Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRC PTPRG PTPRK PTPRN2 PTPRZ1 PTPRT	2.13e-11	17	72	6	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRC PTPRG PTPRK PTPRN2 PTPRZ1 PTPRT	2.13e-11	17	72	6	GO:0019198
GeneOntologyMolecularFunction	protein tyrosine phosphatase activity	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 TNS2 PTPRT	1.18e-10	103	72	9	GO:0004725
GeneOntologyMolecularFunction	phosphoprotein phosphatase activity	PTPRC PPP5C PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 TNS2 PTPRT	1.47e-09	189	72	10	GO:0004721
GeneOntologyMolecularFunction	phosphatase activity	PTPRC PPP5C PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 TNS2 PTPRT	7.87e-08	287	72	10	GO:0016791
GeneOntologyMolecularFunction	phosphoric ester hydrolase activity	PTPRC PPP5C PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 TNS2 PTPRT	1.20e-06	386	72	10	GO:0042578
GeneOntologyMolecularFunction	spectrin binding	PTPRC PTPRN USH1C DYNC1I1	6.64e-06	34	72	4	GO:0030507
GeneOntologyMolecularFunction	hydrolase activity, acting on ester bonds	PTPRC PPP5C PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 TNS2 HNF4A PTPRT	1.39e-04	807	72	11	GO:0016788
GeneOntologyMolecularFunction	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	GATB PFAS	5.66e-04	10	72	2	GO:0016884
GeneOntologyMolecularFunction	alpha-catenin binding	AJUBA PTPRT	8.27e-04	12	72	2	GO:0045294
GeneOntologyMolecularFunction	gamma-catenin binding	PTPRK PTPRT	8.27e-04	12	72	2	GO:0045295
GeneOntologyMolecularFunction	beta-catenin binding	PTPRK AR PTPRT AXIN1	9.31e-04	120	72	4	GO:0008013
GeneOntologyMolecularFunction	nuclear receptor activity	NR2C1 HNF4A AR	1.33e-03	60	72	3	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	NR2C1 HNF4A AR	1.39e-03	61	72	3	GO:0098531
GeneOntologyMolecularFunction	calcium ion binding	HSPG2 HMCN2 MGMT DSG2 ASAH2 LTBP3 F7 NOTCH1 NOTCH4	1.44e-03	749	72	9	GO:0005509
GeneOntologyMolecularFunction	peptidase activity	ADAM23 TMPRSS3 CELA1 USP9Y CTSB F7 CTSW ALG13	2.40e-03	654	72	8	GO:0008233
GeneOntologyMolecularFunction	growth factor binding	SRPX2 PTPRZ1 DUSP1 LTBP3	2.44e-03	156	72	4	GO:0019838
GeneOntologyMolecularFunction	Notch binding	NOTCH1 NOTCH4	4.25e-03	27	72	2	GO:0005112
GeneOntologyMolecularFunction	endopeptidase activity	ADAM23 TMPRSS3 CELA1 CTSB F7 CTSW	4.54e-03	430	72	6	GO:0004175
GeneOntologyBiologicalProcess	protein dephosphorylation	PTPRC PPP5C PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 TNS2 PTPRT	1.99e-08	256	72	10	GO:0006470
GeneOntologyBiologicalProcess	dephosphorylation	PTPRC PPP5C PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 TNS2 PTPRT	3.39e-07	347	72	10	GO:0016311
GeneOntologyBiologicalProcess	peptidyl-tyrosine dephosphorylation	PTPRZ1 DUSP1 TNS2 PTPRT	5.85e-06	34	72	4	GO:0035335
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	RGMA PTPRG PTPRK FGF5 TNS2 SHISA2 LTBP3 USP9Y F7 LRIT3 AR PTPRT NOTCH1 AXIN1	5.19e-05	1186	72	14	GO:0007167
GeneOntologyBiologicalProcess	positive regulation of aorta morphogenesis	NOTCH1 NOTCH4	7.18e-05	4	72	2	GO:1903849
GeneOntologyBiologicalProcess	regulation of phosphorylation	RGMA SRPX2 PTPRC PPP5C PTPRZ1 DUSP1 FGF5 MRNIP AJUBA HNF4A AR WDFY2 PTPRT AXIN1	7.42e-05	1226	72	14	GO:0042325
GeneOntologyCellularComponent	collagen-containing extracellular matrix	A1BG HSPG2 SRPX2 HMCN2 PTPRZ1 CELA1 LAMC3 LTBP3 CTSB F7	1.50e-05	530	73	10	GO:0062023
GeneOntologyCellularComponent	extracellular matrix	A1BG HSPG2 SRPX2 HMCN2 PTPRZ1 CELA1 LAMC3 LTBP3 CTSB F7	9.04e-05	656	73	10	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	A1BG HSPG2 SRPX2 HMCN2 PTPRZ1 CELA1 LAMC3 LTBP3 CTSB F7	9.27e-05	658	73	10	GO:0030312
GeneOntologyCellularComponent	cell surface	RGMA BTN3A3 SRPX2 PTPRC PTPRK DSG2 CD163L1 CTSB BTN3A2 PTPRT NOTCH1 NOTCH4	4.36e-04	1111	73	12	GO:0009986
Domain	PTPc_motif	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 PTPRT	6.19e-11	59	72	8	SM00404
Domain	Tyr_Pase_cat	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 PTPRT	6.19e-11	59	72	8	IPR003595
Domain	PTPc	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 PTPRT	7.16e-11	36	72	7	SM00194
Domain	-	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 TNS2 PTPRT	7.55e-11	92	72	9	3.90.190.10
Domain	TYR_PHOSPHATASE_PTP	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 PTPRT	1.31e-10	39	72	7	PS50055
Domain	Prot-tyrosine_phosphatase-like	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 TNS2 PTPRT	1.47e-10	99	72	9	IPR029021
Domain	PTPase_domain	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 PTPRT	1.90e-10	41	72	7	IPR000242
Domain	Y_phosphatase	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 PTPRT	1.90e-10	41	72	7	PF00102
Domain	Tyr_Pase_AS	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 PTPRT	3.60e-10	73	72	8	IPR016130
Domain	TYR_PHOSPHATASE_1	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 PTPRT	1.36e-09	86	72	8	PS00383
Domain	TYR_PHOSPHATASE_2	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 PTPRT	1.50e-09	87	72	8	PS50056
Domain	TYR_PHOSPHATASE_dom	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 PTPRT	1.50e-09	87	72	8	IPR000387
Domain	Ig-like_fold	A1BG HSPG2 BTN3A3 PTPRC HMCN2 PTPRG PTPRK PTPRZ1 OBSL1 GBE1 NCAM2 KIR2DS4 LRIT3 BTN3A2 PTPRT	6.17e-08	706	72	15	IPR013783
Domain	-	A1BG HSPG2 BTN3A3 PTPRC PTPRG PTPRK PTPRZ1 OBSL1 GBE1 NCAM2 KIR2DS4 LRIT3 BTN3A2 PTPRT	1.96e-07	663	72	14	2.60.40.10
Domain	FN3	PTPRC PTPRG PTPRK PTPRZ1 OBSL1 NCAM2 LRIT3 PTPRT	5.55e-07	185	72	8	SM00060
Domain	IG	A1BG HSPG2 BTN3A3 HMCN2 PTPRK OBSL1 NCAM2 KIR2DS4 LRIT3 BTN3A2 PTPRT	5.89e-07	421	72	11	SM00409
Domain	Ig_sub	A1BG HSPG2 BTN3A3 HMCN2 PTPRK OBSL1 NCAM2 KIR2DS4 LRIT3 BTN3A2 PTPRT	5.89e-07	421	72	11	IPR003599
Domain	FN3	PTPRC PTPRG PTPRK PTPRZ1 OBSL1 NCAM2 LRIT3 PTPRT	9.63e-07	199	72	8	PS50853
Domain	FN3_dom	PTPRC PTPRG PTPRK PTPRZ1 OBSL1 NCAM2 LRIT3 PTPRT	1.39e-06	209	72	8	IPR003961
Domain	IG_LIKE	A1BG HSPG2 BTN3A3 HMCN2 PTPRK OBSL1 NCAM2 KIR2DS4 LRIT3 BTN3A2 PTPRT	2.63e-06	491	72	11	PS50835
Domain	fn3	PTPRC PTPRG PTPRK PTPRZ1 OBSL1 NCAM2 PTPRT	2.98e-06	162	72	7	PF00041
Domain	Ig-like_dom	A1BG HSPG2 BTN3A3 HMCN2 PTPRK OBSL1 NCAM2 KIR2DS4 LRIT3 BTN3A2 PTPRT	3.32e-06	503	72	11	IPR007110
Domain	EGF-like_dom	HSPG2 HMCN2 ADAM23 LAMC3 LTBP3 F7 NOTCH1 NOTCH4	5.11e-06	249	72	8	IPR000742
Domain	EGF_1	HSPG2 HMCN2 ADAM23 LAMC3 LTBP3 F7 NOTCH1 NOTCH4	6.09e-06	255	72	8	PS00022
Domain	EGF-like_CS	HSPG2 HMCN2 ADAM23 LAMC3 LTBP3 F7 NOTCH1 NOTCH4	7.22e-06	261	72	8	IPR013032
Domain	EGF_CA	HSPG2 HMCN2 LTBP3 F7 NOTCH1 NOTCH4	7.54e-06	122	72	6	SM00179
Domain	EGF_2	HSPG2 HMCN2 ADAM23 LAMC3 LTBP3 F7 NOTCH1 NOTCH4	8.07e-06	265	72	8	PS01186
Domain	EGF-like_Ca-bd_dom	HSPG2 HMCN2 LTBP3 F7 NOTCH1 NOTCH4	8.28e-06	124	72	6	IPR001881
Domain	Receptor_IA-2	PTPRN PTPRN2	1.47e-05	2	72	2	PF11548
Domain	Receptor_IA-2_dom	PTPRN PTPRN2	1.47e-05	2	72	2	IPR021613
Domain	Growth_fac_rcpt_	HSPG2 HMCN2 LAMC3 LTBP3 NOTCH1 NOTCH4	3.06e-05	156	72	6	IPR009030
Domain	EGF_3	HSPG2 HMCN2 ADAM23 LTBP3 F7 NOTCH1 NOTCH4	3.36e-05	235	72	7	PS50026
Domain	EGF	HSPG2 ADAM23 LAMC3 LTBP3 F7 NOTCH1 NOTCH4	3.36e-05	235	72	7	SM00181
Domain	EGF_Ca-bd_CS	HMCN2 LTBP3 F7 NOTCH1 NOTCH4	3.62e-05	97	72	5	IPR018097
Domain	EGF_CA	HMCN2 LTBP3 F7 NOTCH1 NOTCH4	3.99e-05	99	72	5	PS01187
Domain	ASX_HYDROXYL	HMCN2 LTBP3 F7 NOTCH1 NOTCH4	4.19e-05	100	72	5	PS00010
Domain	RESP18	PTPRN PTPRN2	4.39e-05	3	72	2	PF14948
Domain	RESP18_dom	PTPRN PTPRN2	4.39e-05	3	72	2	IPR029403
Domain	EGF-type_Asp/Asn_hydroxyl_site	HMCN2 LTBP3 F7 NOTCH1 NOTCH4	5.54e-05	106	72	5	IPR000152
Domain	Notch	NOTCH1 NOTCH4	8.75e-05	4	72	2	IPR008297
Domain	NODP	NOTCH1 NOTCH4	8.75e-05	4	72	2	PF07684
Domain	Notch_NODP_dom	NOTCH1 NOTCH4	8.75e-05	4	72	2	IPR011656
Domain	Notch_NOD_dom	NOTCH1 NOTCH4	8.75e-05	4	72	2	IPR010660
Domain	NOD	NOTCH1 NOTCH4	8.75e-05	4	72	2	PF06816
Domain	NOD	NOTCH1 NOTCH4	8.75e-05	4	72	2	SM01338
Domain	NODP	NOTCH1 NOTCH4	8.75e-05	4	72	2	SM01339
Domain	Ig_I-set	HSPG2 HMCN2 PTPRK OBSL1 NCAM2 LRIT3	9.17e-05	190	72	6	IPR013098
Domain	ig	A1BG HSPG2 PTPRK OBSL1 NCAM2 KIR2DS4	9.17e-05	190	72	6	PF00047
Domain	Immunoglobulin	A1BG HSPG2 PTPRK OBSL1 NCAM2 KIR2DS4	9.17e-05	190	72	6	IPR013151
Domain	I-set	HSPG2 HMCN2 PTPRK OBSL1 NCAM2 LRIT3	9.17e-05	190	72	6	PF07679
Domain	LNR	NOTCH1 NOTCH4	1.45e-04	5	72	2	PS50258
Domain	hEGF	LTBP3 NOTCH1 NOTCH4	1.68e-04	28	72	3	PF12661
Domain	IGv	HSPG2 BTN3A3 NCAM2 BTN3A2	2.01e-04	75	72	4	SM00406
Domain	IGc2	A1BG HSPG2 HMCN2 OBSL1 NCAM2 LRIT3	2.91e-04	235	72	6	SM00408
Domain	Ig_sub2	A1BG HSPG2 HMCN2 OBSL1 NCAM2 LRIT3	2.91e-04	235	72	6	IPR003598
Domain	Notch_dom	NOTCH1 NOTCH4	3.04e-04	7	72	2	IPR000800
Domain	Notch	NOTCH1 NOTCH4	3.04e-04	7	72	2	PF00066
Domain	NL	NOTCH1 NOTCH4	3.04e-04	7	72	2	SM00004
Domain	EGF_CA	HMCN2 LTBP3 NOTCH1 NOTCH4	3.40e-04	86	72	4	PF07645
Domain	LAMININ_IVA	HSPG2 LAMC3	4.04e-04	8	72	2	PS51115
Domain	Laminin_B	HSPG2 LAMC3	4.04e-04	8	72	2	PF00052
Domain	LamB	HSPG2 LAMC3	4.04e-04	8	72	2	SM00281
Domain	Laminin_IV	HSPG2 LAMC3	4.04e-04	8	72	2	IPR000034
Domain	Pept_asp_AS	CTSB CTSW	6.46e-04	10	72	2	IPR025661
Domain	zf-C4	NR2C1 HNF4A AR	7.40e-04	46	72	3	PF00105
Domain	Znf_hrmn_rcpt	NR2C1 HNF4A AR	7.40e-04	46	72	3	IPR001628
Domain	NUCLEAR_REC_DBD_2	NR2C1 HNF4A AR	7.40e-04	46	72	3	PS51030
Domain	NUCLEAR_REC_DBD_1	NR2C1 HNF4A AR	7.40e-04	46	72	3	PS00031
Domain	ZnF_C4	NR2C1 HNF4A AR	7.40e-04	46	72	3	SM00399
Domain	Pept_his_AS	CTSB CTSW	7.88e-04	11	72	2	IPR025660
Domain	-	NR2C1 HNF4A AR	7.89e-04	47	72	3	1.10.565.10
Domain	HOLI	NR2C1 HNF4A AR	8.39e-04	48	72	3	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	NR2C1 HNF4A AR	8.39e-04	48	72	3	IPR000536
Domain	Hormone_recep	NR2C1 HNF4A AR	8.39e-04	48	72	3	PF00104
Domain	Pept_C1	CTSB CTSW	1.11e-03	13	72	2	SM00645
Domain	Peptidase_C1A_C	CTSB CTSW	1.11e-03	13	72	2	IPR000668
Domain	Peptidase_C1	CTSB CTSW	1.11e-03	13	72	2	PF00112
Domain	Peptidase_C1A	CTSB CTSW	1.11e-03	13	72	2	IPR013128
Domain	-	NR2C1 HNF4A AR	1.38e-03	57	72	3	3.30.50.10
Domain	EGF	HSPG2 F7 NOTCH1 NOTCH4	1.43e-03	126	72	4	PF00008
Domain	Znf_NHR/GATA	NR2C1 HNF4A AR	1.46e-03	58	72	3	IPR013088
Domain	MAM_1	PTPRK PTPRT	1.70e-03	16	72	2	PS00740
Domain	ALPHA_CA_2	PTPRG PTPRZ1	1.92e-03	17	72	2	PS51144
Domain	Carb_anhydrase	PTPRG PTPRZ1	1.92e-03	17	72	2	PF00194
Domain	Carb_anhydrase	PTPRG PTPRZ1	1.92e-03	17	72	2	SM01057
Domain	-	PTPRG PTPRZ1	1.92e-03	17	72	2	3.10.200.10
Domain	Carbonic_anhydrase_a	PTPRG PTPRZ1	1.92e-03	17	72	2	IPR001148
Domain	MAM	PTPRK PTPRT	1.92e-03	17	72	2	SM00137
Domain	MAM	PTPRK PTPRT	2.15e-03	18	72	2	PF00629
Domain	MAM_dom	PTPRK PTPRT	2.15e-03	18	72	2	IPR000998
Domain	MAM_2	PTPRK PTPRT	2.15e-03	18	72	2	PS50060
Domain	SRCR	CD163L1 TMPRSS3	2.94e-03	21	72	2	PF00530
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PTPRC PPP5C PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 DUSP1 TNS2 PFAS TANC1 AJUBA PTPRT NOTCH1	4.01e-08	1049	74	14	27880917
Pubmed	Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain.	PTPRC PTPRG PTPRZ1	9.22e-08	5	74	3	2169617
Pubmed	Maternal Cripto is required for proper uterine decidualization and peri-implantation uterine remodeling.	PTPRC NOTCH1 NOTCH4	1.10e-06	10	74	3	33590845
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	A1BG PTPRK OBSL1 NCAM2 LRIT3 PTPRT	1.33e-06	162	74	6	25826454
Pubmed	Human variation in alcohol response is influenced by variation in neuronal signaling genes.	PTPRG PTPRN2 PTPRZ1 FGF5 PTPRT DYNC1I1	1.82e-06	171	74	6	20201926
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MYT1L NR2C1 EGLN2 PPP5C PTPRK ADAM23 OBSL1 GATM NCAM2 LTBP3 USP9Y CTSB DYNC1I1	2.90e-06	1285	74	13	35914814
Pubmed	Large-scale structural analysis of the classical human protein tyrosine phosphatome.	PTPRC PTPRG PTPRK PTPRZ1	3.14e-06	47	74	4	19167335
Pubmed	Cell-fate transition and determination analysis of mouse male germ cells throughout development.	DDX4 NOTCH1 NOTCH4	3.31e-06	14	74	3	34824237
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RGMA HSPG2 EIF4ENIF1 TULP4 NICN1 FRMD8 PFAS LAMC3 TANC1 LTBP3 BTN3A2 NOTCH1	3.56e-06	1105	74	12	35748872
Pubmed	Differential patterns of NOTCH1-4 receptor expression are markers of glioma cell differentiation.	NOTCH1 NOTCH4	4.47e-06	2	74	2	24305720
Pubmed	Notch signaling in cancer.	NOTCH1 NOTCH4	4.47e-06	2	74	2	12496471
Pubmed	The IA-2 gene family: homologs in Caenorhabditis elegans, Drosophila and zebrafish.	PTPRN PTPRN2	4.47e-06	2	74	2	11206415
Pubmed	Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy.	NOTCH1 NOTCH4	4.47e-06	2	74	2	23389453
Pubmed	Notch signaling: from the outside in.	NOTCH1 NOTCH4	4.47e-06	2	74	2	11112321
Pubmed	PLCε knockdown inhibits prostate cancer cell proliferation via suppression of Notch signalling and nuclear translocation of the androgen receptor.	AR NOTCH1	4.47e-06	2	74	2	25796442
Pubmed	Thymosin beta4 induces angiogenesis through Notch signaling in endothelial cells.	NOTCH1 NOTCH4	4.47e-06	2	74	2	23749167
Pubmed	Lethal factor VII deficiency due to novel mutations in the F7 promoter: functional analysis reveals disruption of HNF4 binding site.	HNF4A F7	4.47e-06	2	74	2	22628013
Pubmed	Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2 β: identification of miR-153 target genes with functions related to IA-2β in pancreas and brain.	PTPRN PTPRN2	4.47e-06	2	74	2	23595248
Pubmed	Notch-1 and notch-4 receptors as prognostic markers in breast cancer.	NOTCH1 NOTCH4	4.47e-06	2	74	2	20444726
Pubmed	Deletion of Ia-2 and/or Ia-2β in mice decreases insulin secretion by reducing the number of dense core vesicles.	PTPRN PTPRN2	4.47e-06	2	74	2	21732083
Pubmed	Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2beta.	PTPRN PTPRN2	4.47e-06	2	74	2	18310453
Pubmed	Dense core vesicle proteins IA-2 and IA-2beta: metabolic alterations in double knockout mice.	PTPRN PTPRN2	4.47e-06	2	74	2	16306340
Pubmed	Common and female-specific roles of protein tyrosine phosphatase receptors N and N2 in mice reproduction.	PTPRN PTPRN2	4.47e-06	2	74	2	36611058
Pubmed	Assignment of Ptprn2, the gene encoding receptor-type protein tyrosine phosphatase IA-2beta, a major autoantigen in insulin-dependent diabetes mellitus, to mouse chromosome region 12F.	PTPRN PTPRN2	4.47e-06	2	74	2	9858807
Pubmed	Hepatitis B virus X protein activates Notch signaling by its effects on Notch1 and Notch4 in human hepatocellular carcinoma.	NOTCH1 NOTCH4	4.47e-06	2	74	2	26530164
Pubmed	Disruption of the transmembrane dense core vesicle proteins IA-2 and IA-2beta causes female infertility.	PTPRN PTPRN2	4.47e-06	2	74	2	16269463
Pubmed	Introduction to Notch signaling.	NOTCH1 NOTCH4	4.47e-06	2	74	2	25053477
Pubmed	TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3.	NR2C1 AR	4.47e-06	2	74	2	12949936
Pubmed	The dense core vesicle protein IA-2, but not IA-2β, is required for active avoidance learning.	PTPRN PTPRN2	4.47e-06	2	74	2	24662847
Pubmed	Mutation in the factor VII hepatocyte nuclear factor 4α-binding site contributes to factor VII deficiency.	HNF4A F7	4.47e-06	2	74	2	21760481
Pubmed	Clinicopathological significance of aberrant Notch receptors in intrahepatic cholangiocarcinoma.	NOTCH1 NOTCH4	4.47e-06	2	74	2	25031748
Pubmed	Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes.	PTPRN PTPRN2	4.47e-06	2	74	2	8798755
Pubmed	Critical role of endothelial Notch1 signaling in postnatal angiogenesis.	NOTCH1 NOTCH4	4.47e-06	2	74	2	17158336
Pubmed	Disturbances in the secretion of neurotransmitters in IA-2/IA-2beta null mice: changes in behavior, learning and lifespan.	PTPRN PTPRN2	4.47e-06	2	74	2	19361477
Pubmed	Notch-1 and Notch-4 biomarker expression in triple-negative breast cancer.	NOTCH1 NOTCH4	4.47e-06	2	74	2	22084425
Pubmed	Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma.	PTPRN PTPRN2	4.47e-06	2	74	2	8024693
Pubmed	Notch1 and Notch4 are markers for poor prognosis of hepatocellular carcinoma.	NOTCH1 NOTCH4	4.47e-06	2	74	2	23742774
Pubmed	Pathophysiologic changes in IA-2/IA-2β null mice are secondary to alterations in the secretion of hormones and neurotransmitters.	PTPRN PTPRN2	4.47e-06	2	74	2	25861885
Pubmed	Association of AXIN1 rs12921862 C/A and rs1805105 G/A and CTSB rs12898 G/A polymorphisms with papillary thyroid carcinoma: A case-control study.	CTSB AXIN1	4.47e-06	2	74	2	36510340
Pubmed	Dense-core vesicle proteins IA-2 and IA-2{beta} affect renin synthesis and secretion through the {beta}-adrenergic pathway.	PTPRN PTPRN2	4.47e-06	2	74	2	19019914
Pubmed	Receptor protein tyrosine phosphatases are expressed by cycling retinal progenitor cells and involved in neuronal development of mouse retina.	PTPRG PTPRK PTPRZ1	5.08e-06	16	74	3	18308476
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	HSPG2 EIF4ENIF1 PTPRN PTPRN2 TNS2 AJUBA USH1C NOTCH1 ALG13	5.78e-06	608	74	9	16713569
Pubmed	Notch receptor expression in human brain arteriovenous malformations.	NOTCH1 NOTCH4	1.34e-05	3	74	2	25846406
Pubmed	betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system.	PTPRN PTPRN2	1.34e-05	3	74	2	11086001
Pubmed	Multimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activity.	PTPRN PTPRN2	1.34e-05	3	74	2	12364328
Pubmed	FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.	FRMD8 FRMD8P1	1.34e-05	3	74	2	37527040
Pubmed	Novel RPTPγ and RPTPζ splice variants from mixed neuron-astrocyte hippocampal cultures as well as from the hippocampi of newborn and adult mice.	PTPRG PTPRZ1	1.34e-05	3	74	2	38952869
Pubmed	Differential expression of Notch genes in human osteoblastic cells.	NOTCH1 NOTCH4	1.34e-05	3	74	2	11836628
Pubmed	Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation.	MYT1L PTPRN2	1.34e-05	3	74	2	27153397
Pubmed	Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation.	NOTCH1 NOTCH4	1.34e-05	3	74	2	14988227
Pubmed	Identification of a functional hepatocyte nuclear factor 4 binding site in the neutral ceramidase promoter.	ASAH2 HNF4A	1.34e-05	3	74	2	20803549
Pubmed	Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axis.	HNF4A AR	1.34e-05	3	74	2	12944908
Pubmed	Notch signaling: cell fate control and signal integration in development.	NOTCH1 NOTCH4	1.34e-05	3	74	2	10221902
Pubmed	Protein tyrosine phosphatase zeta/RPTPbeta interacts with PSD-95/SAP90 family.	PTPRG PTPRZ1	1.34e-05	3	74	2	10521598
Pubmed	Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA-2, IA-2β, and GAD65.	PTPRN PTPRN2	1.34e-05	3	74	2	26148972
Pubmed	The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth.	FRMD8 FRMD8P1	1.34e-05	3	74	2	36720499
Pubmed	Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.	NOTCH1 NOTCH4	1.34e-05	3	74	2	28871079
Pubmed	Notch1 is pan-endothelial at the onset of flow and regulated by flow.	NOTCH1 NOTCH4	1.34e-05	3	74	2	25830332
Pubmed	NGS nominated CELA1, HSPG2, and KCNK5 as candidate genes for predisposition to Balkan endemic nephropathy.	HSPG2 CELA1	1.34e-05	3	74	2	24949484
Pubmed	Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches.	NOTCH1 NOTCH4	1.34e-05	3	74	2	18593923
Pubmed	Characterization of Notch Signalling Pathway Members in Normal Prostate, Prostatic Intraepithelial Neoplasia (PIN) and Prostatic Adenocarcinoma.	NOTCH1 NOTCH4	1.34e-05	3	74	2	26341090
Pubmed	Delta-like 4/Notch pathway is differentially regulated in benign and malignant thyroid tissues.	NOTCH1 NOTCH4	1.34e-05	3	74	2	22066479
Pubmed	Unique patterns of Notch1, Notch4 and Jagged1 expression in ovarian vessels during folliculogenesis and corpus luteum formation.	NOTCH1 NOTCH4	1.34e-05	3	74	2	15939383
Pubmed	Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease.	NOTCH1 NOTCH4	1.34e-05	3	74	2	19546852
Pubmed	Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg-like Cells, and Common EGFR Somatic Mutations.	AR NOTCH1	1.34e-05	3	74	2	34232601
Pubmed	NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.	NOTCH1 NOTCH4	1.34e-05	3	74	2	21679465
Pubmed	Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4.	DUSP1 NOTCH4	1.34e-05	3	74	2	34785669
Pubmed	Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset.	BTN3A3 BTN3A2	1.34e-05	3	74	2	22767497
Pubmed	The Ia-2β intronic miRNA, miR-153, is a negative regulator of insulin and dopamine secretion through its effect on the Cacna1c gene in mice.	PTPRN PTPRN2	1.34e-05	3	74	2	26141787
Pubmed	Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.	MAPK12 DUSP1 FGF5 HNF4A F7 AR AXIN1	1.45e-05	371	74	7	25241761
Pubmed	Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.	HNF4A NOTCH1 NOTCH4	2.32e-05	26	74	3	25446530
Pubmed	Notch signaling controls liver development by regulating biliary differentiation.	HNF4A NOTCH1 NOTCH4	2.32e-05	26	74	3	19369401
Pubmed	The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.	NOTCH1 NOTCH4	2.67e-05	4	74	2	24145721
Pubmed	A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.	NOTCH1 NOTCH4	2.67e-05	4	74	2	20069356
Pubmed	Expression and clinical significance of Notch receptors in human renal cell carcinoma.	NOTCH1 NOTCH4	2.67e-05	4	74	2	19404845
Pubmed	Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.	NOTCH1 NOTCH4	2.67e-05	4	74	2	28669409
Pubmed	Disruption of gene expression rhythms in mice lacking secretory vesicle proteins IA-2 and IA-2β.	PTPRN PTPRN2	2.67e-05	4	74	2	22785238
Pubmed	Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin.	NOTCH1 NOTCH4	2.67e-05	4	74	2	17984306
Pubmed	Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.	NOTCH1 NOTCH4	2.67e-05	4	74	2	11401408
Pubmed	Postnatal germ cell development during mini-puberty in the mouse does not require androgen receptor: implications for managing cryptorchidism.	AR DDX4	2.67e-05	4	74	2	25315959
Pubmed	Epileptic and developmental disorders of the speech cortex: ligand/receptor interaction of wild-type and mutant SRPX2 with the plasminogen activator receptor uPAR.	SRPX2 CTSB	2.67e-05	4	74	2	18718938
Pubmed	Functional conservation of mouse Notch receptor family members.	NOTCH1 NOTCH4	2.67e-05	4	74	2	8898100
Pubmed	Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties.	NOTCH1 NOTCH4	2.67e-05	4	74	2	36376768
Pubmed	The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules.	PTPRG PTPRZ1	2.67e-05	4	74	2	20133774
Pubmed	Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2.	BTN3A3 BTN3A2	2.67e-05	4	74	2	39142074
Pubmed	Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.	NOTCH1 NOTCH4	2.67e-05	4	74	2	23444212
Pubmed	Deregulated expression of Notch receptors in human hepatocellular carcinoma.	NOTCH1 NOTCH4	2.67e-05	4	74	2	17920003
Pubmed	Comparison of CD45 extracellular domain sequences from divergent vertebrate species suggests the conservation of three fibronectin type III domains.	PTPRC PTPRG	2.67e-05	4	74	2	8759740
Pubmed	Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.	NOTCH1 NOTCH4	2.67e-05	4	74	2	28061457
Pubmed	ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds.	NOTCH1 NOTCH4	2.67e-05	4	74	2	27354212
Pubmed	Evolutionary analysis of vertebrate Notch genes.	NOTCH1 NOTCH4	2.67e-05	4	74	2	11466531
Pubmed	Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.	NOTCH1 NOTCH4	2.67e-05	4	74	2	24151014
Pubmed	Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.	NOTCH1 NOTCH4	2.67e-05	4	74	2	10194420
Pubmed	Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.	NOTCH1 NOTCH4	2.67e-05	4	74	2	11459941
Pubmed	Amino-terminal enhancer of split gene AES encodes a tumor and metastasis suppressor of prostate cancer.	AR NOTCH1	2.67e-05	4	74	2	28178391
Pubmed	Notch1 deficiency results in decreased inflammation during wound healing and regulates vascular endothelial growth factor receptor-1 and inflammatory cytokine expression in macrophages.	NOTCH1 NOTCH4	2.67e-05	4	74	2	20739676
Pubmed	Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.	NOTCH1 NOTCH4	2.67e-05	4	74	2	18184405
Pubmed	Expression of NOTCH1, NOTCH4, HLA-DMA and HLA-DRA is synergistically associated with T cell exclusion, immune checkpoint blockade efficacy and recurrence risk in ER-negative breast cancer.	NOTCH1 NOTCH4	2.67e-05	4	74	2	35543859
Pubmed	Notch signaling in the mammalian central nervous system: insights from mouse mutants.	NOTCH1 NOTCH4	2.67e-05	4	74	2	15917835
Pubmed	Tissue-specific pioneer factors associate with androgen receptor cistromes and transcription programs.	HNF4A AR	2.67e-05	4	74	2	24451200
Cytoband	Ensembl 112 genes in cytogenetic band chrXq12	AR FRMD8P1	8.12e-04	26	74	2	chrXq12
Cytoband	Xq12	AR FRMD8P1	8.12e-04	26	74	2	Xq12
Cytoband	Ensembl 112 genes in cytogenetic band chr9q34	HMCN2 GBGT1 LAMC3 NOTCH1	1.92e-03	325	74	4	chr9q34
Cytoband	11q13.1	LTBP3 CTSW	4.70e-03	63	74	2	11q13.1
Cytoband	4q25	AP1AR LRIT3	5.30e-03	67	74	2	4q25
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRC PTPRG PTPRK PTPRN PTPRN2 PTPRZ1 PTPRT	1.59e-13	21	54	7	813
GeneFamily	Fibronectin type III domain containing	PTPRC PTPRG PTPRK PTPRZ1 NCAM2 PTPRT	7.95e-06	160	54	6	555
GeneFamily	Immunoglobulin like domain containing	A1BG HSPG2 HMCN2 PTPRK OBSL1 PTPRT	2.31e-05	193	54	6	594
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 HMCN2 OBSL1 NCAM2 LRIT3	1.17e-04	161	54	5	593
GeneFamily	Nuclear hormone receptors	NR2C1 HNF4A AR	4.21e-04	49	54	3	71
GeneFamily	Butyrophilins\|V-set domain containing\|C2-set domain containing	BTN3A3 BTN3A2	8.97e-04	15	54	2	458
GeneFamily	Cathepsins	CTSB CTSW	8.97e-04	15	54	2	470
Coexpression	BOYAULT_LIVER_CANCER_SUBCLASS_G1_DN	BTN3A3 GBE1 CTSB BTN3A2	4.69e-06	40	73	4	M1883
Coexpression	MARTINEZ_RESPONSE_TO_TRABECTEDIN	MGMT PTPRG PTPRK GBE1	1.16e-05	50	73	4	M5077
Coexpression	GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP	TMPRSS3 SHISA2 LTBP3 HNF4A WDFY2 DDX4	2.04e-05	200	73	6	M4559
Coexpression	GSE45365_CTRL_VS_MCMV_INFECTION_NK_CELL_UP	EGLN2 SRPX2 NICN1 TNS2 MRNIP AR	2.04e-05	200	73	6	M10026
Coexpression	GSE20715_0H_VS_6H_OZONE_LUNG_DN	HSPG2 EGLN2 PPP5C TULP4 TNS2 NOTCH1	2.04e-05	200	73	6	M4365
Coexpression	NABA_MATRISOME	HSPG2 EGLN2 SRPX2 HMCN2 ADAM23 CELA1 FGF5 LAMC3 LTBP3 CTSB F7 CTSW	2.07e-05	1008	73	12	MM17056
Coexpression	NABA_MATRISOME	HSPG2 EGLN2 SRPX2 HMCN2 ADAM23 CELA1 FGF5 LAMC3 LTBP3 CTSB F7 CTSW	2.46e-05	1026	73	12	M5889
Coexpression	NABA_ECM_REGULATORS	EGLN2 ADAM23 CELA1 CTSB F7 CTSW	5.39e-05	238	73	6	M3468
Coexpression	NABA_ECM_REGULATORS	EGLN2 ADAM23 CELA1 CTSB F7 CTSW	5.91e-05	242	73	6	MM17062
CoexpressionAtlas	Stromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5	HSPG2 PTPRG PTPRK DSG2 ASAH2 DUSP1 TNS2 AR NOTCH4	2.06e-05	456	71	9	GSM777032_500
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRZ1 GATM CELA1 FGF5 NCAM2 PTPRT	6.97e-07	187	74	6	16e55d802fc4e71878305e61ad03806aabd59537
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 PTPRZ1 GATM CELA1 FGF5 NCAM2	7.65e-07	190	74	6	ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 PTPRZ1 GATM CELA1 FGF5 NCAM2	7.65e-07	190	74	6	4971857eac9af17d66d673ed2ab7072639f60a10
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HSPG2 SRPX2 PTPRG OBSL1 TNS2 AR	9.44e-07	197	74	6	3bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HSPG2 SRPX2 PTPRG OBSL1 TNS2 AR	9.44e-07	197	74	6	17344464fdcc5ba0c03959696b97c195f11e644c
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HSPG2 SRPX2 PTPRG OBSL1 TNS2 AR	9.44e-07	197	74	6	5b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 PTPRG PTPRK TNS2 SHISA2	7.50e-06	162	74	5	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 PTPRG PTPRK TNS2 SHISA2	8.44e-06	166	74	5	89e2b8453180983533faccb4275867861876d7ee
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSG2 OBSL1 AJUBA RPL3L PTPRT	9.21e-06	169	74	5	05e12524d68d409fed386ffad233305683b4575b
ToppCell	P07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADAM23 PTPRZ1 GATM CELA1 NCAM2	1.00e-05	172	74	5	8d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYT1L HMCN2 PTPRN PTPRN2 KLHDC9	1.06e-05	174	74	5	742c73c9e090848b464323cb17579b86658c6792
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYT1L HMCN2 PTPRN PTPRN2 KLHDC9	1.06e-05	174	74	5	7fed9722e64c60843092f2ba71256e3043011ef6
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	MYT1L PTPRN PTPRN2 USH1C DYNC1I1	1.32e-05	182	74	5	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 MAPK12 ADAM23 GATM NOTCH4	1.32e-05	182	74	5	b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 PTPRZ1 GATM FGF5 NCAM2	1.39e-05	184	74	5	9f8cd5ab5af6c35a1be25d70a125b9a3f4dd667a
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 PTPRZ1 GATM CELA1 NCAM2	1.39e-05	184	74	5	a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 PTPRZ1 GATM FGF5 NCAM2	1.43e-05	185	74	5	3d1353dbcb60e2531ef67e1bd218b7bc4d7c7c9b
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 PTPRZ1 GATM FGF5 NCAM2	1.43e-05	185	74	5	995a8ddc3fd8e6879d8b5de8cbdefe232d34833b
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 PTPRZ1 GATM FGF5 NCAM2	1.46e-05	186	74	5	d8d559daff4aeef334d403fde4e3ee2e4a6086d0
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HSPG2 HMCN2 TNS2 TANC1 NOTCH4	1.46e-05	186	74	5	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 PTPRZ1 GATM CELA1 NCAM2	1.54e-05	188	74	5	8385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 PTPRZ1 GATM CELA1 NCAM2	1.54e-05	188	74	5	cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 ADAM23 DUSP1 GATM NOTCH1	1.70e-05	192	74	5	2bfac6b3956265205ca47d06888851ed68b65999
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 MAPK12 ADAM23 GATM NOTCH1	1.70e-05	192	74	5	5890076929598e88fe9d59a4e4e858b446746ce9
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 ADAM23 DUSP1 GATM NOTCH1	1.70e-05	192	74	5	d525f7f088a53110912600a7c9f6d33b9270d534
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 MAPK12 ADAM23 GATM NOTCH1	1.75e-05	193	74	5	4a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SRPX2 PTPRG SHISA2 TANC1 F7	1.75e-05	193	74	5	5e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 MAPK12 ADAM23 GATM NOTCH1	1.75e-05	193	74	5	d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 HMCN2 PTPRZ1 TNS2 NOTCH4	1.75e-05	193	74	5	cc355b2ed6510619cad969ae074126d7c8db784d
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 MAPK12 ADAM23 TANC1 NOTCH1	1.75e-05	193	74	5	d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	MYT1L PTPRN PTPRN2 NICN1 DYNC1I1	1.75e-05	193	74	5	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	facs-Liver-Non-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 ADAM23 GATM TANC1 NOTCH1	1.75e-05	193	74	5	8084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell	IPF-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	HSPG2 PTPRG TANC1 USH1C NOTCH4	1.75e-05	193	74	5	ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 MAPK12 ADAM23 GATM NOTCH1	1.84e-05	195	74	5	12ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PTPRZ1 ASAH2 GATM AR PTPRT	1.84e-05	195	74	5	6c9c58322c1df891bb4bab56dacb542c8777bb7d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYT1L PTPRN2 ADAM23 KCTD16 DYNC1I1	1.88e-05	196	74	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	HSPG2 TANC1 PTPRT DYNC1I1 NOTCH4	1.88e-05	196	74	5	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 ADAM23 GATM TANC1 NOTCH1	1.93e-05	197	74	5	deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 ADAM23 GATM TANC1 NOTCH1	1.93e-05	197	74	5	a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYT1L PTPRN2 ADAM23 KCTD16 DYNC1I1	1.98e-05	198	74	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYT1L PTPRN2 ADAM23 KCTD16 DYNC1I1	1.98e-05	198	74	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYT1L PTPRN2 ADAM23 KCTD16 DYNC1I1	1.98e-05	198	74	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Parenchyma_COVID-19-Immune-TX-MoAM-4\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	A1BG PTPRC CD163L1 GBGT1 GBE1	1.98e-05	198	74	5	a7eed9eeb728a8796e2780090cc244856efd8c65
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 ADAM23 GATM TANC1 NOTCH1	1.98e-05	198	74	5	f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	EGLN2 ZFR2 GBGT1 USH1C	4.20e-05	116	74	4	f32f7eddfe33adb3b5cf7c34667a481a305c5163
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HSPG2 SRPX2 GBGT1 LAMC3	7.36e-05	134	74	4	b959899c89d3a0363a3cd2309155280e0fe5ba88
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_3\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	PTPRZ1 OBSL1 TKTL2 NOTCH1	7.80e-05	136	74	4	5e209185b5f6e9347829fc9066f0b2c3711df057
ToppCell	LPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-T-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PTPRC ADAM23 CTSW AXIN1	8.49e-05	139	74	4	ecc2a6ecc27748c50885cd4f0ad8a8cd1252aee6
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC GBGT1 CTSW DDX4	9.22e-05	142	74	4	c2a3cd9998fd9a8e6b2665347ca5c32511776488
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC GBGT1 CTSW DDX4	9.99e-05	145	74	4	23a1ee986774725a9f5a9154fbbd023031fb0452
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B\|343B / Donor, Lineage, Cell class and subclass (all cells)	PTPRC F7 LRIT3 CTSW	1.26e-04	154	74	4	886e7cd01cb48ca3e97debeea2b1f100b09d47e6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HMCN2 ADAM23 PTPRZ1 NCAM2	1.26e-04	154	74	4	30cb4bb297fa815adb829f3b5cafca56fcbcb810
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell-Schwann_Cell_/_Neural\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HMCN2 ADAM23 PTPRZ1 NCAM2	1.26e-04	154	74	4	ade094e2947761a0a34daa8fcff3e9ea8437e4a5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HMCN2 ADAM23 PTPRZ1 NCAM2	1.26e-04	154	74	4	42bd8f88fd075a2d4edde394785decad88a2660a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Neural-neural_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HMCN2 ADAM23 PTPRZ1 NCAM2	1.26e-04	154	74	4	6425d9861148586466febd6eceae1b1f9b9a14c1
ToppCell	droplet-Fat-Mat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSG2 SHISA2 USH1C HNF4A	1.32e-04	156	74	4	cfd7f56f3155db677684827607e9008e975dbe70
ToppCell	droplet-Fat-Mat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSG2 SHISA2 USH1C HNF4A	1.32e-04	156	74	4	0d79b4172896574b00faf00e87254f68d76f5512
ToppCell	droplet-Fat-Mat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSG2 SHISA2 USH1C HNF4A	1.32e-04	156	74	4	f09150aacb6121f913648ed3918f9cd4f22c61f2
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYT1L PTPRN PTPRN2 USH1C	1.43e-04	159	74	4	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	HSPG2 SRPX2 TNS2 LAMC3	1.43e-04	159	74	4	34c90711c5857cf6ada7b3acff99f1d48c7caf29
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	MYT1L PTPRN2 NCAM2 PTPRT	1.43e-04	159	74	4	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HSPG2 SRPX2 GBGT1 LAMC3	1.43e-04	159	74	4	92049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM23 PTPRZ1 NCAM2 SHISA2	1.46e-04	160	74	4	14dfa519e68bab4bce890ddb66fa7763f18d9f19
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM23 PTPRZ1 NCAM2 SHISA2	1.46e-04	160	74	4	839bbdfd4e4c7b48260c8bfb7670378634405e1d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM23 PTPRZ1 NCAM2 SHISA2	1.46e-04	160	74	4	5b7789d4668ed7732babedc32d812233b430e0bd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM23 PTPRZ1 NCAM2 SHISA2	1.46e-04	160	74	4	bba1486faaad5299e10f4fe17c6d149c28dc2560
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC CD163L1 FGF5 CTSW	1.50e-04	161	74	4	140b3c7077947c541cff54f6754e2df968345f4d
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC CD163L1 FGF5 CTSW	1.53e-04	162	74	4	16f9fbcaa0093ffc5a2a5e32db6040e2cb519d47
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MGMT CD163L1 TNS2 LAMC3	1.53e-04	162	74	4	c5eee02836efde2108534679850c28d2b2cfce3f
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAM23 PTPRZ1 GATM NCAM2	1.61e-04	164	74	4	3caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	HMCN2 DSG2 PTPRN SHISA2	1.61e-04	164	74	4	9b4a6007abae992db871d9f6f731d5af724de30d
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYT1L PTPRN PTPRN2 USH1C	1.61e-04	164	74	4	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	MYT1L PTPRN KCTD16 NCAM2	1.64e-04	165	74	4	9795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RGMA HSPG2 BTN3A3 TANC1	1.68e-04	166	74	4	9d4b44eb56ad38c26aed73444edf389abca6bdf6
ToppCell	droplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRC DUSP1 CTSB RPL3L	1.76e-04	168	74	4	d823979335ac6b5d1f062ebb741c759d2f919dbf
ToppCell	facs-Kidney\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC GATM USH1C HNF4A	1.76e-04	168	74	4	d2f17a470e04f8f0edb111894027bcfc6ee1a12f
ToppCell	droplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRC DUSP1 CTSB RPL3L	1.76e-04	168	74	4	f377ff4c066a9857ad14d245e56325ad220e22e1
ToppCell	facs-Skin-Skin_Anagen-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC CELA1 FGF5 CTSW	1.80e-04	169	74	4	630d921aa8fb5681d06a4e09b833855c374be484
ToppCell	facs-Skin-Skin_Anagen-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC CELA1 FGF5 CTSW	1.80e-04	169	74	4	468284d4a3a0557aed04eadb1aba2317babc6904
ToppCell	facs-Skin-Skin_Anagen-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC CELA1 FGF5 CTSW	1.80e-04	169	74	4	6f765e142d127545e622fe24b5287cd6e9706ccc
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYT1L PTPRN PTPRN2 USH1C	1.80e-04	169	74	4	96a2aec9acf8a6f966973c035e5ade456cf47772
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC DUSP1 CTSB RPL3L	1.80e-04	169	74	4	411556e93adcbb7e4d79b02f3dc72963ec8a0759
ToppCell	droplet-Lung-LUNG-30m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC DUSP1 CTSB RPL3L	1.80e-04	169	74	4	39b1acfd099abb9de18c29c05c7a67709ea76775
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYT1L PTPRN PTPRN2 USH1C	1.80e-04	169	74	4	b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCell	Mild_COVID-19-Myeloid-MoAM5\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	SRPX2 GBGT1 SHISA2 TANC1	1.84e-04	170	74	4	b2daf46ab5a49590ede8f75e4240bfe6e9d8b764
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHISA2 AJUBA HNF4A AR	1.84e-04	170	74	4	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	PUS3 TNS2 USP9Y KLHDC9	1.84e-04	170	74	4	4a19c7e3bb0f9c2601a10debe7000066789b4150
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HSPG2 MAPK12 PTPRG NOTCH4	1.88e-04	171	74	4	1597459c971d6befa991d59dc66b41b6a522f797
ToppCell	droplet-Lung-nan-21m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC DUSP1 CTSB RPL3L	1.93e-04	172	74	4	51bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCell	droplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC DUSP1 CTSB RPL3L	1.93e-04	172	74	4	be4dd4ba8d7a651677c797c25fd75f14e627415a
ToppCell	mild-Others-CD34+_GATA2+_cells\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	HSPG2 MAPK12 DSG2 OBSL1	1.93e-04	172	74	4	379f6f271e653d5e404851e51a189bd582bb0f43
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 MAPK12 ADAM23 GATM	1.93e-04	172	74	4	a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRN PTPRN2 CTSW DYNC1I1	2.01e-04	174	74	4	ecdff386d7f0bc57c170a2c1f4deae5ba7e431b5
ToppCell	facs-Spleen-nan-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP1 CTSB AR NOTCH1	2.01e-04	174	74	4	096bc6f1889f2bbadfe1e1a3eb6ae569aaa2ee7d
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PTPRC ASAH2 F7 CTSW	2.06e-04	175	74	4	cc2428150987911d0d382e8177918724aa69f85c
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RGMA DUSP1 MRNIP CTSB	2.06e-04	175	74	4	6374ab186d7ccf7f6dfb858267edba8962789e15
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRZ1 CD163L1 LAMC3 CTSW	2.06e-04	175	74	4	5a9160a9d05e01d945e77fd81bb0bd87139545cd
ToppCell	facs-Skin-Telogen-3m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC CD163L1 CELA1 CTSW	2.10e-04	176	74	4	3d372c1d527fcc118d1e5809f2524fc387682472
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 MAPK12 ADAM23 GATM	2.10e-04	176	74	4	3494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCell	facs-Skin-Telogen-3m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRC CD163L1 CELA1 CTSW	2.10e-04	176	74	4	7b3f3d9b33770edf294cee0eccaf8a46f9331461
Computational	Neighborhood of ITGAL	BTN3A3 PTPRC BTN3A2 CTSW	7.82e-05	55	45	4	GNF2_ITGAL
Computational	Neighborhood of ZAP70	BTN3A3 BTN3A2 CTSW	1.67e-04	26	45	3	GNF2_ZAP70
Computational	Neighborhood of CASP8	BTN3A3 PTPRC BTN3A2	1.87e-04	27	45	3	GNF2_CASP8
Computational	Neighborhood of SNRK	BTN3A3 PTPRC BTN3A2	2.09e-04	28	45	3	GNF2_SNRK
Computational	Neighborhood of JAK1	BTN3A3 PTPRC CTSW	3.12e-04	32	45	3	GNF2_JAK1
Disease	diabetes mellitus (implicated_via_orthology)	PTPRN PTPRN2 F7	3.48e-05	26	72	3	DOID:9351 (implicated_via_orthology)
Disease	type 1 diabetes mellitus (is_implicated_in)	PTPRN PTPRN2 F7 NOTCH4	5.68e-05	85	72	4	DOID:9744 (is_implicated_in)
Disease	atopic eczema, psoriasis	MYT1L MGMT PTPRN2	9.39e-05	36	72	3	EFO_0000274, EFO_0000676
Disease	hemangiopericytoma (is_marker_for)	NOTCH1 NOTCH4	2.09e-04	9	72	2	DOID:264 (is_marker_for)
Disease	Necrosis	MGMT GATM CTSB	3.34e-04	55	72	3	C0027540
Disease	neuroticism measurement	MYT1L MGMT PPP5C PTPRG GBE1 LTBP3 CTSB BTN3A2 NOTCH4	3.60e-04	909	72	9	EFO_0007660
Disease	hyperglycemia (is_marker_for)	HSPG2 F7	4.50e-04	13	72	2	DOID:4195 (is_marker_for)
Disease	Pneumoconiosis	PTPRZ1 TMPRSS3	5.24e-04	14	72	2	C0032273
Disease	Bagassosis	PTPRZ1 TMPRSS3	5.24e-04	14	72	2	C0004681
Disease	preeclampsia, hypertension, pregnancy-induced	FGF5 TNS2	6.89e-04	16	72	2	EFO_0000668, MONDO_0024664
Disease	multiple sclerosis (is_implicated_in)	RGMA PTPRC NOTCH4	7.67e-04	73	72	3	DOID:2377 (is_implicated_in)
Disease	alkaline phosphatase measurement	HSPG2 MGMT GBGT1 GATB LTBP3 HNF4A CTSB NOTCH1 AXIN1	7.94e-04	1015	72	9	EFO_0004533
Disease	response to antiviral drug	RGMA NCAM2	8.76e-04	18	72	2	EFO_0010123
Disease	Glioblastoma	MGMT CTSB NOTCH1	9.64e-04	79	72	3	C0017636
Disease	age of onset of asthma	PTPRC LTBP3 BTN3A2	9.64e-04	79	72	3	OBA_2001001
Disease	citrulline measurement	HMCN2 CTSB	1.08e-03	20	72	2	EFO_0009777
Disease	Adenocarcinoma of prostate	AR AXIN1	1.08e-03	20	72	2	C0007112
Disease	breast cancer (is_marker_for)	MGMT DUSP1 CTSB F7	1.10e-03	185	72	4	DOID:1612 (is_marker_for)
Disease	Giant Cell Glioblastoma	MGMT CTSB NOTCH1	1.15e-03	84	72	3	C0334588
Disease	systemic scleroderma	MYT1L TULP4 NOTCH4	1.19e-03	85	72	3	EFO_0000717
Disease	Carcinoma, Pancreatic Ductal	NOTCH1 NOTCH4	1.57e-03	24	72	2	C0887833
Disease	Squamous cell carcinoma of esophagus	MGMT AJUBA NOTCH1	1.64e-03	95	72	3	C0279626
Disease	Cerebral Astrocytoma	AR NOTCH1	1.70e-03	25	72	2	C0750935
Disease	Intracranial Astrocytoma	AR NOTCH1	1.70e-03	25	72	2	C0750936
Disease	Pilocytic Astrocytoma	AR NOTCH1	1.70e-03	25	72	2	C0334583
Disease	Astrocytoma	AR NOTCH1	1.70e-03	25	72	2	C0004114
Disease	Juvenile Pilocytic Astrocytoma	AR NOTCH1	1.70e-03	25	72	2	C0280783
Disease	Diffuse Astrocytoma	AR NOTCH1	1.70e-03	25	72	2	C0280785
Disease	Grade I Astrocytoma	AR NOTCH1	1.70e-03	25	72	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	AR NOTCH1	1.70e-03	25	72	2	C0205768
Disease	Mixed oligoastrocytoma	AR NOTCH1	1.70e-03	25	72	2	C0547065
Disease	Childhood Cerebral Astrocytoma	AR NOTCH1	1.70e-03	25	72	2	C0338070
Disease	Gemistocytic astrocytoma	AR NOTCH1	1.84e-03	26	72	2	C0334581
Disease	Protoplasmic astrocytoma	AR NOTCH1	1.84e-03	26	72	2	C0334580
Disease	Fibrillary Astrocytoma	AR NOTCH1	1.84e-03	26	72	2	C0334582
Disease	obesity (implicated_via_orthology)	HNF4A AR NOTCH1 NOTCH4	1.91e-03	215	72	4	DOID:9970 (implicated_via_orthology)
Disease	Anaplastic astrocytoma	AR NOTCH1	1.98e-03	27	72	2	C0334579
Disease	transforming growth factor beta measurement	RGMA CELA1	1.98e-03	27	72	2	EFO_0004818
Disease	arteriosclerosis (is_marker_for)	F7 NOTCH4	2.28e-03	29	72	2	DOID:2349 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VLVHCSAGVGRTGTY	PTPRG	1056	P23470
VSAVYERGAAERHGG	USH1C	481	Q9Y6N9
TSGYCVGRRGHSSGK	ALG13	761	Q9NP73
LSYFGGVCSRTRGVG	ADAM23	401	O75077
GYEDGGIHLECRSTG	BTN3A3	156	O00478
GLVSGGLYESHVGCR	CTSB	166	P07858
IDEYVHRIGRTGRCG	DDX4	621	Q9NQI0
RHSVTGYGDCAVGAR	AJUBA	261	Q96IF1
AFARVDGGSCHRRGA	GATB	16	O75879
GGGSKYFRTCSRGEH	AP1AR	26	Q63HQ0
GDSRCAGRVEIYHDG	CD163L1	1041	Q9NR16
LGARTHNYGIGAAAC	NDUFA11	101	Q86Y39
SGRHYGAVTCEGCKG	NR2C1	121	P13056
GEYVCHVSNGAGSRE	HSPG2	2596	P98160
IIVHCSDGAGRSGTY	PTPRN2	941	Q92932
LQAYGEGSGADCRRH	MRNIP	41	Q6NTE8
LNAVALGDGGHYTCR	A1BG	266	P04217
GSGCREAQHDSYVGL	DSG2	596	Q14126
GDYRFRICTVSGHGR	OBSL1	586	O75147
IVHCSDGAGRTGTYI	PTPRN	906	Q16849
THGGTYRCFGSFRDA	KIR2DS4	191	P43632
AGTCHVVDRRGVADY	NOTCH1	71	P46531
ITVGYRGSCTLGREG	KCTD16	166	Q68DU8
CLRGGSRGAEAVHYI	GATM	6	P50440
SSDGGCEAALGTHYR	FRMD8	241	Q9BZ67
GTYECTAVSRAGTGR	HMCN2	491	Q8NDA2
ITGSHVGDEGRYQCV	HMCN2	1496	Q8NDA2
GYHIGVGRADCTGQV	ASAH2	101	Q9NR71
HRVVCSSGAVGNYSG	MGMT	146	P16455
SSDGGCEAALGTHYR	FRMD8P1	241	Q9BZ68
EGTVYTACRHGSKAG	DYNC1I1	461	O14576
AICGDRATGKHYGAS	HNF4A	61	P41235
TCDYHGRNDGSGSRL	LRIT3	26	Q3SXY7
CRYGDLASLHGAGAA	AR	406	P10275
GGSRYHTCGGTLIRQ	CELA1	41	Q9UNI1
VHCSAGVGRTGTYIV	PTPRZ1	1931	P23471
RCVIRSDGGSGVSNY	PTPRT	266	O14522
RRTGSLYCRVGIGFH	FGF5	86	P12034
EDVGGRGECYSIRTH	BECN2	386	A8MW95
RGYESFGVHRCADGG	GBE1	71	Q04446
GGQVARVYEFTRGCH	GBGT1	266	Q8N5D6
GGRVFVHCQAGISRS	DUSP1	251	P28562
HGARSRGYSESVGAA	AXIN1	571	O15169
GYFRLHRGSNTCGIT	CTSW	341	P56202
GYEDGGIHLECRSTG	BTN3A2	156	P78410
GYRLHVGAGGRSCVD	LTBP3	646	Q9NS15
HSCTELRGRFYLVGG	KLHDC9	31	Q8NEP7
HCAGRLGSYVINGRT	EGLN2	266	Q96KS0
HCSAGAGRTGCYIVI	PTPRK	1081	Q15262
GRGCHRYSELYGRTD	TAF3	46	Q5VWG9
YHRCGRTDKGVSAFG	PUS3	111	Q9BZE2
RVGCSIARAGQKGYH	RPL3L	261	Q92901
QGCATVGHFGVYTRV	F7	426	P08709
AEGYEVAHGGRCVTV	PPP5C	431	P53041
HTSARIGRFDVDGCY	NICN1	191	Q9BSH3
LLAAGARASGEYCHG	SHISA2	26	Q6UWI4
GTFTTRAGCGHFGDR	TANC1	1586	Q9C0D5
GGAYSHCRSLSGVGA	NOTCH4	1891	Q99466
RTCRGDLAYHSAVHG	RGMA	91	Q96B86
FGGGCHVTAAVSSRR	EIF4ENIF1	121	Q9NRA8
ACGHRRGYSSRIVGG	TMPRSS3	206	P57727
GRGVVGVTFTSSHCR	TULP4	51	Q9NRJ4
VSCTGADAYAAHIRG	ZFR2	326	Q9UPR6
HCSESGQRLGGYRTS	WDFY2	141	Q96P53
GRYDCEAASRIGGHQ	NCAM2	376	O15394
HCDGGYDRQGTPSRV	SRPX2	291	O60687
CTGRGAHVVAGTAGY	PFAS	336	O15067
HYREGGIGEAVCAAV	TKTL2	566	Q9H0I9
TAIGYGHVRAVAEAC	USP9Y	1161	O00507
ASVGIRHGSRRYGVC	ZBTB10	791	Q96DT7
VHCSAGVGRTGTYIG	PTPRC	851	P08575
VTCYHKGGRGTDRTL	TNS2	366	Q63HR2
GAYGAVCSAVDGRTG	MAPK12	36	P53778
CTFDRELFRSTGHGG	LAMC3	336	Q9Y6N6
CDGSGHVSGKYARHR	MYT1L	36	Q9UL68