Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transcription coregulator activity	MIER2 TCERG1L RB1 CALCOCO1 CAMTA2 SIN3A ACSS2 SIRT1 USP21 NCOR2 PTPN14 MAMSTR MED13	1.15e-04	562	135	13	GO:0003712
GeneOntologyMolecularFunction	chromatin binding	ZNF609 CALCOCO1 CAMTA2 SIN3A ACSS2 SIRT1 WAC NCOR2 BRD2 NFIA SCML1 KMT2A PAX3 TCF7L1 BAHCC1	1.45e-04	739	135	15	GO:0003682
GeneOntologyMolecularFunction	transcription factor binding	ATF7 RB1 CAMTA2 SIN3A SOX8 GRM1 SIRT1 ADD1 NCOR2 NFIA KMT2A PAX3 VGLL4 MED13 DCP1A	1.78e-04	753	135	15	GO:0008134
MousePheno	perinatal lethality, incomplete penetrance	ANK2 RB1 LCP2 SIRT1 MEX3C BRD2 SYNJ1 KMT2A TSHZ1 PAX3 CAMSAP1 ALK CDON BAHCC1	1.66e-05	503	102	14	MP:0011090
Domain	C8	ZAN MUC6 OTOG	7.25e-05	12	132	3	PF08742
Domain	TIL	ZAN MUC6 OTOG	7.25e-05	12	132	3	PF01826
Domain	Unchr_dom_Cys-rich	ZAN MUC6 OTOG	9.37e-05	13	132	3	IPR014853
Domain	C8	ZAN MUC6 OTOG	9.37e-05	13	132	3	SM00832
Domain	TIL_dom	ZAN MUC6 OTOG	1.19e-04	14	132	3	IPR002919
Domain	fn3	COL7A1 SPEG OBSCN CMYA5 FNDC1 PTPRZ1 CDON	1.54e-04	162	132	7	PF00041
Domain	VWF_type-D	ZAN MUC6 OTOG	1.81e-04	16	132	3	IPR001846
Domain	VWFD	ZAN MUC6 OTOG	1.81e-04	16	132	3	PS51233
Domain	VWD	ZAN MUC6 OTOG	1.81e-04	16	132	3	SM00216
Domain	VWD	ZAN MUC6 OTOG	1.81e-04	16	132	3	PF00094
Domain	VWC_out	ZAN MUC6 OTOG	3.08e-04	19	132	3	SM00215
Domain	FN3	COL7A1 SPEG OBSCN CMYA5 FNDC1 PTPRZ1 CDON	3.47e-04	185	132	7	SM00060
Domain	FN3	COL7A1 SPEG OBSCN CMYA5 FNDC1 PTPRZ1 CDON	5.38e-04	199	132	7	PS50853
Domain	VWA	COL7A1 ANTXRL INTS6 VWA3B	6.59e-04	56	132	4	PF00092
Domain	FN3_dom	COL7A1 SPEG OBSCN CMYA5 FNDC1 PTPRZ1 CDON	7.19e-04	209	132	7	IPR003961
Domain	SH3	DOCK4 OBSCN SORBS1 ASAP2 CASKIN1 EPS8L3 ARHGAP33	8.73e-04	216	132	7	SM00326
Domain	SH3	DOCK4 OBSCN SORBS1 ASAP2 CASKIN1 EPS8L3 ARHGAP33	8.73e-04	216	132	7	PS50002
Domain	SH3_domain	DOCK4 OBSCN SORBS1 ASAP2 CASKIN1 EPS8L3 ARHGAP33	9.71e-04	220	132	7	IPR001452
Pathway	PID_RB_1PATHWAY	ATF7 RB1 SIRT1 BRD2 PAX3	3.70e-05	65	82	5	M279
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ZNF384 CRYBG2 LZTR1 OFD1 CTC1 SPEG OBSCN SLCO4A1 ADGRL1 POM121C C6orf132 PRR12 NCOR2 KANSL1 BRD2 CELSR3 SYNJ1 CASKIN1 SEC16A CAMSAP1 MYRF ULK2 MED13 ARHGAP33 BAHCC1	2.48e-12	1105	140	25	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF609 LZTR1 GNL3L RB1 ATXN7L1 ZNF362 SIN3A POM121C SIRT1 KSR1 NCOR2 INTS6 SETD2 PTPN14 BRD2 SCML1 SEC16A SAP130 TCF7L1 ARHGAP33 BAHCC1 ZNF646	7.88e-10	1116	140	22	31753913
Pubmed	Human transcription factor protein interaction networks.	ZNF609 OFD1 RB1 PHF23 ATXN7L1 DTNA RC3H1 SIN3A POM121C SIRT1 TLX1 PRR12 NCOR2 KANSL1 BRD2 NFIA SEC16A OTUD4 KMT2A VGLL4 SAP130 DCP1A	6.69e-08	1429	140	22	35140242
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SLCO4A1 SIN3A SIRT1 ADD1 NCOR2 SETD2 KANSL1 BRD2 NFIA SEC16A OTUD4 KMT2A RIMS1 MED13 DCP1A	5.93e-07	774	140	15	15302935
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK4 WHRN SPEG ADGRL1 SORBS1 CAMTA2 EPG5 KANSL1 SEC16A OTUD4 ULK2	8.66e-07	407	140	11	12693553
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	WHRN ATXN7L1 SORBS1 ASAP2 CELSR3 MED13 BAHCC1	1.03e-06	130	140	7	12421765
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	ZNF384 ZNF362 PRR12 NCOR2 NFIA SAP130	1.12e-06	83	140	6	28794006
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	ZNF609 PHF23 SIN3A GRM1 POM121C C6orf132 NCOR2 ASAP2 TSHZ1 CAMSAP1 SAP130	1.48e-06	430	140	11	35044719
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	ZNF609 ZNF362 SIN3A WAC PRR12 NFIA KMT2A SAP130 MED13	1.52e-06	268	140	9	33640491
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK4 OFD1 SORBS1 LARP1B MEX3C C6orf132 KSR1 PTPN14 SYNJ1 AMOT SEC16A KMT2A CAMSAP1 DCP1A OTOG	2.21e-06	861	140	15	36931259
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	OFD1 KIAA0586 LARP1B ADD1 SCML1 SEC16A CAMSAP1 DCP1A	2.25e-06	209	140	8	36779422
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	ATF7 ZNF384 TMEM201 RB1 ZNF362 SIN3A ADD1 NFIA OTUD4 PAX3 SAP130 ZNF646	4.58e-06	583	140	12	29844126
Pubmed	Proto-oncogene FBI-1 represses transcription of p21CIP1 by inhibition of transcription activation by p53 and Sp1.	SIN3A SIRT1 NCOR2	5.27e-06	9	140	3	19244234
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MIER2 RC3H1 KIAA0586 POM121C PTGFRN WAC PRR12 SETD2 ASAP2 NFIA FHDC1	5.45e-06	493	140	11	15368895
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	STRC STRCP1 OTOG	1.03e-05	11	140	3	31776257
Pubmed	Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.	WHRN STRC STRCP1	1.03e-05	11	140	3	31448880
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	ANK2 ADGRL1 NBEA SORBS1 ACSS2 ADD1 SYNJ1 CASKIN1 RIMS1	1.23e-05	347	140	9	17114649
Pubmed	Interaction network of human early embryonic transcription factors.	ZNF609 POM121C SIRT1 PRR12 NCOR2 NFIA SEC16A KMT2A BAHCC1	1.35e-05	351	140	9	38297188
Pubmed	Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.	LGMN SYNJ1	1.61e-05	2	140	2	33677035
Pubmed	SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemia.	SETD2 KMT2A	1.61e-05	2	140	2	29249820
Pubmed	MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.	SETD2 KMT2A	1.61e-05	2	140	2	29777171
Pubmed	Setd2 deficiency promotes gastric tumorigenesis through inhibiting the SIRT1/FOXO pathway.	SIRT1 SETD2	1.61e-05	2	140	2	37914019
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	1.61e-05	2	140	2	34910522
Pubmed	Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.	SPEG OBSCN	1.61e-05	2	140	2	15185077
Pubmed	NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1.	SIRT1 KMT2A	1.61e-05	2	140	2	25751424
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	1.61e-05	2	140	2	11687802
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ATF7 ZNF609 GNL3L ATXN7L1 DTNA CALCOCO1 OBSCN ADGRL1 ZNF362 LRCH3 NCOR2 INTS6 ASAP2 NFIA SLC9A7 VGLL4 RIMS1 SAP130	3.17e-05	1489	140	18	28611215
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	ZNF609 RB1 PRR12 NCOR2 BRD2 SYNJ1 SEC16A TSHZ1 BAHCC1	3.60e-05	398	140	9	35016035
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NYAP2 ANK2 CALCOCO1 NBEA SORBS1 GRM1 ADD1 NCOR2 SYNJ1 CASKIN1 SEC16A OTUD4 RIMS1 CAMSAP1	3.66e-05	963	140	14	28671696
Pubmed	Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.	STRC STRCP1 OTOG	4.17e-05	17	140	3	20856818
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	SPEG SORBS1 ADD1 PTPRZ1 CASKIN1 RIMS1 ARHGAP33	4.42e-05	231	140	7	16452087
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ATF7 FOXO6 RB1 PHF23 SIN3A NCOR2 KANSL1 NFIA TSHZ1 PAX3 CAMSAP1 SAP130 DCP1A	4.57e-05	857	140	13	25609649
Pubmed	HER2 regulates cancer stem-like cell phenotype in ALK translocated NSCLC.	ERBB3 ALK	4.81e-05	3	140	2	28656214
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	4.81e-05	3	140	2	30801007
Pubmed	Identification of functional cooperative mutations of SETD2 in human acute leukemia.	SETD2 KMT2A	4.81e-05	3	140	2	24509477
Pubmed	Anaplastic lymphoma kinase: "Ligand Independent Activation" mediated by the PTN/RPTPβ/ζ signaling pathway.	PTPRZ1 ALK	4.81e-05	3	140	2	23777859
Pubmed	Whole-exome mutational landscape of neuroendocrine carcinomas of the gallbladder.	RB1 ALK	4.81e-05	3	140	2	33563892
Pubmed	Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line.	ANK2 OBSCN	4.81e-05	3	140	2	18782775
Pubmed	A distal centriolar protein network controls organelle maturation and asymmetry.	OFD1 KIAA0586	4.81e-05	3	140	2	30258116
Pubmed	CTC1 OB-B interaction with TPP1 terminates telomerase and prevents telomere overextension.	ACD CTC1	4.81e-05	3	140	2	37021555
Pubmed	SIRT1 Activation Attenuates Bone Cancer Pain by Inhibiting mGluR1/5.	GRM1 SIRT1	4.81e-05	3	140	2	31270711
Pubmed	Shelterin Telomere Protection Protein 1 Reduction Causes Telomere Attrition and Cellular Senescence via Sirtuin 1 Deacetylase in Chronic Obstructive Pulmonary Disease.	ACD SIRT1	4.81e-05	3	140	2	27559927
Pubmed	Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.	ANK2 OBSCN	4.81e-05	3	140	2	12527750
Pubmed	Aberrant anaplastic lymphoma kinase activity induces a p53 and Rb-dependent senescence-like arrest in the absence of detectable p53 stabilization.	RB1 ALK	4.81e-05	3	140	2	21423761
Pubmed	Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage.	RB1 SIRT1	4.81e-05	3	140	2	16892051
Pubmed	Anaplastic lymphoma kinase is activated through the pleiotrophin/receptor protein-tyrosine phosphatase beta/zeta signaling pathway: an alternative mechanism of receptor tyrosine kinase activation.	PTPRZ1 ALK	4.81e-05	3	140	2	17681947
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF609 SOX8 PRR12 NCOR2 SYNJ1 AMOT SEC16A CAMSAP1 DCP1A	5.26e-05	418	140	9	34709266
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF609 NYAP2 LRCH1 FRMD4B CELSR3 AMOT CASKIN1 FAM149B1 MED13 ZNF646	5.98e-05	529	140	10	14621295
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ATF7 TMEM201 ZNF609 ACD SIN3A POM121C WAC PRR12 NCOR2 INTS6 SETD2 KANSL1 BRD2 NFIA KMT2A SAP130	6.91e-05	1294	140	16	30804502
Pubmed	FOXK2 Elicits Massive Transcription Repression and Suppresses the Hypoxic Response and Breast Cancer Carcinogenesis.	SIN3A NCOR2 SAP130	6.92e-05	20	140	3	27773593
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	ERBB3 SOX8 CELSR3 PTPRZ1 TSHZ1 PAX3 ALK	7.46e-05	251	140	7	29031500
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SIN3A ADD1 SETD2 PTPN14 SYNJ1 AMOT SEC16A KMT2A SAP130 DCP1A	8.13e-05	549	140	10	38280479
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	PMS2P5 COL7A1 CTC1 PODXL MUC16 ZNF362 POM121C PRR12 INTS6 EPS8L3	8.50e-05	552	140	10	10737800
Pubmed	Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.	SIN3A KMT2A ZBTB3 SAP130 BAHCC1	8.58e-05	110	140	5	26841866
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ZNF609 LZTR1 OFD1 DTNA TNS2 NBEA ZNF362 NCOR2 PTPN14 BRD2 PTPRZ1 SEC16A OTUD4 DCP1A	9.10e-05	1049	140	14	27880917
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	ZNF609 POM121C PRR12 NCOR2 NFIA SEC16A	9.35e-05	180	140	6	35198878
Pubmed	Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.	STRC STRCP1	9.60e-05	4	140	2	18849963
Pubmed	Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1.	RB1 SIRT1	9.60e-05	4	140	2	17620057
Pubmed	LRCH proteins: a novel family of cytoskeletal regulators.	LRCH1 LRCH3	9.60e-05	4	140	2	20805893
Pubmed	Distinct kinetic and mechanical properties govern mucin 16- and podocalyxin-mediated tumor cell adhesion to E- and L-selectin in shear flow.	PODXL MUC16	9.60e-05	4	140	2	26329844
Pubmed	The lymphoma-associated NPM-ALK oncogene elicits a p16INK4a/pRb-dependent tumor-suppressive pathway.	RB1 ALK	9.60e-05	4	140	2	21518927
Pubmed	Role of the histone deacetylase complex in acute promyelocytic leukaemia.	SIN3A NCOR2	9.60e-05	4	140	2	9486654
Pubmed	Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases.	ACSS2 SIRT1	9.60e-05	4	140	2	16790548
Pubmed	BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation.	PAX3 CDON	9.60e-05	4	140	2	11782431
Pubmed	ALK expression in rhabdomyosarcomas: correlation with histologic subtype and fusion status.	PAX3 ALK	9.60e-05	4	140	2	18788887
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	TMEM201 POM121C C6orf132 PTPN14 AMOT SEC16A CAMSAP1	9.97e-05	263	140	7	34702444
Pubmed	A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.	ANK2 DTNA SORBS1 NCOR2	1.03e-04	60	140	4	19075228
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ZNF384 GNL3L ANK2 SIN3A POM121C ADD1 WAC SETD2 SYNJ1 SEC16A KMT2A CAMSAP1 DCP1A	1.08e-04	934	140	13	33916271
Pubmed	BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.	ZNF609 NCOR2 SEC16A	1.21e-04	24	140	3	33722704
Pubmed	Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation.	ANK2 ACSS2 MYRF	1.38e-04	25	140	3	32266943
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	DOCK4 RB1 DTNA SORBS1 SIRT1 NCOR2 SETD2 PTPN14 SYNJ1 SEC16A	1.42e-04	588	140	10	38580884
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	ANK2 NBEA SORBS1 GRM1 ASAP2 SYNJ1 RIMS1	1.50e-04	281	140	7	28706196
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	OFD1 LRCH1 LRCH3 SYNJ1 SEC16A	1.57e-04	125	140	5	29467281
Pubmed	Thalamocortical control of cell-type specificity drives circuits for processing whisker-related information in mouse barrel cortex.	CELSR3 RIMS1	1.60e-04	5	140	2	37770450
Pubmed	Components of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6.	SIN3A NCOR2	1.60e-04	5	140	2	9765306
Pubmed	Interaction of the pRB-family proteins with factors containing paired-like homeodomains.	RB1 PAX3	1.60e-04	5	140	2	9464541
Pubmed	Activation of the c-myc p1 promoter in Burkitt's lymphoma by the hs3 immunoglobulin heavy-chain gene enhancer.	RB1 SIN3A	1.60e-04	5	140	2	17287852
Pubmed	Analysis of DNA copy number alterations in ovarian serous tumors identifies new molecular genetic changes in low-grade and high-grade carcinomas.	DOCK4 RB1	1.60e-04	5	140	2	19383911
Pubmed	Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells.	SIN3A NCOR2	1.60e-04	5	140	2	15729358
Pubmed	Prohibitin co-localizes with Rb in the nucleus and recruits N-CoR and HDAC1 for transcriptional repression.	RB1 SIN3A	1.60e-04	5	140	2	12466959
Pubmed	Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression.	SIN3A NCOR2	1.60e-04	5	140	2	10640276
Pubmed	Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma.	SIRT1 NCOR2	1.60e-04	5	140	2	15175761
Pubmed	Viral ski inhibits retinoblastoma protein (Rb)-mediated transcriptional repression in a dominant negative fashion.	RB1 SIN3A	1.60e-04	5	140	2	9988677
Pubmed	The WW domains dictate isoform-specific regulation of YAP1 stability and pancreatic cancer cell malignancy.	PTPN14 AMOT	1.60e-04	5	140	2	32292505
Pubmed	Neurofibromin deficiency in mice causes exencephaly and is a modifier for Splotch neural tube defects.	ERBB3 PAX3	1.60e-04	5	140	2	10419687
Pubmed	Pax7, Pax3 and Mamstr genes are involved in skeletal muscle impaired regeneration of dy2J/dy2J mouse model of Lama2-CMD.	MAMSTR PAX3	1.60e-04	5	140	2	31348492
Pubmed	The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis.	SEC16A ULK2	1.60e-04	5	140	2	27203176
Pubmed	An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.	STRC STRCP1	1.60e-04	5	140	2	24920589
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	DTNA SORBS1 ADD1 SYNJ1 RIMS1	1.75e-04	128	140	5	30995482
Pubmed	The functional interactome landscape of the human histone deacetylase family.	MIER2 ZNF609 RB1 SIN3A NCOR2 SEC16A SAP130	1.78e-04	289	140	7	23752268
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	MIER2 ZNF384 GNL3L RB1 ZNF362 SIN3A SIRT1 BRD2 NFIA KMT2A	1.86e-04	608	140	10	36089195
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRL1 ADGRG4 CELSR3	2.16e-04	29	140	3	15203201
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ANK2 CALCOCO1 ADGRL1 NBEA SORBS1 GRM1 ADD1 LRCH3 SYNJ1 PTPRZ1 AMOT CASKIN1 SEC16A OTUD4 KMT2A RIMS1	2.18e-04	1431	140	16	37142655
Pubmed	A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells.	RB1 SORBS1 SIRT1 VGLL4	2.21e-04	73	140	4	22094256
Pubmed	Myospryn is a novel binding partner for dysbindin in muscle.	DTNA CMYA5	2.39e-04	6	140	2	14688250
Pubmed	Genetic interaction of Pax3 mutation and canonical Wnt signaling modulates neural tube defects and neural crest abnormalities.	ERBB3 PAX3	2.39e-04	6	140	2	34490995
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC16 MUC6	2.39e-04	6	140	2	19110483
Pubmed	Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex.	RB1 SIN3A	2.39e-04	6	140	2	11909966
Pubmed	PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors.	SIN3A NCOR2	2.39e-04	6	140	2	11259580
Pubmed	NFIA and NFIB function as tumour suppressors in high-grade glioma in mice.	RB1 NFIA	2.39e-04	6	140	2	33346791
Interaction	YWHAH interactions	DOCK4 LGMN REM1 FOXO6 OFD1 SPEG TNS2 SORBS1 LARP1B MEX3C C6orf132 USP21 KSR1 SHROOM1 PTPN14 SYNJ1 AMOT SEC16A KMT2A RIMS1 CAMSAP1 DCP1A OTOG	9.62e-07	1102	134	23	int:YWHAH
Interaction	TOP3B interactions	ZNF384 CRYBG2 LZTR1 OFD1 CTC1 SPEG OBSCN SLCO4A1 ADGRL1 POM121C C6orf132 PRR12 NCOR2 KANSL1 BRD2 CELSR3 SYNJ1 CASKIN1 SEC16A OTUD4 CAMSAP1 MYRF ULK2 MED13 ARHGAP33 BAHCC1	3.77e-06	1470	134	26	int:TOP3B
Interaction	EGR2 interactions	ZNF609 SOX8 PRR12 NCOR2 NFIA SEC16A KMT2A BAHCC1	1.92e-05	171	134	8	int:EGR2
Interaction	GSC interactions	ZNF609 USP21 PRR12 NCOR2 NFIA BAHCC1	2.51e-05	87	134	6	int:GSC
Interaction	TLE3 interactions	ZNF609 ZNF362 WAC TLX1 PRR12 NCOR2 SETD2 NFIA OTUD4 KMT2A SAP130	4.37e-05	376	134	11	int:TLE3
Interaction	SMG7 interactions	ZNF609 OFD1 RC3H1 SIRT1 PRR12 NCOR2 AMOT SEC16A OTUD4 DCP1A	5.53e-05	319	134	10	int:SMG7
Interaction	ZYX interactions	ZNF384 ANK2 KIAA0586 SORBS1 SIRT1 PTPN14 AMOT SEC16A CAMSAP1 DCP1A	7.16e-05	329	134	10	int:ZYX
Interaction	PXN interactions	DOCK4 WHRN OFD1 SORBS1 ASAP2 PTPN14 SEC16A CAMSAP1 ALK DCP1A	8.11e-05	334	134	10	int:PXN
Interaction	YWHAE interactions	REM1 ACD RC3H1 TNS2 SORBS1 LCP2 LRCH1 FRMD4B MEX3C C6orf132 LRCH3 USP21 KSR1 NCOR2 PTPN14 KMT2A CAMSAP1 SAP130 ARHGAP33 DCP1A OTOG	8.31e-05	1256	134	21	int:YWHAE
Interaction	EN1 interactions	ZNF609 SIRT1 NCOR2 NFIA KMT2A SAP130	9.39e-05	110	134	6	int:EN1
Interaction	IRF2BP2 interactions	ERBB3 SIN3A TLX1 NCOR2 NFIA VGLL4	9.39e-05	110	134	6	int:IRF2BP2
GeneFamily	Fibronectin type III domain containing	COL7A1 OBSCN CMYA5 FNDC1 PTPRZ1 CDON	8.79e-05	160	82	6	555
Coexpression	RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN	LGMN ERBB3 OFD1 PODXL DTNA ZNF362 ADD1 LRCH3 KSR1 SETD2 KANSL1 NFIA SLC9A7 TSHZ1 VGLL4 FHDC1 ZBTB3 CDON	3.24e-07	807	140	18	M16651
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	DOCK4 TCERG1L ANK2 SPEG ADGRL1 NBEA SORBS1 SIN3A LARP1B GRM1 FRMD4B CELSR3 WDR97 SYNJ1 CASKIN1 SLC9A7 OTUD4 RIMS1 CDON	7.05e-06	1106	140	19	M39071
Coexpression	GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_UP	ERBB3 ADGRL1 ACSS2 LRCH1 KANSL1 SEC16A STRC CDON	1.22e-05	199	140	8	M5709
ToppCell	Ionocyte-iono-3\|World / Class top	COL7A1 CTC1 ADGRL1 SIN3A LARP1B TRMT44 AMOT	9.75e-07	166	140	7	9c4a780f8af46d7552077c7a0ae0ab1b2413e5d4
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MIER2 ATF7 CTC1 ADGRL1 TNS2 VGLL4 MED13	1.87e-06	183	140	7	3ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ANK2 SLCO4A1 HIF3A PTPN14 KANSL1 TCF7L1	2.40e-06	190	140	7	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Ciliated\|LPS_only / Treatment groups by lineage, cell group, cell type	TCTE1 PIH1D2 CFAP54 FRRS1 VWA3B CFAP70 ARHGAP33	3.15e-06	198	140	7	6d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	RB1 WAC KANSL1 SCML1 KMT2A TCF7L1 CDON	3.26e-06	199	140	7	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRC63 CCDC187 CFAP54 VWA3B CFAP70 ARHGAP33	1.59e-05	169	140	6	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REM1 PODXL SLCO4A1 MAMSTR FHDC1 ARHGAP33	1.64e-05	170	140	6	50c6c571591aa4b218caefe5778c570c809f567e
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REM1 PODXL SLCO4A1 MAMSTR FHDC1 ARHGAP33	1.64e-05	170	140	6	8fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REM1 PODXL SLCO4A1 MAMSTR FHDC1 ARHGAP33	1.64e-05	170	140	6	3232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell	ASK428-Immune-B_cell\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	WHRN GNL3L SLCO4A1 MUC16 ADD1 RIMS1	1.88e-05	174	140	6	b5a7a612a515736cf3489afd0f6ad2054d54526f
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	REM1 ANK2 OBSCN NBEA NFIA CDON	2.07e-05	177	140	6	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	wk_15-18-Epithelial-PNS-Schwann_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ERBB3 SOX8 PTPRZ1 CASKIN1 PAX3 ALK	2.07e-05	177	140	6	5357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERBB3 MUC16 NBEA CMYA5 KSR1 RIMS1	2.20e-05	179	140	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-4\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	GRM1 SPATA31C1 FNDC1 VGLL4 TCF7L1 CDON	2.27e-05	180	140	6	886ebaf9cf8992e8dd13fca799a1d1a2a9ce73d8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WHRN SLCO4A1 CMYA5 PTPRZ1 CASKIN1 PAX3	2.49e-05	183	140	6	25c96df8ea0c7bbedbb7699ee84ad6234d19cba8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WHRN PCDHB15 SLCO4A1 CMYA5 PTPRZ1 PAX3	2.49e-05	183	140	6	99bb4ceb92f6467f2359a42ab2cff6df18825a30
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4A1 CMYA5 FNDC1 CFAP54 PTPRZ1 PAX3	2.57e-05	184	140	6	6b0c110d8930df99043c3b99cf4d873985126960
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4A1 CMYA5 FNDC1 CFAP54 PTPRZ1 PAX3	2.57e-05	184	140	6	35928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WHRN SLCO4A1 CMYA5 PTPRZ1 CASKIN1 PAX3	2.65e-05	185	140	6	dbbd348714cd16a4948a04648e914b1e71e2a8ef
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WHRN SLCO4A1 CMYA5 PTPRZ1 CASKIN1 PAX3	2.65e-05	185	140	6	bea69058afa5aa927fe15c1f8d46460562ec4dd4
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK2 DTNA OBSCN SORBS1 CMYA5 NFIA	3.08e-05	190	140	6	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CRYBG2 ERBB3 CCDC187 EPS8L3 MYRF	3.17e-05	115	140	5	15b2c11225802cc15c01165d84a755432f02d82f
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	DOCK4 PODXL FRMD4B ADD1 ASAP2 VGLL4	3.36e-05	193	140	6	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	NS-critical-d_07-13-Epithelial-Secretory\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ERBB3 PODXL NFIA PTPRZ1 RIMS1 MYRF	3.46e-05	194	140	6	2172d951896265243d14996eacce5aab5e14e26e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIH1D2 MUC16 CCDC187 NBEA CFAP54 CFAP70	3.46e-05	194	140	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PODXL OBSCN SLCO4A1 SORBS1 HIF3A RIMS1	3.46e-05	194	140	6	40842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 NBEA CFAP54 VWA3B RIMS1 CFAP70	3.56e-05	195	140	6	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIH1D2 MUC16 NBEA VWA3B RIMS1 CFAP70	3.76e-05	197	140	6	d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCell	Bronchus_Control_(B.)\|World / Sample group, Lineage and Cell type	MUC16 NBEA CMYA5 INTS6 PTPRZ1 RIMS1	3.76e-05	197	140	6	b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PODXL MUC16 FAM221B PTPRZ1 PAX3 RIMS1	3.87e-05	198	140	6	28ada093cec552262731194a04a4b9ff93186c3b
ToppCell	Tracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	REM1 DTNA SPEG SORBS1 CMYA5 FNDC1	3.87e-05	198	140	6	cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TCTE1 CCDC187 CFAP54 PTPRZ1 VWA3B CFAP70	4.10e-05	200	140	6	96701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell	NS-critical-d_07-13-Epithelial-unknown_epithelial\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	COL7A1 MUC16 SOX8 INTS6 RIMS1	8.36e-05	141	140	5	33ad925ff7be3c682741a6328216a89f9d4033e9
ToppCell	PND01-03-samps-Epithelial-Epithelial-non_alveolar\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PIH1D2 CCDC187 CFAP54 VWA3B CFAP70	1.23e-04	153	140	5	fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	REM1 DTNA SPEG HIF3A FNDC1	1.23e-04	153	140	5	1524557514668f515ac1bbe847611f564b265b42
ToppCell	PND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PIH1D2 CCDC187 CFAP54 VWA3B CFAP70	1.23e-04	153	140	5	2482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ERBB3 TNS2 ZC3H12B CMYA5 PTPRZ1	1.30e-04	155	140	5	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	10x5'-Liver-Myeloid_Mac-Intestinal_macrophages\|Liver / Manually curated celltypes from each tissue	LGMN PTGFRN FRMD4B ASAP2 FRRS1	1.34e-04	156	140	5	9a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	MUC16 CCDC187 LINC01356 EPS8L3 CFAP70	1.34e-04	156	140	5	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTC1 SPEG FNDC1 SHROOM1 RIMS1	1.39e-04	157	140	5	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NYAP2 PTPRZ1 TSHZ1 VGLL4 ALK	1.39e-04	157	140	5	516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ERBB3 MUC16 NBEA PTPRZ1 RIMS1	1.56e-04	161	140	5	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	SORBS1 ZNF362 VSIR NFIA AMOT	1.60e-04	162	140	5	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PODXL KIAA0586 CELSR3 CFAP70 MYRF	1.60e-04	162	140	5	ca30d9bf61f4133566fdc91c7996e130ea554d01
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WHRN ZNF384 ZNF609 FOXO6 SHROOM1	1.65e-04	163	140	5	d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	WHRN LZTR1 OBSCN SLC9A7 CFAP70	1.85e-04	167	140	5	e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231\|Adult / Lineage, Cell type, age group and donor	PODXL OBSCN SLCO4A1 SORBS1 CELSR3	1.85e-04	167	140	5	5af9127bae05768a5164d5708a4ad37edca99324
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL7A1 REM1 TRMT44 RP1L1 GPAT2	1.90e-04	168	140	5	a8958b94ffc3423d56c250796dd253884b46f9d9
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	WHRN MUC16 NBEA CFAP54 CFAP70	1.95e-04	169	140	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK2 DTNA OBSCN SORBS1 CMYA5	2.01e-04	170	140	5	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	droplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LGMN TMEM201 SPEG FRMD4B PNPLA1	2.01e-04	170	140	5	f664c7559e383b37845c123e41a3be316d869ba0
ToppCell	Ciliated_cells-A-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	MUC16 NBEA FAM221B VWA3B CFAP70	2.01e-04	170	140	5	3d3a03979014df3a05c49be18010c6b94d786707
ToppCell	droplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LGMN TMEM201 SPEG FRMD4B PNPLA1	2.01e-04	170	140	5	0272eb1487c2545d4aa06f5d1cd77f823e1441e9
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERBB3 GNL3L DTNA PTPRZ1 OTUD4	2.06e-04	171	140	5	b51bbeacb172e8b5de519ada85543d7ae9914b3c
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PODXL OBSCN SLCO4A1 FRRS1 MAMSTR	2.06e-04	171	140	5	1ae4b6a25bc9c1065cf5d95998ebcc70aee21ab5
ToppCell	390C-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MIER2 ERBB3 TNS2 WDR97 EPS8L3	2.06e-04	171	140	5	70963f79711fe6088d6d01b29206b17ab89e5e73
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122\|Adult / Lineage, Cell type, age group and donor	PODXL OBSCN SLCO4A1 SORBS1 HIF3A	2.06e-04	171	140	5	bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PODXL SLCO4A1 HIF3A SHROOM1 PTPN14	2.06e-04	171	140	5	1597459c971d6befa991d59dc66b41b6a522f797
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM201 PHF23 SLCO4A1 LINC01356 CAMSAP1	2.06e-04	171	140	5	87d652afbb375f8ee50e5faecf6085630cd2163c
ToppCell	Ciliated_cells-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	MUC16 NBEA UROC1 CFAP54 CFAP70	2.12e-04	172	140	5	187ae91148d293537afc77e10da2b64302322224
ToppCell	critical-Epithelial-unknown_epithelial\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	LCP2 INTS6 BRD2 SCML1 DCP1A	2.18e-04	173	140	5	4144b1cdefa8c37b6ac7a6d249fa5292ffb2b8b2
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PIH1D2 CCDC187 CFAP54 VWA3B CFAP70	2.23e-04	174	140	5	f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRC63 ANK2 ADGRL1 ZNF362 GPAT2	2.23e-04	174	140	5	9bb8159a62640756d18ecbade3bf32bcbb7dd590
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 EPG5 ASAP2 AMOT RIMS1	2.23e-04	174	140	5	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRC63 ANK2 ADGRL1 ZNF362 GPAT2	2.23e-04	174	140	5	e70cc623a3a6aceec813ed852fec0c4240561133
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	MUC16 NBEA PTPRZ1 RIMS1 CDON	2.23e-04	174	140	5	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRC63 ANK2 ADGRL1 ZNF362 GPAT2	2.23e-04	174	140	5	b6725086fe5a2b057c7c495ec63c970ac52c2580
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FOXO6 MUC16 FNDC1 SYNJ1 CDON	2.23e-04	174	140	5	4da79da7a09ee1e345102c5331675ebcdbe56171
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PIH1D2 CCDC187 CFAP54 VWA3B CFAP70	2.29e-04	175	140	5	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell	ASK428-Immune-B_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	WHRN SLCO4A1 MUC16 ADD1 RIMS1	2.29e-04	175	140	5	e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PODXL PCDHB15 SORBS1 PTPRZ1 VGLL4	2.29e-04	175	140	5	e99e145a152f534b75267ec492a252a0b814b4f8
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL7A1 REM1 PTPN14 ARHGAP33 BAHCC1	2.36e-04	176	140	5	27e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK2 DTNA OBSCN SORBS1 CMYA5	2.36e-04	176	140	5	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 NBEA CFAP54 VWA3B CFAP70	2.36e-04	176	140	5	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WHRN LGMN LCP2 VSIR ZBTB3	2.42e-04	177	140	5	201b0a8e6402a18aff0bb7c14f2bdd34fdf0db32
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DTNA SPEG SORBS1 HIF3A FNDC1	2.42e-04	177	140	5	b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WHRN LGMN LCP2 VSIR ZBTB3	2.42e-04	177	140	5	2a63288d09efd217b277aeecf957811a095f56e7
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WHRN LGMN LCP2 VSIR ZBTB3	2.42e-04	177	140	5	56fe389ffab73e3bc64f837b152d5907e3517a91
ToppCell	Ciliated_cells-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	PIH1D2 CCDC187 CFAP54 VWA3B CFAP70	2.42e-04	177	140	5	c38138fb5ad9766c2d240811210c854338cd612e
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ERBB3 PTPRZ1 SLC9A7 FHDC1 ALK	2.42e-04	177	140	5	59726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	WHRN CTC1 FNDC1 PTPRZ1 AMOT	2.48e-04	178	140	5	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PODXL MUC16 VSIR MYRF CDON	2.55e-04	179	140	5	056df2aaff750e0e283e7da78fcc3c90c366aac0
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PODXL MUC16 VSIR MYRF CDON	2.55e-04	179	140	5	f5f3945ef3b9efc5921a71fd51deeb2c80f0ce11
ToppCell	ILEUM-non-inflamed-(7)_Lymphatics\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANK2 PODXL CMYA5 NFIA AMOT	2.55e-04	179	140	5	99777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DTNA NCOR2 CELSR3 PTPRZ1 ALK	2.61e-04	180	140	5	c72f15763ba707189e29c85db533557f01c7fdb1
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	NBEA C6orf132 RGS14 KSR1 CFAP70	2.61e-04	180	140	5	12f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	NBEA C6orf132 RGS14 KSR1 CFAP70	2.61e-04	180	140	5	1bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	NBEA C6orf132 RGS14 KSR1 CFAP70	2.61e-04	180	140	5	2a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PODXL MUC16 VSIR MYRF CDON	2.68e-04	181	140	5	3dcb74b28f93be35ddf4de1937f7e30b25e11927
ToppCell	PCW_10-12-Neuronal-Neuronal_postreplicative\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 ANK2 SOX8 PTPRZ1 ALK	2.68e-04	181	140	5	1aebb62ed4439db444ee9d30688212b86ee3d9ef
ToppCell	PCW_10-12-Neuronal-Neuronal_postreplicative-neuro_NA\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 ANK2 SOX8 PTPRZ1 ALK	2.68e-04	181	140	5	6aee2ddee4790250ef3b2ef0038bd9839925c995
ToppCell	PCW_10-12-Neuronal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 ANK2 SOX8 PTPRZ1 ALK	2.68e-04	181	140	5	381b553e2cae65ce6be100662a5f9f963353840c
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK2 DTNA OBSCN SORBS1 CMYA5	2.68e-04	181	140	5	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PODXL MUC16 VSIR MYRF CDON	2.68e-04	181	140	5	7679a5980011d6dfb1aaca7abf678c29b6f819bb
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4A1 CMYA5 FNDC1 PTPRZ1 PAX3	2.75e-04	182	140	5	904804813849b7f7f716ba1554d33b07bc0a701e
ToppCell	facs-Heart-LV-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4A1 SIRT1 RGS14 BRD2 ULK2	2.75e-04	182	140	5	6dff753d65ba45db81f3cc0c9f59e1779d490955
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4A1 CMYA5 FNDC1 PTPRZ1 PAX3	2.75e-04	182	140	5	5d8b7fe18286e27f0f50c5d2d9be56850e2cb8f4
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LRRC63 ERBB3 SOX8 FRMD4B MYRF	2.82e-04	183	140	5	5472cdce6d99314d229418412acf1fff6340db7d
ToppCell	(7)_DC_plasmacytoid\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	LGMN ZAN FAM221B ASAP2 BAHCC1	2.82e-04	183	140	5	2c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LRRC63 ERBB3 SOX8 FRMD4B MYRF	2.89e-04	184	140	5	a2191dd5546efd357b23e625beb3c5820476f243
Drug	Pseudopelletierine hydrochloride [6164-62-1]; Up 200; 21uM; MCF7; HT_HG-U133A	REM1 CALCOCO1 ADGRL1 CAMTA2 ZNF362 HIF3A ALK ARHGAP33 BAHCC1	3.12e-06	197	137	9	2766_UP
Drug	Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; PC3; HT_HG-U133A	ZNF609 DTNA ZNF362 LRCH1 ADD1 SLC9A7 ALK ARHGAP33	2.44e-05	195	137	8	6626_UP
Drug	Pipenzolate bromide [125-51-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A	CRYBG2 RB1 DTNA SORBS1 CAMTA2 SYNJ1 ALK ARHGAP33	2.53e-05	196	137	8	6821_UP
Drug	L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A	MIER2 CRYBG2 REM1 C19orf73 RGS14 KSR1 NCOR2 RIMS1	2.63e-05	197	137	8	6497_UP
Drug	Calciferol [50-14-6]; Up 200; 10uM; PC3; HT_HG-U133A	CRYBG2 ZNF609 DTNA LCP2 PAX3 RIMS1 CAMSAP1 ALK	2.72e-05	198	137	8	6746_UP
Drug	Fluocinonide [356-12-7]; Down 200; 8uM; MCF7; HT_HG-U133A	GNL3L DTNA CALCOCO1 ADD1 SETD2 OTUD4 KMT2A ZBTB3	2.72e-05	198	137	8	3414_DN
Drug	Verapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A	RB1 SORBS1 ZNF362 GRM1 RGS14 KSR1 PTPN14 KMT2A	2.72e-05	198	137	8	5387_UP
Drug	Isradipine [75695-93-1]; Up 200; 10.8uM; HL60; HT_HG-U133A	COL7A1 CTC1 ZNF362 GRM1 C19orf73 RGS14 KSR1 MYRF	2.82e-05	199	137	8	3129_UP
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	2.08e-05	2	135	2	DOID:0110471 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	COL7A1 ERBB3 ANK2 RB1 PCDHB15 OBSCN SORBS1 SIRT1 EPG5 SETD2 PTPN14 TMEM39A ZBTB3 ALK TCF7L1 ZNF646	3.39e-05	1074	135	16	C0006142
Disease	Atypical juvenile parkinsonism	PODXL SYNJ1	6.21e-05	3	135	2	C4510873
Disease	Neurodevelopmental Disorders	ANK2 WAC SETD2 KMT2A RIMS1	7.00e-05	93	135	5	C1535926
Disease	monocyte percentage of leukocytes	ATF7 CRYBG2 NYAP2 CALCOCO1 ADD1 KSR1 SETD2 KANSL1 SEC16A GPAT2 CD300E BAHCC1	1.41e-04	731	135	12	EFO_0007989
Disease	Crohn's disease	TCERG1L ANK2 HIF3A RGS14 KSR1 BRD2 CELSR3 MAMSTR MYRF	2.04e-04	441	135	9	EFO_0000384
Disease	Intellectual Disability	NBEA SIN3A UROC1 WAC PRR12 SETD2 KANSL1 NFIA MED13	2.25e-04	447	135	9	C3714756
Disease	anorexia nervosa	ERBB3 CELSR3 TSHZ1 VGLL4	3.04e-04	70	135	4	MONDO_0005351
Disease	renal overload-type gout	SPATA31C2 SPATA31C1	3.08e-04	6	135	2	EFO_0021525
Disease	eye disease (implicated_via_orthology)	RP1L1 MYRF	3.08e-04	6	135	2	DOID:5614 (implicated_via_orthology)
Disease	Orofaciodigital Syndromes	OFD1 FAM149B1	3.08e-04	6	135	2	C0029294
Disease	temporal lobe epilepsy (biomarker_via_orthology)	GRM1 ADD1 PTPRZ1	3.83e-04	31	135	3	DOID:3328 (biomarker_via_orthology)
Disease	age at diagnosis, osteoarthritis	KANSL1 RP1L1	4.30e-04	7	135	2	EFO_0004918, MONDO_0005178
Disease	alcohol dependence measurement, electroencephalogram measurement	UROC1 FRMD4B	4.30e-04	7	135	2	EFO_0004357, EFO_0007835
Disease	Brain Tumor, Primary	SIRT1 AMOT ALK	4.62e-04	33	135	3	C0750974
Disease	Primary malignant neoplasm of brain	SIRT1 AMOT ALK	4.62e-04	33	135	3	C0750979
Disease	Recurrent Brain Neoplasm	SIRT1 AMOT ALK	4.62e-04	33	135	3	C0750977
Disease	Benign neoplasm of brain, unspecified	SIRT1 AMOT ALK	4.62e-04	33	135	3	C0496899
Disease	Neoplasms, Intracranial	SIRT1 AMOT ALK	4.62e-04	33	135	3	C1527390
Disease	obesity (implicated_via_orthology)	GNL3L SIRT1 PNPLA1 SEC16A TCF7L1 MED13	4.80e-04	215	135	6	DOID:9970 (implicated_via_orthology)
Disease	sexual dimorphism measurement	COL7A1 NYAP2 FOXO6 PHF23 PODXL SPATA31C2 ACSS2 SPATA31C1 NCOR2 PNPLA1 CASKIN1 SEC16A OTUD4 MYRF	5.62e-04	1106	135	14	EFO_0021796
Disease	eosinophil cationic protein measurement	SPATA31C2 SPATA31C1	5.71e-04	8	135	2	EFO_0010913
Disease	Acute erythroleukemia - M6a subtype	RB1 KMT2A	5.71e-04	8	135	2	C2930975
Disease	Acute myeloid leukemia FAB-M6	RB1 KMT2A	5.71e-04	8	135	2	C2930976
Disease	Acute erythroleukemia - M6b subtype	RB1 KMT2A	5.71e-04	8	135	2	C2930977
Disease	Acute erythroleukemia	RB1 KMT2A	5.71e-04	8	135	2	C2930974
Disease	Malignant neoplasm of brain	SIRT1 AMOT ALK	7.03e-04	38	135	3	C0153633
Disease	longitudinal alcohol consumption measurement	SPATA31C2 SPATA31C1	7.32e-04	9	135	2	EFO_0007645
Disease	Brain Neoplasms	SIRT1 AMOT ALK	7.59e-04	39	135	3	C0006118
Disease	hematocrit	NYAP2 ZAN SORBS1 PRR12 RGS14 NCOR2 PNPLA1 NFIA PSORS1C1 MAMSTR SLC9A7 MYRF BAHCC1	7.71e-04	1011	135	13	EFO_0004348
Disease	serum gamma-glutamyl transferase measurement	NYAP2 POM121C USP21 NCOR2 SETD2 RP1L1 SLC9A7 KMT2A TSHZ1 MUC6 MED13 BAHCC1	1.03e-03	914	135	12	EFO_0004532
Disease	Gastric Adenocarcinoma	ERBB3 SPEG BRD2	1.15e-03	45	135	3	C0278701
Disease	QRS-T angle	SPEG KANSL1 NFIA KMT2A	1.45e-03	106	135	4	EFO_0020097
Disease	egg allergy measurement, parental genotype effect measurement	SPATA31C2 SPATA31C1	1.57e-03	13	135	2	EFO_0005939, EFO_0007018
Disease	glucose-dependent insulinotropic peptide measurement	NBEA FRMD4B NCOR2	1.86e-03	53	135	3	EFO_0008464
Disease	BMI-adjusted adiponectin measurement	NYAP2 ALK	2.10e-03	15	135	2	EFO_0007737
Disease	Neoplasm of uncertain or unknown behavior of bladder	ERBB3 RB1	2.10e-03	15	135	2	C0496930
Disease	Benign neoplasm of bladder	ERBB3 RB1	2.10e-03	15	135	2	C0154017
Disease	Carcinoma in situ of bladder	ERBB3 RB1	2.10e-03	15	135	2	C0154091
Disease	creatinine measurement	ATF7 NYAP2 FOXO6 SPEG OBSCN SIN3A RGS14 PTPN14 CELSR3 NFIA PSORS1C1 CFAP70	2.10e-03	995	135	12	EFO_0004518
Disease	hair colour measurement	NYAP2 FOXO6 PODXL ATXN7L1 EPG5 PTPN14 NFIA PAX3 VGLL4	2.14e-03	615	135	9	EFO_0007822
Disease	amygdala volume change measurement	SPATA31C2 SPATA31C1	2.39e-03	16	135	2	EFO_0021490
Disease	Dyskeratosis Congenita	ACD CTC1	2.39e-03	16	135	2	C0265965
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	SETD2 MED13	2.70e-03	17	135	2	DOID:0060307 (is_implicated_in)
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	RB1 SETD2 KMT2A	2.78e-03	61	135	3	C1961102
Disease	Carcinoma of bladder	ERBB3 RB1	3.03e-03	18	135	2	C0699885
Disease	Systemic Scleroderma	SIRT1 PSORS1C1	3.38e-03	19	135	2	C0036421
Disease	eosinophil count	ERBB3 ATXN7L1 ZNF362 LCP2 PTGFRN WAC RGS14 NCOR2 SETD2 FNDC1 KANSL1 SEC16A VWA3B MYRF BAHCC1	3.40e-03	1488	135	15	EFO_0004842
Disease	diastolic blood pressure, systolic blood pressure	ANK2 SPEG LRCH1 ADD1 PSORS1C1 SEC16A VWA3B TCF7L1 DCP1A	3.78e-03	670	135	9	EFO_0006335, EFO_0006336
Disease	dentures	MAMSTR ALK BAHCC1	4.10e-03	70	135	3	EFO_0010078
Disease	dental caries, dentures	MAMSTR ALK BAHCC1	4.10e-03	70	135	3	EFO_0003819, EFO_0010078
Disease	Sarcoma	RB1 PAX3	4.12e-03	21	135	2	C1261473
Disease	serum copper measurement	ANK2 VWA3B	4.12e-03	21	135	2	EFO_0005267

Protein segments in the cluster

Peptide	Gene	Start	Entry
RHSLLTPVTPLSPPG	ERBB3	1136	P21860
ALHPTKPPVPVISSA	EPG5	1511	Q9HCE0
PTQLVILPSEPTPHS	BAHCC1	871	Q9P281
PPSTRLSPARHPLVP	AMOT	326	Q4VCS5
VPPPPILLSRTHCSV	CFAP54	906	Q96N23
PHSLPAAPTLATPTL	CCDC187	866	A0A096LP49
SPLLRHTAEPPLSLP	ANTXRL	611	A6NF34
SFPPETTISIPLPHI	CTC1	996	Q2NKJ3
VTPSTHTLVCSKPPP	ADGRG4	1136	Q8IZF6
VPSTRRPPAPNLHVS	ADGRL1	461	O94910
ITTPRRTTHPATPPI	CD300E	131	Q496F6
PRALTLTSIPHAHPP	CAMTA2	256	O94983
PTPTIVRPGSLPLHL	ATF7	146	P17544
PPPEVSRSAHVPSLQ	ACSS2	31	Q9NR19
HAPTYTIPLSPVLSP	DCP1A	306	Q9NPI6
KTPTPSVETLPHLRP	CAMSAP1	1121	Q5T5Y3
LPSPAAHITTPVPAS	ATXN7L1	516	Q9ULK2
RPVITGPRASPHATP	NFIA	351	Q12857
YASTRPPTLSPIPHI	RB1	771	P06400
SISALPVNPHSIPPR	RC3H1	546	Q5TC82
VHLTPAVPSLPATVP	OTUD4	581	Q01804
PTLPPRTSHPVVKFS	INTS6	296	Q9UL03
PLPSPTESRHSLSIP	OFD1	771	O75665
VSPSGRTEKHPPVSP	ANK2	1916	Q01484
SHLRPEPPKPRVSSL	FAM47C	736	Q5HY64
SVPSVPHELPRVPSF	FHDC1	1021	Q9C0D6
TPSTLPPFTITHPVE	MUC16	2446	Q8WXI7
VPTTLPESRPSSPVH	MUC16	6526	Q8WXI7
PESRPSSPVHLTSLP	MUC16	6531	Q8WXI7
PVSTTFLAHIPPSPL	MUC16	7701	Q8WXI7
RPPSSPITTQLPHLS	MUC6	2101	Q6W4X9
PTSPVTNLTTRHPGP	MUC6	2296	Q6W4X9
SEPRPLVPPVSGHAT	NCOR2	1976	Q9Y618
EHLTTPHPTSPLSPR	PODXL	176	O00592
PLSPRQPTSTHPVAT	PODXL	186	O00592
EKPSSHLPPTPRATT	CASKIN1	676	Q8WXD9
SITPVPAKSRNPHPR	TCTE1	41	Q5JU00
RPRSVPSIHVPSPAV	LRCH3	696	Q96II8
PTRSPPGPHTAVLAL	LRP10	671	Q7Z4F1
TRIPTEHLLRGSPPP	LZTR1	266	Q8N653
PTAEARPHVARSPPT	MED14OS	36	P0DP75
AVHPPLPPLRVTSTN	ASAP2	826	O43150
TPRALHSFITPPTTP	KSR1	261	Q8IVT5
PIAAPVSIPRPHLLT	FAM205A	656	Q6ZU69
PIAAPVSIPRPHLLT	FAM205BP	386	Q63HN1
SPLVPSPSQIPLEAH	FAM221B	56	A6H8Z2
SLPPSPRPLPRHTSA	EPS8L3	201	Q8TE67
APPAPSRSALAHPIS	FOXO6	366	A8MYZ6
AKLTPRSTPPHPCSL	PMS2P5	101	A8MQ11
PARSLHSQAPTSPRP	PNPLA1	411	Q8N8W4
SPISPELHSAPLTPV	KANSL1	991	Q7Z3B3
PRSVASIHVPSPAVP	LRCH1	621	Q9Y2L9
HISRDLSATVPSPPP	LRRC63	191	Q05C16
SRSSPSVPHSTPRPV	NYAP2	466	Q9P242
PSHIPIPKSSLITPT	PTPRZ1	966	P23471
LPPRDPHLPLTSLVS	PCDHB15	491	Q9Y5E8
VSDPSSTVHRPQPLP	PAX3	321	P23760
PTPAPASTIKIVPAH	POM121C	986	A8CG34
IPRIPESSHPPLESS	RIMS1	696	Q86UR5
AKSLPPSPVTHSPLL	OBSCN	6806	Q5VST9
TPTPALSPGRSLRPH	ARHGAP33	821	O14559
PPVLEALSPPHTLSS	C6orf132	191	Q5T0Z8
RSSSVPHSPRILPPK	FRMD4B	601	Q9Y2L6
RRPVPLPHSLSIPVT	DOCK4	1911	Q8N1I0
LPHSLSIPVTSEPPA	DOCK4	1916	Q8N1I0
PLHPVQGSPLETPRS	CFAP70	126	Q5T0N1
PTLPPVSHLTKPFSA	FRRS1	181	Q6ZNA5
TTPIPTCPPGTLERH	FNDC1	1506	Q4ZHG4
PASPHSVLPDSVPAI	CMYA5	1166	Q8N3K9
VPDAPIILSPPQTHT	CDON	576	Q4KMG0
VPSSPRLETHVPSPG	CRYBG2	351	Q8N1P7
QTPSPAGPRLHLSPT	GPAT2	761	Q6NUI2
RELHAAPPPATPTQT	C19orf73	41	Q9NVV2
SVKPSAASHRPPLPR	MAMSTR	241	Q6ZN01
PRSSPSHTISRPIPM	DTNA	561	Q9Y4J8
LHPPTPPILSTDRSR	KMT2A	1841	Q03164
TTPPEAPPALGTLHV	COL7A1	861	Q02388
RPVLPTHPALTLPVS	C1orf127	331	Q8N9H9
THVLLPSQSPRPSPS	CELSR3	2361	Q9NYQ7
RVPSAATTPPLPSHL	GRM1	981	Q13255
SPLVVISQPAPISPH	CALCOCO1	571	Q9P1Z2
TIHLRSSPSLPPASP	MENT	291	Q9BUN1
LPTAVPESPRIHPTR	LARP1B	586	Q659C4
PESPRIHPTRTPKTP	LARP1B	591	Q659C4
ESPAVPLSHRPPALA	MIER2	436	Q8N344
TPLHRRASTPLPLSP	REM1	11	O75628
SPRTPTHRPALTPAA	OTOG	1501	Q6ZRI0
PPPRTLHPISTSHSC	FAM149B1	421	Q96BN6
HVGPSARPPPSLSLR	PTGFRN	146	Q9P2B2
EDPILSRTPSPVHPS	SCML1	171	Q9UN30
VIPKTSPHCPLTTPR	TRMT44	186	Q8IYL2
TPPPLRDSTLLTPSH	SPATA31C2	231	B4DYI2
PPPRSRSSHSLPSEA	SYNJ1	1286	O43426
IPPPATHTLPTHLSA	GNL3L	401	Q9NVN8
PSTPLATRHPQSPLS	HIF3A	431	Q9Y2N7
SPTSTVVVIPSIPHP	NBEA	1606	Q8NFP9
TPSQLLIEPHPPRSS	NBEA	2551	Q8NFP9
TPRLSPTFPESIEHP	MEX3C	541	Q5U5Q3
PRPRPATSTPDLASH	PTPN14	571	Q15678
RSPPVQPHTPVTISL	SIN3A	276	Q96ST3
PARPPATHPRSASLS	SHROOM1	176	Q2M3G4
RPVALIPSSIPHEVP	SIRT1	446	Q96EB6
KPVVHPTATPSTVPS	WAC	251	Q9BTA9
PRVQSPPHLKSPSAE	WHRN	681	Q9P202
ASPTETGPPRPHIKT	SOX8	326	P57073
APRPTSHARPPSTSL	MED13	756	Q9UHV7
PSHIIRPLQSPPATG	PRR12	561	Q9ULL5
VSPLASPDPRTKHPQ	SPATA31C1	161	P0DKV0
VPLPRASQPSAHISP	STRC	326	Q7RTU9
HTPPSRRASPGTPLS	SLCO4A1	26	Q96BD0
LTPRSPHASRTPSSP	ACD	326	Q96AP0
VSHTALYTPPPEIPT	BRD2	221	P25440
CIVSPTPEPHLPLSL	ALK	1021	Q9UM73
RAAVVTSPPPTTAPH	ADD1	6	P35611
LSSHRTGPPPISPSK	VGLL4	41	Q14135
LPPSSTVELVPVFPH	TCERG1L	126	Q5VWI1
IPAPQSTTHPVPLTV	PIH1D2	76	Q8WWB5
PPHYPTLLTVPASVS	ZNF384	46	Q8TF68
PPTLFSIRTEPPASH	USP21	166	Q9UK80
PAPSPEHSSPSVRLL	SEC16A	1936	O15027
TPTSPHRRTQEPVLP	SPEG	331	Q15772
RPAEPTLPSTHVTPS	SPEG	2856	Q15772
VIHSRSPPGSTPRLP	RP1L1	261	Q8IWN7
PTSGIPHPAIVSPIV	TCF7L1	301	Q9HCS4
VPHAPVRTPSLSPVE	UROC1	26	Q96N76
TPIPTHSCPLSPDLI	TMEM39A	256	Q9NV64
HFSQSPRVTVPIPPT	WDR97	941	A6NE52
RHLLSEPSTPLSPPG	VSIR	276	Q9H7M9
PRSVASPLALPSPHK	SORBS1	1046	Q9BX66
ATPVAVTAPPAHLTP	SAP130	116	Q9H0E3
VTAPPAHLTPAVPLS	SAP130	121	Q9H0E3
SRPTLSIQHPPSAAI	SAP130	316	Q9H0E3
PLPPPSGIHLSASRT	PSORS1C1	116	Q9UIG5
TPKVRLVEPHSPSPS	ZNF609	566	O15014
PRPSVHVPVSSPLTQ	ZNF609	1206	O15014
PSVPPAPLLLAETTH	ZNF646	436	O15015
ATHPPPASPSSLVKV	RGS14	471	O43566
LFPTSPSLAIPHPSV	TMEM201	396	Q5SNT2
HTSRPPAALTPVPLS	PHF23	156	Q9BUL5
VTALSVPTIPPPKSH	ZC3H12B	466	Q5HYM0
APVTEPVALPHTPIT	SETD2	206	Q9BYW2
TVSPHSETAPIPVPT	ULK2	391	Q8IYT8
HPQPLATGLPTVPSV	TLX1	146	P31314
VPAPQSLPSTTRPHL	LINC01356	71	Q8N9X3
EKIRPPHLPPTSASS	ZNF362	51	Q5T0B9
VPLPRASQPSAHISP	STRCP1	326	A6NGW2
SHAIIATPPPRAALP	VWA3B	1261	Q502W6
PILTHSGPPLTTTLP	SLC9A7	611	Q96T83
QSIPLPPTTHTRLPA	TSHZ1	466	Q6ZSZ6
PRSPVPTTLPGLRHA	TNS2	1001	Q63HR2
PHPVTVTTSIPPSSR	KIAA0586	756	Q9BVV6
KLTALRPPHPSPTAT	ZAN	996	Q9Y493
LVTSPLPAPASLHEP	ZBTB3	436	Q9H5J0
PLPPTTERHERSSPL	LCP2	286	Q13094
SSPVPLPPVTHLDLT	LGMN	291	Q99538
TVTALPLHPTRAPSP	MYRF	281	Q9Y2G1