Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	complement component C3b binding	CFHR1 CFHR2 CR1 CR1L	6.33e-08	12	69	4	GO:0001851
GeneOntologyMolecularFunction	complement binding	CFHR1 CFHR2 CR1 CR1L CR2	7.96e-08	32	69	5	GO:0001848
GeneOntologyMolecularFunction	opsonin binding	CFHR1 CFHR2 CR1 CR1L	1.56e-06	25	69	4	GO:0001846
GeneOntologyMolecularFunction	complement component C3b receptor activity	CR1 CR1L	1.18e-05	2	69	2	GO:0004877
GeneOntologyMolecularFunction	complement component C4b receptor activity	CR1 CR1L	1.18e-05	2	69	2	GO:0001861
GeneOntologyMolecularFunction	complement receptor activity	CR1 CR1L CR2	1.40e-05	14	69	3	GO:0004875
GeneOntologyMolecularFunction	complement component C4b binding	CR1 CR1L	3.52e-05	3	69	2	GO:0001855
GeneOntologyMolecularFunction	calcium ion binding	SELP FAM20C GJB2 FAT1 FBN1 OIT3 EGF LPCAT2 SVEP1 CEMIP2	2.39e-04	749	69	10	GO:0005509
GeneOntologyMolecularFunction	immune receptor activity	IL12RB2 CR1 CR1L CR2 CNTFR	2.66e-04	165	69	5	GO:0140375
GeneOntologyMolecularFunction	opsonin receptor activity	CR1 CR1L	3.25e-04	8	69	2	GO:0001847
GeneOntologyMolecularFunction	cytidine deaminase activity	APOBEC3B APOBEC3F	8.96e-04	13	69	2	GO:0004126
GeneOntologyMolecularFunction	metalloendopeptidase inhibitor activity	TIMP4 WFIKKN2	1.37e-03	16	69	2	GO:0008191
GeneOntologyMolecularFunction	cytokine binding	IL12RB2 TRAF2 WFIKKN2 CNTFR	2.14e-03	157	69	4	GO:0019955
GeneOntologyBiologicalProcess	negative regulation of complement activation, classical pathway	CR1 CR1L CR2 SVEP1	7.95e-09	8	69	4	GO:0045959
GeneOntologyBiologicalProcess	regulation of complement activation, classical pathway	CR1 CR1L CR2 SVEP1	2.37e-08	10	69	4	GO:0030450
GeneOntologyBiologicalProcess	negative regulation of humoral immune response mediated by circulating immunoglobulin	CR1 CR1L CR2 SVEP1	5.56e-08	12	69	4	GO:0002924
GeneOntologyBiologicalProcess	negative regulation of complement activation	CR1 CR1L CR2 SVEP1	1.12e-07	14	69	4	GO:0045916
GeneOntologyBiologicalProcess	complement activation	CFHR1 CFHR2 CR1 CR1L CR2 SVEP1	1.24e-07	70	69	6	GO:0006956
GeneOntologyBiologicalProcess	negative regulation of B cell mediated immunity	CR1 CR1L CR2 SVEP1	2.02e-07	16	69	4	GO:0002713
GeneOntologyBiologicalProcess	negative regulation of immunoglobulin mediated immune response	CR1 CR1L CR2 SVEP1	2.02e-07	16	69	4	GO:0002890
GeneOntologyBiologicalProcess	negative regulation of humoral immune response	CR1 CR1L CR2 SVEP1	4.28e-07	19	69	4	GO:0002921
GeneOntologyBiologicalProcess	regulation of humoral immune response mediated by circulating immunoglobulin	CR1 CR1L CR2 SVEP1	8.02e-07	22	69	4	GO:0002923
GeneOntologyBiologicalProcess	regulation of complement activation	CR1 CR1L CR2 SVEP1	1.90e-06	27	69	4	GO:0030449
GeneOntologyBiologicalProcess	negative regulation of lymphocyte mediated immunity	CLEC2D CR1 CR1L CR2 SVEP1	8.58e-06	83	69	5	GO:0002707
GeneOntologyBiologicalProcess	positive regulation of platelet activation	SELP SVEP1 GP9	1.27e-05	14	69	3	GO:0010572
GeneOntologyBiologicalProcess	complement activation, classical pathway	CR1 CR1L CR2 SVEP1	1.41e-05	44	69	4	GO:0006958
GeneOntologyBiologicalProcess	negative regulation of leukocyte mediated immunity	CLEC2D CR1 CR1L CR2 SVEP1	1.75e-05	96	69	5	GO:0002704
GeneOntologyBiologicalProcess	negative regulation of immune effector process	SLAMF8 CLEC2D CR1 CR1L CR2 SVEP1	1.96e-05	166	69	6	GO:0002698
GeneOntologyBiologicalProcess	immune effector process	SLAMF8 CFHR1 CFHR2 TRAF2 CLEC2D MUC19 CR1 CR1L CR2 ACE SVEP1 MYB	2.49e-05	859	69	12	GO:0002252
GeneOntologyBiologicalProcess	hemopoiesis	SLAMF8 FAM20C FBN1 CLEC2D MUC19 TMEM131L CR1 CR2 FST ACE APOBEC3B MYB APOBEC3F GP9	4.42e-05	1223	69	14	GO:0030097
GeneOntologyBiologicalProcess	regulation of humoral immune response	CR1 CR1L CR2 SVEP1	4.86e-05	60	69	4	GO:0002920
GeneOntologyBiologicalProcess	defense response to other organism	TRIM43B SLAMF8 SELP CFHR1 CFHR2 TRAF2 CLEC2D MUC19 TRIM43 CST11 CR1 CR1L CR2 APOBEC3B APOBEC3F	5.11e-05	1407	69	15	GO:0098542
GeneOntologyBiologicalProcess	hematopoietic progenitor cell differentiation	MUC19 FST ACE APOBEC3B MYB APOBEC3F	5.11e-05	197	69	6	GO:0002244
GeneOntologyBiologicalProcess	humoral immune response mediated by circulating immunoglobulin	CR1 CR1L CR2 SVEP1	5.53e-05	62	69	4	GO:0002455
GeneOntologyBiologicalProcess	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	CR1 CR1L CR2 SVEP1	7.07e-05	66	69	4	GO:0002823
GeneOntologyBiologicalProcess	ribonucleoside catabolic process	XDH APOBEC3B APOBEC3F	8.82e-05	26	69	3	GO:0042454
GeneOntologyBiologicalProcess	negative regulation of adaptive immune response	CR1 CR1L CR2 SVEP1	9.41e-05	71	69	4	GO:0002820
GeneOntologyBiologicalProcess	regulation of lymphocyte mediated immunity	TRAF2 CLEC2D CR1 CR1L CR2 SVEP1	1.26e-04	232	69	6	GO:0002706
GeneOntologyBiologicalProcess	regulation of B cell mediated immunity	CR1 CR1L CR2 SVEP1	1.43e-04	79	69	4	GO:0002712
GeneOntologyBiologicalProcess	regulation of immunoglobulin mediated immune response	CR1 CR1L CR2 SVEP1	1.43e-04	79	69	4	GO:0002889
GeneOntologyBiologicalProcess	negative regulation of immune response	SLAMF8 CLEC2D CR1 CR1L CR2 SVEP1	1.48e-04	239	69	6	GO:0050777
GeneOntologyBiologicalProcess	clearance of foreign intracellular DNA	APOBEC3B APOBEC3F	1.64e-04	6	69	2	GO:0044355
GeneOntologyBiologicalProcess	clearance of foreign intracellular nucleic acids	APOBEC3B APOBEC3F	1.64e-04	6	69	2	GO:0099046
GeneOntologyBiologicalProcess	nucleoside catabolic process	XDH APOBEC3B APOBEC3F	1.66e-04	32	69	3	GO:0009164
GeneOntologyBiologicalProcess	nucleobase-containing small molecule catabolic process	XDH APOBEC3B APOBEC3F	2.57e-04	37	69	3	GO:0034656
GeneOntologyBiologicalProcess	defense response to symbiont	TRIM43B SLAMF8 CFHR1 CFHR2 TRAF2 CLEC2D MUC19 TRIM43 CR1 CR1L CR2 APOBEC3B APOBEC3F	2.96e-04	1286	69	13	GO:0140546
GeneOntologyBiologicalProcess	glycosyl compound catabolic process	XDH APOBEC3B APOBEC3F	3.49e-04	41	69	3	GO:1901658
GeneOntologyBiologicalProcess	DNA cytosine deamination	APOBEC3B APOBEC3F	4.88e-04	10	69	2	GO:0070383
GeneOntologyBiologicalProcess	cytolysis by host of symbiont cells	CFHR1 CFHR2	4.88e-04	10	69	2	GO:0051838
GeneOntologyBiologicalProcess	myeloid cell development	FAM20C FBN1 MYB GP9	4.90e-04	109	69	4	GO:0061515
GeneOntologyBiologicalProcess	mature B cell differentiation	SLAMF8 MUC19 CR1	5.23e-04	47	69	3	GO:0002335
GeneOntologyBiologicalProcess	ribonucleoside metabolic process	XDH APOBEC3B APOBEC3F	5.56e-04	48	69	3	GO:0009119
GeneOntologyBiologicalProcess	cell killing	CFHR1 CFHR2 CLEC2D CST11 CR1 CR1L	5.65e-04	307	69	6	GO:0001906
GeneOntologyBiologicalProcess	B cell differentiation	SLAMF8 MUC19 CR1 CR2 MYB	5.67e-04	201	69	5	GO:0030183
GeneOntologyBiologicalProcess	regulation of leukocyte mediated immunity	TRAF2 CLEC2D CR1 CR1L CR2 SVEP1	5.85e-04	309	69	6	GO:0002703
GeneOntologyBiologicalProcess	cytidine to uridine editing	APOBEC3B APOBEC3F	7.12e-04	12	69	2	GO:0016554
GeneOntologyBiologicalProcess	humoral immune response	CFHR1 CFHR2 CR1 CR1L CR2 SVEP1	7.13e-04	321	69	6	GO:0006959
GeneOntologyBiologicalProcess	regulation of complement-dependent cytotoxicity	CR1 CR1L	8.40e-04	13	69	2	GO:1903659
GeneOntologyBiologicalProcess	innate immune response	TRIM43B SLAMF8 TRAF2 CLEC2D MUC19 TRIM43 CR1 CR1L CR2 APOBEC3B APOBEC3F	9.42e-04	1092	69	11	GO:0045087
GeneOntologyBiologicalProcess	cytidine catabolic process	APOBEC3B APOBEC3F	9.78e-04	14	69	2	GO:0006216
GeneOntologyBiologicalProcess	DNA deamination	APOBEC3B APOBEC3F	9.78e-04	14	69	2	GO:0045006
GeneOntologyBiologicalProcess	cytidine metabolic process	APOBEC3B APOBEC3F	9.78e-04	14	69	2	GO:0046087
GeneOntologyBiologicalProcess	cytidine deamination	APOBEC3B APOBEC3F	9.78e-04	14	69	2	GO:0009972
GeneOntologyBiologicalProcess	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	TRAF2 CR1 CR1L CR2 SVEP1	1.14e-03	235	69	5	GO:0002822
GeneOntologyBiologicalProcess	negative regulation of immune system process	SLAMF8 FBN1 CLEC2D TMEM131L CR1 CR1L CR2 SVEP1	1.19e-03	631	69	8	GO:0002683
GeneOntologyBiologicalProcess	leukocyte differentiation	SLAMF8 FAM20C FBN1 CLEC2D MUC19 TMEM131L CR1 CR2 MYB	1.22e-03	789	69	9	GO:0002521
GeneOntologyBiologicalProcess	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3B APOBEC3F	1.28e-03	16	69	2	GO:0045869
GeneOntologyBiologicalProcess	complement receptor mediated signaling pathway	CR1 CR2	1.28e-03	16	69	2	GO:0002430
GeneOntologyBiologicalProcess	complement-dependent cytotoxicity	CR1 CR1L	1.28e-03	16	69	2	GO:0097278
GeneOntologyBiologicalProcess	pyrimidine ribonucleoside metabolic process	APOBEC3B APOBEC3F	1.28e-03	16	69	2	GO:0046131
GeneOntologyBiologicalProcess	pyrimidine ribonucleoside catabolic process	APOBEC3B APOBEC3F	1.28e-03	16	69	2	GO:0046133
GeneOntologyBiologicalProcess	regulation of immune effector process	SLAMF8 TRAF2 CLEC2D CR1 CR1L CR2 SVEP1	1.34e-03	497	69	7	GO:0002697
GeneOntologyBiologicalProcess	regulation of platelet activation	SELP SVEP1 GP9	1.41e-03	66	69	3	GO:0010543
GeneOntologyBiologicalProcess	blood coagulation, fibrin clot formation	F13B GP9	1.45e-03	17	69	2	GO:0072378
GeneOntologyBiologicalProcess	female pregnancy	GJB2 CSMD1 CR1 CR1L ACE	1.48e-03	249	69	5	GO:0007565
GeneOntologyBiologicalProcess	nucleoside metabolic process	XDH APOBEC3B APOBEC3F	1.54e-03	68	69	3	GO:0009116
GeneOntologyBiologicalProcess	regulation of adaptive immune response	TRAF2 CR1 CR1L CR2 SVEP1	1.56e-03	252	69	5	GO:0002819
GeneOntologyBiologicalProcess	pyrimidine nucleoside catabolic process	APOBEC3B APOBEC3F	1.63e-03	18	69	2	GO:0046135
GeneOntologyBiologicalProcess	negative regulation of leukocyte differentiation	FBN1 CLEC2D TMEM131L CR1	1.65e-03	151	69	4	GO:1902106
GeneOntologyBiologicalProcess	regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3B APOBEC3F	1.82e-03	19	69	2	GO:0045091
GeneOntologyBiologicalProcess	base conversion or substitution editing	APOBEC3B APOBEC3F	1.82e-03	19	69	2	GO:0016553
GeneOntologyBiologicalProcess	gap junction assembly	GJB2 ACE	1.82e-03	19	69	2	GO:0016264
GeneOntologyBiologicalProcess	complement activation, alternative pathway	CR1 CR2	1.82e-03	19	69	2	GO:0006957
GeneOntologyBiologicalProcess	regulation of interleukin-2 production	TRAF2 CLEC2D CR1	1.96e-03	74	69	3	GO:0032663
GeneOntologyBiologicalProcess	negative regulation of hemopoiesis	FBN1 CLEC2D TMEM131L CR1	1.99e-03	159	69	4	GO:1903707
GeneOntologyBiologicalProcess	single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3B APOBEC3F	2.02e-03	20	69	2	GO:0039692
MousePheno	tight skin	FBN1 IRF6 FST	2.78e-05	14	61	3	MP:0001198
Domain	Sushi	SELP CFHR1 CFHR2 CSMD1 CR1 CR1L CR2 SVEP1 F13B	2.42e-13	52	69	9	PF00084
Domain	CCP	SELP CFHR1 CFHR2 CSMD1 CR1 CR1L CR2 SVEP1 F13B	3.48e-13	54	69	9	SM00032
Domain	SUSHI	SELP CFHR1 CFHR2 CSMD1 CR1 CR1L CR2 SVEP1 F13B	4.93e-13	56	69	9	PS50923
Domain	Sushi_SCR_CCP_dom	SELP CFHR1 CFHR2 CSMD1 CR1 CR1L CR2 SVEP1 F13B	5.83e-13	57	69	9	IPR000436
Domain	EGF_3	SELP FAT1 FBN1 OIT3 EGF PGAP6 SVEP1	2.54e-05	235	69	7	PS50026
Domain	EGF	SELP FAT1 FBN1 OIT3 EGF PGAP6 SVEP1	2.54e-05	235	69	7	SM00181
Domain	EGF_Ca-bd_CS	FAT1 FBN1 OIT3 EGF SVEP1	2.94e-05	97	69	5	IPR018097
Domain	EGF_CA	FAT1 FBN1 OIT3 EGF SVEP1	3.25e-05	99	69	5	PS01187
Domain	ASX_HYDROXYL	FAT1 FBN1 OIT3 EGF SVEP1	3.41e-05	100	69	5	PS00010
Domain	EGF-like_dom	SELP FAT1 FBN1 OIT3 EGF PGAP6 SVEP1	3.67e-05	249	69	7	IPR000742
Domain	EGF_1	SELP FAT1 FBN1 OIT3 EGF PGAP6 SVEP1	4.27e-05	255	69	7	PS00022
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT1 FBN1 OIT3 EGF SVEP1	4.51e-05	106	69	5	IPR000152
Domain	EGF_2	SELP FAT1 FBN1 OIT3 EGF PGAP6 SVEP1	5.45e-05	265	69	7	PS01186
Domain	EGF_CA	FAT1 FBN1 OIT3 EGF SVEP1	8.81e-05	122	69	5	SM00179
Domain	EGF-like_Ca-bd_dom	FAT1 FBN1 OIT3 EGF SVEP1	9.52e-05	124	69	5	IPR001881
Domain	C_TYPE_LECTIN_1	SELP MRC2 CLEC2D KLRG2	2.18e-04	80	69	4	PS00615
Domain	Lectin_C	SELP MRC2 CLEC2D KLRG2	2.63e-04	84	69	4	PF00059
Domain	CLECT	SELP MRC2 CLEC2D KLRG2	2.63e-04	84	69	4	SM00034
Domain	C_TYPE_LECTIN_2	SELP MRC2 CLEC2D KLRG2	2.76e-04	85	69	4	PS50041
Domain	Growth_fac_rcpt_	FAT1 FBN1 IGFBP1 EGF SVEP1	2.79e-04	156	69	5	IPR009030
Domain	C-type_lectin-like	SELP MRC2 CLEC2D KLRG2	2.88e-04	86	69	4	IPR001304
Domain	EGF_CA	FAT1 FBN1 EGF SVEP1	2.88e-04	86	69	4	PF07645
Domain	Kazal_2	SLCO1A2 WFIKKN2 FST	3.16e-04	36	69	3	PF07648
Domain	EGF-like_CS	SELP FAT1 FBN1 EGF PGAP6 SVEP1	4.04e-04	261	69	6	IPR013032
Domain	-	SELP MRC2 CLEC2D KLRG2	4.56e-04	97	69	4	3.10.100.10
Domain	TB	FBN1 FST	4.76e-04	9	69	2	PS51364
Domain	TB_dom	FBN1 FST	4.76e-04	9	69	2	IPR017878
Domain	C-type_lectin-like/link	SELP MRC2 CLEC2D KLRG2	4.93e-04	99	69	4	IPR016186
Domain	KAZAL	SLCO1A2 WFIKKN2 FST	6.54e-04	46	69	3	SM00280
Domain	CTDL_fold	SELP MRC2 CLEC2D KLRG2	6.61e-04	107	69	4	IPR016187
Domain	Pentaxin-related	ADGRD2 SVEP1	7.24e-04	11	69	2	IPR001759
Domain	-	EGF SVEP1	7.24e-04	11	69	2	2.40.155.10
Domain	GFP-like	EGF SVEP1	7.24e-04	11	69	2	IPR023413
Domain	Pentaxin	ADGRD2 SVEP1	7.24e-04	11	69	2	PF00354
Domain	KAZAL_2	SLCO1A2 WFIKKN2 FST	8.35e-04	50	69	3	PS51465
Domain	APOBEC_N	APOBEC3B APOBEC3F	8.67e-04	12	69	2	PF08210
Domain	TIL	MUC19 MUC5AC	8.67e-04	12	69	2	PF01826
Domain	APOBEC_N	APOBEC3B APOBEC3F	8.67e-04	12	69	2	IPR013158
Domain	C8	MUC19 MUC5AC	8.67e-04	12	69	2	PF08742
Domain	Kazal_dom	SLCO1A2 WFIKKN2 FST	8.85e-04	51	69	3	IPR002350
Domain	Unchr_dom_Cys-rich	MUC19 MUC5AC	1.02e-03	13	69	2	IPR014853
Domain	C8	MUC19 MUC5AC	1.02e-03	13	69	2	SM00832
Domain	TIL_dom	MUC19 MUC5AC	1.19e-03	14	69	2	IPR002919
Domain	APOBEC/CMP_deaminase_Zn-bd	APOBEC3B APOBEC3F	1.19e-03	14	69	2	IPR016192
Domain	EGF	SELP FAT1 EGF SVEP1	1.22e-03	126	69	4	PF00008
Domain	ConA-like_dom	TRIM43B FAT1 TRIM43 ADGRD2 SVEP1	1.29e-03	219	69	5	IPR013320
Domain	CYT_DCMP_DEAMINASES_2	APOBEC3B APOBEC3F	1.37e-03	15	69	2	PS51747
Domain	VWD	MUC19 MUC5AC	1.56e-03	16	69	2	SM00216
Domain	VWF_type-D	MUC19 MUC5AC	1.56e-03	16	69	2	IPR001846
Domain	VWFD	MUC19 MUC5AC	1.56e-03	16	69	2	PS51233
Domain	VWD	MUC19 MUC5AC	1.56e-03	16	69	2	PF00094
Domain	TSP_1	SEMA5B ADAMTS17 THSD7B	1.64e-03	63	69	3	PF00090
Domain	Cytidine_deaminase-like	APOBEC3B APOBEC3F	1.76e-03	17	69	2	IPR016193
Domain	CYT_DCMP_DEAMINASES_1	APOBEC3B APOBEC3F	1.76e-03	17	69	2	PS00903
Domain	CMP_dCMP_Zn-bd	APOBEC3B APOBEC3F	1.76e-03	17	69	2	IPR002125
Domain	TSP1	SEMA5B ADAMTS17 THSD7B	1.79e-03	65	69	3	SM00209
Domain	TSP1_rpt	SEMA5B ADAMTS17 THSD7B	1.79e-03	65	69	3	IPR000884
Domain	TSP1	SEMA5B ADAMTS17 THSD7B	1.79e-03	65	69	3	PS50092
Domain	CTCK_1	MUC19 MUC5AC	1.98e-03	18	69	2	PS01185
Domain	KAZAL_1	WFIKKN2 FST	1.98e-03	18	69	2	PS00282
Domain	VWC_out	MUC19 MUC5AC	2.21e-03	19	69	2	SM00215
Domain	CT	MUC19 MUC5AC	2.96e-03	22	69	2	SM00041
Domain	NTR	TIMP4 WFIKKN2	3.24e-03	23	69	2	PS50189
Domain	Netrin_domain	TIMP4 WFIKKN2	3.24e-03	23	69	2	IPR001134
Domain	Cys_knot_C	MUC19 MUC5AC	3.82e-03	25	69	2	IPR006207
Domain	CTCK_2	MUC19 MUC5AC	3.82e-03	25	69	2	PS01225
Domain	TIMP-like_OB-fold	TIMP4 WFIKKN2	4.13e-03	26	69	2	IPR008993
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	SEMA5B ADAMTS17 MUC19 THSD7B MUC5AC	4.46e-05	109	51	5	MM15164
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	SEMA5B ADAMTS17 THSD7B MUC5AC	1.04e-04	68	51	4	M27303
Pathway	WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS	FAT1 IRF6 CR1 CR1L	1.38e-04	73	51	4	MM15906
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR	CFHR1 CFHR2	1.91e-04	6	51	2	M47880
Pathway	WP_16P112_DISTAL_DELETION_SYNDROME	TRAF2 CR2 SH2B1	2.25e-04	33	51	3	M40056
Pathway	REACTOME_MRNA_EDITING_C_TO_U_CONVERSION	APOBEC3B APOBEC3F	2.66e-04	7	51	2	MM15412
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	SEMA5B ADAMTS17 THSD7B	3.72e-04	39	51	3	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	SEMA5B ADAMTS17 THSD7B	3.72e-04	39	51	3	MM15165
Pathway	WP_COMPLEMENT_SYSTEM	SELP CFHR2 CR1 CR2	3.95e-04	96	51	4	M39581
Pathway	REACTOME_MRNA_EDITING	APOBEC3B APOBEC3F	4.55e-04	9	51	2	MM15445
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	SEMA5B ADAMTS17 THSD7B MUC5AC	6.84e-04	111	51	4	M27416
Pathway	REACTOME_COMPLEMENT_CASCADE	CFHR1 CFHR2 CR1 CR2	7.82e-04	115	51	4	M19752
Pubmed	Complement-dependent P-selectin expression and injury following ischemic stroke.	SELP CR1 CR1L CR2	7.08e-11	5	69	4	17082645
Pubmed	Mapping of recombinant retrovirus integration sites that cause expression of the viral genome in murine embryonal carcinoma cells.	CR1 CR1L CR2 MYB	4.63e-09	11	69	4	1543915
Pubmed	Murine complement receptor gene family. II. Identification and characterization of the murine homolog (Cr2) to human CR2 and its molecular linkage to Crry.	CR1 CR1L CR2	7.47e-09	3	69	3	2528587
Pubmed	Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein.	CR1 CR1L CR2	7.47e-09	3	69	3	7528766
Pubmed	The murine complement receptor gene family. IV. Alternative splicing of Cr2 gene transcripts predicts two distinct gene products that share homologous domains with both human CR2 and CR1.	CR1 CR1L CR2	7.47e-09	3	69	3	2139460
Pubmed	New genetic associations detected in a host response study to hepatitis B vaccine.	SLAMF8 CFHR1 CFHR2 FNDC3B IL12RB2 TRAF2 UBE2O SLITRK3 CR1 CR2 ACE F13B CNTFR	7.68e-09	824	69	13	20237496
Pubmed	Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c.	IRF6 CR1 CR1L CR2	1.00e-08	13	69	4	16002709
Pubmed	Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection.	CR1 CR1L CR2	2.99e-08	4	69	3	16127466
Pubmed	Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma.	CR1 CR1L CR2	2.99e-08	4	69	3	30217731
Pubmed	Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.	CR1 CR1L CR2	7.45e-08	5	69	3	20962256
Pubmed	Genetic organization of complement receptor-related genes in the mouse.	CR1 CR1L CR2	4.16e-07	8	69	3	2564419
Pubmed	Mouse kalinin B1 (laminin beta 3 chain): cloning and tissue distribution.	SELP CR1 CR1L	4.16e-07	8	69	3	7898049
Pubmed	Functional identification of transcription control sequences of the mouse Crry gene.	CR1 CR1L	3.88e-06	2	69	2	8335915
Pubmed	Deficiency of Mouse FHR-1 Homolog, FHR-E, Accelerates Sepsis, and Acute Kidney Injury Through Enhancing the LPS-Induced Alternative Complement Pathway.	CFHR1 CFHR2	3.88e-06	2	69	2	32636836
Pubmed	Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes.	CR1 CR2	3.88e-06	2	69	2	14635039
Pubmed	Crry/p65, a membrane complement regulatory protein, has costimulatory properties on mouse T cells.	CR1 CR1L	3.88e-06	2	69	2	10779754
Pubmed	Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion.	CR1 CR1L	3.88e-06	2	69	2	16444293
Pubmed	Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1.	CR1 CR1L	3.88e-06	2	69	2	1730912
Pubmed	cDNA cloning and expression of human activin betaE subunit.	INHBE FST	3.88e-06	2	69	2	12242034
Pubmed	Mesangial cell complement receptor 1-related protein y limits complement-dependent neutrophil accumulation in immune complex glomerulonephritis.	CR1 CR1L	3.88e-06	2	69	2	19740350
Pubmed	Epidermal Growth Factor Removal or Tyrphostin AG1478 Treatment Reduces Goblet Cells & Mucus Secretion of Epithelial Cells from Asthmatic Children Using the Air-Liquid Interface Model.	EGF MUC5AC	3.88e-06	2	69	2	26057128
Pubmed	The role of complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) in promoting C3 fragment deposition and membrane attack complex formation on normal peripheral human B cells.	CR1 CR2	3.88e-06	2	69	2	11981823
Pubmed	A novel ADAMTS17 variant that causes Weill-Marchesani syndrome 4 alters fibrillin-1 and collagen type I deposition in the extracellular matrix.	FBN1 ADAMTS17	3.88e-06	2	69	2	31726086
Pubmed	Expansion of the complement receptor gene family. Identification in the mouse of two new genes related to the CR1 and CR2 gene family.	CR1 CR1L	3.88e-06	2	69	2	2952719
Pubmed	Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex.	CR1 CR2	3.88e-06	2	69	2	1708808
Pubmed	The extended multidomain solution structures of the complement protein Crry and its chimeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy.	CR1 CR1L	3.88e-06	2	69	2	12767833
Pubmed	Regulation of complement activity via the alternative pathway in placentas of mouse spontaneous abortions.	CR1 CR1L	3.88e-06	2	69	2	20484840
Pubmed	Astrocyte-specific expression of a soluble form of the murine complement control protein Crry confers demyelination protection in the cuprizone model.	CR1 CR1L	3.88e-06	2	69	2	17674370
Pubmed	Molecular cloning of a human serum protein structurally related to complement factor H.	CFHR1 CFHR2	3.88e-06	2	69	2	1711047
Pubmed	Complement inhibitor, complement receptor 1-related gene/protein y-Ig attenuates intestinal damage after the onset of mesenteric ischemia/reperfusion injury in mice.	CR1 CR1L	3.88e-06	2	69	2	11698469
Pubmed	Expression of a Crry/p65 is reduced in acute lung injury induced by extracellular histones.	CR1 CR1L	3.88e-06	2	69	2	34709768
Pubmed	The murine complement regulator Crry: new insights into the immunobiology of complement regulation.	CR1 CR1L	3.88e-06	2	69	2	11915940
Pubmed	Mouse Crry/p65. Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF.	CR1 CR1L	3.88e-06	2	69	2	7691944
Pubmed	Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases.	CFHR1 CFHR2	3.88e-06	2	69	2	33651882
Pubmed	Comparative functional evolution of human and mouse CR1 and CR2.	CR1 CR2	3.88e-06	2	69	2	18713965
Pubmed	The murine complement receptor gene family. Analysis of mCRY gene products and their homology to human CR1.	CR1 CR1L	3.88e-06	2	69	2	2911011
Pubmed	Prevention of collagen-induced arthritis in mice transgenic for the complement inhibitor complement receptor 1-related gene/protein y.	CR1 CR1L	3.88e-06	2	69	2	12902517
Pubmed	Cutting edge: treatment of complement regulatory protein deficiency by retroviral in vivo gene therapy.	CR1 CR1L	3.88e-06	2	69	2	17015675
Pubmed	Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH.	CR1 CR1L	3.88e-06	2	69	2	23153828
Pubmed	Complement receptor type 1 and 2 (CR1 and CR2) gene polymorphisms and plasma protein levels are associated with the Dengue disease severity.	CR1 CR2	3.88e-06	2	69	2	37833411
Pubmed	[THE COMBINATION OF EXPRESSION OF MARKERS CR1 AND CR2 (CD35/CD21) IN DIAGNOSTIC OF B-CELL LYMPHOPROLIFERATIVE DISEASES].	CR1 CR2	3.88e-06	2	69	2	26189291
Pubmed	Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic mice.	CR1 CR1L	3.88e-06	2	69	2	12973023
Pubmed	Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization.	CR1 CR2	3.88e-06	2	69	2	23440418
Pubmed	Central nervous system-targeted expression of the complement inhibitor sCrry prevents experimental allergic encephalomyelitis.	CR1 CR1L	3.88e-06	2	69	2	10586048
Pubmed	In vivo correction of complement regulatory protein deficiency with an inhibitor targeting the red blood cell membrane.	CR1 CR1L	3.88e-06	2	69	2	16301687
Pubmed	Expression dynamics of Crry at the implantation sites in normal pregnancy and response against miscarriage induction.	CR1 CR1L	3.88e-06	2	69	2	36450590
Pubmed	Complement regulatory protein Crry/p65-mediated signaling in T lymphocytes: role of its cytoplasmic domain and partitioning into lipid rafts.	CR1 CR1L	3.88e-06	2	69	2	16301324
Pubmed	The murine complement receptor gene family. III. The genomic and transcriptional complexity of the Crry and Crry-ps genes.	CR1 CR1L	3.88e-06	2	69	2	2307848
Pubmed	Complement regulatory protein Crry/p65 costimulation expands natural treg cells with enhanced suppressive properties in proteoglycan-induced arthritis.	CR1 CR1L	3.88e-06	2	69	2	21380996
Pubmed	Asprosin-neutralizing antibodies as a treatment for metabolic syndrome.	FBN1 APOBEC3B APOBEC3F	4.11e-06	16	69	3	33904407
Pubmed	An interactive association of common sequence variants in the neuropeptide Y gene with susceptibility to ischemic stroke.	SELP ACE F13B	5.97e-06	18	69	3	17702963
Pubmed	Constitutive expression of TNF-alpha and -beta genes in mouse embryo: roles of cytokines as regulator and effector on development.	CR1 CR1L CR2	9.69e-06	21	69	3	8138038
Pubmed	APOBEC3 deletion increases the risk of breast cancer: a meta-analysis.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	27602762
Pubmed	A novel role for APOBEC3: susceptibility to sexual transmission of murine acquired immunodeficiency virus (mAIDS) is aggravated in APOBEC3 deficient mice.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	22691411
Pubmed	Studies on the restriction of murine leukemia viruses by mouse APOBEC3.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	22666481
Pubmed	Duplication and divergence of the amino-terminal coding region of the complement receptor 1 (CR1) gene. An example of concerted (horizontal) evolution within a gene.	CR1 CR1L	1.16e-05	3	69	2	2295627
Pubmed	APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	16648136
Pubmed	Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	23533681
Pubmed	IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	23315078
Pubmed	Requirement for Fc effector mechanisms in the APOBEC3/Rfv3-dependent neutralizing antibody response.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	25589647
Pubmed	Requirement for CD4(+) T cells in the Friend murine retrovirus neutralizing antibody response: evidence for functional T cells in genetic low-recovery mice.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	9765497
Pubmed	Serum FHR1 binding to necrotic-type cells activates monocytic inflammasome and marks necrotic sites in vasculopathies.	CFHR1 CFHR2	1.16e-05	3	69	2	31273197
Pubmed	APOBEC3 inhibition of mouse mammary tumor virus infection: the role of cytidine deamination versus inhibition of reverse transcription.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	23449789
Pubmed	Transgenic expression of a soluble complement inhibitor protects against renal disease and promotes survival in MRL/lpr mice.	CR1 CR1L	1.16e-05	3	69	2	11907125
Pubmed	Anti-Friend virus antibody is associated with recovery from viremia and loss of viral leukemia cell-surface antigens in leukemic mice. Identification of Rfv-3 as a gene locus influencing antibody production.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	286744
Pubmed	An allelic variant of Crry in the murine Sle1c lupus susceptibility interval is not impaired in its ability to regulate complement activation.	CR1 CR1L	1.16e-05	3	69	2	20660348
Pubmed	Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	24725948
Pubmed	Identification of a non-H-2 gene (Rfv-3) influencing recovery from viremia and leukemia induced by Friend virus complex.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	284359
Pubmed	Impact of Suboptimal APOBEC3G Neutralization on the Emergence of HIV Drug Resistance in Humanized Mice.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	31801862
Pubmed	Deamination hotspots among APOBEC3 family members are defined by both target site sequence context and ssDNA secondary structure.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	31943071
Pubmed	[Hepatitis B virus X protein upregulates the expression of CD59 and Crry in mouse podocytes].	CR1 CR1L	1.16e-05	3	69	2	21215189
Pubmed	Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	20566830
Pubmed	Chromosome mapping of Rfv3, a host resistance gene to Friend murine retrovirus.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	7884913
Pubmed	N-linked glycosylation protects gammaretroviruses against deamination by APOBEC3 proteins.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	25505062
Pubmed	Molecular analysis of γ1, γ3, and α class switch recombination junctions in APOBEC3-deficient mice using high-throughput sequencing.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	31595054
Pubmed	A critical role for murine complement regulator crry in fetomaternal tolerance.	CR1 CR1L	1.16e-05	3	69	2	10642554
Pubmed	Role of APOBEC3 in genetic diversity among endogenous murine leukemia viruses.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	17967065
Pubmed	Inhibition of xenotropic murine leukemia virus-related virus by APOBEC3 proteins and antiviral drugs.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	20335265
Pubmed	Deaminase-Dead Mouse APOBEC3 Is an In Vivo Retroviral Restriction Factor.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	29593034
Pubmed	Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	21998583
Pubmed	Effects of zidovudine on Friend virus complex infection in Rfv-3r/s genotype-containing mice used as a model for HIV infection.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	2157836
Pubmed	Initial sequencing and comparative analysis of the mouse genome.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	12466850
Pubmed	Murine Leukemia Virus P50 Protein Counteracts APOBEC3 by Blocking Its Packaging.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	32641479
Pubmed	Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes.	CR1 CR2	1.16e-05	3	69	2	7690834
Pubmed	APOBEC3 deletion polymorphism is associated with epithelial ovarian cancer risk among Chinese women.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	24577894
Pubmed	Spontaneous recovery from Friend retrovirus-induced leukemia. Mapping of the Rfv-2 gene in the Q/TL region of mouse MHC.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	1541833
Pubmed	In Vivo Examination of Mouse APOBEC3- and Human APOBEC3A- and APOBEC3G-Mediated Restriction of Parvovirus and Herpesvirus Infection in Mouse Models.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	27356895
Pubmed	A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.	CR1 CR2	1.16e-05	3	69	2	3782802
Pubmed	Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	23671100
Pubmed	Structural perspectives on HIV-1 Vif and APOBEC3 restriction factor interactions.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	31518043
Pubmed	APOBEC3 signature mutations in chronic lymphocytic leukemia.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	24840555
Pubmed	Biochemical and biological studies of mouse APOBEC3.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	24453360
Pubmed	Tissue-specific deletion of Crry from mouse proximal tubular epithelial cells increases susceptibility to renal ischemia-reperfusion injury.	CR1 CR1L	1.16e-05	3	69	2	24850152
Pubmed	APOBEC3-independent interferon-induced viral clearance in hepatitis B virus transgenic mice.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	18434399
Pubmed	Induction of APOBEC3 in vivo causes increased restriction of retrovirus infection.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	19153238
Pubmed	Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	18772436
Pubmed	Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	18786991
Pubmed	circFAT1(e2) Inhibits Cell Apoptosis and Facilitates Progression in Vascular Smooth Muscle Cells through miR-298/MYB Axis.	FAT1 MYB	1.16e-05	3	69	2	34938350
Pubmed	The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	20702647
Pubmed	Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor.	APOBEC3B APOBEC3F	1.16e-05	3	69	2	20980520
Interaction	CR1 interactions	CR1 CR1L CR2	2.03e-06	8	68	3	int:CR1
Cytoband	1q32	CFHR1 CR1 CR2	5.70e-05	49	69	3	1q32
Cytoband	Ensembl 112 genes in cytogenetic band chr1q31	CFHR1 CFHR2 F13B	2.03e-04	75	69	3	chr1q31
Cytoband	2q11.1	TRIM43B TRIM43	8.21e-04	28	69	2	2q11.1
Cytoband	Ensembl 112 genes in cytogenetic band chr1q32	IRF6 CR1 CR1L CR2	9.76e-04	290	69	4	chr1q32
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELP CFHR1 CFHR2 CSMD1 CR1 CR1L CR2 SVEP1 F13B	2.42e-14	57	48	9	1179
GeneFamily	Complement system\|Sushi domain containing	CFHR1 CFHR2 CR1 CR1L CR2	3.77e-08	36	48	5	492
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	SLAMF8 SELP MRC2 CR1 CR2 ACE GP9	7.54e-05	394	48	7	471
GeneFamily	C-type lectin domain family	MRC2 CLEC2D KLRG2	2.62e-04	47	48	3	494
GeneFamily	Apolipoprotein B mRNA editing enzyme catalytic subunits	APOBEC3B APOBEC3F	4.48e-04	12	48	2	406
GeneFamily	CD molecules\|Mucins	MUC19 MUC5AC	1.40e-03	21	48	2	648
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	ZSCAN20 MYB	8.73e-03	53	48	2	532
GeneFamily	Fibronectin type III domain containing	FNDC3B IL12RB2 CNTFR	8.79e-03	160	48	3	555
Coexpression	NABA_MATRISOME	FAM20C INHBE FBN1 OIT3 IGFBP1 EGF SEMA5B TIMP4 WFIKKN2 CLEC2D ADAMTS17 MUC19 CST11 FST MUC5AC SVEP1 F13B	6.98e-10	1008	69	17	MM17056
Coexpression	NABA_MATRISOME	FAM20C INHBE FBN1 OIT3 IGFBP1 EGF SEMA5B TIMP4 WFIKKN2 CLEC2D ADAMTS17 MUC19 CST11 FST MUC5AC SVEP1 F13B	9.13e-10	1026	69	17	M5889
Coexpression	NABA_MATRISOME_ASSOCIATED	FAM20C INHBE EGF SEMA5B TIMP4 WFIKKN2 CLEC2D ADAMTS17 MUC19 CST11 FST MUC5AC F13B	5.70e-08	738	69	13	MM17058
Coexpression	NABA_MATRISOME_ASSOCIATED	FAM20C INHBE EGF SEMA5B TIMP4 WFIKKN2 CLEC2D ADAMTS17 MUC19 CST11 FST MUC5AC F13B	6.97e-08	751	69	13	M5885
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	FNDC3B POGLUT3 FAT1 FBN1 MRC2 XDH CSMD1 ACE SVEP1	9.24e-06	445	66	9	GSM777043_500
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FBN1 MRC2 ADAMTS17 XDH FST SVEP1	2.05e-07	163	69	6	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 CTTNBP2 LPCAT2 MRC2 SLCO1A2 KLRG2	5.04e-07	190	69	6	b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	FNDC3B FBN1 LPCAT2 MRC2 ADAMTS17 SVEP1	5.19e-07	191	69	6	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC3B POGLUT3 FBN1 MRC2 ACE SVEP1	5.35e-07	192	69	6	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POGLUT3 FBN1 MRC2 FST ACE SVEP1	5.35e-07	192	69	6	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNDC3B POGLUT3 FBN1 MRC2 ACE SVEP1	5.35e-07	192	69	6	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 CTTNBP2 MRC2 SLCO1A2 KLRG2 FST	5.52e-07	193	69	6	0f2167eef8203a5659c8c72e4e77646003d64797
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFHR1 FBN1 MRC2 FST SVEP1 CNTFR	5.69e-07	194	69	6	02b8102be9414d6964cd71019613edff6d88b893
ToppCell	15-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	FBN1 MRC2 WFIKKN2 THSD7B SVEP1 CNTFR	6.04e-07	196	69	6	7e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FNDC3B FBN1 MRC2 ADAMTS17 FST SVEP1	6.60e-07	199	69	6	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFHR1 CFHR2 GJB2 IGFBP1 F13B	2.51e-06	139	69	5	82bf5ba69a907fbd9b4e2b2dd1dd27b8c4c75f25
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFHR1 CFHR2 GJB2 IGFBP1 F13B	2.51e-06	139	69	5	fc9ac09c2106e88104a52575832d71d17765eec8
ToppCell	facs-Liver-Hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFHR1 CFHR2 GJB2 IGFBP1 F13B	2.51e-06	139	69	5	fc4b39ac9a10cf0acacfebbc4295edf324d930d5
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFHR1 CFHR2 GJB2 IGFBP1 F13B	2.51e-06	139	69	5	4ddfbc36a0560fb70594627178bff652ab1ea3e9
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRIM43B FAT1 CTTNBP2 SLCO1A2 KLRG2	6.34e-06	168	69	5	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	facs-Lung-24m-Mesenchymal-myofibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELP TBC1D32 FAT1 FST GP9	7.51e-06	174	69	5	a7ade7372e83edd4e3983e77f8417b51f0b47340
ToppCell	TCGA-Liver\|World / Sample_Type by Project: Shred V9	CFHR1 CFHR2 INHBE IGFBP1 F13B	7.51e-06	174	69	5	452932f08cf53e5949672a025d78cecb874aa4b0
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CTTNBP2 POLH IRF6 PPP6R2 SH2B1	7.51e-06	174	69	5	6c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-4\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	IL12RB2 FBN1 TIMP4 CR1 SVEP1	7.72e-06	175	69	5	16849ea8f0985108baa2085f34c3de14a4f9f28b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 CTTNBP2 MRC2 SLCO1A2 KLRG2	7.94e-06	176	69	5	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 MRC2 FST SVEP1 CNTFR	8.85e-06	180	69	5	c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 MRC2 FST SVEP1 CNTFR	8.85e-06	180	69	5	32c6a3886428d82fb4355d987c6d2645f333447b
ToppCell	18-Airway-Epithelial-Submucosal_gland_basal\|Airway / Age, Tissue, Lineage and Cell class	ADAMTS17 XDH IRF6 THSD7B MYB	9.10e-06	181	69	5	33938e6521712058312879f84f4ae381c2bfc379
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 LPCAT2 MRC2 SLCO1A2 KLRG2	9.10e-06	181	69	5	071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELP FBN1 IRF6 ACE CEMIP2	9.34e-06	182	69	5	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELP FBN1 IRF6 ACE CEMIP2	9.34e-06	182	69	5	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 CTTNBP2 MRC2 SLCO1A2 KLRG2	9.59e-06	183	69	5	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 CTTNBP2 SEMA5B SLCO1A2 KLRG2	1.01e-05	185	69	5	34fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 MRC2 ADAMTS17 FST SVEP1	1.01e-05	185	69	5	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 MRC2 ADAMTS17 FST SVEP1	1.01e-05	185	69	5	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 CTTNBP2 SEMA5B SLCO1A2 KLRG2	1.01e-05	185	69	5	8816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCell	(0)_MSCs\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	FBN1 TIMP4 CSMD1 FST SVEP1	1.04e-05	186	69	5	a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 MRC2 ADAMTS17 CSMD1 SVEP1	1.04e-05	186	69	5	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	FBN1 CLEC2D CSMD1 ACE SVEP1	1.04e-05	186	69	5	e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCell	(0)_MSCs-(00)_Lepr-MSC\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	FBN1 TIMP4 CSMD1 FST SVEP1	1.04e-05	186	69	5	f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CTTNBP2 MRC2 SLCO1A2 KLRG2 FST	1.06e-05	187	69	5	9225caf66e06ebe57e90d677122acb6498607f36
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 CTTNBP2 SEMA5B KLRG2 ODAD2	1.09e-05	188	69	5	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 CTTNBP2 SEMA5B KLRG2 ODAD2	1.09e-05	188	69	5	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBN1 MRC2 ADAMTS17 SVEP1 CNTFR	1.12e-05	189	69	5	e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP CTTNBP2 IRF6 ACE CEMIP2	1.12e-05	189	69	5	9da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FBN1 MRC2 ADAMTS17 XDH SVEP1	1.18e-05	191	69	5	3379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAT1 FBN1 THSD7B SVEP1 CNTFR	1.18e-05	191	69	5	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	FBN1 MRC2 ADAMTS17 XDH SVEP1	1.18e-05	191	69	5	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELP CTTNBP2 IRF6 ACE CEMIP2	1.18e-05	191	69	5	3307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCell	droplet-Heart-nan-18m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM43B ADAMTS17 TRIM43 IRF6 CEMIP2	1.21e-05	192	69	5	0b9b2eaed45456d7d74ce78a64ef4a26ac2458fb
ToppCell	droplet-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFHR2 FBN1 MRC2 CSMD1 SVEP1	1.21e-05	192	69	5	38d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 MRC2 CSMD1 FST SVEP1	1.21e-05	192	69	5	853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	FBN1 LPCAT2 MRC2 ADAMTS17 SVEP1	1.21e-05	192	69	5	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFHR2 FBN1 MRC2 CSMD1 SVEP1	1.21e-05	192	69	5	04d155897ed075c359933080e36a4ab2150b6e9f
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFHR2 FBN1 MRC2 CSMD1 SVEP1	1.21e-05	192	69	5	84149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 MRC2 CSMD1 FST SVEP1	1.21e-05	192	69	5	49281626ecad0456fdbded2378b7028d7b589686
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	FNDC3B FBN1 LPCAT2 MRC2 SVEP1	1.24e-05	193	69	5	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	FNDC3B FBN1 LPCAT2 MRC2 SVEP1	1.27e-05	194	69	5	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POGLUT3 FBN1 MRC2 FST SVEP1	1.27e-05	194	69	5	bbc625b4cc53bb7d6254fde287258e51f9171572
ToppCell	facs-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POGLUT3 FBN1 MRC2 FST SVEP1	1.27e-05	194	69	5	fcd5e9238d299c41f0bf9693b56cd8c900d2112b
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	FNDC3B FBN1 LPCAT2 MRC2 SVEP1	1.27e-05	194	69	5	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 MRC2 SLITRK3 SVEP1 CNTFR	1.27e-05	194	69	5	35b30bc954750e939f81a9a7498b8bc2ce69a299
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 SEMA5B SLCO1A2 KLRG2 SLC44A4	1.27e-05	194	69	5	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell	LA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	FBN1 LPCAT2 ADAMTS17 FST SVEP1	1.27e-05	194	69	5	803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POGLUT3 FBN1 MRC2 FST SVEP1	1.27e-05	194	69	5	6afc21c5fec30ab8e373e3e46ab7866204c805b6
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	FNDC3B FBN1 LPCAT2 MRC2 SVEP1	1.30e-05	195	69	5	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 CTTNBP2 IGFBP1 SLCO1A2 KLRG2	1.34e-05	196	69	5	34e79918a448f6c19b87e1b1ce13c012b24be1f8
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 CTTNBP2 IGFBP1 SLCO1A2 KLRG2	1.34e-05	196	69	5	8f82e01ca50aa4cd6149547505b4474a02fad618
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	GJB2 FBN1 SEMA5B MRC2 FST	1.34e-05	196	69	5	eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high\|Trachea / Age, Tissue, Lineage and Cell class	FBN1 MRC2 THSD7B SVEP1 CNTFR	1.34e-05	196	69	5	54aefcebf13704f51de84379e2e22ec0734b9461
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FBN1 TIMP4 FST SVEP1 CNTFR	1.37e-05	197	69	5	3bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FBN1 TIMP4 FST SVEP1 CNTFR	1.37e-05	197	69	5	17344464fdcc5ba0c03959696b97c195f11e644c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFHR1 FBN1 MRC2 SVEP1 CNTFR	1.37e-05	197	69	5	4cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FBN1 TIMP4 FST SVEP1 CNTFR	1.37e-05	197	69	5	5b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	FBN1 MRC2 FST SVEP1 CNTFR	1.44e-05	199	69	5	fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 MRC2 FST SVEP1 CNTFR	1.44e-05	199	69	5	8d71e1fc92ee24deedf23fbb1a85a7fba0d8d436
ToppCell	Biopsy_Other_PF-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	FBN1 MRC2 FST SVEP1 CNTFR	1.47e-05	200	69	5	0aa316b71f195ecf17ee897e307f8928a755a637
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FNDC3B FBN1 MRC2 SVEP1 CNTFR	1.47e-05	200	69	5	ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCell	distal-mesenchymal-Adventitial_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FBN1 MRC2 SLITRK3 SVEP1 CNTFR	1.47e-05	200	69	5	687cfada2d0977e8985e0a73a5804f84f2ca9c52
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EGF SLCO1A2 ADAMTS17 XDH SLC44A4	1.47e-05	200	69	5	85c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLAMF8 CFHR1 GJB2 KLRG2	2.15e-05	105	69	4	cec0bdfe2bbd87c7e84671c1eeafad17aec1cdb2
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLAMF8 CFHR1 GJB2 KLRG2	2.15e-05	105	69	4	c4b3f085c7e372e529d2c5d275faba403e830d48
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLAMF8 CFHR1 GJB2 KLRG2	2.15e-05	105	69	4	dc5f6d62945a699734a71b8ab1d4266db6fb2918
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Solid_Pattern_Predominant_Adenocarcinoma\|TCGA-Lung / Sample_Type by Project: Shred V9	CFHR1 CFHR2 IGFBP1 F13B	2.98e-05	114	69	4	9c304f7a8584baccb591a873c67c5b57945cce44
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Solid_Pattern_Predominant_Adenocarcinoma-1\|TCGA-Lung / Sample_Type by Project: Shred V9	CFHR1 CFHR2 IGFBP1 F13B	3.08e-05	115	69	4	891a2c68472c2a633fc1864a9c3debc3b5ae1b77
ToppCell	droplet-Bladder-nan-3m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 TRAF2 ZSCAN20 WFIKKN2	3.52e-05	119	69	4	018162114bc22a9780fded5887f1f78211851700
ToppCell	LPS-IL1RA-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GJB2 SLCO1A2 BOP1 PGAP6	6.45e-05	139	69	4	505bf5a483fc2ba69377db9850c3b26ab2f416d1
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SELP CLEC2D XDH IRF6	6.45e-05	139	69	4	34398a6f21a1e670497655a7bb7f3cde9e117560
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SELP CLEC2D XDH IRF6	6.45e-05	139	69	4	450c4152c9fe4ec503271bb3cf93739918c59509
ToppCell	Fetal_29-31_weeks-Immune-mast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SELP EGF MYB GP9	7.60e-05	145	69	4	dc89d817a9bef24a07e992efdab4136f12ceb399
ToppCell	Healthy_donor-RBC\|World / disease group, cell group and cell class (v2)	UBE2O MRC2 KLRG2 CR1L	8.67e-05	150	69	4	1e1a497ec4b048f7e9cc12dd5dd9aba7fedca9e1
ToppCell	droplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFHR1 CFHR2 GJB2 F13B	8.90e-05	151	69	4	cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP TBC1D32 THSD7B GP9	8.90e-05	151	69	4	523dcd243c285a6b74830a93c82cca8784edd658
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELP TBC1D32 THSD7B GP9	8.90e-05	151	69	4	f3406094ce79cc80398b82d58ca6fd87a96e68d4
ToppCell	Healthy_donor-RBC\|Healthy_donor / disease group, cell group and cell class (v2)	UBE2O MRC2 KLRG2 CR1L	9.60e-05	154	69	4	e080d5104fe6f3f6ef617bbcdccf1332ab7231e1
ToppCell	COVID-19-Heart-CM_5_(RYR2-)\|Heart / Disease (COVID-19 only), tissue and cell type	IL12RB2 EGF ADAMTS17 CNTFR	9.84e-05	155	69	4	d7e26696fd9c0a759524f331243db43059b33ed9
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FAM20C FBN1 IGFBP1 MRC2	1.01e-04	156	69	4	bb505f639dbcad2b788db62d6084c2cb4e884bec
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFHR1 GJB2 IGFBP1 F13B	1.01e-04	156	69	4	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	PCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte1_(20)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SELP EGF CR1L GP9	1.06e-04	158	69	4	944c5fe625f965dd6153dbcbf5577f99ad343983
ToppCell	10x5'-Lung-Lymphocytic_NK-NK_CD56bright_CD16-\|Lung / Manually curated celltypes from each tissue	IL12RB2 ADAMTS17 FST CEMIP2	1.09e-04	159	69	4	595643e9433265308e5aab7f906229025701cf6a
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTTNBP2 MUC19 ODAD2 SVEP1	1.11e-04	160	69	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	Healthy/Control-RBC\|World / Disease group and Cell class	MRC2 KLRG2 CR1L ACE	1.11e-04	160	69	4	f10871238e7bdf3e1f65a17070000477196e50fe
ToppCell	wk_08-11-Hematologic-Meg-ery-Platelet\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SELP EGF CR1L GP9	1.11e-04	160	69	4	e0591f95f3f47ffbe013ebbebf6bed8c7c344732
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SELP GJB2 EGF GP9	1.11e-04	160	69	4	08696d93ff42a1beca23c70ab3e0d082cfff4aa7
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTTNBP2 MUC19 ODAD2 SVEP1	1.11e-04	160	69	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
Disease	Weill-Marchesani syndrome (implicated_via_orthology)	FBN1 ADAMTS17	1.57e-05	3	68	2	DOID:0050475 (implicated_via_orthology)
Disease	nephrotic syndrome (implicated_via_orthology)	FAT1 COQ2 ACE	2.29e-05	24	68	3	DOID:1184 (implicated_via_orthology)
Disease	Sjogren's syndrome (is_marker_for)	SELP MUC19 MUC5AC	2.29e-05	24	68	3	DOID:12894 (is_marker_for)
Disease	Weill-Marchesani syndrome	FBN1 ADAMTS17	3.13e-05	4	68	2	cv:C0265313
Disease	Weill-Marchesani syndrome (is_implicated_in)	FBN1 ADAMTS17	3.13e-05	4	68	2	DOID:0050475 (is_implicated_in)
Disease	complement factor H-related protein 2 measurement	CFHR1 CFHR2 F13B	4.10e-05	29	68	3	EFO_0600055
Disease	contactin-1 measurement	MUC19 PGAP6	7.80e-05	6	68	2	EFO_0020286
Disease	blood sedimentation	CR1 CR1L	1.09e-04	7	68	2	EFO_0004304
Disease	complement factor H-related protein 5 measurement	CFHR1 CFHR2 F13B	1.26e-04	42	68	3	EFO_0008098
Disease	mitral valve prolapse (is_implicated_in)	FBN1 ACE	1.86e-04	9	68	2	DOID:988 (is_implicated_in)
Disease	C3 glomerulopathy	CFHR1 CFHR2	1.86e-04	9	68	2	C4087273
Disease	cholestasis (biomarker_via_orthology)	SLCO1A2 XDH ACE	2.00e-04	49	68	3	DOID:13580 (biomarker_via_orthology)
Disease	complement factor H-related protein 1 measurement	CFHR1 CFHR2 F13B	2.97e-04	56	68	3	EFO_0600054
Disease	pancreatic ductal carcinoma (is_marker_for)	EGF ACE MUC5AC	3.83e-04	61	68	3	DOID:3587 (is_marker_for)
Disease	intermediate coronary syndrome (is_marker_for)	SELP ACE	4.02e-04	13	68	2	DOID:8805 (is_marker_for)
Disease	Depressed mood	SELP ACE	4.02e-04	13	68	2	C0344315
Disease	interstitial lung disease	THSD7B CSMD1 MUC5AC	5.05e-04	67	68	3	EFO_0004244
Disease	respiratory symptom measurement, COVID-19	FAT1 XDH CSMD1	6.75e-04	74	68	3	EFO_0007939, MONDO_0100096
Disease	renal fibrosis (implicated_via_orthology)	XDH ACE	6.96e-04	17	68	2	DOID:0050855 (implicated_via_orthology)
Disease	response to methotrexate, juvenile idiopathic arthritis	CTTNBP2 CSMD1	8.72e-04	19	68	2	EFO_0002609, GO_0031427
Disease	HbA1c measurement	FNDC3B EGF ASB16 TMEM131L CR2 PGAP6 MYB	9.20e-04	675	68	7	EFO_0004541
Disease	corneal hysteresis	FNDC3B FST	9.68e-04	20	68	2	EFO_0010066
Disease	QRS duration, response to sulfonylurea	CSMD1 COQ2	1.28e-03	23	68	2	EFO_0005055, EFO_0007922
Disease	Cancer of Head	FAT1 APOBEC3B	1.40e-03	24	68	2	C0751177
Disease	Head Neoplasms	FAT1 APOBEC3B	1.40e-03	24	68	2	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	FAT1 APOBEC3B	1.40e-03	24	68	2	C0887900
Disease	Calcium channel blocker use measurement	FAT1 SLC44A4 ACE SVEP1	1.50e-03	213	68	4	EFO_0009930
Disease	Neck Neoplasms	FAT1 APOBEC3B	1.52e-03	25	68	2	C0027533
Disease	Cancer of Neck	FAT1 APOBEC3B	1.52e-03	25	68	2	C0746787
Disease	platelet component distribution width	TRAF2 UBE2O EGF TMEM131L SVEP1 MYB GP9	1.75e-03	755	68	7	EFO_0007984
Disease	acute kidney failure (implicated_via_orthology)	XDH ACE	1.77e-03	27	68	2	DOID:3021 (implicated_via_orthology)
Disease	primary biliary cholangitis (biomarker_via_orthology)	SLCO1A2 ACE	1.90e-03	28	68	2	DOID:12236 (biomarker_via_orthology)
Disease	congestive heart failure (biomarker_via_orthology)	SELP TIMP4 ACE	1.96e-03	107	68	3	DOID:6000 (biomarker_via_orthology)
Disease	Liver Cirrhosis, Experimental	SYNRG INHBE FAT1 FBN1 IGFBP1 EGF CEMIP2	2.01e-03	774	68	7	C0023893
Disease	hair morphology	EGF CSMD1	2.04e-03	29	68	2	EFO_0005038
Disease	Thrombocytopenia	XDH GP9	2.04e-03	29	68	2	C0040034
Disease	Age related macular degeneration	CFHR1 CFHR2	2.18e-03	30	68	2	C0242383
Disease	forced expiratory volume	SLCO1A2 ADAMTS17 BOP1 SLC44A4 PPP6R2 SH2B1 SVEP1	2.24e-03	789	68	7	EFO_0004314

Protein segments in the cluster

Peptide	Gene	Start	Entry
AWNPSPAVCLVAAAV	BOP1	461	Q14137
WNDTIPSCVVPCSGN	CSMD1	1791	Q96PZ7
FVSWTPCPDCVAKLA	APOBEC3B	91	Q9UH17
PPSDVLNCENWTTLC	TBC1D32	201	Q96NH3
VCLPNKTATCWSLDP	ACE	156	P12821
NAYPCVPSCETWVEA	ASB16	371	Q96NS5
SACNVWRVCEGPKAV	CSDE1	731	O75534
LVKCNAWPCPNTVDC	GJB2	166	P29033
WTTCQKPETTNCVPQ	CST11	91	Q9H112
WCRAGECVSKTPIPE	ADAMTS17	526	Q8TE56
VSDPWEEKHTCVCPS	FAT1	3806	Q14517
WSAIKGSCDPSVCLP	COQ2	221	Q96H96
WCSREIPDPANSTCA	IL12RB2	661	Q99665
LLKANNPWPASTSCC	INHBE	301	P58166
ISRCEQGKWSSPPVC	F13B	436	P05160
APWQCAPCSAEKLAL	IGFBP1	26	P08833
NCCLWNTTVEVKACP	OIT3	111	Q8WWZ8
AVVQDCPKQTWCAEA	MUC19	8261	Q7Z5P9
NISCVERGWSTPPKC	CFHR2	126	P36980
QWSEPPKCLDPCVIS	CFHR2	196	P36980
SISQELKPWVCCAPQ	COPRS	136	Q9NQ92
WNDSPCNQSLPSICK	MRC2	491	Q9UBG0
LQPCSSTWEPASCGK	MYB	601	P10242
QPVTSDCHPLCAWTK	MUC5AC	4621	P98088
CVCAPDCSNITWKGP	FST	116	P19883
DQPAEPWACSQKFPC	PGAP6	741	Q9HCN3
WPFAAISTVCCPEKL	LPCAT2	81	Q7L5N7
WATAEATKDCPSPCT	GP9	11	P14770
VSWTPCPDCVAKLAE	APOBEC3F	91	Q8IUX4
PPDVTAKACQVCSAW	HEATR5A	1331	Q86XA9
LVAANCSTPRPWVCA	KLRG2	391	A4D1S0
GKWSAVPPTCEEARC	CR2	201	P20023
WSPAAPTCEVKSCDD	CR1	346	P17927
WSPAAPTCEVKSCDD	CR1	796	P17927
LWNSSVPVCEQIFCP	CR1	1761	P17927
CWIPVSSDKGSCPQV	EGF	1146	P01133
QAPSPCDPVCKIVDW	CTTNBP2	1296	Q8WZ74
CSCAQPAAEVAAPGW	FAM20C	46	Q8IXL6
AAWGSPCTLCQVDPI	FBN1	881	P35555
SPSACLVLNWEEPCN	FNDC3B	881	Q53EP0
GDWSPAAPRCEVKSC	CR1L	336	Q2VPA4
MAAPVPWACCAVLAA	CNTFR	1	P26992
PWACCAVLAAAAAVV	CNTFR	6	P26992
PSCVNVSKWNAVICS	CEMIP2	976	Q9UHN6
CTASGVWTAPAPVCK	SELP	306	P16109
VWTAPAPVCKAVQCQ	SELP	311	P16109
CVSSCPEDPWTVGKN	SLC44A4	116	Q53GD3
NISCVERGWSTPPKC	CFHR1	126	Q03591
PASPCAWNVCVTRKA	PPP6R2	801	O75170
CSVGNCSPEAVWPKT	IRF6	181	O14896
AWVSDIQECLSPGPC	SH2B1	366	Q9NRF2
LSWEEAQSPANCPAC	TRIM43	41	Q96BQ3
SIWAPQSDVYENCCP	TMEM131L	1536	A2VDJ0
ASCANFWINCVEPKP	SYNRG	1291	Q9UMZ2
HPDVKASAAWALCPC	ODAD2	851	Q5T2S8
ENPWDCTCDLVPFKQ	SLITRK3	561	O94933
DQVPCEKCGSLVPVW	POLH	631	Q9Y253
VDCNCPSKIWDPVCG	SLCO1A2	441	P46721
SSWSHSPPVCEPVKC	SVEP1	1891	Q4LDE5
CTAPVGLPDCWDAKE	STK36	666	Q9NRP7
CTHVQWDCASPDPAA	ADGRD2	146	Q7Z7M1
VPTGPWFCRKCESQE	MLLT10	61	P55197
EPSVCLQAACPESWI	CLEC2D	66	Q9UHP7
CECPEDPQAWQKTLS	POGLUT3	141	Q7Z4H8
ESLPAVCPSDGCTWK	TRAF2	101	Q12933
KCPTEAVCQPLDWGE	ZSCAN20	651	P17040
VEPAKIAWECPEKNC	UBE2O	361	Q9C0C9
VPCTISAPNECLWTD	TIMP4	166	Q99727
TLCVTGVPENCKPWS	XDH	1316	P47989
EALCATQACPEGWSP	SEMA5B	956	Q9P283
QPSKTCQVFLSCWAP	SLAMF8	141	Q9P0V8
LSWEEAQSPANCPAC	TRIM43B	41	A6NCK2
KDCIVTAFSEWTPCP	THSD7B	736	Q9C0I4
TQEKTCPVTPCYSWV	THSD7B	1291	Q9C0I4
VDWACPCPNVTVSEM	WFIKKN2	511	Q8TEU8