT3 LAMA4 CUBN SVEP1 CRB1 CELSR2 HMCN1 VCAN JAG1 NCAN HABP2 LTBP3	7.80e-08	235	128	12	SM00181
Domain	CCP	CFH CR1 SEZ6L2 SVEP1 VCAN NCAN CSMD1	8.16e-08	54	128	7	SM00032
Domain	SUSHI	CFH CR1 SEZ6L2 SVEP1 VCAN NCAN CSMD1	1.06e-07	56	128	7	PS50923
Domain	Sushi_SCR_CCP_dom	CFH CR1 SEZ6L2 SVEP1 VCAN NCAN CSMD1	1.20e-07	57	128	7	IPR000436
Domain	EGF-like_dom	FAT3 LAMA4 CUBN SVEP1 CRB1 CELSR2 HMCN1 VCAN JAG1 NCAN HABP2 LTBP3	1.46e-07	249	128	12	IPR000742
Domain	EGF	CUBN SVEP1 CRB1 CELSR2 HMCN1 VCAN JAG1 NCAN HABP2	2.11e-07	126	128	9	PF00008
Domain	EGF_2	FAT3 CUBN ITGB4 SVEP1 CRB1 CELSR2 HMCN1 VCAN JAG1 NCAN HABP2 LTBP3	2.86e-07	265	128	12	PS01186
Domain	EGF_3	FAT3 CUBN SVEP1 CRB1 CELSR2 HMCN1 VCAN JAG1 NCAN HABP2 LTBP3	6.62e-07	235	128	11	PS50026
Domain	hEGF	SVEP1 CRB1 CELSR2 JAG1 LTBP3	1.21e-06	28	128	5	PF12661
Domain	EGF_CA	FAT3 CUBN SVEP1 HMCN1 JAG1 LTBP3	2.77e-05	86	128	6	PF07645
Domain	Coatomer_g_Cpla	COPG1 COPG2	4.66e-05	2	128	2	IPR032154
Domain	-	COPG1 COPG2	4.66e-05	2	128	2	2.60.40.1480
Domain	AlaDh_PNT_C	AASS NNT	4.66e-05	2	128	2	PF01262
Domain	AlaDH/PNT_N	AASS NNT	4.66e-05	2	128	2	IPR007886
Domain	Sacchrp_dh_NADP	SCCPDH AASS	4.66e-05	2	128	2	PF03435
Domain	COP-gamma_platf	COPG1 COPG2	4.66e-05	2	128	2	PF08752
Domain	Coatomer_g_Cpla	COPG1 COPG2	4.66e-05	2	128	2	PF16381
Domain	Coatomer_gsu_app_Ig-like-sub	COPG1 COPG2	4.66e-05	2	128	2	IPR013040
Domain	AlaDh_PNT_N	AASS NNT	4.66e-05	2	128	2	PF05222
Domain	AlaDh_PNT_N	AASS NNT	4.66e-05	2	128	2	SM01003
Domain	AlaDh_PNT_C	AASS NNT	4.66e-05	2	128	2	SM01002
Domain	Sacchrp_dh_NADP	SCCPDH AASS	4.66e-05	2	128	2	IPR005097
Domain	ALADH_PNT_1	AASS NNT	4.66e-05	2	128	2	PS00836
Domain	ALADH_PNT_2	AASS NNT	4.66e-05	2	128	2	PS00837
Domain	AlaDH/PNT_NAD(H)-bd	AASS NNT	4.66e-05	2	128	2	IPR007698
Domain	Coatomer_gsu	COPG1 COPG2	4.66e-05	2	128	2	IPR017106
Domain	-	FAT3 LAMA4 SVEP1 CRB1 LMAN2L CELSR2	4.86e-05	95	128	6	2.60.120.200
Domain	Growth_fac_rcpt_	CUBN SVEP1 CRB1 CELSR2 HMCN1 JAG1 LTBP3	1.01e-04	156	128	7	IPR009030
Domain	LAM_G_DOMAIN	FAT3 LAMA4 CRB1 CELSR2	1.30e-04	38	128	4	PS50025
Domain	ConA-like_dom	TMPRSS15 FAT3 LAMA4 ITGB4 SVEP1 CRB1 LMAN2L CELSR2	1.35e-04	219	128	8	IPR013320
Domain	Laminin_G_2	FAT3 LAMA4 CRB1 CELSR2	1.59e-04	40	128	4	PF02210
Domain	-	DHRS11 DHRS13 SCCPDH KCNU1 AASS HSD3B2 NNT	1.66e-04	169	128	7	3.40.50.720
Domain	NAD(P)-bd_dom	DHRS11 DHRS13 SCCPDH KCNU1 AASS HSD3B2 NNT	1.91e-04	173	128	7	IPR016040
Domain	LamG	FAT3 LAMA4 CRB1 CELSR2	2.31e-04	44	128	4	SM00282
Domain	Clathrin_a/coatomer_app_sub_C	COPG1 COPG2	2.77e-04	4	128	2	IPR015873
Domain	-	COPG1 COPG2	2.77e-04	4	128	2	3.30.310.30
Domain	CUB	TMPRSS15 CUBN SEZ6L2 CSMD1	3.51e-04	49	128	4	PF00431
Domain	CUB	TMPRSS15 CUBN SEZ6L2 CSMD1	3.80e-04	50	128	4	SM00042
Domain	-	TMPRSS15 CUBN SEZ6L2 CSMD1	4.42e-04	52	128	4	2.60.120.290
Domain	SMC	SMC1A SMC1B	4.60e-04	5	128	2	IPR024704
Domain	PLPL	PNPLA2 PNPLA1	4.60e-04	5	128	2	IPR033562
Domain	CUB	TMPRSS15 CUBN SEZ6L2 CSMD1	4.75e-04	53	128	4	PS01180
Domain	VWF_A	VWA5B2 ITGB4 SVEP1 HMCN1 CPNE3	5.98e-04	99	128	5	IPR002035
Domain	CUB_dom	TMPRSS15 CUBN SEZ6L2 CSMD1	6.28e-04	57	128	4	IPR000859
Domain	Laminin_G	FAT3 LAMA4 CRB1 CELSR2	6.71e-04	58	128	4	IPR001791
Domain	SMC_hinge	SMC1A SMC1B	6.87e-04	6	128	2	SM00968
Domain	Acid_Pase_AS	ACP6 PPIP5K1	6.87e-04	6	128	2	IPR033379
Domain	SMC_hinge	SMC1A SMC1B	6.87e-04	6	128	2	PF06470
Domain	SMC_hinge	SMC1A SMC1B	6.87e-04	6	128	2	IPR010935
Domain	HIS_ACID_PHOSPHAT_2	ACP6 PPIP5K1	9.57e-04	7	128	2	PS00778
Domain	HIS_ACID_PHOSPHAT_1	ACP6 PPIP5K1	9.57e-04	7	128	2	PS00616
Domain	His_Pase_clade-2	ACP6 PPIP5K1	1.27e-03	8	128	2	IPR000560
Domain	Coatomer/calthrin_app_sub_C	COPG1 COPG2	1.27e-03	8	128	2	IPR009028
Domain	His_Phos_2	ACP6 PPIP5K1	1.27e-03	8	128	2	PF00328
Domain	RecF/RecN/SMC_N	SMC1A SMC1B	1.27e-03	8	128	2	IPR003395
Domain	SMC_N	SMC1A SMC1B	1.27e-03	8	128	2	PF02463
Domain	Patatin	PNPLA2 PNPLA1	1.63e-03	9	128	2	PF01734
Domain	PNPLA	PNPLA2 PNPLA1	1.63e-03	9	128	2	PS51635
Domain	Patatin/PLipase_A2-rel	PNPLA2 PNPLA1	1.63e-03	9	128	2	IPR002641
Domain	VWFA	ITGB4 SVEP1 HMCN1 CPNE3	2.44e-03	82	128	4	PS50234
Domain	GFP-like	SVEP1 HMCN1	2.46e-03	11	128	2	IPR023413
Domain	Frizzled	FZD7 SMO	2.46e-03	11	128	2	IPR000539
Domain	Frizzled	FZD7 SMO	2.46e-03	11	128	2	PF01534
Domain	-	SVEP1 HMCN1	2.46e-03	11	128	2	2.40.155.10
Domain	Frizzled	FZD7 SMO	2.46e-03	11	128	2	SM01330
Domain	VWA	ITGB4 SVEP1 HMCN1 CPNE3	2.66e-03	84	128	4	SM00327
Domain	Coatomer/clathrin_app_Ig-like	COPG1 COPG2	2.94e-03	12	128	2	IPR013041
Domain	Link_dom	VCAN NCAN	3.46e-03	13	128	2	IPR000538
Domain	Xlink	VCAN NCAN	3.46e-03	13	128	2	PF00193
Domain	OTU	YOD1 VCPIP1	3.46e-03	13	128	2	PF02338
Domain	Carboxylesterase_B_CS	CES4A NLGN2	3.46e-03	13	128	2	IPR019819
Domain	LINK_2	VCAN NCAN	3.46e-03	13	128	2	PS50963
Domain	LINK	VCAN NCAN	3.46e-03	13	128	2	SM00445
Domain	LINK_1	VCAN NCAN	3.46e-03	13	128	2	PS01241
Domain	CARBOXYLESTERASE_B_2	CES4A NLGN2	4.02e-03	14	128	2	PS00941
Domain	COesterase	CES4A NLGN2	4.02e-03	14	128	2	PF00135
Domain	CarbesteraseB	CES4A NLGN2	4.02e-03	14	128	2	IPR002018
Domain	OTU	YOD1 VCPIP1	4.62e-03	15	128	2	PS50802
Domain	Clathrin/coatomer_adapt-like_N	COPG1 COPG2	4.62e-03	15	128	2	IPR002553
Domain	Adaptin_N	COPG1 COPG2	4.62e-03	15	128	2	PF01602
Domain	OTU_dom	YOD1 VCPIP1	4.62e-03	15	128	2	IPR003323
Domain	fn3	SDK2 DCC ITGB4 TYRO3 IL6ST	5.19e-03	162	128	5	PF00041
Domain	Frizzled/SFRP	FZD7 SMO	5.25e-03	16	128	2	IPR015526
Domain	Acyl_Trfase/lysoPLipase	PNPLA2 PNPLA1	5.93e-03	17	128	2	IPR016035
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ALKBH4 VWA5B2 PITPNM2 PHLDB3 PNPLA2 SH3RF1 ITGA3 ITGB4 FZD7 NCOR1 DIP2A IGF2R LMAN2L CELSR2 TULP4 SLC25A39 FLCN CACNA1H NLGN2 WDR90 LTBP3 LTK ZC3H7B SUFU EP300	8.94e-13	1105	134	25	35748872
Pubmed	Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.	ADAMTS9 VCAN SMO HABP2	1.76e-06	23	134	4	30814516
Pubmed	Myocardial Angiopoietin-1 Controls Atrial Chamber Morphogenesis by Spatiotemporal Degradation of Cardiac Jelly.	BMP10 ADAMTS9 VCAN JAG1	2.11e-06	24	134	4	29791855
Pubmed	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	MCHR1 MYOD1 FZD7 IGF2R EGR2 JAG1 SMO HSD3B2 LTBP3 IL6ST	2.54e-06	383	134	10	19453261
Pubmed	Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.	ADAMTS9 VCAN JAG1	4.62e-06	9	134	3	23095891
Pubmed	Expression screening of a yeast artificial chromosome contig refines the location of the mouse H3a minor histocompatibility antigen gene.	TYRO3 LTK NNT	6.58e-06	10	134	3	9670959
Pubmed	Human ALKBH4 interacts with proteins associated with transcription.	ALKBH4 ZFHX3 EP300	6.58e-06	10	134	3	23145062
Pubmed	Analysis of Netrin 1 receptors during inner ear development.	ITGA3 DCC ITGB4	9.02e-06	11	134	3	17616930
Pubmed	Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development.	SALL3 BMP10 VCAN JAG1	1.13e-05	36	134	4	29891551
Pubmed	Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis.	LAMA4 ITGA3 ITGB4	1.20e-05	12	134	3	11381080
Pubmed	Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles.	LAMA4 ITGA3 ITGB4	1.20e-05	12	134	3	12843252
Pubmed	Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis.	BMP10 ADAMTS9 VCAN ADAMTS18	1.40e-05	38	134	4	18267097
Pubmed	Diagnostic value of integrin alpha3, beta4, and beta5 gene expression levels for the clinical outcome of tongue squamous cell carcinoma.	ITGA3 ITGB4	1.47e-05	2	134	2	18224668
Pubmed	Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development.	ITGA3 ITGB4	1.47e-05	2	134	2	11784011
Pubmed	Assignment of complement components C4 binding protein (C4BP) and factor H (FH) to human chromosome 1q, using cDNA probes.	CFH CR1	1.47e-05	2	134	2	2977721
Pubmed	SMC1α Substitutes for Many Meiotic Functions of SMC1β but Cannot Protect Telomeres from Damage.	SMC1A SMC1B	1.47e-05	2	134	2	29337080
Pubmed	ITGA3 and ITGB4 expression biomarkers estimate the risks of locoregional and hematogenous dissemination of oral squamous cell carcinoma.	ITGA3 ITGB4	1.47e-05	2	134	2	24006899
Pubmed	Polymorphisms in Complement Factor H and Hemicentin-1 genes in a Japanese population with dry-type age-related macular degeneration.	CFH HMCN1	1.47e-05	2	134	2	17157600
Pubmed	Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes.	CFH HMCN1	1.47e-05	2	134	2	17591627
Pubmed	Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma.	SMO SUFU	1.47e-05	2	134	2	30206138
Pubmed	Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.	LCAT CELSR2 ZFHX3 CSMD1	1.56e-05	39	134	4	21347282
Pubmed	Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation.	SMC1A EP300 SMC1B	1.97e-05	14	134	3	21875947
Pubmed	Biological insights from 108 schizophrenia-associated genetic loci.	PITPNM2 NAGA MSANTD2 LCAT SEZ6L2 NCAN CSMD1 EP300	2.44e-05	303	134	8	25056061
Pubmed	Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression.	ITGA3 ITGB4 JAG1	3.02e-05	16	134	3	17021047
Pubmed	The orphan nuclear receptor, COUP-TF II, inhibits myogenesis by post-transcriptional regulation of MyoD function: COUP-TF II directly interacts with p300 and myoD.	MYOD1 EP300	4.41e-05	3	134	2	9826778
Pubmed	MyoD stimulates RB promoter activity via the CREB/p300 nuclear transduction pathway.	MYOD1 EP300	4.41e-05	3	134	2	12665587
Pubmed	Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.	BBS1 CRB1	4.41e-05	3	134	2	26216965
Pubmed	Expression of ERβ and its co-regulators p300 and NCoR in human transitional cell bladder cancer.	NCOR1 EP300	4.41e-05	3	134	2	21525722
Pubmed	Exogenous expression of a dominant negative RORalpha1 vector in muscle cells impairs differentiation: RORalpha1 directly interacts with p300 and myoD.	MYOD1 EP300	4.41e-05	3	134	2	9862959
Pubmed	Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus.	COPG1 COPG2	4.41e-05	3	134	2	11893085
Pubmed	FHL3 differentially regulates the expression of MyHC isoforms through interactions with MyoD and pCREB.	MYOD1 FHL3	4.41e-05	3	134	2	26499038
Pubmed	Novel meiosis-specific isoform of mammalian SMC1.	SMC1A SMC1B	4.41e-05	3	134	2	11564881
Pubmed	A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.	CFH CR1	4.41e-05	3	134	2	3782802
Pubmed	Analysis of variants in the complement factor H, the elongation of very long chain fatty acids-like 4 and the hemicentin 1 genes of age-related macular degeneration in the Finnish population.	CFH HMCN1	4.41e-05	3	134	2	16885922
Pubmed	Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytes.	CFH CR1	4.41e-05	3	134	2	20702729
Pubmed	Identification and recombinant production of human laminin alpha4 subunit splice variants.	LAMA4 ITGA3	4.41e-05	3	134	2	12445830
Pubmed	Identification of residues within the 727-767 segment of human complement component C3 important for its interaction with factor H and with complement receptor 1 (CR1, CD35).	CFH CR1	4.41e-05	3	134	2	9988761
Pubmed	The nuclear receptor corepressor N-CoR regulates differentiation: N-CoR directly interacts with MyoD.	MYOD1 NCOR1	4.41e-05	3	134	2	10406466
Pubmed	Promoter-bound p300 complexes facilitate post-mitotic transmission of transcriptional memory.	SMC1A EP300	4.41e-05	3	134	2	24945803
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	KIF23 COPG1 RNF213 COPG2 MCCC2 USP19 CRB1 NCOR1 IGF2R ZFHX3 MARVELD2 TARS1	4.99e-05	777	134	12	35844135
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	CFH B4GAT1 NAGA LAMA4 RNF213 ITGA3 SEZ6L2 ITGB4 USP19 IGF2R LMAN2L CELSR2 FLCN LTBP3 IL6ST	6.39e-05	1201	134	15	35696571
Pubmed	PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development.	BMP10 ADAMTS9 VCAN JAG1	8.14e-05	59	134	4	38374152
Pubmed	β1 integrins regulate cellular behaviour and cardiomyocyte organization during ventricular wall formation.	BMP10 VCAN HABP2	8.16e-05	22	134	3	38794925
Pubmed	PML-retinoic acid receptor alpha inhibits PML IV enhancement of PU.1-induced C/EBPepsilon expression in myeloid differentiation.	CEBPE EP300	8.80e-05	4	134	2	17562868
Pubmed	Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury.	CFH CR1	8.80e-05	4	134	2	27165610
Pubmed	Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C.	MYOD1 EP300	8.80e-05	4	134	2	9001254
Pubmed	Differential roles of p300 and PCAF acetyltransferases in muscle differentiation.	MYOD1 EP300	8.80e-05	4	134	2	9659901
Pubmed	Identification of signature genes for detecting hedgehog pathway activation in esophageal cancer.	SMO SUFU	8.80e-05	4	134	2	21210262
Pubmed	Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes.	ITGA3 ITGB4	8.80e-05	4	134	2	16707493
Pubmed	Interaction between acetylated MyoD and the bromodomain of CBP and/or p300.	MYOD1 EP300	8.80e-05	4	134	2	11463815
Pubmed	CREB-binding protein/p300 activates MyoD by acetylation.	MYOD1 EP300	8.80e-05	4	134	2	10944526
Pubmed	Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus.	TYRO3 LTK	8.80e-05	4	134	2	14695357
Pubmed	Expression of laminin-5 and integrins in actinic cheilitis and superficially invasive squamous cell carcinomas of the lip.	ITGA3 ITGB4	8.80e-05	4	134	2	22917688
Pubmed	Direct association between the CREB-binding protein (CBP) and nuclear receptor corepressor (N-CoR).	NCOR1 EP300	8.80e-05	4	134	2	17073437
Pubmed	Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.	ADAMTS9 ADAMTS18	8.80e-05	4	134	2	16507336
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-7 ERVK-24	8.80e-05	4	134	2	10469592
Pubmed	Receptor tyrosine kinase gene Tyro3 maps to mouse chromosome 2, closely linked to Ltk.	TYRO3 LTK	8.80e-05	4	134	2	8661736
Pubmed	Divergence of hedgehog signal transduction mechanism between Drosophila and mammals.	SMO SUFU	8.80e-05	4	134	2	16459297
Pubmed	Suppression of Hedgehog signaling is required for cementum apposition.	SMO SUFU	8.80e-05	4	134	2	32350360
Pubmed	Activation of the beta myosin heavy chain promoter by MEF-2D, MyoD, p300, and the calcineurin/NFATc1 pathway.	MYOD1 EP300	8.80e-05	4	134	2	17111365
Pubmed	Epithelial development and differentiation in the mammary gland is not dependent on alpha 3 or alpha 6 integrin subunits.	ITGA3 ITGB4	8.80e-05	4	134	2	11336507
Pubmed	Biosynthesis and expression of a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats-15: a novel versican-cleaving proteoglycanase.	ADAMTS9 VCAN	8.80e-05	4	134	2	24220035
Pubmed	Distinct Roles of Meiosis-Specific Cohesin Complexes in Mammalian Spermatogenesis.	SMC1A SMC1B	8.80e-05	4	134	2	27792785
Pubmed	Lecticans: organizers of the brain extracellular matrix.	VCAN NCAN	8.80e-05	4	134	2	10766023
Pubmed	ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation.	ADAMTS9 VCAN HABP2	9.36e-05	23	134	3	26027930
Pubmed	Analysis of BCL6-interacting proteins by tandem mass spectrometry.	KIF13B NCOR1 SMO CSMD1	9.88e-05	62	134	4	16147992
Pubmed	Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes.	EGR2 VCAN NCAN	1.07e-04	24	134	3	25344368
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	LAMA4 HMCN1 ADAMTS9 VCAN	1.12e-04	64	134	4	22261194
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	ACP6 FCRL2 SLC29A3 DHRS11 DHRS13 B3GNT3 PNKD SLC44A4 SEZ6L2 LMAN2L CES4A CSMD1 SUFU	1.17e-04	985	134	13	12975309
Pubmed	Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.	IGF2R ADAMTS9 VCAN	1.21e-04	25	134	3	29475039
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	VCAN JAG1 ADAMTS18	1.36e-04	26	134	3	34189436
Pubmed	Deletion of Crry and DAF on murine platelets stimulates thrombopoiesis and increases factor H-dependent resistance of peripheral platelets to complement attack.	CFH CR1	1.46e-04	5	134	2	23390291
Pubmed	Human p300 protein is a coactivator for the transcription factor MyoD.	MYOD1 EP300	1.46e-04	5	134	2	8621548
Pubmed	Identification and molecular characterization of the mammalian α-kleisin RAD21L.	SMC1A SMC1B	1.46e-04	5	134	2	21527826
Pubmed	C3-dependent mechanism of microglial priming relevant to multiple sclerosis.	CFH CR1	1.46e-04	5	134	2	22219359
Pubmed	Partial rescue of epithelial phenotype in integrin beta4 null mice by a keratin-5 promoter driven human integrin beta4 transgene.	ITGA3 ITGB4	1.46e-04	5	134	2	10547352
Pubmed	Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain.	VCAN NCAN	1.46e-04	5	134	2	9716537
Pubmed	Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations.	FZD7 IL6ST	1.46e-04	5	134	2	30622113
Pubmed	Association between polymorphisms of microRNA-binding sites in integrin genes and gastric cancer in Chinese Han population.	ITGA3 ITGB4	1.46e-04	5	134	2	25472585
Pubmed	The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells.	CFH CR1	1.46e-04	5	134	2	20675597
Pubmed	Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.	CFH CR1	1.46e-04	5	134	2	20962256
Pubmed	Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication.	KAT8 EP300	1.46e-04	5	134	2	17182677
Pubmed	Involvement of MyoD and c-myb in regulation of basal and estrogen-induced transcription activity of the BRCA1 gene.	MYOD1 EP300	1.46e-04	5	134	2	20364308
Pubmed	The opposing roles of laminin-binding integrins in cancer.	ITGA3 ITGB4	1.46e-04	5	134	2	27562932
Pubmed	The small chromatin-binding protein p8 coordinates the association of anti-proliferative and pro-myogenic proteins at the myogenin promoter.	MYOD1 EP300	1.46e-04	5	134	2	19723804
Pubmed	Identification of nuclear receptor corepressor as a peroxisome proliferator-activated receptor alpha interacting protein.	NCOR1 EP300	1.46e-04	5	134	2	10336495
Pubmed	The LIM-only protein DRAL/FHL2 interacts with and is a corepressor for the promyelocytic leukemia zinc finger protein.	MYOD1 FHL3	1.46e-04	5	134	2	12145280
Pubmed	Genetic variance in the adiponutrin gene family and childhood obesity.	PNPLA2 PNPLA1	1.46e-04	5	134	2	19390624
Pubmed	Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators.	SMC1A SMC1B	1.46e-04	5	134	2	18219272
Pubmed	Differential expression of alpha 3 and alpha 6 integrins in the developing mouse inner ear.	ITGA3 ITGB4	1.46e-04	5	134	2	11891657
Pubmed	Temporally and spatially selective loss of Rec8 protein from meiotic chromosomes during mammalian meiosis.	SMC1A SMC1B	1.46e-04	5	134	2	12759374
Pubmed	Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts.	SMO SUFU	1.46e-04	5	134	2	18488998
Pubmed	Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300.	NCOR1 EP300	1.46e-04	5	134	2	14985122
Pubmed	Spatiotemporal regulation of GLI target genes in the mammalian limb bud.	SDK2 SALL3 SVEP1 FZD7 JAG1 SMO	1.58e-04	207	134	6	26238476
Pubmed	A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.	SDK2 SH3RF1 LAMA4 FZD7 YOD1 SASS6 HABP2	1.78e-04	302	134	7	30561431
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	CUBN HMCN1 ADAMTS9 ADAMTS18	2.07e-04	75	134	4	20637190
Pubmed	A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis.	NCOR1 IL6ST	2.19e-04	6	134	2	15852015
Pubmed	Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest.	BRPF1 EP300	2.19e-04	6	134	2	19001415
Pubmed	Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1.	FHL3 EP300	2.19e-04	6	134	2	22219185
Pubmed	Polymorphisms in predicted microRNA-binding sites in integrin genes and breast cancer: ITGB4 as prognostic marker.	ITGA3 ITGB4	2.19e-04	6	134	2	18550570
Interaction	TOP3B interactions	ALKBH4 VWA5B2 PITPNM2 PHLDB3 PNPLA2 KIF23 CAD SH3RF1 SMC1A ITGA3 ITGB4 FZD7 NCOR1 DIP2A IGF2R LMAN2L CELSR2 TULP4 SLC25A39 FLCN CACNA1H NLGN2 WDR90 LTBP3 LTK ZC3H7B TSR3 SUFU EP300	4.63e-08	1470	130	29	int:TOP3B
Interaction	PTGES3 interactions	PHLDB3 PNPLA2 KIF23 CAD COPG1 BBS1 COPG2 DYRK4 DIP2A SCCPDH KAT8 SHPRH FLCN SIX5	9.16e-07	437	130	14	int:PTGES3
Interaction	LGALS1 interactions	KIF23 SDK2 FAT3 LAMA4 ITGA3 SEZ6L2 IGF2R CELSR2 VCAN JAG1 IL6ST	1.04e-05	332	130	11	int:LGALS1
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CFH CR1 SEZ6L2 SVEP1 VCAN NCAN CSMD1	2.52e-08	57	99	7	1179
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	VCAN NCAN	1.77e-04	4	99	2	574
GeneFamily	Structural maintenance of chromosomes proteins\|Cohesin complex	SMC1A SMC1B	6.12e-04	7	99	2	761
GeneFamily	Cohesin complex	SMC1A SMC1B	8.13e-04	8	99	2	1060
GeneFamily	Patatin like phospholipase domain containing	PNPLA2 PNPLA1	1.30e-03	10	99	2	466
GeneFamily	G protein-coupled receptors, Class F frizzled	FZD7 SMO	1.58e-03	11	99	2	286
GeneFamily	Fibronectin type III domain containing	SDK2 DCC ITGB4 TYRO3 IL6ST	1.87e-03	160	99	5	555
GeneFamily	OTU domain containing	YOD1 VCPIP1	3.83e-03	17	99	2	669
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	KAT8 EP300	3.83e-03	17	99	2	486
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS9 ADAMTS18	4.78e-03	19	99	2	50
GeneFamily	Proteases, serine	TMPRSS15 PRSS36 PRSS50	4.99e-03	63	99	3	738
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	FCRL2 ITGA3 CR1 ITGB4 IGF2R JAG1 IL6ST	5.92e-03	394	99	7	471
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	CAMK1D GPR25 SMC1A NCOR1 CELSR2 TULP4 SUFU EP300	3.78e-06	180	132	8	M8239
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_PROXIMAL_SECRETORY_3_CELL	CFH PHLDB3 CAMK1D B3GNT3 SLC44A4 SEZ6L2 ITGB4 VCAN	1.99e-05	226	132	8	M45709
Coexpression	SERVITJA_LIVER_HNF1A_TARGETS_DN	CFH CAMK1D AASS SLCO1A2 HABP2 HSD3B2 SLC23A1	2.18e-05	166	132	7	M2398
Coexpression	BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP	SMC1A LAMA4 CR1 USP19 DIP2A VCAN CPNE3 ZC3H7B TSR3 EP300	2.89e-05	389	132	10	M6520
Coexpression	LIM_MAMMARY_STEM_CELL_UP	SDK2 LCAT CBLB ITGB4 SVEP1 EGR2 VCAN JAG1 UPP1 NLGN2 IL6ST	3.22e-05	479	132	11	M2573
Coexpression	LIM_MAMMARY_STEM_CELL_UP	SDK2 LCAT CBLB ITGB4 SVEP1 EGR2 VCAN JAG1 UPP1 NLGN2 IL6ST	3.47e-05	483	132	11	MM1082
Coexpression	SERVITJA_LIVER_HNF1A_TARGETS_DN	CFH CAMK1D AASS SLCO1A2 HABP2 HSD3B2 SLC23A1	5.17e-05	190	132	7	MM1311
Coexpression	MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3	MCHR1 LAMA4 SEZ6L2 PCDH20 PRSS36 NCAN	6.70e-05	136	132	6	M2005
Coexpression	GSE557_WT_VS_CIITA_KO_DC_UP	SLC29A3 COPG2 LCAT YOD1 SLC25A39 LTK SUFU	7.15e-05	200	132	7	M6006
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_200	FAT3 RNF213 HMCN1 EGR2 ADAMTS9 VCAN HSD3B2 C1QTNF7	2.29e-06	138	131	8	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_200
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500	CFH FAT3 RNF213 SVEP1 HMCN1 EGR2 ADAMTS9 VCAN JAG1 HSD3B2 C1QTNF7	1.33e-05	356	131	11	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 DCC ADCY8 SVEP1 CRB1 HMCN1 AASS HSD3B2	2.72e-08	160	132	8	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 DCC ADCY8 SVEP1 CRB1 HMCN1 AASS HSD3B2	2.72e-08	160	132	8	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CFH SDK2 FAT3 LAMA4 SVEP1 HMCN1 AASS C1QTNF7	1.52e-07	200	132	8	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CFH SDK2 FAT3 LAMA4 SVEP1 HMCN1 AASS C1QTNF7	1.52e-07	200	132	8	a510deaada669e690329183e18df02870bd204b3
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFH SDK2 FAT3 LAMA4 SVEP1 HMCN1 AASS C1QTNF7	1.52e-07	200	132	8	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3\|E16.5-samps / Age Group, Lineage, Cell class and subclass	DHRS11 SVEP1 IGF2R VCAN WDR90 C1QTNF7 UHRF2	3.16e-07	149	132	7	651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCell	10x5'-Lung-Lymphocytic_Invariant-Inducer-like-ILC3\|Lung / Manually curated celltypes from each tissue	ALKBH4 MSANTD2 BBS1 LMAN2L AASS ANKAR NNT	1.46e-06	187	132	7	0e7aa481effdd8c2fbdf8b65852821dec2d92cde
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFH SALL3 ITGB4 HMCN1 ADAMTS9 CSMD1 IL6ST	1.56e-06	189	132	7	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	CFH SALL3 MCHR1 ITGB4 HMCN1 VCAN IL6ST	1.74e-06	192	132	7	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMPRSS15 FAT3 DCC SVEP1 NLGN2 C1QTNF7	2.00e-06	125	132	6	b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCell	368C-Fibroblasts-Fibroblast-G\|368C / Donor, Lineage, Cell class and subclass (all cells)	CFH FAT3 LAMA4 SVEP1 HMCN1 C1QTNF7 IL6ST	2.06e-06	197	132	7	156155c2f0c1a2461e45803da578af18ee221660
ToppCell	368C-Fibroblasts-Fibroblast-G-\|368C / Donor, Lineage, Cell class and subclass (all cells)	CFH FAT3 LAMA4 SVEP1 HMCN1 C1QTNF7 IL6ST	2.06e-06	197	132	7	d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH FAT3 LAMA4 SVEP1 HMCN1 AASS C1QTNF7	2.13e-06	198	132	7	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH FAT3 LAMA4 SVEP1 HMCN1 AASS C1QTNF7	2.20e-06	199	132	7	66a79732caf2f04c09b4d9832377aa01ca477677
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH FAT3 LAMA4 SVEP1 HMCN1 VCAN C1QTNF7	2.28e-06	200	132	7	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH FAT3 LAMA4 SVEP1 HMCN1 VCAN C1QTNF7	2.28e-06	200	132	7	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH FAT3 LAMA4 SVEP1 HMCN1 VCAN C1QTNF7	2.28e-06	200	132	7	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Substantia_nigra-Macroglia-CSF_related\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	DYRK4 LRRC43 ADAM5 CFAP70 DNAH6 SMC1B	3.27e-06	136	132	6	47663c5d81c766a333207a44fc5b58b07309ee76
ToppCell	Substantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	DYRK4 LRRC43 ADAM5 CFAP70 DNAH6 SMC1B	3.27e-06	136	132	6	6d2e5b871f4cf8d64e6fe0be666fb3490797c635
ToppCell	Substantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	DYRK4 LRRC43 ADAM5 CFAP70 DNAH6 SMC1B	3.27e-06	136	132	6	fd4269d194c7c11c6ab4383393a01efab05cbace
ToppCell	Substantia_nigra-Macroglia-CSF_related-EPENDYMAL\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	DYRK4 LRRC43 ADAM5 CFAP70 DNAH6 SMC1B	3.27e-06	136	132	6	3f6cec8d52c84191f7f6e2dd4dc47524dfd5b21b
ToppCell	Substantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	DYRK4 LRRC43 ADAM5 CFAP70 DNAH6 SMC1B	3.27e-06	136	132	6	67d736096d6b6ddb4722809557f5e987063b8d23
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	FAT3 ITGA3 ADAMTS9 JAG1 ZFHX3 CACNA1H	8.33e-06	160	132	6	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	FAT3 ITGA3 ADAMTS9 JAG1 ZFHX3 CACNA1H	8.63e-06	161	132	6	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	Adult-Mesenchymal-chondrocyte-D231\|Adult / Lineage, Cell type, age group and donor	SDK2 LAMA4 SEZ6L2 SVEP1 HMCN1 NLGN2	9.59e-06	164	132	6	2ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS15 MCHR1 TYRO3 HMCN1 VCAN CSMD1	9.93e-06	165	132	6	6d315e0734079ad05336cc2c3f24d870c9105bc8
ToppCell	facs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS15 MCHR1 TYRO3 HMCN1 VCAN CSMD1	9.93e-06	165	132	6	84f5597b1bb75f42de9a224196bb8ac198bbe3bf
ToppCell	facs-Kidney\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUBN AASS HOGA1 HABP2 HSD3B2 SLC23A1	1.10e-05	168	132	6	d2f17a470e04f8f0edb111894027bcfc6ee1a12f
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 SLC44A4 ITGB4 ADAMTS9 AASS HABP2	1.39e-05	175	132	6	3f1b2e23fec953148fb0711e523c463adb07dca4
ToppCell	Frontal_cortex-Macroglia-ASTROCYTE\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	LCAT AASS HOGA1 PRSS50 UPP1	1.47e-05	104	132	5	bf27bc52f440d1e94108b35ad85ed593201164c9
ToppCell	Frontal_cortex-Macroglia-ASTROCYTE-Gja1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	LCAT AASS HOGA1 PRSS50 UPP1	1.47e-05	104	132	5	10e6c5b63c28d8c47e89ab130a7daf01700dd4e4
ToppCell	facs-Pancreas-Exocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 ITGB4 ADAMTS9 AASS JAG1 HABP2	1.58e-05	179	132	6	bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 SH3RF1 FAT3 DCC SVEP1 C1QTNF7	1.63e-05	180	132	6	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 SH3RF1 FAT3 DCC SVEP1 C1QTNF7	1.63e-05	180	132	6	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 CUBN PNPLA1 C1QTNF7 CSMD1 SUFU	1.68e-05	181	132	6	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KIF13B KIF23 ITGA3 HMCN1 UPP1 DNAH6	1.73e-05	182	132	6	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DHRS11 YOD1 ZFHX3 CACNA1H WDR90 C1QTNF7	1.90e-05	185	132	6	38486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCell	droplet-Heart-nan-18m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCHR1 SLC44A4 ITGB4 HABP2 CSMD1 DNAH6	1.90e-05	185	132	6	c61267cfadea018794f7964904445787629a40d1
ToppCell	droplet-Heart-nan-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCHR1 SLC44A4 ITGB4 HABP2 CSMD1 DNAH6	1.90e-05	185	132	6	3a592719d5643011954f89d5bb61a5e94682b68e
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PITPNM2 SALL3 LAMA4 ZC3H7B FHL3 IL6ST	1.90e-05	185	132	6	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 RNF213 B3GNT3 SLC44A4 SCCPDH CELSR2	1.90e-05	185	132	6	a6874dd3030d04380cc3c01de1069461aad4ef45
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DHRS11 YOD1 ZFHX3 CACNA1H WDR90 C1QTNF7	1.90e-05	185	132	6	3c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	MCHR1 SVEP1 TYRO3 HMCN1 ADAMTS9 C1QTNF7	2.02e-05	187	132	6	e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	CFH FAT3 LAMA4 SVEP1 HMCN1 C1QTNF7	2.02e-05	187	132	6	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 GRM5 SCCPDH SLCO1A2 JAG1 DNAH6	2.14e-05	189	132	6	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	CFH FAT3 LAMA4 SVEP1 HMCN1 VCAN	2.21e-05	190	132	6	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 FAT3 LAMA4 DCC SVEP1 VCAN	2.27e-05	191	132	6	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFH SDK2 FAT3 LAMA4 CBLB VCAN	2.27e-05	191	132	6	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	CFH SH3RF1 FAT3 LAMA4 ADAMTS9 JAG1	2.27e-05	191	132	6	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	15-Trachea-Epithelial-Submucosal_gland_basal\|Trachea / Age, Tissue, Lineage and Cell class	LAMA4 PRSS36 FZD7 EGR2 ADAMTS9 ADAMTS18	2.27e-05	191	132	6	409e12d2bb26b6d2ed025304ca6ace07df16638a
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH FAT3 LAMA4 SVEP1 HMCN1 C1QTNF7	2.27e-05	191	132	6	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LAMA4 SVEP1 VCAN LTBP3 C1QTNF7	2.34e-05	192	132	6	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LAMA4 SVEP1 VCAN LTBP3 C1QTNF7	2.34e-05	192	132	6	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFH FAT3 LAMA4 SVEP1 HMCN1 C1QTNF7	2.34e-05	192	132	6	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	Hippocampus-Endothelial\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CFH LAMA4 JAG1 SIX5 C1QTNF7 CNN2	2.34e-05	192	132	6	36deadab892d3e639a71f33697bb2d3cbbaa5372
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SVEP1 EGR2 VCAN LTBP3 C1QTNF7	2.41e-05	193	132	6	0a665531d581d4e3941e29d3f95569da8f166447
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	B3GNT3 GRM5 SCCPDH SLCO1A2 VCAN JAG1	2.41e-05	193	132	6	0f2167eef8203a5659c8c72e4e77646003d64797
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH LAMA4 SVEP1 VCAN LTBP3 C1QTNF7	2.41e-05	193	132	6	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SDK2 FAT3 LAMA4 SVEP1 HMCN1 AASS	2.41e-05	193	132	6	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH SVEP1 EGR2 VCAN LTBP3 C1QTNF7	2.41e-05	193	132	6	24ce1f37cca655415410d2403a52d1ebb3332280
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SDK2 FAT3 LAMA4 SVEP1 HMCN1 VCAN	2.48e-05	194	132	6	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 FAT3 LAMA4 DCC SVEP1 C1QTNF7	2.48e-05	194	132	6	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	CFH ITGB4 FZD7 NLGN2 LTBP3 CNN2	2.55e-05	195	132	6	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH FAT3 LAMA4 SVEP1 HMCN1 C1QTNF7	2.63e-05	196	132	6	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT3 LAMA4 SVEP1 HMCN1 AASS C1QTNF7	2.63e-05	196	132	6	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	CFH FAT3 LAMA4 SVEP1 HMCN1 C1QTNF7	2.70e-05	197	132	6	6c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH LAMA4 SVEP1 HMCN1 VCAN C1QTNF7	2.70e-05	197	132	6	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFH FAT3 LAMA4 SVEP1 HMCN1 VCAN	2.78e-05	198	132	6	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFH FAT3 LAMA4 SVEP1 HMCN1 VCAN	2.78e-05	198	132	6	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CFH LAMA4 SVEP1 HMCN1 AASS C1QTNF7	2.86e-05	199	132	6	28c1722deef3b8347371c7359be7c64b95780de3
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CFH LAMA4 SVEP1 ADAMTS9 VCAN JAG1	2.86e-05	199	132	6	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CFH LAMA4 SVEP1 ADAMTS9 VCAN JAG1	2.86e-05	199	132	6	251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SDK2 LAMA4 SVEP1 VCAN SMO IL6ST	2.86e-05	199	132	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH SDK2 LAMA4 SVEP1 HMCN1 C1QTNF7	2.86e-05	199	132	6	e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CFH LAMA4 SVEP1 ADAMTS9 VCAN JAG1	2.86e-05	199	132	6	117f4f43b6c06dda553799b1063e827bce697370
ToppCell	Tracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	B4GAT1 FAT3 CR1 USP19 CELSR2 EGR2	2.86e-05	199	132	6	4e4bdcd2e8b518156d5ebd294804180acaa3566b
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH FAT3 LAMA4 SVEP1 HMCN1 VCAN	2.94e-05	200	132	6	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH FAT3 LAMA4 SVEP1 HMCN1 C1QTNF7	2.94e-05	200	132	6	8c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH LAMA4 SVEP1 HMCN1 VCAN C1QTNF7	2.94e-05	200	132	6	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	Macroglial-Astrocytes-GFAP---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	FAT3 LCAT ITGB4 ADCY8 NCAN ADAMTS18	2.94e-05	200	132	6	88d66550781a3c9102ff7455f5cff6fb072943cd
ToppCell	Macroglial-Astrocytes-GFAP-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	FAT3 LCAT ITGB4 ADCY8 NCAN ADAMTS18	2.94e-05	200	132	6	d6a059b0ef763c281c60b1ac76da6079ea822f80
ToppCell	Macroglial-Astrocytes-GFAP--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	FAT3 LCAT ITGB4 ADCY8 NCAN ADAMTS18	2.94e-05	200	132	6	16269fa4adb28fc6ed032bbdba8781237dd0d249
ToppCell	Macroglial-Astrocytes-GFAP----L1-2\|Macroglial / cells hierarchy compared to all cells using T-Statistic	FAT3 LCAT ITGB4 ADCY8 NCAN ADAMTS18	2.94e-05	200	132	6	c6f43bbbd5df5f2c19ae385f1a6b6a330abede2f
ToppCell	Macroglial-Astrocytes-GFAP\|Macroglial / cells hierarchy compared to all cells using T-Statistic	FAT3 LCAT ITGB4 ADCY8 NCAN ADAMTS18	2.94e-05	200	132	6	79634b1086934412ae92f259ab43554ce545008f
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFH LAMA4 SVEP1 HMCN1 VCAN C1QTNF7	2.94e-05	200	132	6	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	Thalamus-Macroglia-ASTROCYTE\|Thalamus / BrainAtlas - Mouse McCarroll V32	SALL3 LCAT AASS PRSS50 UPP1	3.05e-05	121	132	5	c3a4dfd19b7e8654e859df605d55155b530ad009
ToppCell	Thalamus-Macroglia-ASTROCYTE-Gja1\|Thalamus / BrainAtlas - Mouse McCarroll V32	SALL3 LCAT AASS PRSS50 UPP1	3.05e-05	121	132	5	c3efd44bd01c12ef8c7ce4cc351af1540b70a63c
ToppCell	facs-Marrow-B-cells-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS15 SLC29A3 GPR25 HABP2 CSMD1	6.76e-05	143	132	5	6df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TMPRSS15 TOPAZ1 DCC GRM5 ADCY8	8.48e-05	150	132	5	0205318a870e091add66ee4305747dda9f51510d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CFH TOPAZ1 CR1 TYRO3 ADAMTS9	9.89e-05	155	132	5	90e629681a72baacc7981b82883866a487638dbc
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	SDK2 LAMA4 SVEP1 HMCN1 NLGN2	1.12e-04	159	132	5	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	KIF23 CEBPE CR1 TYRO3 SMO	1.22e-04	162	132	5	a957c7e347189b72fbd47db3075bb5e879a21c67
ToppCell	Posterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Htra1)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	AASS ANKAR PRSS50 UPP1	1.25e-04	86	132	4	c6c0e8e562ffc705e0cd3f503a9e43ca2669e9b0
ToppCell	Posterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Htra1)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	AASS ANKAR PRSS50 UPP1	1.25e-04	86	132	4	c1181a7e9f4cbde5a3bee7b54d6448dfce58b238
ToppCell	Posterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Igfbp2_(Htra1)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	AASS ANKAR PRSS50 UPP1	1.25e-04	86	132	4	4263673abf183f2e04f1a2bf37e365a25b8cb0b4
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPE CPNE3 ZFHX3 UPP1 CNN2	1.33e-04	165	132	5	9acf03b5a20170721380045b5c268825e8f315dd
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_2\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	MCHR1 DHRS11 CACNA1H SUFU	1.36e-04	88	132	4	3a92f76e4db86486cb265301e6056af791a11a63
ToppCell	droplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PITPNM2 B3GNT3 BRPF1 JAG1 EFR3B	1.40e-04	167	132	5	a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCell	Adult-Mesenchymal-myofibroblast_cell\|Adult / Lineage, Cell type, age group and donor	CFH SDK2 HMCN1 SMO C1QTNF7	1.40e-04	167	132	5	d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	CFH FCRL2 CR1 SVEP1 HMCN1	1.40e-04	167	132	5	d2230c894ccf9dbba9196e079ae81f384d43da63
Disease	Colorectal Carcinoma	CAD SALL3 CUBN DCC SLC44A4 ADCY8 SLCO1A2 ADAMTS18 FLCN UQCRC2 FHL3 UHRF2 EP300 IL6ST	2.57e-06	702	129	14	C0009402
Disease	Ly6/PLAUR domain-containing protein 3 measurement	CFH PHLDB3	1.90e-05	2	129	2	EFO_0021931
Disease	interferon gamma receptor 1 measurement	CFH HABP2	1.90e-05	2	129	2	EFO_0020484
Disease	Adenoid Cystic Carcinoma	SMC1A ITGB4 VCAN JAG1 EP300	7.98e-05	100	129	5	C0010606
Disease	brain measurement, neuroimaging measurement	VWA5B2 FAT3 DCC PNKD ADAMTS9 VCAN JAG1 ADAMTS18 ZFHX3 SUFU	1.58e-04	550	129	10	EFO_0004346, EFO_0004464
Disease	lysophosphatidylcholine acyltransferase 2 measurement	CFH HABP2	1.88e-04	5	129	2	EFO_0801775
Disease	Colorectal cancer	DCC FLCN EP300	2.21e-04	27	129	3	cv:C0346629
Disease	Neoplasm of the large intestine	DCC FLCN EP300	2.21e-04	27	129	3	cv:C0009404
Disease	COLORECTAL CANCER	DCC FLCN EP300	2.21e-04	27	129	3	114500
Disease	Junctional Epidermolysis Bullosa	ITGA3 ITGB4	2.81e-04	6	129	2	C0079301
Disease	Chanarin-Dorfman syndrome (implicated_via_orthology)	PNPLA2 PNPLA1	2.81e-04	6	129	2	DOID:0050729 (implicated_via_orthology)
Disease	total cholesterol measurement, C-reactive protein measurement	SLC44A4 CELSR2 NCAN	3.35e-04	31	129	3	EFO_0004458, EFO_0004574
Disease	alcohol consumption measurement	CAD TOPAZ1 BBS1 DCC GRM5 SEZ6L2 CRB1 FZD7 TYRO3 ZFHX3 WDR90 CSMD1 ZC3H7B SUFU EP300	3.55e-04	1242	129	15	EFO_0007878
Disease	obesity (implicated_via_orthology)	PNPLA2 SDK2 BBS1 PNPLA1 ADAMTS9 ZFHX3	3.77e-04	215	129	6	DOID:9970 (implicated_via_orthology)
Disease	Bladder Neoplasm	SMC1A NCOR1 NCAN EP300 SMC1B	3.84e-04	140	129	5	C0005695
Disease	junctional epidermolysis bullosa (is_implicated_in)	ITGA3 ITGB4	3.93e-04	7	129	2	DOID:3209 (is_implicated_in)
Disease	retinal detachment	FAT3 GRM5	3.93e-04	7	129	2	EFO_0005773
Disease	Malignant neoplasm of urinary bladder	SMC1A NCOR1 NCAN EP300 SMC1B	3.97e-04	141	129	5	C0005684
Disease	HOMA-IR	SLC29A3 DCC CSMD1	4.05e-04	33	129	3	EFO_0004501
Disease	primary dental caries	CFH CUBN ADAMTS18	4.42e-04	34	129	3	EFO_0600095
Disease	tyrosine-protein kinase receptor TYRO3 measurement	CFH TYRO3	5.22e-04	8	129	2	EFO_0020829
Disease	low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	LCAT IGF2R CELSR2 SLCO1A2 NCAN	5.76e-04	153	129	5	EFO_0004611, EFO_0020944
Disease	complement factor H-related protein 5 measurement	CFH CRB1 ADAM5	8.27e-04	42	129	3	EFO_0008098
Disease	Bone Diseases	JAG1 LTBP3	8.34e-04	10	129	2	C0005940
Disease	membranoproliferative glomerulonephritis (implicated_via_orthology)	CFH EP300	8.34e-04	10	129	2	DOID:2920 (implicated_via_orthology)
Disease	Malignant neoplasm of salivary gland	ITGB4 VCAN JAG1	1.01e-03	45	129	3	C0220636
Disease	gastrin-releasing peptide measurement	CFH HABP2	1.02e-03	11	129	2	EFO_0022000
Disease	hemopexin measurement	CFH CRB1	1.02e-03	11	129	2	EFO_0008149
Disease	neurotic disorder	DCC GRM5 CSMD1 ZC3H7B	1.03e-03	101	129	4	EFO_0004257
Disease	Acute Promyelocytic Leukemia	CEBPE SMC1A SMO	1.08e-03	46	129	3	C0023487
Disease	Gastrointestinal Stromal Sarcoma	SALL3 SMO SUFU	1.15e-03	47	129	3	C3179349
Disease	Salivary Gland Neoplasms	ITGB4 VCAN JAG1	1.15e-03	47	129	3	C0036095
Disease	Cooley's anemia	CAD CACNA1H	1.22e-03	12	129	2	C0002875
Disease	Thalassemia Minor	CAD CACNA1H	1.22e-03	12	129	2	C0085578
Disease	beta Thalassemia	CAD CACNA1H	1.22e-03	12	129	2	C0005283
Disease	Amelogenesis Imperfecta	ITGB4 LTBP3	1.22e-03	12	129	2	C0002452
Disease	Thalassemia Intermedia	CAD CACNA1H	1.22e-03	12	129	2	C0271979
Disease	Gastrointestinal Stromal Tumors	SALL3 SMO SUFU	1.38e-03	50	129	3	C0238198
Disease	creatinine measurement	CFH CUBN SLC44A4 CBLB IGF2R CELSR2 CPNE3 ZFHX3 CFAP70 UHRF2 SUFU SLC23A1	1.43e-03	995	129	12	EFO_0004518
Disease	Leber congenital amaurosis (implicated_via_orthology)	DHRS13 CRB1	1.43e-03	13	129	2	DOID:14791 (implicated_via_orthology)
Disease	respiratory quotient	CAMK1D DCC	1.67e-03	14	129	2	EFO_0005189
Disease	wet macular degeneration	CFH SLC44A4	1.67e-03	14	129	2	EFO_0004683
Disease	Hemoglobin F Disease	CAD CACNA1H	1.92e-03	15	129	2	C0019025
Disease	cancer biomarker measurement	B3GNT3 PPIP5K1	1.92e-03	15	129	2	EFO_0005127
Disease	chenodeoxycholate measurement	DCC HMCN1	1.92e-03	15	129	2	EFO_0010471
Disease	hepatoblastoma (is_marker_for)	ZFHX3 SMO	1.92e-03	15	129	2	DOID:687 (is_marker_for)
Disease	glycerate measurement	HMCN1 SLC23A1	1.92e-03	15	129	2	EFO_0021029
Disease	Renal Cell Carcinoma	PNKD LMAN2L FLCN CNN2	2.45e-03	128	129	4	C0007134
Disease	Sarcomatoid Renal Cell Carcinoma	PNKD LMAN2L FLCN CNN2	2.45e-03	128	129	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	PNKD LMAN2L FLCN CNN2	2.45e-03	128	129	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	PNKD LMAN2L FLCN CNN2	2.45e-03	128	129	4	C1266044
Disease	Papillary Renal Cell Carcinoma	PNKD LMAN2L FLCN CNN2	2.45e-03	128	129	4	C1306837
Disease	pre-malignant neoplasm (biomarker_via_orthology)	SMO SUFU	2.47e-03	17	129	2	DOID:0060071 (biomarker_via_orthology)
Disease	Moyamoya Disease	RNF213 JAG1	2.47e-03	17	129	2	C0026654
Disease	glucose homeostasis measurement, acute insulin response measurement	SDK2 MICU3	2.77e-03	18	129	2	EFO_0006831, EFO_0006896
Disease	Age-related macular degeneration	CFH HMCN1	2.77e-03	18	129	2	cv:C0242383
Disease	vital capacity	CFH DCC ADCY8 SVEP1 NCOR1 HMCN1 TULP4 EFR3B ADAMTS18 ZFHX3 LTBP3 FHL3 NNT	3.02e-03	1236	129	13	EFO_0004312
Disease	periodontitis	FAT3 IGF2R ZFHX3 CSMD1 UHRF2	3.04e-03	223	129	5	EFO_0000649
Disease	anxiety	MCHR1 KAT8 LTBP3 CSMD1 ZC3H7B	3.04e-03	223	129	5	EFO_0005230
Disease	breast carcinoma (is_marker_for)	IGF2R ZFHX3 EP300	3.06e-03	66	129	3	DOID:3459 (is_marker_for)
Disease	Congenital hernia of foramen of Morgagni	MYOD1 IGF2R	3.09e-03	19	129	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	MYOD1 IGF2R	3.09e-03	19	129	2	C0265700
Disease	Meningioma	SMO SUFU	3.09e-03	19	129	2	C0025286
Disease	smoking cessation	DCC USP19 ZFHX3 CACNA1H NLGN2 ZC3H7B	3.13e-03	325	129	6	EFO_0004319
Disease	cortical surface area measurement, neuroimaging measurement	FAT3 ADAMTS9 VCAN ADAMTS18 ZFHX3	3.28e-03	227	129	5	EFO_0004346, EFO_0010736
Disease	schizophrenia (implicated_via_orthology)	GRM5 NLGN2 CSMD1	3.33e-03	68	129	3	DOID:5419 (implicated_via_orthology)
Disease	Osteoarthritis of hip	SMO LTBP3	3.42e-03	20	129	2	C0029410
Disease	bipolar I disorder	CUBN PRSS36 LMAN2L NCAN	3.47e-03	141	129	4	EFO_0009963
Disease	Congenital diaphragmatic hernia	MYOD1 IGF2R	3.77e-03	21	129	2	C0235833
Disease	bipolar disorder	CAMK1D MCHR1 PRSS36 SVEP1 LMAN2L KCNU1 NCAN SUFU	3.94e-03	577	129	8	MONDO_0004985
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	PNKD LMAN2L FLCN CNN2	4.12e-03	148	129	4	C0279702

Protein segments in the cluster

Peptide	Gene	Start	Entry
LYPGLEGFRPVEQCN	ALKBH4	141	Q9NXW9
LGDCYYCVSGLPEPR	ADCY8	461	P40145
YGSDCPPPNQRRVYI	EP300	1381	Q09472
TCALRPTYIYGEGGP	HSD3B2	181	P26439
GDLPYCLPDTYVRDG	ADAM5	186	Q6NVV9
GVLCYELLVGYPPFE	AURKC	226	Q9UQB9
KCEDPGIPNYGYRIR	CSMD1	1216	Q96PZ7
VRYPIRAPRVGCYGD	VCAN	206	P13611
YYECEPRGGQQPLEF	CEBPE	6	Q15744
VGEVRPFYYGLCTPC	B4GAT1	281	O43505
ELELCPAGDLPYGYV	GPR25	26	O00155
IESYISYCGGLPAPE	AASS	626	Q9UDR5
AYRSCLPQIKLYGPT	CPNE3	381	O75131
TYPEGTQAIYKCRPG	CFH	41	P08603
ECPPNYLGPYCETRI	CELSR2	1856	Q9HCU4
YLGPYCETRIDQPCP	CELSR2	1861	Q9HCU4
PQYGGLFCPGSSRIY	ADAMTS18	621	Q8TE60
IPKSPGLYAIGYEEC	MSANTD2	416	Q6P1R3
LANPLYCPDYRIGKV	UQCRC2	186	P22695
QYPGASCYPEGIINI	EGR2	101	P11161
YYVVEGGVLNPACAP	YOD1	166	Q5VVQ6
SCQLPPAYYDTRIGQ	ANKAR	131	Q7Z5J8
PAVGDSGRYPLYQLL	PHLDB3	426	Q6NSJ2
SGRYPLYQLLNCGRG	PHLDB3	431	Q6NSJ2
NCYLDGEGPFRLSPY	PCDH20	466	Q8N6Y1
YCGLIPPSLQGVRYV	PNPLA2	151	Q96AD5
PAYANGPVQGYRLFC	DCC	551	P43146
PLPYDRFCYGLAVVE	KLHL34	556	Q8N239
QIYCYLQRIGIGLSP	GRM5	641	P41594
GYYGGPCRAPLQELS	HOGA1	296	Q86XE5
PCIYLVDSGGAYLPR	MCCC2	166	Q9HCC0
PVGCVRIIPYSSQYE	FLCN	396	Q8NFG4
CILTLPPYQRRGYGK	KAT8	316	Q9H7Z6
SLTYGICNGSLYPEP	TMPRSS15	496	P98073
YPDGRSYNPDLTGLC	CBLB	331	Q13191
AIRTAPNPYYCQVGL	LTK	476	P29376
PDGYTNRTGAVYLCP	ITGA3	81	P26006
LCYKYRGPESGLPEA	KPTN	336	Q9Y664
YILLSGYPPFVGRCG	MKNK2	286	Q9HBH9
PPSGARRRNCYEGAY	MYOD1	216	P15172
GSGYNSDRLCLPYIP	EFR3B	666	Q9Y2G0
CLYLNVYAPARAPGD	CES4A	116	Q5XG92
VYCGLIPPTYRGVRY	PNPLA1	156	Q8N8W4
CLPGKVIQIPGYYGL	LMLN2	576	A0A1B0GTW7
VIQIPGYYGLLFCPR	LMLN2	581	A0A1B0GTW7
DCIEVPGVRLPRGYY	LMAN2L	236	Q9H0V9
PQIYILPGCALYSGD	KCNU1	771	A8MYU2
GLVGLVCYQLYGDPR	MICU3	76	Q86XE3
VCYQLYGDPRAGSPA	MICU3	81	Q86XE3
PRYQRYPLGDGCSTL	PITPNM2	786	Q9BZ72
PRCERPLQGYSVEYQ	ITGB4	1551	P16144
GYYLQPGQIPCSVDS	HMCN1	441	Q96RW7
IGSNVTLPCYVQGYP	HMCN1	806	Q96RW7
YQGILPPGTLCVLYA	PRSS36	741	Q5K4E3
PGDCVQNYLTLYDGP	CUBN	3561	O60494
VPPYLGYRFLGERDC	FZD7	216	O75084
GCITAELYTGYPLFP	DYRK4	291	Q9NR20
GRGQCLITQSPPYYR	HABP2	121	Q14520
YGECLLNEPESRPYP	ADAMTS9	491	Q9P2N4
YEYLGACPRLVITPL	DNAH6	1436	Q9C0G6
GRKYIQTDSGPYCVP	FHL3	16	Q13643
CYLITVTPVYADGPG	IL6ST	491	P40189
IIAPPGYEAYECRGV	BMP10	341	O95393
YECRPGYSGRPFSII	CR1	71	P17927
INISIGYRYPPICLG	ERVK-24	41	P61566
INISIGYRYPPICLG	ERVK-7	41	P61567
LCPQGGPSCEYYLVL	CFAP70	921	Q5T0N1
PGYVGQYCGLRPVVV	FAT3	4126	Q8TDW7
ARACPYYGSRLAIPA	DDX12P	366	Q92771
PYNQPGICYTLVRLP	COPG2	696	Q9UBF2
EVVTQNERYPPYCGG	B3GNT3	256	Q9Y2A9
NCYPGYRLKASRPPV	LTBP3	686	Q9NS15
NRGGLCYYPLFNTPV	MARVELD2	316	Q8N4S9
VGCGIRLPNPDTDLY	MCHR1	261	Q99705
PGVEVYCLYGVGLPT	LCAT	331	P04180
PRQVLYPRNSTGAYC	SLC44A4	61	Q53GD3
CYVPARSLPYNQPGT	COPG1	691	Q9Y678
YLAPGYCAQTGAALP	FIGNL2	166	A6NMB9
YPSRQIAICLDPYCG	DIP2A	1186	Q14689
CEALRGSPPILYQFY	FCRL2	321	Q96LA5
PYEGPNCLREYVAGR	CRB1	701	P82279
LASGPCVYVYKNLRP	BBS1	106	Q8NFJ9
ACGPLGYIRNPYNIF	CACNA1H	846	O95180
KSAGYPGTLIPYRCD	DHRS11	56	Q6UWP2
GYRLVYEPCSPVDGV	SDK2	1756	Q58EX2
VDGRLTYPTCGIGYP	SASS6	516	Q6UVJ0
EYLDNVPTCSGIPYG	SALL3	486	Q9BXA9
CLYLNLYVPTEDGPL	NLGN2	141	Q8NFZ4
ENYSPRYICSIPGLP	C1QTNF7	26	Q9BXJ2
VLVYYNLVKAPPCGG	DHRS13	16	Q6UX07
QGNPLALVPYYRGLT	LRRC43	256	Q8N309
CERCAPGYYGNPLLI	LAMA4	166	Q16363
PGYYGNPLLIGSTCK	LAMA4	171	Q16363
DLVNGYRCICPPGYA	JAG1	466	P78504
VGVYCRVRPLGFPDQ	KIF23	26	Q02241
PGYGLCAAKAQYPIA	NNT	931	Q13423
YFRCNPGYGLLVRPS	KIF13B	1751	Q9NQT8
YLSVCNPLPYIPGCQ	IGF2R	1121	P11717
ERVYGGCLCYGPPIE	TARS1	166	P26639
PGLQRPEDRFCGTYI	SLC29A3	41	Q9BZD2
PGRDYPNICAGTDRY	UPP1	81	Q16831
CRVYGSPQDGIPYLT	PNKD	191	Q8N490
LNCVGPYRFYGEPVI	SCCPDH	96	Q8NBX0
CNIPIGTPVSGYALY	NCOR1	946	O75376
VRYPITQSRPGCYGD	NCAN	216	O14594
LKACYRGNRYPTPDE	SIX5	216	Q8N196
YTGCIIREYPNSGPQ	SHPRH	351	Q149N8
YNLPPICIGYIIGGL	SLCO1A2	361	P46721
CLNPGVPENGYQTLY	SEZ6L2	771	Q6UXD5
CGLRLLSQTQGPPDY	MRPL49	21	Q13405
VSYTCNPGYELLGNP	SVEP1	2681	Q4LDE5
SIGVIAYILLCGYPP	CAMK1D	206	Q8IU85
RGIPQLPCAKALYNY	SH3RF1	131	Q7Z6J0
AKCRGYPSYPALIID	BRPF1	1091	P55201
VFGLGRQIYDPKYCP	CNN2	261	Q99439
LCLRLQYPAGYPSDK	UHRF2	631	Q96PU4
CLSGIYYRLPGLEQV	RNF213	791	Q63HN8
PCYTLYLEYLGGLVP	TULP4	456	Q9NRJ4
GLCRPENIGYPFLVS	USP19	831	O94966
GELTSLCYGAPPLLY	WDR90	1301	Q96KV7
IGDYYACARLAGAPP	SLC23A1	336	Q9UHI7
LYCNGVLEPLYLCPN	SLC25A39	76	Q9BZJ4
VPLHSGYRCPLQGLY	PYROXD2	536	Q8N2H3
EPYLEGISYNCVAPG	SMC1B	1101	Q8NDV3
ELGNRYQLPVYCLAP	UBTD2	111	Q8WUN7
AIYGECRRLYPDQPN	SUFU	36	Q9UMX1
YPGSVYGRLIDLCQP	SMC1A	511	Q14683
LYYHGKEQVPRGCPD	ACP6	376	Q9NPH0
REFNIPPYLQCIRYG	VCPIP1	806	Q96JH7
EPLRYNVCLGSVLPY	SMO	71	Q99835
VGYPCVVRPSYVLSG	CAD	1081	P27708
LSLGCYPPLEGNLYR	TOPAZ1	1561	Q8N9V7
LYLQLDPAIPGVYFG	ATP6V0A4	501	Q9HBG4
IPALYPGDQLLGYCS	VWA5B2	546	Q8N398
LKYSNYVRPICLPGT	PRSS50	216	Q9UI38
DCRYILTPGGLAEQP	TYRO3	846	Q06418
PLCYLRYSRGVLSPG	PPIP5K1	816	Q6PFW1
ANPVNYGRPYRLSCV	TSR3	151	Q9UJK0
PRLARGESYTCGYKP	ZFHX3	711	Q15911
QLCYPKTGPRAGDYT	ZC3H7B	426	Q9UGR2
AYEGGLPPRVNYSLL	NAGA	191	P17050