Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGTPase activator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TAGAP TBC1D3I TBC1D3G TBC1D3C TBC1D3B ANKRD27 TBC1D3K TBC1D3F

3.42e-112797513GO:0005096
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RASGRF1 TAGAP RIMS1 TBC1D3I TBC1D3G TBC1D3C TBC1D3B ANKRD27 TBC1D3K TBC1D3F SOS2

5.08e-115077516GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RASGRF1 TAGAP RIMS1 TBC1D3I TBC1D3G TBC1D3C TBC1D3B ANKRD27 TBC1D3K TBC1D3F SOS2

5.08e-115077516GO:0030695
GeneOntologyMolecularFunctionenzyme activator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TAGAP XRCC5 TBC1D3I TBC1D3G TBC1D3C TBC1D3B ANKRD27 TBC1D3K TBC1D3F

1.31e-076567514GO:0008047
GeneOntologyMolecularFunctioncalmodulin binding

UNC13B CACNA1C CACNA1S CAMKV UNC13C UNC13A RYR2 RYR3

2.38e-06230758GO:0005516
GeneOntologyMolecularFunctionenzyme regulator activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RASGRF1 TAGAP NAP1L2 RIMS1 XRCC5 TBC1D3I TBC1D3G TBC1D3C TBC1D3B ANKRD27 TBC1D3K TBC1D3F SOS2

3.69e-0614187518GO:0030234
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

9.04e-06129756GO:0005262
GeneOntologyMolecularFunctionphorbol ester receptor activity

UNC13B UNC13C

1.39e-052752GO:0001565
GeneOntologyMolecularFunctionnon-kinase phorbol ester receptor activity

UNC13B UNC13C

1.39e-052752GO:0001566
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1C CACNA1D CACNA1S

1.80e-0514753GO:0008331
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

2.22e-05151756GO:0015085
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1C CACNA1D CACNA1S TRPA1

2.66e-0546754GO:0005245
GeneOntologyMolecularFunctiondiacylglycerol binding

UNC13B UNC13C UNC13A

2.75e-0516753GO:0019992
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

TRPA1 RYR2 RYR3

3.99e-0518753GO:0015278
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1C CACNA1D CACNA1S TRPA1 SCN8A KCNAB1 RYR2 RYR3

4.33e-05343758GO:0005261
GeneOntologyMolecularFunctionmolecular function activator activity

CACNA1S TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TAGAP XRCC5 TBC1D3I TBC1D3G TBC1D3C TBC1D3B ANKRD27 TBC1D3K TBC1D3F

4.54e-0512337515GO:0140677
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

8.31e-054752GO:0005219
GeneOntologyMolecularFunctionsyntaxin-1 binding

UNC13B UNC13C UNC13A

9.73e-0524753GO:0017075
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in cardiac muscle cell action potential

CACNA1C CACNA1D

1.38e-045752GO:0086007
GeneOntologyMolecularFunctionSNARE binding

UNC13B UNC13C TXLNG ANKRD27 UNC13A

1.60e-04136755GO:0000149
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

2.07e-046752GO:0048763
GeneOntologyMolecularFunctionligand-gated calcium channel activity

TRPA1 RYR2 RYR3

2.12e-0431753GO:0099604
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

TRPA1 RYR2 RYR3

2.56e-0433753GO:0005217
GeneOntologyMolecularFunctiongated channel activity

CACNA1C CACNA1D CACNA1S TRPA1 KCNAB1 RYR2 RYR3

2.58e-04334757GO:0022836
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1C CACNA1D CACNA1S TRPA1 KCNAB1

2.69e-04152755GO:0022843
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1C CACNA1D CACNA1S TRPA1 SCN8A KCNAB1 RYR2 RYR3

3.21e-04459758GO:0005216
GeneOntologyMolecularFunctionsyntaxin binding

UNC13B UNC13C TXLNG UNC13A

3.23e-0487754GO:0019905
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1C CACNA1D CACNA1S TRPA1 SCN8A KCNAB1 RYR2 RYR3

3.51e-04465758GO:0046873
GeneOntologyMolecularFunction5'-deoxyribose-5-phosphate lyase activity

POLG XRCC5

3.84e-048752GO:0051575
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CYC1 CACNA1C CACNA1D CACNA1S TRPA1 SCN8A KCNAB1 RYR2 RYR3

5.55e-04627759GO:0022890
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1C CACNA1D CACNA1S TRPA1 KCNAB1

6.13e-04182755GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1C CACNA1D CACNA1S TRPA1 KCNAB1

6.45e-04184755GO:0022832
GeneOntologyMolecularFunctionchannel activity

CACNA1C CACNA1D CACNA1S TRPA1 SCN8A KCNAB1 RYR2 RYR3

7.79e-04525758GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1C CACNA1D CACNA1S TRPA1 SCN8A KCNAB1 RYR2 RYR3

7.89e-04526758GO:0022803
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CYC1 CACNA1C CACNA1D CACNA1S TRPA1 SCN8A KCNAB1 RYR2 RYR3

8.35e-04664759GO:0008324
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CYC1 CACNA1C CACNA1D CACNA1S TRPA1 SCN8A KCNAB1 RYR2 RYR3

2.09e-03758759GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CYC1 CACNA1C CACNA1D CACNA1S TRPA1 SCN8A KCNAB1 RYR2 RYR3

2.83e-03793759GO:0015075
GeneOntologyMolecularFunctiondamaged DNA binding

SMC6 XPA XRCC5

3.90e-0384753GO:0003684
GeneOntologyMolecularFunctionprotein domain specific binding

CACNA1C CACNA1D FHOD1 TFDP3 KCNAB1 AATF XPA RIMS1 UNC13A

5.39e-03875759GO:0019904
GeneOntologyMolecularFunctionalpha-actinin binding

CACNA1C CACNA1D

6.03e-0331752GO:0051393
GeneOntologyMolecularFunctionATP-dependent activity

MMAA EP400 SMC6 HFM1 KIF4B XRCC5 ABCA9

8.20e-03614757GO:0140657
GeneOntologyMolecularFunctiontransporter activity

CYC1 CACNA1C CACNA1D CACNA1S TRPA1 STARD4 SCN8A KCNAB1 ABCA9 RYR2 RYR3

8.44e-0312897511GO:0005215
GeneOntologyBiologicalProcessactivation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RASGRF1 TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

5.04e-151097512GO:0090630
GeneOntologyBiologicalProcesspositive regulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RASGRF1 TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

7.75e-112447512GO:0043547
GeneOntologyBiologicalProcessregulation of GTPase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RASGRF1 PAFAH1B1 TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.22e-103357513GO:0043087
GeneOntologyBiologicalProcesspresynaptic dense core vesicle exocytosis

UNC13B UNC13C RIMS1 UNC13A

3.33e-0810754GO:0099525
GeneOntologyBiologicalProcessneuronal dense core vesicle exocytosis

UNC13B UNC13C RIMS1 UNC13A

7.81e-0812754GO:0099011
GeneOntologyBiologicalProcessdense core granule priming

UNC13B UNC13C UNC13A

1.84e-074753GO:0061789
GeneOntologyBiologicalProcessdense core granule exocytosis

UNC13B UNC13C RIMS1 UNC13A

2.13e-0715754GO:1990504
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RASGRF1 TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.31e-074997512GO:0051345
GeneOntologyBiologicalProcesssynaptic vesicle docking

UNC13B UNC13C RIMS1 UNC13A

3.70e-0717754GO:0016081
GeneOntologyBiologicalProcessorganelle localization by membrane tethering

UNC13B ESYT3 PDZD8 UNC13C RIMS1 UNC13A

6.57e-0785756GO:0140056
GeneOntologyBiologicalProcessmembrane docking

UNC13B ESYT3 PDZD8 UNC13C RIMS1 UNC13A

9.84e-0791756GO:0022406
GeneOntologyBiologicalProcesscalcium ion-regulated exocytosis of neurotransmitter

UNC13B UNC13C RIMS1 UNC13A

1.92e-0625754GO:0048791
GeneOntologyBiologicalProcesspositive regulation of molecular function

CACNA1C CACNA1D TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RASGRF1 HIPK1 XRCC5 TBC1D3I IL1RAP TBC1D3G TBC1D3C TBC1D3B RYR2 TBC1D3K TBC1D3F

2.63e-0614307518GO:0044093
GeneOntologyBiologicalProcessdense core granule localization

UNC13B UNC13C RIMS1 UNC13A

3.09e-0628754GO:0032253
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

CACNA1C CACNA1D TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RASGRF1 XRCC5 TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

3.60e-0610287515GO:0043085
GeneOntologyBiologicalProcesssynaptic vesicle priming

UNC13B UNC13C RIMS1 UNC13A

4.71e-0631754GO:0016082
GeneOntologyBiologicalProcesssecretory granule localization

UNC13B UNC13C RIMS1 UNC13A

6.88e-0634754GO:0032252
GeneOntologyBiologicalProcesscellular response to caffeine

CACNA1S RYR2 RYR3

7.46e-0611753GO:0071313
GeneOntologyBiologicalProcesscalcium-ion regulated exocytosis

UNC13B CACNA1C UNC13C RIMS1 UNC13A

1.22e-0582755GO:0017156
GeneOntologyBiologicalProcesspositive regulation of synaptic vesicle priming

UNC13B RIMS1

1.30e-052752GO:0010808
GeneOntologyBiologicalProcessdense core granule docking

UNC13B UNC13A

1.30e-052752GO:0061790
GeneOntologyBiologicalProcessregulation of hydrolase activity

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D RASGRF1 PAFAH1B1 TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.51e-058787513GO:0051336
GeneOntologyBiologicalProcessregulation of synaptic vesicle priming

UNC13B RIMS1 UNC13A

1.63e-0514753GO:0010807
GeneOntologyBiologicalProcesscellular response to purine-containing compound

CACNA1S RYR2 RYR3

1.63e-0514753GO:0071415
GeneOntologyBiologicalProcessvesicle docking involved in exocytosis

UNC13B UNC13C RIMS1 UNC13A

1.96e-0544754GO:0006904
GeneOntologyBiologicalProcessresponse to caffeine

CACNA1S RYR2 RYR3

5.86e-0521753GO:0031000
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

CACNA1C CACNA1D SCN8A RYR2

7.67e-0562754GO:0086002
GeneOntologyBiologicalProcessvesicle docking

UNC13B UNC13C RIMS1 UNC13A

9.23e-0565754GO:0048278
GeneOntologyBiologicalProcesspositive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

CACNA1C CACNA1D

1.30e-045752GO:1904879
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

1.39e-04217756GO:0097553
GeneOntologyBiologicalProcessstriated muscle contraction

CACNA1C CACNA1D CACNA1S SCN8A RYR2 RYR3

1.39e-04217756GO:0006941
GeneOntologyBiologicalProcessnegative regulation of synaptic plasticity

UNC13B UNC13C

1.94e-046752GO:0031914
GeneOntologyBiologicalProcessregulation of neuronal synaptic plasticity

UNC13B RASGRF1 RIMS1 UNC13A

2.38e-0483754GO:0048168
GeneOntologyBiologicalProcesscell-cell signaling involved in cardiac conduction

CACNA1C CACNA1D RYR2

2.55e-0434753GO:0086019
GeneOntologyBiologicalProcesscardiac muscle cell action potential

CACNA1C CACNA1D SCN8A RYR2

2.86e-0487754GO:0086001
GeneOntologyBiologicalProcessmembrane depolarization during action potential

CACNA1C CACNA1D SCN8A

3.02e-0436753GO:0086010
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum

CACNA1C RYR2 RYR3

3.28e-0437753GO:0014808
GeneOntologyBiologicalProcesscardiac muscle cell contraction

CACNA1C CACNA1D SCN8A RYR2

3.69e-0493754GO:0086003
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by endoplasmic reticulum

CACNA1C RYR2 RYR3

3.84e-0439753GO:1903514
GeneOntologyBiologicalProcesscellular response to alkaloid

CACNA1S RYR2 RYR3

4.14e-0440753GO:0071312
GeneOntologyBiologicalProcesssarcoplasmic reticulum calcium ion transport

CACNA1C RYR2 RYR3

5.49e-0444753GO:0070296
GeneOntologyBiologicalProcessestablishment of centrosome localization

FHOD1 PAFAH1B1

5.76e-0410752GO:0051660
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell signaling

CACNA1D RYR2

5.76e-0410752GO:0086018
GeneOntologyBiologicalProcessSA node cell action potential

CACNA1D RYR2

5.76e-0410752GO:0086015
GeneOntologyBiologicalProcesspositive regulation of inhibitory postsynaptic potential

UNC13B RIMS1

5.76e-0410752GO:0097151
GeneOntologyBiologicalProcessacrosomal vesicle exocytosis

UNC13B RIMS1

5.76e-0410752GO:0060478
GeneOntologyBiologicalProcessmuscle contraction

CACNA1C CACNA1D CACNA1S TRPA1 SCN8A RYR2 RYR3

6.25e-04400757GO:0006936
GeneOntologyBiologicalProcessexocytic process

UNC13B UNC13C RIMS1 UNC13A

6.27e-04107754GO:0140029
GeneOntologyBiologicalProcessribosomal small subunit biogenesis

RPS9 AATF XRCC5 RIOK2

6.49e-04108754GO:0042274
GeneOntologyBiologicalProcessacrosome reaction

UNC13B GARIN1B RIMS1

6.67e-0447753GO:0007340
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell communication

CACNA1D RYR2

7.02e-0411752GO:0086070
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1C CACNA1D CACNA1S

7.10e-0448753GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1C CACNA1D CACNA1S

7.10e-0448753GO:1902656
GeneOntologyBiologicalProcessaction potential

CACNA1C CACNA1D TRPA1 SCN8A RYR2

8.30e-04201755GO:0001508
GeneOntologyBiologicalProcessmodulation of inhibitory postsynaptic potential

UNC13B RIMS1

8.41e-0412752GO:0098828
GeneOntologyBiologicalProcessspontaneous neurotransmitter secretion

UNC13B RIMS1

8.41e-0412752GO:0061669
GeneOntologyBiologicalProcessregulation of ventricular cardiac muscle cell action potential

CACNA1C RYR2

8.41e-0412752GO:0098911
GeneOntologyBiologicalProcessAV node cell to bundle of His cell signaling

CACNA1C RYR2

8.41e-0412752GO:0086027
GeneOntologyBiologicalProcessAV node cell action potential

CACNA1C RYR2

8.41e-0412752GO:0086016
GeneOntologyBiologicalProcessurinary bladder smooth muscle contraction

CACNA1C TRPA1

8.41e-0412752GO:0014832
GeneOntologyBiologicalProcessorganelle localization

UNC13B ESYT3 FHOD1 PAFAH1B1 PDZD8 UNC13C RIMS1 RIOK2 UNC13A

9.94e-04703759GO:0051640
GeneOntologyBiologicalProcesssynaptic vesicle exocytosis

UNC13B UNC13C RIMS1 UNC13A

1.12e-03125754GO:0016079
GeneOntologyBiologicalProcessactin-mediated cell contraction

CACNA1C CACNA1D SCN8A RYR2

1.19e-03127754GO:0070252
GeneOntologyBiologicalProcesscell communication involved in cardiac conduction

CACNA1C CACNA1D RYR2

1.30e-0359753GO:0086065
GeneOntologyBiologicalProcessAV node cell to bundle of His cell communication

CACNA1C RYR2

1.33e-0315752GO:0086067
GeneOntologyBiologicalProcessurinary tract smooth muscle contraction

CACNA1C TRPA1

1.33e-0315752GO:0014848
GeneOntologyBiologicalProcessestablishment of vesicle localization

UNC13B PAFAH1B1 UNC13C RIMS1 UNC13A

1.35e-03224755GO:0051650
GeneOntologyBiologicalProcesspositive regulation of membrane depolarization

CACNA1C CACNA1D

1.51e-0316752GO:1904181
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

CYC1 CACNA1C CACNA1D CACNA1S TRPA1 ALG10 SCN8A KCNAB1 RYR2 RYR3

1.80e-039227510GO:0098662
GeneOntologyBiologicalProcessspontaneous synaptic transmission

UNC13B RIMS1

1.92e-0318752GO:0098814
GeneOntologyBiologicalProcessneuromuscular junction development

UNC13B CACNA1S UNC13A

1.95e-0368753GO:0007528
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

CACNA1C CACNA1S TRPA1 PDZD8 RYR2 RYR3

1.96e-03359756GO:0006874
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol

CACNA1C CACNA1S RYR2 RYR3

1.98e-03146754GO:0051209
GeneOntologyBiologicalProcessnegative regulation of sequestering of calcium ion

CACNA1C CACNA1S RYR2 RYR3

2.03e-03147754GO:0051283
GeneOntologyBiologicalProcessvesicle localization

UNC13B PAFAH1B1 UNC13C RIMS1 UNC13A

2.06e-03247755GO:0051648
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CYC1 CACNA1C CACNA1D CACNA1S TRPA1 ALG10 SCN8A KCNAB1 RYR2 RYR3

2.11e-039427510GO:0098655
GeneOntologyBiologicalProcessregulation of sequestering of calcium ion

CACNA1C CACNA1S RYR2 RYR3

2.14e-03149754GO:0051282
GeneOntologyBiologicalProcessatrial cardiac muscle cell to AV node cell communication

CACNA1C RYR2

2.14e-0319752GO:0086066
GeneOntologyBiologicalProcessatrial cardiac muscle cell to AV node cell signaling

CACNA1C RYR2

2.14e-0319752GO:0086026
GeneOntologyBiologicalProcessatrial cardiac muscle cell action potential

CACNA1C RYR2

2.14e-0319752GO:0086014
GeneOntologyBiologicalProcesssequestering of calcium ion

CACNA1C CACNA1S RYR2 RYR3

2.35e-03153754GO:0051208
GeneOntologyBiologicalProcessactin filament-based movement

CACNA1C CACNA1D SCN8A RYR2

2.35e-03153754GO:0030048
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

UNC13B UNC13C RIMS1 UNC13A

1.28e-0623754GO:0098831
GeneOntologyCellularComponentcalcium channel complex

CACNA1C CACNA1D CACNA1S RYR2 RYR3

6.45e-0673755GO:0034704
GeneOntologyCellularComponentL-type voltage-gated calcium channel complex

CACNA1C CACNA1D CACNA1S

9.53e-0612753GO:1990454
GeneOntologyCellularComponentpresynaptic active zone

UNC13B CACNA1D SCN8A UNC13C RIMS1 UNC13A

1.16e-05141756GO:0048786
GeneOntologyCellularComponentcell cortex region

UNC13B UNC13C RIMS1 UNC13A

2.04e-0545754GO:0099738
GeneOntologyCellularComponentcation channel complex

CACNA1C CACNA1D CACNA1S SCN8A KCNAB1 RYR2 RYR3

2.15e-05235757GO:0034703
GeneOntologyCellularComponentI band

CACNA1C CACNA1D CACNA1S SCN8A RYR2 RYR3

2.93e-05166756GO:0031674
GeneOntologyCellularComponentpreribosome

RPS9 AATF XRCC5 RIOK2 FTSJ3

5.62e-05114755GO:0030684
GeneOntologyCellularComponentpresynaptic membrane

UNC13B CACNA1C CACNA1D SCN8A UNC13C RIMS1 UNC13A

6.12e-05277757GO:0042734
GeneOntologyCellularComponentZ disc

CACNA1C CACNA1D SCN8A RYR2 RYR3

2.11e-04151755GO:0030018
GeneOntologyCellularComponentsarcomere

CACNA1C CACNA1D CACNA1S SCN8A RYR2 RYR3

2.73e-04249756GO:0030017
GeneOntologyCellularComponentcalyx of Held

UNC13B UNC13C UNC13A

2.91e-0436753GO:0044305
GeneOntologyCellularComponentterminal bouton

UNC13B POLG UNC13C UNC13A

3.96e-0496754GO:0043195
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1C CACNA1D CACNA1S SCN8A KCNAB1 RYR2 RYR3

4.13e-04378757GO:0034702
GeneOntologyCellularComponentmyofibril

CACNA1C CACNA1D CACNA1S SCN8A RYR2 RYR3

4.45e-04273756GO:0030016
GeneOntologyCellularComponenttransmembrane transporter complex

CYC1 CACNA1C CACNA1D CACNA1S SCN8A KCNAB1 RYR2 RYR3

5.64e-04523758GO:1902495
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1C CACNA1D CACNA1S

6.03e-0446753GO:0005891
GeneOntologyCellularComponentsarcolemma

CACNA1C CACNA1D CACNA1S RYR2 RYR3

6.07e-04190755GO:0042383
GeneOntologyCellularComponentcontractile muscle fiber

CACNA1C CACNA1D CACNA1S SCN8A RYR2 RYR3

6.11e-04290756GO:0043292
GeneOntologyCellularComponenttransporter complex

CYC1 CACNA1C CACNA1D CACNA1S SCN8A KCNAB1 RYR2 RYR3

7.84e-04550758GO:1990351
GeneOntologyCellularComponentaxon

UNC13B CACNA1C TRPA1 RASGRF1 POLG PAFAH1B1 SCN8A KCNAB1 UNC13C UNC13A

1.27e-038917510GO:0030424
GeneOntologyCellularComponentpreribosome, small subunit precursor

RIOK2 FTSJ3

1.29e-0315752GO:0030688
GeneOntologyCellularComponentcytoplasmic region

UNC13B PAFAH1B1 KCNAB1 UNC13C RIMS1 UNC13A

1.86e-03360756GO:0099568
GeneOntologyCellularComponentsmall-subunit processome

RPS9 AATF XRCC5

2.58e-0376753GO:0032040
GeneOntologyCellularComponentpresynaptic active zone membrane

CACNA1D SCN8A RIMS1

2.78e-0378753GO:0048787
GeneOntologyCellularComponentT-tubule

CACNA1C CACNA1D CACNA1S

2.88e-0379753GO:0030315
GeneOntologyCellularComponentsarcoplasmic reticulum

CACNA1S RYR2 RYR3

3.91e-0388753GO:0016529
GeneOntologyCellularComponentcytoplasmic side of plasma membrane

ESYT3 KCNAB1 RYR2 RYR3

4.43e-03185754GO:0009898
GeneOntologyCellularComponentdistal axon

UNC13B RASGRF1 POLG PAFAH1B1 UNC13C UNC13A

4.71e-03435756GO:0150034
GeneOntologyCellularComponentsynaptic membrane

UNC13B CACNA1C CACNA1D SCN8A UNC13C RIMS1 UNC13A

4.89e-03583757GO:0097060
DomainTBC

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

3.19e-15497310SM00164
DomainRabGAP-TBC

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

7.48e-15537310PF00566
DomainTBC_RABGAP

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.11e-14557310PS50086
DomainRab-GTPase-TBC_dom

TBC1D3E TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.11e-14557310IPR000195
DomainUnc-13

UNC13B UNC13C UNC13A

5.73e-083733IPR027080
DomainVDCC_L_a1su

CACNA1C CACNA1D CACNA1S

2.29e-074733IPR005446
DomainIon_trans_dom

CACNA1C CACNA1D CACNA1S TRPA1 SCN8A RYR2 RYR3

3.06e-07114737IPR005821
DomainIon_trans

CACNA1C CACNA1D CACNA1S TRPA1 SCN8A RYR2 RYR3

3.06e-07114737PF00520
DomainMunc13_dom-2

UNC13B UNC13C UNC13A

5.70e-075733IPR014772
DomainMembr_traf_MHD

UNC13B UNC13C UNC13A

5.70e-075733PF10540
DomainMHD2

UNC13B UNC13C UNC13A

5.70e-075733PS51259
DomainMunc13_subgr_dom-2

UNC13B UNC13C UNC13A

5.70e-075733IPR019558
DomainDUF1041

UNC13B UNC13C UNC13A

5.70e-075733SM01145
DomainDUF1041

UNC13B UNC13C UNC13A

1.98e-067733PF06292
DomainMunc13_1

UNC13B UNC13C UNC13A

1.98e-067733IPR014770
DomainVDCC_a1su_IQ

CACNA1C CACNA1D CACNA1S

1.98e-067733IPR014873
DomainGPHH

CACNA1C CACNA1D CACNA1S

1.98e-067733PF16905
DomainCAPS_dom

UNC13B UNC13C UNC13A

1.98e-067733IPR010439
DomainMHD1

UNC13B UNC13C UNC13A

1.98e-067733PS51258
DomainGPHH_dom

CACNA1C CACNA1D CACNA1S

1.98e-067733IPR031649
DomainCa_chan_IQ

CACNA1C CACNA1D CACNA1S

1.98e-067733SM01062
DomainCa_chan_IQ

CACNA1C CACNA1D CACNA1S

1.98e-067733PF08763
DomainC2_dom

UNC13B ESYT3 OSBPL6 CC2D2A UNC13C RIMS1 UNC13A

3.55e-06164737IPR000008
DomainVDCCAlpha1

CACNA1C CACNA1D CACNA1S

6.74e-0610733IPR002077
DomainC2

UNC13B ESYT3 CC2D2A UNC13C RIMS1 UNC13A

1.23e-05131736PF00168
DomainC2

UNC13B ESYT3 CC2D2A UNC13C RIMS1 UNC13A

1.59e-05137736SM00239
DomainC2

UNC13B ESYT3 CC2D2A UNC13C RIMS1 UNC13A

1.95e-05142736PS50004
Domain-

UNC13B ESYT3 CC2D2A UNC13C RIMS1 UNC13A

2.46e-051487362.60.40.150
DomainRyanrecept_TM4-6

RYR2 RYR3

4.51e-053732IPR009460
DomainCAC1F_C

CACNA1C CACNA1D

4.51e-053732IPR031688
DomainRyR

RYR2 RYR3

4.51e-053732PF02026
DomainCAC1F_C

CACNA1C CACNA1D

4.51e-053732PF16885
DomainRyanodine_rcpt

RYR2 RYR3

4.51e-053732IPR003032
DomainRR_TM4-6

RYR2 RYR3

4.51e-053732PF06459
DomainRyan_recept

RYR2 RYR3

4.51e-053732IPR013333
DomainChannel_four-helix_dom

CACNA1C CACNA1D CACNA1S SCN8A

7.25e-0557734IPR027359
Domain-

CACNA1C CACNA1D CACNA1S SCN8A

7.25e-05577341.20.120.350
DomainC1_1

UNC13B PDZD8 UNC13C UNC13A

7.25e-0557734PF00130
DomainZF_DAG_PE_1

UNC13B PDZD8 UNC13C UNC13A

1.14e-0464734PS00479
DomainZF_DAG_PE_2

UNC13B PDZD8 UNC13C UNC13A

1.14e-0464734PS50081
DomainC1

UNC13B PDZD8 UNC13C UNC13A

1.21e-0465734SM00109
DomainPE/DAG-bd

UNC13B PDZD8 UNC13C UNC13A

1.29e-0466734IPR002219
DomainRIH_assoc

RYR2 RYR3

2.24e-046732PF08454
DomainRIH_assoc-dom

RYR2 RYR3

2.24e-046732IPR013662
DomainRIH_dom

RYR2 RYR3

2.24e-046732IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

2.24e-046732IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

2.24e-046732IPR015925
Domain-

RYR2 RYR3

2.24e-0467321.25.10.30
DomainRYDR_ITPR

RYR2 RYR3

2.24e-046732PF01365
DomainIns145_P3_rec

RYR2 RYR3

2.24e-046732PF08709
DomainMIR

RYR2 RYR3

6.64e-0410732PS50919
DomainMIR

RYR2 RYR3

6.64e-0410732PF02815
DomainMIR

RYR2 RYR3

6.64e-0410732SM00472
DomainMIR_motif

RYR2 RYR3

6.64e-0410732IPR016093
DomainRas_G-nucl-exch_fac_CS

RASGRF1 SOS2

1.33e-0314732IPR019804
DomainRasGEFN

RASGRF1 SOS2

2.74e-0320732SM00229
DomainRasGEF_N

RASGRF1 SOS2

3.02e-0321732PF00618
DomainRas-like_Gua-exchang_fac_N

RASGRF1 SOS2

3.31e-0322732IPR000651
DomainRASGEF_NTER

RASGRF1 SOS2

3.31e-0322732PS50212
PathwayWP_17Q12_COPY_NUMBER_VARIATION_SYNDROME

TBC1D3E TBC1D3 TBC1D3H TBC1D3L AATF TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K

1.46e-11996210M46448
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1C CACNA1S RYR2 RYR3

1.09e-0711624M47958
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1C CACNA1D CACNA1S

1.61e-066623M47762
PathwayKEGG_CARDIAC_MUSCLE_CONTRACTION

CYC1 CACNA1C CACNA1D CACNA1S RYR2

2.45e-0579625M17673
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004

CACNA1C CACNA1D CACNA1S

2.85e-0514623M47692
PathwayWP_SYNAPTIC_VESICLE_PATHWAY

UNC13B UNC13C RIMS1 UNC13A

7.26e-0551624M39457
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1C CACNA1D CACNA1S

1.35e-0423623M47666
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1C CACNA1D CACNA1S

1.74e-0425623M47948
PathwayREACTOME_CARDIAC_CONDUCTION

CACNA1C HIPK1 SCN8A RYR2 RYR3

2.62e-04130625M27454
PathwayWP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY

CACNA1C CACNA1D CACNA1S RYR2

3.10e-0474624M39462
PathwayKEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC

CACNA1C CACNA1D CACNA1S RYR2

3.10e-0474624M16376
PathwayWP_ALZHEIMERS_DISEASE

CACNA1C CACNA1D CACNA1S RYR3

3.10e-0474624MM15962
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CACNA1C CACNA1D CACNA1S RYR2 RYR3

4.62e-04147625MM15854
PathwayKEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM

CACNA1C CACNA1D CACNA1S RYR2

4.81e-0483624M8728
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CACNA1C CACNA1D CACNA1S RYR2 RYR3

5.22e-04151625M39329
PathwayKEGG_DILATED_CARDIOMYOPATHY

CACNA1C CACNA1D CACNA1S RYR2

6.53e-0490624M835
PathwayKEGG_ALZHEIMERS_DISEASE

CYC1 CACNA1C CACNA1D CACNA1S RYR3

8.03e-04166625M16024
PathwayREACTOME_NCAM1_INTERACTIONS

CACNA1C CACNA1D CACNA1S

8.23e-0442623M7169
PathwayKEGG_GNRH_SIGNALING_PATHWAY

CACNA1C CACNA1D CACNA1S SOS2

1.01e-03101624M1979
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1C CACNA1D CACNA1S RYR2 RYR3

1.10e-03178625M2890
PathwayWP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING

RYR2 RYR3

1.44e-0313622M39589
Pubmed

TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.54e-3011761116863688
Pubmed

An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.

UNC13B UNC13C RIMS1 UNC13A

1.05e-10576434706221
Pubmed

DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

TBC1D3E TBC1D3 TBC1D3H TBC1D3D TBC1D3G TBC1D3B TBC1D3F

2.87e-107476716625196
Pubmed

Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.

UNC13B UNC13C RIMS1 UNC13A

7.33e-10776436398873
Pubmed

Molecular and functional architecture of striatal dopamine release sites.

UNC13B UNC13C RIMS1 UNC13A

6.87e-091176434767769
Pubmed

Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.

CACNA1C CACNA1D CACNA1S

1.00e-08376317289261
Pubmed

The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.

UNC13B UNC13C UNC13A

1.00e-08376323658173
Pubmed

Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).

CACNA1C CACNA1D CACNA1S

1.00e-08376317767505
Pubmed

Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.

CACNA1C CACNA1D CACNA1S

1.00e-0837632173707
Pubmed

Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.

UNC13B UNC13C UNC13A

1.00e-08376333105896
Pubmed

Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.

UNC13B UNC13C UNC13A

1.00e-08376322966208
Pubmed

Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.

UNC13B UNC13C UNC13A

1.00e-08376315988013
Pubmed

PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.

TBC1D3 TBC1D3D TBC1D3F

4.00e-08476312359748
Pubmed

Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.

CACNA1C CACNA1D CACNA1S

4.00e-08476320937870
Pubmed

Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes.

TBC1D3 TBC1D3D TBC1D3F

4.00e-0847638406013
Pubmed

The Tre2 (USP6) oncogene is a hominoid-specific gene.

TBC1D3 TBC1D3D TBC1D3C

1.00e-07576312604796
Pubmed

Human TRE17 oncogene is generated from a family of homologous polymorphic sequences by single-base changes.

TBC1D3 TBC1D3D TBC1D3F

1.00e-0757638471161
Pubmed

A Trio of Active Zone Proteins Comprised of RIM-BPs, RIMs, and Munc13s Governs Neurotransmitter Release.

UNC13B RIMS1 UNC13A

1.00e-07576332755572
Pubmed

RIM, Munc13, and Rab3A interplay in acrosomal exocytosis.

UNC13B RIMS1 UNC13A

1.00e-07576322248876
Pubmed

Disentangling the Roles of RIM and Munc13 in Synaptic Vesicle Localization and Neurotransmission.

UNC13B RIMS1 UNC13A

1.00e-07576333139401
Pubmed

Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons.

CACNA1C CACNA1D RYR2

1.00e-07576331663850
Pubmed

Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.

UNC13B UNC13C UNC13A

1.00e-07576326575293
Pubmed

Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.

UNC13B UNC13C RIMS1 UNC13A

3.03e-072676417124501
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1C CACNA1D CACNA1S

3.49e-07776312900400
Pubmed

Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.

UNC13B UNC13C UNC13A

5.57e-07876325609709
Pubmed

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.

CACNA1C RYR2 RYR3

5.57e-07876311784029
Pubmed

The synaptic vesicle cycle.

UNC13B UNC13C RIMS1 UNC13A

6.33e-073176415217342
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1C CACNA1D CACNA1S SCN8A KCNAB1 RYR2

6.35e-0713976616985003
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1C CACNA1D RYR2 RYR3

1.47e-063876430786075
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

CACNA1C RYR2 RYR3

2.17e-061276319095005
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

CACNA1C CACNA1D SCN8A KCNAB1

2.93e-064576425979088
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1C CACNA1D CACNA1S

4.48e-061576320188150
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1C CACNA1D CACNA1S

4.48e-061576324453333
Pubmed

Maurocalcin and its analog MCaE12A facilitate Ca2+ mobilization in cardiomyocytes.

CACNA1D RYR2

4.71e-06276233034621
Pubmed

Temporal expression of calcium channel subunits in satellite cells and bone marrow mesenchymal cells.

CACNA1C CACNA1S

4.71e-06276225277766
Pubmed

Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.

CACNA1C CACNA1D

4.71e-06276220014384
Pubmed

Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels.

CACNA1C CACNA1D

4.71e-06276230001160
Pubmed

Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.

UNC13B UNC13A

4.71e-06276212070347
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

4.71e-06276221531043
Pubmed

Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.

CACNA1C CACNA1D

4.71e-06276221352396
Pubmed

Regulation of insulin exocytosis by Munc13-1.

UNC13B UNC13A

4.71e-06276212871971
Pubmed

A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice.

CACNA1C CACNA1S

4.71e-0627621281468
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

4.71e-06276216678258
Pubmed

Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity.

UNC13B UNC13A

4.71e-06276217561838
Pubmed

Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors.

UNC13B UNC13A

4.71e-06276223070049
Pubmed

Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells.

CACNA1C CACNA1D

4.71e-06276221054386
Pubmed

Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.

CACNA1C CACNA1D

4.71e-06276217409250
Pubmed

Neuronal L-type calcium channels open quickly and are inhibited slowly.

CACNA1C CACNA1D

4.71e-06276216267232
Pubmed

Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.

UNC13B UNC13A

4.71e-06276228489077
Pubmed

The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function.

CACNA1C CACNA1D

4.71e-06276224996399
Pubmed

Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.

UNC13B UNC13A

4.71e-06276210440375
Pubmed

Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.

UNC13B UNC13A

4.71e-06276222066784
Pubmed

Munc13-1 is required for presynaptic long-term potentiation.

UNC13B RIMS1

4.71e-06276221849565
Pubmed

Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses.

UNC13B UNC13A

4.71e-06276232187536
Pubmed

Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.

UNC13B UNC13A

4.71e-06276228772123
Pubmed

Skeletal and cardiac ryanodine receptors bind to the Ca(2+)-sensor region of dihydropyridine receptor alpha(1C) subunit.

CACNA1C RYR2

4.71e-06276211576544
Pubmed

Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.

UNC13B UNC13A

4.71e-06276217267576
Pubmed

Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of glucose-stimulated insulin secretion in mouse islets.

UNC13B UNC13A

4.71e-06276222814762
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

4.71e-0627628898078
Pubmed

An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.

CACNA1C CACNA1D

4.71e-06276224086669
Pubmed

Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons.

CACNA1C CACNA1D

4.71e-06276224849370
Pubmed

Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release.

UNC13B UNC13A

4.71e-06276228426965
Pubmed

RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone.

UNC13B RIMS1

4.71e-06276211797009
Pubmed

Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.

CACNA1C CACNA1D

4.71e-06276226049024
Pubmed

Endogenous cardiac Ca2+ channels do not overcome the E-C coupling defect in immortalized dysgenic muscle cells: evidence for a missing link.

CACNA1C CACNA1S

4.71e-0627627635187
Pubmed

Genetic interactions found between calcium channel genes modulate amyloid load measured by positron emission tomography.

CACNA1C RYR3

4.71e-06276224026422
Pubmed

Divide and conquer: an L-type voltage-gated calcium channel subtype finds a role in conditioned fear.

CACNA1C CACNA1D

4.71e-06276217015854
Pubmed

A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution.

UNC13B UNC13A

4.71e-06276235613050
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

4.71e-06276214550562
Pubmed

Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.

UNC13B UNC13A

4.71e-06276223770256
Pubmed

Membrane bridging by Munc13-1 is crucial for neurotransmitter release.

UNC13B UNC13A

4.71e-06276230816091
Pubmed

Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.

CACNA1C CACNA1D

4.71e-06276219225208
Pubmed

Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.

CACNA1C CACNA1D

4.71e-06276216706838
Pubmed

[The expression of genes encoding the voltage-dependent L-type Ca2+ channels in proliferating and differentiating C2C12 myoblasts of mice].

CACNA1D CACNA1S

4.71e-06276221789999
Pubmed

Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.

CACNA1C CACNA1D

4.71e-06276223761887
Pubmed

Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.

UNC13B UNC13C

4.71e-06276222674279
Pubmed

Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.

CACNA1C CACNA1D

4.71e-06276214981074
Pubmed

CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.

CACNA1C CACNA1D

4.71e-06276225292336
Pubmed

A common molecular basis for membrane docking and functional priming of synaptic vesicles.

UNC13B UNC13A

4.71e-06276219558619
Pubmed

Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C.

UNC13B UNC13A

4.71e-06276218701688
Pubmed

Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle.

CACNA1C CACNA1D

4.71e-06276217526649
Pubmed

Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.

CACNA1D CACNA1S

4.71e-06276228978442
Pubmed

Ligand-activated signal transduction in the 2-cell embryo.

CACNA1C CACNA1D

4.71e-06276212606379
Pubmed

Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.

CACNA1C CACNA1D

4.71e-06276224941892
Pubmed

Calcium-Independent Exo-endocytosis Coupling at Small Central Synapses.

UNC13B UNC13A

4.71e-06276231851910
Pubmed

Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.

CACNA1C CACNA1D

4.71e-06276224848473
Pubmed

Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.

CACNA1C CACNA1D

4.71e-06276222826131
Pubmed

Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.

UNC13B UNC13A

4.71e-06276211832228
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

4.71e-06276214985349
Pubmed

Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.

CACNA1C CACNA1D

4.71e-06276224470632
Pubmed

Munc13 controls the location and efficiency of dense-core vesicle release in neurons.

UNC13B UNC13A

4.71e-06276223229896
Pubmed

Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs.

UNC13B UNC13A

4.71e-06276211792326
Pubmed

Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.

CACNA1C CACNA1D

4.71e-06276224760982
Pubmed

Calcium handling precedes cardiac differentiation to initiate the first heartbeat.

CACNA1C CACNA1D RYR2

6.67e-061776327725084
Pubmed

Sorcin associates with the pore-forming subunit of voltage-dependent L-type Ca2+ channels.

CACNA1C CACNA1S

1.41e-0537629668070
Pubmed

The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.

CACNA1C CACNA1D

1.41e-05376219351867
Pubmed

Munc13- and SNAP25-dependent molecular bridges play a key role in synaptic vesicle priming.

UNC13B UNC13A

1.41e-05376237343100
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR2 RYR3

1.41e-05376218403125
Pubmed

Truncation of murine CaV1.2 at Asp-1904 results in heart failure after birth.

CACNA1C CACNA1D

1.41e-05376221832054
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR2 RYR3

1.41e-05376218434746
CytobandEnsembl 112 genes in cytogenetic band chr17q12

TBC1D3E TBC1D3 TBC1D3H TBC1D3L TBC1D3D AATF TBC1D3I TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.26e-171497612chr17q12
Cytoband17q12

TBC1D3 TBC1D3H AATF TBC1D3C TBC1D3B TBC1D3F

1.67e-089976617q12
Cytoband3q26.1

KCNAB1 WDR49

9.94e-04287623q26.1
GeneFamilyUNC13 homologs

UNC13B UNC13C UNC13A

5.75e-084453836
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

1.81e-053452287
GeneFamilyCalcium voltage-gated channel subunits

CACNA1C CACNA1D CACNA1S

3.60e-0526453253
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 30-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

2.59e-1190749PCBC_ratio_MESO-15_vs_MESO-30_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-reprogram_OSKM-L_vs_Endoderm Differentiated Cells-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TRPA1 TBC1D3H TBC1D3L SLC35F3 TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.92e-102137411PCBC_ratio_DE_from-OSKM-L_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasEndoderm Differentiated Cells-method_mRNA_vs_Endoderm Differentiated Cells-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TRPA1 TBC1D3H TBC1D3L SLC35F3 TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.92e-102137411PCBC_ratio_DE_from-mRNA_vs_DE_from-ESC_cfr-2X-p05
CoexpressionAtlasDE cord blood_vs_DE blastocyst-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TRPA1 TBC1D3H TBC1D3L SLC35F3 TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

7.46e-102427411PCBC_ratio_DE cord blood_vs_DE blastocyst_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D FHOD1 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

4.78e-082817410PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D FHOD1 TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

4.78e-082817410PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TBC1D3H TBC1D3L TBC1D3D TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.68e-06320749PCBC_ratio_MESO-5_vs_DE_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05

TBC1D3 TRPA1 TBC1D3H TBC1D3L SLC35F3 TBC1D3D PCNX4 XPA TBC1D3G TBC1D3C TBC1D3B TBC1D3K TBC1D3F

1.58e-0411537413PCBC_ratio_MESO-5_vs_SC_cfr-2X-p05
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF1 SCN8A NAP1L2 UNC13C RIMS1 RYR2

8.17e-071877667b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

CACNA1C KCNAB1 UNC13C RIMS1 RYR2 RYR3

8.43e-0718876634e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C CACNA1D SLC35F3 SCN8A RIMS1 RYR2

1.07e-06196766676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C CACNA1D SCN8A OSBPL6 RIMS1 RYR2

1.14e-06198766c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C SCN8A OSBPL6 RIMS1 UNC13A RYR2

1.14e-061987668ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C CACNA1D SCN8A OSBPL6 RIMS1 RYR2

1.14e-061987664ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CACNA1C CACNA1D SLC35F3 SCN8A RIMS1 RYR2

1.21e-0620076648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF1 CAMKV SCN8A UNC13A RYR2

1.99e-05193765be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF1 CAMKV SCN8A UNC13A RYR2

1.99e-051937650c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF1 CAMKV SCN8A UNC13A RYR2

1.99e-051937658689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C CACNA1D FHOD1 UNC13C RYR2

2.04e-0519476535f132cc38ac133be01834ed0946188aa0757eb4
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13B CACNA1C RIMS1 UNC13A RYR2

2.09e-051957652e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F3 RASGRF1 CAMKV NAP1L2 UNC13A

2.09e-05195765ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C CACNA1D SCN8A RIMS1 RYR2

2.25e-051987656d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C CACNA1D SCN8A RIMS1 RYR2

2.25e-051987650ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMKV SCN8A UNC13C RIMS1

8.91e-051377644dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMKV SCN8A UNC13C RIMS1

8.91e-05137764c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCellLPS-IL1RA-Myeloid_granulocytic-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SELL KCNAB1 UNC13C RIMS1

1.40e-0415476443735f7c58cac51855ded486ee8d8729a1b9909e
ToppCellLPS-IL1RA-Myeloid_granulocytic|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SELL KCNAB1 UNC13C RIMS1

1.40e-04154764d55fb73461885e1e02061a344ff89624ef4de487
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELL EP400 TAGAP CC2D2A

1.51e-04157764d8e283414a770f05d71f0455d0822e9a9660b115
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELL EP400 TAGAP CC2D2A

1.51e-04157764165e98bf944572cafbc06ef43c9eab7bd6bea1c2
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

CACNA1C NAP1L2 ABCA9 RYR2

1.58e-041597643f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

CACNA1C KCNAB1 RYR2 RYR3

1.66e-0416176464891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TAGAP SMC6 CCDC191 JMJD1C

1.74e-041637646bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

CACNA1C NAP1L2 ABCA9 RYR2

1.78e-041647642ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCell343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CACNA1D OSBPL6 HFM1 RYR3

2.09e-041717644ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TAGAP SMC6 CCDC191 JMJD1C

2.18e-04173764d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

CACNA1C KCNAB1 RYR2 RYR3

2.18e-04173764a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellASK428-Immune-B_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SELL FCGR1A SMC6 RIMS1

2.23e-04174764b5a7a612a515736cf3489afd0f6ad2054d54526f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

UNC13C CCDC168 IL1RAP RYR3

2.23e-04174764ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAFAH1B1 JMJD1C ABCA9 RYR2

2.33e-04176764749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1C SLC35F3 SCN8A UNC13A

2.38e-041777648abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

SELL CACNA1C ABCA9 RYR2

2.49e-04179764e4224b2e9c4ae7da62cf670adf811f4112c7d060
ToppCellLPS-IL1RA-Myeloid-Neutrophils-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SELL FCGR1A TAGAP IL1RAP

2.54e-04180764c0c07937839652e01df10cc1e70aa005800ea6f6
ToppCellLPS-IL1RA-Myeloid-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SELL FCGR1A TAGAP IL1RAP

2.54e-04180764079c199425dd3c220f03c6dca1823946f07580a1
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C TRPA1 KCNAB1 RIMS1

2.59e-0418176433cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C TRPA1 KCNAB1 ABCA9

2.65e-04182764fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellLPS-IL1RA-Myeloid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SELL FCGR1A TAGAP IL1RAP

2.82e-041857649b5fd87ea9d05e051ff1251578ecfbe5e8652853
ToppCelldroplet-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELL RPS9 SMC6 JMJD1C

2.88e-0418676426f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCellCOVID-19_Convalescent-PLT_4|World / Disease Group and Platelet Clusters

PAFAH1B1 AATF CEP295 JMJD1C

2.88e-041867645954a1e3ffafb33f2a9bc87af3343f304fda4c92
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELL CAMKV SCN8A RYR2

2.88e-041867647278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

CACNA1C CACNA1D FHOD1 RYR2

2.94e-04187764e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

CACNA1C CACNA1D ABCA9 RYR2

2.94e-0418776492d468dde81125d51daf7abd4703741abe1ab91c
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC35F3 SCN8A RIMS1 UNC13A

3.00e-04188764c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

KCNAB1 UNC13C RIMS1 RYR3

3.06e-041897646b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F3 CAMKV KCNAB1 RYR3

3.06e-04189764851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F3 CAMKV KCNAB1 RYR3

3.06e-041897643e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F3 CAMKV KCNAB1 RYR3

3.12e-041907641c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

CACNA1C CACNA1D ABCA9 RYR2

3.12e-041907643a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

RASGRF1 SCN8A UNC13A RYR2

3.12e-04190764416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SELL TAGAP CC2D2A JMJD1C

3.18e-0419176447156e5f1d790707f42f6283104a44b33af613e5
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C CACNA1D ABCA9 RYR2

3.18e-041917646688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C CACNA1D ABCA9 RYR2

3.24e-0419276499ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP PDZD8 JMJD1C ABCA9

3.31e-0419376406b65110db974f4ef90d3511ff34428976a52c9c
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CAMKV SCN8A NAP1L2 UNC13A

3.31e-04193764b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP PDZD8 JMJD1C ABCA9

3.31e-041937649c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

CACNA1C CACNA1D UNC13C RYR2

3.31e-04193764acad568621ed677031797b8c2e34dafea798d681
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP PDZD8 JMJD1C ABCA9

3.31e-04193764a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TAGAP PDZD8 JMJD1C ABCA9

3.31e-04193764b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C CACNA1D ABCA9 RYR2

3.31e-0419376499525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF1 SCN8A UNC13C RIMS1

3.31e-041937645fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA1C CACNA1D ABCA9 RYR2

3.31e-04193764e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

CACNA1C CACNA1D ABCA9 RYR2

3.31e-04193764ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C CACNA1D ABCA9 RYR2

3.37e-04194764e93de9428c986b8943fc169258847c650cfab0e5
ToppCellControl-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

CACNA1C CACNA1D ABCA9 RYR2

3.37e-041947643c2266772c5b56e8e02a461e5193e29588028ee9
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C CACNA1D UNC13C RYR2

3.37e-04194764011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SELL TAGAP IL1RAP JMJD1C

3.37e-04194764607b5d194ba56efa9b106f10f89368fc103712a0
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SELL TAGAP IL1RAP JMJD1C

3.37e-04194764744fd4580942183a1058717d0c3ac86483e366ed
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SELL TAGAP IL1RAP JMJD1C

3.37e-04194764f5367072b259ae170cf0df3d4d871ab41be29d29
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SELL TAGAP IL1RAP JMJD1C

3.37e-04194764b04cbd240c59755ef7bdeb17fee3028caef6dedb
ToppCellHealthy-B_intermediate|Healthy / disease group, cell group and cell class

RASGRF1 SMC6 CCDC191 ABCA9

3.37e-04194764aabee48bf689367edae2079b4b90d253715f1097
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

CACNA1C CACNA1D ABCA9 RYR2

3.44e-0419576461c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA1C CACNA1D ABCA9 RYR2

3.44e-04195764603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

CACNA1C CACNA1D ABCA9 RYR2

3.44e-04195764aa0add081881d349099d12efca5cdee098038d4e
ToppCellHealthy-B_intermediate|World / disease group, cell group and cell class

RASGRF1 SMC6 CCDC191 ABCA9

3.44e-041957649de79e0bdd9063ae65e5edb89cc3fe6f9a8173bc
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SELL TAGAP IL1RAP JMJD1C

3.51e-04196764fe8d3f45a64323947c36b127355d5940eb56c0ca
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C CACNA1D ABCA9 RYR2

3.51e-04196764bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SELL TAGAP IL1RAP JMJD1C

3.51e-04196764526d037bb12d81f1c235c60ddc787fbad0bbad77
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C CACNA1D ABCA9 RYR2

3.51e-041967647d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellcritical-Myeloid-Neutrophil|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SELL TAGAP IL1RAP JMJD1C

3.58e-04197764f1248781e71e3a158d06e9ec93eb90dc6d48bcb2
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SELL TAGAP IL1RAP JMJD1C

3.58e-041977643cd1c816bc7a57278b2ef615b69545356ab8f522
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C KCNAB1 UNC13A RYR2

3.64e-04198764f261a37dd07976548b897af86df1d1a0dc069889
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

CACNA1C CACNA1D ABCA9 RYR2

3.64e-04198764df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C CACNA1D ABCA9 RYR2

3.64e-041987643ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellmoderate-Myeloid-Neutrophil|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SELL TAGAP IL1RAP JMJD1C

3.64e-04198764a6306dac34af5783f3a734ef1eaa7a0c03267b4f
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C CACNA1D ABCA9 RYR2

3.64e-041987648f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

CACNA1C CACNA1D ABCA9 RYR2

3.64e-0419876426e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

CACNA1D UNC13C RYR2 RYR3

3.64e-041987640c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C CACNA1D ABCA9 RYR2

3.64e-04198764f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

CACNA1C CACNA1D ABCA9 RYR2

3.71e-041997644bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C CACNA1D ABCA9 RYR2

3.71e-0419976466a79732caf2f04c09b4d9832377aa01ca477677
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CACNA1D ABCA9 RYR2

3.79e-04200764cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CACNA1D ABCA9 RYR2

3.79e-04200764cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CACNA1D ABCA9 RYR2

3.79e-04200764e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CACNA1C CACNA1D ABCA9 RYR2

3.79e-04200764aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CACNA1D ABCA9 RYR2

3.79e-04200764311fab076f2ceb258e3970eb21e39344b894042a
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CACNA1D ABCA9 RYR2

3.79e-0420076434f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CACNA1C CACNA1D ABCA9 RYR2

3.79e-04200764a510deaada669e690329183e18df02870bd204b3
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CACNA1D ABCA9 RYR2

3.79e-0420076458b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CACNA1C CACNA1D ABCA9 RYR2

3.79e-04200764dd4228cbed8a4395166a6332e08d44d88bebe3b9
DrugCNS 1145

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

6.44e-1033696CID000190902
DrugIHC-64

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

6.44e-1033696CID000162753
DrugFPL 64176

CACNA1C CACNA1D CACNA1S RYR2 RYR3

6.47e-1015695CID000003423
DrugN-cyclopentyl-N-cyclobutylformamide

SELL CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

4.19e-0979697CID005287890
DrugCinildipine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

1.79e-0856696CID000002752
Drugnilvadipine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

2.73e-0860696CID000004494
DrugIAA-94

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

3.02e-0861696CID000003667
Druglercanidipine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

3.68e-0863696CID000065866
Druggallopamil

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

5.35e-0867696CID000001234
DrugAC1L2AC7

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

6.40e-0869696CID000068733
DrugCAS 298-57-7

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

9.00e-0873696CID000002761
Drugethosuximide

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

9.77e-0874696CID000003291
Drugnisoldipine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

1.34e-0778696CID000004499
Druglanthanum

CACNA1C CACNA1D CACNA1S TRPA1 RIMS1 RYR2 RYR3

1.84e-07136697CID000023926
Drugmethylcoumarin

CACNA1S AATF RYR2 RYR3

2.29e-0718694CID000007092
DrugNilvadipine

CACNA1C CACNA1D CACNA1S

2.65e-075693DB06712
DrugNisoldipine

CACNA1C CACNA1D CACNA1S

2.65e-075693DB00401
Drugmanidipine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

4.36e-0795696CID000004008
Drugisotetrandrine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

4.94e-0797696CID000005422
Drugnitrendipine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

5.25e-0798696CID000004507
Drugchloro-m-cresol

CACNA1S RYR2 RYR3

5.29e-076693CID000012008
DrugCPU-23

CACNA1C CACNA1D CACNA1S

5.29e-076693CID003036051
DrugNSC114784

CACNA1S RYR2 RYR3

5.29e-076693CID000419425
Drugisradipine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

5.91e-07100696CID000003784
Drugloperamide

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

7.89e-07105696CID000003954
Druglavendustin A

CACNA1C CACNA1D CACNA1S TRPA1 RASGRF1 RYR2 RYR3

8.69e-07171697CID000003894
DrugAmlodipine

CACNA1C CACNA1D CACNA1S

9.24e-077693DB00381
DrugIsradipine

CACNA1C CACNA1D CACNA1S

9.24e-077693DB00270
Druglamotrigine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

1.42e-06116696CID000003878
DrugNifedipine

CACNA1C CACNA1D CACNA1S

1.48e-068693DB01115
DrugNitrendipine

CACNA1C CACNA1D CACNA1S

1.48e-068693DB01054
DrugAC1NBU2S

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

1.49e-06117696CID004473765
Drugfluo-3

CACNA1C CACNA1D CACNA1S RIMS1 RYR2 RYR3

1.90e-06122696CID000104978
Drugdihydropyridine

CACNA1C CACNA1D CACNA1S TRPA1 KCNAB1 RYR2 RYR3

1.95e-06193697CID000104822
DrugCinnarizine

CACNA1C CACNA1D CACNA1S

2.21e-069693DB00568
DrugNimodipine

CACNA1C CACNA1D CACNA1S

2.21e-069693DB00393
Drugbepridil

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

2.30e-06126696CID000002351
Druggadolinium

CACNA1C CACNA1D CACNA1S TRPA1 PAFAH1B1 RYR2 RYR3

2.39e-06199697CID000023982
Drugpimozide

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

2.41e-06127696CID000016362
DrugMibefradil

CACNA1C CACNA1D CACNA1S

4.32e-0611693DB01388
DrugFelodipine

CACNA1C CACNA1D CACNA1S

4.32e-0611693DB01023
DrugDantrolene-13C3

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

5.18e-06145696CID000002951
Drugnimodipine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

5.18e-06145696CID000004497
Drugnicardipine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

5.18e-06145696CID000004473
DrugBay K 8644

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

6.30e-06150696CID000002303
Drugprocaine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

7.06e-06153696CID000004914
DrugAC1L1JG6

CACNA1C CACNA1D CACNA1S

9.47e-0614693CID000005026
Druggabapentin

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

1.25e-05169696CID000003446
Drugfelodipine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

1.25e-05169696CID000003333
DrugVerapamil

CACNA1C CACNA1D CACNA1S

1.45e-0516693DB00661
Drugriluzole

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

1.47e-05174696CID000005070
DrugAC1L9KQO

CACNA1S XRCC5 RYR2 RYR3

1.48e-0549694CID000447335
Drugpapaverine

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

1.57e-05176696CID000004680
DrugNSC7524

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

1.90e-05182696CID000005657
Drug3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol

TRPA1 RASGRF1 RPS9 XRCC5

2.18e-0554694ctd:C054649
Drugcobalt-60

MMAA CACNA1C CACNA1D CACNA1S TRPA1 XPA RYR2 RYR3

2.32e-05390698CID000061492
Drugbaclofen

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

2.49e-05191696CID000002284
DrugNSC759576

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

2.49e-05191696CID000003075
Drug2-hydroxycarbazole

RYR2 RYR3

2.71e-053692CID000093551
Drugcis-diammineplatinum(II

RYR2 RYR3

2.71e-053692CID000159790
Drug2-hydroxyheptanoic acid

RYR2 RYR3

2.71e-053692CID002750949
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR2 RYR3

2.71e-053692CID005748312
Drug8N3-cADPR

RYR2 RYR3

2.71e-053692CID000127713
Drugaminodantrolene

RYR2 RYR3

2.71e-053692CID009570289
DrugEucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; PC3; HT_HG-U133A

RASGRF1 CAMKV OR1G1 TFDP3 RIMS1 SOS2

3.14e-051996963759_UP
Drugsuccinylcholine

CACNA1S AATF RYR2 RYR3

4.28e-0564694CID000005314
Drugmibefradil

CACNA1C CACNA1D CACNA1S RYR3

4.28e-0564694CID000060662
Drugphenytoin

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

5.35e-05219696CID000001775
DrugNSC-686960

CACNA1C CACNA1D

5.41e-054692CID000192816
DrugPCB74

RYR2 RYR3

5.41e-054692CID000036218
Drug148504-47-6

RYR2 RYR3

5.41e-054692CID006444275
DrugSC 38249

RYR2 RYR3

5.41e-054692CID000134834
DrugAC1L1U7A

RYR2 RYR3

5.41e-054692CID000035682
DrugAC1L1JVU

CACNA1C CACNA1D CACNA1S RYR3

6.80e-0572694CID000005229
Drug3-(1H-pyrrole-2-carboxylate

CACNA1C CACNA1D CACNA1S CAMKV RYR2 RYR3

7.54e-05233696CID000005114
DrugB 874-67

CACNA1C CACNA1D

9.00e-055692CID000195466
Drugmethyl beta-aminocrotonate

CACNA1C CACNA1D

9.00e-055692CID000084253
Drugnemadipine-A

CACNA1C CACNA1D

9.00e-055692CID002856102
DrugFura-2AM

CACNA1C CACNA1D RYR2 RYR3

9.78e-0579694CID000105091
Druglindane

CACNA1C CACNA1D CACNA1S RYR2 RYR3

1.05e-04154695CID000000727
DrugM-HN

CACNA1S RYR2 RYR3

1.13e-0431693CID000015450
Drugverapamil

CACNA1C CACNA1D CACNA1S TRPA1 KCNAB1 ABCA9 RYR2 RYR3

1.15e-04490698CID000002520
Drugremifentanil

CACNA1C CACNA1D NAP1L2

1.24e-0432693CID000060814
DrugMBED

RYR2 RYR3

1.35e-046692CID000129958
DrugAC1O528X

RYR2 RYR3

1.35e-046692CID006475857
DrugMagnesium Sulfate

CACNA1C CACNA1S

1.35e-046692DB00653
Drugvalproate

CACNA1C CACNA1D CACNA1S TRPA1 POLG RYR2 RYR3

1.54e-04381697CID000003121
DrugN-methyl-DL-aspartic acid

CACNA1C CACNA1D CACNA1S TRPA1 RASGRF1 CAMKV RIMS1 RYR2 RYR3

1.55e-04655699CID000004376
DrugAC1NUZ8M

CACNA1C CACNA1D CACNA1S RYR3

1.77e-0492694CID000073211
DrugAzumoleno

RYR2 RYR3

1.88e-047692CID000056259
DrugBr2BAPTA

RYR2 RYR3

1.88e-047692CID003081001
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR2 RYR3

1.88e-047692CID009547999
Drugmag-fura-2

CACNA1S RYR2 RYR3

1.92e-0437693CID000123839
DrugU46619

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

2.26e-04285696CID000005618
Drugindo-1

CACNA1C CACNA1D RYR2 RYR3

2.34e-0499694CID000105060
Drugdipyrone

MMAA RYR2 RYR3

2.43e-0440693CID000003110
Drug1,5-benzothiazepin-4(5H)-one

CACNA1C CACNA1D

2.50e-048692CID000358939
Drugnickel

CACNA1C CACNA1D CACNA1S TRPA1 POLG XPA RYR2 RYR3

2.59e-04552698CID000000934
DrugAC1L1DXE

CACNA1C CACNA1D CACNA1S TRPA1 RYR2 RYR3

2.92e-04299696CID000002548
Drugpyraclofos

CACNA1C CACNA1D CACNA1S KCNAB1

3.04e-04106694CID000093460
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1C CACNA1D CACNA1S

3.70e-084633DOID:0060173 (implicated_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

UNC13B UNC13C JMJD1C UNC13A RYR2 RYR3

3.83e-06195636DOID:1574 (implicated_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

1.34e-053632DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

1.34e-053632DOID:8545 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

UNC13B SCN8A KIF4B UNC13C UNC13A

2.62e-05163635DOID:1826 (implicated_via_orthology)
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CACNA1C CACNA1D CACNA1S

6.30e-0536633DOID:11723 (implicated_via_orthology)
Diseasemacrophage inflammatory protein 1b measurement

TBC1D3 AATF TBC1D3B TBC1D3F

2.08e-04136634EFO_0008219
DiseaseManic Disorder

CACNA1C CACNA1D RIMS1

4.78e-0471633C0024713
DiseaseBipolar Disorder

CACNA1C CACNA1D RASGRF1 POLG SCN8A RIMS1

5.39e-04477636C0005586
DiseaseManic

CACNA1C CACNA1D RIMS1

6.30e-0478633C0338831
DiseaseDepression, Bipolar

CACNA1C CACNA1D RIMS1

6.53e-0479633C0005587
DiseaseCCL4 measurement

TBC1D3 TBC1D3F

8.32e-0420632EFO_0004751
Diseasetrans fatty acid measurement, trans/trans-18:2 fatty acid measurement

CACNA1D RYR3

1.20e-0324632EFO_0006821, EFO_0006826

Protein segments in the cluster

PeptideGeneStartEntry
CEKTVLKRVLKELWK

UNC13A

1366

Q9UPW8
RKWACRKKTSVKRKT

ESYT3

801

A0FGR9
RWKVAAAKKLVRTVV

EP400

831

Q96L91
KVRFLKLKKERKSLW

ABCA9

851

Q8IUA7
IKRHKWSVLKSRKLA

CYC1

306

P08574
VTLKTIKKKQKHRIW

NAP1L2

341

Q9ULW6
IKKKQKHRIWGTIRT

NAP1L2

346

Q9ULW6
LEKKWTSVIRLQKKV

PAFAH1B1

51

P43034
RKEYVTVKIRKKWNS

ANKRD27

911

Q96NW4
EVKSAIRKLWRKKVT

OR4C12

291

Q96R67
KCWKRSTKEIVAIKI

HIPK1

206

Q86Z02
RAKTVLTVIKWKGEK

IL1RAP

516

Q9NPH3
KKKGWRRSSLVITTK

KCNAB1

156

Q14722
RSVLKDWRKVKKLKQ

JMJD1C

1696

Q15652
TVLLTSWTEKKQRRK

PCNX4

546

Q63HM2
DTALTRRWVTKKIKV

PDZD8

111

Q8NEN9
IAKVIWCLHTKNKKR

NRDE2

741

Q9H7Z3
RKVQRETARKSQWKK

POLG

1026

P54098
IIWLARRLKKGKKSK

SELL

351

P14151
KLLRKRSQVWKPKVI

MMAA

311

Q8IVH4
PHRKTWRKSKKTVKV

GARIN1B

6

Q96KD3
KRAKKLLRSWQKLIE

MED26

71

O95402
KKDKRVTRRWRTKSV

OSBPL6

306

Q9BZF3
VKLLVWQKSVHKLRK

FAM182B

56

Q5T319
EIKSSLRKLIWVRKI

OR1G1

296

P47890
RRTKTVKKILEPKWN

RIMS1

796

Q86UR5
SWAKKIAVKRALKSE

HFM1

1056

A2PYH4
KDRTLLKTIIKVWKE

CC2D2A

501

Q9P2K1
LKTIIKVWKEMKSLR

CC2D2A

506

Q9P2K1
AKWKKAVRVTTLMKR

CAMKV

311

Q8NCB2
EELRAIIKKIWKRTS

CACNA1C

1631

Q13936
RAIIKKIWKRTSMKL

CACNA1S

1491

Q13698
IERRRTVKAAWKIEK

CCDC191

261

Q8NCU4
NTVLWVTIRKELKRK

FCGR1A

306

P12314
EWKPTKLVKVSRKNI

KIF4B

1071

Q2VIQ3
KGVICHKRRTSKWKK

CCDC168

3566

Q8NDH2
PTKRKTVKLFWRELK

FHOD1

621

Q9Y613
KEILLKQKTWHIKAR

CEP295

136

Q9C0D2
RSKKAVWHKLLSKQR

RYR2

3581

Q92736
QKWLGKETTIKRKIV

FABP9

96

Q0Z7S8
EELRAVIKKIWKKTS

CACNA1D

1571

Q01668
SLVKIFLETRKSWRK

PIGS

536

Q96S52
REVWRVKFTLAKIRK

RPS9

41

P46781
KWVESIAKIIRRKKQ

SOS2

726

Q07890
CQLIEVKKRKKVLSW

TAGAP

46

Q8N103
KDVKKALIKVWGRKT

OR5AU1

346

Q8NGC0
ALRKELKTWKVDVVL

FTSJ3

101

Q8IY81
WRTKLRRYVAKKLKE

FTSJ3

311

Q8IY81
KQIRREISRKSKWVD

TBC1D3L

66

B9A6J9
IFRLKKTWLKVSKQT

RASGRF1

1141

Q13972
WLIKLLTRLKVRKKE

SLC35F3

381

Q8IY50
WLAIQKLRSKIHKKV

AATF

491

Q9NY61
KIKTFLSLVWKRRIL

ALG10

311

Q5BKT4
KQIRREISRKSKWVD

TBC1D3B

66

A6NDS4
KQIRREISRKSKWVD

TBC1D3H

66

P0C7X1
KRKEVVLTIIRSKRW

TRPA1

591

O75762
LRKLRKWKKSQECVS

UNC13C

181

Q8NB66
KQIRREISRKSKWVD

TBC1D3F

66

A6NER0
KKAVWHKLLSKQRKR

RYR3

3471

Q15413
KKKILVTGWERAITV

WDR49

246

Q8IV35
VIRIKKGVAWTKLKV

SCN8A

1001

Q9UQD0
RQKKISWLKERVKAF

SMC6

406

Q96SB8
KTVLKRVLKELWRVV

UNC13B

1286

O14795
KQIRREISRKSKWVD

TBC1D3E

66

A0A087X179
RKVKNKRVRVVWESI

SMCO1

111

Q147U7
IISREKKKIKWIGLT

TFDP3

176

Q5H9I0
LVKHKLIAWERTKTV

RIOK2

56

Q9BVS4
KKVKELRRAVRSSVW

XPA

221

P23025
VAKKTKDVTVWRKPS

STARD4

31

Q96DR4
KQIRREISRKSKWVD

TBC1D3D

66

A0A087WVF3
TKKIKKLEKETIIWR

TXLNG

386

Q9NUQ3
KQIRREISRKSKWVD

TBC1D3G

66

Q6DHY5
KQIRREISRKSKWVD

TBC1D3

66

Q8IZP1
DIKLTVWKRLFRKVL

TRIM50

276

Q86XT4
KQIRREISRKSKWVD

TBC1D3K

66

A0A087X1G2
SRKESWKVKSEIPKV

XRRA1

446

Q6P2D8
RVKKTWTVVDAKTLK

XRCC5

271

P13010
KQIRREISRKSKWVD

TBC1D3I

66

A0A087WXS9
KQIRREISRKSKWVD

TBC1D3C

66

Q6IPX1