Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

NPR1 POLA1 CDK19 PBK DYRK1A CAMK1 PDPK2P POLR3C MYO3A TAOK3 TRNT1 DGKK PANK4 POLI PEAK1 MAPK9 TOP1

5.64e-0593812217GO:0016772
GeneOntologyMolecularFunctionnitric-oxide synthase binding

DNM3 DNM1 DNM2

3.15e-04221223GO:0050998
GeneOntologyMolecularFunctiontestosterone 6-beta-hydroxylase activity

CYP3A7 CYP3A4

3.66e-0451222GO:0050649
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

NPR1 CDK19 PBK DYRK1A CAMK1 PDPK2P MYO3A TAOK3 DGKK PANK4 PEAK1 MAPK9 TOP1

4.01e-0470912213GO:0016773
GeneOntologyMolecularFunctionprotein serine/threonine kinase binding

DNM3 DNM1 DNM2

4.10e-04241223GO:0120283
GeneOntologyMolecularFunctionWD40-repeat domain binding

CDC5L USP47

5.47e-0461222GO:0071987
GeneOntologyMolecularFunctionD2 dopamine receptor binding

DNM1 DNM2

7.62e-0471222GO:0031749
GeneOntologyMolecularFunctionkinase activity

NPR1 CDK19 PBK DYRK1A CAMK1 PDPK2P MYO3A TAOK3 DGKK PANK4 PEAK1 MAPK9 TOP1

8.05e-0476412213GO:0016301
GeneOntologyMolecularFunctionestrogen 2-hydroxylase activity

CYP3A7 CYP3A4

1.01e-0381222GO:0101021
GeneOntologyMolecularFunctionprotein kinase activity

NPR1 CDK19 PBK DYRK1A CAMK1 PDPK2P MYO3A TAOK3 PEAK1 MAPK9 TOP1

1.14e-0360012211GO:0004672
GeneOntologyMolecularFunctionaromatase activity

CYP3A7 CYP2E1 CYP3A4

1.26e-03351223GO:0070330
GeneOntologyMolecularFunctionoxygen binding

CYP3A7 CYP2E1 CYP3A4

1.49e-03371223GO:0019825
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CHD9 ERCC6L2 CHD6

1.49e-03371223GO:0140658
GeneOntologyBiologicalProcesslipid hydroxylation

CYP3A7 CYP2E1 CYP3A4

1.61e-0591213GO:0002933
GeneOntologyBiologicalProcesscellular response to UV

CUL4B POLA1 PBK POLI MAPK9 USP47

2.30e-05971216GO:0034644
GeneOntologyBiologicalProcesssynaptic vesicle budding from presynaptic endocytic zone membrane

DNM3 DNM1 DNM2

3.14e-05111213GO:0016185
GeneOntologyBiologicalProcessresponse to UV

CUL4B POLA1 PBK CASP7 POLI MAPK9 USP47

5.86e-051671217GO:0009411
GeneOntologyBiologicalProcesssynaptic vesicle budding

DNM3 DNM1 DNM2

8.51e-05151213GO:0070142
GeneOntologyBiologicalProcessvesicle scission

DNM1 DNM2

1.02e-0431212GO:0099050
GeneOntologyBiologicalProcessvesicle-mediated transport in synapse

CLSTN1 EFR3A ITSN2 DNM3 RAB7A RNF216 RIMS1 DNM1 DNM2

1.18e-043211219GO:0099003
GeneOntologyBiologicalProcesscellular response to light stimulus

CUL4B POLA1 PBK POLI MAPK9 USP47

1.19e-041301216GO:0071482
GeneOntologyBiologicalProcesscellular response to radiation

CUL4B POLA1 PBK ECT2 POLI MAPK9 USP47

1.49e-041941217GO:0071478
GeneOntologyCellularComponentsynaptic membrane

CYTH1 RTN4 GRIA3 CLSTN1 KCNA1 SYDE2 ITSN2 SCN8A DNM3 RIMS1 GRIN3A DNM1 DNM2

4.02e-0558312313GO:0097060
GeneOntologyCellularComponentphotoreceptor inner segment

CDH23 MYO3A DNM3 DNM1 DNM2

9.74e-05781235GO:0001917
GeneOntologyCellularComponentglutamatergic synapse

RTN4 GRIA3 CAMK1 CLSTN1 EFR3A KCNA1 SCN8A DNM3 RAB7A RNF216 RIMS1 GRIN3A DNM1 DNM2

3.24e-0481712314GO:0098978
GeneOntologyCellularComponentpostsynaptic density

RTN4 GRIA3 CAMK1 PDPK2P CLSTN1 SCN8A DNM3 RIMS1 GRIN3A DNM2

3.39e-0445112310GO:0014069
GeneOntologyCellularComponentasymmetric synapse

RTN4 GRIA3 CAMK1 PDPK2P CLSTN1 SCN8A DNM3 RIMS1 GRIN3A DNM2

5.25e-0447712310GO:0032279
DomainDynamin_central

DNM3 DNM1 DNM2

5.23e-0661213IPR000375
DomainGED

DNM3 DNM1 DNM2

5.23e-0661213SM00302
DomainDynamin_M

DNM3 DNM1 DNM2

5.23e-0661213PF01031
DomainGED_dom

DNM3 DNM1 DNM2

5.23e-0661213IPR020850
DomainGED

DNM3 DNM1 DNM2

5.23e-0661213PS51388
DomainDynamin_GTPase_CS

DNM3 DNM1 DNM2

5.23e-0661213IPR019762
DomainGED

DNM3 DNM1 DNM2

5.23e-0661213PF02212
DomainGED

DNM3 DNM1 DNM2

5.23e-0661213IPR003130
DomainG_DYNAMIN_1

DNM3 DNM1 DNM2

9.11e-0671213PS00410
DomainDYNc

DNM3 DNM1 DNM2

9.11e-0671213SM00053
DomainKinase-like_dom

NPR1 CDK19 PBK DYRK1A CHD9 CAMK1 MYO3A TAOK3 DNM3 PEAK1 DNM1 MAPK9 DNM2

5.03e-0554212113IPR011009
DomainG_DYNAMIN_dom

DNM3 DNM1 DNM2

9.16e-05141213IPR030381
DomainG_DYNAMIN_2

DNM3 DNM1 DNM2

9.16e-05141213PS51718
Domain-

ARID3A ARID3B ARID1B

1.14e-041512131.10.150.60
DomainDynamin_GTPase

DNM3 DNM1 DNM2

1.14e-04151213IPR001401
DomainBRIGHT

ARID3A ARID3B ARID1B

1.14e-04151213SM00501
DomainARID_dom

ARID3A ARID3B ARID1B

1.14e-04151213IPR001606
DomainARID

ARID3A ARID3B ARID1B

1.14e-04151213PS51011
DomainDynamin_SF

DNM3 DNM1 DNM2

1.14e-04151213IPR022812
DomainDynamin_N

DNM3 DNM1 DNM2

1.14e-04151213PF00350
DomainARID

ARID3A ARID3B ARID1B

1.14e-04151213PF01388
DomainREKLES

ARID3A ARID3B

1.24e-0431212PS51486
DomainREKLES_domain

ARID3A ARID3B

1.24e-0431212IPR023334
DomainIQ_motif_EF-hand-BS

IQGAP2 MYO5C MYO3A MYO15B SCN8A

2.98e-04901215IPR000048
DomainIQ

IQGAP2 MYO5C MYO3A MYO15B SCN8A

3.46e-04931215PS50096
DomainCyt_P450_E_grp-II

CYP3A7 CYP3A4

4.11e-0451212IPR002402
DomainPH

ARHGAP23 CYTH1 ECT2 DGKK ITSN2 DNM3 DNM1 DNM2

4.59e-042781218SM00233
DomainPH_DOMAIN

ARHGAP23 CYTH1 ECT2 DGKK ITSN2 DNM3 DNM1 DNM2

4.70e-042791218PS50003
DomainPH_domain

ARHGAP23 CYTH1 ECT2 DGKK ITSN2 DNM3 DNM1 DNM2

4.82e-042801218IPR001849
DomainBRK

CHD9 CHD6

6.14e-0461212SM00592
DomainCyt_P450_E_CYP3A

CYP3A7 CYP3A4

6.14e-0461212IPR008072
DomainBRK_domain

CHD9 CHD6

6.14e-0461212IPR006576
DomainBRK

CHD9 CHD6

6.14e-0461212PF07533
Domain-

ARHGAP23 CYTH1 ECT2 RANBP3L DGKK ITSN2 DNM3 DNM1 DNM2

1.01e-0339112192.30.29.30
DomainSNF2_N

CHD9 ERCC6L2 CHD6

1.15e-03321213IPR000330
DomainSNF2_N

CHD9 ERCC6L2 CHD6

1.15e-03321213PF00176
DomainIQ

IQGAP2 MYO5C MYO3A SCN8A

1.17e-03711214PF00612
DomainP-loop_NTPase

SAMD9 DNAH2 CHD9 MYO5C MYO3A MYO15B DYNC2LI1 ERCC6L2 DNM3 RAB7A CHD6 DNM1 MPP7 DNM2

1.18e-0384812114IPR027417
DomainPH_dom-like

ARHGAP23 CYTH1 ECT2 RANBP3L DGKK ITSN2 DNM3 DNM1 DNM2

1.83e-034261219IPR011993
DomainMyosin_head_motor_dom

MYO5C MYO3A MYO15B

1.90e-03381213IPR001609
DomainMYOSIN_MOTOR

MYO5C MYO3A MYO15B

1.90e-03381213PS51456
DomainMyosin_head

MYO5C MYO3A MYO15B

1.90e-03381213PF00063
DomainMYSc

MYO5C MYO3A MYO15B

1.90e-03381213SM00242
DomainIQ

IQGAP2 MYO5C MYO3A SCN8A

1.90e-03811214SM00015
DomainPeripla_BP_I

NPR1 GRIA3 GRIN3A

2.04e-03391213IPR028082
DomainS_TKc

CDK19 PBK DYRK1A CAMK1 MYO3A TAOK3 PEAK1 MAPK9

2.36e-033591218SM00220
DomainSH3_2

STAC3 MYO15B ITSN2 MPP7

2.36e-03861214PF07653
DomainSH3_2

STAC3 MYO15B ITSN2 MPP7

2.36e-03861214IPR011511
DomainL27

PATJ MPP7

3.10e-03131212SM00569
DomainL27

PATJ MPP7

3.10e-03131212PS51022
DomainL27_dom

PATJ MPP7

3.10e-03131212IPR004172
DomainPkinase

CDK19 PBK DYRK1A CAMK1 MYO3A TAOK3 PEAK1 MAPK9

3.39e-033811218PF00069
DomainPH

CYTH1 DGKK ITSN2 DNM3 DNM1 DNM2

3.79e-032291216PF00169
DomainC2_dom

SYT15 SYT15B SYDE2 ITSN2 RIMS1

4.31e-031641215IPR000008
DomainProt_kinase_dom

NPR1 CDK19 PBK DYRK1A CAMK1 MYO3A TAOK3 PEAK1 MAPK9

4.56e-034891219IPR000719
DomainPROTEIN_KINASE_DOM

NPR1 CDK19 PBK DYRK1A CAMK1 MYO3A TAOK3 PEAK1 MAPK9

4.81e-034931219PS50011
DomainCyt_P450_CS

CYP3A7 CYP2E1 CYP3A4

4.91e-03531213IPR017972
DomainLig_chan-Glu_bd

GRIA3 GRIN3A

5.95e-03181212PF10613
DomainGlu/Gly-bd

GRIA3 GRIN3A

5.95e-03181212IPR019594
DomainLig_chan-Glu_bd

GRIA3 GRIN3A

5.95e-03181212SM00918
DomainIontro_rcpt

GRIA3 GRIN3A

5.95e-03181212IPR001320
DomainIono_rcpt_met

GRIA3 GRIN3A

5.95e-03181212IPR001508
DomainLig_chan

GRIA3 GRIN3A

5.95e-03181212PF00060
DomainPBPe

GRIA3 GRIN3A

5.95e-03181212SM00079
DomainCYTOCHROME_P450

CYP3A7 CYP2E1 CYP3A4

6.02e-03571213PS00086
Domainp450

CYP3A7 CYP2E1 CYP3A4

6.32e-03581213PF00067
PathwayREACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING

DNM3 DNM1 DNM2

8.14e-0514883M10122
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

CYP3A7 CYP2E1 CYP3A4 AOX1 ALDH1A3

8.51e-0572885M9257
PathwayREACTOME_RAC1_GTPASE_CYCLE

IQGAP2 ARHGAP23 ECT2 TAOK3 SYDE2 RAB7A MPP7

1.10e-04175887MM15599
PathwayREACTOME_RAC1_GTPASE_CYCLE

IQGAP2 ARHGAP23 ECT2 TAOK3 SYDE2 RAB7A MPP7

1.50e-04184887M41809
Pubmed

Dynamin: characteristics, mechanism of action and function.

DNM3 DNM1 DNM2

4.53e-083125312511974
Pubmed

Dynamin and endocytosis.

DNM3 DNM1 DNM2

4.53e-083125312383797
Pubmed

Disruption of the coxsackievirus and adenovirus receptor-homodimeric interaction triggers lipid microdomain- and dynamin-dependent endocytosis and lysosomal targeting.

DNM3 DNM1 DNM2

4.53e-083125324273169
Pubmed

Developmental expression of the dynamin family of mechanoenzymes in the mouse epididymis.

DNM3 DNM1 DNM2

4.53e-083125328395327
Pubmed

Dynamin at the actin-membrane interface.

DNM3 DNM1 DNM2

4.53e-083125312517701
Pubmed

Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors.

DNM3 DNM1 DNM2

4.53e-083125324046449
Pubmed

Overlapping role of dynamin isoforms in synaptic vesicle endocytosis.

DNM3 DNM1 DNM2

1.81e-074125321689597
Pubmed

Trans-infection but not infection from within endosomal compartments after cell-to-cell HIV-1 transfer to CD4+ T cells.

DNM3 DNM1 DNM2

1.81e-074125322846998
Pubmed

Growth factor-dependent phosphorylation of the actin-binding protein cortactin is mediated by the cytoplasmic tyrosine kinase FER.

DNM3 DNM1 DNM2

4.51e-07512539722593
Pubmed

Molecular components required for resting and stimulated endocytosis of botulinum neurotoxins by glutamatergic and peptidergic neurons.

DNM3 DNM1 DNM2

8.99e-076125323640057
Pubmed

Dynamin 1- and 3-Mediated Endocytosis Is Essential for the Development of a Large Central Synapse In Vivo.

DNM3 DNM1 DNM2

8.99e-076125327251629
Pubmed

A clathrin-dynamin-dependent endocytic pathway for the uptake of HIV-1 by direct T cell-T cell transmission.

DNM3 DNM1 DNM2

8.99e-076125318602423
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

CUL4B IQGAP2 NPEPPS RTN4 PBK PSMD3 ARID3B PPP2R5C SUPT6H PANK4 COG5 DNM2

9.14e-075601251235241646
Pubmed

A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis.

DNM3 DNM1 DNM2

1.57e-067125315252009
Pubmed

Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily.

DNM3 DNM1 DNM2

2.50e-068125324282027
Pubmed

Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses.

DNM3 RIMS1 DNM1 DNM2

2.62e-0627125419723784
Pubmed

Major histocompatibility complex class-II molecules promote targeting of human immunodeficiency virus type 1 virions in late endosomes by enhancing internalization of nascent particles from the plasma membrane.

DNM3 DNM1 DNM2

3.75e-069125323170932
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

IQGAP2 ARHGAP23 NPEPPS RTN4 DYRK1A PSMD3 ACTR3B KCNA1 ITSN2 RAB7A CORO6 RIMS1 PEAK1 CDC5L DNM1 TOP1 AGTPBP1 DNM2

3.78e-0614311251837142655
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

CUL4B CASC3 RTN4 PPIL4 PSMD3 POLR3C TYW5 SUPT6H PANK4 CDC5L DNM2 RBM17

4.44e-066531251233742100
Pubmed

Nomenclature of the ARID family of DNA-binding proteins.

ARID3A ARID3B ARID1B

5.34e-0610125315922553
Pubmed

Protein partners of dynamin-1 in the retina.

DNM3 DNM1 DNM2

5.34e-0610125323746204
Pubmed

Expression and localisation of dynamin and syntaxin during neural development and neuromuscular synapse formation.

DNM3 DNM1 DNM2

5.34e-0610125310398046
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

CYP2E1 PBX4 ACTR3B ECT2 MYO3A FSTL1 KLHL23 PANK4 GRIN3A PATJ SDK1 USP6NL MPP7

7.92e-068141251323251661
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

CUL4B SLF1 PPIL4 BCOR ARID3B ARID1B TAF3 ANKRD11 NKX2-5 MLLT6 CDC5L TOP1 KNL1 RBM17

9.07e-069541251436373674
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CASC3 IQGAP2 NPEPPS CYTH1 DYRK1A GRIA3 BCOR KCNA1 DNM3 RAB7A RIMS1 CDC5L DNM1 DNM2

1.01e-059631251428671696
Pubmed

Overexpression of the transcriptional repressor complex BCL-6/BCoR leads to nuclear aggregates distinct from classical aggresomes.

BCL6 BCOR

1.28e-052125224146931
Pubmed

Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7.

CYP3A7 CYP3A4

1.28e-052125228986474
Pubmed

Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation.

DNM1 DNM2

1.28e-052125221670293
Pubmed

Differential appearance of dynamin in constitutive and regulated exo-endocytosis: a single-cell multiplex RT-PCR study.

DNM1 DNM2

1.28e-052125216028072
Pubmed

Dynamics of Cytosine Methylation in the Proximal Promoters of CYP3A4 and CYP3A7 in Pediatric and Prenatal Livers.

CYP3A7 CYP3A4

1.28e-052125226772622
Pubmed

Dynamin is primed at endocytic sites for ultrafast endocytosis.

DNM3 DNM1

1.28e-052125235809574
Pubmed

Dynamin regulates L cell secretion in human gut.

DNM1 DNM2

1.28e-052125234274446
Pubmed

A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis.

DNM3 DNM1

1.28e-052125224963135
Pubmed

Crystal structure of the dynamin tetramer.

DNM3 DNM1

1.28e-052125226302298
Pubmed

Expression of CYP3A4 and CYP3A7 in Human Foetal Tissues and its Correlation with Nuclear Receptors.

CYP3A7 CYP3A4

1.28e-052125225689036
Pubmed

Immunohistochemical markers of CYP3A4 and CYP3A7: a new tool towards personalized pharmacotherapy of hepatocellular carcinoma.

CYP3A7 CYP3A4

1.28e-052125227349315
Pubmed

Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients.

CYP2E1 CYP3A4

1.28e-052125217119944
Pubmed

Genetic variants in 5p13.2 and 7q21.1 are associated with treatment for benign prostatic hyperplasia with the α-adrenergic receptor antagonist.

CYP3A4 RANBP3L

1.28e-052125228787260
Pubmed

An intramolecular signaling element that modulates dynamin function in vitro and in vivo.

DNM1 DNM2

1.28e-052125219515832
Pubmed

Prilocaine- and lidocaine-induced methemoglobinemia is caused by human carboxylesterase-, CYP2E1-, and CYP3A4-mediated metabolic activation.

CYP2E1 CYP3A4

1.28e-052125223530020
Pubmed

Oculo-facio-cardio-dental syndrome with craniosynostosis, temporal hypertrichosis, and deafness.

BCL6 BCOR

1.28e-052125228317252
Pubmed

The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family.

ARID3A ARID3B

1.28e-05212528543152
Pubmed

Classical dynamin DNM1 and DNM3 genes attain maximum expression in the normal human central nervous system.

DNM3 DNM1

1.28e-052125224673776
Pubmed

Dynamin regulates specific membrane fusion events necessary for acrosomal exocytosis in mouse spermatozoa.

DNM1 DNM2

1.28e-052125222977254
Pubmed

ARID3A and ARID3B induce stem promoting pathways in ovarian cancer cells.

ARID3A ARID3B

1.28e-052125232061921
Pubmed

Differential regulation of CYP3A4 and CYP3A7 by dimethylsulfoxide in primary human hepatocytes.

CYP3A7 CYP3A4

1.28e-052125215379787
Pubmed

Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR.

BCL6 BCOR

1.28e-052125215004558
Pubmed

Recurrent BCOR internal tandem duplication and BCOR or BCL6 expression distinguish primitive myxoid mesenchymal tumor of infancy from congenital infantile fibrosarcoma.

BCL6 BCOR

1.28e-052125228256570
Pubmed

Dynamin GTPase regulation is altered by PH domain mutations found in centronuclear myopathy patients.

DNM3 DNM1

1.28e-052125220700106
Pubmed

Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny.

CYP3A7 CYP3A4

1.28e-052125226921389
Pubmed

Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine.

CYP3A7 CYP3A4

1.28e-052125211940601
Pubmed

The Structural and Functional Integrity of Rod Photoreceptor Ribbon Synapses Depends on Redundant Actions of Dynamins 1 and 3.

DNM3 DNM1

1.28e-052125238641407
Pubmed

An NH2-terminal truncated cytochrome P450 CYP3A4 showing catalytic activity is present in the cytoplasm of human liver cells.

CYP2E1 CYP3A4

1.28e-052125218446064
Pubmed

Dynamin-mediated lipid acquisition is essential for Chlamydia trachomatis development.

DNM1 DNM2

1.28e-052125225116793
Pubmed

Dynamin at actin tails.

DNM1 DNM2

1.28e-052125211782545
Pubmed

X-linked BCOR variants identified in Chinese Han patients with congenital heart disease.

BCL6 BCOR

1.28e-052125236314054
Pubmed

Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses.

DNM3 DNM1

1.28e-052125222308498
Pubmed

Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer.

BCL6 BCOR

1.28e-052125218280243
Pubmed

Dynamin 2-dependent endocytosis is essential for mouse oocyte development and fertility.

DNM1 DNM2

1.28e-052125232065700
Pubmed

Developmental regulation of CYP3A4 and CYP3A7 in Chinese Han population.

CYP3A7 CYP3A4

1.28e-052125227727071
Pubmed

Expression and cyclic variability of CYP3A4 and CYP3A7 isoforms in human endometrium and cervix during the menstrual cycle.

CYP3A7 CYP3A4

1.28e-052125212485945
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

BCL6 CMYA5 ECT2 AKTIP ARID1B FSTL1 SUPT6H ENO3 AGTPBP1 DNM2

1.33e-054971251023414517
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

POLA1 DNAH2 PBX4 STOX1 ECT2 ERLEC1 MYO15B RANBP3L SYDE2 SCN8A CHD6 MAPK9

1.47e-057361251229676528
Pubmed

Human transcription factor protein interaction networks.

SLF1 ARID3A PPIL4 PSMD3 BCOR MYO5C ARID3B ARID1B TAF3 MRPL15 DGKK RAB7A NKX2-5 MLLT6 CHD6 TOP1 RAI2

1.49e-0514291251735140242
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CYTH1 DYRK1A LAMB1 CHD9 CAMK1 ACTR3B CMYA5 DNM3 RNF216 CHD6 PJA1 DNM1 TOP1 AGTPBP1 USP47 DNM2

1.56e-0512851251635914814
Pubmed

Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation.

DNM3 DNM1 DNM2

1.60e-0514125320802490
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SAMD9 ARHGAP23 RTN4 CLSTN1 ECT2 TAOK3 RNF216 CHPF2 DNM1 PATJ DNM2

2.42e-056501251138777146
Pubmed

EHBP1L1, an apicobasal polarity regulator, is critical for nuclear polarization during enucleation of erythroblasts.

DNM3 DNM1 DNM2

2.97e-0517125337042948
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

IQGAP2 DYRK1A BCOR TAOK3 ARID1B TRNT1 PPP2R5C TMEM131L PJA1 PEAK1 PATJ COG5 DNM2 LRRC17

3.71e-0510841251411544199
Pubmed

Detection of anti-isoniazid and anti-cytochrome P450 antibodies in patients with isoniazid-induced liver failure.

CYP2E1 CYP3A4

3.84e-053125223775837
Pubmed

ARID proteins come in from the desert.

ARID3A ARID3B

3.84e-053125210838570
Pubmed

The P450 oxidoreductase genotype is associated with CYP3A activity in vivo as measured by the midazolam phenotyping test.

CYP3A7 CYP3A4

3.84e-053125219801957
Pubmed

Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer--The Rotterdam Study.

CYP3A7 CYP3A4

3.84e-053125220621111
Pubmed

SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis.

DNM1 DNM2

3.84e-053125215703209
Pubmed

The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor.

BCL6 BCOR

3.84e-053125211777915
Pubmed

Lipid droplet breakdown requires dynamin 2 for vesiculation of autolysosomal tubules in hepatocytes.

DNM1 DNM2

3.84e-053125224145164
Pubmed

The Expression of Dynamin 1, 2, and 3 in Human Hepatocellular Carcinoma and Patient Prognosis.

DNM3 DNM2

3.84e-053125232573516
Pubmed

Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver.

CYP2E1 MAPK9

3.84e-053125222749809
Pubmed

Cytochrome P450 3As gene expression and testosterone 6 beta-hydroxylase activity in human fetal membranes and placenta at full term.

CYP3A7 CYP3A4

3.84e-053125220118548
Pubmed

BCOR as a novel fusion partner of retinoic acid receptor alpha in a t(X;17)(p11;q12) variant of acute promyelocytic leukemia.

BCL6 BCOR

3.84e-053125220807888
Pubmed

DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease.

DYRK1A MAPK9

3.84e-053125217906291
Pubmed

Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane.

DNM1 DNM2

3.84e-053125222371560
Pubmed

Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F‑dependent transcription via direct binding to E2F target genes.

ARID3A ARID3B

3.84e-053125233649863
Pubmed

A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.

BCL6 BCOR

3.84e-053125223911289
Pubmed

Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes.

CYP3A7 CYP3A4

3.84e-053125223143891
Pubmed

Development of template systems for ligand interactions of CYP3A5 and CYP3A7 and their distinctions from CYP3A4 template.

CYP3A7 CYP3A4

3.84e-053125233866277
Pubmed

Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase.

DNM1 DNM2

3.84e-053125215895076
Pubmed

Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin.

CYP3A7 CYP3A4

3.84e-053125220615193
Pubmed

Effects of hypoxia-inducible factor-1α chemical stabilizer, CoCl(2) and hypoxia on gene expression of CYP3As in human fetal liver cells.

CYP3A7 CYP3A4

3.84e-053125222277676
Pubmed

Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9.

DNM3 DNM1

3.84e-053125235065714
Pubmed

Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies.

CYP3A7 CYP3A4

3.84e-053125232001245
Pubmed

Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies.

BCL6 BCOR

3.84e-053125228827447
Pubmed

The Eps15 C. elegans homologue EHS-1 is implicated in synaptic vesicle recycling.

DNM1 DNM2

3.84e-053125211483962
Pubmed

CYP3A Polymorphism and Chronic Mercury Intoxication.

CYP3A7 CYP3A4

3.84e-053125232146629
Pubmed

Genetic interaction between Scn8a and potassium channel genes Kcna1 and Kcnq2.

KCNA1 SCN8A

3.84e-053125235892317
Pubmed

Differences in CYP3A41G genotype distribution and haplotypes of CYP3A4, CYP3A5 and CYP3A7 in 3 Chinese populations.

CYP3A7 CYP3A4

3.84e-053125217582393
Pubmed

The ARID family transcription factor bright is required for both hematopoietic stem cell and B lineage development.

ARID3A ARID3B

3.84e-053125221199920
Pubmed

CYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in recipients rather than donors influence tacrolimus concentrations in the early stages after liver transplantation.

CYP3A7 CYP3A4

3.84e-053125234688813
Pubmed

Molecular genetics of the human cytochrome P450 monooxygenase superfamily.

CYP3A7 CYP2E1 CYP3A4

4.94e-052012539890157
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CUL4B ARHGAP23 AOX1 LAMB1 CHD9 BCOR ARID1B TAF3 TYW5 PANK4 CHPF2 TOP1 AGTPBP1 KNL1

5.07e-0511161251431753913
GeneFamilyAT-rich interaction domain containing

ARID3A ARID3B ARID1B

4.38e-0515853418
GeneFamilyCytochrome P450 family 3

CYP3A7 CYP3A4

6.00e-0488521002
CoexpressionGSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_UP

CYP3A7 NDUFAF5 AOX1 DYRK1A AKTIP SMTNL1 KLHL23 CORO6 ALDH1A3

4.68e-071991249M7766
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

CUL4B TCEAL3 SLF1 IQGAP2 PPIL4 PBK ECT2 TAOK3 FSTL1 ITSN2 CDC5L AGTPBP1 USP47 KNL1 RBM17

5.19e-0765612415M18979
CoexpressionMARTIN_INTERACT_WITH_HDAC

CAMK1 BCL6 BCOR ANKRD11 NKX2-5

1.43e-06411245M15154
CoexpressionGSE17301_CTRL_VS_48H_ACD3_ACD28_STIM_CD8_TCELL_UP

IQGAP2 NPEPPS BCL6 ARID3B MYO15B FSTL1 HOXD12 RNF216

5.16e-062001248M8045
CoexpressionGSE6259_CD4_TCELL_VS_CD8_TCELL_DN

IQGAP2 DYRK1A CHD9 TAOK3 ARID1B TAF3 PEAK1

2.83e-051841247M6739
CoexpressionGSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP

NDUFAF5 SLC2A9 PBX4 CHD9 POLI CHD6 PEAK1

4.80e-052001247M6004
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPEPPS BCL6 CMYA5 MYO5C RIMS1 ALDH1A3 PATJ

7.14e-0717912476e965e424eebef50f0202cff75f458be395cfca1
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT15 SMTNL1 ASMT DGKK C2orf92 ECEL1

3.71e-061481246dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCell367C-Fibroblasts-Fibroblast-F|367C / Donor, Lineage, Cell class and subclass (all cells)

NPR1 AOX1 PBK FSTL1 CORO6 LRRC17

7.18e-0616612462887f4f0c218cbcbcc82eef27aa4ee714b35cddb
ToppCell367C-Fibroblasts-Fibroblast-F-|367C / Donor, Lineage, Cell class and subclass (all cells)

NPR1 AOX1 PBK FSTL1 CORO6 LRRC17

7.18e-0616612461cc291a04f4144abba4aca7badeb7776db05d903
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)|Striatum / BrainAtlas - Mouse McCarroll V32

SLF1 PPIL4 DYRK1A TRMT13 COG5 HECA

7.95e-061691246c3bf0cb67f200d02d5a021754e9b2a68d23ea168
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)--|Striatum / BrainAtlas - Mouse McCarroll V32

SLF1 PPIL4 DYRK1A TRMT13 COG5 HECA

7.95e-0616912465375eb52ebadccb7bfff997a11985f23e81014d6
ToppCellIonocyte-iono-1|World / Class top

NPR1 STAC3 CAMK1 SUPT6H PEAK1 ALDH1A3

7.95e-0616912464b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)-|Striatum / BrainAtlas - Mouse McCarroll V32

SLF1 PPIL4 DYRK1A TRMT13 COG5 HECA

7.95e-0616912461c132d21255f5a5174ac38db4e91927f9093418e
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAXO2 CMYA5 PABIR2 NKX2-5 PATJ ENO3

8.23e-061701246d99f61aa85ea3f775165cb433421e6f1cda4f96b
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAXO2 CMYA5 PABIR2 NKX2-5 PATJ ENO3

8.23e-061701246615cf9639c66b3fbd984ebe3f345280005d3c38a
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPR1 POLR3C SYT15 SMTNL1 POLI MPPE1

9.09e-0617312464968712af1cca8c932abd3323631d7dcaffd4a66
ToppCelldroplet-Spleen-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP23 POLA1 PBK ASMT KLHL23 KNL1

1.46e-0518812461a3f95b4fd7611c634666761ddf21f1e58e56af8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 BCL6 CLSTN1 TMEM171 DNM3 PATJ

1.55e-0519012461cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PBK ECT2 MYO5C MYO3A MPP7 KNL1

1.59e-05191124639220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

ARID3A F5 SCN8A CHD6 PATJ SDK1

1.69e-051931246503a979328c68b096680b71359a26f02fafdff35
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

AOX1 FSTL1 CORO6 ALDH1A3 SDK1 RAI2

1.69e-051931246261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellStriatum-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Dkk3_(Deep_layer_cortex)-|Striatum / BrainAtlas - Mouse McCarroll V32

DNAH2 MYO5C RAD51AP2 RANBP3L SDK1

1.69e-0511412453352ce794a646e3e7f15a991dd8a847a3c705394
ToppCellStriatum-Neuronal-Excitatory-eN1(Slc17a7)|Striatum / BrainAtlas - Mouse McCarroll V32

DNAH2 MYO5C RAD51AP2 RANBP3L SDK1

1.69e-051141245158dc333b337d5e83183b2f010a8e030c7a57bc7
ToppCellStriatum-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Slc17a7.Dkk3_(Deep_layer_cortex)|Striatum / BrainAtlas - Mouse McCarroll V32

DNAH2 MYO5C RAD51AP2 RANBP3L SDK1

1.69e-051141245238f2541e0514df8d24d767f833980d770b920a4
ToppCellStriatum-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Striatum / BrainAtlas - Mouse McCarroll V32

DNAH2 MYO5C RAD51AP2 RANBP3L SDK1

1.69e-051141245e63c0ebf843392c2926732bb8792eb6ee69bec15
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_mature|E16.5-samps / Age Group, Lineage, Cell class and subclass

CDH23 SAXO2 CMYA5 CORO6 ALDH1A3

1.77e-051151245c3f6efb90d5ee01af831f65e240505faa6a71dc0
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RSPH4A DNAH2 SAXO2 STOX1 DYNC2LI1 WDR49

1.85e-05196124627b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellmLN-B_cell-B_cell_cycling|mLN / Region, Cell class and subclass

CASC3 STAC3 BCL6 ECT2 NKX6-3 ALDH1A3

1.90e-051971246806dddcca85c82bd642008d930c8db16b613d88e
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NPR1 AOX1 LAMB1 FSTL1 ALDH1A3 RAI2

1.90e-0519712463bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCellmLN-B_cell-B_cell_cycling|B_cell / Region, Cell class and subclass

CASC3 STAC3 BCL6 ECT2 NKX6-3 ALDH1A3

1.90e-0519712462071526fe46de8359ea118ff78581eb4454aa55a
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NPR1 AOX1 LAMB1 FSTL1 ALDH1A3 RAI2

1.90e-05197124617344464fdcc5ba0c03959696b97c195f11e644c
ToppCellmLN-(2)_B_cell-(24)_B_cell_cycling|mLN / shred on region, Cell_type, and subtype

CASC3 STAC3 BCL6 ECT2 NKX6-3 ALDH1A3

1.90e-05197124670fff2d6723f259e18e7a21d22dc46d71f0759ce
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NPR1 AOX1 LAMB1 FSTL1 ALDH1A3 RAI2

1.90e-0519712465b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RSPH4A DNAH2 SAXO2 STOX1 DYNC2LI1 WDR49

1.95e-051981246ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLF1 GRIA3 SCN8A CORO6 RIMS1 DNM1

1.95e-0519812464ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQGAP2 FSTL1 PJA1 ALDH1A3 RAI2 LRRC17

2.01e-051991246a697b3f0760e66bad8ea8d83cf6fea5934692c56
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

AOX1 LAMB1 BCL6 FSTL1 ALDH1A3 SDK1

2.01e-0519912468b86c69aaf60feff53aa782559cfece7342a23de
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-BMP_responsible_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

CDH23 F5 MYO5C GMNC FSTL1 ECEL1

2.07e-0520012468433f4d3e26f6706bc7f06597d10b89221ce6437
ToppCell(09)_Ionocytes-(4)_1wkpi|(09)_Ionocytes / shred by cell type and Timepoint

AKTIP POLI RNF216

3.03e-05221243b35fb230042a027b10ef3e7ef09bf13ea1cdc506
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GMNC RAD51AP2 RIMS1 ALDH1A3 SDK1

8.30e-05159124560b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7|Thalamus / BrainAtlas - Mouse McCarroll V32

NPR1 PBX4 SYT15 TMEM131L ENO3

8.55e-0516012457d34159363d274019e14549d1186c629ce990691
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2|Thalamus / BrainAtlas - Mouse McCarroll V32

NPR1 PBX4 SYT15 TMEM131L ENO3

8.55e-051601245fe5fb0e7a79862f63529721f0a82f4f6d231d3ca
ToppCell367C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NPR1 PBK MYO3A RIMS1 KNL1

8.81e-051611245c61283c301a87bb802f6f8ce79c26067032dd7d9
ToppCell367C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NPR1 PBK MYO3A RIMS1 KNL1

8.81e-0516112459864d8b0929dacf4be7a4e97d2527ac3120ea264
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARID3A CDH23 ARID3B ARID1B DNM3

9.33e-0516312457a04192710f55acf5a4681d5f09942358fdb02ff
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PBK CLSTN1 ECT2 SCN8A KNL1

9.89e-05165124596f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-7|TCGA-Kidney / Sample_Type by Project: Shred V9

RSPH4A LAMB1 DYNC2LI1 CORO6 DNM1

1.02e-041661245b545de32578047c9ca422354b8992f2d9c9e1cc7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 ARHGAP23 CMYA5 F5 WDR49

1.08e-041681245fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 ARHGAP23 CMYA5 F5 WDR49

1.08e-041681245315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 ARHGAP23 CMYA5 F5 WDR49

1.08e-041681245e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IQGAP2 PBK PBX4 ECT2 KNL1

1.14e-041701245b04e2f84024baaae9b4ff19bdac8c69afdb92a76
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

NPR1 MYO3A FSTL1 DNM1 SDK1

1.20e-04172124536a96714a0eb6ac438648135336c9791881ddadb
ToppCellBasal_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FSTL1 ALDH1A3 DNM1 WDR49 SDK1

1.27e-041741245a0060be3940043015dcc49a5157de5541aed24a1
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CAMK1 BCL6 MILR1 TMEM131L USP6NL

1.27e-041741245fde40c5d51f5380088360dc5a583eb04e518deb6
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CAMK1 FSTL1 RANBP3L ENO3 WDR49

1.30e-0417512452dcb5145835c3872d0f92f3ece23730cf65487bd
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRIA3 MYO3A TMEM131L CORO6 SDK1

1.30e-041751245d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCell10x_5'_v1-Neoplastic-Differentiated-like|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CAMK1 FSTL1 RANBP3L ENO3 WDR49

1.30e-0417512453c3cbaeec6ef2f61e6b177c95b999752c2d83ddb
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRIA3 MYO3A TMEM131L CORO6 SDK1

1.30e-041751245454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO5C RIMS1 PATJ WDR49 SDK1

1.34e-0417612453bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NPR1 LAMB1 MYO3A ALDH1A3 RAI2

1.37e-0417712453d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TCEAL3 KLHL23 RIMS1 GRIN3A ENO3

1.37e-041771245c9b02a2e1ff2aa18c37e88a53b06a5b696a442ae
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PBK ECT2 MYO5C TMEM171 KNL1

1.37e-041771245a68c3688f12aee22f3cb4049c4bccacbacb0fae6
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

TAF3 DNM3 MLLT6 USP47 RBM17

1.37e-041771245e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RSPH4A DNAH2 SAXO2 WDR49 SDK1

1.45e-0417912455e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPR1 CDK19 SYT15 NKX6-3 FSTL1

1.52e-0418112454d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 CLSTN1 KCNA1 ALDH1A3 PATJ

1.56e-0418212456fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCelldroplet-Lung-nan-21m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEAL3 CYP2E1 FSTL1 DNM3 RAI2

1.60e-041831245b153425ab0df1e5fa9b953e1f6d4e8e3dc6621b0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NPR1 IQGAP2 ARHGAP23 F5 WDR49

1.60e-041831245848fc6dd129150897ee339343e83c645b6e779eb
ToppCelldroplet-Lung-nan-21m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEAL3 CYP2E1 FSTL1 DNM3 RAI2

1.60e-04183124519e7be1cfdd111bfb840532a6f7c780345dffccf
ToppCellfacs-Heart-RA-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMYA5 SYDE2 NKX2-5 CORO6 ENO3

1.65e-04184124572b42dfca7e9c0257f11d8242531e843271871a7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NPR1 BCL6 DYNC2LI1 DNM3 ALDH1A3

1.65e-041841245da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellfacs-Heart-RA-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMYA5 SYDE2 NKX2-5 CORO6 ENO3

1.65e-041841245c6f4537ae8b6e8fde1be17df14629b7b49b4997c
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

SLF1 CHD9 KLHL23 CHD6 PJA1

1.69e-041851245857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 ARHGAP23 CMYA5 F5 WDR49

1.69e-0418512459197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 ARHGAP23 CMYA5 F5 WDR49

1.69e-041851245ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPR1 IQGAP2 ARHGAP23 F5 WDR49

1.69e-041851245b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

HOXD12 RIMS1 ALDH1A3 PATJ SDK1

1.73e-041861245d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|356C / Donor, Lineage, Cell class and subclass (all cells)

PBK ECT2 MYO5C MYO3A KLHL23

1.73e-041861245189b75aa98903f1cb65b624524ba6c30df7e42ff
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RSPH4A DNAH2 SAXO2 STOX1 WDR49

1.73e-04186124576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 PBX4 PPP2R5C TMEM131L MPP7

1.73e-0418612459d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|356C / Donor, Lineage, Cell class and subclass (all cells)

PBK ECT2 MYO5C MYO3A KLHL23

1.73e-041861245261891d0b148e285339ae0b9e36136ceabd9b6f5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 LAMB1 DNM1 PATJ SDK1

1.73e-041861245b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RSPH4A DNAH2 SAXO2 STOX1 WDR49

1.77e-0418712459e10ed56090d82589bc457788282f664b70ace4b
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

NPEPPS DYRK1A ARID1B ANKRD11 TMEM131L

1.82e-041881245ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CYTH1 PBX4 PPP2R5C TMEM131L

1.86e-041891245b87d586a9570fa54f3e0c6bd4731c5badcaedae6
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AOX1 LAMB1 FSTL1 ALDH1A3 SDK1

1.86e-041891245e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NPR1 FSTL1 ALDH1A3 SDK1 LRRC17

1.86e-041891245c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

LAMB1 ARID1B RANBP3L DNM3 PATJ

1.86e-041891245830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CYTH1 PBX4 PPP2R5C TMEM131L

1.86e-041891245823d6debd09e440ddf36c54af24a5f20e222a21e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IQGAP2 CYTH1 PBX4 PPP2R5C TMEM131L

1.86e-04189124547c2b419b081d5bf75da5e3d9a0e05a70362dfe7
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEAL3 CYP2E1 CMYA5 KLHL23 RIMS1

1.86e-0418912454dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 GRIA3 MYO3A DNM1 SDK1

1.86e-04189124528b502611829e4a24caff2562545c7db97686099
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEAL3 CYP2E1 CMYA5 KLHL23 RIMS1

1.86e-0418912450d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

SLC2A9 AOX1 DNM1 PATJ SDK1

1.86e-0418912450be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellCiliated|World / shred by cell class for parenchyma

RSPH4A DNAH2 SAXO2 STOX1 WDR49

1.86e-041891245711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AOX1 LAMB1 FSTL1 ALDH1A3 SDK1

1.91e-04190124545df8fee00f8949937863159d7aa042e72748d9b
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 POLA1 PBK ECT2 KNL1

1.91e-041901245b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NPR1 LAMB1 FSTL1 ALDH1A3 DNM1

2.01e-04192124530cefa0990ba1f379f350bfbf994a78db145075e
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AOX1 LAMB1 FSTL1 ALDH1A3 SDK1

2.01e-041921245f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AOX1 LAMB1 FSTL1 ALDH1A3 SDK1

2.01e-0419212454e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

AOX1 FSTL1 ALDH1A3 DNM1 LRRC17

2.01e-041921245a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 ARID1B ANKRD11 PATJ SDK1

2.01e-041921245e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH2 STOX1 KCNA1 WDR49 SDK1

2.05e-041931245ea345d34440b25f65358a53dc72831998d1c3620
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPR1 LAMB1 BCL6 DYNC2LI1 ALDH1A3

2.05e-0419312450f2167eef8203a5659c8c72e4e77646003d64797
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLF1 POLA1 LAMB1 FSTL1 KLHL23

2.05e-041931245f25bdd10ef531b8d8441ea84573078b4b1b0f105
ComputationalCytochrome P450.

CYP3A7 CYP2E1 CYP3A4

1.12e-0414753MODULE_106
Diseasecentronuclear myopathy 1 (implicated_via_orthology)

DNM3 DNM1 DNM2

6.36e-0751193DOID:0111223 (implicated_via_orthology)
Diseasemicrocytic anemia (implicated_via_orthology)

DNM3 DNM1 DNM2

6.36e-0751193DOID:11252 (implicated_via_orthology)
DiseaseCharcot-Marie-Tooth disease dominant intermediate B (implicated_via_orthology)

DNM3 DNM1 DNM2

6.36e-0751193DOID:0110197 (implicated_via_orthology)
DiseaseNeurodevelopmental Disorders

DYRK1A ARID1B SCN8A ANKRD11 RIMS1 DNM1

2.17e-06931196C1535926
Diseasecollagen disease (implicated_via_orthology)

DNM3 DNM1 DNM2

1.37e-05121193DOID:854 (implicated_via_orthology)
Diseasedevelopmental and epileptic encephalopathy (implicated_via_orthology)

DNM3 DNM1 DNM2

1.78e-05131193DOID:0112202 (implicated_via_orthology)
DiseaseEpilepsy, Cryptogenic

DYRK1A ARID1B SCN8A ANKRD11 DNM1

2.09e-05821195C0086237
DiseaseAwakening Epilepsy

DYRK1A ARID1B SCN8A ANKRD11 DNM1

2.09e-05821195C0751111
DiseaseAura

DYRK1A ARID1B SCN8A ANKRD11 DNM1

2.09e-05821195C0236018
Diseasehereditary spastic paraplegia (implicated_via_orthology)

RTN4 DNM3 DNM1 DNM2

2.75e-05431194DOID:2476 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

DYRK1A CHD9 TAOK3 ARID1B CHD6 RIMS1

3.64e-051521196DOID:0060041 (implicated_via_orthology)
Diseaselymphocyte count

CYP3A7 IQGAP2 PCDHGB2 CYP3A4 RTN4 CDH23 PBX4 PSMD3 CLSTN1 ERLEC1 TMEM171 ERCC6L2 ANKRD11 NKX2-5 CDC5L KNL1 RBM17

8.19e-05146411917EFO_0004587
DiseaseEpilepsy

DYRK1A ARID1B SCN8A ANKRD11 DNM1

8.20e-051091195C0014544
Diseasetacrolimus measurement

CYP3A7 CYP3A4

9.63e-0541192EFO_0008458
Diseaseestrone conjugate measurement

CYP3A7 CYP3A4

9.63e-0541192EFO_0007971
Diseasetauro-beta-muricholate measurement

CYP3A7 CYP3A4

1.60e-0451192EFO_0800213
Diseaseglyco-beta-muricholate measurement

CYP3A7 CYP3A4

1.60e-0451192EFO_0800569
Diseasedehydroisoandrosterone sulfate DHEA-S measurement

CYP3A7 CYP3A4

2.39e-0461192EFO_0021119
Diseaseandrostenediol (3beta,17beta) monosulfate (1) measurement

CYP3A7 CYP3A4

2.39e-0461192EFO_0800294
DiseaseCHARGE syndrome (implicated_via_orthology)

CHD9 CHD6

3.34e-0471192DOID:0050834 (implicated_via_orthology)
DiseaseX-24574 measurement

CYP3A7 CYP3A4

3.34e-0471192EFO_0800897
Diseasereaction time measurement

IQGAP2 ARHGAP23 CDK19 EFR3A ITSN2 POLI CHD6 RIMS1 GRIN3A DNM2

3.42e-0465811910EFO_0008393
DiseasePARTINGTON X-LINKED MENTAL RETARDATION SYNDROME

POLA1 GRIA3

4.44e-0481192C0796250
Diseaseandrostenediol (3beta,17beta) disulfate (1) measurement

CYP3A7 CYP3A4

5.70e-0491192EFO_0800278
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

CYP3A7 CYP3A4

7.11e-04101192EFO_0022090
Disease5alpha-androstan-3beta,17alpha-diol disulfate measurement

CYP3A7 CYP3A4

7.11e-04101192EFO_0800289
DiseaseDNA repair protein RAD51 homolog 4 measurement

CYP3A7 CYP3A4

8.66e-04111192EFO_0801531
Diseaseandrostenediol (3beta,17beta) monosulfate (2) measurement

CYP3A7 CYP3A4

8.66e-04111192EFO_0800295
Diseasemean platelet volume

IQGAP2 PCDHGB2 POLA1 NPEPPS DYRK1A CHD9 BCOR TMEM171 ANKRD11 DNM3 TMEM131L WDR49

8.71e-04102011912EFO_0004584
Diseaseocular hypertension, response to triamcinolone acetonide

SLC2A9 CDH23 CHD9

1.03e-03491193EFO_0006954, EFO_1001069
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

CYP3A7 CYP3A4

1.04e-03121192EFO_0800291
DiseaseADHD symptom measurement

PBX4 ACTR3B

1.04e-03121192EFO_0007860
Diseaseobsolete_red blood cell distribution width

SAMD9 ARHGAP23 CYTH1 RTN4 CDH23 PBX4 ECT2 TMEM171 TAOK3 COG5 ENO3 USP47 DNM2 KNL1

1.08e-03134711914EFO_0005192
Diseaseputamen volume change measurement

TAF3 SYDE2

1.22e-03131192EFO_0021495
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

CYP3A7 CYP3A4

1.22e-03131192EFO_0800293
Disease5alpha-pregnan-3beta,20beta-diol monosulfate (1) measurement

CYP3A7 CYP3A4

1.22e-03131192EFO_0800284
DiseaseX-21470 measurement

CYP3A7 CYP3A4

1.42e-03141192EFO_0800817
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

CYP3A7 CYP3A4

1.42e-03141192EFO_0800283
Diseaseglucose homeostasis measurement, glucose effectiveness measurement

BCL6 MYO5C

1.64e-03151192EFO_0006833, EFO_0006896
Disease16a-hydroxy DHEA 3-sulfate measurement

CYP3A7 CYP3A4

1.64e-03151192EFO_0800301
DiseaseX-21410 measurement

CYP3A7 CYP3A4

1.87e-03161192EFO_0800813
Diseasecentral nervous system disease (implicated_via_orthology)

GRIA3 TAOK3

1.87e-03161192DOID:331 (implicated_via_orthology)
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

KCNA1 DNM1

1.87e-03161192C0393706
Diseaseandro steroid monosulfate C19H28O6S (1) measurement

CYP3A7 CYP3A4

1.87e-03161192EFO_0800305
DiseaseAlzheimer disease, psychotic symptoms

SLC2A9 MPP7

2.11e-03171192EFO_0005940, MONDO_0004975
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

CYP3A7 CYP3A4

2.37e-03181192EFO_0800288
Diseasemetabolonic lactone sulfate measurement

CYP3A7 CYP3A4

2.64e-03191192EFO_0800659
Diseaseetiocholanolone glucuronide measurement

CYP3A7 CYP3A4

2.64e-03191192EFO_0800362
Diseasecongenital heart disease (implicated_via_orthology)

CHD9 NKX2-5 CHD6

2.76e-03691193DOID:1682 (implicated_via_orthology)
Diseaseandrosterone glucuronide measurement

CYP3A7 CYP3A4

2.92e-03201192EFO_0800317
Diseasethyroid peroxidase antibody measurement

ERCC6L2 TMEM131L RBM17

3.11e-03721193EFO_0005666
DiseaseLymphoma, Diffuse

CYP2E1 BCL6

3.22e-03211192C3714542
DiseaseLow Grade Lymphoma (neoplasm)

CYP2E1 BCL6

3.22e-03211192C0079747
DiseaseLymphoma, Intermediate-Grade

CYP2E1 BCL6

3.22e-03211192C0079741
DiseaseHigh Grade Lymphoma (neoplasm)

CYP2E1 BCL6

3.22e-03211192C0079740
DiseaseDiffuse Mixed-Cell Lymphoma

CYP2E1 BCL6

3.22e-03211192C0079757
Diseasesystemising measurement

CLSTN1 ERLEC1

3.22e-03211192EFO_0010221
DiseaseLymphoma, Undifferentiated

CYP2E1 BCL6

3.22e-03211192C0024306
DiseaseReticulosarcoma

CYP2E1 BCL6

3.22e-03211192C0024302
DiseaseLymphoma, Mixed-Cell

CYP2E1 BCL6

3.22e-03211192C0024304
Diseaseintellectual disability (implicated_via_orthology)

CUL4B DYRK1A ITSN2

3.50e-03751193DOID:1059 (implicated_via_orthology)
DiseaseX-24947 measurement

CYP3A7 CYP3A4

3.53e-03221192EFO_0800910
Disease5alpha-androstan-3beta,17beta-diol disulfate measurement

CYP3A7 CYP3A4

3.53e-03221192EFO_0021115
DiseaseLymphoma, Non-Hodgkin, Familial

CYP2E1 BCL6

3.53e-03221192C4721532
DiseaseLymphoma, Small Noncleaved-Cell

CYP2E1 BCL6

3.53e-03221192C0079770

Protein segments in the cluster

PeptideGeneStartEntry
FAKLYELDGDPERKE

ARID3B

206

Q8IVW6
EEKDYKGPNPRELLE

ERLEC1

91

Q96DZ1
SAFPKLEQPEEDKYS

MLLT6

356

P55198
RGVDYNAEIPFEKKP

CDC5L

206

Q99459
PQKATAPVKDEYEFD

ANKRD11

336

Q6UB99
IPYPKREFLNEDDPE

CDK19

351

Q9BWU1
PDIVKEFAKYDVDPR

ACTR3B

236

Q9P1U1
TARLFDQPKIEDPYA

AKTIP

221

Q9H8T0
EYAKKRPVGDPFDVK

ALDH1A3

336

P47895
ESPDFQPNIAKKYID

PPP2R5C

146

Q13362
PERKRAPQTYEKEED

ARID1B

2056

Q8NFD5
DFFKDPLPEADLYIL

ASMT

236

P46597
FRQDPSEEKKYRPAE

CLSTN1

431

O94985
DQAPKARKFFEKLPD

DYRK1A

386

Q13627
DPDNPEYLEFLKQLK

NPR1

316

P16066
PFEAPEDKDLPVEKY

BCOR

1091

Q6W2J9
DYDLSPAKQEPKPFD

BCOR

1406

Q6W2J9
DDFQDYDLISKEPKP

AGTPBP1

431

Q9UPW5
EPAAVKPDDDRYLRA

CDH23

3176

Q9H251
YKRLVDNIFPEDPKD

EFR3A

16

Q14156
SFKPERKLEYGNVDE

AOX1

716

Q06278
RPAFLPDECKEEFNY

RAD51AP2

1091

Q09MP3
DELKPFDILQPKEYF

RAI2

286

Q9Y5P3
ELYNEFPEPIKLDKN

RAB7A

181

P51149
VLYDNQEFPDPEKFK

CYP2E1

396

P05181
YAAVDDFRNEFKVPP

ECT2

256

Q9H8V3
REEPEALYAAVNKKP

ITSN2

961

Q9NZM3
FKEYEKEQDKPPNLV

PPIL4

336

Q8WUA2
ENRPKYPGIKFEELF

MAPK9

261

P45984
EYADSSKADRKPFIP

DGKK

736

Q5KSL6
FIKEEERPLPEKEYQ

KCNA1

136

Q09470
LYANPREPEKSLKFD

MGAM2

1356

Q2M2H8
SFGRPVDLEKDDYQK

HECA

101

Q9UBI9
VEEYKNFRPDDPARK

DNM1

311

Q05193
PKDKLPAYPESFDQD

LRRC17

401

Q8N6Y2
KDIKDPARDPQYAEN

DYNC2LI1

306

Q8TCX1
PERFSKKNKDNIDPY

CYP3A4

416

P08684
VEAYKNFKPEDPTRK

DNM3

311

Q9UQ16
APAEERDIPFKENYD

MPPE1

266

Q53F39
DEREFPEAKNAPLKY

GRIA3

291

P42263
EYFDLAEKQTPDGRK

PCDHGB2

176

Q9Y5G2
PNPFDENPELKEREY

PEAK1

1606

Q9H792
LFDYNPNEDKAIPCK

MPP7

236

Q5T2T1
YESIKNEPFKIPEDD

CYTH1

236

Q15438
IFRALDPAFKIEDPY

LAMB1

206

P07942
DKENFEIPIYSKEPN

KNL1

261

Q8NG31
EYDFPEKFFPKARDL

PDPK2P

271

Q6A1A2
RKPYPDDENLVEVKF

NPEPPSL1

221

A6NEC2
VEEYKNFRPDDPTRK

DNM2

311

P50570
AYSDPDPAKDPRAEK

NKX2-5

96

P52952
EKNYAFEIPDVPEKS

POLA1

436

P09884
GYPDFLLKPDAVDKE

ECEL1

511

O95672
FNLTKKNPGEEEEYR

MILR1

181

Q7Z6M3
PDGVEYLKNDPEKLD

GRIN3A

826

Q8TCU5
DFDKPEKLYSPKRID

PABIR2

96

Q7Z309
DPYFGFEEAKRKLQE

PANK4

581

Q9NVE7
DYPDTPEKRDEGKAA

RIMS1

326

Q86UR5
PPFYDENDAKLFEQI

CAMK1

216

Q14012
EAEDRPYQPKSFQQK

MYO15B

956

Q96JP2
PYPSEEAKEELARKG

PBX4

236

Q9BYU1
DAQDIFIPKKPDYDP

COG5

456

Q9UP83
SKEPYPDFVARLQDA

ERVK-5

446

Q9HDB9
EYKPAPAIFKDDIED

CHD9

1736

Q3L8U1
APAEEAEFYDPLKEK

KLHL23

381

Q8NBE8
PEYFLGSVDKIPDKD

C2orf92

121

A0A1B0GVN3
DDDEDRKNPAYIPRK

CASC3

171

O15234
ENDEFEIEKPKAYIP

CHD6

1951

Q8TD26
EFLEEPPALAFLYKD

CMYA5

3181

Q8N3K9
FNPPEKKCALEDETY

FSTL1

226

Q12841
KDGPEEQAKFYAPEA

HOXD12

91

P35452
VPRKSDLFQDDLYPD

CORO6

351

Q6QEF8
APYFPCDKASKEEER

BCL6

291

P41182
DANPRYKIPVEADFL

CASP7

206

P55210
KRNKAYPPEEKIDSA

SLC2A9

516

Q9NRM0
DFYRKNDIPSLKEPG

C5orf49

126

A4QMS7
KYDLDFKSPDDPARH

ENO3

256

P13929
PERFSKKNKDNIDPY

CYP3A7

416

P24462
DDEDLEKPYFPNRKF

ERCC6L2

96

Q5T890
PIFGDFLKEPKVYED

DNAH2

2691

Q9P225
EDFPKDKETNRDFLP

POLI

476

Q9UNA4
GYKILFRAKDLDPEP

SDK1

1311

Q7Z5N4
RKPYPDDENLVEVKF

NPEPPS

221

P55786
NFKDKPKLPENYTDE

CUL4B

201

Q13620
PAFKYQFVREPEDEE

RTN4

21

Q9NQC3
DEEDELPKSFYKAPQ

RSPH4A

401

Q5TD94
FYGAEDLKPPRIDSK

SYDE2

686

Q5VT97
QPGSKDAEERKEYIP

TAF3

111

Q5VWG9
SREKPKPDFYIQDIN

TRMT13

81

Q9NUP7
AINPELYKFPEDKSE

SYT15

126

Q9BQS2
DPLKPYQDFIIDSRE

TRNT1

341

Q96Q11
DAKNRGYLADPAKFP

MRPL15

216

Q9P015
KQDIPFVEQEDPYRK

TMEM131L

1181

A2VDJ0
FCENPDEVKRDDPKF

F5

566

P12259
FPDDAVDYKNIPRED

GMNC

226

A6NCL1
YNKPLDPDSDDEKIR

NKX6-3

231

A6NJ46
GRLDLDSEKYKPFDP

SAMD9

496

Q5K651
RKYFKEACNVPEPEE

IQGAP2

1176

Q13576
LKDPEIADLFYKDDP

TAOK3

6

Q9H2K8
FLLENPDYPKREDRI

RNF216

321

Q9NWF9
RQPEPTKFDYLKEEV

NDUFAF5

61

Q5TEU4
EEQFKQLYELDGDPK

ARID3A

226

Q99856
QLYELDGDPKRKEFL

ARID3A

231

Q99856
LDQSDEDFKPRIVPY

CHPF2

61

Q9P2E5
SKKSEAEFRDYPPVL

SUPT6H

896

Q7KZ85
RAKLDLPEPGKEDEY

USP6NL

351

Q92738
FPPKSYNKDLESAEE

PSMD3

496

O43242
DEDAAGEPKAKRPKY

POLR3C

206

Q9BUI4
FPDAFDYAELDPAKR

SMTNL1

421

A8MU46
APKGFRDEPYFKEEL

PATJ

811

Q8NI35
RDEPYFKEELVDEPF

PATJ

816

Q8NI35
RIFDGKAKEPYAEQP

STOX1

541

Q6ZVD7
RKLPEPLFTDDKYND

ARHGAP23

986

Q9P227
PQLENDSYAKEKPFK

RANBP3L

231

Q86VV4
LVEKDKELPRDFPYE

RBM17

181

Q96I25
NPELYKFPEDKSETD

SYT15B

181

X6R8R1
FLLDPEKYFRKEPEE

WDR49

631

Q8IV35
EKYFRKEPEEERPQI

WDR49

636

Q8IV35
PARNAKFLEVDEYPE

USP47

566

Q96K76
AAVDSRKPDEQPKYE

SCN8A

1421

Q9UQD0
LIEERYKASQDPFPA

PBK

126

Q96KB5
PPRYEEKENAAATFL

TMEM171

301

Q8WVE6
EKEKDNFKAPFYPIQ

SLF1

176

Q9BQI6
AAEKRPAEDYVPRKA

TCEAL3

96

Q969E4
RPKEVYKPTDQRFED

SAXO2

166

Q658L1
DNKKYAVDDVPFSIP

WDR12

11

Q9GZL7
YRFKALEKDDLDFPP

STAC3

256

Q96MF2
YPEDKREARSDQVKP

PJA1

321

Q8NG27
LKRPRDEDDADYKPK

TOP1

136

P11387
DNPDLAKYPLFSKAR

TYW5

201

A2RUC4
KEEEREPAANPYDFR

MYO3A

1586

Q8NEV4
YVRCIKPNDEKLPFE

MYO5C

646

Q9NQX4