Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncAMP binding

RAPGEF4 CNBD2 RAPGEF2

4.12e-0525543GO:0030552
GeneOntologyMolecularFunctioncyclic nucleotide binding

RAPGEF4 CNBD2 RAPGEF2

1.59e-0439543GO:0030551
GeneOntologyCellularComponentmitochondrial large ribosomal subunit

MRPL15 MRPL10 MRPL2

4.32e-0457543GO:0005762
GeneOntologyCellularComponentorganellar large ribosomal subunit

MRPL15 MRPL10 MRPL2

4.32e-0457543GO:0000315
MousePhenoabnormal hepatobiliary system development

FOXM1 ELOA RAPGEF2 BRD1 PTK2

2.34e-0674415MP:0003943
MousePhenodecreased hepatoblast number

FOXM1 BRD1

8.39e-062412MP:0012243
MousePhenoenlarged allantois

RTEL1 RAPGEF2 PTK2

1.04e-0515413MP:0004556
MousePhenoabnormal hepatoblast morphology

FOXM1 BRD1

8.35e-055412MP:0012240
DomaincNMP

RAPGEF4 CNBD2 RAPGEF2

1.36e-0434553SM00100
DomaincNMP_binding

RAPGEF4 CNBD2 RAPGEF2

1.36e-0434553PF00027
DomaincNMP-bd_dom

RAPGEF4 CNBD2 RAPGEF2

1.48e-0435553IPR000595
DomainCNMP_BINDING_3

RAPGEF4 CNBD2 RAPGEF2

1.48e-0435553PS50042
DomaincNMP-bd-like

RAPGEF4 CNBD2 RAPGEF2

1.89e-0438553IPR018490
Domain-

RAPGEF4 CNBD2 RAPGEF2

3.81e-04485532.60.120.10
DomainRmlC-like_jellyroll

RAPGEF4 CNBD2 RAPGEF2

4.55e-0451553IPR014710
DomainRasGEFN

RAPGEF4 RAPGEF2

1.56e-0320552SM00229
DomainRasGEF_N

RAPGEF4 RAPGEF2

1.72e-0321552PF00618
DomainRas-like_Gua-exchang_fac_N

RAPGEF4 RAPGEF2

1.89e-0322552IPR000651
DomainRASGEF_NTER

RAPGEF4 RAPGEF2

1.89e-0322552PS50212
DomainUbiquitin-rel_dom

RAPGEF4 RAPGEF2 FRMD4B PTK2

2.10e-03184554IPR029071
DomainRASGEF_CAT

RAPGEF4 RAPGEF2

3.29e-0329552PS50009
DomainRasGEF

RAPGEF4 RAPGEF2

3.51e-0330552PF00617
Domain-

RAPGEF4 RAPGEF2

3.51e-03305521.10.840.10
DomainRas_GEF_dom

RAPGEF4 RAPGEF2

3.51e-0330552IPR023578
DomainRASGEF_cat_dom

RAPGEF4 RAPGEF2

3.51e-0330552IPR001895
DomainRasGEF

RAPGEF4 RAPGEF2

3.51e-0330552SM00147
DomainCNMP_BINDING_1

RAPGEF4 CNBD2

3.99e-0332552PS00888
DomainCNMP_BINDING_2

RAPGEF4 CNBD2

3.99e-0332552PS00889
DomainRA

RAPGEF4 RAPGEF2

5.03e-0336552PF00788
DomainRA_dom

RAPGEF4 RAPGEF2

6.18e-0340552IPR000159
DomainFERM_M

FRMD4B PTK2

8.11e-0346552PF00373
DomainHEAT

INTS4 UTP20

8.81e-0348552PF02985
DomainFERM_central

FRMD4B PTK2

9.16e-0349552IPR019748
DomainFERM_domain

FRMD4B PTK2

9.16e-0349552IPR000299
DomainFERM_1

FRMD4B PTK2

9.53e-0350552PS00660
DomainFERM_2

FRMD4B PTK2

9.53e-0350552PS00661
DomainFERM_3

FRMD4B PTK2

9.53e-0350552PS50057
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DOCK5 NCOR2 ZNF609 POM121 KLF5 PIK3R3 MGA PTK2 NUP153

2.81e-0843056935044719
Pubmed

A human MAP kinase interactome.

VRK2 POM121 COBLL1 LAMA4 RAPGEF2 MGA PTK2 NUP153

1.08e-0648656820936779
Pubmed

Phosphohistidine signaling promotes FAK-RB1 interaction and growth factor-independent proliferation of esophageal squamous cell carcinoma.

RB1 PTK2

2.55e-06256236513743
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

DOCK5 NCOR2 VRK2 ZNF609 CHERP KLF5 INTS4 UTP20 MGA TAPBP NUP153

5.79e-061294561130804502
Pubmed

The N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrest.

RB1 PIK3R3

7.63e-06356212588990
Pubmed

Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase.

RAPGEF2 PTK2

7.63e-06356211799111
Pubmed

Circ-PTK2 promotes the proliferation and suppressed the apoptosis of acute myeloid leukemia cells through targeting miR-330-5p/FOXM1 axis.

FOXM1 PTK2

7.63e-06356233126007
Pubmed

Human RTEL1 Interacts with KPNB1 (Importin β) and NUP153 and Connects Nuclear Import to Nuclear Envelope Stability in S-Phase.

RTEL1 NUP153

7.63e-06356238132118
Pubmed

Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase.

RB1 PTK2

7.63e-06356215640164
Pubmed

FOXM1 transcriptionally regulates expression of integrin β1 in triple-negative breast cancer.

FOXM1 PTK2

7.63e-06356228361350
Pubmed

FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression.

RB1 PTK2

7.63e-06356236857183
Pubmed

KLF5 promotes cell migration by up-regulating FYN in bladder cancer cells.

KLF5 PTK2

7.63e-06356226786295
Pubmed

FOXM1 is required for small cell lung cancer tumorigenesis and associated with poor clinical prognosis.

FOXM1 RB1

1.52e-05456234155349
Pubmed

Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression.

FOXM1 RB1

1.52e-05456226243836
Pubmed

Mammalian mitochondrial ribosomal proteins (2). Amino acid sequencing, characterization, and identification of corresponding gene sequences.

MRPL15 MRPL2

1.52e-05456210593885
Pubmed

Insulin-like growth factor-1 receptor signaling increases the invasive potential of human epidermal growth factor receptor 2-overexpressing breast cancer cells via Src-focal adhesion kinase and forkhead box protein M1.

FOXM1 PTK2

1.52e-05456225391374
Pubmed

KLF5-induced BBOX1-AS1 contributes to cell malignant phenotypes in non-small cell lung cancer via sponging miR-27a-5p to up-regulate MELK and activate FAK signaling pathway.

KLF5 PTK2

1.52e-05456233931086
Pubmed

Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation.

IL1RAPL1 ST7 PTK2

1.72e-053156319736351
Pubmed

Plk1 Regulates the Repressor Function of FoxM1b by inhibiting its Interaction with the Retinoblastoma Protein.

FOXM1 RB1

2.54e-05556228387346
Pubmed

Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase.

FOXM1 RB1

2.54e-05556216314512
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ELOA NCOR2 VRK2 ZNF609 ST7 PIK3R3 INTS4 ELP3 NUP153

4.23e-05104956927880917
Pubmed

SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta.

NCOR2 KLF5

5.32e-05756218500350
Pubmed

Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes.

PIK3R3 PTK2

7.09e-05856222402981
Pubmed

A dual Keap1 and p47phox inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis.

RB1 NCF2

7.09e-05856236163178
Pubmed

Forkhead box M1B transcriptional activity requires binding of Cdk-cyclin complexes for phosphorylation-dependent recruitment of p300/CBP coactivators.

FOXM1 RB1

7.09e-05856215024056
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

ZNF609 CHERP KLF5 INTS4 MGA

7.25e-0526856533640491
Pubmed

Structures of the human mitochondrial ribosome in native states of assembly.

MRPL15 MRPL10 MRPL2

8.26e-055256328892042
Pubmed

Structure of the large ribosomal subunit from human mitochondria.

MRPL15 MRPL10 MRPL2

8.26e-055256325278503
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

ZNF609 KLF5 INTS4 MGA

9.24e-0514656423892456
Pubmed

Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase.

FOXM1 CHERP RB1 MGA

9.74e-0514856422898364
Pubmed

The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.

MRPL15 MRPL10 MRPL2

1.15e-045856311543634
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

UBE2J1 ELOA VRK2 ZNF609 CHERP MGA FRMD4B

1.70e-0473356734672954
Pubmed

Identification and characterization of nardilysin as a novel dimethyl H3K4-binding protein involved in transcriptional regulation.

NCOR2 COBLL1

1.96e-041356222294699
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

FOXM1 DOCK5 NCOR2 POM121 CHERP LIMCH1 MGA

2.02e-0475456735906200
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

NCOR2 ZNF609 CHERP NUP153

2.07e-0418056435198878
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

FOXM1 ELOA NCOR2 TRAPPC10 UTP20 LIMCH1 NUP153

2.37e-0477456715302935
Pubmed

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

OR51I1 OR51M1

2.64e-041556211121057
Pubmed

MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism.

RTEL1 ELP3

2.64e-041556222678361
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

POM121 NUP153

2.64e-041556214697343
Pubmed

Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.

OR51I1 OR51M1

2.64e-041556210220430
Pubmed

Expression analysis of mammalian mitochondrial ribosomal protein genes.

MRPL15 MRPL10 MRPL2

2.87e-047956332987154
Pubmed

Genetic predictors of fibrin D-dimer levels in healthy adults.

ABCA4 ABO

3.01e-041656221502573
Pubmed

Structure and Function of the Mitochondrial Ribosome.

MRPL15 MRPL10 MRPL2

3.20e-048256327023846
Pubmed

Mapping the mammalian ribosome quality control complex interactome using proximity labeling approaches.

UBE2J1 MRPL15 MRPL10 MRPL2

3.20e-0420256429540532
Pubmed

Laminin α1 is essential for mouse cerebellar development.

LAMA4 PTK2

3.41e-041756221983115
Pubmed

The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature.

FOXM1 LAMA4

4.28e-041956215817462
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

FOXM1 ELOA NCOR2 RB1 ZNF200 BRD1 ANKRD53

5.01e-0487756720211142
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK5 NCOR2 ZNF609 RTEL1 ST7 PIK3R3 LIMCH1 RAPGEF2 PTK2

5.81e-04148956928611215
Pubmed

BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.

NCOR2 ZNF609

6.87e-042456233722704
Pubmed

Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box M1 transcription factor.

FOXM1 LAMA4

6.87e-042456217366632
Pubmed

Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.

POM121 NUP153

8.07e-042656212228227
Pubmed

Elongin A regulates transcription in vivo through enhanced RNA polymerase processivity.

ELOA INTS4

8.07e-042656233298525
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

NCOR2 VRK2 ZNF609 POM121 NUP153

8.44e-0445756532344865
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOR2 RAPGEF4 LIMCH1 RAPGEF2 MGA PTK2 NUP153

8.69e-0496356728671696
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

NCOR2 ZNF609

8.71e-042756223395962
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

NCOR2 LIMCH1 NUP153

9.26e-0411856330979931
Pubmed

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.

VRK2 POM121 NUP153

9.95e-0412156322412018
Pubmed

Integrated structural analysis of the human nuclear pore complex scaffold.

POM121 NUP153

1.08e-033056224315095
Pubmed

The Structure Inventory of the Nuclear Pore Complex.

POM121 NUP153

1.08e-033056227016207
Pubmed

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.

RB1 LIMCH1 MGA

1.09e-0312556321654808
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

UBE2J1 ELOA UTP20 NCF2

1.16e-0328556432838362
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

POM121 RTEL1 COBLL1 MGA SLC7A14

1.18e-0349356515368895
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

DOCK5 ELOA ZNF609 POM121 RB1 COBLL1 TRAPPC10 LUM

1.19e-03132156827173435
Pubmed

The functional interactome landscape of the human histone deacetylase family.

NCOR2 ZNF609 RB1 NUP153

1.22e-0328956423752268
Pubmed

KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.

ELOA NCOR2 CHERP

1.22e-0313056335545047
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

ZNF609 MRPL15 INTS4 UTP20 LIMCH1 NUP153

1.32e-0375456633060197
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

ELOA NCOR2 UTP20 ELP3

1.37e-0329856430737378
InteractionKLF15 interactions

NCOR2 ZNF609 MRPL15 RB1 PIK3R3 MRPL10 MGA

9.14e-06290527int:KLF15
Cytoband6p22.3

NHLRC1 NUP153

1.46e-03465626p22.3
Cytoband11p15.4

OR51S1 OR51I1 OR51M1

1.90e-0320056311p15.4
GeneFamilyOlfactory receptors, family 51

OR51S1 OR51I1 OR51M1

1.55e-0444433164
GeneFamilyMitochondrial ribosomal proteins

MRPL15 MRPL10 MRPL2

8.74e-0479433646
GeneFamilyNucleoporins

POM121 NUP153

2.62e-03324321051
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FOXM1 KLF5 SNX8 LAMA4 FRMD4B

1.82e-06161565bf70be1de418615b5442ec684552551edaf1f072
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

IL1RAPL1 LAMA4 LIMCH1 LUM FRMD4B

4.64e-061955651cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF609 ST7 LIMCH1 RAPGEF2 PTK2

5.00e-061985651996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellMacroglial-Oligodendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

DOCK5 IL1RAPL1 LIMCH1 SLC7A14 FRMD4B

5.25e-062005654dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCellMacroglial-Oligodendrocytes-OPALIN--|Macroglial / cells hierarchy compared to all cells using T-Statistic

DOCK5 IL1RAPL1 LIMCH1 SLC7A14 FRMD4B

5.25e-0620056526b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCellMacroglial-Oligodendrocytes-OPALIN---|Macroglial / cells hierarchy compared to all cells using T-Statistic

DOCK5 IL1RAPL1 LIMCH1 SLC7A14 FRMD4B

5.25e-062005651314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCellMacroglial-Oligodendrocytes-OPALIN-|Macroglial / cells hierarchy compared to all cells using T-Statistic

DOCK5 IL1RAPL1 LIMCH1 SLC7A14 FRMD4B

5.25e-062005658b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCellMacroglial-Oligodendrocytes-OPALIN----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

DOCK5 IL1RAPL1 LIMCH1 SLC7A14 FRMD4B

5.25e-06200565272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCellMacroglial-Oligodendrocytes-OPALIN|Macroglial / cells hierarchy compared to all cells using T-Statistic

DOCK5 IL1RAPL1 LIMCH1 SLC7A14 FRMD4B

5.25e-062005655f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA4 LIMCH1 SLC7A14 FRMD4B

6.04e-0694564d25f096626af873f724a8cd6454ed56e33fd9854
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA4 LIMCH1 SLC7A14 FRMD4B

6.04e-06945642fb80a08f823295fa4c3e6494bf020e5b4052f0f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KLF5 SNX8 LAMA4 FRMD4B

1.92e-0512656494bd9cfe982b41a3114885173eab55feb0fbbbae
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KLF5 SNX8 LAMA4 FRMD4B

3.61e-051485644d43efee96a6493abd78e9ca41aab73db0c80626
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KLF5 SNX8 LAMA4 FRMD4B

4.33e-051555645c7b68b59244525e3714806c205a57a2daebf423
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KLF5 SNX8 LAMA4 FRMD4B

4.90e-05160564dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KLF5 SNX8 LAMA4 FRMD4B

5.02e-05161564dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCelldroplet-Fat-Gat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNX8 CFP NCF2 FRMD4B

5.14e-05162564052f797d8bcab8fc6a43e0bffdd215c88ee12889
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABO KLF5 LIMCH1 PTK2

5.65e-05166564c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RB1 CFP NCF2 FRMD4B

7.74e-051805647af90f0e7ca001bf1fe5c860ee54c4cc8eb483bf
ToppCellmild_COVID-19_(asymptomatic)-Neutrophil|World / disease group, cell group and cell class (v2)

VRK2 KLF5 NCF2

7.91e-0566563e71738a3a84be93053d1ed20d030e4c606f8f402
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UBE2J1 COBLL1 RAPGEF2 ANKRD53

8.07e-05182564626aabfd9ac662c1d189f7c4b660482914d9e669
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UBE2J1 COBLL1 RAPGEF2 ANKRD53

8.07e-05182564a00abff41c12b71d5860c494b8c722d649fd5f36
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

ABO KLF5 COBLL1 LIMCH1

8.60e-05185564673f0c688ae6984bc8027df2da335787924f4137
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ABO KLF5 COBLL1 LIMCH1

8.96e-0518756481cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA4 ABO RAPGEF4 ZNF200

9.34e-051895640739baad9a7da511dd3d7249f84299aee88370a1
ToppCellCTRL-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

RB1 COBLL1 SNX8 PTK2

9.34e-0518956414f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IL1RAPL1 LAMA4 LIMCH1 LUM

9.53e-051905647986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA4 RTEL1 PIK3R3 LAMA4

9.53e-0519056406bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellASK454-Mesenchymal|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

WDR93 LAMA4 LIMCH1 LUM

9.73e-05191564e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IL1RAPL1 LAMA4 LIMCH1 LUM

9.73e-05191564fa380a8752de158974b2ae5e741573439719cc0d
ToppCellASK454-Mesenchymal-Fibroblast|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

WDR93 LAMA4 LIMCH1 LUM

9.73e-051915641726add3f392a061536b7aff72ba84303f4a0b1f
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

LAMA4 LIMCH1 LUM FRMD4B

9.92e-0519256462904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IL1RAPL1 LAMA4 LIMCH1 LUM

1.01e-041935649f69edc97b868d23998abc98928a2e89a885ef8a
ToppCell368C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

LAMA4 LIMCH1 LUM FRMD4B

1.03e-04194564d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ST7 COBLL1 LIMCH1 FRMD4B

1.03e-0419456497534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell368C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

LAMA4 LIMCH1 LUM FRMD4B

1.03e-04194564e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COBLL1 RAPGEF4 LAMA4 LUM

1.07e-0419656440e6900a0d56088a40d37ec312f53207ea952602
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF609 ST7 LIMCH1 RAPGEF2

1.07e-04196564ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COBLL1 RAPGEF4 LAMA4 LUM

1.07e-041965647acd782a587b7d331517f60daa8b5c2177bedfc7
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IL1RAPL1 LAMA4 LUM FRMD4B

1.07e-0419656422538376a95fe3afe8639a216a5497087aa94110
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IL1RAPL1 LAMA4 LUM FRMD4B

1.07e-041965641450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COBLL1 RAPGEF4 LAMA4 LUM

1.07e-0419656473f029d2b276776d6c24356b14c6592c9cb74bd5
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COBLL1 RAPGEF4 LAMA4 LUM

1.07e-041965640b247cf981981ae61aca5de82ef687e8d783c9ef
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IL1RAPL1 LAMA4 LUM FRMD4B

1.10e-0419756431a1852911bda38543916585fda34255fd62a134
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IL1RAPL1 LAMA4 LIMCH1 LUM

1.10e-041975642f72fd9a5b6d62c24a95ed2246194ea7458c0f12
ToppCell(4)_Endothelial_cells-(41)_EC-arteriolar|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

PIK3R3 RAPGEF4 LAMA4 FRMD4B

1.10e-04197564482e3f8926880afed88ed37553ed2b5ed58b8c99
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RB1 CFP NCF2 FRMD4B

1.12e-04198564af682919a874d60f579e854c274dc47063015ea9
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK5 ST7 COBLL1 LIMCH1

1.14e-041995648587bd98de7767a575088afbea07a1feb4516b9b
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK5 ST7 COBLL1 LIMCH1

1.14e-041995645cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF609 LIMCH1 RAPGEF2 PTK2

1.14e-0419956494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
DrugDaunorubicin hydrochloride [23541-50-6]; Down 200; 7uM; MCF7; HT_HG-U133A

KLF5 PIK3R3 ZNF200 RAPGEF2 BRD1 NUP153

6.44e-061905564983_DN
DrugCefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; HL60; HT_HG-U133A

ELOA ZNF609 RB1 RTEL1 UTP20 RAPGEF2

7.47e-061955566159_DN
Diseasetyrosine-protein kinase receptor TYRO3 measurement

ABO MGA

7.21e-058482EFO_0020829
Diseasetotal blood protein measurement

ZNF438 NCOR2 ZNF609 ABO SNX8 NSUN7

8.58e-05449486EFO_0004536
DiseasePancreatic Neoplasm

ABO RB1 KLF5

5.85e-04100483C0030297
DiseaseMalignant neoplasm of pancreas

ABO RB1 KLF5

6.20e-04102483C0346647
Diseaseglucose tolerance test

ABO COBLL1

8.86e-0427482EFO_0004307
DiseaseD dimer measurement

ABCA4 ABO

1.09e-0330482EFO_0004507
Diseasefear of minor pain measurement

DOCK5 RAPGEF2

1.17e-0331482EFO_0008340
Diseaseintraocular pressure measurement

ABCA4 ABO ST7 KLF5 LUM

1.39e-03509485EFO_0004695
Diseaseendometrial carcinoma (is_marker_for)

NCOR2 PTK2

1.41e-0334482DOID:2871 (is_marker_for)
Diseaseneuroimaging measurement

ZNF438 VRK2 ABO RPL13AP3 RAPGEF2 FRMD4B PTK2

1.62e-031069487EFO_0004346
DiseaseMalignant neoplasm of breast

FOXM1 ZNF438 ABCA4 RB1 UTP20 CFP ELP3

1.66e-031074487C0006142
Diseaseovarian carcinoma

NHLRC1 ABCA4 LAMA4 NUP153

1.83e-03321484EFO_0001075

Protein segments in the cluster

PeptideGeneStartEntry
PSYPALIIDPKMPRV

BRD1

941

O95696
LPRMVYPQPKVLTPC

ABO

66

P16442
KPLLMGKILYTPDSP

ABCA4

391

P78363
YIIVKVPPDMNSPPL

CBLL2

326

Q8N7E2
IPKIGMTTYKIVPPK

COBLL1

726

Q53SF7
FIKLSPPMLLKEPYK

RB1

226

P06400
PPMLLKEPYKTAVIP

RB1

231

P06400
IPFSKPVKVYIMPKP

INTS4

946

Q96HW7
QPTEMPKPIYRKPTV

ANKRD53

366

Q8N9V6
PKPIYRKPTVKRPTM

ANKRD53

371

Q8N9V6
YPTLMEPVLLPKEAP

NCOR2

1926

Q9Y618
PKEVKLSVPMPYTLK

NCF2

341

P19878
PVYIPTPSVIEPMKP

MGA

1171

Q8IWI9
PLTDKPPKLLYPMES

IL1RAPL1

236

Q9NZN1
PPKLLYPMESKLTIQ

IL1RAPL1

241

Q9NZN1
PPMLNPIIYSVKTKE

OR51I1

286

Q9H343
PPMLNPIIYSIKTKE

OR51M1

296

Q9H341
PPLINPILYSVKMKE

OR51S1

291

Q8NGJ8
LCTPLLPKYPPTVSM

CFP

406

P27918
GIPPPYDKKKRMVVP

RPL13AP3

21

Q6NVV1
PPSMIKVVPAYVPTP

POM121

1011

Q96HA1
LIFYIEMDPPALPPK

PIK3R3

26

Q92569
KMPKEYPLNIGEKPP

FRMD4B

461

Q9Y2L6
VKPVMSLPPSYKDKP

DOCK5

1431

Q9H7D0
YKPLDPKDIRLPPPM

CHERP

666

Q8IWX8
VPEKIKIKPAPYPMG

ELOA

716

Q14241
IAAVPPQYRKVLMPK

ELP3

61

Q9H9T3
LKLKSVPMVPPGIKY

LUM

56

P51884
KMKPLLPRVSSYLVP

FOXM1

366

Q08050
PKMPYEPLTPVLYLS

GLB1L2

381

Q8IW92
LGKPEEFPVPKPMVT

NHLRC1

346

Q6VVB1
KAVPMLTPKPYSQPK

LIMCH1

531

Q9UPQ0
LSLYMKPPVKRPELT

LAMA4

861

Q16363
LPYPPRMDPRVVLKM

RTEL1

646

Q9NZ71
DKVKPYLPMIIAPLF

UTP20

2661

O75691
LTVAKLEPPLIPFMP

RAPGEF4

911

Q8WZA2
PKRMLPPEELVPYYT

MRPL15

201

Q9P015
LHKFPYRMVPALPPK

SNX8

121

Q9Y5X2
LKPIKIVLPPVFMPF

NSUN7

646

Q8NE18
KIQPAPPEEYVPMVK

PTK2

941

Q05397
VPKYLLEMKSLILPP

ST7

416

Q9NRC1
REKIDPLVPQPPMYL

TEX45

486

Q8NA69
PIFMAPQKYLPPLRI

CNBD2

546

Q96M20
NPKKLPYMAPCLPFV

SLC7A14

621

Q8TBB6
LYPSRKKVPVKDLPP

RAPGEF2

1061

Q9Y4G8
KLMAVTEYIPPKPAI

MRPL10

46

Q7Z7H8
PPSLYLSPELRCMPK

SPEM2

231

Q0P670
LAVYKPPKVSLMPAT

TAPBP

286

O15533
LKPIQPKPTVMGEPF

ZNF609

701

O15014
RIVLPPEYPMKPPSI

UBE2J1

61

Q9Y385
PEYPMKPPSIILLTA

UBE2J1

66

Q9Y385
IRPLPPMKSYVKLPS

MRPL2

286

Q5T653
YPPVQRLMTPKPVSI

NUP153

361

P49790
VVPMPPKPKQSFILR

ZNF200

6

P98182
VYIMKIKPPKPVTGT

WDR93

281

Q6P2C0
EPLPPVIYTMENKPI

TRAPPC10

6

P48553
FPVPEEPPVKKLMRT

ZBED1

521

O96006
RQSMSPKYLKVIPPI

WDR87

2591

Q6ZQQ6
SVPKGKLPIPPYSRM

ZNF438

286

Q7Z4V0
MPPKRNEKYKLPIPF

VRK2

1

Q86Y07
EMEKYLTPQLPPVPI

KLF5

91

Q13887