Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A

1.71e-0414282GO:0031402
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN1A SCN2A

2.55e-0417282GO:0099508
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN1A SCN2A

6.04e-0426282GO:0005248
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A

6.04e-0426282GO:0031420
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC28A2 SCN1A SCN2A

1.73e-03171283GO:0015081
GeneOntologyMolecularFunctionthiolester hydrolase activity

LYPLA1 THEM4

1.97e-0347282GO:0016790
GeneOntologyMolecularFunctionsodium channel activity

SCN1A SCN2A

2.41e-0352282GO:0005272
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC28A2 SCN1A SCN2A RYR2

3.82e-03465284GO:0046873
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

NT5C2 LYPLA1 THEM4 PTPRE NOTUM

4.83e-03807285GO:0016788
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A

2.32e-0417282GO:0001518
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A

3.24e-0420282GO:0033268
GeneOntologyCellularComponentpresynaptic membrane

STX2 SCN1A SCN2A RIMS3

4.81e-04277284GO:0042734
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A

6.87e-0429282GO:0043194
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN2A

6.87e-0429282GO:0034706
GeneOntologyCellularComponentsarcolemma

SCN1A SCN2A RYR2

2.05e-03190283GO:0042383
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN2A

6.02e-05882HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN2A

6.02e-05882HP:0200048
HumanPhenoLimited neck range of motion

SCN1A SCN2A

1.18e-041182HP:0000466
HumanPhenoEpilepsia partialis continua

SCN1A SCN2A

1.41e-041282HP:0012847
HumanPhenoFocal automatism seizure

SCN1A SCN2A

1.41e-041282HP:0032898
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN2A

1.67e-041382HP:0007058
HumanPhenoAortopulmonary collateral arteries

SCN1A SCN2A

2.24e-041582HP:0031834
HumanPhenoPhotosensitive tonic-clonic seizure

SCN1A SCN2A

2.24e-041582HP:0007207
HumanPhenoFacial tics

SCN1A SCN2A

2.24e-041582HP:0011468
HumanPhenoDysgenesis of the hippocampus

SCN1A SCN2A

2.56e-041682HP:0025101
HumanPhenoComplex febrile seizure

SCN1A SCN2A

2.56e-041682HP:0011172
HumanPhenoAtypical absence status epilepticus

SCN1A SCN2A

2.90e-041782HP:0011151
HumanPhenoFocal motor status epilepticus

SCN1A SCN2A

2.90e-041782HP:0032663
HumanPhenoFocal emotional seizure with laughing

SCN1A SCN2A

2.90e-041782HP:0010821
HumanPhenoVisually-induced seizure

SCN1A SCN2A

3.26e-041882HP:0020216
HumanPhenoGeneralized non-convulsive status epilepticus without coma

SCN1A SCN2A

3.26e-041882HP:0032860
HumanPhenoFocal emotional seizure

SCN1A SCN2A

3.26e-041882HP:0025613
HumanPhenoAbnormal ankle morphology

NT5C2 SCN1A SCN2A

3.83e-0410083HP:0034673
HumanPhenoNon-convulsive status epilepticus without coma

SCN1A SCN2A

4.04e-042082HP:0032671
HumanPhenoTalipes valgus

SCN1A SCN2A

4.47e-042182HP:0004684
HumanPhenoReflex seizure

SCN1A SCN2A

4.91e-042282HP:0020207
HumanPhenoTibial torsion

SCN1A SCN2A

5.37e-042382HP:0100694
HumanPhenoFocal hemiclonic seizure

SCN1A SCN2A

6.36e-042582HP:0006813
HumanPhenoSimple febrile seizure

SCN1A SCN2A

7.43e-042782HP:0011171
HumanPhenoLimited knee extension

SCN1A SCN2A

7.43e-042782HP:0003066
HumanPhenoStatus epilepticus without prominent motor symptoms

SCN1A SCN2A

7.43e-042782HP:0031475
HumanPhenoChildhood onset

ZNF711 NT5C2 NLRP1 SCN1A SCN2A RYR2

7.66e-0493886HP:0011463
HumanPhenoFocal aware seizure

SCN1A SCN2A

7.99e-042882HP:0002349
HumanPhenoStatus epilepticus with prominent motor symptoms

SCN1A SCN2A

8.58e-042982HP:0032658
HumanPhenoProgressive gait ataxia

SCN1A SCN2A

9.19e-043082HP:0007240
HumanPhenoProgressive ataxia

SCN1A SCN2A

9.19e-043082HP:0001329
HumanPhenoCogwheel rigidity

SCN1A SCN2A

1.05e-033282HP:0002396
HumanPhenoObsessive-compulsive trait

SCN1A SCN2A

1.11e-033382HP:0008770
HumanPhenoVertigo

SCN1A SCN2A RYR2

1.16e-0314683HP:0002321
HumanPhenoGeneralized clonic seizure

SCN1A SCN2A

1.18e-033482HP:0011169
HumanPhenoCalcaneovalgus deformity

SCN1A SCN2A

1.18e-033482HP:0001848
HumanPhenoDeformed tarsal bones

SCN1A SCN2A

1.25e-033582HP:0008119
HumanPhenoLimitation of knee mobility

SCN1A SCN2A

1.25e-033582HP:0010501
HumanPhenoLimitation of neck motion

SCN1A SCN2A

1.32e-033682HP:0005986
HumanPhenoDisturbance of facial expression

SCN1A SCN2A

1.32e-033682HP:0005324
HumanPhenoAbnormal neck physiology

SCN1A SCN2A

1.32e-033682HP:0025669
HumanPhenoHyperkinetic movements

SCN1A SCN2A

1.63e-034082HP:0002487
HumanPhenoFocal non-motor seizure

SCN1A SCN2A

1.63e-034082HP:0032679
HumanPhenoFocal clonic seizure

SCN1A SCN2A

1.80e-034282HP:0002266
HumanPhenoIntellectual disability, moderate

ZNF711 SARS1 SCN1A

1.87e-0317283HP:0002342
HumanPhenoPendular nystagmus

NT5C2 SCN1A

2.07e-034582HP:0012043
HumanPhenoAtypical absence seizure

SCN1A SCN2A

2.16e-034682HP:0007270
HumanPhenoAbnormal hippocampus morphology

SCN1A SCN2A

2.35e-034882HP:0025100
HumanPhenoAbnormal morphology of the limbic system

SCN1A SCN2A

2.45e-034982HP:0007343
HumanPhenoAbnormality of the ankle

NT5C2 SCN1A SCN2A

2.57e-0319283HP:0003028
HumanPhenoBilateral tonic-clonic seizure with focal onset

SCN1A SCN2A

2.75e-035282HP:0007334
HumanPhenoBilateral tonic-clonic seizure with generalized onset

SCN1A SCN2A

2.75e-035282HP:0025190
HumanPhenoCortical dysplasia

SCN1A SCN2A

3.19e-035682HP:0002539
HumanPhenoPes valgus

SCN1A SCN2A

3.19e-035682HP:0008081
HumanPhenoAbnormality of the calcaneus

SCN1A SCN2A

3.30e-035782HP:0008364
HumanPhenoAbnormal vestibular function

SCN1A SCN2A RYR2

3.41e-0321283HP:0001751
HumanPhenoArachnoid cyst

SCN1A SCN2A

3.41e-035882HP:0100702
HumanPhenoAbnormal arachnoid mater morphology

SCN1A SCN2A

3.53e-035982HP:0100700
MousePhenodecreased paired-pulse ratio

SCN1A RYR2

1.69e-054242MP:0014253
MousePhenoabnormal paired-pulse ratio

SCN1A RYR2

5.90e-057242MP:0014252
MousePhenoventricular fibrillation

SCN1A RYR2

5.90e-057242MP:0006110
DomainNa_trans_cytopl

SCN1A SCN2A

3.24e-056282PF11933
DomainNa_trans_cytopl

SCN1A SCN2A

3.24e-056282IPR024583
DomainNa_channel_asu

SCN1A SCN2A

9.68e-0510282IPR001696
DomainNa_trans_assoc

SCN1A SCN2A

9.68e-0510282IPR010526
DomainNa_trans_assoc

SCN1A SCN2A

9.68e-0510282PF06512
DomainIon_trans_dom

SCN1A SCN2A RYR2

6.49e-04114283IPR005821
DomainIon_trans

SCN1A SCN2A RYR2

6.49e-04114283PF00520
DomainChannel_four-helix_dom

SCN1A SCN2A

3.29e-0357282IPR027359
Domain-

SCN1A SCN2A

3.29e-03572821.20.120.350
DomainIQ

SCN1A SCN2A

6.53e-0381282SM00015
DomainIQ_motif_EF-hand-BS

SCN1A SCN2A

8.00e-0390282IPR000048
DomainIQ

SCN1A SCN2A

8.52e-0393282PS50096
DomainEF-hand-dom_pair

TESC SCN1A RYR2

8.85e-03287283IPR011992
PathwayREACTOME_RIBAVIRIN_ADME

SLC28A2 NT5C2

1.78e-0411262M46429
PathwayREACTOME_RIBAVIRIN_ADME

SLC28A2 NT5C2

2.13e-0412262MM16638
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

6.25e-07228229649454
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

6.25e-07228221377452
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

6.25e-07228226311622
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

6.25e-0722821317301
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

6.25e-07228233096315
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

6.25e-07228210827969
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

6.25e-07228231439038
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

6.25e-07228215249644
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

6.25e-07228219694741
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

6.25e-07228230693367
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A

1.87e-06328223859570
Pubmed

Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.

SCN1A SCN2A

1.87e-06328219270815
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A

1.87e-06328214973256
Pubmed

Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.

SCN1A SCN2A

1.87e-06328228784306
Pubmed

Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.

SCN1A SCN2A

1.87e-06328232185219
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A

1.87e-06328218784617
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A

1.87e-06328212610651
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A

1.87e-06328217544618
Pubmed

Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.

SCN1A SCN2A

1.87e-06328232005694
Pubmed

Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.

SCN1A SCN2A

1.87e-06328225155934
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A

1.87e-06328232845893
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A

1.87e-06328228518218
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A

1.87e-06328217928448
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A

3.75e-06428221156207
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A

3.75e-06428217537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A

3.75e-06428235031483
Pubmed

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.

SCN1A SCN2A

3.75e-06428226637798
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A

3.75e-06428235801810
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A

3.75e-06428229578003
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A

3.75e-0642828974318
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A

6.24e-0652821679748
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A

6.24e-0652828812438
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A

6.24e-06528224337656
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A

9.36e-06628223652591
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A

1.31e-05728225818041
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A

2.24e-05928216382098
Pubmed

Histone demethylase KDM5C is a SAHA-sensitive central hub at the crossroads of transcriptional axes involved in multiple neurodevelopmental disorders.

ZNF711 SCN2A

2.24e-05928231691806
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A

2.24e-05928215746173
Pubmed

Common variants associated with general and MMR vaccine-related febrile seizures.

SCN1A SCN2A

2.80e-051028225344690
Pubmed

Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment.

SCN1A SCN2A

2.80e-051028220602612
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A

4.10e-051228230175250
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A

4.10e-05122828169823
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A

4.85e-051328215123669
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

SCN1A SCN2A

6.52e-05152829726281
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

NT5C2 IFI30 KATNA1 HEATR5B

2.29e-0437828434315543
Pubmed

Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).

PTPRE SCN1A

4.32e-043828222952603
Pubmed

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.

NT5C2 IFI30 SARS1 PTPRE NUP205

8.01e-0493128527432908
InteractionENOPH1 interactions

RNF41 THEM4 KATNA1

2.12e-0539283int:ENOPH1
InteractionSCN4B interactions

SCN1A SCN2A

5.19e-058282int:SCN4B
Cytoband2q24.3

SCN1A SCN2A

4.28e-05162822q24.3
Cytoband19p13.1

IFI30 OR10H3

3.98e-044828219p13.1
CytobandEnsembl 112 genes in cytogenetic band chr2q24

SCN1A SCN2A

2.74e-03127282chr2q24
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A

5.54e-0592321203
CoexpressionHE_LIM_SUN_FETAL_LUNG_C5_CD5_POS_CCL22_POS_MATURE_B_CELL

IFI30 NFKBIZ TESC THEM4 ARHGAP18 KATNA1 HEATR5B NUP205

3.30e-07666288M45778
CoexpressionAtlasBM Top 100 - thalamus

SCN1A SCN2A RIMS3

6.60e-0562273BM Top 100 - thalamus
CoexpressionAtlasBM Top 100 - cerebral cortex

SCN1A SCN2A RIMS3

1.03e-0472273BM Top 100 - cerebral cortex
CoexpressionAtlasBM Top 100 - occipital lobe

SCN1A SCN2A RIMS3

1.07e-0473273BM Top 100 - occipital lobe
CoexpressionAtlasBM Top 100 - parietal lobe

SCN1A SCN2A RIMS3

1.16e-0475273BM Top 100 - parietal lobe
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IFI30 PTPRE SCN2A RYR2

5.36e-0618628423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

IFI30 NFKBIZ ARHGAP18 PTPRE

5.59e-061882845d12afb483d028ca02b3b4215131f6128e8bcd48
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFI30 NFKBIZ TESC PTPRE

6.33e-0619428416c6fcbd36d473b883fb5361caca86eb134767ab
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

IFI30 NFKBIZ TESC PTPRE

6.33e-0619428428571cf24b8a1d0ffb716167b977d420868cc874
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFI30 NFKBIZ TESC PTPRE

6.33e-06194284de9c7c602d886d0cd8bbd1d7e7744f84df951238
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFI30 NFKBIZ TESC PTPRE

6.33e-0619428449441ca0a8fa34cb847fecbb4b809dd01d879ebb
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFI30 NFKBIZ TESC PTPRE

6.72e-06197284b4f6501c266328439cba4f174e594a6a04a252a1
ToppCellnormal_Lung-Myeloid_cells-Monocytes|normal_Lung / Location, Cell class and cell subclass

IFI30 NFKBIZ TESC PTPRE

6.72e-06197284f32f1a0455c2cfdd5f187b10f6a3fd4877874c09
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IFI30 NFKBIZ ARHGAP18 PTPRE

7.00e-061992848a7bccf76fdf0b46854750a0a6a5eade0e14e515
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFI30 NLRP1 PTPRE

1.33e-04159283cdbccb83af6220bab300dfe56443ff69f6e2043a
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SCN1A GPR149 RIMS3

1.38e-04161283b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCellnormal_Lymph_Node-Myeloid_cells-Monocytes|Myeloid_cells / Location, Cell class and cell subclass

NFKBIZ TESC PTPRE

1.43e-041632837d7f18e5c99be125e95bc180823430291b770d05
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC28A2 IFI30 PTPRE

1.46e-041642836a113191ea91d103d21c5f056b1950217688ea26
ToppCellCV-Mild-3|Mild / Virus stimulation, Condition and Cluster

ZNF711 IFI30 RIMS3

1.51e-041662835599f90fc0e15a3670b03187085eba91228390a2
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

IFI30 RNF41 RYR2

1.56e-04168283c66a61d3ec711796313a2c6d2dc39aedbfc20afd
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

IFI30 RNF41 RYR2

1.56e-0416828383b4f817d95daa15ae60668e789f97d8a3b2e6dd
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFI30 NFKBIZ PTPRE

1.73e-04174283b6e3fa995def40a8fbdfc249fe108c303931a171
ToppCelldroplet-Fat-Mat-18m-Hematologic-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NT5C2 THEM4 PTPRE

1.79e-04176283867936a20f73f638055c19c8d88834aa2cc657cf
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A RYR2

1.92e-04180283f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCellMonocytes-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

IFI30 TESC PTPRE

1.95e-04181283d8b98c3d9bef026a0a35948219027f27718ffbee
ToppCellControl-Myeloid|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IFI30 NLRP1 PTPRE

1.95e-0418128325170e5285996cc80337d5f86a0255569861ae77
ToppCellHippocampus-Neuronal-Inhibitory|Hippocampus / BrainAtlas - Mouse McCarroll V32

SCN1A GPR149 RIMS3

1.98e-04182283b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ARHGAP18 SCN2A RYR2

2.04e-04184283ba65e3972b2b8d825a2c1a9d03d092cc1afad073
ToppCellMonocytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

IFI30 TESC PTPRE

2.04e-04184283d15405bf2a121570f6044546e98927b10ecc4354
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Monocytes|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IFI30 NFKBIZ PTPRE

2.08e-0418528300a991e63e9ac6de3f48a96e3be6073f90cbb442
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A RYR2

2.11e-041862837278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-ILC2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NFKBIZ THEM4 SCN2A

2.14e-04187283dd5183d2c620b2a87253a9783b70c5df2c36c570
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A RYR2

2.14e-041872837b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCelltumor_Lung-MAST_cells-MAST|tumor_Lung / Location, Cell class and cell subclass

NFKBIZ TESC ARHGAP18

2.21e-04189283cd977962e01756b663728dae32ab9aba15bf7e22
ToppCelltumor_Lung-MAST_cells|tumor_Lung / Location, Cell class and cell subclass

NFKBIZ TESC ARHGAP18

2.21e-04189283300670be76454f197bd04f82c533579dd3671969
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINB5 TESC RYR2

2.28e-0419128360bc1f3efa7bbad5cb7944fe5e049ea79cd1745a
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A RYR2

2.35e-04193283be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellMonocytes|World / lung cells shred on cell class, cell subclass, sample id

IFI30 TESC PTPRE

2.35e-04193283d66d3927f8fbe1544b5cfa5ee91a7f4a0ef1e810
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A RYR2

2.35e-041932830c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A RYR2

2.35e-041932838689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellnormal-na-Myeloid-non-classical_monocyte-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

IFI30 NFKBIZ TESC

2.35e-04193283053adc7ed9f997b503e12239a684bb9f5896e10c
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Monocytes|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

IFI30 NFKBIZ PTPRE

2.35e-04193283ddbd8944661ac3b0b5fe63471bdc24ba05598017
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

NLRP1 SCN2A RIMS3

2.39e-04194283b6488bc3a8905e926ad298332963e1bbaf010046
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

NLRP1 SCN2A RIMS3

2.39e-041942831e1f4139ad584f493d75a9b7f1568eca4653c5a2
ToppCell368C-Myeloid-Dendritic-cDC2|368C / Donor, Lineage, Cell class and subclass (all cells)

IFI30 ARHGAP18 PTPRE

2.39e-04194283eb9656d6d2da9aa074e6f5c06d750a6f9828208a
ToppCellBLOOD--(3)_MNP-(3)_Non_classical_monocytes|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IFI30 NFKBIZ TESC

2.39e-04194283f80433c7dd7590ca8c49630d2cd018b63438fd92
ToppCellMonocytes-HP_01|World / lung cells shred on cell class, cell subclass, sample id

IFI30 TESC PTPRE

2.39e-04194283fa6a2794baa6be6298f415330ff51b26a5402571
ToppCell368C-Myeloid-Dendritic|368C / Donor, Lineage, Cell class and subclass (all cells)

IFI30 ARHGAP18 PTPRE

2.39e-041942834f88759d92ac229b1edd2d4b69b878bbf2d9b6bd
ToppCellMonocytes-Inflammatory_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

IFI30 NFKBIZ TESC

2.39e-0419428328d19105123b015f8aa25ea8e6c078f630d4ba80
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IFI30 NFKBIZ PTPRE

2.42e-04195283562e4c0e4e81f6303e57b846da71d1667fc35963
ToppCellControl-Myeloid-CD16_Mono|Control / Disease, Lineage and Cell Type

IFI30 NFKBIZ TESC

2.42e-04195283a37e75be248ff28f6647e4e690629f82c1fb7370
ToppCelldistal-Hematologic-Basophil/Mast_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NFKBIZ TESC ARHGAP18

2.42e-041952834f83449fce3717518e2acbba1a4b3bea765c0bdb
ToppCell343B-Myeloid-Monocyte|343B / Donor, Lineage, Cell class and subclass (all cells)

IFI30 NFKBIZ PTPRE

2.42e-04195283169b4952118ca5ded55de928a1cf08721cdac193
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN1A SCN2A RIMS3

2.42e-04195283787e95fb59c40bba784544b662fac37606ae1427
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IFI30 NFKBIZ PTPRE

2.42e-04195283fa8ac154e5aebc26463ff84f0ad1038095770bc6
ToppCell343B-Myeloid-Monocyte-CD14+_Monocyte|343B / Donor, Lineage, Cell class and subclass (all cells)

IFI30 NFKBIZ PTPRE

2.42e-04195283b5ee368c97113432fc8fe742654cd538558f327c
ToppCellICU-NoSEP-Myeloid-CD16_Mono|ICU-NoSEP / Disease, Lineage and Cell Type

IFI30 NFKBIZ TESC

2.46e-04196283b15abb1c5396d038bab92b048795020199370f44
ToppCellInt-URO-Myeloid-CD16_Mono|Int-URO / Disease, Lineage and Cell Type

IFI30 NFKBIZ TESC

2.46e-0419628310772fed1471974cb49155df1da46e4016192620
ToppCellcontrol-Non-classical_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IFI30 NFKBIZ TESC

2.46e-041962831d71a5be652dd3281aba4f984f6ef84c993c5f63
ToppCell368C-Myeloid-Monocyte-CD14+_Monocyte|368C / Donor, Lineage, Cell class and subclass (all cells)

IFI30 NFKBIZ PTPRE

2.46e-041962838095b3c1a87ce5c1c7dcbd951806fa564c795068
ToppCellBLOOD--(3)_Non_classical_monocytes| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IFI30 NFKBIZ TESC

2.46e-04196283b5ce99e27c9e87be52c10c022a665bf4df0e8b05
ToppCell10x5'-Lung-Myeloid_Mac-Intermediate_macrophages|Lung / Manually curated celltypes from each tissue

IFI30 NFKBIZ PTPRE

2.46e-04196283fede2c605f7581ce2ea7a284cffffa1a3970d811
ToppCell368C-Myeloid-Monocyte|368C / Donor, Lineage, Cell class and subclass (all cells)

IFI30 NFKBIZ PTPRE

2.46e-041962833b46a501590aa03e3b7e25943dd43b72ecaf8182
ToppCellMultiple_Sclerosis-Myeloid-CD16_Mono|Multiple_Sclerosis / Disease, Lineage and Cell Type

IFI30 NFKBIZ TESC

2.46e-0419628383011b56780295dff5ded57064b07dcd2f19ea26
ToppCellCOVID-19_Severe-Non-classical_Monocyte|COVID-19_Severe / disease group, cell group and cell class

IFI30 NFKBIZ TESC

2.46e-04196283af9e8f5ef9d03862f707e105857309b55595b1b9
ToppCell(3)_MNP-(3)_Monocyte|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

NFKBIZ TESC PTPRE

2.46e-0419628383af2eb1c28dfe7678d972be1d6d358c4a94731d
ToppCellMonocytes-IL1B+_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

IFI30 ARHGAP18 PTPRE

2.46e-041962837bc0735d324ac5a1661434cda4116ddd58296730
ToppCellmyeloid-CD16+_Monocyte|World / Lineage and Cell class

IFI30 NFKBIZ TESC

2.46e-04196283225c102e0a2047425a7125eba1d2359159c50409
ToppCell390C-Myeloid|390C / Donor, Lineage, Cell class and subclass (all cells)

IFI30 NFKBIZ ARHGAP18

2.46e-041962835b690062db162e9ddd1a32b1be4d10f5f99c9407
ToppCellBL-critical-LOC-Myeloid|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IFI30 NFKBIZ PTPRE

2.50e-04197283932a7fae4979b561688e6222505df0f4e510ab11
ToppCellBac-SEP-Myeloid-CD16_Mono|Bac-SEP / Disease, Lineage and Cell Type

IFI30 NFKBIZ TESC

2.50e-04197283c5056605e1a61d165adba9cbee53b7cc0d41ec98
ToppCellCOVID-19_Severe-Non-classical_Monocyte|World / disease group, cell group and cell class

IFI30 NFKBIZ TESC

2.50e-0419728360fee75b12451206bb2c07b61651a73c59ec6ade
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFI30 TESC PTPRE

2.50e-04197283c6e977adb1248957d31300312310e08238b64236
ToppCellwk_20-22-Hematologic-Myeloid-S100A12-hi_cla._mono.|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

IFI30 NFKBIZ PTPRE

2.50e-04197283e862561f61a1ae1ec858b34f8d9c9a7dc8894104
ToppCellURO-Myeloid-CD16_Mono|URO / Disease, Lineage and Cell Type

IFI30 NFKBIZ TESC

2.50e-041972830201ba77419487e75edd5ea07ad7e5cbe87757d4
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IFI30 ARHGAP18 PTPRE

2.50e-041972830c8650bde08e1317baee4793201645d86f16e15d
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-non-classical_monocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IFI30 NFKBIZ TESC

2.50e-041972831463522df1b6358cbe3b5022a3e153878e9c9e43
ToppCellnormal-na-Myeloid-classical_monocyte-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

IFI30 NFKBIZ PTPRE

2.54e-0419828358aa5041077fe17ca01c5e6da077d8008d5123ab
ToppCellHealthy-Non-classical_Monocyte|Healthy / disease group, cell group and cell class

IFI30 NFKBIZ TESC

2.54e-04198283394e5fa8998c46c6f7cd57b53f347d2029c75ae1
ToppCellnormal-na-Myeloid-non-classical_monocyte-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

IFI30 NFKBIZ TESC

2.54e-04198283d91bd26e499637949768587603cad3c03dcc56e7
ToppCellnormal-na-Myeloid|normal / PBMC cell types (v2) per disease, treatment status, and sex

IFI30 NFKBIZ PTPRE

2.54e-04198283fd8ab3de94c3dc551f28668317109656fc58e463
ToppCellPBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IFI30 NFKBIZ TESC

2.54e-041982839b47585653aaebd033c9b7bba93c7a7c35a4d60e
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFI30 NFKBIZ PTPRE

2.54e-041982836edf6c547e8a3aa2b23df4662bf59ed38caa9e5e
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFI30 NFKBIZ PTPRE

2.54e-041982834b6767bd6fd4bd43eed18fd4a34c20923fa795da
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IFI30 TESC PTPRE

2.54e-04198283b226f97c034831d75258214bed9edbad15a501b2
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN1A SCN2A RYR2

2.54e-04198283c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFI30 NFKBIZ PTPRE

2.54e-041982837015b9f5ead65937e056d746340d44d0655d6a3e
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-non-classical_monocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IFI30 NFKBIZ TESC

2.54e-04198283ad8d4ad042f06fd1afbaef903fb36e57e4d23a7c
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-non-classical_monocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IFI30 NFKBIZ TESC

2.54e-0419828311b0d021114df73a539b04f76dd7c63f1fdbdf4f
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-non-classical_monocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IFI30 NFKBIZ TESC

2.54e-041982838de49c62ab533031936db4cee50ff13b259ecc22
ToppCellPBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IFI30 NFKBIZ TESC

2.54e-041982838b5d30312bbcabc6911ff03e5028766d77203dff
ToppCellnormal_Lung-Myeloid_cells-Monocytes|Myeloid_cells / Location, Cell class and cell subclass

NFKBIZ TESC PTPRE

2.54e-04198283356d36a161e6a8c9ab1acb64a76379ef351d6afa
ToppCellHealthy-Non-classical_Monocyte|World / disease group, cell group and cell class

IFI30 NFKBIZ TESC

2.54e-041982834fd27a9fb3758c94ed9f0a726296e92b0625da44
ToppCellPBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IFI30 NFKBIZ TESC

2.54e-04198283cbbdd44dfa95370c0fbaa65ba71d86bfee0ea379
ToppCellControl-Myeloid-Non-classical_Monocyte|Control / Disease group, lineage and cell class

IFI30 NFKBIZ TESC

2.54e-04198283ae0a51e63e2751a6d9dc0c8a3852680949173523
ToppCellnormal-na-Myeloid-non-classical_monocyte|normal / PBMC cell types (v2) per disease, treatment status, and sex

IFI30 NFKBIZ TESC

2.54e-04198283f5a12861e2b8ff8309f3e4d0ad83d4f6860cc616
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFI30 NFKBIZ PTPRE

2.54e-0419828318daf83309813f914b17bd226ea8a9269a26b107
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFI30 NFKBIZ PTPRE

2.54e-0419828372c7474e084d1334a09c0a3b0f3c3137038794c8
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NFKBIZ ARHGAP18 PTPRE

2.54e-041982836b18e18ed88b6043d6a18bd0f4264ec785781e57
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN1A SCN2A RYR2

2.54e-041982836d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IFI30 NFKBIZ TESC

2.54e-041982837d8fade2583c07a33dd83057cbce08e9fc77987a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN1A SCN2A RYR2

2.54e-041982838ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPBMC-Control-Myeloid-Non-classical_Monocyte|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IFI30 NFKBIZ TESC

2.54e-041982833bc3dbd178043deadd7eef413b2761dc003abd6e
ToppCellHealthy_donor-Non-classical_Monocyte|Healthy_donor / disease group, cell group and cell class (v2)

IFI30 NFKBIZ TESC

2.54e-04198283d4eae333fa100db3ea2d4cbe7a1d6ab14816f0e2
ToppCellsevere-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IFI30 NFKBIZ PTPRE

2.54e-04198283d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
DrugSAHA; Up 200; 10uM; MCF7; HT_HG-U133A_EA

STX2 NLRP1 SERPINB5 RIMS3

5.22e-051692841000_UP
DrugTrichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

STX2 NLRP1 SERPINB5 RIMS3

5.85e-051742845572_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

STX2 NLRP1 SERPINB5 RIMS3

5.98e-051752843243_UP
DrugTrichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA

STX2 NLRP1 SERPINB5 TESC

6.11e-05176284992_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

STX2 NLRP1 SERPINB5 RIMS3

6.25e-051772846784_UP
DrugTrichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

STX2 NLRP1 SERPINB5 RIMS3

6.25e-051772845209_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

STX2 NLRP1 SERPINB5 RIMS3

6.25e-051772847324_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

STX2 NLRP1 SERPINB5 RIMS3

6.39e-051782845693_UP
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

STX2 NLRP1 SERPINB5 RIMS3

6.53e-051792846551_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

NLRP1 SERPINB5 TESC RIMS3

6.67e-051802847236_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

STX2 NLRP1 SERPINB5 RIMS3

6.81e-051812847453_UP
DrugRifabutin [72559-06-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A

STX2 NLRP1 SERPINB5 RIMS3

6.81e-051812844349_UP
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

STX2 NLRP1 SERPINB5 RIMS3

6.96e-051822846879_UP
DrugTrichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

IFI30 NLRP1 SERPINB5 RIMS3

6.96e-051822846932_UP
DrugAMN082

STX2 NLRP1

9.55e-0512282CID001894360
DrugCGP 8065

NT5C2 SARS1

9.55e-0512282CID005492311
Drugestradiol; Down 200; 0.01uM; PC3; HT_HG-U133A

ZNF711 NLRP1 SCN2A RIMS3

9.84e-051992845960_DN
DrugNSC-81150

SLC28A2 NLRP1

1.13e-0413282CID000416721
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

1.69e-057272C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

1.69e-057272C0751057
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A

2.89e-059272C3502809
DiseaseFebrile Convulsions

SCN1A SCN2A

2.89e-059272C0009952
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A

3.61e-0510272DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A

3.61e-0510272DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A

5.29e-0512272DOID:0060170 (implicated_via_orthology)
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A

6.25e-0513272C0751122
DiseaseMMR-related febrile seizures

SCN1A SCN2A

8.40e-0515272EFO_0006519
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

9.60e-0516272C0393706
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

1.22e-0418272HP_0002373
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A

1.84e-0422272DOID:2030 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

SCN1A SCN2A RIMS3

3.58e-04152273DOID:0060041 (implicated_via_orthology)
Diseaseresponse to xenobiotic stimulus

STX2 PTPRE SCN1A

6.05e-04182273GO_0009410
Diseasegeneralised epilepsy

SCN1A RYR2

1.04e-0352272EFO_0005917
Diseasecognitive behavioural therapy

NT5C2 GPR149

1.29e-0358272EFO_0007820
DiseaseEpilepsy, Cryptogenic

SCN1A SCN2A

2.56e-0382272C0086237
DiseaseAwakening Epilepsy

SCN1A SCN2A

2.56e-0382272C0751111
DiseaseAura

SCN1A SCN2A

2.56e-0382272C0236018

Protein segments in the cluster

PeptideGeneStartEntry
VTHDMDMCYGMMGSL

NT5C2

426

P49902
MEMGLACVVCRQMMV

INTS12

156

Q96CB8
EDARMIHMSMQMGNE

NUP205

416

Q92621
IVIDAMMAMMHAEQK

PTPRE

346

P23469
MMAMMHAEQKVDVFE

PTPRE

351

P23469
MMPSSACEAMVGHEM

NFKBIZ

376

Q9BYH8
LTQVMAHFEEMGMCV

NLRP1

731

Q9C000
MGMMVTMMVFHLTFC

OR10H3

156

O60404
MMMHMVVQNVVGFQS

GPR149

326

Q86SP6
MNVAQFLMHMGFDMQ

NOTUM

461

Q6P988
IECAMTMMSHIPSVM

HEATR5B

641

Q9P2D3
MECAMGDRGMQLMHA

IFI30

176

P13284
MMHSSCQQEMMDVKQ

LYPLA1

206

O75608
EEMHMPTTMEDFEMA

KATNA1

451

O75449
VVVMACENQHMGDDM

RNF41

286

Q9H4P4
VVGCMVDMNEHTMMF

RYR2

1161

Q92736
MMDKVEFVHMLNATM

SARS1

416

P49591
GRMDHKCFMGMAQIM

RIMS3

246

Q9UJD0
QMMNMEATFCMGNID

SERPINB5

196

P36952
MVFMMGVEWTDCPMV

SLC28A2

466

O43868
LHEMFMDMAMFVETQ

STX2

211

P32856
MDMAMFVETQGEMIN

STX2

216

P32856
AMCLTVFMMVMVIGN

SCN1A

966

P35498
AMMEAASVCMGQMEP

TESC

161

Q96BS2
EGFCMMCTMQAHITQ

USP42

151

Q9H9J4
IATMIDATVGMCAMM

THEM4

156

Q5T1C6
MEVAGQTMCLTVFMM

SCN2A

951

Q99250
MNVAMVMAPNLFMCH

ARHGAP18

476

Q8N392
EMMADMYNRMTSACH

TIMM10

16

P62072
RMAHTMIMQDFVAGM

ZNF711

16

Q9Y462