Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesspositive regulation of mRNA splicing, via spliceosome

RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

1.10e-0844746GO:0048026
GeneOntologyBiologicalProcesspositive regulation of mRNA processing

RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

2.15e-0849746GO:0050685
GeneOntologyBiologicalProcesspositive regulation of RNA splicing

RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

1.00e-0763746GO:0033120
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

6.96e-06129746GO:0048024
GeneOntologyBiologicalProcessregulation of mRNA processing

RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

2.21e-05158746GO:0050684
GeneOntologyBiologicalProcessregulation of RNA splicing

RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

9.98e-05207746GO:0043484
GeneOntologyCellularComponentkeratohyalin granule

FLG FLG2

1.30e-045762GO:0036457
GeneOntologyCellularComponentspliceosomal complex

RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

1.33e-04215766GO:0005681
GeneOntologyCellularComponentmale germ cell nucleus

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.73e-0486764GO:0001673
GeneOntologyCellularComponentneuron to neuron synapse

PRR12 USP6 SEMA4B NRXN1 LZTS1 ANKS1B LRP1 ADAM10

6.17e-04523768GO:0098984
GeneOntologyCellularComponentcollagen-containing extracellular matrix

FLG FRAS1 ADAMTS4 LAMA4 LTBP2 FREM3 ADAM10 CDON

6.73e-04530768GO:0062023
GeneOntologyCellularComponentgerm cell nucleus

RBMY1A1 RBMY1D RBMY1B RBMY1E

7.70e-04113764GO:0043073
GeneOntologyCellularComponentpostsynaptic density

PRR12 USP6 SEMA4B LZTS1 ANKS1B LRP1 ADAM10

1.26e-03451767GO:0014069
DomainRBM1CTR

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

4.72e-118745PF08081
DomainRBM1CTR

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

4.72e-118745IPR012604
DomainMYT1

MYT1L MYT1 ST18

5.97e-083743PF08474
DomainMyelin_TF

MYT1L MYT1 ST18

5.97e-083743IPR013681
DomainZnf_C2HC

MYT1L MYT1 ST18

1.18e-066743IPR002515
Domainzf-C2HC

MYT1L MYT1 ST18

1.18e-066743PF01530
DomainZF_CCHHC

MYT1L MYT1 ST18

2.07e-067743PS51802
DomainCalx_beta

FRAS1 ADGRV1 FREM3

3.30e-068743SM00237
DomainCalx_beta

FRAS1 ADGRV1 FREM3

4.93e-069743IPR003644
DomainCalx-beta

FRAS1 ADGRV1 FREM3

4.93e-069743PF03160
DomainFilaggrin

FLG FLG2

1.55e-052742IPR003303
DomainEGF

FRAS1 FAT1 MALRD1 NRXN1 LRP1 LAMA4 LTBP2

4.01e-05235747SM00181
DomainEGF-like_dom

FRAS1 FAT1 MALRD1 NRXN1 LRP1 LAMA4 LTBP2

5.79e-05249747IPR000742
DomainEGF

FAT1 MALRD1 NRXN1 LRP1 LTBP2

1.43e-04126745PF00008
DomainLAM_G_DOMAIN

FAT1 NRXN1 LAMA4

4.56e-0438743PS50025
DomainEGF_1

FAT1 MALRD1 NRXN1 LRP1 LAMA4 LTBP2

5.21e-04255746PS00022
DomainLaminin_G_2

FAT1 NRXN1 LAMA4

5.31e-0440743PF02210
Domain-

FAT1 NRXN1 LAMA4 ADGRV1

5.50e-04957442.60.120.200
DomainEGF-like_CS

FAT1 MALRD1 NRXN1 LRP1 LAMA4 LTBP2

5.88e-04261746IPR013032
DomainASX_HYDROXYL

FAT1 NRXN1 LRP1 LTBP2

6.68e-04100744PS00010
DomainLamG

FAT1 NRXN1 LAMA4

7.04e-0444743SM00282
DomainEGF-type_Asp/Asn_hydroxyl_site

FAT1 NRXN1 LRP1 LTBP2

8.31e-04106744IPR000152
DomainRRM_1

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

1.41e-03208745PF00076
DomainLaminin_G

FAT1 NRXN1 LAMA4

1.58e-0358743IPR001791
DomainRRM

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

1.70e-03217745SM00360
DomainConA-like_dom

FAT1 MALRD1 NRXN1 LAMA4 ADGRV1

1.77e-03219745IPR013320
DomainAT_hook

PRR12 KMT2C

1.79e-0316742PF02178
DomainRRM_dom

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

2.07e-03227745IPR000504
DomainRRM

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

2.19e-03230745PS50102
DomainEGF_3

FAT1 MALRD1 NRXN1 LRP1 LTBP2

2.41e-03235745PS50026
DomainGrowth_fac_rcpt_

FRAS1 FAT1 LRP1 LTBP2

3.42e-03156744IPR009030
DomainNucleotide-bd_a/b_plait

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

3.59e-03258745IPR012677
DomainEGF_2

FAT1 MALRD1 NRXN1 LRP1 LTBP2

4.02e-03265745PS01186
DomainMetalloPept_cat_dom

ADAMTS4 ECEL1 ADAM10

4.08e-0381743IPR024079
Domain-

ADAMTS4 ECEL1 ADAM10

4.08e-03817433.40.390.10
DomainEGF_CA

FAT1 LRP1 LTBP2

4.83e-0386743PF07645
DomainS100_CABP

FLG FLG2

5.10e-0327742PS00303
DomainS_100

FLG FLG2

5.10e-0327742PF01023
DomainAT_hook

PRR12 KMT2C

5.10e-0327742SM00384
DomainAT_hook_DNA-bd_motif

PRR12 KMT2C

5.10e-0327742IPR017956
DomainS100_Ca-bd_sub

FLG FLG2

5.48e-0328742IPR013787
DomainS100/CaBP-9k_CS

FLG FLG2

5.48e-0328742IPR001751
DomainS_100

FLG FLG2

5.48e-0328742SM01394
DomainHMGI/Y_DNA-bd_CS

PRR12 KMT2C

6.69e-0331742IPR000637
DomainEGF_Ca-bd_CS

FAT1 LRP1 LTBP2

6.74e-0397743IPR018097
DomainZINC_PROTEASE

ADAMTS4 ECEL1 ADAM10

6.94e-0398743PS00142
DomainEGF_CA

FAT1 LRP1 LTBP2

7.13e-0399743PS01187
Pubmed

A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis.

RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

6.74e-1677768269511
Pubmed

Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene.

RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

8.82e-14127769598316
Pubmed

RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts.

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

2.79e-13677515184870
Pubmed

Degeneracy in human multicopy RBM (YRRM), a candidate spermatogenesis gene.

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

9.75e-1377758875892
Pubmed

An RBM homologue maps to the mouse Y chromosome and is expressed in germ cells.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.11e-1057748817321
Pubmed

Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.11e-10577420016065
Pubmed

The role of human and mouse Y chromosome genes in male infertility.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.11e-10577411097427
Pubmed

Rapid evolution of mouse Y centromere repeat DNA belies recent sequence stability.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.11e-10577419737860
Pubmed

The behavior of the X- and Y-chromosomes in the oocyte during meiotic prophase in the B6.Y(TIR)sex-reversed mouse ovary.

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.32e-10677418239052
Pubmed

Identification of target messenger RNA substrates for mouse RBMY.

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.32e-10677418492746
Pubmed

Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist.

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.32e-10677412356914
Pubmed

Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities.

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.32e-1067749499427
Pubmed

Spatiotemporal expression pattern of Myt/NZF family zinc finger transcription factors during mouse nervous system development.

MYT1L MYT1 TBR1 ST18

3.32e-10677424214099
Pubmed

Does Rbmy have a role in sperm development in mice?

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.32e-10677415051956
Pubmed

RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway.

RBMY1A1 RBMY1D RBMY1B RBMY1E

7.73e-10777417001072
Pubmed

The roles of RNA-binding proteins in spermatogenesis and male infertility.

RBMY1A1 RBMY1D RBMY1B RBMY1E

7.73e-10777410377282
Pubmed

Y chromosome short arm-Sxr recombination in XSxr/Y males causes deletion of Rbm and XY female sex reversal.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.54e-0987747479793
Pubmed

Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.

RBMY1A1 RBMY1D RBMY1B RBMY1E

4.62e-091077410601091
Pubmed

Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.

RBMY1A1 RBMY1D RBMY1B RBMY1E

4.62e-09107749384609
Pubmed

The role of Dby mRNA in early development of male mouse zygotes.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.08e-081277420543856
Pubmed

GASZ promotes germ cell derivation from embryonic stem cells.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.56e-081377423816659
Pubmed

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing.

RBMY1A1 RBMY1C RBMY1F RBMY1B

1.56e-081377410749975
Pubmed

Absence of mDazl produces a final block on germ cell development at meiosis.

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.19e-081477414611631
Pubmed

Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.98e-081577414762062
Pubmed

Myt/NZF family transcription factors regulate neuronal differentiation of P19 cells.

MYT1L MYT1 ST18

4.17e-08477321540077
Pubmed

Loss of maternal Trim28 causes male-predominant early embryonic lethality.

RBMY1A1 RBMY1D RBMY1B RBMY1E

5.17e-081777428115466
Pubmed

Sex differences in sex chromosome gene expression in mouse brain.

RBMY1A1 RBMY1D RBMY1B RBMY1E

6.64e-081877412023983
Pubmed

Lineage-specific biology revealed by a finished genome assembly of the mouse.

ZNF703 RBMY1A1 RBMY1D RBMY1B RBMY1E

1.49e-075577519468303
Pubmed

MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.20e-072677435920200
Pubmed

Potential dual functional roles of the Y-linked RBMY in hepatocarcinogenesis.

RBMY1A1 RBMY1B

4.84e-06277232473614
Pubmed

A soluble form of the giant cadherin Fat1 is released from pancreatic cancer cells by ADAM10 mediated ectodomain shedding.

FAT1 ADAM10

4.84e-06277224625754
Pubmed

Analysis of transcriptional activity by the Myt1 and Myt1l transcription factors.

MYT1L MYT1

4.84e-06277229291346
Pubmed

Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.

LRP1 ADAM10

4.84e-06277227503326
Pubmed

De novo TBR1 mutations in sporadic autism disrupt protein functions.

FOXP2 TBR1

4.84e-06277225232744
Pubmed

Expression of filaggrin-2 protein in the epidermis of human skin diseases: a comparative analysis with filaggrin.

FLG FLG2

4.84e-06277224813994
Pubmed

Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse.

MYT1L MYT1 ST18

6.94e-061777317928203
Pubmed

An abundance of X-linked genes expressed in spermatogonia.

RBMY1A1 RBMY1D RBMY1B RBMY1E

9.21e-065977411279525
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

ZNF703 SEMA4B FOXP2 TBR1 CDON

9.24e-0612677516284245
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

FRAS1 LAMA4 FREM3 CDON

1.28e-056477422261194
Pubmed

Increased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptor.

LRP1 ADAM10

1.45e-05377230279425
Pubmed

Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding.

ADAMTS4 LRP1

1.45e-05377224474687
Pubmed

ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells.

ANKS1B LRP1

1.45e-05377238123547
Pubmed

The API2-MALT1 fusion exploits TNFR pathway-associated RIP1 ubiquitination to promote oncogenic NF-κB signaling.

MALT1 RIPK1

1.45e-05377223770847
Pubmed

Myt1 and Myt1l transcription factors limit proliferation in GBM cells by repressing YAP1 expression.

MYT1L MYT1

1.45e-05377230312684
Pubmed

Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin.

FLG FLG2

1.45e-05377223403047
Pubmed

The Gab2-MALT1 axis regulates thromboinflammation and deep vein thrombosis.

MALT1 GAB4

1.45e-05377235895897
Pubmed

GATA3 regulates FLG and FLG2 expression in human primary keratinocytes.

FLG FLG2

1.45e-05377228928464
Pubmed

Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca2+ Sensitivity of Insulin Secretion Vesicles.

MYT1L ST18

1.45e-05377229656931
Pubmed

Filaggrin and filaggrin 2 processing are linked together through skin aspartic acid protease activation.

FLG FLG2

1.45e-05377232437351
Pubmed

Expression of Fraser syndrome genes in normal and polycystic murine kidneys.

FRAS1 FREM3

1.45e-05377221993971
Pubmed

Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates.

MYT1L FOXP2 TBR1

1.56e-052277332049024
Pubmed

Segmental and restricted localization pattern of Fras1 in the developing meningeal basement membrane in mouse.

FRAS1 FREM3

2.89e-05477224101214
Pubmed

Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway.

MALT1 RIPK1

2.89e-05477211262391
Pubmed

Recurrent CNVs disrupt three candidate genes in schizophrenia patients.

MYT1L NRXN1

2.89e-05477218940311
Pubmed

Differential localization profile of Fras1/Frem proteins in epithelial basement membranes of newborn and adult mice.

FRAS1 FREM3

2.89e-05477218563433
Pubmed

Myt1 family recruits histone deacetylase to regulate neural transcription.

MYT1L MYT1

4.82e-05577215935060
Pubmed

The deubiquitinase USP10 regulates KLF4 stability and suppresses lung tumorigenesis.

USP6 USP10

4.82e-05577231748695
Pubmed

Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development.

FRAS1 FREM3

4.82e-05577217251066
Pubmed

Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.

FRAS1 FREM3

4.82e-05577217596926
Pubmed

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.

RBMY1A1 RBMY1D RBMY1B RBMY1E

6.07e-059577424029230
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

SEMA4B FRAS1 FAT1 FAM234A LRP1 LAMA4 ECEL1 LTBP2 ADAM10 FKBP11 CDON

6.59e-051201771135696571
Pubmed

Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype.

FLG FLG2

7.22e-05677227304082
Pubmed

Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1.

FRAS1 FREM3

7.22e-05677217462874
Pubmed

Segregation of ipsilateral retinal ganglion cell axons at the optic chiasm requires the Shh receptor Boc.

CDON ZIC2

1.01e-04777220053908
Pubmed

Zic2 Controls the Migration of Specific Neuronal Populations in the Developing Forebrain.

TBR1 ZIC2

1.01e-04777226269635
Pubmed

3' UTR-dependent, miR-92-mediated restriction of Tis21 expression maintains asymmetric neural stem cell division to ensure proper neocortex size.

FOXP2 TBR1

1.34e-04877224726360
Pubmed

Early estrogen-induced gene 1, a novel RANK signaling component, is essential for osteoclastogenesis.

GAB4 TEC

1.34e-04877223478294
Pubmed

Shh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina.

CDON ZIC2

1.34e-04877223678105
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYT1L KMT2C NRXN1 ERC2 ADGRV1

1.47e-0422577512168954
Pubmed

Early trigeminal ganglion afferents enter the cerebellum before the Purkinje cells are born and target the nuclear transitory zone.

FOXP2 TBR1

1.72e-04977231256239
Pubmed

Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner.

USP10 NPLOC4

1.72e-04977234739333
Pubmed

The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes.

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

2.02e-0424177512815422
Pubmed

Myelin transcription factor 1 (Myt1) of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system.

MYT1L MYT1

2.15e-04107729373037
Pubmed

Human antigen R-regulated mRNA metabolism promotes the cell motility of migrating mouse neurons.

FOXP2 TBR1

2.15e-041077232098764
Pubmed

Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors.

FOXP2 TBR1

2.15e-041077217706960
Pubmed

The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.

FRAS1 FREM3

2.15e-041077215345741
Pubmed

The fringe molecules induce endocrine differentiation in embryonic endoderm by activating cMyt1/cMyt3.

MYT1 ST18

2.15e-041077216920096
Pubmed

T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis.

RBMY1A1 RBMY1C

2.15e-041077210332027
Pubmed

Fibroblast growth factor 8 organizes the neocortical area map and regulates sensory map topography.

TBR1 ZIC2

2.63e-041177222623663
Pubmed

Regulation of radial glial survival by signals from the meninges.

LAMA4 TBR1

2.63e-041177219535581
Pubmed

ApoER2 Controls Not Only Neuronal Migration in the Intermediate Zone But Also Termination of Migration in the Developing Cerebral Cortex.

FOXP2 TBR1

2.63e-041177227909010
Pubmed

A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation.

MYT1L TBR1

2.63e-041177234614421
Pubmed

Control of antiviral innate immune response by protein geranylgeranylation.

RIPK1 TRIM31

2.63e-041177231149635
Pubmed

Developmental origin of the neuronal subtypes that comprise the amygdalar fear circuit in the mouse.

FOXP2 TBR1

3.15e-041277220484636
Pubmed

St18 specifies globus pallidus projection neuron identity in MGE lineage.

FOXP2 ST18

3.15e-041277236517477
Pubmed

Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse.

FOXP2 TBR1

3.15e-041277219150975
Pubmed

Specification of spatial identities of cerebellar neuron progenitors by ptf1a and atoh1 for proper production of GABAergic and glutamatergic neurons.

TBR1 ZIC2

3.15e-041277224695699
Pubmed

Mitotic spindle regulation by Nde1 controls cerebral cortical size.

FOXP2 TBR1

3.15e-041277215473967
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

FRAS1 GAB4 ADGRV1 NEB

3.70e-0415277434299191
Pubmed

Zbtb20 defines a hippocampal neuronal identity through direct repression of genes that control projection neuron development in the isocortex.

FOXP2 TBR1

3.71e-041377223283686
Pubmed

GIGYF1 disruption associates with autism and impaired IGF-1R signaling.

GIGYF1 TBR1

3.71e-041377235917186
Pubmed

Advancing the understanding of autism disease mechanisms through genetics.

NRXN1 TBR1

3.71e-041377227050589
Pubmed

Genetic dissection of the glutamatergic neuron system in cerebral cortex.

FOXP2 TBR1

3.71e-041377234616069
Pubmed

Fate-restricted neural progenitors in the mammalian cerebral cortex.

FOXP2 TBR1

3.71e-041377222879516
Pubmed

Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors.

FOXP2 TBR1

3.71e-041377219403657
Pubmed

Regulation of Cerebral Cortex Folding by Controlling Neuronal Migration via FLRT Adhesion Molecules.

FOXP2 TBR1

3.71e-041377228475893
Pubmed

Disruption of TCF4 regulatory networks leads to abnormal cortical development and mental disabilities.

TBR1 CDON

3.71e-041377230705426
Pubmed

Fukutin-related protein alters the deposition of laminin in the eye and brain.

LAMA4 TBR1

3.71e-041377221900571
Pubmed

The exon junction complex component Magoh controls brain size by regulating neural stem cell division.

FOXP2 TBR1

3.71e-041377220364144
Pubmed

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.

MYT1L FOXP2 TBR1

4.13e-046577326655900
InteractionC2CD4B interactions

FRAS1 FAT1 FZD3 ADGRV1 PATJ

6.05e-0744755int:C2CD4B
InteractionNXPH2 interactions

FRAS1 FAT1 NRXN1 ADGRV1

6.67e-0633754int:NXPH2
InteractionXAGE1A interactions

FRAS1 FAT1 FZD3 ADGRV1

1.61e-0541754int:XAGE1A
CytobandYq11.223

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

5.39e-0793775Yq11.223
CytobandEnsembl 112 genes in cytogenetic band chrYq11

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

1.83e-04311775chrYq11
GeneFamilyZinc fingers C2H2C-type

MYT1L MYT1 ST18

2.97e-0835731261
GeneFamilyRNA binding motif containing

RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

5.48e-05213576725
GeneFamilyEF-hand domain containing|S100 fused type protein family

FLG FLG2

2.03e-0475721350
CoexpressionCHEN_ETV5_TARGETS_TESTIS

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.38e-0633754MM701
CoexpressionZHENG_IL22_SIGNALING_DN

RBMY1A1 RBMY1D RBMY1B RBMY1E

8.43e-0645754MM763
CoexpressionACEVEDO_METHYLATED_IN_LIVER_CANCER_DN

MYT1L FLG MALT1 KMT2C RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E ADGRV1 ST18

3.68e-058737511M16009
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FAT1 NRXN1 ABCA12 ADGRV1 NEB ST18

2.44e-081847472cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FAT1 NRXN1 ABCA12 ADGRV1 NEB ST18

2.44e-08184747ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FAT1 NRXN1 ABCA12 ADGRV1 NEB ST18

2.44e-081847472b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA4B FRAS1 FOXP2 MYT1 ERC2 ADGRV1 PATJ

3.04e-0819074759bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRAS1 MYT1 ANKS1B ADGRV1 NEB ST18

3.00e-07162746bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYT1L NRXN1 LZTS1 LRP1 ERC2 ARHGEF17

3.99e-071707465570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 MALRD1 FOXP2 PARD3B PATJ FREM3

4.42e-07173746b799c06a6a5754668e789f70c0c8bc1508568575
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT1 NRXN1 ADAMTS4 LZTS1 ERC2 ARHGEF17

6.34e-07184746689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA4B FRAS1 FOXP2 MYT1 ADGRV1 PATJ

7.65e-071907461cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-PNEC-PNEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYT1L NRXN1 MYT1 BEST3 NEB ST18

7.89e-07191746146cfd4daa2878536b4f381564c787919ad855a8
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-PNEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYT1L NRXN1 MYT1 BEST3 NEB ST18

7.89e-0719174612ea07565dc0e62cade9fbab4a2d763e47a341e3
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NRXN1 MYT1 BEST3 ERC2 ADGRV1 ST18

8.13e-071927464d3a1c267739b1479217144656986972fc86db43
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

FAT1 FOXP2 ECEL1 ADGRV1 PATJ CDON

9.44e-0719774644a59dfb889577b3160a5b13ada1276771a00241
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-midbrain/hindbrain_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

MYT1L AFAP1 NRXN1 MYT1 TBR1 ST18

9.44e-07197746c7078f6fcf27319ba8c5ebe700bcae7f1e7e39c1
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FAT1 FOXP2 ANKS1B LRP1 LAMA4 LTBP2

1.00e-0619974638cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

FAT1 AFAP1 ANKS1B LRP1 LAMA4 LTBP2

1.03e-06200746a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYT1L NRXN1 MYT1 ERC2 ST18

6.85e-061597457747cef94c55144fddcd024a7495318357f1351b
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN1 RHBDL3 ANKS1B ADGRV1 ST18

7.73e-0616374599cf60dc87f7ce288553091bffcd85109a02bd8f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN1 RHBDL3 ANKS1B ADGRV1 ST18

7.73e-06163745510c0af66e82c5a8cf8edd0547dae4018a87dbbf
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RIPK1 ANKRD39 FLG2 FKBP11 CRY1

9.21e-0616974501a24a8817628125bd004b2be68ffa62c7111f6e
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L FRAS1 ABCA12 LTBP2 ADGRV1

9.21e-0616974512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellControl-Stromal-Pericyte|World / Disease state, Lineage and Cell class

ADAMTS4 LZTS1 LAMA4 ECEL1 ARHGEF17

1.00e-05172745813d4256b05b66ca11b08cc0026459d79f12c0eb
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRXN1 ADAMTS4 MYT1 ADGRV1 PATJ

1.03e-0517374523e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCellControl-Stromal-Pericyte|Control / Disease state, Lineage and Cell class

ADAMTS4 LZTS1 LAMA4 ECEL1 ARHGEF17

1.06e-0517474591fc1f1c891f105a91968c22e2de5321c52b439a
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MALT1 NPB MYT1 TRIM31 ECEL1

1.09e-051757458a37b2811f39bb9baa537e8755a29d559eb8185a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRGUK FRAS1 NRXN1 ANKS1B ADGRV1

1.15e-05177745d05497d2c80a66ec6a4e1733fea3a5534877a6a7
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MALT1 NPB MYT1 TRIM31 ECEL1

1.18e-05178745a95bb77a2c2ce7c38989e6f971812f7ee9f5bd4b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 MALRD1 PARD3B ADGRV1 PATJ

1.22e-05179745cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MYT1L NRXN1 MYT1 ECEL1 ST18

1.35e-051837459dfb398b9995d562864fe688861a831ada0814cd
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT1 ADAMTS4 LZTS1 ERC2 ARHGEF17

1.39e-05184745327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MYT1L NRXN1 MYT1 ECEL1 ST18

1.43e-05185745512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NRXN1 MYT1 BEST3 ST18 ZIC2

1.46e-05186745c7983281a290201567b398e9ea6baddb96c692bb
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYT1L NRXN1 MYT1 ERC2 ST18

1.46e-05186745b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

FRAS1 FAT1 ADGRV1 PATJ CDON

1.50e-05187745ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRAS1 ASPG ADGRV1 PATJ FREM3

1.50e-051877454ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellPCW_05-06-Neuronal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HOXD1 NRXN1 MYT1 ECEL1 ADGRV1

1.50e-0518774503a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 FOXP2 MYT1 ADGRV1 PATJ

1.50e-05187745c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT1 ADAMTS4 LZTS1 LAMA4 ARHGEF17

1.62e-051907454eb92aef1ee868f4537483d19014d947b7684612
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NRXN1 MYT1 BEST3 ADGRV1 ST18

1.62e-051907452375e604eacd38f61f3e661ba2f76d286fcceca7
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT1 ADAMTS4 LZTS1 LAMA4 ARHGEF17

1.62e-051907457be4341e2909101d756f14031c21e705eb45e69a
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NRXN1 MYT1 BEST3 ERC2 ST18

1.66e-0519174519832ddd559a353e1618fe853d79e3edfec6dcda
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L NRXN1 MYT1 ANKS1B ADGRV1

1.75e-0519374566af80f4b51e1ce97b6fb7c630dc5f95bfa7e7d4
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NRXN1 MYT1 BEST3 ADGRV1 ST18

1.75e-051937458603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYT1L NRXN1 BEST3 NEB ST18

1.75e-0519374525b1e5a04724023918c8939109a92b35582d5e5c
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT1 LZTS1 LAMA4 LTBP2 ARHGEF17

1.79e-051947452d66091097e106c7bee22e5281f50724700bdf8d
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYT1L GAB4 ADGRV1 FLG2 CDON

1.84e-05195745d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYT1L GAB4 ADGRV1 FLG2 CDON

1.84e-0519574519853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

FOXP2 ANKS1B LRP1 PARD3B LTBP2

1.84e-05195745a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L FRAS1 LZTS1 ERC2 TBR1

1.84e-05195745ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 FAT1 FOXP2 PARD3B PATJ

1.88e-05196745c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 FAT1 FOXP2 PARD3B PATJ

1.88e-051967456ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellTracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LZTS1 RHBDL3 PARD3B INVS CRY1

1.93e-051977454edf043e8f586fd375f56485841fe992a18bf853
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA4B FRAS1 FAT1 FOXP2 PATJ

1.93e-051977457e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

MYT1L NRXN1 MYT1 TBR1 ST18

1.93e-051977452d92b0483d57541aee382dda80e42cf66e813d6b
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYT1L NRXN1 MYT1 BEST3 ST18

1.98e-051987458f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-Neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

ZNF703 FZD3 ADGRV1 TBR1 VDAC3

1.98e-0519874590ebefc9ba8dc2a81471e5693384f5ce56f06298
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYT1L NRXN1 MYT1 BEST3 ST18

1.98e-05198745e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 LZTS1 LAMA4 LTBP2 ARHGEF17

2.02e-0519974520f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 LZTS1 LAMA4 LTBP2 ARHGEF17

2.02e-051997457c272a1aa7f3e931ad5d20809719d85b3bce4cb0
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FAT1 FOXP2 ECEL1 ADGRV1 PATJ

2.07e-05200745e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

FOXP2 ECEL1 TBR1 ST18 ZIC2

2.07e-05200745c792d1dbbe27ebd60f4770834f30882c1a625be5
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FAT1 ANKS1B LRP1 LAMA4 LTBP2

2.07e-0520074509537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

FAT1 ANKS1B LRP1 LAMA4 LTBP2

2.07e-05200745a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

AFAP1 MYT1 ECEL1 ST18 ZIC2

2.07e-05200745332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCellParenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT1 ADAMTS4 LZTS1 LAMA4 ARHGEF17

2.07e-05200745f9bc22ff17bb1c751e6b05bca3f403836f33459a
ToppCellParenchymal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT1 ADAMTS4 LZTS1 LAMA4 ARHGEF17

2.07e-052007450a7640db28c708003d5da2d19eb651f6fedfd710
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

MYT1L FAT1 LZTS1 LRP1 ARHGEF17

2.07e-05200745bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellThalamus|World / BrainAtlas - Mouse McCarroll V32

PPP1R3A PATJ FREM3 ZIC2

4.20e-051167445ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 FLG2 NEB ST18

8.02e-05137744dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 MYT1 ADGRV1 ST18

9.99e-0514574496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellBasal_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 NRXN1 ABCA12 LZTS1

1.29e-0415574430accc72a6a914ae0c4d52b373ea1c9a98efbf22
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|356C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS4 NPB LZTS1 CDON

1.29e-04155744e1a20e88b9c0eaf7ca7004acc0eda096d1588563
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT1 LZTS1 ERC2 ARHGEF17

1.32e-041567446365b69ede98bc866e996bc52736b00401aacf6f
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MYT1L NRIP1 FBXW8 NEB

1.36e-04157744432b8719a8afd289cf48068e12c26a349d753fcc
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 NRXN1 RHBDL3 PATJ

1.36e-041577446ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue|TCGA-Thryoid / Sample_Type by Project: Shred V9

NRXN1 FOXP2 ANKS1B ADGRV1

1.39e-041587448e48952af0831a1fc71ad422e8216b5a92a75991
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue|TCGA-Thryoid / Sample_Type by Project: Shred V9

NRXN1 FOXP2 ANKS1B ADGRV1

1.39e-04158744e5b55c15a8c99c8d7fc94949f0d3c22e0c3fee7b
ToppCellTCGA-Thryoid-Solid_Tissue_Normal|TCGA-Thryoid / Sample_Type by Project: Shred V9

NRXN1 FOXP2 ANKS1B ADGRV1

1.39e-0415874455214d674808584e4d48f8c5e3b8c0e206cb9bb8
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 NRXN1 FZD3 NEB

1.43e-041597444000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 NRXN1 FZD3 NEB

1.43e-041597447619d0d49738dd08daf01b42664691a5323aa793
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FOXP2 ABCA12 ADGRV1

1.46e-04160744c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MALRD1 FOXP2 ZNF862 ADGRV1

1.46e-0416074403b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FOXP2 ABCA12 ADGRV1

1.46e-0416074425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA4 FLG2 CDON

1.50e-04161744a006491c991e6a134be20ad75092a91f3b7c3c91
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 AFAP1 ECEL1 FREM3

1.53e-0416274457d627259d27f39885bf416d74bcb6656db6e27b
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS4 LZTS1 RHBDL3 ARHGEF17

1.57e-041637448f24cef152f5965727bbeee116bd26c75cbba82a
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYT1L NRXN1 BEST3 ST18

1.61e-04164744be49af6335f2505065cde2cb9800e4a5516811b1
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MALT1 SEMA4B ANKS1B TEC

1.68e-041667443e3e9296e6919a38602e417a6606c046af3bd101
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L ASPG BEST3 ECEL1

1.72e-041677443dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L ASPG BEST3 ECEL1

1.72e-0416774495b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MALT1 SEMA4B ANKS1B TEC

1.72e-041677443c3e1c31aacca48099693aea2efdfa22fc0e4af4
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L ASPG BEST3 ECEL1

1.72e-041677449480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRAS1 NRXN1 MYT1 ECEL1

1.72e-0416774449b19159c62d33d65ed1e59a148c11ae902fd41c
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-Zbtb32+_B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MALT1 SEMA4B ANKS1B TEC

1.72e-0416774477a4d7ce44847c76074d4f5340d61b398fe43e6c
ToppCellControl|World / group, cell type (main and fine annotations)

ANKS1B PARD3B ADGRV1 PATJ

1.76e-04168744a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellP28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KMT2C ERC2 PATJ ARHGEF17

1.76e-041687448c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCellASK440-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

FZD3 ANKS1B FKBP11 ST18

1.76e-04168744127559d1a083c68cda9fce143afcc3eec168df17
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

SEMA4B FAM234A ZNF862 NEB

1.80e-04169744dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYT1L NRXN1 BEST3 ST18

1.80e-04169744b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

FRAS1 FAT1 ADGRV1 PATJ

1.84e-04170744269dee5abca9f6aa079f116f0d8f1d198604d9d4
Drughydantoin-5-propionic acid

RBMY1A1 RBMY1D RBMY1B RBMY1E

5.58e-0721734CID000000782
DrugAZFd

RBMY1A1 RBMY1D RBMY1B RBMY1E

8.22e-0723734CID000196489
DrugVistar

RBMY1A1 RBMY1D RBMY1B RBMY1E

5.30e-0636734CID000040896
Drug2-chlorodideoxyadenosine

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.09e-0543734CID000072194
DrugPKI166

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.70e-0548734CID006918403
DrugHgCl

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.85e-0549734CID000024182
Drugazafagomine

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.38e-0557734CID011957435
DiseaseMyopia

NRIP1 FRAS1 NRXN1 LZTS1 ANKS1B ERC2 ECEL1 NPLOC4

4.06e-06385718HP_0000545
Diseasecystathionine measurement

PARD3B TEC TEC

1.26e-0519713EFO_0010474
Diseasetyrosine-protein kinase TEC measurement

TEC TEC

3.41e-054712EFO_0020830
DiseaseNeurodevelopmental Disorders

MYT1L KMT2C PARD3B TBR1

7.64e-0593714C1535926
DiseaseFEV/FEC ratio

PRR12 FRAS1 AFAP1 ANKS1B LRP1 ERC2 LTBP2 NEB ARHGEF17 NPLOC4 CDON

1.60e-0412287111EFO_0004713
DiseaseSemantic-Pragmatic Disorder

NRXN1 FOXP2

3.10e-0411712C0454655
DiseaseAuditory Processing Disorder, Central

NRXN1 FOXP2

3.10e-0411712C0751257
DiseaseLanguage Delay

NRXN1 FOXP2

3.10e-0411712C0023012
DiseaseLanguage Development Disorders

NRXN1 FOXP2

3.10e-0411712C0023014
DiseaseSpeech Delay

NRXN1 FOXP2

3.10e-0411712C0241210
Diseasesphingomyelin 18:1 measurement

LZTS1 PARD3B

4.38e-0413712EFO_0010394
Diseaseglucose-dependent insulinotropic peptide measurement, glucose tolerance test

HOXD1 ARHGEF17

5.10e-0414712EFO_0004307, EFO_0008464
DiseaseAlobar Holoprosencephaly

CDON ZIC2

5.87e-0415712C0431363
Diseaseresponse to olanzapine

ANKS1B ADGRV1

5.87e-0415712GO_0097333
DiseaseLobar Holoprosencephaly

CDON ZIC2

6.70e-0416712C0431362
DiseaseSemilobar Holoprosencephaly

CDON ZIC2

6.70e-0416712C0751617
DiseaseHoloprosencephaly

CDON ZIC2

7.58e-0417712C0079541
Diseasebody weight

MYT1L PPP1R3A NRXN1 FOXP2 ANKS1B ERC2 PARD3B LTBP2 ADGRV1 PATJ

8.45e-0412617110EFO_0004338
Diseasesquamous cell carcinoma (is_implicated_in)

KMT2C LZTS1

8.52e-0418712DOID:1749 (is_implicated_in)
Diseaseresponse to angiotensin-converting enzyme inhibitor

NRXN1 ANKS1B ERC2

8.92e-0478713EFO_0005325
Diseasecervical carcinoma

NRXN1 LZTS1 MYT1 ADGRV1

9.86e-04182714EFO_0001061
Diseasebody fat percentage

PPP1R3A NRXN1 ANKS1B LRP1 PARD3B PATJ

1.15e-03488716EFO_0007800
Diseasechronic obstructive pulmonary disease

FRAS1 AFAP1 FZD3 TRIM31 ERC2 FREM3 ARHGEF17

1.33e-03688717EFO_0000341
Diseasepulse pressure measurement

NRIP1 AFAP1 MALRD1 MYT1 LRP1 LTBP2 TEC ST18 TEC LACTB

1.77e-0313927110EFO_0005763
DiseaseAdenoid Cystic Carcinoma

KMT2C FAT1 FOXP2

1.83e-03100713C0010606
Diseaseganglion cell inner plexiform layer thickness measurement

NPLOC4 INVS

2.07e-0328712EFO_0600005
Diseasepulmonary tuberculosis

MYT1L LAMA4

2.22e-0329712EFO_1000049

Protein segments in the cluster

PeptideGeneStartEntry
HTHVNDGTEFGGSIY

VDAC3

181

Q9Y277
GGYHHDSATSILSSE

BEST3

516

Q8N1M1
EVSGHLYSGSTGHQI

FAM234A

236

Q9H0X4
HIYGEEGSFSHGSVI

ADAM10

106

O14672
GSLGHVDSHSSLVGY

ABCA12

2321

Q86UK0
GTSNGYAHPSGTALH

AFAP1

486

Q8N556
HHSGTDALYFTGLEG

ADGRV1

1321

Q8WXG9
YAHGRVSGLVVDTGH

ACTL9

186

Q8TC94
GSHYEQSVDSSGHSG

FLG

1826

P20930
GSYHEQSVDRSGHSG

FLG

3771

P20930
GGATALHRASYCGHT

ANKRD39

96

Q53RE8
ALGRDHSEHLSGSSY

RBMY1A1

376

P0DJD3
ALGRDHSEHLSGSSY

RBMY1B

376

A6NDE4
ALGRDHSEHLSGSSY

RBMY1C

376

P0DJD4
ALGRDHSEHLSGSSY

RBMY1D

376

P0C7P1
ALGRDHSEHLSGSSY

RBMY1E

376

A6NEQ0
ALGRDHSEHLSGSSY

RBMY1F

376

Q15415
SPAYHGGHSSGSDDD

ARHGEF17

266

Q96PE2
DSSGYTALHHAALNG

ANKS1B

56

Q7Z6G8
TTDGDSGIYGHVTYH

FAT1

2516

Q14517
PHSALGLGLEDYSHS

PARD3B

661

Q8TEW8
GLGLEDYSHSSGVDS

PARD3B

666

Q8TEW8
EGEEHGYSSGHSRGT

FLG2

136

Q5D862
HGQAGSHYPESGSSV

FLG2

1976

Q5D862
SSGLGDYLELHIHQG

NRXN1

136

P58400
RGLLHYAHDGSDSTS

FRAS1

1286

Q86XX4
GQDSTITHGHSYPGS

KMT2C

3571

Q8NEZ4
GSHHPDYTALSSGDL

LZTS1

76

Q9Y250
GHGHSYTTAEEAAGI

MLANA

16

Q16655
LHSDPSILGYSLHGS

GIGYF1

1011

O75420
AATSGGAGHYHSLQD

MALT1

741

Q9UDY8
HVHYATSAVFSGGGS

HOXD1

131

Q9GZZ0
GYDGHSALHVAEAAG

ASPG

531

Q86U10
LTGGLSHASDVVLYH

LRP1

4126

Q07954
HYASHTGGAVGASSV

LACTB

481

P83111
VHSHDGVVIAGYTSG

FBXW8

216

Q8N3Y1
SSHEETGASHTLYGH

FOXP2

331

O15409
LHEYGAVGGSTHTAT

NPLOC4

566

Q8TAT6
YPAGHGSASESEHRS

NRIP1

911

P48552
HHLGRSGSGTEQVYL

LRGUK

116

Q96M69
SYTDQHGGLTGSSHH

ERC2

116

O15083
SSGLGDYLELHIHQG

NRXN1

1171

Q9ULB1
HATHRDAYSGGSVDL

PSMB11

211

A5LHX3
IGTIIGHELTHGYDD

ECEL1

606

O95672
HHLTSEGSALGGITG

PPP1R3A

601

Q16821
YGTTSGSLETLSHHL

MALRD1

2141

Q5VYJ5
YSGATAASETLSGHG

ADAMTS4

761

O75173
FGDTLHIHYTGSLVD

FKBP11

56

Q9NYL4
DSSALLHPGLHYGVS

CFAP70

876

Q5T0N1
SGYSVDGVSGHIHGF

GAB4

256

Q2WGN9
FLTNGGLSSGYSHLH

CDON

1036

Q4KMG0
SQGSGILHYAHGDSQ

CRY1

531

Q16526
GDTTTLYSQGGHGHD

LTBP2

376

Q14767
GSIHSKVSSYHGSLH

FZD3

576

Q9NPG1
LAEAGGYLHTAEGTH

SLC25A35

86

Q3KQZ1
GYLHTAEGTHSPARS

SLC25A35

91

Q3KQZ1
GHSGSGHSTAYHFLS

CPHXL

231

A0A1W2PPM1
SSGTLVHGHSVNGEY

LAMA4

1681

Q16363
YGGTALHAAALSGHV

INVS

356

Q9Y283
PGSSHSGHYLGDLLL

FREM3

601

P0C091
LGHEGTEAGKHYVAS

TRIM31

206

Q9BZY9
SSSYPHSGGSELVLH

TBR1

21

Q16650
GEGSSGFRHYHIKET

TEC

291

P42680
GSSGGVYALVSAHLA

RHBDL3

276

P58872
GLHHTYDVLFLGTGD

SEMA4B

456

Q9NPR2
LSYSTGHSPALSGHG

PRR12

531

Q9ULL5
GHSSYSVGRAAGLLS

NPB

31

Q8NG41
GTAYSSAASHGNAVH

RIPK1

436

Q13546
GSGHVTGNYASHRSV

ST18

731

O60284
HPYGKSHLSTAGGLA

ZNF703

546

Q9H7S9
ESSGHGYSGSLSLLC

ZNF157

91

P51786
SFDGHHYISSIVSGG

PATJ

576

Q8NI35
YLSHLSTGSGHIEGD

ZNF862

111

O60290
SYHIALSGEAHTIGE

ZBED5

201

Q49AG3
HGNSATGGHYTTDVF

USP10

741

Q14694
YTHHGDTGVSGTHTG

WEE2

526

P0C1S8
AISCHSGILSGGHYI

USP6

1316

P35125
AALGPHAAHVGSYSG

ZIC2

96

O95409
DGSGHITGNYASHRS

MYT1L

911

Q9UL68
DGSGHITGNYASHRS

MYT1

806

Q01538
HHLSTYSDGGVFAVS

NEB

6561

P20929